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Rehabilitation & return-to-play
after PRP injection for
lower limb tendinopathy
François Delvaux, PT, S&C, PhD
Jean-François Kaux, MD, PhD
University of Liege & SPORTS²/CHU Liege, Belgium
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Introduction – What’s PRP ?
• Centrifugation of autologous blood
• High concentration of platelets injected on the injury site
• Intention = to improve the healing process of the tissue
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Are PRP injections efficient for treating LL tendinopathies ?
Kearney 2021 JAMA
Boesen 2017 AJSM
Scott 2019 AJSM
Dragoo 2014 AJSM
de Jonge 2011 AJSM
de Vos 2011 BJSM
…
No strong evidence >< Promising results
But…
PRP are widely used in chronic tendinopathies & are not harmful; very often, physiotherapists receive patients after PRP
After a PRP injection, what kind of rehabilitation should the patient receive ?
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Literature search
PRPPlatelet-rich plasmaPlatelet concentrate
…
RehabilitationTreatment
PhysiotherapyExercise
…
(Nearly) no specific protocols
PRP & rehabilitation
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Experience&
reasoning
PRP and rehab: evidence is scarce!
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Consensus: Rehabilitation is essential after PRP injection
Is rehab essentiel after PRP injection?
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Time
Tendinopathy1st symptoms
PRPinjection
[..othertreatments failure…]
Load
[4-6 days]
Startrehab
Eccentric
Strength
Speed &power
Plyometrics &Specific to sport
[> 3 months]
[Small to very smallsteps]
Rehab after PRP injection : content
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Isolated sub-maximal eccentric contractions
• (3)-7*/week
• 1-2*/day
• 2-3 series of 15-30 reps
• Rest time = adapted
• Body weight
• Pain management
1st step : eccentric contractions
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Can eccentric contractions / exercises be painful?
Smith et al.BJSM 2017
Exercise & pain
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Smith et al.BJSM 2017
TendinopathyDuring exercises After exercises session
> 5/10
3-4/10
0-2/10
night and/or day after
No increase
temporary (few hours)
Exercise & pain
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• 3 sessions/week• 3-4 exercises/session• 3-4 series/exercise• Slow velocity• Rest intervals: long• 15RM 12RM 10RM 8RM 6RM• ≈ 70 ≈ 85% 1RM
Patellar tendinopathy Achilles tendinopathy
+ … + …
2nd step : improve strength
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(2-)3 sessions/week: o 1 session = strength (6-8RM)o (1-)2 sessions = speed & power
Speed Power
1. Flat ground• Soft hard ground• Progressively from ≈ 60%
to 100% of maximal speed• Importance of running technique
2. Decline ground
• 2-4 exercises/session
• 3-4 series/exercise
• Fast velocity
• Rest intervals: long
• 30 60% 1RM
• ≈ 6 reps/ex
3rd step : speed & power
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4th step : plyometrics & sport-specific
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• Personal history• Sport goals• Age• Physical fitness• …
30-40% = Sedentary people• Steps 1 & 2, steps 3 & 4• Very small steps progression• Importance of becoming active
Ex: Achilles tendinopathy
Individualised rehab
60-70% = Athlete• Steps (1) - 2 to 4• Small steps progression• Importance of load management before & after RTP
Importance to individualise rehab
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• Stretching
• US
• Deep transverse massage
• Osteopathy – manual therapy
• Taping
• Dry needling
• …
No high scientific evidence
Progressive loading is the main treatment
What about passive treatments ?
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• Rehabilitation programs after PRP injections for tendinopathy do not really differ
from usual tendinopathy rehabilitations
• The main objective = increase of tendon capacity progressive loading is the key treatment
• A progressive 4-stage rehabilitation continuum includes:
o Analytical progressive loading (eccentric)o Strength trainingo Speed and power trainingo Plyometrics and sport-specific training
• Pain management is a key component for every stage
• Rehabilitation content and progression have to be individualised
Conclusion