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Syncope – Epidemiology,
Classification & Pathophysiology
Professor Rose Anne Kenny
Definition
Syncope is defined as TLOC due to cerebral
hypoperfusion, characterized by a rapid onset,
short duration, and spontaneous complete
recovery.
Epidemiology
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Cumulative prevalence syncope
Continued…
Incidence of seizures in different age groups
Stephen, L.J. and Brodie, M.J., 2000. The Lancet
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Bhangu J, .., Kenny RA . PLOS ONE 2017
Fall/Faint previous 12 months in 8504 adults > 50
yrs
0
5
10
15
20
25
30
50 - 64yrs 65 - 74yrs 75+yrs
Syncope Falls Non-accidental fall/syncope
1:5 Injury requiring medical attention
29%
Unexplained Falls
Pre
vale
nce
(%
)
33% 41%
2018 ESC Guidelines on Syncope – Michele Brignole & Angel Moya
EHJ Doi:10.1093/eurheartj/ehy037
Identification of unexplained falls
Falls
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PATHOPHYSIOLOGY