www.ebmt.org #EBMT16
EBMT database 2016: transplants by disease category
NRM (%) by period according to the intensity of the
conditioning regimen
Allo-SCT 18-50 yo – NRM (%) by period
0
20000
40000
60000
80000
100000
120000
140000
139249
Multiple Myeloma Lymphoma Acute Leukemia Solid Tumor
Chronic Leukemia MDS & MPN Bone Marrow Failure Inherited Disorder
Hemoglobinopathy Autoimmune Disease Histiocytic Disorder
0%
5%
10%
15%
20%
25%
30%
35%
100d NRM 6 m NRM 12 m NRM
1994-1998 1999-2003 2004-2008 2009-2013
0%
5%
10%
15%
20%
25%
100d 6 m 12 m
1999-2003 2004-2008 2009-2013
0%
5%
10%
15%
20%
25%
100d 6 m 12 m
1999-2003 2004-2008 2009-2013
RIC MAC
0%
10%
20%
30%
40%
50%
60%
70%
80%
90%
100%
2000 2001 2002 2003 2004 2205 2006 2007 2008 2009 2010 2011 2012 2013
BEAM CBV Thiotepa TBI
Conditioning regimens for lymphomas in the ASCT setting
Transplant activity for lymphoma EBMT 2001-2012
0
20
40
60
80
100
120
140
160
180
200
0
200
400
600
800
1000
1200
1400
1600
1800
2000
auto
allo
Absolute numbers 2012 % increase 2001 -> 2011
CLL HL TCL DLCL FL MCL
DLCL HL MCL TCL FL CLL
Total lymphoma transplants 2012 (w/o CLL): allo 1427; auto 6177
-100
-50
0
50
100
150
0%
50%
100%
2000 2002 2004 2006 2008 2010 2012
BEAM CBV Thiotepa TBI
0%
50%
100%
2000 2002 2004 2006 2008 2010 2012
BEAM CBV Thiotepa TBI
DLBCL
0%
50%
100%
2000 2002 2004 2006 2008 2010 2012
BEAM CBV Thiotepa TBI
FL
0%
50%
100%
2000 2002 2004 2006 2008 2010 2012
BEAM CBV Thiotepa TBI
MCL
HL HL+DBBCL+FL+MCL
0
50
100
150
200
250
300
350
400
450
TCL FL CLL HL DLCL MCL
Members and staff: Peter Dreger (Chair), Stephen Robinson (Secretary), Olivier
Hermine, Silvia Montoto, Norbert Schmitz, Harry Schouten, Anna Sureda, Alina
Tanase, Ariane Boumendil (Statistician), Hervé Finel (Study Coordinator)
General activity
Lymphoma Working Party