National Center for Foreign Animal and Zoonotic Disease Defense: Overview
Annual Meeting
Dr. Tammy Beckham Director June 27th, 2013
FAZD Center Mission To protect the nation’s
agriculture and public health sectors against high consequence foreign animal, emerging and/or zoonotic diseases Conducting Research Developing Technology Transitioning Products Training Workforce Communicating Results
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FAZD Center Reporting Structure
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Glen Laine Interim Vice President
for Research, Texas A&M University
Eleanor Green Dean, Texas A&M
College of Veterinary Medicine and
Biomedical Sciences
Mark Hussey Vice Chancellor and Dean of Agriculture
and Life Sciences, Texas A&M AgriLife
Craig Nessler, Director, Texas A&M
AgriLife Research
Tammy Beckham Director, FAZD Center
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Education & Outreach Theme Leader
HEATHER SIMMONS
Assistant Director for Finance VIC SEIDEL
Information Analysis Systems Theme Leader
JAMES WALL
Business Coordinator
CHRIS SCARMADO
FAZD Staff
Leveraged TAMUS Appointments
Director TAMMY BECKHAM
Associate Director MELISSA BERQUIST
Program Coordinator
KELLY SOLTYSIAK
Chief of Staff STACY MORRIS
Communications Manager
RUSTY CAWLEY
Program Assistant RACHEL WHISENANT
Administrative Assistant
LANITA JACKSON
Program Coordinator SHARON ALDERETE
155 partners in 42 U.S. states …
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Alabama • Auburn Univ. • Alabama Dept. of Agriculture and Industries • Cooperative Extension Arizona • Arizona Dept. of Agricultural Resources Arkansas • Cooperative Extension • Arkansas Dept. of Agricultural Education • Arkansas Veterinary Medical Assoc. California • IntegenX • Univ. of California- Davis • California Dept. of Food and Ag • UCLA • California Polytechnic State Univ. • Lawrence Livermore National Laboratory • Cooperative Extension Connecticut • Univ. of Connecticut • Cooperative Extension • Connecticut Dept. of Agriculture Colorado • Colorado Dept. of Agriculture • Cooperative Extension • Colorado State University • USDA Centers for Epidemiology and Animal Health (CEAH)
District of Columbia •USDA National Institute of Food and Agriculture (NIFA) Florida • Florida Dept. of Ag Education • Florida Veterinary Medical Assoc. • Florida A&M Univ. • Univ. of Florida Georgia • Georgia Dept. of Agriculture • Cooperative Extension • Merial, Ltd. • Univ. of Georgia • Centers for Disease Control and Prevention (CDC) Idaho • Idaho State Dept. of Agriculture • Cooperative Extension Indiana •Indiana Board of Animal Health • Cooperative Extension Iowa • Iowa State Univ. • Iowa Dept. of Agriculture and Land Stewardship • National Pork Board • USDA National Veterinary Services Laboratories • Center for Food Security and Public Health • MetaFarms • Elite Pork • GlobalVetLINK
Kansas • Kansas State Univ. • Center of Excellence for Emerging and Zoonotic Animal Diseases (CEEZAD) • National Agricultural Biosecurity Center • Cooperative Extension Kentucky • Kentucky Dept. of Agriculture • Cooperative Extension Louisiana • Cooperative Extension • Louisiana Dept. of Agriculture and Forestry Maine • Univ. of Maine • Maine Dept. of Agriculture • Maine Compost School • Maine Dept. of Environmental Protection • Cooperative Extension • University of New England Maryland • Cooperative Extension • Maryland Dept. of Agriculture and Rural Development • Joint Pathology Center Massachusetts • Massachusetts Dept. of Agriculture Michigan • Michigan Dept. of Agriculture • Michigan State Univ. • Cooperative Extension
Minnesota • Univ. of Minnesota • Cooperative Extension • National Center for Food Protection and Defense (NCFPD) Mississippi • Mississippi Dept. of Agriculture and Commerce • Mississippi Board of Animal Health • Cooperative Extension • Jackson State Univ. Missouri • Univ. of Missouri • Cooperative Extension • Missouri Dept. of Agriculture Montana • Montana State Univ. • Montana Dept. of Livestock Nebraska • Univ. of Nebraska- Lincoln • Nebraska Dept. of Agriculture • Cooperative Extension New Hampshire • New Hampshire Board of Veterinary Medicine • Cooperative Extension • New Hampshire Dept. of Agriculture, Markets & Food New Jersey • New Jersey Dept. of Agriculture • Cooperative Extension
… the District of Columbia and 14 foreign nations
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New Mexico • New Mexico Dept. of Ag Education • Cooperative Extension • New Mexico Dept. of Agriculture • New Mexico State Univ. New York • Cornell Univ. • New York Dept. of Ag and Markets • Plum Island Animal Disease Center • TetraGenetics, Inc. • Cooperative Extension North Carolina • North Carolina Dept. of Agriculture and Consumer Services • North Carolina Farm Bureau • Smithfield Premium Genetics Group • Cooperative Extension Ohio • Ohio Dept. of Ag Education Oklahoma • Cooperative Extension Pennsylvania • Cooperative Extension • Univ. of Pennsylvania Rhode Island • Rhode Island Dept. of Environmental Management South Carolina • South Carolina Dept. of Agriculture Tennessee • Tennessee Dept. of Agriculture
Texas • BIOO Scientific Corp. • Borlaug Institute • Caliber Biotherapeutics • Sanderson Farms • Texas A&M AgriLife Extension • Texas A&M AgriLife Research • Texas A&M Univ. • Texas A&M Veterinary Medical Diagnostic Laboratory • Texas Animal Health Commission • Texas Center for Applied Technology • Texas Veterinary Medical Assoc. • Univ. of Texas Medical Branch Utah • Cooperative Extension Vermont • Vermont Agency of Agriculture, Food, and Markets • Cooperative Extension Virginia • Ceres Nanosciences • George Mason Univ. • Virginia Dept. Of Agriculture and Consumer Services • Virginia Dept. of Environmental Quality • National Renderers Association Washington • VMRD, Inc. • Micronics, Inc. West Virginia • West Virginia Dept. of Agriculture
Wisconsin • Univ. of Wisconsin- Madison • Wisconsin Veterinary Diagnostic Lab Wyoming • Cooperative Extension • Wyoming Livestock Board • Univ. of Wyoming Plus: USDA National Animal Health Laboratory Network (NAHLN) laboratories in 43 states and EDEN (Extension Disaster Education Network) International partners Australia • Elizabeth Macarthur Agricultural Institute Bangladesh • Chittagong Veterinary and Animal Science Univ. Belguim • CODA-CERVA • Okapi Sciences Canada •Canadian Food Inspection Agency •Manitoba Dept. of Agriculture •Nova Scotia Agricultural College •Government of Alberta Egypt • Government Veterinary Service Kazakhstan •Kazakhstan National Vet Laboratory
Kenya • Ministry of Livestock Pakistan • Pakistan National Vet Laboratory • National Univ. for Science and Technology Tanzania • Sokoine Univ. (Arusha) • Ministry of Livestock and Fisheries Development (Dar es Salaam) Thailand • Chulalongkorn Univ. Turkmenistan • Ministry of Agriculture Uganda • Makerere Univ. • National Agricultural Research Organization (NARO) United Kingdom • The Pirbright Institute • Forsite Diagnostics, Inc. Ukraine • State and Scientific Research Institute • Institute of Veterinary Medicine • Institute of Experimental and Clinical
Veterinary Medicine • Bilia Tservka National Agraran University • Regional Diagnostic Laboratories of Veterinary Medicine • State Veterinary Services and Phytosanitary Service of the Ukraine • National Academy of Agrarian Science
Customers and Stakeholders
Industry
• Agricultural & allied Industries
• Bio-pharmaceutical • Transportation
DHS
• Science and Technology Directorate
• Office of Health Affairs • Plum Island Animal
Disease Center • Office of Infrastructure
Protection • Transportation Security
Administration • Customs and Border
Protection • Other DHS entities
USDA
• Animal and Plant Health Inspection Service (APHIS)
•National Veterinary Services Labs •Foreign Animal Disease
Diagnostic Laboratory •National Animal Health
Laboratory Network •Centers for Epidemiology and Animal Health
•NCAHEM •National Veterinary Stockpile
• Agricultural Research Service (ARS)
• National Institute of Food and Agriculture
• Foreign Agricultural Service
Other Fed/State Agencies
• Health and Human Services • Centers for Disease
Control and Prevention • State animal health
officials • Federal Bureau of
Investigation • Intelligence community • Emergency responders • Department of Defense •Defense Threat Reduction Agency (DTRA)
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Principal and Co-Principal Investigators
• Alfonso Clavijo • Garry Adams • Don King • Satya Parida • Mangkey
Bounpheng • Bob Rowland • Mike Hogan • Ben Lepene • John Gerdes • Scott Adams • Adam Zelma • Brian Bird • Lance Ford • Ute Stroeher
• Jim Wall • Mike Sanderson • Keith Biggers • Lindsey Holmstrom • Amy Delgado • Tom Hairgrove • John Wenzel • Nick Streigel • Keith Roehr • Marianne Ash • Jim Roth • Claire Andreasen • Kevan Flaming
• Andy Vestal • Dale Rozeboom • Heather Simmons • Buddy Faries • Clay Ashley • Raghavasan Srinivasan • Amy Swinford • Ken Burton • Craig Beardsley • Mike McWhorter • Derek Mosier • Andy Schwartz • Steve Weber • Walt Cook • Matt Erdmann • Don Davis • Lindsey Holmstrom • Terry Hensley • Bruce Williams • Sandra Lovering
Biological Systems Information & Analysis Systems
Education & Outreach
• Blanca Lupiani • Lance Ford • Youngqun He • Jorge Osorio • Waithaka Mwangi • Barry Holtz • Kathy Kurth • Linda Dixon • Stuart Nichol • Kylene Kehn-Hall • Chungwon Chung • Pam Ferro • Sandy Rogers • David Lefebvre
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Core Alignments/Partnerships
Industry
PIADC
DHS S&T
CEEZAD
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Programmatic Guidance
FAZD Management
Federal Partners
External Advisory
Committee Industry Partners
Internal Advisory
Committee
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Programmatic Guidance
OUP Program Management National Guidance Documents Homeland Security Presidential Directives Protecting Against High Consequence
Animal Diseases: R&D Plan National Workshops Agricultural Screening Tools Workshops Criteria for the Transition of FAD-Related
Models to Use in Decision Making Border Protection Against FADs: Gap
Analysis
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Programmatic Guidance
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Annual Meeting Stakeholder input, review of all projects
Annual External Advisory Committee Meeting Held in coordination with annual meeting
Midterm Review (January 2013) External review panels (REAP) 4 reviewers per proposal: 3 SMEs and industry representative
Overview: 2013 in Review
State of the Center 2013 Accomplishments/Highlights Future: 2014 Program Value of Centers of Excellence Today’s Agenda
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FAZD Center: Approach Enhance and evolve partnerships Identify best approaches and cutting edge
technologies Focused portfolio (basic and applied)
Aligned with national needs and identified gaps Coordinated with DHS S&T and USDA Coordinated with industry (ag and pharma) partners Competed through Request for Proposals (RFP) and
peer review Transition innovative products to end-user
Engage customers, partners, commercial sector throughout project performance
“To ensure FAZD Center products are on target and
utilized to enhance agricultural resiliency-To make a difference”
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FAZD Center: Approach
Research Portfolio Balanced portfolio Basic and applied research Emphasis on delivery/transition of
products/engagement of end-user Simultaneous development of ConOps and policy to
ensure transition
Accountability focused; target for on-time delivery within the projects
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Resiliency
Surveillance & Detection
Response & Recovery
Education &
Outreach
Prevention & Preparedness
Partnerships
Agricultural Screening Tools
Educating the Next Generation
Workforce
Emergency Preparedness and Response
Strengthening Ag Preparedness
PIADC FAZD
International Partners
Ag/Allied Industry Biopharma
Industry
DHS S&T/ OHA
USDA APHIS &
ARS
CEEZAD
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Innovative Technology Transition
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Research Portfolio
• National priorities • WH directives • OUP guidance • Gap analysis • Industry • Workshops/conferences • FAS SCC/GCC
Execute
• Regular reporting/project management • Ensure partnerships/
communication • Create/maintain necessary
linkages • Performance indicators • “Go/no go decision”
RFP
• Alignment with national needs SME/industry review
• Partnerships needed for successful transition? Transition plan clearly defined?
• Impact: “so what?” factor
Transition Delivery
• Product to end-user • Pilots where appropriate • Full scale implementation • Ensure policies and
procedures in place for implementation
•
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Integrated Portfolio
Biological Systems •Agricultural screening tools
•Penside diagnostics •DIVA assay •Sample optimization
•Reagents/monoclonals •Vaccines
•African Swine Fever •Classical Swine Fever-surge technology
•FMD anti-virals
Information Analysis •Ag Connect-information
dashboard framework • E2E: Business continuity • Enhanced Passive
Surveillance • Emergency Response Support
System • Laboratory Capacity
Estimation Model
Education & Outreach •Veterinary Science Program •Support for business continuity
planning; FASTEggs •DHS career development grants •3D Symposium •NIFA career development URF •International portfolio
Domestic & International Partnerships •Workshops/conferences
•AST workshops, NPB, 3D •Linking partners •Ensuring policies and procedures
in place to implement tools •Visiting scientists
Biologics: Vaccines, Diagnostics, and Screening Tools
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BIO Overview
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• Transition/delivery focused portfolio • Projects selected address national, high priority
gaps • Strong partnerships with USDA and DHS ensure
project relevance and transition potential • Currently, 15 research projects involving
industry, academic, and government partners • Vaccine development program focused on
development of novel platforms & technologies to identify vaccine candidates
• Agricultural screening tools program supports business continuity planning and integrates with IAS and EOS portfolios
ASF Vaccine
Validated, Licensed Kits Immunomodulators
Reagents Development Sample Prep/Transport
Ag Screening Tools
RESEARCH PORTFOLIO
Programmatic Areas of BIO Portfolio
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Biologics: Vaccines Vaccines Vaccines for transboundary diseases Rift Valley Fever (RVF) vaccine and complimentary cELISA
CDC-Deltamune Pty. Ltd. (South Africa) DIVA ELISA-FAZD partnership
African Swine Fever (ASF)-Reverse vaccinology DHS S&T HSARPA funded project
Plant-based technology for CSF Nicotiana benthamiana plant-based expression DHS OUP funded project Animal health partner, Caliber Biotherapeutics, TAMU CVM
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Defining the Needs and Requirements for Agricultural Screening Tools (Nov 2010)
Agricultural Industry Perspective of Utilizing Agricultural Screening Tools (April 2011)
Recommendations for Establishing Policies and Concepts of Operations for Use of Agricultural Screening Tools (Oct 2011)
Policies and Concept of Operations Recommendations for the Use of Agricultural Screening Tools (May 2012)
Workshops to Coordinate and Enhance the Agro-Security Enterprise
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Biologics: Diagnostics/Screening Tools Diagnostics Serological and nucleic acid detection technologies Useful for determining herd status and supporting trade
activities Work with national and international partners to develop
and validate internationally recognized assays FMD 3B ELISA for differentiating vaccinated vs. infected animals FMD bulk tank milk PCR assay Penside diagnostics
LAMP assay for FMD PanNAT penside assay (real time PCR) Serological assay for RVF
Production and characterization of RVF monoclonal reagents Evaluation of ASF diagnostic PCR assay with novel/pooled samples
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FAZD Center Highlights/Impacts- (BIO)
Agricultural Screening Tools program Diverse group of agents/targets
FMD, RVF, ASF, CSF, PRRS, endemics Highlights:
3B DIVA FMD ELISA assay Collaboration with USDA ARS, USDA APHIS,
DHS S&T (Plum Island), Pirbright & VMRD, Inc. Pilot ELISA kit evaluated during phase I Disclosure filed on 3B monoclonal antibody
Bulk tank milk assay NAHLN laboratories, PIADC APHIS, Pirbright,
FAZD Negative cohort testing in NAHLN completed Dossier for review by NAHLN technical
methods working group summer 2013
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Year 4 Proposed BIO projects
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Project Title Lead PI Partners
Antiviral therapy for the containment of foot-and-mouth disease virus outbreaks
David Lefebvre CODA-CERVA, University of Leuven, Okapi Sciences
Universal sample preparation tool for the concentration, enrichment and detection of Rift Valley Fever viral proteins
Ben Lepene Ceres Nanosciences, George Mason University
Validation and Transition of a 3B FMDV Competitive ELISA Kit and Transition to the National Animal Health Laboratory Network
Mangkey Bounpheng TVMDL, Pirbright Institute, USDA FADDL, VMRD
Performance Evaluation and Validation of a FMDV 3B Competitive ELISA for Detection of FMDV Infection in Swine
Mangkey Bounpheng TVMDL, Pirbright Institute, VMRD
The Matrix-Chaperone: Ambient Temperature Biospecimen Collection, Transport and Banking, For Simplified Animal Disease Screening (Phase II)
Pam Ferro TVMDL, IntegenX, TAMU CVM
Development and Evaluation of a Multi-Species Competitive ELISA for the Detection of Antibodies to Rift Valley Fever Virus
Sandy Rogers TVMDL, TAMU CVM, VMRD
Develop a 3B-FMDV cELISA Diagnostic Kit
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Leverages initial OUP investment -3B monoclonal antibody
Supports FMD “vaccinate-to-live” policy Strong industry/government/academic/international
collaboration Kit utilizes USDA ARS developed antigen with FAZD
developed antibody Testing of serum samples from infected and vaccinated
cattle at the Pirbright Institute and USDA APHIS FADDL Testing of FMDV positive wildlife and SAT+ cattle samples
at USDA ARS Small scale negative cohort testing at TVMDL
Develop a 3B-FMDV cELISA Diagnostic Kit
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Investment from OUP in FMDV monoclonal antibody development
Evaluation and selection of best monoclonal and antigen
Delivery of v2.0 FMDV ELISA pilot kits to DHS
June 2010 December 2013
Kit development, bench validation, and performance improvement
FAZD DHS/S&T DHS OUP
TVMDL, BIOO USDA ARS/APHIS VMRD, Inc End user
Validation in swine
Transition to NAHLN
September 2014 September 2014
Develop a 3B-FMDV cELISA Diagnostic Kit: Outcomes No import permit required More rapid response with US-based manufacturing
Lower cost and faster results cELISA results obtained in hours rather than days
DIVA compatible with newly licensed DHS-Ad5 vaccine Distinguish vaccinated from infected animals
Improved performance over “gold standard” cELISA detects all seven FMDV serotypes 99.8% diagnostic specificity; 100% diagnostic
sensitivity
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Antiviral Therapy for the Containment of Foot and Mouth Disease Virus Outbreaks Proposed in Y4 (FY2013) OUP Workplan Identification and testing of novel antiviral compounds
using small animal models Provide pan-serotypic antiviral activity for interim
protection prior to onset of immunity after vaccination Lead candidate identification, pharmacokinetic and safety
studies, and proof of concept demonstration
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Partners: CODA-CERVA (Belgium) and Okapi Sciences
Information & Analysis
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FAZD Center Highlights/Impacts-(IAS) Information Dashboard Framework (IDF) Leveraged investment in Biosurveillance
Common Operating Picture (BCOP) Initial OUP and DHS S&T investment Expanded scope for IDF utilization IDF customized for:
laboratory capacity incident command business continuity surveillance
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Biosurveillance Emergency Response Laboratory Capacity Business Continuity
• USDA CEAH/NSU • SAHOs • Practitioners • Producers • State epi
• USDA NCAHEM • AVICs • SAHOs
• USDA NAHLN • Diagnostic labs • USDA NCAHEM
• AVICs • SAHOs • Producers
PERSPECTIVES
USERS
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Engage to Excel (E2E)
Cornerstone of FAZD Center research for FY2012-FY2014 Focused on national scale priority; protecting
agricultural infrastructure-high impact Supporting business continuity during animal disease
outbreak Mitigating disruption to normal business cycle for
livestock and products Enhancing resiliency
Engage potential customers early in the development process and coordinate throughout transition to ensure that research results meet user requirements
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FAZD Center Highlights/Impacts- (IAS) AgConnect: maintaining business continuity-E2E Supports managed movement during disease outbreak Enhanced data integration and visualization capabilities for
secure commodity supply plans Secure Pork Supply
Supporting data management and integration Agreement established with major swine producer and data management company Pilot project; demonstration in February 2013 and July 2013
Utilization of AgConnect framework for integrating and visualization of producer data (movement; biosecurity; and diagnostic)
Secure Milk Supply Collaboration with 6 New England states and dairy industry Data collection and integration tools to support NE SMS
Building agricultural resiliency through support of business continuity planning
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Proof-of-Concept Demonstration Producer (Private Company) Testing Results (Diag. Lab) Premises (SCS)
State Premises and Plant
Data
Testing Results
Producer Census and Movement
Data
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IAS Successes: Engage to Excel Proof of concept system focused on integrating
data streams from a single industry, state, and producer Integration of premises and plant data from SAHO
office Census and movement data Diagnostic test order and test result data from State
VDL Illustrates the overall data-sharing concept, and
incorporates different visualization and analytical tools for working with integrated data
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Enhanced Passive Surveillance (EPS) Pilot Projects
Proof-of-concept studies designed to demonstrate the usefulness of multiple-data stream syndromic surveillance by: Applying the power of real-time reporting
and data aggregation to animal and wildlife surveillance Leveraging first responders (veterinarians)
for animal and public health surveillance Estimating baseline prevalence rates of
observed animal health anomalies for each stream
Evaluating the significance of resulting signals as disease detection events
Providing early warning information obtained from validated signaling activity to stakeholders to assist in making decisions
DHS HSARPA & USDA funded projects Cattle & Small Ruminants Equine & Poultry
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Enhanced Passive Surveillance (EPS) System
Biosurveillance Field Entry System (BFES) • iPad application and web-based reporting tools • Allows for the collection and analysis of syndromic surveillance data • Offers a mobile application for individuals to input information about a
symptomatic animal from within a clinical setting or from the field
Enhanced Passive Surveillance (EPS) Analyst Workstation • Provides epidemiologists and analysts with the capability to aggregate
and analyze the collected data through the use of various visual, geospatial, and temporal analysis tools
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Seven Syndromes • CNS/ Musculoskeletal • Digestive • Respiratory • Reproductive/Abortion • Sudden Death • Toxicity • Vesicular
EPS Analyst Workstation
BFES iPad app
IAS Successes: EPS Successfully integrated four data streams into analyst
workstation Markets, Pre-order VDL data, post-test result data, veterinary
practitioners, wildlife Built and implemented an expandable system capable of
collecting, integrating, analyzing, sharing, and protecting animal health surveillance data
Users engaged, nearly 100% reporting from field veterinarians Incentives for users built into as identified iCVI, business solutions, practice notes (medical records)
Successfully built in algorithms to allow for baseline calculations Increased interest from national industries/organizations for
participation 40
Year 4 Proposed IAS Project Engage to Excel: Maintaining Business
Continuity and Performing Risk Management during an Animal Disease Outbreak Build on first spiral of development
Expand the concept in complexity (incorporating interstate movement and program diseases) and participation (enrolling additional producers and states)
Integrate with USAHerds database Pilot in 3 states (Indiana, Colorado, & Iowa)
Obtain requirements/feedback Leverage ongoing work with Enhanced Passive Surveillance Project
iCVI, Global Vet Link partnership
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Education & Outreach
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FAZD Center: Impacts (EOS) K-12 programming provides outreach to over
5,400 students (~220 schools) in six states and over 300 High School Agriculture and 4-H Extension personnel trained or in program on an annual basis
Approximately 250 graduate students have matriculated through FAZD Center since 2004
More than 1,200 individuals have been trained on activation and use of the Animal Health Network in 21 states since inception
194 users in 67 labs (~85% of users trained) work with the Laboratory Capacity Estimation Model
41 users trained in the Biosurveillance Field Entry System
Approximately 68 partners in 24 states and 7 international
countries.
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FAZD Center Education & Outreach Nationwide transition of two programs Animal Health Network Youth career-oriented educational program for the
veterinary paraprofessional 265 students matriculated since 2004 through Career
Development Program and FAZD funded projects Success in building partnerships and competing for
external funding International training program Expansion of international training program/development Epidemiology & diagnostics
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Core Components: Career Development Program
Veterinary Science Certificate Program
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FAZD Center Veterinary Science Certificate Program
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Certificate program that contains 150
lessons and 500 apprenticeship hours Targets paraprofessionals in
Clinical veterinary medicine Laboratory science and technology One health science and technology
Utilized in the Caribbean for independent
study.
Independent study, instructor facilitated, or e-learning environment
Flagship EOS Program for veterinary
paraprofessionals
International Capacity Building and Training
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International Capacity Building Activities PK-LIMS project Partners: UN FAO, USDA-FAS,
TAMUS, FAZD Ensure information flow between
provincial and national laboratories and complement ongoing FAO FMD control program efforts in country
Scientific Exchanges Partners: TVMDL, Borlaug Institute,
TAMU CVM, NVSL, USDA CEAH Epidemiology & diagnostics Kazakhstan, East Africa, Turkmenistan,
Ukraine, Egypt
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Development and Implementation of a Laboratory Information Management System and Biosurveillance Program for Foot-and-Mouth Disease in Pakistani Veterinary Diagnostic Laboratories
Research with
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Collaboration with Borlaug Institute, TAHC, NVSL, CEAH, TVMDL, and USDA APHIS VS
Goals To obtain more information about epidemiological
studies and surveillance To gain access to the latest technology in diagnostic
and analytical epidemiology To know more about brucellosis and tuberculosis
control and eradication policies in the U.S. To apply biosecurity and biosafety measures To learn more about specific testing used in control
programs for brucellosis and tuberculosis
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International Program Capacity Building and Training with Egypt
Fall 2012
Collaboration with Borlaug Institute, TAMU CVM, TVMDL, TAHD, CEAH, NVSL, University of Wyoming
Goals Development of surveillance and monitoring systems Enhance knowledge in laboratory methods for brucellosis Enhance knowledge of latest research capabilities for
brucellosis
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International Program Capacity Building and Training with Kenya, Uganda, and Tanzania
Spring 2013
Education & Outreach Year 4 Veterinary Science Program expansion
State adoption-expanding in 5 states E-learning materials
Career Development Grant Integration with ongoing AgConnect projects
Develop training manuals/training courses International Training opportunities
Borlaug Institute USDA FAS
Modeling Validation Workshops Identify criteria for FAD-related models Develop adapted “model readiness levels” for
model transition Identify acceptability criteria
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Future Direction International portfolio expansion Recommendation from FAZD EAC Establish partnerships for joint research efforts Study diseases where they occur Access to samples for validation, development
Leverage OUP funding to expand funding base for Center Explore additional sources of funding to include private
partnerships Continue to build partnerships, collaborations and
enhance One Health activities HHS, CDC, DOD
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Future Direction
Pilot AgConnect suite of tools Evaluate and build private partnerships in context
of AgConnect Work with industry partners to enhance day-to-
day uses for AgConnect suite Pilot AgConnect tool with SAHO and industry Customization of tool and valuable feedback; setting
requirements Determine transition strategy for AgConnect
components/suite of tools
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Bringing together diverse, multi-disciplinary set of partners to address the complex challenges facing our agricultural and public health sectors
Linking customer bases to allow for common solutions to national challenges Agricultural Screening Tools (AST) Workshops Border Protection Against FADs: Gap Analysis
Workshop National Pork Board FAD Strategic
Planning Session
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FAZD Center: Value Added
Identifying best approaches and cutting edge technologies that can be adapted for use in this mission space, and transition them into use 3B DIVA FMD ELISA: new diagnostic tool is DIVA
compatible with newly licensed FMD adenoviral vaccine AgConnect: versatility of tool to
enhance Ag Resilience/Preparedness
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FAZD Center: Value Added
Identifying and leading local, regional and national scale pilots for new emerging technologies 3B DIVA FMD ELISA Bulk tank milk FMD assay Laboratory Capacity Estimation
Model Business Continuity (E2E) Secure Pork
Plan Enhanced Passive Surveillance
Program
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FAZD Center: Value Added
Work closely with state and national agricultural commodities, producers and veterinarians to ensure technologies and solutions are on target and will result in a product that enhances resiliency within this sector Ag Screening Tools AgConnect Educational and outreach tools
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FAZD Center: Value Added
The Agricultural Enterprise
http://fazd.tamu.edu
QUESTIONS?
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FAZD Center Program Vaccine and Diagnostic Development Agricultural Screening Tools Novel sample preparation technologies AgConnect: Overview, E2E Enhanced Passive Surveillance Veterinary Science Program Panel: Partnerships
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