Jared Ray Mays, Ph.D.
CONTACT INFORMATION
Augustana University Tel: (605) 274-4815
Department of Chemistry Fax: (605) 274-4492
2001 S. Summit Avenue, FSC 325 Mobile: (210) 248-8462
Sioux Falls, SD 57197 Email: [email protected]
EDUCATION AND EMPLOYMENT
2015 – Current Augustana University (Augustana College, pre-2015) – Sioux Falls, SD
Associate Professor of Chemistry
2009 – 2015 Augustana College – Sioux Falls, SD
Assistant Professor of Chemistry
2007 – 2009 The University of Kansas – Lawrence, KS
Postdoctoral Research Associate, Medicinal Chemistry
2003 – 2007 The University of Wisconsin – Madison, WI
Ph.D., Pharmaceutical Sciences
1999 – 2003 Gustavus Adolphus College – St. Peter, MN
B.A., Chemistry, Biochemistry
TEACHING EXPERIENCE
2009 – Current Augustana University – Sioux Falls, SD
Assistant/Associate Professor of Chemistry
Courses Taught (Lecture and Laboratory)
– Chemistry 120: Introduction to Chemistry (2009-2012)
– Chemistry 120: Accelerated General Chemistry (2013-Current)
– Chemistry 145: Survey of Organic and Biochemistry
– Chemistry 201: Organic Chemistry I
– Chemistry 202: Organic Chemistry II
– Chemistry 305: Biochemistry
– Chemistry 330: Biochemistry & Medicinal Chemistry (2009-2016)
– Chemistry 330: Medicinal Chemistry (2017-Current)
– Chemistry 399: Independent Study
Courses Taught (Lecture)
– General Education 097: New Student Seminar
– Civitas 202: Pertinence
– General Education 492: Senior Capstone
– Civitas 395: Vocation Project
2001 – 2003 Gustavus Adolphus College – St. Peter, MN
Department Teaching Assistant (Eight Laboratory Sections)
– Biology 102: Organismal Biology
– Chemistry 141: Organic Chemistry I
– Chemistry 251: Organic Chemistry II
– Chemistry 255: Biochemistry I
– Chemistry 370: Quantitative Analysis
Laboratory Assistant
– Prepared unknown samples for use in Quantitative Analysis laboratory
Chemistry Department Tutor
– Tutored students in General, Organic, Inorganic, Analytical, Bio-, and Physical
Chemistries
– Co-head chemistry department tutor for 2002 – 2003 school year
RESEARCH EXPERIENCE
2009 – Current Augustana University – Sioux Falls, SD
Principle Investigator and Research Advisor
Research Assistants: Michael Amolins
Undergraduate Research Assistants: Kayla Vastenhout, Jordan Clark, Cody Lensing,
Ruthellen Tornberg, Joseph Keppen, Zachary Erickson, Amanda Johnson, Taylor
Yseth, Michaela Bunde, Ethan Pauley, Genevieve Tillotson, Sarah Fisher, Collin
Noldner, Justin Brown, John Klecker, Ellen Voigt, Chase Klingaman, Matt Wagner,
Carl Lang, Claire Fanta, Katie Tlusty, Marie Anderson, Eleanor Ronning, Alexa Snyder
Projects
– Preparation of non-natural isothiocyanate libraries and differential evaluation using
antiproliferation and ARE-induction assays
– Construction of non-natural glucosinolates
– Development of reverse-phase HPLC and UV-Vis methods to assess myrosinase-
dependent hydrolysis kinetics
– Exploration of methods to generate isothiocyanates from non-glucosinolates
– Preparation of intermediates in the phenolic glucosinolate biosynthetic pathway for
use in flux control studies
2007 – 2009 The University of Kansas – Lawrence, KS
Research Advisor: Brian S. J. Blagg, Ph.D.
Undergraduate Research Assistants: Stephanie Hill, Justin Moyers
Projects
– Preparation and evaluation of positional and directional isomers of the
amidocoumarin scaffold
– Syntheses and biological evaluation of chimeric flavone/isoflavone Hsp90 inhibitors
incorporating elements of novobiocin and derrubone
– Construction and biological assessment of quinoline- and naphthalene-derived
analogs of novobiocin to probe structure/activity relationships for C-terminal Hsp90
inhibition
Responsibilities
– Oversee training and mentoring for new postdoctoral associates and graduate students
– Maintain Blagg group chemical inventory and chemical/biological supply orders
2003 – 2007 The University of Wisconsin – Madison, WI
Research Advisor: Scott R. Rajski, Ph.D.
Undergraduate Research Assistants: Anni Zhao, James Avruch
Ph.D. Thesis: Synthetic and Biological Studies Directed at the Development of New
HDAC-Inhibiting Prodrugs
Projects
– Synthesis of non-natural glucosinolates and investigation of myrosinase-dependent
bioactivities
– Construction of analogs based on the bioactive metabolite of sulforaphane to study its
structure-activity relationships
– Synthesis of a structure-diversified isothiocyanate panel and assessment of compound
cytotoxicity relative to sulforaphane
– Synthesis of structurally-simplified cyclic disufides as bio-functional mimics of the
histone deacetylase inhibitor FK-228
– Semi-synthesis of S-adenosylhomocysteine and (S)-perillyl alcohol analogs
Responsibilities
– Instrument maintenance for Rajski group HPLC and lyophilizer
– Maintenance of School of Pharmacy anhydrous solvent-dispensing system, 400 MHz
Varian Gemini NMR Spectrometer, and 500 MHz Varian NMR Spectrometer
2001 – 2003 Gustavus Adolphus College – St. Peter, MN
Research Advisor: Gretchen E. Hofmeister, Ph.D.
Projects
– Syntheses and resolution of chiral bisphenol and trisphenol ligands for use in
enantioselective reactions with Ti(IV)
PUBLICATIONS AND PATENTS
**Undergraduate authors are designated in italics.
1. Anderson, R. H.; Lensing, C. J.; Forred, B. J.; Amolins, M. W.; Aegerter, C. L.; Vitiello, P. F.; Mays, J.
R. “Differentiating antiproliferative and chemopreventive modes of activity for electron-deficient aryl
isothiocyanates against human MCF-7 cells. ChemMedChem, 2018, 13, 1695–1710.
2. Klingaman, C. K.; Wagner, M. J.; Brown, J. R.; Klecker, J. B.; Pauley, E. H.; Noldner, C. J.; Mays, J.
R. “HPLC-based kinetics assay facilitates analysis of systems with multiple reaction products and
thermal enzyme denaturation. Anal. Biochem. 2017, 516, 37–47.
3. Klingaman, C. K.; Wagner, M. J.; Brown, J. R.; Klecker, J. B.; Pauley, E. H.; Noldner, C. J.; Mays, J.
R. “Synthesis and spectral characterization of 2,2-diphenylethyl glucosinolate and HPLC-based reaction
progress curve data for the enzymatic hydrolysis of glucosinolates by Sinapis alba myrosinase. Data in
Brief, 2016, 10, 151–181.
4. Vastenhout, K. J.; Tornberg, E. H.; Johnson, A. L.; Amolins, M. W.; Mays, J. R. High performance
liquid chromatography-based method to evaluate kinetics of glucosinolate hydrolysis by Sinapis alba
myrosinase. Anal. Biochem. 2014, 465, 105–113.
5. Earl, G. W.; Eichler, B. E.; Moore, B. E.; Weisshaar, D. E.; Duffy-Matzner, J. L.; Mays, J. R.; Dey, B.
K. Developing and sustaining a research program at a traditionally undergraduate liberal arts college:
Research, it’s our thing! Experiences in establishing a research culture at Augustana College, Sioux
Falls, SD. In Developing and Maintaining a Successful Undergraduate Research Program; ACS
Symposium Series 1156; American Chemical Society: Washington, DC, 2014; 61–80.
6. Mays, J. R.; Duffy-Matzner, J. L. Revamping a second semester organic chemistry course to meet the
new ACS biochemistry requirements. In Advances in Teaching Organic Chemistry; Duffy-Matzner, J.
L., Pacheco, K. A. O., Eds.; ACS Symposium Series 1108; American Chemical Society: Washington,
DC 2012; pp 177–183.
7. Mays, J. R.; Hill, S. A.; Moyers, J. T.; Blagg, B. S. J. The synthesis and evaluation of flavone and
isoflavone chimeras of novobiocin and derrubone. Bioorg. Med. Chem. 2010, 18, 249–266.
8. Mays, J. R.; Donnelly, A. C.; Burlison, J. A.; Nelson, J. T.; Vielhauer, G.; Holzbeierlein, J.; Blagg, B.
S. J. The design, synthesis and evaluation of coumarin ring derivatives of the novobiocin scaffold that
exhibit anti-proliferative activity. J. Org. Chem. 2009, 73, 8901–8920.
9. Mays, J. R.; Weller, R. L.; Sarfaraz, S.; Mukhtar, H.; Rajski, S. R. Identification, synthesis and
enzymology of nonnatural glucosinolate chemopreventive candidates. ChemBioChem. 2008, 9, 729–
747.
10. Mays, J. R.; Rajski, S.R. Preparation of isothiocyanates and glucosinolates as antitumor agents. 2008,
International Patent WO 2008008954.
11. Mays, J. R.; Restituyo, J. A.; Katzenberger, R.; Wassarman, D. A.; Rajski, S. R. Cyclic disulfides as
functional mimics of the histone deacetylase inhibitor FK-228. Tetrahedron Lett. 2007, 48, 4579–4583.
PRESENTATIONS
**Undergraduate authors are designated in italics, presenting author(s) for posters and seminars are underlined.
Augustana University – Sioux Falls, SD
1. Anderson, M. A.; Ronning, E. K.; Snyder, A. A.; Fisher, S. E.; Mays, J. R. “Synthesis of 4-
(Methylsulfinyl)benzyl and 3-Pyridylmethyl Glucosinolate via the Nitronate Pathway.” General
Organic Poster Session, 53rd American Chemical Society Midwest Regional Meeting, Ames, IA;
October 23, 2018.
2. Anderson, M. A.; Ronning, E. K.; Snyder, A. A.; Mays, J. R. “Evaluation of the Antiproliferation
Effects of Glucosinolates Against Humans MCF-7 Cells.” Undergraduate Poster Session, 53rd
American Chemical Society Midwest Regional Meeting, Ames, IA; October 22, 2018.
3. Anderson, M. A.; Ronning, E. K.; Snyder, A. A.; Mays, J. R. “Nitronate Syntheses of 4-
(Methylsulfinyl)benzyl and 3-Pyridylmethyl Glucosinolate and Evaluation of Antiproliferation
Effects of Glucosinolates on MCF-7 Cells.” Chemistry/Physics Seminar Series, Augustana University,
Sioux Falls, SD; October 19, 2018.
4. Anderson, M. A.; Ronning, E. K.; Snyder, A. A.; Fisher, S. E.; Mays, J. R. “Synthesis of 4-
(Methylsulfinyl)benzyl and 3-Pyridylmethyl Glucosinolate via the Nitronate Pathway.” 2018 Sioux
Valley ACS Undergraduate Research Symposium, Augustana University, Sioux Falls, SD; September
22, 2018. (Awarded 1st place in the judged poster competition).
5. Anderson, M. A.; Ronning, E. K.; Snyder, A. A.; Mays, J. R. “Evaluation of the Antiproliferation
Effects of Glucosinolates Against Humans MCF-7 Cells.” 2018 Sioux Valley ACS Undergraduate
Research Symposium, Augustana University, Sioux Falls, SD; September 22, 2018.
6. Anderson, M. A.; Ronning, E. K.; Snyder, A. A.; Fisher, S. E.; Mays, J. R. “Synthesis of 4-
(Methylsulfinyl)benzyl and 3-Pyridylmethyl Glucosinolate via the Nitronate Pathway.” Undergraduate
Summer Research Poster Session, Augustana University, Sioux Falls, SD; September 19, 2018.
7. Anderson, M. A.; Ronning, E. K.; Snyder, A. A.; Mays, J. R. “Evaluation of the Antiproliferation
Effects of Glucosinolates Against Humans MCF-7 Cells.” Undergraduate Summer Research Poster
Session, Augustana University, Sioux Falls, SD; September 19, 2018.
8. Anderson, M. A.; Ronning, E. K.; Snyder, A. A.; Fisher, S. E.; Mays, J. R. “Synthesis of 4-
(Methylsulfinyl)benzyl and 3-Pyridylmethyl Glucosinolate via the Nitronate Pathway.” Undergraduate
Research Symposium, Pierre, SD; July 25-26, 2018.
9. Anderson, M. A.; Ronning, E. K.; Snyder, A. A.; Mays, J. R. “Evaluation of the Antiproliferation
Effects of Glucosinolates Against Humans MCF-7 Cells.” Undergraduate Research Symposium,
Pierre, SD; July 25-26, 2018.
10. Fanta, C. C.; Tlusty, K. J.; Johnson, A. J.; Mays, J. R. “Synthesis and Evaluation of Substituted-Biaryl
Isothiocyanates.” Arthur Olsen Student Research Symposium 2018, Sioux Falls, SD; April 21, 2018.
11. Lang, C. W.; Voigt, E. M.; Pauley, E. H.; Mays, J. R. “Generation of Benzyl Isothiocyanate via
Photolysis of an ortho-Nitrobenzyl-Protected Analogue.” Arthur Olsen Student Research Symposium
2018, Sioux Falls, SD; April 21, 2018.
12. Lang, C. W.; Voigt, E. M.; Pauley, E. H.; Mays, J. R. “Generation of Benzyl Isothiocyanate via
Photolysis of an ortho-Nitrobenzyl-Protected Analogue.” Chemistry/Physics Seminar Series,
Augustana University, Sioux Falls, SD; March 2, 2018.
13. Fanta, C. C.; Tlusty, K. J.; Johnson, A. J.; Mays, J. R. “Synthesis and Evaluation of Substituted-Biaryl
Isothiocyanates.” Biochemistry Poster Session, 52nd American Chemical Society Midwest Regional
Meeting, Lawrence, KS; October 18-20, 2017.
14. Lang, C. W.; Voigt, E. M.; Pauley, E. H.; Mays, J. R. “Generation of Benzyl Isothiocyanate via
Photolysis of an ortho-Nitrobenzyl-Protected Analogue.” Biochemistry Poster Session, 52nd American
Chemical Society Midwest Regional Meeting, Lawrence, KS; October 18-20, 2017.
15. Fanta, C. C.; Tlusty, K. J.; Johnson, A. J.; Mays, J. R. “Synthesis and Evaluation of Substituted-Biaryl
Isothiocyanates.” Chemistry/Physics Seminar Series, Augustana University, Sioux Falls, SD; October
6, 2017.
16. Fanta, C. C.; Tlusty, K. J.; Johnson, A. J.; Mays, J. R. “Synthesis and Evaluation of Substituted-Biaryl
Isothiocyanates.” 2017 Sioux Valley ACS Undergraduate Research Symposium, Augustana
University, Sioux Falls, SD; September 29, 2017. (Awarded 3rd place in the judged poster
competition).
17. Lang, C. W.; Voigt, E. M.; Pauley, E. H.; Mays, J. R. “Generation of Benzyl Isothiocyanate via
Photolysis of an ortho-Nitrobenzyl-Protected Analogue.” 2017 Sioux Valley ACS Undergraduate
Research Symposium, Augustana University, Sioux Falls, SD; September 29, 2017. (Awarded 2nd
place in the judged poster competition).
18. Fanta, C. C.; Tlusty, K. J.; Johnson, A. J.; Mays, J. R. “Synthesis and Evaluation of Substituted-Biaryl
Isothiocyanates.” Undergraduate Summer Research Poster Session, Augustana University, Sioux Falls,
SD; September 13, 2017.
19. Lang, C. W.; Voigt, E. M.; Pauley, E. H.; Mays, J. R. “Generation of Benzyl Isothiocyanate via
Photolysis of an ortho-Nitrobenzyl-Protected Analogue.” Undergraduate Summer Research Poster
Session, Augustana University, Sioux Falls, SD; September 13, 2017.
20. Fanta, C. C.; Tlusty, K. J.; Johnson, A. J.; Mays, J. R. “Synthesis and Evaluation of Substituted-Biaryl
Isothiocyanates.” Undergraduate Research Symposium, Pierre, SD; August 2-3, 2017. (Awarded 2nd
place in the judged poster competition).
21. Lang, C. W.; Voigt, E. M.; Pauley, E. H.; Mays, J. R. “Generation of Benzyl Isothiocyanate via
Photolysis of an ortho-Nitrobenzyl-Protected Analogue.” Undergraduate Research Symposium, Pierre,
SD; August 2-3, 2017.
22. Mays, J. R. “Differentiating antiproliferative and chemopreventive modes of activity for electron-
deficient aryl isothiocyanates against human MCF-7 cells.” Eastern South Dakota Research
Symposium, Sanford Center, Sioux Falls, SD; May 31, 2017.
23. Klingaman, C. A.; Wagner, M. J.; Mays, J. R. “Enzymatic Hydrolysis of 2,2-Diphenylethyl
Glucosinolate.” Arthur Olsen Student Research Symposium 2017, Sioux Falls, SD; April 16, 2017.
24. Mays, J. R. “Differentiating antiproliferative and chemopreventive modes of activity for electron-
deficient aryl isothiocyanates against human MCF-7 cells.” General Poster Session, Division of
Medicinal Chemistry, 253rd ACS National Meeting, San Francisco, CA; April 2–6, 2017.
25. Mays, J. R. “Developing an interdisciplinary medicinal chemistry undergraduate research program at a
small, private, liberal arts university.” Advancing Undergraduate Research Symposium, Division of
Chemical Education, 253rd ACS National Meeting, San Francisco, CA; April 2–6, 2017.
26. Klingaman, C. A.; Wagner, M. J.; Mays, J. R. “Enzymatic Hydrolysis of 2,2-Diphenylethyl
Glucosinolate.” Undergraduate Research Poster Session, Division of Chemical Education, 253rd ACS
National Meeting, San Francisco, CA; April 2–6, 2017.
27. Klingaman, C. A.; Wagner, M. J.; Mays, J. R. “Enzymatic Hydrolysis of 2,2-Diphenylethyl
Glucosinolate.” Undergraduate Research Symposium, Augustana University, Sioux Falls, SD;
September 24, 2016.
28. Klingaman, C. A.; Wagner, M. J.; Mays, J. R. “Enzymatic Hydrolysis of 2,2-Diphenylethyl
Glucosinolate.” Undergraduate Summer Research Poster Session, Augustana University, Sioux Falls,
SD; September 21, 2016.
29. Klingaman, C. A.; Wagner, M. J.; Mays, J. R. “Glucotropaeolin and non-natural substrate 2,2-
diphenylethyl glucosinolate demonstrate consistent outcomes of hydrolysis by Sinapis alba
myrosinase.” Chemistry/Physics Department Seminar Series, Augustana University, Sioux Falls, SD;
September 16, 2016.
30. Klingaman, C. A.; Wagner, M. J.; Mays, J. R. “Enzymatic Hydrolysis of 2,2-Diphenylethyl
Glucosinolate.” Undergraduate Research Symposium, Pierre, SD; July 31-August 1, 2016.
31. Klingaman, C. A.; Wagner, M. J.; Mays, J. R. “Enzymatic Hydrolysis of 2,2-Diphenylethyl
Glucosinolate.” Arthur Olsen Student Research Symposium 2016, Sioux Falls, SD; April 16, 2016.
32. Klingaman, C. A.; Wagner, M. J.; Mays, J. R. “Enzymatic Hydrolysis of 2,2-Diphenylethyl
Glucosinolate.” Current Topics in Biochemistry Poster Session, 251st ACS National Meeting, San
Diego, CA; March 13–17, 2016.
33. Klingaman, C. A.; Wagner, M. J.; Mays, J. R. “Enzymatic Hydrolysis of 2,2-Diphenylethyl
Glucosinolate.” Biochemistry Poster Session, 50th American Chemical Society Midwest Regional
Meeting, St. Joseph, MO; October 21-23, 2015.
34. Klingaman, C. A.; Wagner, M. J.; Mays, J. R. “Enzymatic Hydrolysis of 2,2-Diphenylethyl
Glucosinolate.” Undergraduate Summer Research Poster Session, Augustana University, Sioux Falls,
SD; October 10, 2015.
35. Klingaman, C. A.; Wagner, M. J.; Mays, J. R. “Enzymatic Hydrolysis of 2,2-Diphenylethyl
Glucosinolate.” Chemistry Department Seminar Series, Augustana University, Sioux Falls, SD;
October 2, 2015.
36. Klingaman, C. A.; Wagner, M. J.; Mays, J. R. “Enzymatic Hydrolysis of 2,2-Diphenylethyl
Glucosinolate.” Undergraduate Chemistry Research Symposium, Graduate Education and Applied
Research Center, University of South Dakota, Sioux Falls, SD; September 26, 2015.
37. Klingaman, C. A.; Wagner, M. J.; Mays, J. R. “Enzymatic Hydrolysis of 2,2-Diphenylethyl
Glucosinolate.” Biomedical Research Infrastructure Network Convocation, The University of South
Dakota, Vermillion, SD; August 7, 2015.
38. Klingaman, C. A.; Wagner, M. J.; Mays, J. R. “Enzymatic Hydrolysis of 2,2-Diphenylethyl
Glucosinolate.” 2015 Sanford Summer Research Symposium, Sanford Research, Sioux Falls, SD;
August 6, 2015.
39. Klingaman, C. A.; Wagner, M. J.; Mays, J. R. “Enzymatic Hydrolysis of 2,2-Diphenylethyl
Glucosinolate.” 2015 South Dakota Undergraduate Research Symposium, Pierre, SD; July 30, 2015.
40. Brown, J. R.; Klecker, J. B.; Pauley, E. H.; Mays, J. R. “Preparation of 2,2-Diphenylethyl
Glucosinolate.” Chemistry and Physics Department Seminar Series, Augustana College, Sioux Falls,
SD; May 1, 2015.
41. Voigt, E. M.; Pauley, E. H.; Mays, J. R. “Preparation and Photolysis of Non-Glucosinolates.” Poster
Presentation, Arthur Olsen Student Research Symposium, Sioux Falls, SD; April 18, 2015.
42. Brown, J. R.; Klecker, J. B.; Pauley, E. H.; Mays, J. R. “Preparation of 2,2-Diphenylethyl
Glucosinolate.” Poster Presentation, Arthur Olsen Student Research Symposium, Sioux Falls, SD;
April 18, 2015.
43. Fisher, S. E.; Mays, J. R. “Fighting Cancer with Broccoli.” Arthur Olsen Student Research
Symposium, Sioux Falls, SD; April 18, 2015.
44. Mays, J. R. “Synthesis of Chemopreventive Glucosinolates: A Nitronate Approach” RSA Luncheon,
Augustana College, Sioux Falls, SD; April 8, 2015.
45. Voigt, E. M.; Pauley, E. H.; Mays, J. R. “Photolysis of Non-Glucosinolates to form ITCs.” Chemistry
and Physics Department Seminar Series, Augustana College, Sioux Falls, SD; March 27, 2015.
46. Voigt, E. M.; Pauley, E. H.; Mays, J. R. “Preparation and Photolysis of Non-Glucosinolates.”
Undergraduate Research in Medicinal Chemistry Poster Session, 249th ACS National Meeting,
Denver, CO; March 22–26, 2015.
47. Fisher, S. E.; Mays, J. R. “Fighting Cancer With Broccoli.” Chemistry and Physics Department
Seminar Series, Augustana College, Sioux Falls, SD; February 6, 2015.
48. Fisher, S. E.; Mays, J. R. “Exploration of the Nitronate Synthetic Pathway of Glucosinolates.” Poster
Session, 49th American Chemical Society Midwest Regional Meeting, Columbia, MO; November 12-
14, 2014.
49. Voigt, E. M.; Pauley, E. H.; Mays, J. R. “Preparation and Photolysis of Non-Glucosinolates.” Poster
Session, 49th American Chemical Society Midwest Regional Meeting, Columbia, MO; November 12-
14, 2014.
50. Brown, J. R.; Klecker, J. B.; Pauley, E. H.; Mays, J. R. “Preparation of 2,2-Diphenylethyl
Glucosinolate.” Poster Session, 49th American Chemical Society Midwest Regional Meeting,
Columbia, MO; November 12-14, 2014.
51. Fisher, S. E.; Mays, J. R. “Exploration of the Nitronate Synthetic Pathway of Glucosinolates.”
Undergraduate Chemistry Research Symposium, Graduate Education and Applied Research Center,
University of South Dakota, Sioux Falls, SD; September 20, 2014. (Awarded 2nd place in the judged
poster competition).
52. Voigt, E. M.; Pauley, E. H.; Mays, J. R. “Preparation and Photolysis of Non-Glucosinolates.”
Undergraduate Chemistry Research Symposium, Graduate Education and Applied Research Center,
University of South Dakota, Sioux Falls, SD; September 20, 2014.
53. Brown, J. R.; Klecker, J. B.; Pauley, E. H.; Mays, J. R. “Preparation of 2,2-Diphenylethyl
Glucosinolate.” Undergraduate Chemistry Research Symposium, Graduate Education and Applied
Research Center, University of South Dakota, Sioux Falls, SD; September 20, 2014.
54. Fisher, S. E.; Mays, J. R. “Exploration of the Nitronate Synthetic Pathway of Glucosinolates.”
Undergraduate Summer Research Poster Session, Augustana College, Sioux Falls, SD; September 17,
2014.
55. Voigt, E. M.; Pauley, E. H.; Mays, J. R. “Preparation and Photolysis of Non-Glucosinolates.”
Undergraduate Summer Research Poster Session, Augustana College, Sioux Falls, SD; September 17,
2014.
56. Brown, J. R.; Klecker, J. B.; Pauley, E. H.; Mays, J. R. “Preparation of 2,2-Diphenylethyl
Glucosinolate.” Undergraduate Summer Research Poster Session, Augustana College, Sioux Falls,
SD; September 17, 2014.
57. Voigt, E. M.; Pauley, E. H.; Mays, J. R. “Preparation and Photolysis of Non-Glucosinolates.” 2014
Sanford Summer Research Symposium, Sanford Research, Sioux Falls, SD; August 7, 2014.
58. Brown, J. R.; Klecker, J. B.; Pauley, E. H.; Mays, J. R. “Preparation of 2,2-Diphenylethyl
Glucosinolate.” 2014 Sanford Summer Research Symposium, Sanford Research, Sioux Falls, SD;
August 7, 2014.
59. Williams, T.; Seib, L.; Drake, R.; Mays, J. “My ZAB is dying! Exact mass determinations of ESI
invisible molecules on Qtofs with TAPCI, Toluene Atmospheric Pressure Chemical Ionization.” 62nd
ASMS Conference on Mass Spectrometry and Allied Topics, Baltimore, MD; June 15–19, 2014.
60. Tillotson, G. A.; Amolins, M. A.; Vitiello, P. F.; Mays, J. R. “Synthesis and Evaluation of Nitrile- and
Polyphenyl Isothiocyanates.” Chemistry and Physics Department Seminar Series, Augustana College,
Sioux Falls, SD; April 25, 2014.
61. Fisher, S. E.; Amolins, M. A.; Yseth, T. K.; Clark, J. J.; Vitiello, P. F.; Mays, J. R. “Synthesis and
Evaluation of Novel Non-Natural Isothiocyanates.” Poster Presentation, Augustana College
Symposium, Sioux Falls, SD; April 12, 2014.
62. Pauley, E. H.; Mays, J. R. “Preparation of a Photoactive Non-Glucosinolate Precursor to an
Isothiocyanate.” Poster Presentation, Augustana College Symposium, Sioux Falls, SD; April 12, 2014.
63. Noldner, C. J.; Pauley, E. H.; Mays, J. R. “Parallel Syntheses of Glucosinolates.” Poster Presentation,
Augustana College Symposium, Sioux Falls, SD; April 12, 2014.
64. Mays, J. R. “Glucosinolates: A Tale of Two Syntheses.” RSA Luncheon, Augustana College, Sioux
Falls, SD; March 26, 2014.
65. Fisher, S. E.; Amolins, M. A.; Yseth, T. K.; Clark, J. J.; Vitiello, P. F.; Mays, J. R. “Synthesis and
Evaluation of Novel Non-Natural Isothiocyanates.” Undergraduate Research in Medicinal Chemistry
Poster Session, 247th ACS National Meeting, Dallas, TX; March 16–20, 2014.
66. Pauley, E. H.; Mays, J. R. “Preparation of a Photoactive Non-Glucosinolate Precursor to an
Isothiocyanate.” Undergraduate Research in Medicinal Chemistry Poster Session, 247th ACS National
Meeting, Dallas, TX; March 16–20, 2014.
67. Mays, J. R.; Vastenhout, K. J.; Tornberg, R. H.; Johnson, A. J.; Amolins, M. W. Abstracts of Papers,
247th National Meeting of the American Chemical Society, Dallas, TX, March 16–20, 2014; American
Chemical Society: Washington, DC, 2014.
68. Noldner, C. J.; Pauley, E. H.; Mays, J. R. “Parallel Syntheses of Glucosinolates.” Chemistry and
Physics Department Seminar Series, Augustana College, Sioux Falls, SD; February 28, 2014.
69. Mays, J. R. “Chemistry and Life as a Chemist.” Boy Scout Chemistry Merit Badge Camp-In,
Washington Pavillion, Sioux Falls, SD; February 8, 2014.
70. Pauley, E. H.; Mays, J. R. “Preparation of a Photoactive Non-Glucosinolate Precursor to an
Isothiocyanate.” Chemistry and Physics Department Seminar Series, Augustana College, Sioux Falls,
SD; November 8, 2013.
71. Fisher, S. E.; Amolins, M. A.; Yseth, T. K.; Clark, J. J.; Vitiello, P. F.; Mays, J. R. “Synthesis and
Evaluation of Novel Non-Natural Isothiocyanates.” Poster Session, 48th American Chemical Society
Midwest Regional Meeting, Springfield, MO; October 26-19, 2013.
72. Noldner, C. J.; Pauley, E. H.; Mays, J. R. “Parallel Syntheses of Glucosinolates.” Poster Session, 48th
American Chemical Society Midwest Regional Meeting, Springfield, MO; October 26-19, 2013.
73. Pauley, E. H.; Mays, J. R. “Preparation of a Photoactive Non-Glucosinolate Precursor to an
Isothiocyanate.” Poster Session, 48th American Chemical Society Midwest Regional Meeting,
Springfield, MO; October 26-19, 2013.
74. Tillotson, G. A.; Amolins, M. A.; Vitiello, P. F.; Mays, J. R. “Synthesis and Evaluation of Nitrile- and
Polyphenyl Isothiocyanates.” Poster Session, 48th American Chemical Society Midwest Regional
Meeting, Springfield, MO; October 26-19, 2013.
75. Fisher, S. E.; Amolins, M. A.; Yseth, T. K.; Clark, J. J.; Vitiello, P. F.; Mays, J. R. “Synthesis and
Evaluation of Novel Non-Natural Isothiocyanates.” American Chemical Society Sioux Valley Section
Poster Competition, Graduate Education and Applied Research Center, Sioux Falls, SD; September
28, 2013. (Awarded 2nd place in the judged poster competition).
76. Noldner, C. J.; Pauley, E. H.; Mays, J. R. “Parallel Syntheses of Glucosinolates.” American Chemical
Society Sioux Valley Section Poster Competition, Graduate Education and Applied Research Center,
Sioux Falls, SD; September 28, 2013.
77. Pauley, E. H.; Mays, J. R. “Preparation of a Photoactive Non-Glucosinolate Precursor to an
Isothiocyanate.” American Chemical Society Sioux Valley Section Poster Competition, Graduate
Education and Applied Research Center, Sioux Falls, SD; September 28, 2013.
78. Fisher, S. E.; Amolins, M. A.; Yseth, T. K.; Clark, J. J.; Vitiello, P. F.; Mays, J. R. “Synthesis and
Evaluation of Novel Non-Natural Isothiocyanates.” Chemistry and Physics Department Seminar
Series, Augustana College, Sioux Falls, SD; September 20, 2013.
79. Fisher, S. E.; Amolins, M. A.; Yseth, T. K.; Clark, J. J.; Vitiello, P. F.; Mays, J. R. “Synthesis and
Evaluation of Novel Non-Natural Isothiocyanates.” Gilbert Science Center Fall Poster Presentation,
Augustana College, Sioux Falls, SD; September 18, 2013.
80. Noldner, C. J.; Pauley, E. H.; Mays, J. R. “Parallel Syntheses of Glucosinolates.” Gilbert Science
Center Fall Poster Presentation, Augustana College, Sioux Falls, SD; September 18, 2013.
81. Pauley, E. H.; Mays, J. R. “Preparation of a Photoactive Non-Glucosinolate Precursor to an
Isothiocyanate.” Gilbert Science Center Fall Poster Presentation, Augustana College, Sioux Falls, SD;
September 18, 2013.
82. Tillotson, G. A.; Amolins, M. A.; Vitiello, P. F.; Mays, J. R. “Synthesis and Evaluation of Nitrile- and
Polyphenyl Isothiocyanates.” Gilbert Science Center Fall Poster Presentation, Augustana College,
Sioux Falls, SD; September 18, 2013.
83. Fisher, S. E.; Amolins, M. A.; Yseth, T. K.; Clark, J. J.; Vitiello, P. F.; Mays, J. R. “Synthesis and
Evaluation of Novel Non-Natural Isothiocyanates.” Biomedical Research Infrastructure Network
Convocation, The University of South Dakota, Vermillion, SD; August 9, 2013.
84. Noldner, C. J.; Pauley, E. H.; Mays, J. R. “Parallel Syntheses of Glucosinolates.” Biomedical
Research Infrastructure Network Convocation, The University of South Dakota, Vermillion, SD;
August 9, 2013.
85. Pauley, E. H.; Mays, J. R. “Preparation of a Photoactive Non-Glucosinolate Precursor to an
Isothiocyanate.” Biomedical Research Infrastructure Network Convocation, The University of South
Dakota, Vermillion, SD; August 9, 2013.
86. Tillotson, G. A.; Amolins, M. A.; Vitiello, P. F.; Mays, J. R. “Synthesis and Evaluation of Nitrile- and
Polyphenyl Isothiocyanates.” Biomedical Research Infrastructure Network Convocation, The
University of South Dakota, Vermillion, SD; August 9, 2013.
87. Fisher, S. E.; Amolins, M. A.; Yseth, T. K.; Clark, J. J.; Vitiello, P. F.; Mays, J. R. “Synthesis and
Evaluation of Novel Non-Natural Isothiocyanates.” 2013 Summer Research Symposium, Sanford
Research, Sioux Falls, SD; August 8, 2013.
88. Noldner, C. J.; Pauley, E. H.; Mays, J. R. “Parallel Syntheses of Glucosinolates.” 2013 Summer
Research Symposium, Sanford Research, Sioux Falls, SD; August 8, 2013.
89. Pauley, E. H.; Mays, J. R. “Preparation of a Photoactive Non-Glucosinolate Precursor to an
Isothiocyanate.” 2013 Summer Research Symposium, Sanford Research, Sioux Falls, SD; August 8,
2013.
90. Tillotson, G. A.; Amolins, M. A.; Vitiello, P. F.; Mays, J. R. “Synthesis and Evaluation of Nitrile- and
Polyphenyl Isothiocyanates.” 2013 Summer Research Symposium, Sanford Research, Sioux Falls, SD;
August 8, 2013.
91. Amolins, M. W.; Forred, B. J.; Nagata, S.; Ise, T.; Tornberg, R. H.; Lensing, C. J.; Mays, J. R.;
Vitiello, P. F. “Isothiocyanate-Induced Antioxidant Response: Potential Mechanisms for
Chemoprevention.” 2013 Summer Research Symposium, Sanford Research, Sioux Falls, SD; August
8, 2013.
92. Tornberg, E. H.; Lensing, C. J.; Mays, J. R. “Synthesis and Evaluation of Novel Isothiocyanates.” Oral
Presentation, Augustana College Symposium, Sioux Falls, SD; April 20, 2013.
93. Johnson, A. L.; Mays, J. R. “Synthesis and Evaluation of Isothiocyanates (ITCs): Chemopreventive
and Chemotherapeutic Candidates.” Oral Presentation, Augustana College Symposium, Sioux Falls,
SD; April 20, 2013.
94. Yseth, T. K.; Amolins, M. W.; Clark, J. J.; Mays, J. R. Poster Presentation, Augustana College
Symposium, Sioux Falls, SD; April 20, 2013.
95. Johnson, A. L.; Mays, J. R. “Synthesis and Evaluation of Isothiocyanates (ITCs): Chemopreventive
and Chemotherapeutic Candidates.” Chemistry and Physics Department Seminar Series, Augustana
College, Sioux Falls, SD; April 19, 2013.
96. Tornberg, E. H.; Lensing, C. J.; Mays, J. R. “Synthesis and Evaluation of Novel Isothiocyanates.”
Poster Session, 98th Annual Meeting of the South Dakota Academy of Science , Sioux Falls, SD; April
13, 2013. Cancelled due to weather.
97. Johnson, A. L.; Mays, J. R. “Synthesis and Evaluation of Alkyl and Aryl Isothiocyanates as Anticancer
Agents.” Poster Session, 98th Annual Meeting of the South Dakota Academy of Science , Sioux Falls,
SD; April 13, 2013. Cancelled due to weather.
98. Tornberg, E. H.; Lensing, C. J.; Mays, J. R. “Synthesis and Evaluation of Novel Isothiocyanates.”
Undergraduate Poster Session, 245th ACS National Meeting, New Orleans, LA; April 7-11, 2013.
99. Johnson, A. L.; Mays, J. R. “Synthesis and Evaluation of Alkyl and Aryl Isothiocyanates as Anticancer
Agents.” Undergraduate Poster Session, 245th ACS National Meeting, New Orleans, LA; April 7-11,
2013.
100. Mays, J. R. “Glucosinolates, Isothiocyanates, and Cancer.” Advanced Chemistry Research Course,
Harrisburg, SD; December 12, 2012.
101. Yseth, T. K.; Amolins, M. W.; Clark, J. J.; Mays, J. R. “Synthesis and Evaluation of Methoxy
Isothiocyanates and Sulforaphane Homologs.” Chemistry and Physics Department Seminar Series,
Augustana College, Sioux Falls, SD; November 16, 2012.
102. Tornberg, E. H.; Lensing, C. J.; Mays, J. R. “Synthesis and Evaluation of Novel Isothiocyanates.”
Poster Session, 47th American Chemical Society Midwest Regional Meeting, Omaha, NE; October 24-
27, 2012.
103. Johnson, A. L.; Mays, J. R. “Synthesis and Evaluation of Alkyl and Aryl Isothiocyanates as Anticancer
Agents.” Poster Session, 47th American Chemical Society Midwest Regional Meeting, Omaha, NE;
October 24-27, 2012. (One of 9 outstanding posters from 94 entries)
104. Bunde, M. M.; Mays, J. R. “Synthesis and Evaluation of Phenoxy Isothiocyanates.” Poster Session,
47th American Chemical Society Midwest Regional Meeting, Omaha, NE; October 24-27, 2012.
105. Yseth, T. K.; Amolins, M. W.; Clark, J. J.; Mays, J. R. “Synthesis and Evaluation of Methoxy
Isothiocyanates and Sulforaphane Homologs.” Poster Session, 47th American Chemical Society
Midwest Regional Meeting, Omaha, NE; October 24-27, 2012.
106. Tornberg, E. H.; Lensing, C. J.; Mays, J. R. “Synthesis and Evaluation of Novel Isothiocyanates.”
American Chemical Society Sioux Valley Section Poster Competition, Graduate Education and
Applied Research Center, Sioux Falls, SD; September 29, 2012 (Awarded 2nd place in the judged
poster competition).
107. Johnson, A. L.; Mays, J. R. “Synthesis and Evaluation of Alkyl and Aryl Isothiocyanates as Anticancer
Agents.” American Chemical Society Sioux Valley Section Poster Competition, Graduate Education
and Applied Research Center, Sioux Falls, SD; September 29, 2012.
108. Tornberg, E. H.; Lensing, C. J.; Mays, J. R. “Synthesis and Evaluation of Novel Isothiocyanates.”
Chemistry and Physics Department Seminar Series, Augustana College, Sioux Falls, SD; September
14, 2012.
109. Tornberg, E. H.; Lensing, C. J.; Mays, J. R. “Synthesis and Evaluation of Novel Isothiocyanates.”
Gilbert Science Center Fall Poster Presentation, Augustana College, Sioux Falls, SD; September 12,
2012.
110. Johnson, A. L.; Mays, J. R. “Synthesis and Evaluation of Alkyl and Aryl Isothiocyanates as Anticancer
Agents.” Gilbert Science Center Fall Poster Presentation, Augustana College, Sioux Falls, SD;
September 12, 2012.
111. Yseth, T. K.; Amolins, M. W.; Clark, J. J.; Mays, J. R. “Synthesis and Evaluation of Methoxy
Isothiocyanates and Sulforaphane Homologs.” Gilbert Science Center Fall Poster Presentation,
Augustana College, Sioux Falls, SD; September 12, 2012.
112. Yseth, T. K.; Amolins, M. W.; Clark, J. J.; Mays, J. R. “Synthesis and Evaluation of Methoxy
Isothiocyanates and Sulforaphane Homologs.” Poster Session, Sanford Research/USD Cancer Biology
Symposium, Sanford Research, Sioux Falls, SD; August 30, 2012.
113. Bunde, M. M.; Mays, J. R. “Synthesis and Evaluation of Phenoxy Isothiocyanates.” South Dakota
Biomedical Research Infrastructure Network Convocation, The University of South Dakota,
Vermillion, SD; August 3, 2012.
114. Johnson, A. L.; Mays, J. R. “Synthesis and Evaluation of Alkyl and Aryl Isothiocyanates as Anticancer
Agents.” South Dakota Biomedical Research Infrastructure Network Convocation, The University of
South Dakota, Vermillion, SD; August 3, 2012.
115. Tornberg, E. H.; Lensing, C. J.; Mays, J. R. “Synthesis and Evaluation of Novel Isothiocyanates.”
South Dakota Biomedical Research Infrastructure Network Convocation, The University of South
Dakota, Vermillion, SD; August 3, 2012.
116. Bunde, M. M.; Mays, J. R. “Synthesis and Evaluation of Phenoxy Isothiocyanates.” Poster Session,
2012 Sanford Summer Research Symposium, Sanford Research, Sioux Falls, SD; August 2, 2012.
117. Johnson, A. L.; Mays, J. R. “Synthesis and Evaluation of Alkyl and Aryl Isothiocyanates as Anticancer
Agents.” Poster Session, 2012 Sanford Summer Research Symposium, Sanford Research, Sioux Falls,
SD; August 2, 2012.
118. Tornberg, E. H.; Lensing, C. J.; Mays, J. R. “Synthesis and Evaluation of Novel Isothiocyanates.”
Poster Session, 2012 Sanford Summer Research Symposium, Sanford Research, Sioux Falls, SD;
August 2, 2012.
119. Yseth, T. K.; Amolins, M. W.; Clark, J. J.; Mays, J. R. “Synthesis and Evaluation of Methoxy
Isothiocyanates and Sulforaphane Homologs.” Poster Session, 2012 Sanford Summer Research
Symposium, Sanford Research, Sioux Falls, SD; August 2, 2012.
120. Tornberg, E. H.; Lensing, C. J.; Mays, J. R. “Synthesis and Evaluation of Novel Isothiocyanates.”
Poster Session, 1st Annual It’s All About Science Festival, Sanford Research, Sioux Falls, SD; July 28,
2012.
121. Vastenhout, K.; Mays, J. R. “Synthesis and RP-HPLC Monitored Hydrolysis of Non-Natural
Glucosinolates.” Chemistry and Physics Department Seminar Series, Augustana College, Sioux Falls,
SD; May 11, 2012.
122. Vastenhout, K.; Mays, J. R. “Synthesis and RP-HPLC Monitored Hydrolysis of Non-Natural
Glucosinolates.” Oral Presentation, Augustana College Symposium, Sioux Falls, SD; April 20-21,
2012.
123. Keppen, J. W.; Clark, J. J.; Mays, J. R. “Synthesis of 3-Pyridylmethyl Glucosinolate from 3-
Pyridylacetonitrile.” Poster Presentation, Augustana College Symposium, Sioux Falls, SD; April 20-
21, 2012.
124. Tornberg, E. H.; Lensing, C. J.; Mays, J. R. “Synthesis and Evaluation of Novel Isothiocyanates.”
Poster Presentation, Augustana College Symposium, Sioux Falls, SD; April 20-21, 2012.
125. Keppen, J. W.; Clark, J. J.; Mays, J. R. “Synthesis of 3-Pyridylmethyl Glucosinolate from 3-
Pyridylacetonitrile.” Chemistry and Physics Department Seminar Series, Augustana College, Sioux
Falls, SD; April 20, 2012.
126. Vastenhout, K.; Mays, J. R. “Synthesis and RP-HPLC Monitored Hydrolysis of Non-Natural
Glucosinolates.” Poster Presentation, 97th South Dakota Academy of Science Annual Meeting,
Vermillion, SD; April 14, 2012.
127. Keppen, J. W.; Clark, J. J.; Mays, J. R. “Synthesis of 3-Pyridylmethyl Glucosinolate from 3-
Pyridylacetonitrile.” Poster Presentation, 97th South Dakota Academy of Science Annual Meeting,
Vermillion, SD; April 14, 2012.
128. Tornberg, E. H.; Lensing, C. J.; Mays, J. R. “Synthesis and Evaluation of Novel Isothiocyanates.”
Poster Presentation, 97th South Dakota Academy of Science Annual Meeting, Vermillion, SD; April
14, 2012.
129. Vastenhout, K.; Mays, J. R. “Synthesis and RP-HPLC Monitored Hydrolysis of Non-Natural
Glucosinolates.” Undergraduate Poster Session, 243rd ACS National Meeting, San Diego, CA; March
25-29, 2012.
130. Tornberg, E. H.; Lensing, C. J.; Mays, J. R. “Synthesis and Evaluation of Novel Isothiocyanates.”
Undergraduate Poster Session, 243rd ACS National Meeting, San Diego, CA; March 25-29, 2012.
131. Tornberg, E. H.; Lensing, C. J.; Mays, J. R. “Synthesis and Evaluation of Novel Isothiocyanates.”
Chemistry and Physics Department Seminar Series, Augustana College, Sioux Falls, SD; February 17,
2012.
132. Keppen, J. W.; Clark, J. J.; Mays, J. R. “Synthesis of 3-Pyridylmethyl Glucosinolate from 3-
Pyridylacetonitrile.” American Chemical Society Midwest/Great Lakes Joint Regional Meeting,
Organic Chemistry Poster Session, St. Louis, MO; October 26-28, 2011.
133. Vastenhout, K.; Mays, J. R. “Synthesis and RP-HPLC Monitored Hydrolysis of Non-Natural
Glucosinolates.” American Chemical Society Midwest/Great Lakes Joint Regional Meeting,
Biochemistry Poster Session, St. Louis, MO; October 26-28, 2011. (Awarded best poster in the
biochemistry subcategory)
134. Erickson, Z.; Mays, J. R. “Synthesis of Isothiocyanates with Electron-Deficient Aromatic Rings.”
American Chemical Society Midwest/Great Lakes Joint Regional Meeting, Organic Chemistry Poster
Session, St. Louis, MO; October 26-28, 2011.
135. Mays, J. R. “Glucosinolates, isothiocyanates, and cancer: The story of what we can learn from
broccoli.” RSA Luncheon, Augustana College, Sioux Falls, SD; September 29, 2011.
136. Keppen, J. W.; Clark, J. J.; Mays, J. R. “Synthesis of 3-Pyridylmethyl Glucosinolate from 3-
Pyridylacetonitrile.” American Chemical Society Sioux Valley Section Poster Competition, The
University of South Dakota, Vermillion, SD; September 24, 2011.
137. Vastenhout, K.; Mays, J. R. “Synthesis and RP-HPLC Monitored Hydrolysis of Non-Natural
Glucosinolates.” American Chemical Society Sioux Valley Section Poster Competition, The
University of South Dakota, Vermillion, SD; September 24, 2011.
138. Tornberg, E. H.; Lensing, C. J.; Mays, J. R. “Synthesis and Evaluation of Novel Isothiocyanates.”
American Chemical Society Sioux Valley Section Poster Competition, The University of South
Dakota, Vermillion, SD; September 24, 2011.
139. Keppen, J. W.; Clark, J. J.; Mays, J. R. “Synthesis of 3-Pyridylmethyl Glucosinolate from 3-
Pyridylacetonitrile.” Gilbert Science Center Fall Poster Presentation, Augustana College, Sioux Falls,
SD; September 14, 2011.
140. Vastenhout, K.; Mays, J. R. “Synthesis and RP-HPLC Monitored Hydrolysis of Non-Natural
Glucosinolates.” Gilbert Science Center Fall Poster Presentation, Augustana College, Sioux Falls, SD;
September 14, 2011.
141. Tornberg, E. H.; Lensing, C. J.; Mays, J. R. “Synthesis and Evaluation of Novel Isothiocyanates.”
Gilbert Science Center Fall Poster Presentation, Augustana College, Sioux Falls, SD; September 14,
2011.
142. Keppen, J. W.; Clark, J. J.; Mays, J. R. “Synthesis of 3-Pyridylmethyl Glucosinolate from 3-
Pyridylacetonitrile.” Poster Session, 2nd Annual Student Research Symposium at Sanford
Research/USD, Sioux Falls, SD; August 4, 2011.
143. Vastenhout, K.; Mays, J. R. “Synthesis and RP-HPLC Monitored Hydrolysis of Non-Natural
Glucosinolates.” Poster Session, 2nd Annual Student Research Symposium at Sanford Research/USD,
Sioux Falls, SD; August 4, 2011.
144. Erickson, Z.; Mays, J. R. “Synthesis of Isothiocyanates with Electron-Deficient Aromatic Rings.”
Poster Session, 2nd Annual Student Research Symposium at Sanford Research/USD, Sioux Falls, SD;
August 4, 2011.
145. Tornberg, E. H.; Lensing, C. J.; Mays, J. R. “Synthesis and Evaluation of Novel Isothiocyanates.”
Poster Session, 2nd Annual Student Research Symposium at Sanford Research/USD, Sioux Falls, SD;
August 4, 2011.
146. Keppen, J. W.; Clark, J. J.; Mays, J. R. “Synthesis of 3-Pyridylmethyl Glucosinolate from 3-
Pyridylacetonitrile.” South Dakota Biomedical Research Infrastructure Network Convocation, The
University of South Dakota, Vermillion, SD; July 29, 2011.
147. Vastenhout, K.; Mays, J. R. “Synthesis and RP-HPLC Monitored Hydrolysis of Non-Natural
Glucosinolates.” South Dakota Biomedical Research Infrastructure Network Convocation, The
University of South Dakota, Vermillion, SD; July 29, 2011.
148. Erickson, Z.; Mays, J. R. “Synthesis of Isothiocyanates with Electron-Deficient Aromatic Rings.”
Poster Session, Northern Plains Undergraduate Research Conference Symposium, Ponca State Park,
Ponca, NE; July 29, 2011.
149. Tornberg, E. H.; Lensing, C. J.; Mays, J. R. “Synthesis and Evaluation of Novel Isothiocyanates.”
Poster Session, Northern Plains Undergraduate Research Conference Symposium, Ponca State Park,
Ponca, NE; July 29, 2011.
150. Vastenhout, K.; Mays, J. R. “Synthesis and RP-HPLC Monitored Hydrolysis of Non-Natural
Glucosinolates.” Poster Session, 96th Annual Meeting of the South Dakota Academy of Science,
Oacoma, SD; April 9, 2011.
151. Clark, J. J.; Mays, J. R. “Synthesis of Heterocyclic Glucosinolates and Sulforaphane.” Poster Session,
96th Annual Meeting of the South Dakota Academy of Science, Oacoma, SD; April 9, 2011.
152. Lensing, C. J.; Mays, J. R. “Synthesis and Evaluation of Novel Isothiocyanates.” Augustana College
Symposium, Sioux Falls, SD; April 9, 2011.
153. Vastenhout, K.; Mays, J. R. “Synthesis and RP-HPLC Monitored Hydrolysis of Non-Natural
Glucosinolates.” Undergraduate Poster Session, 241st ACS National Meeting, Anaheim, CA; March
27-31, 2011.
154. Lensing, C. J.; Mays, J. R. “Synthesis and Evaluation of Novel Isothiocyanates.” Undergraduate
Poster Session, 241st ACS National Meeting, Anaheim, CA; March 27-31, 2011.
155. Vastenhout, K.; Mays, J. R. “Synthesis and RP-HPLC Monitored Hydrolysis of Non-Natural
Glucosinolates.” Chemistry and Physics Departmental Seminar Series, Augustana College, Sioux
Falls, SD; December 14, 2010.
156. Lensing, C. J.; Mays, J. R. “Synthesis and Evaluation of Novel Isothiocyanates.” Chemistry and
Physics Departmental Seminar Series, Augustana College, Sioux Falls, SD; November 19, 2010.
157. Clark, J. J.; Mays, J. R. “Synthesis of Heterocyclic Glucosinolates and Sulforaphane.” American
Chemical Society Midwest Regional Meeting, Undergraduate Research Poster Session, Wichita, KS;
October 27, 2010.
158. Vastenhout, K.; Mays, J. R. “Synthesis and RP-HPLC Monitored Hydrolysis of Non-Natural
Glucosinolates.” American Chemical Society Midwest Regional Meeting, Undergraduate Research
Poster Session, Wichita, KS; October 27, 2010.
159. Lensing, C. J.; Mays, J. R. “Synthesis and Evaluation of Novel Isothiocyanates.” American Chemical
Society Midwest Regional Meeting, Undergraduate Research Poster Session, Wichita, KS; October
27, 2010.
160. Mays, J. R. “Synthetic Organic Isothiocyanates: Novel Chemoprotective Agents?” BCAAP Seminar,
South Dakota State University, Brookings, SD; October 20, 2010.
161. Clark, J. J.; Mays, J. R. “Synthesis of Heterocyclic Glucosinolates and Sulforaphane.” American
Chemical Society Sioux Valley Section Poster Competition, The University of South Dakota,
Vermillion, SD; October 16, 2010.
162. Vastenhout, K.; Mays, J. R. “Synthesis and RP-HPLC Monitored Hydrolysis of Non-Natural
Glucosinolates.” American Chemical Society Sioux Valley Section Poster Competition, The
University of South Dakota, Vermillion, SD; October 16, 2010.
163. Lensing, C. J.; Mays, J. R. “Synthesis and Evaluation of Novel Isothiocyanates.” American Chemical
Society Sioux Valley Section Poster Competition, The University of South Dakota, Vermillion, SD;
October 16, 2010.
164. Clark, J. J.; Mays, J. R. “Synthesis of Heterocyclic Glucosinolates and Sulforaphane.” Chemistry and
Physics Departmental Seminar Series, Augustana College, Sioux Falls, SD; October 1, 2010.
165. Clark, J. J.; Mays, J. R. “Synthesis of Heterocyclic Glucosinolates and Sulforaphane.” Gilbert
Science Center Fall Poster Presentation, Augustana College, Sioux Falls, SD; September 22, 2010.
166. Vastenhout, K.; Mays, J. R. “Synthesis and RP-HPLC Monitored Hydrolysis of Non-Natural
Glucosinolates.” Gilbert Science Center Fall Poster Presentation, Augustana College, Sioux Falls, SD;
September 22, 2010.
167. Lensing, C. J.; Mays, J. R. “Synthesis and Evaluation of Novel Isothiocyanates.” Gilbert Science
Center Fall Poster Presentation, Augustana College, Sioux Falls, SD; September 22, 2010.
168. Lensing, C. J.; Mays, J. R. “Synthesis and Evaluation of Novel Isothiocyanates.” Sanford Program for
Undergraduate Research Poster Symposium, Sanford Research, Sioux Falls, SD; August 4, 2010.
169. Vastenhout, K.; Mays, J. R. “Synthesis and RP-HPLC Monitored Hydrolysis of Non-Natural
Glucosinolates.” South Dakota Biomedical Research Infrastructure Network Convocation, The
University of South Dakota, Vermillion, SD; July 26, 2010.
170. Clark, J. J.; Mays, J. R. “Synthesis of Heterocyclic Glucosinolates and Sulforaphane.” South Dakota
Biomedical Research Infrastructure Network Convocation, The University of South Dakota,
Vermillion, SD; July 26, 2010.
171. Mays, J. R. “Chemical biology approaches to expand the utility of organic isothiocyanates as cancer
chemoprotective agents.” Chemistry and Physics Departmental Seminar Series, Augustana College,
Sioux Falls, SD; October 2, 2009.
172. Mays, J. R. “Chemical biology approaches to expand the utility of organic isothiocyanates as cancer
chemoprotective agents.” Cancer Biology Research Center, Sanford School of Medicine, Sioux Falls,
SD; August 17, 2009.
The University of Kansas – Lawrence, KS
173. Mays, J. R.; Hill, S. A.; Moyers, J. T.; Blagg, B. S. J. “Synthesis and evaluation of flavones and
isoflavone chimeras of novobiocin and derrubone.” National Institutes of Health Poster Session, The
University of Kansas, Lawrence, KS; October 24, 2008.
The University of Wisconsin – Madison, WI
174. Mays, J. R.; Weller, R.L.; Sarfaraz, S.; Muhktar, H.; Rajski, S.R. “Development of new myrosinase-
dependent histone deacetylase inhibitors as chemoprotectants.” 2005 Midwest Enzyme Chemistry
Conference, Chicago, IL; October 2005.
Gustavus Adolphus College – St. Peter, MN
175. Mays, J. R.; Hofmeister, G.E. “Synthesis and resolution of chiral trisphenols: An approach in
stereochemical control in Lewis-acid catalyzed reactions.” 225th American Chemical Society National
Meeting, New Orleans, LA; March 2003.
GRANT ACTIVITY
1. “Non-Natural Isothiocyanates as Anticancer Agents.” South Dakota BRIN Faculty Fellowship Program,
Role: Principle Investigator, June 1, 2015, Requested $99,994. Fully funded.
2. Participation in “South Dakota Biomedical Research Infrastructure Network (BRIN).” National
Institutes of Health Sponsored IDeA Award, Role: Research Mentor, 2015, Requested $14,400,000.
Fully funded (P20, GM103443), ~$15,000 in support allocated to J. R. Mays per year of participation.
Intended participation through summer 2020.
3. Participation in “South Dakota Experimental Program to Stimulate Competitive Research (SD
EPSCoR).” National Science Foundation RII Track 1 Award (IIA-1355423) and the state of South
Dakota, Role: Research Mentor, 2014, Requested $20,000,000. Fully funded. ~$10,000 in support
allocated to J. R. Mays per year of participation.
4. “Preparation of lead chemopreventive isothiocyanates and glucosinolates.” Augustana Research/Artist
Fund, Role: Principle Investigator, February 2014, Requested $6,580. Fully funded.
5. “Molecular Modeling and Simulation Using SYBYL-X at Augustana College.” 2014 Pittsburgh
Conference Memorial National College Grants Program, Role: Principle Investigator, September 2013,
Requested $10,000. Not funded.
6. “Synthesis and Kinetic Evaluation of Non-Natural Glucosinolates.” Augustana Research/Artist Fund,
Role: Principle Investigator, February 2013, Requested $7,000. Fully funded.
7. “Non-natural Isothiocyanates and their Evaluation against Human Breast Cancers.” National Institutes
of Health Academic Research Enhancement Award, Role: Principle Investigator, October 2012,
Requested $368,683. Not funded (impact score = 56).
8. “REU Site in Cellular and Molecular Biology at Sanford Research and Augustana College.” NSF REU
1262744, National Science Foundation, Role: Senior Personnel (Research Mentor), September 2012,
Requested $350,491. Fully funded.
9. “Preparation and Multifaceted Evaluation of Novel Non-Natural Isothiocyanates as Anticancer Agents.”
Sanford Research Cancer COBRE Pilot Grant (8P20GM103548), Role: Principle Investigator,
Requested $10,104, June 2012. Fully funded.
10. “Synthesis and Kinetic Evaluation of Non-Natural Glucosinolates: Understanding the Structural Basis
for Myrosinase-Catalyzed Generation of Isothiocyanates.” Research Corporation for Science
Advancement Single Investigator Cottrell College Science Award, Role: Principle Investigator,
Requested $45,000, November 2011. Not funded.
11. “Thioredoxin-1 Regulation of Isothiocyanate Chemoprotection.” PhRMA Foundation, Role:
Collaborator, September 2011. Not funded.
12. “Non-Natural Isothiocyanates and Novel Mechanisms of Isothiocyanate Generation: Studies Toward the
Development of Improved Anticarcinogenic Agents.” National Institutes of Health Academic Research
Enhancement Award, Role: Principle Investigator, September 2009, Requested $311,280. Not funded.
13. Participation in “South Dakota Biomedical Research Infrastructure Network (BRIN).” National
Institutes of Health Sponsored IDeA Award, Role: Research Mentor, 2008, Requested $16,600,000.
Fully funded (2 P20, RR016479), $90,000 in startup funds allocated to J. R. Mays for 2009 – 2011,
~$18,000 per year in salary, student stipends, and materials. Began participation in summer 2010.
Intended participation through summer 2013.
14. “Redesigning DNA Gyrase Inhibitor Cyclothialidine to be a Selective Inhibitor of Hsp90.” National
Institutes of Health Ruth L. Kirchstein National Research Service Award Individual Fellowship, Role:
Principle Investigator, December 2007, Requested $100,000. Not funded.
15. “Redesigning DNA Gyrase Inhibitor Cyclothialidine to be a Selective Inhibitor of Hsp90.”Department
of Defense Congressionally Directed Medical Research Programs Prostate Cancer Research Program,
Prostate Cancer Training Award, Role: Principle Investigator, June 2008, Requested $114,998. Not
funded.
16. “Redesigning DNA Gyrase Inhibitor Cyclothialidine to be a Selective Inhibitor of Hsp90.” American
Cancer Society Postdoctoral Fellowship, Role: Principle Investigator, October 2007, Requested
$138,000. Not funded.
17. Participation in “The Development and Evaluation of Purine and Coumarin Based Hsp90 Inhibitors.”
National Institutes of Health and the National Cancer Institute, Role: Postdoctoral Associate, 2005,
Requested $1,829,000. Fully funded (2 U01 CA120458), $45,000 per year for salary and benefits from
2007 – 2009.
18. “New Tools for Histone Deacetylase Inhibition.” National Science Foundation Graduate Research
Fellowship Program, Role: Principle Investigator, November 2004, Requested $40,500. Not funded.
19. “Development of New GI-Specific Histone Deacetyase Inhibitors as Chemoprotectants.” National
Institutes of Health, Role: Graduate Student, November 2004, Requested $100,000. Fully funded (R03
CA117519).
20. “Chemistry Biology Interface Training Grant.” National Institutes of Health and the National Institute of
General Medical Sciences, Role: Trainee, 1993, Requested $4,594,000. Fully funded (5 T32
GM008505-18), ~$30,000 per year allocated to J. R. Mays for salary and benefits from 2004 – 2007.
QUALIFICATION SUMMARY
Knowledge of the properties of organic and biochemical materials
Knowledge of the air- and water-sensitive synthetic theory and methodology used to prepare organic and
biochemical compounds
Knowledge of the techniques used to purify organic and biochemical compounds, including:
chromatography (flash [SiO2], MPLC, HPLC), electrophoresis, and crystallization
Comprehensive understanding of the instrumentation and experiments used to characterize organic and
biochemical compounds, including: NMR, FT-IR, MS, HRMS, and UV-Vis
Areas of teaching competence include general, organic, biochemistry, medicinal, and some analytical
chemistry
TECHNIQUES AND INSTRUMENTATION
Instrumental Methods NMR (1H, 13C, 19F, kinetic NMR, dynamic NMR), IR, MS, GCMS, UV/Vis,
HPLC, Molecular Modeling (Chimera, SYBYL-X)
Separation & Purification PTLC, column chromatography (SiO2), recrystallization, gel electrophoresis
(SDS-PAGE)
Organic Chemistry multi-step chemical synthesis, anhydrous synthetic methodology (vacuum
manifold, glove box), natural product semi-synthesis, construction of
chemical libraries
Molecular Biology protein isolation, western blot analysis, cell culture, antiproliferation assays
(manual, high-throughput)
Software Microsoft Office (Excel, Word, PowerPoint), Cambridgesoft ChemDraw,
Adobe Photoshop, Adobe Illustrator, Adobe Dreamweaver, Thompson
EndNote, Xlfit, SigmaPlot, GraphPad Prism, PC, Linux, Windows (Windows
95 – Windows 7)
RESEARCH INTERESTS
Chemical syntheses of bioactive organic compounds
Synthesis and application of prodrug mechanisms for drug delivery
Development of small molecules with anticancer activity (both chemotherapeutic and chemopreventive)
Analysis of Michaelis–Menten enzyme kinetic processes
Target-oriented construction of chemical libraries
Combinatorial chemistry and convergent syntheses
Identification of 2D- and 3D-quantitative structure–activity relationships (QSAR)
Computational modeling for drug/receptor complexes
Development of in vitro biochemical assays to screen chemical libraries
ACADEMIC SERVICE
Augustana University – Sioux Falls, SD
2018 – Current Peer Reviewer, Bioorganic Chemistry
2017 – Current Curriculum Council
2016 – Current Peer Reviewer, Journal of Food Science and Technology
2015 – 2016 Mentor, New Faculty Mentoring Program
2015 – Current Peer Reviewer, Computational Biology and Chemistry
2015 – Current Peer Reviewer, The Journal of Natural Products
2015 Chair, Chemistry Laboratory Instructor Search Committee
2014 – 2016 Teacher Education Committee
2014 – Current Peer Reviewer, SciTechnol: Applied Bioinformatics & Computational Biology
2013 Food, Faculty, and Film, “Monty Python and the Holy Grail”; November 5, 2013
2013 – 2016 Coordinator, Chemistry/Physics Department Seminar Series
2013 Examiner, Graduate Thesis for Van Quan Vo, La Trobe University, Victoria, Australia
2013 – Current Textbook Reviewer, John Wiley & Sons
2013 Barry M. Goldwater Foundation Subcommittee: All-Goldwater Scholar Event
2013 – Current Textbook Reviewer, Cengage Learning TextReviews
2013 – 2014 Program Steering Committee for the Froiland/Gilbert Science Center Project
2013 General Education Proposal Subcommittee: The Natural Sciences
2013 Fast Five Presentation, “Musings on the Liberal Arts by a Medicinal Chemist”; March
20, 2013
2012 – 2016 Civitas Committee
2012 – Current Biochemistry Major Steering Committee
2012 – 2016 Faculty Advisor to the Augustana University Chapter of the Student Affiliates of the
American Chemical Society
2012 – Current Peer Reviewer, Mini Reviews in Medicinal Chemistry
2012 – Current Barry M. Goldwater Scholarship National Selection Committee
2012 – Current Peer Reviewer, The Journal of Medicinal Chemistry
2012 Chair of Moral Values Activity, “Life and Death”; March 29, 2012
2012 Chapel Sermon, “Shades of Grey?”; January 11, 2012
2011 – Current Distinguished Scholars Competition Interview Team
2011 Approval of W-Component for Chemistry 330: Biochemistry and Medicinal Chemistry
2010 – 2011 Faculty Advisor to the Augustana College Chapter of the Student Affiliates of the
American Chemical Society
2010 – 2012 Mikkelsen Library Committee (Chair, 2011 – 2012)
2010 Faculty Enlightenment, Augustana Faculty Meeting ; October 6, 2010
2009 – Current Y.T. Johnson Science Day Committee
2009 – Current Y. T. Johnson Science Day, Break-Out Session Leader
2009 – Current Biochemistry Major Co-Coordinator
2009 Biochemistry Major Task Force
The University of Wisconsin – Madison, WI
2004 – 2006 Pharmaceutical Sciences Graduate Liaison Committee
PROFESSIONAL AFFILLIATIONS
Augustana University – Sioux Falls, SD
2010 – Current The American Chemical Society, Division of Medicinal Chemistry
The University of Wisconsin – Madison, WI
2004 – 2006 The American Chemical Society
HONORS AND AWARDS
Augustana University – Sioux Falls, SD
2018 1st Place, American Chemical Society Sioux Valley Section 2018 Poster Competition,
POET Research, Sioux Falls, SD
2017 2nd Place, American Chemical Society Sioux Valley Section 2017 Poster Competition,
Augustana University, Sioux Falls, SD
2017 3rd Place, American Chemical Society Sioux Valley Section 2017 Poster Competition,
Augustana University, Sioux Falls, SD
2017 2nd Place, Undergraduate Research Symposium Poster Competition, Pierre, SD
2016 Honorable Mention Student Chapter Awarded to the Augustana College Student
Affiliates of the American Chemical Society
2015 Commendable Student Chapter Awarded to the Augustana College Student Affiliates of
the American Chemical Society
2014 Green Chemistry Award for the Augustana College Chapter for the Student Affiliates of
the American Chemical Society
2014 Commendable Student Chapter Awarded to the Augustana College Student Affiliates of
the American Chemical Society
2014 2nd Place, American Chemical Society Sioux Valley Section 2014 Poster Competition,
Graduate Education and Applied Research Center, Sioux Falls, SD
2013 2nd Place, American Chemical Society Sioux Valley Section 2013 Poster Competition,
Graduate Education and Applied Research Center, Sioux Falls, SD
2013 Green Chemistry Award for the Augustana College Chapter for the Student Affiliates of
the American Chemical Society
2013 Commendable Student Chapter Awarded to the Augustana College Student Affiliates of
the American Chemical Society
2012 Outstanding Poster, Midwest Regional Meeting of the American Chemical Society,
Omaha, NE
2012 2nd Place, American Chemical Society Sioux Valley Section 2012 Poster Competition,
Graduate Education and Applied Research Center, Sioux Falls, SD
2011 Green Chemistry Award for the Augustana College Chapter for the Student Affiliates of
the American Chemical Society
2011 Outstanding Student Chapter Awarded to the Augustana College Student Affiliates of the
American Chemical Society
2011 Best Poster (Biochemistry subcategory), Midwest/Great Lakes Joint Meeting of the
American Chemical Society, St. Louis, MO
The University of Wisconsin – Madison, WI
2004 – 2007 NIH Chemistry-Biology Interface (CBI) Training Grant
2003 – 2004 Wisconsin Alumni Research Foundation (WARF) Fellowship
Gustavus Adolphus College – St. Peter, MN
2003 Valedictorian (Unweighted cumulative GPA = 4.00)
2003 Hollingsworth Key Award
2002 – 2003 Chemistry Department Academic Assistant Award
2002 Barry M. Goldwater Scholar in Mathematics, Science and Engineering
2001 Gerhard Alexis Scholarship
2001 American Chemical Society Polymer Chemistry Award
2000 Freshman Chemistry Award
1999 – 2003 Partners in Scholarship Award