![Page 1: Dr. Richard Gammon OneBlood, Inc. Patient Blood Management](https://reader033.vdocuments.mx/reader033/viewer/2022061607/629f9ecad0557a01de0485d2/html5/thumbnails/1.jpg)
Patient Blood ManagementWhat you Need to Know!
Speaker Name
Dr. Richard Gammon
OneBlood, Inc.
![Page 2: Dr. Richard Gammon OneBlood, Inc. Patient Blood Management](https://reader033.vdocuments.mx/reader033/viewer/2022061607/629f9ecad0557a01de0485d2/html5/thumbnails/2.jpg)
At the end of the session, the participant will be able to:
Discuss current transfusion thresholds
Possess a basic knowledge of patient blood management
Be knowledgeable of alternatives to blood transfusion
![Page 3: Dr. Richard Gammon OneBlood, Inc. Patient Blood Management](https://reader033.vdocuments.mx/reader033/viewer/2022061607/629f9ecad0557a01de0485d2/html5/thumbnails/3.jpg)
HEADER / PRESENTATION TITLE
Current Transfusion Thresholds
![Page 4: Dr. Richard Gammon OneBlood, Inc. Patient Blood Management](https://reader033.vdocuments.mx/reader033/viewer/2022061607/629f9ecad0557a01de0485d2/html5/thumbnails/4.jpg)
Recommendation 1
• Transfusion is not indicated until the hemoglobin level is 7g/dL
• Hospitalized adult patients who are hemodynamically stable
• Including critically ill patients
• Strong recommendation, moderate quality evidence
JAMA 2016; 316: 2025-35
![Page 5: Dr. Richard Gammon OneBlood, Inc. Patient Blood Management](https://reader033.vdocuments.mx/reader033/viewer/2022061607/629f9ecad0557a01de0485d2/html5/thumbnails/5.jpg)
Recommendation 1
• Orthopedic surgery or cardiac surgery and those with preexisting cardiovascular disease
• Restrictive RBC transfusion threshold hemoglobin level of 8g/dL
• Strong recommendation, moderate quality evidence
5
JAMA 2016; 316: 2025-35
![Page 6: Dr. Richard Gammon OneBlood, Inc. Patient Blood Management](https://reader033.vdocuments.mx/reader033/viewer/2022061607/629f9ecad0557a01de0485d2/html5/thumbnails/6.jpg)
Recommendation 1 Does Not Apply
• Acute coronary syndrome
• Severe thrombocytopenia (patients treated for hematological or oncological disorders who are at risk of bleeding)
• Chronic transfusion–dependent anemia
• Evidence is insufficient for any recommendation
6
JAMA 2016; 316: 2025-35
![Page 7: Dr. Richard Gammon OneBlood, Inc. Patient Blood Management](https://reader033.vdocuments.mx/reader033/viewer/2022061607/629f9ecad0557a01de0485d2/html5/thumbnails/7.jpg)
Recommendation 2
• Patients, including neonates, should receive RBC units selected at any point within their licensed dating period (standard issue)
• Rather than limiting patients to transfusion of only fresh (storage length: <10 days) RBC units
• Strong recommendation, moderate quality evidence
7
JAMA 2016; 316: 2025-35
![Page 8: Dr. Richard Gammon OneBlood, Inc. Patient Blood Management](https://reader033.vdocuments.mx/reader033/viewer/2022061607/629f9ecad0557a01de0485d2/html5/thumbnails/8.jpg)
RBC Dosing
• Hematocrit increased 3%
• Hemoglobin increased 1 g/dL• In non-bleeding, non hemolysing
patients administered as single unit dose
• A posttransfusion H/H • Obtained within 15 minutes -
determines if additional transfusions are indicated
8
Transfusion 1997; 37: 573-76
![Page 9: Dr. Richard Gammon OneBlood, Inc. Patient Blood Management](https://reader033.vdocuments.mx/reader033/viewer/2022061607/629f9ecad0557a01de0485d2/html5/thumbnails/9.jpg)
Recommendation 1
• Prophylactically at a count 10,000/uL or less
• Reduce the risk for spontaneous bleeding
• Hospitalized adult patients
• Hypoproliferative thrombocytopenia
• Grade: strong recommendation; moderate-quality evidence
9
Ann Intern Med. 2015;162:205-213
![Page 10: Dr. Richard Gammon OneBlood, Inc. Patient Blood Management](https://reader033.vdocuments.mx/reader033/viewer/2022061607/629f9ecad0557a01de0485d2/html5/thumbnails/10.jpg)
Recommendation 2
• Prophylactic platelet transfusion for elective central venous catheter placement with platelet count less than 20,000/uL
• Grade: weak recommendation; low-quality evidence
10
www.medical-dictionary.thefreedictionary.com 09/20Ann Intern Med. 2015;162:205-213
![Page 11: Dr. Richard Gammon OneBlood, Inc. Patient Blood Management](https://reader033.vdocuments.mx/reader033/viewer/2022061607/629f9ecad0557a01de0485d2/html5/thumbnails/11.jpg)
Recommendation 3
• Prophylactic platelet transfusion for patients having elective diagnostic lumbar puncture with platelet count less than 50,000/uL
• Grade: weak recommendation; very low-quality evidence
11
www.enwikepedia.org 09/20Ann Intern Med. 2015;162:205-213
![Page 12: Dr. Richard Gammon OneBlood, Inc. Patient Blood Management](https://reader033.vdocuments.mx/reader033/viewer/2022061607/629f9ecad0557a01de0485d2/html5/thumbnails/12.jpg)
Recommendation 4
• Prophylactic platelet transfusion for patients having major elective nonneuraxial surgery with a platelet count less than 50,000/uL
• Grade: weak recommendation; very low-quality evidence
12
Ann Intern Med. 2015;162:205-213
![Page 13: Dr. Richard Gammon OneBlood, Inc. Patient Blood Management](https://reader033.vdocuments.mx/reader033/viewer/2022061607/629f9ecad0557a01de0485d2/html5/thumbnails/13.jpg)
Recommendation 5
• Cardiopulmonary bypass (CPB)
• Perioperative bleeding with thrombocytopenia and/or evidence of platelet dysfunction
• Grade: weak recommendation; very low-quality evidence
13
Ann Intern Med. 2015;162:205-213
![Page 14: Dr. Richard Gammon OneBlood, Inc. Patient Blood Management](https://reader033.vdocuments.mx/reader033/viewer/2022061607/629f9ecad0557a01de0485d2/html5/thumbnails/14.jpg)
Recommendation 6
• The AABB cannot recommend for or against platelet transfusion for patients receiving antiplatelet therapy who have intracranial hemorrhage (traumatic or spontaneous)
• Grade: uncertain recommendation; very low-quality evidence
14
Ann Intern Med. 2015;162:205-213
![Page 15: Dr. Richard Gammon OneBlood, Inc. Patient Blood Management](https://reader033.vdocuments.mx/reader033/viewer/2022061607/629f9ecad0557a01de0485d2/html5/thumbnails/15.jpg)
Active BleedingNo High-Quality Evidence for Guidance
Criteria Platelet Count (/uL)
Thrombocytopenic Bleeding Patients Often recommended maintain count above 50,000/uL
15
AABB Technical Manual 20th ed. 2020
Some facilities use 100,000/UL for ophthalmologic, neurologic and pulmonary hemorrhage
![Page 16: Dr. Richard Gammon OneBlood, Inc. Patient Blood Management](https://reader033.vdocuments.mx/reader033/viewer/2022061607/629f9ecad0557a01de0485d2/html5/thumbnails/16.jpg)
Thrombocytopathy
• Causes• Congenital (e.g., Glanzmann thrombasthenia)
• Acquired as the result of disease (e.g., myelodysplasia)
• Drug treatment (e.g., with aspirin or glycoprotein IIb/IIIa antagonists)
• Transfusion Decisions• Acceptable even at normal counts
• Based upon patient’s clinical status
• Test platelet function
AABB Technical Manual 20th ed. 2020
![Page 17: Dr. Richard Gammon OneBlood, Inc. Patient Blood Management](https://reader033.vdocuments.mx/reader033/viewer/2022061607/629f9ecad0557a01de0485d2/html5/thumbnails/17.jpg)
• Platelet count should be obtained • Before
• 10 to 60 minutes after transfusion
• Platelet count should increase by 30,000 to 60,000/uL
• Assess the adequacy of response to transfusion
Platelets-Pre and Post Counts
AABB Technical Manual 20th ed. 2020Transfusion 1988:28:66-67
![Page 18: Dr. Richard Gammon OneBlood, Inc. Patient Blood Management](https://reader033.vdocuments.mx/reader033/viewer/2022061607/629f9ecad0557a01de0485d2/html5/thumbnails/18.jpg)
AABB Clinical Practice GuidelinesPlasma Thresholds• Current evidence-based guidelines for plasma transfusion are weak
• Systematic review of the available data found it to be sparse and of low quality
• Multidisciplinary panel of 17 experts developed evidenced-based guidelines
18
Murad MH, et al. Transfusion 2010; 50:1370-83Roback JD, et al. Transfusion 2010; 50: 1227-39
![Page 19: Dr. Richard Gammon OneBlood, Inc. Patient Blood Management](https://reader033.vdocuments.mx/reader033/viewer/2022061607/629f9ecad0557a01de0485d2/html5/thumbnails/19.jpg)
Plasma - Primary Supportable Indications
•Use for massive transfusion
•Reversal of warfarin anticoagulation in patients with intracranial hemorrhage
•Another therapeutic use is with plasma exchange for treatment of thrombotic thrombocytopenic purpura (TTP)*
19
*Common use not included with indicationsMurad MH, et al. Transfusion 2010; 50:1370-83Roback JD, et al. Transfusion 2010; 50: 1227-39
![Page 20: Dr. Richard Gammon OneBlood, Inc. Patient Blood Management](https://reader033.vdocuments.mx/reader033/viewer/2022061607/629f9ecad0557a01de0485d2/html5/thumbnails/20.jpg)
Not Recommended
• Situations that have typically resulted in prophylactic plasma infusion
• Coagulopathy or bleeding was absent, the risk of lung injury and possible increased mortality outweighed benefit
20
Transfusion-Related Acute Lung Injury (TRALI)
https://groupbpart5meltech.wordpress.com/case-study-transfusion-relate-acute-lung-injury/ 09/20
Murad MH, et al. Transfusion 2010; 50:1370-83Roback JD, et al. Transfusion 2010; 50: 1227-39
![Page 21: Dr. Richard Gammon OneBlood, Inc. Patient Blood Management](https://reader033.vdocuments.mx/reader033/viewer/2022061607/629f9ecad0557a01de0485d2/html5/thumbnails/21.jpg)
Additional Plasma Indications
• Before Invasive Procedures• INR>2.0
• Congenital factor deficiencies no coagulation concentrate available
21
Blood transfusion therapy. A physician’s handbook. 12th ed. 2017 Transfusion 2006; 46:1279-85
INR 1.1-1.5 1.5-1.85
![Page 22: Dr. Richard Gammon OneBlood, Inc. Patient Blood Management](https://reader033.vdocuments.mx/reader033/viewer/2022061607/629f9ecad0557a01de0485d2/html5/thumbnails/22.jpg)
Timing and Dose of Administration
• Correction -INR, PT or PTT is required• Plasma should be given immediately before surgery
• Dose• Based upon the patient’s size
• 10 to 20 mL/kg – multiple units are acceptable
• Measurement of coagulation parameters • Before and within 5 hours after transfusion
• Factor VII has a biologic half-life of 5 hours
22
AABB Technical Manual 20th ed. 2020
![Page 23: Dr. Richard Gammon OneBlood, Inc. Patient Blood Management](https://reader033.vdocuments.mx/reader033/viewer/2022061607/629f9ecad0557a01de0485d2/html5/thumbnails/23.jpg)
Choosing Wiselyand Alternatives to Blood Transfusion
![Page 24: Dr. Richard Gammon OneBlood, Inc. Patient Blood Management](https://reader033.vdocuments.mx/reader033/viewer/2022061607/629f9ecad0557a01de0485d2/html5/thumbnails/24.jpg)
• Overuse of blood transfusion has also been listed as Choosing Wisely statement • American Society of Hematology• Society of Hospital Medicine • Critical Care Societies
Collaborative
• AABB developed set of five recommendations with input committees and Board of Directors
Choosing Wisely Program
Transfusion 2014; 54: 2344-2352
![Page 25: Dr. Richard Gammon OneBlood, Inc. Patient Blood Management](https://reader033.vdocuments.mx/reader033/viewer/2022061607/629f9ecad0557a01de0485d2/html5/thumbnails/25.jpg)
#1 Don’t transfuse more units of blood than absolutely necessary
•Restrictive threshold (7.0-8.0g/dL) should be used for vast majority of hospitalized, stable patients without evidence of inadequate tissue oxygenation
• Evidence supports threshold of 8.0g/dL in patients with existing cardiovascular disease
25
![Page 26: Dr. Richard Gammon OneBlood, Inc. Patient Blood Management](https://reader033.vdocuments.mx/reader033/viewer/2022061607/629f9ecad0557a01de0485d2/html5/thumbnails/26.jpg)
#1 Don’t transfuse more units of blood than absolutely necessary
• Transfusion decisions should be influenced by symptoms and hemoglobin (Hb) concentration
• Single unit red blood cell transfusions should be standard for nonbleeding hospitalized patients
•Additional units should only be prescribed after reassessment of patient and Hb value
26
![Page 27: Dr. Richard Gammon OneBlood, Inc. Patient Blood Management](https://reader033.vdocuments.mx/reader033/viewer/2022061607/629f9ecad0557a01de0485d2/html5/thumbnails/27.jpg)
#2 Don’t transfuse RBCs for iron deficiency without hemodynamic instability
•Blood transfusion has become routine medical response despite cheaper and safer alternatives in some settings
•Preoperative patients with iron deficiency and patients with chronic iron deficiency without hemodynamic instability (even with low Hb levels) • Oral and/or intravenous (IV) iron
27
![Page 28: Dr. Richard Gammon OneBlood, Inc. Patient Blood Management](https://reader033.vdocuments.mx/reader033/viewer/2022061607/629f9ecad0557a01de0485d2/html5/thumbnails/28.jpg)
Anemia Management
28
Benitez-Sanchez – Blood Management Workshop 11/11
![Page 29: Dr. Richard Gammon OneBlood, Inc. Patient Blood Management](https://reader033.vdocuments.mx/reader033/viewer/2022061607/629f9ecad0557a01de0485d2/html5/thumbnails/29.jpg)
Myths About Vitamin K
![Page 30: Dr. Richard Gammon OneBlood, Inc. Patient Blood Management](https://reader033.vdocuments.mx/reader033/viewer/2022061607/629f9ecad0557a01de0485d2/html5/thumbnails/30.jpg)
Intravenous vitamin K is safe
• Some clinicians (and nurses) refuse to administer vitamin K intravenously due to the risk of anaphylaxis
•Historically, product had castor oil…
•Risk:• 0.04-11/10,000 doses
Fiore et al. J Thromb Thrombolysis 2001; 11:175-83
![Page 31: Dr. Richard Gammon OneBlood, Inc. Patient Blood Management](https://reader033.vdocuments.mx/reader033/viewer/2022061607/629f9ecad0557a01de0485d2/html5/thumbnails/31.jpg)
Slow to Reverse Warfarin
• Observation of effect of vitamin K on the international normalized ratio (INR) when administered subcutaneously
• Fat-soluble compound, subcutaneous injection slows absorption due to its solubility in subcutaneous fat
• Route of administration is least effective
• Effectively reverses the INR when given intravenously (IV) or orally
31
Overuse of plasma transfusion. ASCP Webinar 05/08/13Transfusion 2012;52:45S-55S
Arch Intern Med 1999;159:2721-4.Ann Intern Med 2002;137:251-4
Arch Intern Med 2003;163:2469-73
![Page 32: Dr. Richard Gammon OneBlood, Inc. Patient Blood Management](https://reader033.vdocuments.mx/reader033/viewer/2022061607/629f9ecad0557a01de0485d2/html5/thumbnails/32.jpg)
When should you consider reversing with a blood product?
• Limb or life-threatening bleeding• Intracranial hemorrhage
• Pericardial bleed
• Emergency surgical procedure in the next 6 hours• Traumatic rupture of a spleen, perforated viscous, ruptured
aneurysm
• Not just because the surgeon has operating room time in one hour
Transfusion 2012;52:45S-55S
![Page 33: Dr. Richard Gammon OneBlood, Inc. Patient Blood Management](https://reader033.vdocuments.mx/reader033/viewer/2022061607/629f9ecad0557a01de0485d2/html5/thumbnails/33.jpg)
#4 Don’t perform serial blood counts on clinically stable patients• Blood counts
• Reason to believe that new clinically significant abnormality will be detected
• Stable patients• Serial blood counts are
unlikely to detect clinically significant abnormalities
• Contribute to iatrogenic anemia
33
![Page 34: Dr. Richard Gammon OneBlood, Inc. Patient Blood Management](https://reader033.vdocuments.mx/reader033/viewer/2022061607/629f9ecad0557a01de0485d2/html5/thumbnails/34.jpg)
Study 1- Cardiac Surgery PatientsSingle Center Study
• January 1, 2012 to June 30, 2012
• 1,894 patients underwent cardiac surgery • 1,867 - 1 hospitalization
• 27 – 2 hospitalizations
• Phlebotomy volume was estimated separately • Intensive care unit (ICU)
• Hospital floors
• Cumulatively
34
Ann Thorac Surg 2015; 99: 779-85
![Page 35: Dr. Richard Gammon OneBlood, Inc. Patient Blood Management](https://reader033.vdocuments.mx/reader033/viewer/2022061607/629f9ecad0557a01de0485d2/html5/thumbnails/35.jpg)
Increasing length of stay was associated with increasing overall phlebotomy volume and red blood cell transfusion
35
![Page 36: Dr. Richard Gammon OneBlood, Inc. Patient Blood Management](https://reader033.vdocuments.mx/reader033/viewer/2022061607/629f9ecad0557a01de0485d2/html5/thumbnails/36.jpg)
Study Conclusions
• During the length of stay
• Patient’s total phlebotomy volumes approached amounts equivalent to 1 to 2 red blood cell units
![Page 37: Dr. Richard Gammon OneBlood, Inc. Patient Blood Management](https://reader033.vdocuments.mx/reader033/viewer/2022061607/629f9ecad0557a01de0485d2/html5/thumbnails/37.jpg)
Study 2 – Hospital Blood Loss
• All patients discharged 2012-2014
• Cumulative daily blood volume and draw frequency were reported by service and days since admission
• Changes in Hb and red blood cell transfusion rates were reported for nontransfused and transfused patients
Transfusion 2019;59;2849–2856
![Page 38: Dr. Richard Gammon OneBlood, Inc. Patient Blood Management](https://reader033.vdocuments.mx/reader033/viewer/2022061607/629f9ecad0557a01de0485d2/html5/thumbnails/38.jpg)
Results
• 59,715 subjects
• Mean daily estimated blood loss varied from 8.5-27.2 mL/day (ICU; p < 0.001)
• Phlebotomy volumes highest on first day of admission and declined thereafter (p < 0.001)
![Page 39: Dr. Richard Gammon OneBlood, Inc. Patient Blood Management](https://reader033.vdocuments.mx/reader033/viewer/2022061607/629f9ecad0557a01de0485d2/html5/thumbnails/39.jpg)
Results
• First week of admission, Hb levels decreased by highest percentage in ICU
• Rate of RBC transfusion highest in ICU
• 232.4 units/1000 patient-days
• p < 0.0001 compared with all other locations
![Page 40: Dr. Richard Gammon OneBlood, Inc. Patient Blood Management](https://reader033.vdocuments.mx/reader033/viewer/2022061607/629f9ecad0557a01de0485d2/html5/thumbnails/40.jpg)
Conclusions
•Considerable variation observed in estimated blood loss due to diagnostic phlebotomy across different services within one teaching hospital
• Foundation for planning interventions to minimize estimated blood loss from phlebotomy
![Page 41: Dr. Richard Gammon OneBlood, Inc. Patient Blood Management](https://reader033.vdocuments.mx/reader033/viewer/2022061607/629f9ecad0557a01de0485d2/html5/thumbnails/41.jpg)
#5. Don’t transfuse O– blood
•Recommended group O Rh(D)-negative RBCs should be reserved for group O Rh(D)-negative patients and in emergencies to females of childbearing potential
•Recent study estimated 44.5% of group O Rh(D)-negative RBC units used could have been replaced by group O Rh(D)-positive RBC units if age and gender factors were considered
Transfusion 2014, 54: 2344-2352Transfusion 2018;58: 1348-55
AABB Association Bulletin 19-02
![Page 42: Dr. Richard Gammon OneBlood, Inc. Patient Blood Management](https://reader033.vdocuments.mx/reader033/viewer/2022061607/629f9ecad0557a01de0485d2/html5/thumbnails/42.jpg)
Patient Blood ManagementThe Basics
![Page 43: Dr. Richard Gammon OneBlood, Inc. Patient Blood Management](https://reader033.vdocuments.mx/reader033/viewer/2022061607/629f9ecad0557a01de0485d2/html5/thumbnails/43.jpg)
Which Best Describes the Patient Blood Management Program At Your Hospital?
43
Jadwin D, et al. AABB 10/17
![Page 44: Dr. Richard Gammon OneBlood, Inc. Patient Blood Management](https://reader033.vdocuments.mx/reader033/viewer/2022061607/629f9ecad0557a01de0485d2/html5/thumbnails/44.jpg)
Patient Blood Management Covers Vein to Vein
44ABC Webinar 02/26/2014
![Page 45: Dr. Richard Gammon OneBlood, Inc. Patient Blood Management](https://reader033.vdocuments.mx/reader033/viewer/2022061607/629f9ecad0557a01de0485d2/html5/thumbnails/45.jpg)
Program Evolution
S. Benitez- Santana. Blood Management Summit 11/10
![Page 46: Dr. Richard Gammon OneBlood, Inc. Patient Blood Management](https://reader033.vdocuments.mx/reader033/viewer/2022061607/629f9ecad0557a01de0485d2/html5/thumbnails/46.jpg)
Cost of Allogeneic Blood
Transfusion 2010; 50: 753-65Transfusion 2018;58;846–853
![Page 47: Dr. Richard Gammon OneBlood, Inc. Patient Blood Management](https://reader033.vdocuments.mx/reader033/viewer/2022061607/629f9ecad0557a01de0485d2/html5/thumbnails/47.jpg)
What is Patient Blood Management??
• AABB- Patient Blood Management is the evidence-based multidisciplinary approach to optimizing the care of patients who may need transfusion
• SABM - Timely application of evidenced-based medical and surgical concepts designed to maintain hemoglobin concentration, optimize hemostasis, and minimize blood loss in an effort to improve patient outcomes
Transfusion Medicine’s Emerging Positions- AABB Press 2013
![Page 48: Dr. Richard Gammon OneBlood, Inc. Patient Blood Management](https://reader033.vdocuments.mx/reader033/viewer/2022061607/629f9ecad0557a01de0485d2/html5/thumbnails/48.jpg)
Getting StartedEstablish Working Group
•Medical director
•Blood Bank Supervisor
• Lab Director
• Transfusion Safety Officer
•Administration
•Quality Assurance
48
![Page 49: Dr. Richard Gammon OneBlood, Inc. Patient Blood Management](https://reader033.vdocuments.mx/reader033/viewer/2022061607/629f9ecad0557a01de0485d2/html5/thumbnails/49.jpg)
Establish Patient Blood Management StructureQuality
Council/Medical Executive Committee
Chief Medical Officer
Transfusion Safety Officer
Patient Blood Management
Committee
PBM Working Group
Massive Transfusion Review Committee
Medical Director
![Page 50: Dr. Richard Gammon OneBlood, Inc. Patient Blood Management](https://reader033.vdocuments.mx/reader033/viewer/2022061607/629f9ecad0557a01de0485d2/html5/thumbnails/50.jpg)
Review Polices and Procedures and Computer Order Entry (CPOE) Systems
50
≠
![Page 51: Dr. Richard Gammon OneBlood, Inc. Patient Blood Management](https://reader033.vdocuments.mx/reader033/viewer/2022061607/629f9ecad0557a01de0485d2/html5/thumbnails/51.jpg)
Enforce the Policies
• Alert physician letters are coming
• Informational for 6 months
• Medical Executive/Quality Council Committee decide how many nonconformities to elevate to additional action
51
Fillable fields, email responsessend monthly
![Page 52: Dr. Richard Gammon OneBlood, Inc. Patient Blood Management](https://reader033.vdocuments.mx/reader033/viewer/2022061607/629f9ecad0557a01de0485d2/html5/thumbnails/52.jpg)
What To Measure
• Transfusion documentation
• Site audits
• Discharge instructions
• Task responses-follow-up
• Transfusion thresholds
• Wastage
• RBC per 1000 patient days
• Massive Transfusion Protocol
• Single unit Red Blood Cells
• Single unit Plasma
• Discharge Hemoglobin
• Failure to transfuse when indicated
• Product trends
• Transfusion reactions
• Clinical decision support data-cancelled orders
![Page 53: Dr. Richard Gammon OneBlood, Inc. Patient Blood Management](https://reader033.vdocuments.mx/reader033/viewer/2022061607/629f9ecad0557a01de0485d2/html5/thumbnails/53.jpg)
Transfusion Documentation
• Informed consent – fully completed -signed, witnessed, time/date
• Start/stop date/time
• Transfusionist/verifier
• Rate of infusion
• Volume transfused
• Vital signs at start, 15 min, end
• Pre-transfusion documentation
• Transfusion time (greater than 4 hours)
![Page 54: Dr. Richard Gammon OneBlood, Inc. Patient Blood Management](https://reader033.vdocuments.mx/reader033/viewer/2022061607/629f9ecad0557a01de0485d2/html5/thumbnails/54.jpg)
The Numbers – Transfusion Documentation
![Page 55: Dr. Richard Gammon OneBlood, Inc. Patient Blood Management](https://reader033.vdocuments.mx/reader033/viewer/2022061607/629f9ecad0557a01de0485d2/html5/thumbnails/55.jpg)
Discharge Instructions
![Page 56: Dr. Richard Gammon OneBlood, Inc. Patient Blood Management](https://reader033.vdocuments.mx/reader033/viewer/2022061607/629f9ecad0557a01de0485d2/html5/thumbnails/56.jpg)
Nursing Task Responses
![Page 57: Dr. Richard Gammon OneBlood, Inc. Patient Blood Management](https://reader033.vdocuments.mx/reader033/viewer/2022061607/629f9ecad0557a01de0485d2/html5/thumbnails/57.jpg)
Transfusion Thresholds
![Page 58: Dr. Richard Gammon OneBlood, Inc. Patient Blood Management](https://reader033.vdocuments.mx/reader033/viewer/2022061607/629f9ecad0557a01de0485d2/html5/thumbnails/58.jpg)
Wastage
0
5
10
15
20
25
30
35
40
Jan Feb Mar Apr May Jun July Aug Sept Oct Nov Dec Jan Feb Mar Apr May Jun
Un
its
Wasted Products 2019
Red Blood Cells
Plasma
Platelets
Cryo
![Page 59: Dr. Richard Gammon OneBlood, Inc. Patient Blood Management](https://reader033.vdocuments.mx/reader033/viewer/2022061607/629f9ecad0557a01de0485d2/html5/thumbnails/59.jpg)
Martin North Martin South Martin Tradition
January 38.19 43.95 31.71
February 37.69 63.44 39.22
March 37.19 45.08 36.87
April 39.59 62.10 44.34
May 33.09 52.56 35.97
June 33.73 48.46 32.81
0.00
10.00
20.00
30.00
40.00
50.00
60.00
70.00
2020 CMI-weight Red Blood Cells 1K Acute Patient Days
January
February
March
April
May
June
![Page 60: Dr. Richard Gammon OneBlood, Inc. Patient Blood Management](https://reader033.vdocuments.mx/reader033/viewer/2022061607/629f9ecad0557a01de0485d2/html5/thumbnails/60.jpg)
Single Unit Red Blood Cells
• Percentage based off orders with hgb greater than 6• Screensaver month long launches: Oct 2017, Jan, Mar, Sept 2018, May, June, July 2019, Feb 2020 – blue arrows
• Goal is 60%- green line
2018- 55.41%2019- 62.25%2020-63.7%
![Page 61: Dr. Richard Gammon OneBlood, Inc. Patient Blood Management](https://reader033.vdocuments.mx/reader033/viewer/2022061607/629f9ecad0557a01de0485d2/html5/thumbnails/61.jpg)
Single Unit Plasma
• May and June 2020 COVID-19 Convalescent Plasma
• Includes single unit plasma for angioedema
![Page 62: Dr. Richard Gammon OneBlood, Inc. Patient Blood Management](https://reader033.vdocuments.mx/reader033/viewer/2022061607/629f9ecad0557a01de0485d2/html5/thumbnails/62.jpg)
Product Trends
![Page 63: Dr. Richard Gammon OneBlood, Inc. Patient Blood Management](https://reader033.vdocuments.mx/reader033/viewer/2022061607/629f9ecad0557a01de0485d2/html5/thumbnails/63.jpg)
Clinical Decision Support
• Displayed last three applicable labs
• First bullet of applicable transfusion threshold SOPs and link to full SOP
• Ask clinician if wanted to continue with order and gave option to cancel
63
![Page 64: Dr. Richard Gammon OneBlood, Inc. Patient Blood Management](https://reader033.vdocuments.mx/reader033/viewer/2022061607/629f9ecad0557a01de0485d2/html5/thumbnails/64.jpg)
Site Audits
• Issued from lab per policy
• Matched with order
• Completed Consent
• IV NaCl/blood tubing
• Two nurses compare/match and readback all identifiers
• Initiated within 30 min
• Form attached to component
• Vital signs at pre, 15 min, end
• Verification with two signatures
• Infused within 4 hours
• Lab values meet criteria
![Page 65: Dr. Richard Gammon OneBlood, Inc. Patient Blood Management](https://reader033.vdocuments.mx/reader033/viewer/2022061607/629f9ecad0557a01de0485d2/html5/thumbnails/65.jpg)
Site Audits/Floor Visits
![Page 66: Dr. Richard Gammon OneBlood, Inc. Patient Blood Management](https://reader033.vdocuments.mx/reader033/viewer/2022061607/629f9ecad0557a01de0485d2/html5/thumbnails/66.jpg)
Tracer Audits are Important
• The Joint Commission Resources (tracer software)
• Deficiency noted – email sent and request required by specified date
• Monthly meetings with Nursing Leadership• Follow-up on responses
where questions are not complete
• Provide PBM update
![Page 67: Dr. Richard Gammon OneBlood, Inc. Patient Blood Management](https://reader033.vdocuments.mx/reader033/viewer/2022061607/629f9ecad0557a01de0485d2/html5/thumbnails/67.jpg)
Nursing Response Rate - Percent
![Page 68: Dr. Richard Gammon OneBlood, Inc. Patient Blood Management](https://reader033.vdocuments.mx/reader033/viewer/2022061607/629f9ecad0557a01de0485d2/html5/thumbnails/68.jpg)
Patient Blood Management CommitteeOnly as Good as Its Members• Chair – Sets direction of PBM at
Medical Center• Transfusion Safety Officer• Blood Bank Supervisor• Laboratory Director• Administrator• Quality Assurance• Laboratory Transfusion Service
Pathologist • Hematology/Oncology • Risk Management
• Surgery • Anesthesia • Obstetrics/Gynecology • Hospitalist • Nephrology • Emergency Department• Neonatology• Marketing• Inpatient Care• Information Technology
68
![Page 69: Dr. Richard Gammon OneBlood, Inc. Patient Blood Management](https://reader033.vdocuments.mx/reader033/viewer/2022061607/629f9ecad0557a01de0485d2/html5/thumbnails/69.jpg)
Reduction in Blood - PBM approach
•Number of transfusions given per number of patient admissions
• Since initiation of PBM program in August 2014
•Reduction of 41% in rate of transfusions
![Page 70: Dr. Richard Gammon OneBlood, Inc. Patient Blood Management](https://reader033.vdocuments.mx/reader033/viewer/2022061607/629f9ecad0557a01de0485d2/html5/thumbnails/70.jpg)
PBM CertificationEstablish a Timeline
Year Goals Other items
One Establish PBM Program
Two Prepare for TJC/AABB PBM Certification
Budget for certification for year three
Three Obtain TJC/AABB PBM Certification
![Page 71: Dr. Richard Gammon OneBlood, Inc. Patient Blood Management](https://reader033.vdocuments.mx/reader033/viewer/2022061607/629f9ecad0557a01de0485d2/html5/thumbnails/71.jpg)
Partner with Quality Gap Analysis
![Page 72: Dr. Richard Gammon OneBlood, Inc. Patient Blood Management](https://reader033.vdocuments.mx/reader033/viewer/2022061607/629f9ecad0557a01de0485d2/html5/thumbnails/72.jpg)
PBM Timeline
2014 Patient Blood
Management program kick-
off
Developed auditing process
Updated CPOE to
match SOPs
Implemented CDS system (last 3 labs and link
to SOPs)
2015 Massive Transfusion
Protocol
Discharge instructions
automatically printed at
time consent generated
July 2016 Patient Blood Management Educational
Video
Bloodless Medicine Program
August 2017 Single Unit Transfusion Campaign
2018 Preparing for TJC PBM Certification
survey
PBM Metrics Summer
2018
![Page 73: Dr. Richard Gammon OneBlood, Inc. Patient Blood Management](https://reader033.vdocuments.mx/reader033/viewer/2022061607/629f9ecad0557a01de0485d2/html5/thumbnails/73.jpg)
Outcome
Few hospital systems
achieve this prestigious
Award!
73
![Page 74: Dr. Richard Gammon OneBlood, Inc. Patient Blood Management](https://reader033.vdocuments.mx/reader033/viewer/2022061607/629f9ecad0557a01de0485d2/html5/thumbnails/74.jpg)
What Worked
• Prepared for day of survey
• Provided opening presentation
• Followed agenda
• Surveyors/Assessors knowledgeable and professional
74
![Page 75: Dr. Richard Gammon OneBlood, Inc. Patient Blood Management](https://reader033.vdocuments.mx/reader033/viewer/2022061607/629f9ecad0557a01de0485d2/html5/thumbnails/75.jpg)
Know the Lingo
75
Assessment SurveyNonconformance Requirement for Improvement
Assessor Surveyor
![Page 76: Dr. Richard Gammon OneBlood, Inc. Patient Blood Management](https://reader033.vdocuments.mx/reader033/viewer/2022061607/629f9ecad0557a01de0485d2/html5/thumbnails/76.jpg)
What Did Not Work
• No documented evidence that staff attended educational opportunities that had been provided by Patient Blood Management
• Inconsistent understanding of goals and objectives of program
76
![Page 77: Dr. Richard Gammon OneBlood, Inc. Patient Blood Management](https://reader033.vdocuments.mx/reader033/viewer/2022061607/629f9ecad0557a01de0485d2/html5/thumbnails/77.jpg)
Facility Awareness is Important
• Ensure staff is aware of program
• Incorporated into annual physician and nursing education
![Page 78: Dr. Richard Gammon OneBlood, Inc. Patient Blood Management](https://reader033.vdocuments.mx/reader033/viewer/2022061607/629f9ecad0557a01de0485d2/html5/thumbnails/78.jpg)
Current Status
•Re-certification survey originally scheduled for 3Q20
•Date of survey to be determined
•May be virtual
•Happy 6th birthday!78
![Page 79: Dr. Richard Gammon OneBlood, Inc. Patient Blood Management](https://reader033.vdocuments.mx/reader033/viewer/2022061607/629f9ecad0557a01de0485d2/html5/thumbnails/79.jpg)
The Last Pandemic -1918
79
America’s Pastime Outdoor Court
![Page 80: Dr. Richard Gammon OneBlood, Inc. Patient Blood Management](https://reader033.vdocuments.mx/reader033/viewer/2022061607/629f9ecad0557a01de0485d2/html5/thumbnails/80.jpg)
The Last Pandemic -1918
80
First Responders
![Page 81: Dr. Richard Gammon OneBlood, Inc. Patient Blood Management](https://reader033.vdocuments.mx/reader033/viewer/2022061607/629f9ecad0557a01de0485d2/html5/thumbnails/81.jpg)
SESSION NUMBER
4805