ASAHI NEO’S
Confidential / Internal Use Only
2Confidential / Internal Use Only
ASAHI NEO’SContents:
Property of ASAHI NEO’S PTCA Guidewire FamilyStructureCoating over the metal
Product Line-upComparison ASAHI NEO’S vs. ACS Products (structure/ performance)
Soft typeCTO typeSupport type and Others
Tip Stiffness Comparison
3Confidential / Internal Use Only
ASAHI NEO’SProperty of ASAHI NEO’S PTCA GUIDEWIRE Family ①
■ Structure
One-piece Core Wire
・High-strength stainless steel core wire.Unique taper design enables excellent torque response and steerability performance.
Jointless Spring Coil
・Our unique technology for jointless spring coil made of two different metals provides high torque response and good slides with devices.
4Confidential / Internal Use Only
ASAHI NEO’SProperty of ASAHI NEO’S PTCA GUIDEWIRE Family ②■ Coating over the metal
Medical grade silicon coating Fluororesin coating
Stable against various chemicals.Low friction.Good resistance against high and low temperature. Usable at a wide range of temperature.Chemically stable, elution-free against any materials which lead to the human body hazard. Superficially inactive. No negative influence to human tissue or blood.
Chemically stable, and highly bio-compatible with least bio-reaction.Heat and cold resistant. Less physical changes against heat. Durable against various sterilization methods.Specific superficial property. High water repellency, and less coagulation and sticking of blood.Low friction. (not as good as fluororesin but sufficiently lubricious)
5Confidential / Internal Use Only
ASAHI NEO’SASAHI NEO’S PTCA Guide Wire Line-up
Support
Flex
ibili
ty
More
MoreLess
LightAG145000Radio-opacity 3cmDiameter 0.014inchLength 175cm
Improved lubricity and good tip shape memory with our unique core design. Excellent torque response. This wire has a flexible tip and can be used as a first choice wire for almost all procedures.(Tip load 0.5G)
Flex
ibili
ty
Support
More
MoreLess
SoftAG141000Radio-opacity 3cmDiameter 0.014inchLength 175cm This is a first choice guidewire with high torque response and excellent
steerability because of the unique core property.(Tip load 0.7G)
Flex
ibili
ty
Support
More
MoreLess
IntermediateAG142000Radio-opacity 3cmDiameter 0.014inchLength 175cm This is a guidewire with a good balance of tip flexibility and support performance.
(Tip load 3.0G)
Flex
ibili
ty
Support
More
MoreLess
StandardAG143000Radio-opacity 3cmDiameter 0.014inchLength 175cm Improved tip stiffness with our unique core taper design.(Tip load 6.5G)
6Confidential / Internal Use Only
ASAHI NEO’SMiracle Series Applying the structure which further improves torque performance for CTO use.The tip part has the structure which is difficult to be trapped by the lesions.
Flex
ibili
ty
Support
More
MoreLess
Miracle3AG14M050Radio-opacity 11cmDiameter 0.014inchLength 175cm
(Tip load 3.0G)
Flex
ibili
ty
Support
More
MoreLess
Miracle4.5AG14M045Radio-opacity 11cmDiameter 0.014inchLength 175cm
(Tip load 4.5G)
Flex
ibili
ty
Support
More
MoreLess
Miracle6AG14M060Radio-opacity 11cmDiameter 0.014inchLength 175cm
(Tip load 6.0G)
Flex
ibili
ty
Support
More
MoreLow
Miracle12AG14M070Radio-opacity 11cmDiameter 0.014inchLength 175cm (Tip load 12.0G)
7Confidential / Internal Use Only
ASAHI NEO’S
Flex
ibili
ty
Support
More
MoreLess
This wire is developed for CTO use. Higher penetration ability than Miracles. Diameter of tip coil is tapered to 0.009 inch (φ0.23 mm). (Tip load 9.0G)
CONQUESTAG143090Radio-opacity 20cmDiameter 0.014inchLength 175cm
Flex
ibili
ty
Support
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MoreLess
Grand SlamAG141002Radio-opacity 4cmDiameter 0.014inchLength 175cm In spite of its flexible tip, the core is also designed to provide strong support when
approaching the tortuous lesions. (Tip load 0.7G)
Flex
ibili
ty
Support
More
MoreLess
Marker WireAG141010Radio-opacity 3cmDiameter 0.014inchLength 175cm
Same level of tip stiffness as SOFT. It has ten markers starting after 50 mm from the tip to scale lesions and position devices. (Tip load 0.7G)
Insert the proximalend of guidewireExtension
AG149000Diameter 0.014inchLength 150cm
The material of the inserting part( tube part) is Ni-Ti alloy.★Note: This wire has different connection structure from ACS DOC. ACS DOC cannot
be applied to ASAHI NEO’S.
8Confidential / Internal Use Only
A
Flexible tip by using shaping ribbon. (Tip load 0.4G)
ASAHI NEO’S Family H Family
Structural ComparisonASAHI NEO’S vs. A
Light
SoftB
C
D
Core-To-Tip structure. Its stiffness is middle between A andB.(Tip load 0.7G)
Flexible tip by using shaping ribbon.(Tip load 0.4G)
*先端荷重データは朝日インテック社測定値
ASAHI NEO’S( ASAHI INTECC Lab Test)
Improved lubricity and tip shape memory with our unique core design. Excellent torque response. This wire has the flexible tip and can be used as a first choice wire for almost all procedures.(Tip load 0.5G)
This is a first choice guidewire with high torque response and excellent steerability because of the unique core property.(Tip load 0.7G)
Higher support performance than B(Tip load 0.5G)
9Confidential / Internal Use Only
ASAHI NEO’S Performance ComparisonASAHI NEO’S vs.A ( ASAHI INTECC Lab Test)
0.7
0.50.4
0.50.4
0.0
0.2
0.4
0.6
0.8
1.0
SOFT LIGHT A B C
Tip load[gf]
Test Method
GW
■Tip Stiffness
10Confidential / Internal Use Only
ASAHI NEO’S■Torque Response Comparison (Soft type)
( ASAHI INTECC Lab Test)
090
180270360450540630720
0 90 180 270 360 450 540 630 720Rotational angle (°)
Dis
tal t
ip re
spon
se (°
)
Ideal Soft B A LIGHT C
R25R30R25 R25
Inner Dia.φ0.4mm L=300mm PE Tube
GW
Test Method
Proximal : Counter clockwise torque
11Confidential / Internal Use Only
ASAHI NEO’S■Tip Bent Resistance -Tip part- (Soft type)
0
0.1
0.2
0.3
0.4
0.5
0.6
50 60 70 80 90 100 110
Distance from tip (mm)
Ben
t Res
ista
nce
(gf・
C㎡
/cm
) A
B
Soft
Light
GW
Test Method
( ASAHI INTECC Lab Test)
12Confidential / Internal Use Only
ASAHI NEO’S Family H Family
CONQUEST
A
D
Structural ComparisonASAHI NEO’S vs. A (INT-CTO type)
This is a guidewire with a good balance of tip flexibility and support performance.(Tip load 3.0G)
Applying the structure which further improves torque performancefor CTO use. The tip part has the structure which is difficult to be trapped by the lesions. (Tip load 3.0G)
This wire is developed for CTO use. Diameter of tip coil is tapered to 0.009 inch (φ0.23 mm). (Tip load 9.0G)
( ASAHI INTECC Lab Test)
ASAHI NEO’S
Intermediate
Good controllability and torque response with Core-To-Tip Structure (Tip load 2.0G)
BMiracle 3
Suitable to CTO. High pushability and support performance (Tip load 5.0G)
CMiracle 6
(Tip load 6.0G) Improved trackability by its thicker distal core and longer taper length than H.(Tip load 8.0G)
For CTO use. Tip diameter is 0.010inch.(Tip load 3.5G)
13Confidential / Internal Use Only
ASAHI NEO’SPerformance Comparison
ASAHI NEO’S vs. A (CTO type)( ASAHI INTECC Lab Test)
4.56
12
98
53.5
0.0
2.0
4.0
6.0
8.0
10.0
12.0
Miracle 4.5 Miracle 6 Miracle12 Conquest A B C
■Tip stiffnessTip load
[gf]
Test Method
GW
14Confidential / Internal Use Only
090
180270360450540630720
0 90 180 270 360 450 540 630 720Rotational angle (°)
Dis
tal t
ip re
spon
se (°
)
Ideal Miracle 6 C Conquest
R25R30
R25 R25
Inner Dia.φ0.4mm L=300mmPE Tube
GW
Test Method
ASAHI NEO’S
Proximal : Counter clockwise torque( ASAHI INTECC Lab Test)
■Torque Response Comparison (CTO type)
15Confidential / Internal Use Only
ASAHI NEO’S■Tip Bent Resistance -Tip part- (CTO type)
0
0.1
0.2
0.3
0.4
0.5
50 60 70 80 90 100 110
Distance from tip (mm)
Ben
t res
ista
nce
(gf・
C㎡
/cm
) CONQUEST
C
Miracle 6
GW
Test Method
( ASAHI INTECC Lab Test)
16Confidential / Internal Use Only
ASAHI NEO’S■Trap Resistance -Load Test- (CTO type)
0 2,000 4,000 6,000 8,000 10,000 12,000Load (gf)
A
Miracle 3
Miracle 6
Miracle12
Test Method
GW Tip
( ASAHI INTECC Lab Test)
17Confidential / Internal Use Only
ASAHI NEO’S Family H Family
Structural ComparisonASAHI NEO’S vs. A (Support type and others)
Its core is designed to provide strong support when approaching the tortuous lesions. Comparing to S’Port, this wire is more flexible. (Tip load 0.7G)
・Same level of tip stiffness as SOFT. It has ten markers starting after 50 mm from the tip to scale lesions and position devices. ・Markers are soldered in the coil with same/ less outer diameter than the coil, so that the resistance against PTCA balloon catheter is small.・The coil with markers provide higher stiffness than SOFT, so that this wire can stretch the tortuous vessel and enables good support for device delivery.(Tip load 0.7G)
ASAHI NEO’S( ASAHI INTECC Lab Test)
AGrand Slam
HS is enabled by eliminating the middle coil and making the core diameter larger. This wire is suitable for delivering devices as DCA. (Tip load 0.7G)
Marker Wire
18Confidential / Internal Use Only
ASAHI NEO’S Performance ComparisonASAHI NEO’S vs. A (Support type) ( ASAHI INTECC Lab Test)
0.7 0.7
0.0
0.2
0.4
0.6
0.8
1.0
Grand Slam A
Tip load[gf] GW
■Tip Stiffness
19Confidential / Internal Use Only
ASAHI NEO’S■Tip Bent Resistance -Tip part- (Support type)
0
0.5
1
1.5
2
50 60 70 80 90 100 110Distance from tip (mm)
Ben
t res
ista
nce
(gf ・
C㎡
/cm
)
Grand Slam
A
GW
Test Method
( ASAHI INTECC Lab Test)
20Confidential / Internal Use Only
Guide Wire Tip Stiffness Comparison
GW
*ASAHI Lab Test Method
ASAHI NEO’S
ACS Floppy II, Balance 0.4G ASAHI NEO’S Light 0.5G ACS BMW 0.5G SciMed Choice Plus Floppy 0.6G ASAHI NEO’S Soft 0.7G ASAHI NEO’S Marker Wire 0.7G ASAHI NEO’S Grand Slam 0.7G ACS Traverse 0.7G ACS S’Port 0.7G Cordis Reflex Soft 0.8G Invatec Skipper Floppy 1.05G Invatec Skipper Floppy Support 1.1G ACS Intermediate 2.0G Invatec Skipper Intermediate 2.4G SciMed Platinum Plus 2.5G ASAHI NEO’S Miracle 3 3.0G ASAHI NEO’S Intermediate 3.0G Invatec Skipper Standard 3.4G ACS Cross-It 3.5G Terumo Cross Wire 4.0G ASAHI NEO’S Miracle 4.5 4.5G ACS Standard 5.0G ASAHI NEO’S Miracle 6 6.0G ASAHI NEO’S Standard 6.5G ACS Sting 8.0G ASAHI NEO’S Conquest 9.0G ASAHI NEO’S Miracle 12 12.0G
Pipe
Electronic Balance
10 mm
Test MethodBuckling load is defined as tip load.
(The distance from the lower end of the pipe to the upper side of the electronic balance is 10 mm.)
Tip loads of various guidewires