Download - Samidirect business-manual
Healthy, Wealthy & Wise
Healthy, Wealthy & Wise
No. 30 & 31, 5th Cross,5th Block,Koramangala, Bangalore - 560034,Karnataka, India.
Tel: 91 80 4038 1800Fax: 91 80 4038 1838 [email protected]
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Sami Labs WorldwideSami Labs WorldwideSami Labs Worldwide
Dr. Muhammed Majeed is the inspiration and motivation
behind Sami and the Sabinsa Group of Companies. Dr. Majeed
has a Ph.D in Industrial Pharmacy. After a decade and half of
working with respected names in the American pharmaceutical
industry, Dr. Majeed first set up Sabinsa Corporation in New
Jersey, USA in 1988. He later set up Sami Labs Limited Bangalore,
India in 1991, with the vision of research, development and
marketing of a new genre of products – natural therapeutics.
Over the past two decades, the organization has grown into a
health science multinational with presence in USA, Europe,
India, Japan, Australia, China, UAE, South Africa and Brazil. It
employs over a 1000 people with four manufacturing locations
in India and one in USA. Its research facility in Bangalore has
over a hundred scientists involved in specialized work in the
areas of phytochemistry, organic chemistry, biochemistry,
tissue culture and plant biotechnology.
Today, Sami holds a strong intellectual property portfolio with
several US and international patents to its credit apart from
awards and recognitions worldwide.
Founder speaksFounder speaksFounder speaks
Dr. Muhammed Majeed
““
Dear Friend, Congratulations on your decision!
A little over 3 decades ago, I went from a small town of South India to the United States of America seeking fulfillment of my dreams. Today, with a business conglomerate spread across the world, I can confidently say that the future belongs to those who believe in the beauty of their dreams.
The aspiration to dream and the conviction to follow their dreams is what sets apart the extraordinary from the ordinary. Congratulations for choosing to be among the extraordinary.
Now we are in it together. You have chosen the right place and the right means. The awesome combination of extensively researched products and a revolutionary business plan is a definite formula for success. Believe me, making money has never been such fun !
We are with you at every step to help you fulfill your dreams and reach greater heights.
Welcome again,
Dr. Muhammed Majeed
In Nature lies the power… to heal and to protect. A truth
that our ancestors had known and practiced centuries ago
has only now come to the understanding of the modern
generation. Sami was born out of this realization, and exists
for the sole purpose of bringing the healing power of
Nature to cure and nurture human life.
The miraculous properties of nature can be fully extracted
only through innovative use of scientific technology. Thus,
based on market-oriented research, the company
integrates modern scientific techniques with ancient
wisdom of Ayurvedic herbal armamentariums to produce
new drug molecules – health solutions that have brought
back smiles to millions of faces around the world.
As one of the world's largest health science company, the
Sami Group has a responsibility towards the people.
Through innovative research, deep understanding of the
market and production excellence, Sami Labs Ltd. will
provide consumers with the best of natural product
solutions for a healthier and wealthier life
Where innovation is a tradition
From the desk of the CEOFrom the desk of the CEOFrom the desk of the CEO
Mr. Rajesh Kumar, CEO
“
“
Welcome on board Sami Direct. As we embark on this journey of fulfilling the dreams of our Business Associates by bringing nutrition to everyday life , we are glad to have you with us.
Sami Direct is the culmination of relentless Research and development for over 22 years. We at Sami Direct are committed to offer you an unrivalled range of Nutraceutical followed by cosmeceutical products which has been acknowledged by the world over for its highest quality and safety standards.
With the perfect blend of world class products and a revolutionary business plan, for you it is a lifetime opportunity not just to enhance your health, but a fruitful and lasting career which would heighten your income.
Your journey as an independent Entrepreneur will be supported by extensive training programmes by the masters themselves as a step by step guide in realizing and fulfilling your dreams, and to top it all recognition and rewards for every milestone that you reach.
Our team of professionals with proven experience in the industry whose constant endeavour will be to offer solutions which are most beneficial to its distributors & customers. A thousand mile journey starts with the single step, and I am confident that you have taken the right step.
I wish you great success and great health.
Once again I welcome you on board.
Yours Truly,
Rajesh Kumar
Our facilitiesOur facilitiesOur facilities
Solid foundation for our dreams
Sami Labs has created a benchmark for standardized herbal medicines
globally. With six highly advanced, state-of-the-art manufacturing units,
which adhere to the strictest quality and safety norms, Sami Labs focuses
all its efforts towards creating effective and safe products.
Every facility is in compliance with rules and regulations. All effluent
streams are treated and disposed off significantly. Reflecting the internal
system of quality and regulatory requirements, the facilities are certified
by National Sanitary Foundation of USA and the Orthodox Union (Kosher)
of USA.
Its Good Manufacturing Practices (GMP) registration is just one of the
many aspects that reflect the company’s commitment to high quality
products.
Sami Labs, Bangalore, India
Manufacturing facility, Kunigal
Biotechnology Facility, Nelamangala
Manufacturing Facility, Hyderabad
Super Critical Fluid Extraction , NelamangalaFacility
Continuous Extraction Unit, Dobaspet
Sabinsa Utah, USAManufacturing,
Research & DevelopmentResearch & DevelopmentResearch & Development
Finding new light
Recognized by the Department of Scientific and Industrial Research, Sami
R&D is a multi-disciplinary division pursuing diverse fields of research.
The R&D also works closely with the Government of India and the Indian
Pharmacopoeia Committee on preparation of Standard Operating
Procedures for Ayurvedic herbs and monographs for Indian herbs.
Equipped with the best of talent and facilities, Sami research is geared to
constantly innovate and sustain high quality output to broaden the
product portfolio, enrich its intellectual property and build up a robust
pipeline of products.
Natural Drug Division:
Phytochemistry:
Synthetic Chemistry :
This division focuses on identifying, isolating and developing drugs from various natural source having a potential to become a drug.
This division does the isolation and development of active ingredients from herbs for various nutraceutical and therapeutic applications.
Sami Labs has set up a strong synthetic chemistry division to manufacture some of the synthetically derived nutraceuticals. This division currently works on:
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Development of drug and drug intermediates
Development of selenium amino acid
Development of chiral molecules
Development of peptides for cosmeceuticals
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Method development
Validation
Development of specification for all products and
Quality control & Quality Assurance
Biological Research:
This department tests the safety and efficacy of the products developed in the R&D i.e. cosmeceuticals and nutraceutical products. They have developed several in vitro models for testing anti-obesity, anti-diabetic, anti-ageing and several other disease conditions. Non-animal toxicity testing is also undertaken.
It is a key function in the R&D and it supports all the development activities.
Their important roles are:
This department develops natural cosmetic products that have properties to rejuvenate and protect the skin from environmental pollution, toxic chemicals and Ultraviolet A and B radiation resulting in wrinkling, hyper pigmentation (excessive tanning) and inflammations (sunburn). The department also develops dosage formulations in capsules, tablets etc for the nutraceutical products.
Sami Labs ventured into Biotechnology in the year 2000. LactoSpore® is the first commercial production using the in-house R&D technology. This division is currently involved in the production of high-value enzymes as well as other probiotics .
The scientists here develop high-yielding varieties of medicinal plants & multiply them through tissue culture techniques in the laboratory.
Analytical R&D:
Formulations R&D:
Biotechnology:
Tissue Culture:
Intellectual PropertiesIntellectual
Properties Intellectual
Properties
63 International patents and still growingWe have 63 patents to our credit, as on September 2010.
US PATENTS
Title No Brand /IngredientPatent
Title No Brand /IngredientPatent
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US 5,536,506
US 5,744,161
US 5,783,603
US 5,804,596
US 5,861,415
US 5,972,382
US 6,054,585
US 6,436,991
US 6,607,712
US 6,653,327
US 6,689,400
US 6,770,782
US 6,794,537
US 6,849,645
US 6,960,300
US 6,982,273
US 6,998,502
US 7,345,196
US 7,014,874
US 7,063,861
US 7,160,562
US 7,202,270
US 7,217,546
US 7,253,324
US 7,300,682
US 7,371,889
US 7,378,442
US 7,514,573
US 7521580
US 7582314
BioPerine®
BioPerine®
Citrin®K
ForsLean®
3Curcumin C Complex®
BioPerine®
BioPerine®
Gugulipid®
Coleus Oil
Tetrahydrocurcuminoids
ZeaLutein®
Citrin® K
Methyselene
Cosmoperine®(THP)
Forskolin Eye Drops
Methyselene®
Efflornithine
Efflornithine
SelenoForce®
GarCitrin®
Metformin-Like Compounds
Liposol
Policosanol
Stilbenes
Cococin™
AKBBA+NSAIDS
AKBBA+NSAIDS
3-Aminotetrahydrofurans
3Curcumin C Complex
®
Use of Piperine to increase bioavailability of nutritional compounds
Use of Piperine as a bioavailability enhancer
Potassium hydroxycitrate for the suppression of appetite and induction of weight loss
Novel Method of preparing a Forskolin composition from Forskolin extract and use of Forskolin for promoting lean body mass and treating mood disorders
Bioprotectant composition, method of use and extraction process of Curcuminoids
Use of Piperine as a bioavailability enhancer
Process for making high purity piperine for nutritional use
Composition and method containing products extracted from Commiphora Sp. for prevention and treatment of abnormal cell growth and proliferation in inflammation, neoplasia and cardiovascular disease
Composition and methods containing an antimicrobial essential oil extracted from Coleus Forskohlii.
Cross regulin composition of turmeric-derived Tetrahydrocurcuminoids for skin lightening and protection against UVB rays
Process of obtaining composition of stable lutein and lutein derivatives
Process for the production of potassium hydroxy citric acid and compositions containing the potassium hydroxy citric acid
Manufacturing Processes for Se-alkylselenocysteine, Se-allylselenocysteine, Se-arylselenocysteine
Method of increased bioavailability of nutrients and pharmaceutical preparations with tetrahydropiperine and its analogues and derivatives
Process for preparing water soluble diterpenes and their applications.
Composition and methods containing bioavailable Se-methyl-L-Selenochysteine for human and veterinary.
A Convenient Process of Manufacture For Difluromethylornithine And Related Compounds
A Convenient Process of Manufacture For Difluromethylornithine And Related Compounds
Compositions and Methods containing Allium Sativum Linn, (Garlic) naturally enriched with organic selenium compounds for nutritional supplementation
Bioavailable compositions of Natural and Synthetic HCA
Compositions and methods containing natural compounds from non-conventional sources that are useful in maintaining normal blood sugar levels
Convenient stable non-hygroscopic crystalline solid forms of racemic and chiral LA-plus salts process for their manufacture and uses
Commercially viable process for high purity of fatty alcohol C24 to C36 and its cosmetic application for skin hair and nails
Process for the synthesis of biologically active oxygenated compounds by dealkylation of the corresponding alkylethers
Method of preparation and use of coconut water in mammalian tissue nourishment, growth, and healthy maintenance
New Chemical entities with multiple modes of anti-inflammatory action
New Chemical entities with multiple modes of anti-inflammatory action
Process for the Manufacture of Chiral And Racemic Forms of 3-Aminotetrahydrofurans, their Salts and Derivatives
Non-cytotoxic synthetic analogues of (1E, 6E )-1,7-Bis (4 hydroxy-3-methoxyphenyl)-1,6-heptadiene-3, 5-dione and therapeutic applications thereof in cystic fibrosis)
Composition and methods for the management of hyperproliferative dermatological conditions
INTERNATIONAL PATENTS
Title No Brand /IngredientPatent
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AU2006235807
AU773081
CA2247467
CA2281562
EP0810868
EP0839037
EP0977564
EP1171144
EP1254209
EP1341547
EP1328263
GB2380675
IN229695
IN235492
IN238950
JP3953513
JP4098985
JP4205943
JP4227409
MX260326
NZ514884
NZ518116
NZ552027
NZ552997
NZ545765
NZ568652
PH/12006500481
RU12836
RU2366412
SG121197
SG136165
ZA2006/01898
ZA2007/0694
Tetrahydrocurcuminoids
GarCitrin®
BioPerine®
ForsLean®
BioPerine®
3Curcumin C Complex®
ForsLean®
Tetrahydrocurcuminoids
GarCitrin®
Cococin™
Tetrahydrocurcuminoids
Cosmoperine®(THP)
Policosanol
Forskolin Eye Drops
BioPerine®
Cosmoperine®(THP)
GarCitrin®
ZeaLutein®
Forskolin Eye Drops
Tetrahydrocurcuminoids
GarCitrin®
Forskolin
Forskolin Eye Drops
Forskolin-Div1
Forskolin Eye Drops
Forskolin Eye Drops
Forskolin Eye Drops
Forskolin Eye Drops
Use of Tetrahydrocurcuminoids to Regulate Physiological and Pathological Events in the Skin and Mucosa
Bioavailable compositions of Natural and Synthetic HCA
Use of Piperine as a Bioavailability Enhancer
Forskolin for promoting Lean Body Mass
Use of Piperine as a bioavailability enhancer
Bioprotectant composition, method of use and extraction process of Curcuminoids
Forskolin For Promoting Lean Body Mass
Use of Tetrahydrocurcuminoids to Regulate Physiological and Pathological Events in the Skin and Mucosa
Bioavailable compositions of Natural and Synthetic HCA
Coconut water and its method of preparation
Process of making and method of use of tetrahydrocurcuminoids to regulate physiological and pathological events in the skin and mucosa cells
Method of increased bioavailability of nutrients and pharmaceutical preparations with tetrahydropiperine and its analogues and derivatives
A process for obtaining high purity fatty alcohols
A method for solubilizing forskolin and a composition thereof
A Process of preparing a synergistic composition for treating hyperproliferative dermatological conditions.
Use of Piperine as a Bioavailability Enhancer
Method of increased bioavailability of nutrients and pharmaceutical preparations with tetrahydropiperine and its analogues and derivatives
Bioavailable compositions of Natural and Synthetic HCA
Process of obtaining composition of stable lutein and lutein derivatives
Process of preparing water soluble diterpenes and their applications
Use of tetrahydrocurcuminoids to regulate physiological and pathological events in the skin and mucosa
Bioavailable compositions of Natural and Synthetic HCA
Compositions and methods for the management of hyperproliferative dermatological conditions
Composition for physiological increase of male and female hormones with diterpene forskolin and its derivatives
Process For Preparing Water Soluble Diterpenes And Their Applications
Commercial Process for Making Forskolin and its Derivatives
Process for preparing water soluble diterpenes and their applications
Process for Preparing Water Soluble Diterpenes and Their Applications
Compositions and methods for the management of hyperproliferative dermatological conditions
Process of preparing water soluble diterpenes and their applications
Compositions and methods for the management of hyperproliferative dermatological conditions
Process for preparing water soluble diterpenes and their applications
Composition and methods for the management of hyperproliferative dermatological Conditions.
AU-Australia
CA-Canada
EP-Europe
GB-Great Britain
IN-India
JP-Japan
MX-Mexico
NZ-New Zealand
PH-Philippines
RU-Russia
SG-Singapore
US-United States
ZA-South Africa
Intellectual PropertiesIntellectual
Properties Intellectual
Properties
Recognition Recognition Recognition The proof of excellence
1994: Dr. Majeed receiving the National Award for Quality and Innovation (Basic Drugs) from (Late) Dr. Shankar Dayal Sharma, President of India.
2008: Dr. Majeed receiving the Certificate of Excellence for Exports from Federation of Indian Export Organisations.
2006-07: Dr. Majeed receiving the Export Excellence Award from Federation of Karnataka Chamber of Commerce & Industry.
2002: Dr. Majeed receives DSIR Award for R&D efforts in the category of "Chemical and Allied Industries"
1996-97: Dr. Majeed receiving the National Award from (Late) Dr. Shankar Dayal Sharma, President of India, awarded by Spice Board.
2009: Sabinsa Received Thomas Alva Edison Patent Award for GarCitrin from Research & Development Council of New Jersey , USA
2004: Sabinsa Received Thomas Alva Edison Patent Award for ForsLean from Research & Development Council of New Jersey , USA
1998-99: Certificate of Honour for Outstanding Performance in the Export of Spices/Spice Products from India issued by Spices Board.
2005: Sabinsa Received Thomas Alva Edison Patent Award for Tetrahydropiperine from Research & Development Council of New Jersey , USA
2008: Export Excellence Award.
2008: Certificate of Excellence for Export Achievement from the Ministry of Commerce, Government of India being received by Mr. K.B. Siva Prakash.
Recognition Recognition Recognition The proof of excellence
2004: Dr. Majeed honored with the prestigious Ellis Island Medal of Honor from National Ethnic Coalition of Organizations, USA.
2010: Dr. Majeed received the Daniel B. Stateman award for distinguished alumni from Dr. David Taft at Long Island University’s 121st graduation ceremony in Brooklyn.
Dr. Majeed Receiving distinguished alumni Award of Trivandrum Medical College from Hon.Vayalar Ravi, Minister for Overseas Indian Affairs.
2009: Mr. Shaheen Majeed, (Marketing Director for Sabinsa) receiving Herbal Industry Leader Award from the American Herbal Products Association
2008 Sabinsa Corporation is the recipient of Frost & Sullivan’s 2008 North American Personal Care Ingredient Green Excellence of the Year Award. The award is in acknowledgment of Sabinsa’s strategically balanced green product offering, proactive and sustainable marketing practices, and the continuous ability to satisfy client needs in an increasingly diverse and green-conscious market space
2006 Sabinsa Corporation was awarded by Nutrition Business Journal (NBJ) * A product merit award for their branded L –(+) – Selenomethionine compound, Selenium SeLECT®
* An investment in science and Research award for Forslean® , the company’s branded and patented coleus forskohlii extract ingredient used to improve body composition.NBJ is a research, publishing and consulting company serving the nutrition, natural Products and alternative health care industries.
2003 Best Export Award - Overall GOLD 2002 Award for Highest Export of Value Added Spices by Spices Board, Govt. of India, Ministry of Commerce &
Industry. 2002 Award for Highest Export of Newly Developed Spice Products by Spices Board, Govt. of India, Ministry of
Commerce & Industry. 2002 Export Award in Recognition of Company’s Performance in “Chemicals Category” for the year 2001 – 02
by the Federation of Karnataka Chambers of Commerce & Industry (FKCCI) 2002 Award for Excellence in Export Achievement under 100% EOU Scheme in “Agro & Food” Sector in
Karnataka from Govt. of India, Ministry of Commerce & Industry for the year 2001-02 2001 Award for Achieving the Highest Export of Newly Developed Value Added Spice Products from India
during the year 1999-2000 by Spices Board, Govt. of India, Ministry of Commerce & Industry 2001 Award for Achieving the Highest Export of Value Added Spices from India during the year 1999-2000 by
Spices Board, Govt. of India, Ministry of Commerce & Industry 2001 Award for Outstanding Performance in the Export of Spices/Spice Products from India during the year
1999-2000 by Spices Board, Govt. of India, Ministry of Commerce & Industry 2001 Approval of In-house Research & Development Unit u/s 35(2AB) of Income-Tax Act 1961 from Govt. of
India, Ministry of Science & Technology, Department of Scientific and Industrial research. 2000 Certificate of Honour for Outstanding Performance in the Export of Spices/Spice Products for the year
1998 – 99 from India issued by Spices Board, Govt. of India, Ministry of Commerce & Industry 1997 Recognition of In-house Research & Development facility (Renewable from time to time) 1997 Recognised Export House from Govt. of India, Ministry of Commerce, DGFT, New Delhi.
1995–96 Certificate of Merit for Outstanding Export Performance in Spice Products, Vegetable Extracts, Organic Fine Chemicals, Essential Oils, Extracts & Oleoresins,Modified Starches & Enzymes, etc., from Govt. of India, Ministry of Commerce.
Corporate Social Responsibility Corporate
Social Responsibility Corporate
Social Responsibility
Considering the importance of biodiversity of medicinal plants and to
maintain the sustainability for future generations, the company has taken
up a successful initiative over the last 10 years by undertaking and
promoting large scale commercial cultivation of medicinal plants globally.
SAMI initiated almost a decade ago, medicinal plant cultivation with a
handful of farmers. Over the years this effort has translated into a large
scale cultivation model involving more than 40000 acres and supporting
thousands of farmer families.
Sami supports its farmers with a buy back guarantee , crop insurance, bank
finance and ensures they receive a reasonable price for the produce
avoiding intermediaries.
Today, this successful model is being replicated in Africa and South East
Asia.
Products Products Products
Sami Direct is a committed to offer you an unrivalled range of
Nutraceuticals followed by cosmeceuticals which has been acknowledged
by the world over for its highest quality and safety standards. Supported by
our own Sami labs R&D and Clinical Studies, Sami Direct is all set to usher in
a novel range of nutraceuticals and cosmeceuticals with a holistic
approach in leading the world to better health.
Sami has also developed the strength and infrastructure to offer services in
the areas of:
Healing in myriad ways
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Customized Product Development
Formulation Development
Contract research
Clinical research
Non animal in-vitro efficacy and toxicity studies
Analytical Studies
Women 40+
®OsteoStrong
As women age, the body undergoes many changes and the major concern is
menopause, when hormone levels begin to drop and the menstrual cycle ceases.
Menopause is the permanent cessation of reproductive fertility some time
before the end of the natural life span. The decline in estrogen levels associated
with menopause puts women at increased risk for declining bone density and
fractures.
Osteoporosis literally means porous bone and is sometimes referred to as the
“silent disease” because bone loss occurs without symptoms. Although
osteoporosis can strike at any age, chances of it developing, increases with age.
Statistics show that one in two women of age 50 and older usually suffer an
osteoporosis-related fracture in their lifetime. Fortunately osteoporosis can be
prevented or treated.
OsteoStrong® by Sami Direct is a health supplement for 40+ women who face an
increased risk of declining bone density and fractures. Loaded with natural
ingredients like Calcium Citrate malate, Soy extract, Red Clover extract and
BioPerine®, OsteoStrong® not only strengthens your bones from within but also
helps prevent osteoporosis and postmenopausal symptoms in women.
Binds at estrogen receptors and
prevent the body from over-
producing estradiol
Mimics the action of estrogen &
along with most bio-available form
of calcium, helps in Bone Mineral
Density
Boosts progesterone expression and
help to normalize the body's
important estrogen to progesterone
ratio
KEY BENEFITS
Each Tablet contains:
Ingredient
Soy extract (40% Isoflavones)
Red Clover extract
Calcium Citrate malate
BioPerine®*
Quantity per Tablet
30 mg
10 mg
500 mg
5 mg
Suggested Use :One tablet twice daily
*Patented – US & International Patents
References:
1. Ajmandi, Bahram, H, Journal of the American College of Nutrition, Vol. 20, No. 5, 398S–402S(2001).
2. Van de Weijer, P., Isoflavones from red clover (Promensil®) significantly reduce menopausal hot flush symptoms compared with placebo. Maturitas, Volume 42, Issue 3, Page 187.
Sami Direct’s Orgnanic Spirulina contains Spirulina, a natural source of vitamins, minerals, antioxidants and other nutrients, in combination with *Bioperine®, a patented bioavailability enhancer derived from black pepper fruit that enhances their uptake and utilization.
SpirulinaSpirulina is a marine algal source that supports optimal health and wellness, due to high concentration of essential nutrients. Spirulina is produced primarily from two species of cyanobacteria: Arthrospira platensis and Arthrospira maxima.
Spirulina is a microscopic, blue-green algal culture (a free floating filamentous cyanobacterium). Spirulina for dietary supplements is derived from Arthrospira platensis or Arthrospira maxima), Spirulina is a rich source of vegetable proteins, iron, pro-vitamin A carotenoids, vitamin B (thiamine), B (riboflavin), B 1 2 3
(niacin), B (pyridoxine), B (cobalamin), vitamin C, vitamin D, vitamin E, folate, 6 12
vitamin K, biotin, pantothenic acid, beta carotene (source of vitamin A), inositol, essential amino acids, and the rare essential fatty acid, GLA (gamma-linolenic acid).
Studies show that Spirulina preparations have significant antioxidant activity, benefit metabolism, detoxification, and immune functions; and support the management of inflammation and allergies.
Rich in antioxidant
Boosts energy and Cellular Health
P r o m o t e s M e t a b o l i s m ,
Detoxification & Immune Functions.
Supports the Management of
inflammation and allergies.
KEY BENEFITS
Suggested Use :One tablet twice or thrice daily
References:
1. Park, H.; Lee, Y.; Ryu, H.; Kim, M.; Chung, H.; Kim, W. (2008). "A randomized double-blind, placebo-controlled study to establish the effects of spirulina in elderly Koreans". Annals of nutrition & metabolism 52 (4): 322–328.
2. Lu, H.K., Hsieh, C.C. Hsu, J.J., Yang, Y.K., & Chou, H.N. (2006). "Preventative effects of Spirulina platensis on skeletal muscle damage under exercise induced oxidative stress". European Journal of Applied Physiology 98 (2): 220–226
Alcoholism or alcohol dependency is a disease that manifests the following four
symptoms: craving, loss of control, physical dependence and addiction. Alcohol
hangover, an after-upshot of dehydration and intoxication, is a common
condition that causes substantial impairment to affected individuals. The
dehydration of the body is caused by alcohol, which is a diuretic. Hangover is
characterized by the constellation of unpleasant physical and mental symptoms
that occur after heavy alcohol drinking.
When alcohol is consumed, the liver breaks it down primarily into a toxic
substance called acetaldehyde. The build up of acetaldehyde in the liver results
in hangover symptoms such as headache, nausea, irritability and fatigue.
Accumulation of acetaldehyde at higher concentrations leads to the
development of physical symptoms of hangover, which include rapid pulse,
sweating, skin flushing, increased sensitivity to light and sound, redness of the
eyes, muscle aches and thirst. The dehydrating effect of alcohol is also
responsible for morning dizziness, tiredness and general body weakness.
Liver Support is a unique formulation from Sami Direct that offers a holistic
approach to the problems associated with alcohol dependency. It effectively
maintains balance, manages stress, helps to sober down and deal with the
effects of hangover.
Provides better ‘morning after’
effects
Helps to deal with the symptoms of
nausea, headache and dehydration
Effectively eliminates acetaldehyde,
the toxic by-product of alcohol
intake
Helps maintain healthy liver
functions
KEY BENEFITS
Each Capsule contains:
Ingredient
*
*
3Curcumin C Complex®
Fabenol®
Vit B12
Vit B6
Folic acid
Phyllanthus amarus
BioPerine®
Quantity per Capsule
250 mg
90 mg
5 mcg
1.5 mg
100 mcg
60 mg
5 mg
Suggested Use :One capsule twice daily
*Patented – US & International Patents
References:
1. Bharat B. Aggarwal Chapter 23 Curcumin Derived from Turmeric (Curcuma longa):a Spice for All Seasons. Phytopharmaceuticals in Cancer Chemoprevention. © 2005 by CRC Press LLC. p 349-387.
2. S.Priya and PR Sudhakaran. Curcumin-induced recovery from hepatic injury involves induction of apoptosis of activated hepatic stellate cells. Indian. J. Biochem. Biophys. Vol 45, 2008; pp. 317-325.
3. Chidi U. Igwe et al.,Assessment of the hepatic effects, phytochemical and proximate compositions of Phyllanthus amarus African Journal of Biotechnology Vol. 6 (6), pp. 728-731, 19 March 2007. pp 728 – 731.
Organic SpirulinaMaintaining Good Health For Healthy Liver
Liver Support
Each Tablet contains:
Ingredient
Spirulina
BioPerine®*
Quantity per Tablet
400 mg
2.5 mg
*Patented – US & International Patents
A joint is formed by the ends of two or more bones that are connected by thick
bands of tissue called ligaments. For example, the knee joint is formed by the
lower leg bone, called the tibia or shinbone, and the thighbone, called the femur.
The hip joint is a ball-and-socket joint, formed by the ball, or femoral head, at the
upper end of the thighbone, and the rounded socket, or acetabulum, in the
pelvis.
Joint pain is a very common problem prevailing in almost every part of the world.
It is basically a symptom and not a disease and it has eventually become a part of
everybody’s life, especially aged people
Arthritis is a group of conditions involving damage to the joints of the body. The
most common form, osteoarthritis (degenerative joint disease) is a result of
trauma to the joint, infection of the joint or age.
Other arthritis forms are rheumatoid arthritis, psoriatic arthritis and
autoimmune diseases in which the body attacks itself. Septic arthritis is caused
by joint infection. Gout is another form of arthritis, caused by deposition of uric
acid crystals in the joint, causing inflammation.
3R Power™ is a sustained release composition containing herbal extracts and
nutrients that help support healthy joints and connective tissues in the body.
Helps to overcome joint pains
Effectively reduces inflammation of
joints (arthritis)
Prevents inflammation of the
tendons (tendonitis)
KEY BENEFITS
Suggested Use :One tablet twice daily
References:
1. Research Report – Sami Labs Limited.
Optimum 1 is a unique composition containing herbal extracts and nutrients
that help to support healthy blood sugar level.
Blood sugar refers to the amount of glucose present in the blood. Normally, in
mammals the blood glucose level is maintained at a reference range between
about 3.6 and 5.8 mM (mmol/L) or 64.8 and 104.4 mg/dL. It is tightly regulated as
a part of metabolic homeostasis, by the hormone insulin. Impaired insulin
secretion due to genetic or diet and lifestyle factors, or the inability to use insulin
i.e. insulin resistance encountered sometimes in obese individuals impact
glucose homeostasis.
Failure to maintain blood glucose in the normal range leads to conditions of
persistently high (hyperglycemia) or low (hypoglycemia) blood sugar. Diabetes
mellitus, characterized by persistent hyperglycemia is the most prominent
disease related to failure of blood sugar regulation. If left unchecked, can lead to
a number of serious health problems including blindness, kidney disease, stroke
and heart disease.
Optimum®1 is a carefully formulated product from Sami Direct that contains
effective ingredients that support normal blood sugar levels, when combined
with a healthy diet and lifestyle.
® Supports healthy blood sugar levels
Support the body’s natural ability to
utilize insulin
Effectively manages Impaired
Glucose Tolerance
KEY BENEFITS
Each Tablet contains:
Ingredient
Momordicin®
Chromium Picolinate
Silbinol®
BioPerine®
*
Quantity per Tablet
100 mg
50 mcg
100 mg
2.5 mg
Suggested Use :One tablet twice daily
*Patented – US & International Patents
References:
1. DiSilvestro, R, et al. Acute Absorption of Various Types of Chromium Supplement Complexes. Accepted for presentation at the Federation of American Societies for Experimental Biology (FASEB) annual meeting, San Diego, CA, April 4, 2005..
2. Anderson, RA, et al. Lack of Toxicity of Chromium Chloride and chromium Picolinate in Rats. J Amer Coll Nut Vol. 16, No. 3 1997; 273-279.
3. Saifi, A.Q., Shinde, S., Kavishwar, W.K., and Gupta, S.R. (1971) Some aspects of phytochemistry and hypoglycaemic actions of Pterocarpus marsupium (Papilionaeceae). J. Res. Ind. Med., 6(2), 205-207.
Keep all supplements out of reach of children.
ADVANCED JOINT SUPPORT FORMULARelief Rebuild Restore • •
3 ™R PowerBlood Sugar Balance
®Optimum 1
Each Tablet contains:
Ingredient
Glucosamine HCl
Boswellin® PS
Curcumin C3 Complex®
BioPerine®
**
*
*
Quantity per Tablet
750mg
100mg
100mg
5mg
* **
Patented – US & International PatentsPatent Pending
It is a mistaken belief that in order to lose weight, one must eliminate fat from the diet. On the contrary, eliminating fats from the diet totally can be very harmful to the body as good fats are essential to the body and play critical roles in metabolism and wellness.
Essential fatty acids (EFAs) are beneficial fats chemically classified under polyunsaturated fatty acids (PUFA) that cannot be formed by the body and need to be supplied by the diet. The two primary EFAs are known as alpha-linolenic acid (Omega-3) and linoleic acid (Omega-6). Omega-9 fatty acids (oleic acid) are non-essential fatty acids, as they can be produced from the EFAs. However, deficiency does occur when the diet is deficient in EFAs.
Essential fatty acids are required for energy production in the body, cardiac function, health of hair, skin and nails, hormone production, brain function, and for the integrity of the very structure of cells. Symptoms of omega-3 fatty acid deficiency include extreme tiredness (fatigue), poor memory, dry skin, heart problems, mood swings or depression, and poor circulation.
Omega BioPlus™ contains a vegetable derived omega 3, omega 6 and omega 9 fatty acids composition in a specific scientifically validated proportion to support healthy cell membranes and cellular functions, and attractive skin, hair and nails. The fatty acids composition is combined with sesame oil antioxidants and a bioavailability enhancer derived from black pepper fruit.
It supports the liver and kidney
functions; and helps in maintaining
normal b lood pressure and
cholesterol levels.
It supports a healthy immune
system, and cardiovascular health
and wellness.
I t b e n e f i t s i n s u p p o r t i n g
cardiovascular health, joint health;
neuronal health and healthy skin,
hair and nails.
KEY BENEFITS
Suggested Use :One softgel twice daily
References:
1. Szapary, O. Philippe. The Heart Health Benefits of Omega-3 Fatty acids. Advanced Studies in Medicine. Vol 5 (6A); p-511-517.
2. Harbige L.S.; Layward L.; Morris-Downes M.M.; Dumonde D.C.; Amor S. The protective effects of omega-6 fatty acids in experimental autoimmune encephalomyelitis (EAE) in relation to transforming growth factor-beta 1 (TGF-β1) up-regulation and increased prostaglandin E2 (PGE2) production. Clinical & Experimental Immunology, Volume 122, Number 3, December 2000, pp. 445-452(8).
3. Hirose, N et al. Inhibition of cholesterol absorption and synthesis in rats by sesamin. Journal of Lipid Research Volume 32, 1991. P 629-638.
The word “Detox” means detoxifying the body from toxins and other harmful chemicals and cleansing it for proper functioning and optimal health.
Body cleansing or detoxification helps rid the body of accumulated harmful substances, such as heavy metals and environmental toxins that exert a negative effect on the health of an individual.
There are two major approaches to the detoxification programme.1. Antioxidant Support. Oxidation occurs at the cellular level, so detox must occur there as well. Any deficiency of antioxidants in the diet causes problems associated with removal of toxins .
2. Supporting healthy liver functions. A good detoxifying agent removes impurities from the blood through the liver. Liver is an important organ where toxins are processed so that they can be removed from the system. It is also responsible for detoxifying the body of poisonous substances by transforming and removing toxins and wastes.
SAMI DIRECT’s For Detoxification is a judicious blend of ingredients that can be used to provide these benefits. The ingredients have been chosen with care and formulated scientifically to offer a comprehensive and holistic support to the detoxification process.
Supports the body’s natural
mechanisms to eliminate toxins
Supports digestion
Supports the maintenance of
normal liver functions
S u p p o r t s n o r m a l m eta b o l i c
processes leading to sustained
energy levels and stamina
KEY BENEFITS
Each Capsule contains:
Ingredient Quantity per Capsule
5 mg
100 mg
100 mg
50 mg
50 mg
Suggested Use :One capsule daily upto 30 days. To be repeated after every 6 months.
References:
1. Picrorhiza kurroa Monograph – Alternative Medicine Review, Volume 6, No.3, 2001, 319 – 321.
Omega BioPlus™
EFFECTIVELY REMOVES TOXINS
For Detoxification
Each Softgel contains:
Ingredient
Omega 3 Fatty Acids
Sesamin Complex
BioPerine®*
Quantity per Softgel
500 mg
10 mg
5 mg
*Patented – US & International Patents
Peppermint oil
FenuFibers®
Licorice extract
Neem Leaf Extract
Picroliv® - Apocynin 5% (Picrorhiza kurroa)
LactoSpore® (15 mio)
10 mg
3Curcumin C Power™ offers the health benefits of quality curcuminoids from turmeric roots, in a convenient form that is better absorbed in the body. Curcuminoids are valued for their antioxidant and anti-inflammatory roles in biological systems.
Most degenerative diseases are driven by underlying chronic sub-clinical inflammation. The old view of the inflammation is that it represents the healing process. This is true to a certain extent; however when the inflammation becomes chronic, it becomes a disease.
NF-kB (Nuclear Factor-KappaB) is a cell-signaling molecule for inflammation; its activation induces the expression of cyclooxygenase – (COX-2), an enzyme that triggers tissue inflammation. NF-kB resides in the cytoplasm of the cell and is bound to its inhibitor. Injuries and inflammatory stimuli, such as free radicals, release NF-kB from its inhibitor.
NF-kB activation is a major mediator of inflammation in most diseases and inhibition of NF-kB can help prevent/delay the onset of the disease. Curcuminoids, natural compounds derived from turmeric roots, inhibit NF-kB.
3Curcumin C Power™ is a proprietary composition of Curcuminoids containing 3Sabinsa’s patented Bioprotectant Complex – Curcumin C Complex®* and the
natural patented bioavailability enhancer, BioPerine®*, derived from black pepper fruit, which enhances the absorption of curcuminoids.
F a s t - a c t i n g , l o n g - l a s t i n g ,
bioavailable Curcumin
Supports overall wellness and good
health
KEY BENEFITS
Suggested Use :One tablet twice daily
Obesity is recognized as a chronic disease almost in all countries. High
prevalence of obesity is of great public health concern because excess body fat
leads to a higher risk for premature death, type 2 diabetes, hypertension,
dyslipidemia, cardiovascular disease, stroke, gall bladder disease, respiratory
dysfunction, gout, osteoarthritis, and certain kinds of cancers.
Overweight and obesity are the results of several factors. For each individual,
body weight is determined by a combination of genetic, metabolic, behavioral,
environmental, cultural and socioeconomic influences. For the vast majority of
individuals, however, overweight and obesity are the results of excess calorie
consumption and/or inadequate physical activity. Weight management means
keeping body weight at a healthy level. LeanGard® contains an advanced
spectrum of natural ingredients that work synergistically to support satiety, lean
body mass, and a healthy body composition, with a beneficial impact on healthy
body weight.
LeanGard® is a proprietary blend of natural extracts that support healthy body
composition and weight management. It is a botanical weight management
formula composed of Coleus forskohlii extract, Garcinia cambogia extract with
Garcinol and Piper nigrum extract. The composition of LeanGard® is aimed at
overcoming the shortcomings of the individual botanical ingredients, facilitating 1their actions and improved bioavailability to the target tissues and cells.
Helps to increase the lean body
mass
Decreases body fat accumulation
Stimulates the release of fatty acids
from the body fat for energy uptake
Provides antioxidant benefits
Supports satiety
Supports general fitness and overall
well-being
KEY BENEFITS
Each Capsule contains:
Ingredient
LeanGard® Blend
Quantity per Capsule
500 mg
Suggested use level: One Capsule twice daily
References:
1. A Prospective, Controlled, Randomized, Double Blind, Parallel-Group Study Comparing “The Efficacy and Safety of Oral Administration of LeanGard® Capsule with respect to Placebo for Twelve Weeks in Weight Management”. Sabinsa Study Report Protocol Number: CPL/09/LGD/MAR/07.
2. Conte A.A. A Non-Prescription Alternative in Weight Reduction Therapy. The Bariatrician. 1993: 17-19.
3. Conte A.A. The effects of (-) - Hydroxycitrate And Chromium (GTF) On Obesity. J Amer Coll Nutr.1994 (October);13 (5): 535 .
4. Katts GR, Pullin D, Parker LK, Keith PL, Keith S. Reduction Of Body Fat As A Function Of Taking A Dietary Supplement Containing Garcinia Cambogia Extract, Chromium Picolinate And L-Carnitine - A Double Blind Placebo Controlled Study. Abstract/Poster presented at a symposium on obesity organized by the Mexican Sociedad Medical del Sureste para el Estudio de la Obesidad, March 4, 1995, Merida, Yucatan, Mexico.
5. Badmaev V, Majeed M. Open Field, Physician Controlled, Clinical Evaluation Of Botanical Weight Loss Formula Citrin®. Nutracon 1995: Nutraceuticals, Dietary Supplements And Functional Foods. Day One (Sponsored by Global Business Research Ltd.). Published in the symposium proceedings.
6. Thom E. (-)Hydroxycitrate (HCA) In The Treatment Of Obesity. Int J Obesity. 20 (4): 75.
Each Tablet contains:
Ingredient
*
*
3Curcumin C Complex®
BioPerine®
Quantity per Tablet
525 mg
5mg
*Patented – US & International Patents
Weight Management
LeanGard®
Natural Bioprotectant
3Curcumin C Power™
Free radicals are highly reactive byproducts of biological processes in the body. Antioxidants neutralize free radicals in the body, and protect cells against the ravages of environmental and ingested toxins, that accelerate the aging process, and trigger inflammation, which is the root cause of chronic diseases.
A good quality natural antioxidant derived from dietary sources or in the form of supplements, provides anti-aging protection against degenerative diseases and helps to slow down the aging process of the skin, cells, tissues and organs. Our bodies produce their own antioxidants, but as we get older, the ability to produce antioxidants weakens.
The multifaceted benefits of antioxidant supplementation will be considerably useful, for people dealing with stress, dieters limiting their calories to 1,200 per day or less, people on a low-fat diet, smokers, older adults, and people with a family history of heart disease or cancer.
AntiOxidant is a proprietary blend of natural ingredients from Sami Direct that captures the combined benefits of powerful antioxidant molecules.
Inflammation is a natural response to injury, and triggers healing. However, uncontrolled inflammation is believed to be the underlying cause of chronic conditions including cardiovascular disease, various forms of cancer, metabolic syndrome, and obesity.
Supports a healthy immune system
and a balanced inflammatory
response
Not only scavenges free radicals, but
also prevents their formation
KEY BENEFITS
References:
1. Osawa,T. et al. (1995) Antioxidative activity of the tetrahydrocurcuminoids. Biosci. Biotechnol. Biochem. 59(9): 1609-12.
Dr. Peter Mitchell was awarded the 1978 Nobel Prize for Chemistry for his
discovery of the Chemiosmotic mechanism of ATP Synthesis which includes the
vital role of Coenzyme Q in the body’s energy systems.10
Coenzyme Q10
Coenzyme Q , abbreviated at times to CoQ is a 1, 4 - benzoquinone, where Q 10 10
refers to the quinone chemical group, and 10 refers to the number of isoprenyl
chemical subunits.
Coenzyme Q (CoQ ) is a compound found naturally in the energy-producing 10 10
center of the cell known as the mitochondria in most eukaryotic cells. CoQ is a 10
component of the electron transport chain and participates in aerobic cellular
respiration. It is involved in generating energy in the form of ATP (Adenosine
triphosphate). 95% of the human body’s energy is generated this way. Therefore,
those organs with the highest energy requirements—such as the heart, liver and
kidney – have the highest CoQ concentrations. It is logical to conclude that a 10
deficiency in coenzyme Q in any of the body's cells would affect cellular 10
functions, metabolic processes and energy generation.
Coenzyme Q supports cardiovascular functions, boosts energy metabolism, a 10
healthy immune system and the body’s natural healing processes.
Supports vitality and energy Level.
Supports a healthy immune system
and resistance to stress and
infections.
Supports improved exerc ise
tolerance and athletic performance.
Effects “beauty from within”
supporting healthy skin, hair and
nails.
Supports healthy ageing and
longevity.
Helps in prevention of loss of muscle
tone, when given as an adjunct
therapy alongwith cholesterol
lowering products.
CoQ Energizer™ is responsible for
95% of body’s Energy Production.
With ageing and other medication,
the CoQ Energizer™ level comes
down hence CoQ Energizer has to be
supplemented externally.
Assists in improving cardiac Health
& Heart related diseases.
Assists in treating male infertility
cases.
KEY BENEFITS
Each Softgel contains:
Ingredient
Coenzyme Q10
Vitamin E
BioPerine®*
Quantity per Softgel
60 mg
50 mg
2.5 mg
Suggested use level: One Softgel twice daily.
*Patented – US & International Patents
Each Softgel contains:
Ingredient
*
*
*
3Curcumin C Complex®
Tetrahydrocurcuminoids
Alpha tocopherol acetate
Selenium SeLECT® Pure
BioPerine®
Quantity per Softgel
50 mg
10 mg
25 mg
50 mcg
1 mg
Suggested Use :One softgel twice daily
*Patented – US & International Patents
Cellular Bio-energizer
CoQ Energizer™
Powerful Antioxidant
AntiOxidant