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Losartan

For more information on our products custom synthesis, contact SynZeal today.

standards@synzeal.com www.synzeal.com

SZ-L028001

Losartan Potassium

124750-99-8

C22H22CIKN6OK

461.0

SZ-L028002

Losartan EP Impurity A

79047-41-9

C8H13ClN2O

188.7

SZ-L028003

Losartan EP Impurity B

160514-13-6

C14H12N4O

252.3

SZ-L028004

Losartan EP Impurity C

860644-28-6

C22H23ClN6O

422.9

SZ-L028005

Losartan EP Impurity D

83857-96-9

C8H11ClN2O

186.6

SZ-L028006

Losartan EP Impurity E

120568-11-8

C14H12N4

236.3

SZ-L028007

Losartan EP Impurity F

1332713-64-0

C25H29ClN6O

465.0

SZ-L028008

Losartan EP Impurity G

76-84-6

C19H16O

260.3

SZ-L028009

Losartan EP Impurity H

133909-99-6

C41H37ClN6O

665.2

SZ-L028010

Losartan EP Impurity I

1006062-28-7

C41H37ClN6O

665.2

SZ-L028011

Losartan EP Impurity J

1006062-27-6

C24H25ClN6O2

465.0

SZ-L028012

Losartan EP Impurity K

114798-36-6

C22H21ClN6O

420.9

SZ-L028013

Losartan EP Impurity L

230971-71-8

C44H44Cl2N12O

827.8

SZ-L028014

Losartan EP Impurity M

230971-72-9

C44H44Cl2N12O

827.8

SZ-L028015

Losartan Hydroxy N2-Trityl Impurity

154709-18-9

C33H26N4O

494.6

SZ-L028016

Losartan Isomer N2-Trityl Impurity

150098-04-7

C41H37ClN6O

665.2

SZ-L028017

Losartan N,O-Ditrityl Impurity

1796930-34-1

C60H51ClN6O

907.5

SZ-L028018

Losartan Trityl Methyl Ether Impurity

596-31-6

C20H18O

274.4

SZ-L028019

Losartan Acetyloxy Impurity

253678-97-6

C16H14N4O2

294.3

SZ-L028020

Losartan Aldehyde N2-Trityl Impurity

133910-00-6

C41H35ClN6O

663.2

SZ-L028021

Losartan Bromo N2-Trityl Impurity

133051-88-4

C33H25BrN4

557.5

SZ-L028022

Losartan Carboxylic Acid

124750-92-1

C22H21ClN6O2

436.9

SZ-L028023

4'-methyl-[1,1'-biphenyl]-2-carbonitrile

114772-53-1

C14H11N

193.3

SZ-L028024

2’-(2H-Tetrazol-5-yl)-[1,1’-biphenyl]-4-carboxaldehyde

151052-40-3

C14H10N4O

250.3

SZ-L028025

Losartan Related Compound A

124750-67-0

C22H20ClN3O

377.9

SZ-L028026

Losartan Related Compound B

114772-55-3

C22H22ClN3O

379.9

SZ-L028028

5-(4'-methylbiphenyl-2-yl)-1-trityl-1H-tetrazole

124750-53-4

C33H26N4

478.6

SynZeal Research offers all Losartan related impurities which certified COA with all characterization data like IR, Mass, HPLC purity,NMR & TGA report. We also provide CMR, DEPT and detailed structurecharacterization report as perrequirements. Losartan related products are being used by major pharmaceutical companies across the globe for their ANDA/DMF filing.

Losartan is an angiotensin-receptor blocker (ARB) that may be used alone or with other agents to treat hypertension. Losartan and its longer acting metabolite, E-3174, lower blood pressure by antagonizing the renin-angiotensin-aldosterone system (RAAS); they compete with angiotensin II for binding to the type-1 angiotensin II receptor (AT1) subtype and prevents the blood pressure increasing effects of angiotensin II. Unlike angiotensin-converting enzyme (ACE) inhibitors, ARBs do not have the adverse effect of dry cough. Losartan may be used to treat hypertension, isolated systolic hypertension, left ventricular hypertrophy and diabetic nephropathy. It may also be used as an alternative agent for the treatment of systolic dysfunction, myocardial infarction, coronary artery disease, and heart failure.