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Nanomedicines
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Nanomedicines for diagnosis and therapy
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Materials for nano-medicines
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Importance of nanomedicine for cancer treatments
RES: An older term for the mononuclear phagocyte system
- A part of the immune system that consists of the phagocytic cells located in reticular connective tissue. - The cells are primarily monocytes and macrophages, and they accumulate in lymph nodes and the spleen.
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Nano-carriers for drug delivery
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Liposomes
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Advantages of liposome structure
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Polysomes
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Polymeric micells
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Amphiphilic polymers for micells
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Advantage of polymeric micells
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Drug release from polymeric micells
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Other types of polymeric micells
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Dendrimers
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Advantages of dendrimers
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Hydrogel nanoparticles
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Stealth effect of PEGs
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Doxorubicine-EG-Folate modified micells
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Doxorubicin
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Liposome products
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Angiogenesis in cancers
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ERP (Enhanced permeability and retention) effect
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Leaky blood vessels in tumors
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Passive tumor targeting by EPR effect
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Tumor targeting in nano-medicines
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Barriers in in-vivo implementation
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Lipid emulsion