Download - Cortical Anatomy
Cortical Anatomy
A systems approach
http:/da.biostr.washington.edu/da.html
Overview
• Orientation to the brain• Visual systems- recognition and higher level
processing• “where” systems, parietal lobe functions• Language systems, reading• Frontal lobe systems• Memory systems: HC and BG• Social and emotional systems
Lobar Anatomy
CS
IFG
MFGSFG M1
S1
IPL
SMG AG SO
IO
ST
MT
IT
Dorsal View
SFS
SPL
M1
S1
IPS
SFG
Insula and TTG
Medial ViewMedial FGGFD 6
Cingulate 32, 24
P-O
Calcarine
Inf OG
Sup OG
Mid OG
Retrosplenial Cortex 30
PCL Precuneus
31,23
Ventral View, limbic system exposed
Orbital 11,47
Gyrus rectus 11/12
PHG 36
Lingual 17-19
Fusiform 37
ERC 28/34
Subcortical regions
CaudatePutamenGlobus pallidusthalamus
Brodmann’s maps
Visual system
Visual Pathway
Retinotopy: Background
STL38, 22
MTL 21ITL 20
IPLSMG 40/AG 39
OCC19 18
O-TFUSIFORM37
Visual System- what vs where
Levy et al.: Methods
Stimuli: Faces, houses; center, periphery
Visual System- what vs where
Parietal cortex and spaceCS IPS
IPS
Fronto-parietal attention/Working memory
networksIPSDLPFC
IPS
FEF
Ventral PFC- regulation, response inhibition
Lateral, Medial OFC
Relational Complexity testRelational Complexity test
Kroger, Sabb, Fales, Bookheimer, Cohen, Holyoak 2002
Distractor Control
LH Language System
A1, A2 41,42 Heschls
38: high levelCategorical rep
20/37 Basal temporal naming area
22/21Auditory comp“Wernicke’s
39 AGAud/visIntegrationincludingreading
40 SMG phoneme sequencing
SSMA (medial) 6
Exner’s areawriting
IFG44,45,47(see next slide)
Auditory cortex activation with
speech
Frontal language areas
4 56 6
8
6 9
1010
9
IFG dissociations
47 Orbitalis: Semantic integration
45 triangularissyntax
44 opercularisPhonology, sequencing
Orbital frontal cortex: 47/45• Arguments about its job: semantics; verbal
selection; selection generally• Integration of (semantic) information• Lesion/electrical stimulation: semantic
integration deficits: normal object naming, grammatic speech; impaired auditory responsive naming
4
Ventral View, limbic system exposed
Orbital 11,47
Gyrus rectus 11/12
PHG 36
Lingual 17-19
Fusiform 37
ERC 28/34
Facial Emotions “Match” “Label” Control
Match Expressions: Perception only; implicit emotional processingLabel Expressions: Explicit cognitive analysis
Match Affect- normal adults
Hariri et al., 1999
amygdala
face area
-seeing negative face expressions activates Face and Fear brain centers
Label Affect
Hariri et al., 1999
amygdala
-interpreting negative face expressions activates Face brain center …
Cortical Influence During “Label”
Hariri et al., 1999
-this frontal lobe region regulates and controls Fear brain centers
Memory systems: hippocampus
Hippocampal Circuitry
PRC
PHG
ERC
Sub
DG CA 3
CA 1
fornix
Anterior Posterior
Known by tracer studies in monkeys, rats, and the cat.
QuickTime™ and aTIFF (Uncompressed) decompressorare needed to see this picture.
Enough neuroanatomy for one day
A
B
M1 tongue
Medial PMC M1 hand
Insular motor,Sensory cortex
Surface
M1 4 S1 213SFG 6,8,10,11
MFG 9, 10, 46
IFG 4445, 47
LPMC 6
Temporal/OccipitalJunction
Superior TemporalGyrus (posterior)
Angular Gyrus
Supramarginal Gyrus
Inferior FrontalGyrus
Brain Regions in Reading