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Necrobacillosis
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Def : Infectious disease of animals caused
by Fusobacterium necroforum (Spheropherous necrophorum)
• Characterized by necrotizing lesions in the alimentary tract ,liver and respiratory system.
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Different conditions produced by the organism in different animals
In Cattle : liver necrosis Ulcerative rumenitis Ulcerative &necrotizing stomatitis and enteritis
Necrosis of tail , teat ,limbs and feet Foot rot (pododermatitis )
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Foot rot
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Necrobacillosis In calves Calf diphtheria Bronchopneumonia, purulent or
necrotic pneumonia and pleurisy Acute catarrhal, ulcerative or necrotic
enteritis Calf usually dies after 4-5 days due to
pneumonia and toxemia
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NecrobacillosisIn sheep Foot rot Lip and leg ulceration
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NecrobacillosisIn horse : Severe necrotizing disease of feet Gangrenous dermatitis ch’ch’ by
sharply demarcated necrosis. It is associated with fistulus withers ulcerative enteritis in foals
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Route of infection Secondary invasion following mucosal
damage or viral Ds.
( oral wound, trauma, eruption of teeth)
(predisposing causes)
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The organism invade the damaged mucosa and produce Endo&Exo toxins leading to Necrosis.
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Spread of infection within the infected animal :
Aspiration of necrotic material lung Gangrenous Pneumonia.
Ingestion of necrotic material Oesophagus Stomach Intestine necrotic enteritis
Emboli Circulation Necrotic lesions in different organs.
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Spread of infection within the infected animal :
Hepatic necrobacillosis observed in lambs and calves following omphalophlebitis or as a complication after ruminitis in cattle.
Infection of vagina and uterus after parturition as contamination after inflammatory genital diseases.
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Large well demarcated yellowish gray dry areas of necrosis surrounded by a hyperaemic zone on the tongue, gum, palate ,cheeks and pharynx.
Necrotic areas project above the mucosal surface Sloughs Deep ulcer
Diphtheric membrane of fibrinonecrotic exudate on the buccal mucosa , pharynx and larynx
Toe abscess and cellulitis may occur in sheep
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Structureless area of necrosis surrounded by hyperaemic zone and leucocytes,
later by thick capsule of granulation tissue
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Hepatic necrobacillosis
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Hepatic necrobacillosis
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Ch’ch’ by pseudomembrane formation (fibrinonecrotic exudate on the top of deep ulcers )
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