division researcher type sponsor 2007 title ......samples from clinical trial protocols a4001027,...
TRANSCRIPT
UBC Department of Medicine Page 1 Annual Report 2007
DIVISION RESEARCHER TYPE SPONSOR 2007 FUNDING
TITLE
AIDS Harrigan Agreement Pfizer Ltd (UK)
206,710 Samples from Clinical Trial Protocols A4001027, A4001028, and A4001029 of Compound UK-427,857
AIDS Harrigan Clinical Trial Pfizer Canada Inc. 1,050,000
HIV Co-receptor Usage Assay by Quantitative Population...
AIDS Harrigan Grant Abbott Laboratories Ltd. (Canada) 327,478
Abbott/BC-CfE Research Support and Collaboration Agreement
AIDS Kerr Grant CIHR Operating Grant MOP-81171 54,700
Exploring the natural history of injection drug use: A qualitative study of social and environmental influences
AIDS Kerr Grant MSFHR Scholar Award CI-SCH-085(05-1) HSR
45,000
An investigation of injection drug use and HIV infection among drug using youth
AIDS Kerr Grant MSFHR Establishment Grant CI-SCH-085(05-1)
75,000
An investigation of injection drug use and HIV infection among drug using youth
AIDS Kerr Grant CIHR: HIV/AIDS Research Program CBR-79873
90,973
Evaluating a peer-driven safer injecting education program
AIDS Kerr Grant MSFHR Matching Establishment Grant CI-SCH-085(05-1)
50,000
An investigation of injection drug use and HIV infection among drug-using youth
AIDS Kerr Grant CIHR New Investigator MSH-80536 58,500
An investigation of injection drug use and HIV infection among drug-using youth
AIDS Kerr Grant CIHR Operating Grant RAA-79918 167,568
Vancouver multi-disciplinary collaboration of injection drug use researchers
AIDS Montaner Clinical Trial Abbott Laboratories Ltd. (Canada) 2,120
Protocol M06-802 (version 1.0): A Phase 3, Randomized, Open Label Study of Lopinavir/Ritonavir Tablets 800/200mg Once-Daily Versus 400/100mg Twice-Daily When Co-administered With Nucleoside/Nucleotide Reverse Transcriptase Inhibitors in Ant
AIDS Montaner Grant CIHR Fellowship (HIV/AIDS) - Health Services/Population Health Stream ZNF-84404 (Fellow: Lima, Viviane Dias)
5,000
Research Allowance: Longitudinal impact of adherence on HIV/AIDS disease progression: implications for interventions
AIDS Montaner Grant CIHR Fellowship (HIV/AIDS) - Health Services/Population Health Stream ZNF-84404 (Fellow: Lima, Viviane Dias)
33,333
Salary: Longitudinal impact of adherence on HIV/AIDS disease progression: implications for interventions
AIDS Montaner Clinical Trial Merck Frosst Canada Ltd. 3,000
Protocol 023-00 (MK-0518 Early Access): Early Access of MK-0518 in Combination With an Optimized Background Antiretroviral Therapy (OBT) in Highly Treatment Experienced HIV-1 Infected Patients With Limited to No Treatment Options
UBC Department of Medicine Page 2 Annual Report 2007
AIDS Montaner Grant Abbott Laboratories Ltd. (Canada) 52,670
A06-320
AIDS Montaner Clinical Trial TheraTechnologies Inc. 8,000
Protocol TH9507-CTR-1011: A Multicenter, Double-Blind, Randomized, Placebo-Controlled Study Assessing the Efficacy and Safety of a 2mg Dose of TH9507, A Growth Hormone Releasing Factor Analog, in HIV Subjects With Excess Abdominal Fat…
AIDS Montaner Clinical Trial University of New South Wales 10,000
Protocol Altair: A Randomised Open-Label Study Comparing the Safety and Efficacy of Three Different Combination Antiretroviral Regimens as Initial Therapy for HIV Infection
AIDS Montaner Clinical Trial Tibotec Pharmaceuticals Ltd. 33,600
Protocol TMC125-C214 (EAP) Version 1.1: Early Access of TMC125 in Combination With Other Antiretrovirals in Treatment Experienced HIV-1 Infected Subjects With Limited Treatment Options
AIDS Montaner Grant Janssen-Ortho Inc. 10,000
Fellowship for Dr. Mark Hull: Dual-boosted protease inhibitors
AIDS Montaner Grant Janssen-Ortho Inc. 100,000
Grant BC CFE
AIDS Montaner Clinical Trial GlaxoSmithKline (Canada) Inc. 62,360
IICT: Study Evaluating the Frequency and Factors Associated with Osteoporosis in the HAART Era
AIDS Montaner Clinical Trial Merck and Co. Inc. 5,894
Protocol 0518-019 - A Multicenter, Double-Blind, Randomized, Placebo-Controlled Study to Evaluate the Safety and Antiretroviral Activity of MK-0518 in Combination With an Optimized Background Therapy (OBT), Versus Optimized Background Thera
AIDS Montaner Clinical Trial Abbott Laboratories Ltd. (Canada) 71,881
IICT: Evaluating treatment options in dyslipidemic HIV+ patients on PI-based HAART: Population-based Analysis
AIDS Montaner Clinical Trial Tibotec Pharmaceuticals Ltd. 4,203
(TMC125-C216) A Phase III Randomized, Double-blind, Placebo-controlled Trial to Investigate the Efficacy, Tolerability and Safety of TMC125 as part of an ART Including TMC114/RTV and an Investigator-selected OBR Regimen in HIV-1 Infected Patients…
AIDS Montaner Clinical Trial Pfizer Canada Inc. 12,930
(A4001027) A Multicenter, Randomized, Double-blind, Placebo- controlled Trial of a Novel CCR5 Antagonist, UK-427,857, n Combination with Optimized Background Therapy vs. Optimized Background Therapy Alone for the Treatment of Antiretroviral…
AIDS Wood Grant National Institutes of Health - Research Grant
463,866
Impacts of Universal Access to HIV/AIDS Care Among HIV+ Injection Drug Users
AIDS Wood Grant National Institutes of Health - Research Grant
504,207
Evaluating the natural history of injection drug use
UBC Department of Medicine Page 3 Annual Report 2007
AIDS Wood Grant CIHR Operating Grant HHP-67262 155,189
Investigating and addressing barriers to human immunodeficiency virus (HCV) and Hepatitis C Virus (HCV) care among injection drug users
AIDS Wood Grant CIHR: Postdoctoral Fellowship HPF-81715 (Fellow: Stoltz, Jo-Anne)
40,000
Salary: An investigation of the impact of trauma and crystal methamphetamine use on injection drug use and HIV infection among drug-using youth
AIDS Wood Grant CIHR: Postdoctoral Fellowship HPF-81715 (Fellow: Stoltz, Jo-Anne)
5,000
Research Allowance: An investigation of the impact of trauma and crystal methamphetamine use on injection drug use and HIV infection among drug-using youth
AIDS Wood Grant CIHR Operating Grant HHP-67262 158,355
The Vancouver injection drug user's study: A programme of study of HIV and Hepatitis C and other harms related to injection drug use
Allergy & Immunology
Kanani Grant Bayer HealthCare Biological Products Division
123,025
A Pilot Study of Quality of Life, Mood, Sleepiness, and Fatigue in Patients With Primary Immune Deficiency Receiving Intravenous Immunoglobulin (IVIG)
Allergy & Immunology
Stark Clinical Trial Talecris Biotherapeutics Inc. 26,758
Protocol 060001 (Talecris SC-IG): An Open-Label Single-Sequence, Crossover Trial to Evaluate the Pharmacokinetics, Safety and Tolerability of Subcutaneous Gamunex(R) 10% in Subjects with Primary Immunodeficiency (PID)
Allergy & Immunology
Schellenberg Grant Various Sources 20,000
Various sources
Cardiology Aymong Clinical Trial The Medicines Co.
10,325 The ACUITY Trial: A randomized comparison of Angiomas (bivalirudin) vs. Lovenox/Clexane (enoxaparin) in patients undergoing early invasive management for acute coronary syndromes without ST-segment elevation
Cardiology Aymong Clinical Trial National Institutes of Health 20,425
IICT: Future Revascularization Evaluation in Patients with Diabetes Mellitus: Optimal Management of Multivessel Disease (FREEDOM Trial)
Cardiology Aymong Grant Vancouver Coastal Health Authority 6,410
A double blind, randomized trial of abbreviated versus prolonged infusion of eptifibatide following successful coronary stenting (a.k.a. BRIEF)
Cardiology Aymong Clinical Trial AstraZeneca Canada Inc. 4,240
Comparison of the Effects Noted in the ApoB/ApoA-I Ration Using Rosuvastatin and Atorvastin in Patients with Acute Coronary Syndrome - CENTAURUS
Cardiology Aymong Clinical Trial Schering-Plough International 300
EARLY ACS: Early Glycoprotein IIb/IIIa Inginitionin Non-ST-segment Elevation Acute Coronary Syndrome: A Randomized, Placebo-controlled Trial Evaluating the Clinical Benefits of Early Front-loaded Eptifibatide in the Treatment of Patients with...
UBC Department of Medicine Page 4 Annual Report 2007
Cardiology Aymong Clinical Trial Eli Lilly and Co. 705
A Comparison of Prasugrel (CS-747) and Clopidogrel in Acute coronary Syndrome Subjects Who Are to Undergo Percutaneous Coronary Intervention/TIMI-38
Cardiology Bernstein Clinical Trial Servier Canada 12,736
CL3-16257-056: Effects of Ivabradine on Cardiovascular Events in Patients with Stable Coronary Artery Disease and Left Ventricular Systolic Dysfunction. A Three-Year Randomised Double-Blind Placebo-Controlled International Multicentre Sty
Cardiology Bernstein Grant Various Pharmaceutical Companies 96,000
Cardiology Research
Cardiology Bernstein Agreement Sanofi-Aventis 3,439
AUDITOR STUDY - Randomized, Multicenter, Double-Blind, Placebo-Controlled, Two-Arm Parallel Group Trial of Rimonabant 20mg, for Inhibition of Atherosclerosis Progression Assessed by Carotid Artery Intima-Media Thickness, in overweight patients…
Cardiology Bernstein Clinical Trial Hamilton Health Sciences Corporation
8,560
ONTARGET: Ongoing Telmisartan Alone and in Combination with Ramipril Global Endpoint Trial
Cardiology Bernstein Agreement Sanofi-Aventis 15,695
RIMONR00961: A Pan-European Randomized, Parallel Group, Two-arm, Placebo-controlled, Double-blind, Multicenter Study of Rimonabant 20mg Once Daily in the Treatment of Abdominally Obese Patients with Impaired Fasting Blood Glucose with or without…
Cardiology Bernstein Clinical Trial National Institutes of Health 6,882
IICT: STICH 6400: Surgical Treatment for Ischemic Heart Failure
Cardiology Bernstein Clinical Trial Canadian Institutes of Health Research
600
AF-CHF: Atrial Fibrillation and Congestive Heart Failure
Cardiology Buller Clinical Trial National Institutes of Health 2,486
IICT: Cardiovascular Outcomes in Renal Atherosclerotic Lesions (CORAL)
Cardiology Buller Agreement Abbott Vascular Devices 3,270
Zomaxx II Study: A Randomized Controlled Trial to Evaluate the Safety and Efficacy of the ZoMaxx drug Eluting Coronary Stent System as compared to the Taxus Express Paclitaxel-Eluting Stent in de-novo Coronary Artery Lesions
Cardiology Buller Agreement Schering-Plough Research Institute 36,522
TRANSCENDENCE-PCI: A Multicentre, Randomized, Double-blind, Placebo-controlled Study to Evaluate the Safety of SCH530348 in Subjects Undergoing Non-Urgent Percutaneous Coronary Intervention
Cardiology Buller Clinical Trial Cordis Corp. 128,412
1525004 ACROSS-Cypher: Approaches to Chronic Occlusions with Sirolimus Stents-Cypher - Total Occlusion Study of Coronary Arteries 4
Cardiology Buller Agreement Edwards Life sciences LLC 53,201
EVOLUTION - Clinical Evaluation of the Edwards Lifesciences Percutaneous Mitral Annuloplasty System for the treatment of Mitral Regurgitation
UBC Department of Medicine Page 5 Annual Report 2007
Cardiology Buller Clinical Trial Boston Scientific Corp. 2,500
TAXUS ATLAS: Multicenter Single-Arm Study of the TAXUS Liberte-SR Stent for the Treatment of Patients with De Novo Coronary Artery Lesions
Cardiology Buller Clinical Trial Takeda Global Research and Development
23,258
01-01-TL-OPI-516 - PERISCOPE: Double-Blind Randomized Comparator-Controlled Study in Subjects With Type 2 Diabetes Mellitus Comparing the Effects of Pioglitazone HCL vs Glimepiride on the Rate of Progression of Coronary Atherosclerotic Disease…
Cardiology Carere Grant St Lukes-Roosevelt Institute For Health Sciences
6,595
Open Artery Trial (OAT II)
Cardiology Carere Agreement Medical Research Council of Canada 9,450
Clinical outcomes utilizing revascularization and aggressive drug evaluation (COURAGE) Trial
Cardiology Chan Clinical Trial Sanofi-Aventis 48,296
Randomized, Multinational, Multicenter, Double-blind, Placebo-controlled, Two-arm Parallel Group Trial of Rimonabant 20 mg OD For Reducing the Risk of Major Cardiovascular Events in Abdominally Obese Patients With Clustering Risk Factors
Cardiology Fung Clinical Trial The Medicines Co. 17,039
TMC-BIV-02-08 Acuity: Randomized Comparison of Angiomax (bivalirudin) vs Lovenox/Clexane (enoxaparin) in Patients Undergoing Early Invasive Management for Acute Coronary Syndrome Without ST-segment Elevation
Cardiology Fung Agreement Sanofi Recherche 31,900
EFC 5965: Randomized, Multinational, Double-Blind Study, comparing a High Loading Dose Regimen of Clopidogrel versus Standard Dose in Patients with Unstable Angina or Non-ST Segment Elevation Myocardial Infarction Managed with an Early Int
Cardiology Fung Clinical Trial CV Therapeutics Inc. 10,056
CVT 5131: Phase III Randomized Double-Blind Study of Intravenous CVT-3146 vs Adensocan in Patients Undergoing Stress Myocardial Perfusion Imaging
Cardiology Fung Grant VCHA 621,594
Interventional cardiology research - clinical research coordinators positions
Cardiology Fung Clinical Trial National Institutes of Health 101,330
IICT: Atherothrombbosis Intervention in Metabolic Syndrome with Low HDL High Triglycerides & Impact on Global Health Issues (AIM-HIGH)
Cardiology Gin Clinical Trial Sanofi-Aventis Canada Inc. 2,850
Protocol EFC4912 (ACTIVE): Atrial Fibrillation Clopidogrel Trial with Irbesartan for Prevention of Vascular Events
Cardiology Gin Clinical Trial Atherogenics Inc. 25,086
AGI-1067-042 ARISE: Multicenter, Double-blind, Randomized, Placebo-controlled Trial to Study the Reduction of Vascular Inflammation & Coronary Atherosclerosis with AGI-1067, a V-Protectant Reduces Cardiovascular Events in Patients with Coronary...
Cardiology Gin Agreement Atherogenics Inc. 36,896
Follow up of Clinical Outcomes: The Long-Term AGI-1067 plus Usual Care Study- FOCUS
UBC Department of Medicine Page 6 Annual Report 2007
Cardiology Gin Agreement Sanofi-Aventis 106,077
EFC-5826: Randomized, Multinational, Multicenter, Double-blind, Placebo-controlled, Two-arm, Parallel-group Trial of Rimonabant 20mg OD for Reducing the Risk of Major Cardiovascular Events in Abdominally Obese Patients with Clustering Riso…
Cardiology Hamburger Agreement Angiometrx Inc. 13,500
"GAAME"- Gemini Angioplasty & Arterial Measurement Evaluation - An evaluation of the Metricath Gemini System, a percutaneous interventional device intended to make arterial lumen measurements and perform percutaneous transluminal angioplasty…
Cardiology Humphries Grant MSFHR Career Investigator Program 20,000
Secondary prevention - the gap between evidence and practice
Cardiology Humphries Grant CIHR New Investigator MSH-80517 58,500
Angina with "normal" coronary arteries: sex differences in presentation and outcome
Cardiology Humphries Grant CIHR Operating Grant 143,705
Angina with "normal" coronary arteries: sex differences in presentation and outcome
Cardiology Ignaszewski Clinical Trial Novartis Pharmaceuticals Canada Inc.
247
A three-month, multicenter, open-label, single arm, pilot study of the renal safety of everolimus in addition to Neoral in cardiac transplant recipients
Cardiology Ignaszewski Clinical Trial Pfizer Inc. 35,827
A Phase III, multi-center, double-blind, randomized, parallel group evaluation of the fixed combination torcetrapib/atorvastatin, administered orally, once daily(QD) compared with atorvastatin alone on the occurrence of major cardiovascular events in…
Cardiology Jue Contract Various Sources 9,803
Echo Research Account
Cardiology Jue Grant Canadian Institutes of Health Research
2,040
Protocol DC-452-003: ASTRONOMER - The Effect of Cholesterol Lowering on Progression of Aortic Stenosis in Patients with Mild to Moderate Aortic Stenosis
Cardiology Jue Clinical Trial Guidant Corp. 7,300
CAFI: Canadian Atrial Fibrillation Evaluation Study
Cardiology Kerr Grant Canadian Institutes of Health Research
104,861
Resynchronization/Defibrillation for Advanced Heart Failure
Cardiology Kerr Clinical Trial Guidant Corporation 1,500
Canadian Registry of ICD Implant Testing Procedures
Cardiology Kerr Grant Sanofi-Aventis Canada Inc. 82,000
Data Analysis: CARAF II and CAFAF II Databasics
Cardiology Mancini Grant Various Sources 32,300
Quantitative Vascular Studies
Cardiology Mancini Contract Cordis Corp. 72,827
SA: Approaches to Chronic Occlusions with Sirolimus Stents-Cypher (ACROSS-CYPHER)
UBC Department of Medicine Page 7 Annual Report 2007
Cardiology Moss Clinical Trial Novartis Pharmaceuticals Canada Inc.
10,000
A 24-month, mulicentre, randomized, open-label, non-inferiority study of efficacy and safety comparing two exposures of concentration-controlled Certican with reduced Neoral 3.0 gMMF with standard dose Neoral in de Novo Heart transplant
Cardiology Ramanathan Agreement AstraZeneca Canada Inc. 18,525
PLATO (D5130C05262): A Randomized, Double-blind, Parallel-group, Phase III Efficacy and Safety Study of AZD6140 Compared with Clopidogrel for Prevention of Vascular Events in Patients with Non-ST or ST Elevation Acute Coronary Syndrome (ACS)
Cardiology Ramanathan Grant Sanofi-Aventis Canada Inc. 3,000
Protocol GRACE 2: The Global Registry of Acute Coronary Events Expanded Enrollment Program
Cardiology Ricci Clinical Trial National Institutes of Health 62,718
IICT: FREEDOM: Future Revascularization Evaluation in Patients with Diabetes Mellitus: Optimal Management of Multivessel Disease
Cardiology Ricci Clinical Trial Eli Lilly Canada Inc. 40,707
H7T-MC-TAAL (TIMI 38): A Comparison of CS-747 and Clopidogrel in Acute Coronary Syndrome Subjects Who Are to Undergo Percutaneous Coronary Intervention / TIMI 38
Cardiology Saw Agreement The Medicines Co. 3,000
TMC-CAN-0502: A Clinical Trial Comparing Cangrelor to Cloipidogrel in Subjects who Require Percutaneous Coronary Intervention
Cardiology Saw Agreement The Medicines Co. 17,000
TMC-CAN-05-03: A Clinical Trial Comparing Treatment with Cangrelor (in combination with usual care) in Subjects who Require Percutaneous Coronary Intervention CHAMPION PLATFORM
Cardiology Tung Clinical Trial Medtronic USA 2,145
SAVE PACe - Search AV Extension for Promoting Atrioventricular Conduction
Cardiology Webb Clinical Trial Boston Scientific Corp. 500
SYMBIOT III: A prospective randomized trial evaluating the Symbiot III covered stent system in saphenous vein grafts
Cardiology Webb Clinical Trial Angiometrx Inc. 8,100
Protocol GAAME: Gemini Angioplasty and Arterial Measurement Evaluation
Cardiology Webb Clinical Trial Hoffmann-La Roche Ltd. (Canada) 4,318
WEST: Which Early ST Elevation Myocardial Infarction Therapy?
Cardiology Webb Clinical Trial Edwards Lifesciences LLC 16,258
REVIVE Trial - Registry of EndoVascular Implantation of Valves in Europe
Cardiology Webb Clinical Trial TherOx Inc. 11,126
AMI HOT II - A Prospective, Multicentered, Randomized Study of Aqueous Oxygen Therapy for 90 Minutes in Anterior Acute Myocardial Infarction Patients with Successful PCI/Stenting Presenting Within </= Six Hours From Time of Symptom Onset
UBC Department of Medicine Page 8 Annual Report 2007
Cardiology Webb Clinical Trial Edwards Lifesciences LLC 12,660
Milano II Feasibility Study
Cardiology Webb Clinical Trial Edwards Lifesciences LLC 22,598
TVI Registry: Transcatheter Valve Implantation Vancouver Experience
Cardiology Webb Clinical Trial Edwards Lifesciences LLC 33,181
Evolution: Edwards LifeScience Percutaneous Mitral Annulopasty Repair System: A Phase I Feasibility, Non-randomized, Multicenter, Prospective, Consecutive Registry -- A Percutaneous Interventional Treatment of Mitral Regurgitation
Cardiology Webb Clinical Trial Sanofi-Synthelabo 5,000
SHINE TRIAL: A randomized dose ranging study of Hexadecasaccharide including active control, in patients with unstable angina or non-ST-segment elevation myocardial infarction scheduled to undergo percutaneous coronary intervention
Cardiology Webb Clinical Trial Boston Scientific Corp. 238
TAXUS II: A double-blind, controlled, study of the safety and performance of the NIRx(TM) Paclitaxel-coated conformer coronary stent
Cardiology Wong Agreement Schering-Plough Research Institute 15,177
IMPROVE-IT
Cardiology Wong Grant Vancouver Coastal Health Authority 50,000
A Four-year Evaluation of Door-to-Balloon Time and Factors associated with Door-to-Balloon time Prolongation for Primary Percutaneous Coronary Intervention
Cardiology Wong Agreement AstraZeneca Canada Inc. 89,415
D356OL00052 Comparison of the Effects noted in the ApoB/Apo-A-I ratio Using Rosuvastatin and Atorvastatin in patients with acUte coronary Syndrome - CENTAURUS
Cardiology Wong Agreement Sanofi-Aventis Canada Inc. 8,268
IICT: Global registry of Acute Coronary Events Expanded Enrollment Program, Centre for Outcomes Research, University of Massachusetts Medical School (GRACE2)
Critical Care Chittock Grant CIHR Randomized Controlled Trials
MCT-80244 in collaboration with the Institute of Nutrition, Metabolism and Diabetes
1,162,943
(SUGAR) Survival Using Glucose Algorithm Regulation
Critical Care Chittock Agreement Takeda Global Research and Development
5,476
TAK-242-011 A Multicenter, Multinational, Randomized, Double-blind, Placebo-controlled Study to Evaluate the Efficacy and Safety of TAK 242 in Adults with Severe Sepsis
Critical Care Chittock Clinical Trial CIHR Randomized Controlled Trials in collaboration with McMaster University
21,128
IICT: Prophylaxis for Thromboembolism in Critical Care Trial (PROTECT Study)
Critical Care Chittock Agreement Eisai Inc. 25,759
ACCESS: A Controlled Comparison of Eritoran Tetrasodium and Placebo in Patients with Severe Sepsis
UBC Department of Medicine Page 9 Annual Report 2007
Critical Care Chittock Clinical Trial Novartis Pharmaceuticals Canada Inc.
11,883
Protocol TFP008: Phase III Multicenter, Randomized, Placebo-controlled Double-blind, Three-arm Study to Evaluate the Safety & Efficacy of Tifacogin (recombinant tissue factor pathway inhibitor) Administration in Subjects with Severe Community...
Critical Care Chittock Clinical Trial Fresenius Kabi Deutschland GmbH in collaboration with CIHR and Kingston General Hospital Clinical Evaluation Research
1,500
IICT - A randomized trial of glutamine and antioxidant supplementation in critically ill patients: The REDOXS Study
Critical Care Chittock Agreement Various Sources 159,619
Various Clinical Trials Agreements
Critical Care Dodek Grant CIHR Strategic/ RFA Knowledge Translation-Research Syntheses KRS-82618
52,663
Scoping and systematic review of non-invasive mechanical ventilation: Laying the groundwork for development of clinical practice guidelines
Critical Care Dodek Agreement CIHR Team Grant PET-69818 in collaboration with Dalhousie University, Queen's University and Royal Alexandra Hospital
37,976
Understanding and improving communication and decision-making at the end of life
Critical Care Dodek Grant MSFHR HSPR Operating Grants Program - LOI
74,860
HSPRSN Investigative Teams development grant - Intensive Care Unit Patient Safety Team
Critical Care Dodek Grant CIHR Operating Grant 5,500
Active observational study of the adoption and transfer of clinical practice guidelines through education, for ventilator associated pneumonia - ABATE VAP Study
Critical Care Dodek Grant CIHR: Partnership for Health System Improvement PHE-78693
64,726
Relationship between organizational culture and family satisfaction in critical care
Critical Care Dorscheid Grant British Columbia Lung Association 22,500
EGF-receptor glycosylation and airway epithelial repair in asthma…
Critical Care Dorscheid Grant CIHR Doctoral Research Award Fellowship (Fellow: Patchell, Benjamin)
4,583
The role and characterization of Annexin II in airway epithelial wound repair in normal and asthmatic epithelium
Critical Care Dorscheid Grant CIHR Fellowship (Fellow: MacRedmond, Ruth)
5,000
Research Allowance: Acute Lung Injury: FasL, Apoptosis and Protection by Erythropoietin
Critical Care Dorscheid Grant MSFHR Fellowship (Fellow: MacRedmond, Ruth)
50,000
Salary: Acute Lung Injury: FasL, Apoptosis and Protection by Erythropoietin
Critical Care Dorscheid Grant CIHR Operating Grant 100,000
Conjugated Linoleic Acid and Airway Health in Asthma
Critical Care Dorscheid Grant British Columbia Lung Association 21,000
Airway Inflammation and CLA to Reduce Airway Remodeling
Critical Care Dorscheid Grant CIHR Postdoctoral Trainee Fellowship (Fellow: MacRedmond, Ruth)
7,000
Acute lung injury: FasL, Apoptosis and protection by Erythropietin
UBC Department of Medicine Page 10 Annual Report 2007
Critical Care Dorscheid Grant MSFHR Scholar Award 45,000
Airway epithelial injury as a result of corticosteroid-induced apoptosis
Critical Care Dorscheid Grant Canadian Institutes of Health Research (CIHR)
58,500
Glycomics of airway epithelial repair
Critical Care Russell Grant CIHR Doctoral Research Award Fellowship (Fellow: Sutherland, Ainsley)
1,000
Genetic determinants of the host response to infection in critically ill adults with systemic inflammatory response syndrome
Critical Care Russell Clinical Trial Chiron Corp. 65,600
A phase III, multicentre, randomized, placebo-controlled, double-blind, three-arm study to evaluate the safety and efficacy of Tifacogin (recombinant tissue factor pathway inhibitor) administration in subjects with severe community-acquired pneumonia…
Critical Care Russell Contract Medical Research Council of Canada 4,850
A randomized trial of a lung open ventilation strategy in acute lung injury
Critical Care Walley Grant CIHR Operating Grant 122,899
Toll-like receptor signaling in cardiac inflammatory states
Critical Care Walley Grant MSFHR: Distinguished Scholar Award CI-DSH-73(02-1)
120,000
Translating mechanistic understanding of the systemic inflammatory response syndrome (SIRS) to clinical practice via genomics
Critical Care Walley Grant CIHR Operating Grant 40,476
Influence of polymorphisms in coagulation pathway in inflammatory mediator genes on phenotype post-cardiopulmonary bypass surgery
Critical Care Walley Grant MSFHR Postdoctoral Trainee Fellowship ST-PEF-154(06-1) CLIN (Fellow: Boyd, John)
39,000
The heart as an immunologic organ: cardiac myocytes in innate immunity
Critical Care Walley Contract Sirius Genomics Inc. 484,026
CRA: Association of the influence of inflammatory mediator polymorphisms with outcomes in systemic inflammatory response syndrome (SIRS) and multiple organ system failure (MOSF); and SNP Discovery using a whole Genome scan linkage analysis
Endocrinology Elliott Agreement Hoffmann-La Roche Ltd. (Canada)
874 BM18249 - A Multicenter, Double-blind, Randomized, Placebo-controlled Dose Ranging, Phase II Study to Investigate Efficacy Safety, Tolerability and Pharmacokinetics of RO4389620 in patients with Type-2 Diabetes Mellitus Treated with a Stabfn
Endocrinology Elliott Clinical Trial Amgen Inc. 21,429
TREAT - 20010184: Trial to Reduce Cardiovascular Events with Aranesp (darbepoetin alfa) Therapy
Endocrinology Elliott Agreement Hoffmann-La Roche Ltd. (Canada) 15,106
Protocol: NC19794 - A multicenter, open label, extension study to evaluate the long-term safety and tolerability of RO4389620 in Type-2 Diabetic patients from studies BM18248 and BM18249
UBC Department of Medicine Page 11 Annual Report 2007
Endocrinology Elliott Clinical Trial Novartis Pharmaceuticals Canada Inc.
16,969
CDJN608B2302: Navigator Randomized, Double-blind, Placebo-controlled, Forced-titration 2x2 Factorial Design Study of the Efficacy & Safety of Long-term Administration of Nateglinide & Valsartan in the Prevention of Diabetes & Cardiovascular Disease
Endocrinology Elliott Clinical Trial National Institutes of Health 400,901
IICT ACCORD Eye Study: A Substudy of the Action to Control Cardiovascular Disease in Diabetes Study
Endocrinology Kreisman Agreement National Institutes of Health 321
Diabetes Therapy to Improve BMI and Pulmonary Function in CF Subjects with Abnormal Glucose Tolerance
Endocrinology Prior Grant Donations for Health Science Research
212,714
(CEMCOR) Centre for Menstrual Cycle and Ovulation Research
Endocrinology Prior Grant CIHR/ Rx&D Research Program 166,610
(CAMOS) Canadian Multicentre Osteoporosis Study: A cross-sectional and prospective observational study of bone density, bone strength and fracture risk
Endocrinology Sirrs Clinical Trial University Health Network in collaboration with the BC Ministry of Health
123,438
Enzyme Replacement Therapy for Fabry Disease: A Model for the Integration of Rare Disease Therapeutics into the Canadian Health Care System
Endocrinology Thompson Clinical Trial Novo-Nordisk 8,425
A randomised, parallel-group, open-label, multinational trial comparing the efficacy and safety of insulin determir (Levemir R) vs. human insulin (Insulin NPH) used in combination with insulin… with type-1 diabetes
Endocrinology Thompson Grant Canadian Institutes of Health Research (CIHR)
10,000
To reduce IDDM in Type-1 diabetes in the genetically at risk TRIGR
Gastroenterology Anderson Clinical Trial Bristol-Myers Squibb Co. (Canada)
2,067 Protocol AI463049: Long-term Assessment of Treatment Outcomes with Entecavir & Lamivudine for Chronic Hepatitis B Infection in Patients Who Have Enrolled in Phase III Entecavir Trials
Gastroenterology Anderson Clinical Trial Schering Canada Inc. 3,335
Protocol P02569: PEG-Intron as Maintenance Therapy vs an Untreated Control Group in Adult Subjects with Compensated Cirrhosis (METAVIR F4) Secondary to Chronic Hep C who have Failed to Respond to Therapy with Any alpha Interferon + Ribaviri
Gastroenterology Anderson Clinical Trial Schering Canada Inc. 2,091
Protocol P02570: PEG-Intron as Maintenance Therapy vs an Untreated Control Group for Prevention of Fibrosis in Adult Subjects with Chronic Hep C with Hepatic Fibrosis (METAVIR fibrosis score of F2/F3) Who Have Failed Therapy with PEG-Intron
Gastroenterology Anderson Clinical Trial Centocor Inc. 2,242
Protocol C0168T37 (ACT 1): Randomized Placebo-Controlled Double-Blind Trial to Evaluate the Safety and Efficacy of Infliximab in Patients with Active Ulcerative Colitis
UBC Department of Medicine Page 12 Annual Report 2007
Gastroenterology Anderson Clinical Trial Bristol-Myers Squibb Pharmaceutical Group (Canada)
13,385
Protocol AI463-901: A Preliminary Assessment of Safety and Antiviral Activity of Open-Label Entecavir Plus Lamivudine Therapy in Subjects with Chronic Hepatitis B Who Have Viremia on Monotherapy in Other Entecavir Trials
Gastroenterology Anderson Clinical Trial Tillotts Pharma AG 4,343
Protocol TP0308: - EPIC-2 Phase III Randomized Placebo-Controlled Double-Blind Parallel Group Multicentre Study to Assess the Efficacy & Safety of Omega-3 Free fatty Acids (Epanova) for the Maintenance of Symptomatic Remission in Subjects…
Gastroenterology Enns Clinical Trial Otsuka America Pharmaceutical Inc. 25,538
A Prospective, Open-Label Study to Evaluate the Adacolumn Apheresis System for the Treatment of Moderate to Severe Crohn's Disease (512-04-208)
Gastroenterology Enns Clinical Trial Otsuka America Pharmaceutical Inc. 42,418
A Prospective, Randomized, Double-blinded, Placebo (Sham)-controlled Study to Evaluate the Safety and Effectiveness of the Adacolumn Apheresis System for the Treatment of Moderate to Severe Crohn's Disease (512-04-206)
Gastroenterology Enns Clinical Trial Otsuka America Pharmaceutical Inc. 34,888
512-04-207: A Prospective, open-label study to evaluate the Adacolumn Aspheresis System for the treatment of moderate to severe Ulcerative Colitis
Gastroenterology Enns Clinical Trial Abbott Laboratories 80,454
A Multicenter, Open-label Study of the Human Anti-TNF Monoclonal Adalimumab in Subjects with Crohn's Disease (M04-690)
Gastroenterology Enns Grant University of Alberta 5,512
A randomized, placebo-controlled, double-blind, multicenter, study to determine the efficacy and safety of VSL #3 probiotic food supplement mixture in prevention of endoscopic recurrence of Crohn's disease after ileo-colonic surgical resect
Gastroenterology Enns Clinical Trial Tillotts Pharma AG 2,625
A phase III randomized, placebo-controlled, double-blind, parallel group, multi-centre study to assess the efficacy and safety of Omega-3 free fatty acids (Epanova(TM)) for the maintenance of symptomatic remission in subjects with Crohn's Disease
Gastroenterology Enns Clinical Trial Abbott Laboratories 9,115
M02-433 A multi-center, randomised, double-blind, placebo-controlled study of the Human Anti-TNF Monoclonal Antibody Adalimumab for the Maintenance of clinical remission in subjects with Crohn's disease. Clinical Study Protocol M02-433
Gastroenterology Erb Agreement Hoffmann-La Roche Ltd. (Canada) 5,200
IMPROVE -ML21035 - Individualized Management with Pegasys RBV Offering Viral Eradication
Gastroenterology Kwan Agreement Gilead Sciences 8,434
GS-US-174-0108: A Phase II, Double-Blind, Multi-Center, Randomized Study Comparing Tenofovir Disoproxil Fumarate, Emtricitabine Plus Tenofovir Disoproxil
UBC Department of Medicine Page 13 Annual Report 2007
Fumarate, and Entecavir in the Treatment of chronic Hepatitis B Subjects with Decomped
Gastroenterology Kwan Clinical Trial Idenix Pharmaceuticals Inc. 19,168
NV-02B-022: An Open Label Trial of Telbivudine (LdT) in Adults with Chronic Hepatitis B Previously Treated in Idenix-Sponsored Telbivudine Studies
Gastroenterology Salh Grant Vancouver Coastal Health Research Institute (VCHRI)
60,000
Established Clinician: The role of integrin linked kinase in inflammatory bowel disease
Gastroenterology Salh Grant Geraldine Dow Ferry Endowment Fund
20,000
The role of integrin linked kinase in inflammatory bowel disease
Gastroenterology Steinbrecher Grant Heart and Stroke Foundation of British Columbia and Yukon
70,482
Activation of macrophage growth and survival pathways by oxidized LDL
Gastroenterology Tai Grant CIHR Doctoral Research Award JDD-83918 (Fellow: Tang, Michelle)
1,000
The role of SPARC in the activation of the extrinsic pathway in apoptosis for therapy-refractory tumors
Gastroenterology Tai Grant Cancer Research Society 150,000
Understanding the contribution of chemotherapy resistant cancer cells and the tumor microenvironment in gastrointestinal tumor metastasis
Gastroenterology Tai Grant Michael Smith Foundation for Health Research
80,000
Role of SPARC in cancer therapy
Gastroenterology Tai Grant Ferring Pharmaceuticals 500
Gastrointestinal Cancer Research
Gastroenterology Tai Grant Canadian Institutes of Health Research (CIHR)
85,592
The role of SPARC in Cancer Therapy Sensitization
Gastroenterology Tai Grant CIHR New Emerging Team Program CST-85477
282,498
Genomic, imaging and modeling approaches to advance population-based colorectal cancer screening
Gastroenterology Yoshida Clinical Trial Idenix Pharmaceuticals Inc. 4,445
NV-02B-011: A Randomized, Double-blind Trial of Telbivudine (LdT) vs Lamivudine in Adults with Decompensated Chronic Hepatitis B and Evidence of Cirrhosis
Gastroenterology Yoshida Agreement Hoffmann-La Roche Ltd. (Canada) 14,737
ML17908: A Phase IV Randomised, Multicentre, Efficacy and Safety Study Examining the Effect of Induction Dosing with the Combination of Peginterferon, alfa-2a and Ribavirin with Chronic Hepatitis C Infected with Hepatitis C Genotype I
Gastroenterology Yoshida Clinical Trial Human Genome Sciences Inc. 20,669
ALFR-HC-06: A Randomized, Multicentre, Open-label Study to Evaluate the Efficacy and Safety of Albuferon in Combination with Ribavirin in Interferon Alfa Naive Subjects with Chronic Hepatitis C Genotype 2 or 3
Gastroenterology Yoshida Agreement Migenix Inc. 36,253
HCV-05-004: A Phase II Multicentre Extension Study to Evaluate the Safety and Efficacy of Celgosivir in Combination with Peginterferon alfa-2b, with or without Ribavirin, for an Additional 36 Weeks
UBC Department of Medicine Page 14 Annual Report 2007
Gastroenterology Yoshida Grant Geraldine Dow Ferry Endowment Fund
55,000
Endowment for inflammatory bowel disease research and education
Gastroenterology Yoshida Clinical Trial Human Genome Sciences Inc. 82,355
ALFR-HC-04: A Phase II-b Randomized, Multicenter, Active-controlled, Open-Label Study to Evaluate the Efficacy & Safety of Albuferon (recombinant human albumin-interferon alfa fusion protein) in Combination with Ribavirin in Interferon Alfa ......
Gastroenterology Yoshida Agreement Human Genome Sciences Inc. 86,889
ACHIEVE 1: A Phase III Randomized, Multicentre Study to Evaluate the Efficacy and Safety of Albumin Interferon Alfa-2b (alb-IFN) in Combination with Ribavirin Compared with Peginterferon Alfa-2a (pegasys or PEG-IFNa2a) in Combination with R
Gastroenterology Yoshida Clinical Trial Schering Canada Inc. 13,665
P03685: A Study to Assess Treatment with PEG-Intron and Rebetol in Naive Patients with Genotype 1 Chronic Hepatitis C and Slow Virological Response
Gastroenterology Yoshida Agreement Vertex Pharmaceuticals Inc. 32,387
VX06-950-106: A Phase II Study of Telaprevir (VX-950) in combination with Peginterferon Alfa-2a (Pegasys) and Ribavirin (Copegus) in subjects with Genotype 1 Hepatitis C who have not Achieved Sustained Viral Response with a Prior course of…
Gastroenterology Yoshida Agreement Human Genome Sciences Inc. 151,332
ACHIEVECA102: A Phase III Randomized, Multicenter Study to Evaluate the Efficacy and Safety of Albumin Interferon Alfa-2b (alb-IFN) in combination with Ribavirin compared with Peginterferon Alfa2a (PEG_INF a2a) in combination with Ribavirin
Gastroenterology Yoshida Clinical Trial Ortho Biotech 50
HEPC-AN-2: A Prospective Study to Evaluate the Hemoglobin Levels of Hepatitis C Virus Infected Patients Receiving Treatment with Combination Ribavirin/Interferon or Ribavirin/Pegylated Interferon
Gastroenterology Yoshida Agreement Hoffmann-La Roche Ltd. (Canada) 5,450
APPROACH: ML20090 - A Prospective Study of Peginterferon alfa-2a and Ribavirin: Outcomes Assessment in Chronic Hepatitis C Patients
General Internal Medicine
Khan Grant CIHR Operating Grant MOP-79329 39,000
Gender and ethnic differences in hypertension and Diabetes Mellitus
General Internal Medicine
Khan Grant CIHR New Investigator IGN-80502 58,500
Gender and ethnic differences in hypertension and Diabetes Mellitus
General Internal Medicine
Ma Grant UBC Faculty of Medicine 4,600
Faculty development initiative grants: Use of clinical simulators in teaching lumbar punctures in an internal medicine curriculum
General Internal Medicine
Magee Grant CIHR: Institute of Human Development and Child/Youth Health
93,878
Birth under 29 weeks: improving outcomes for mothers and babies
UBC Department of Medicine Page 15 Annual Report 2007
General Internal Medicine
Magee Grant MSFHR Scholar Award CI-SCH-57(02-1)
80,000
CHIPS -- Control of Hypertension In Pregnancy Study: A pilot trial
General Internal Medicine
Magee Grant CIHR: IWRHTP Graduate Fellowship (Fellow: Massey, Kiran)
17,850
The Canadian Perinatal Network
General Internal Medicine
Magee Grant CFRI: IWRHTP Graduate Fellowship (Fellow: Massey, Kiran)
3,000
The Canadian Perinatal Network
General Internal Medicine
Ong-Lam Clinical Trial Montreal Heart Institute 3,715
IICT: Stop Pain Project - Study l: Assessment of Chronic Pain Burden and Management in Canada
General Internal Medicine
Palepu Grant CIHR: Interdisciplinary Capacity Enhancement (ICE) Teams Grant Program
8,600
Interdisciplinary capacity enhancement grant in homelessness, housing and health
General Internal Medicine
Palepu Grant MSFHR Scholar Award 100,000
Health research of vulnerable urban populations
Geriatric Medicine Adler Grant UBC VPR Research Development
Fund
10,000 Belief of combatants in Darfur - an exploration
Geriatric Medicine Beattie Agreement CIHR Operating Grant 6,020
Canadian Alzheimer's disease quality of life study
Geriatric Medicine Beattie Agreement CIHR Operating Grant 8,580
Canadian Alzheimer's disease quality of life study
Geriatric Medicine Cook Grant St. Paul's Hospital 50,000
Physician Scholars Program Salary Award
Geriatric Medicine Madden Grant CIHR Operating Grant 60,522
Exercise and cardiovascular control during upright tilt in older adults with Type-2 Diabetes
Geriatric Medicine McElhaney Clinical Trial CV Technologies Inc. 41,221
IICT: Efficiency and Safety of Cold-fX in the Prevention of Upper Respiratory Tract Infections in Community-dwelling Adults: A Multicentre, Randomized, Double-blind, Placebo-controlled Trial
Geriatric Medicine McElhaney Clinical Trial GlaxoSmithKline (Canada) Inc. 214,033
IICT Main: T-Cell Responses to Influenza Vaccination in Older Adults
Geriatric Medicine McElhaney Clinical Trial Merck Frosst Canada Ltd. 566
M.A.S.T.E.R. - Measuring Herpes Zoster and Post-Herpetic Neuralgia Assoc Burden of Illness and Health Care Utilization and Costs in Canada
Geriatric Medicine McElhaney Grant CIHR: International Opportunities Program - Development/ Planning Grant
24,990
The Roadmap to Improved Correlates of Protection Against Influenza
Geriatric Medicine Meneilly Clinical Trial Merck Frosst Canada Ltd. 28,000
IICT - Sitagliptin in the Elderly: Single Dose Study
Geriatric Medicine Meneilly Grant Various Sources 7,535
Diabetes in the Elderly
UBC Department of Medicine Page 16 Annual Report 2007
Geriatric Medicine Wong Grant Royal College of Physicians and Surgeons of Canada
16,000
Impact of a Novel, CanMEDS Focused Quality Improvement Curriculum on Knowledge Translation of Quality Improvement Skills Among Internal Medicine Residents
Hematology Broady Grant VGH and UBC Hospital Foundation -
Mentored Clinician Scientist Comp
50,000 Salary: Generation of antigen specific T regulatory cells for prevention of GVHD through induction of transplantation tolerance
Hematology Broady Grant British Columbia Transplant Society (BCTF-OPG-05-2005)
20,000
Extracorporeal Photopheresis: A Novel Approach to induce Transplant Tolerance?
Hematology Broady Grant Vancouver Coastal Health Authority 20,000
Matching Funds - Extracorporeal Photopheresis: A Novel Approach to Induce Transplant Tolerance
Hematology Broady Grant Vancouver Coastal Health Research Institute
10,000
VCHRI Global Collaboration Fund
Hematology Forrest Agreement Novartis Pharmaceuticals Canada Inc.
13,130
CAMN107A2303: A Phase III Multicentre, Open-label, Randomized Study of Imatinib versus Nilotinib in Adult Patients with Newly Diagnosed Philadelphia Chromosome Positive (PH+) chronic Myelogenous Leukemia in Chronic Phase (CML-CP)
Hematology Forrest Agreement Novartis Pharmaceuticals Canada Inc.
26,957
CAMN107A2101: A Phase 1A/II Multicenter, Dose-escalation Study of Oral AMN107 on a Continuous Daily Dosing Schedule in Adult Patients with Gleevec (imatinib)-resistant/interolerant CML in Chronic or Accelerated Phase or Blast Crisis+
Hematology Forrest Agreement Novartis Pharmaceuticals Canada Inc.
13,495
CLBH589B2211: A Phase II, Multicentre Study of Oral LBH589 in Patients with Accelerated Phase or Blast Phase (Blast Crisis) Chronic Myeloid Leukemia with Resistant Disease Following Treatment with at Least Two BCR-ABL Tyrosine Kinase Inhis
Hematology Forrest Agreement Bristol-Myers Squibb Co. (Canada) 650
CA180034 - A Randomized, Two-by-Two, Multicenter, Open-label Phase III Study of BMS-354825 Administered Orally at a Dose of 50 mg or 70mg Twice Daily or 100mg or 140 mg Once Daily in subjects with Chronic Phase Philadelphia Chromosome or BCR
Hematology Forrest Agreement Novartis Pharmaceuticals Canada Inc.
12,935
CLBH589B2202: A Phase II, Multicentre Study of Oral LBH589 in Patients with Chronic Phase Chronic Myeloid Leukemia with Resistant Disease Following treatment with at Least Two BCR-ABL Tyrosine Kinase Inhibitors
Hematology Forrest Clinical Trial Bristol-Myers Squibb Co. (Canada) 39,987
CA180017: Randomized Multicenter Open-Label Study of BMS-354825 vs Imatinib Mesylate (Gleevec) 800 mg/d in Subjects with Chronic Phase Philadelphia Chromosome-Positive Chronic Myeloid Leukemia who have disease that is resistant to Imatinib
UBC Department of Medicine Page 17 Annual Report 2007
Hematology Forrest Agreement Bristol-Myers Squibb Co. (Canada) 39,058
CA180035: A Randomized, Two-arm, Multicenter, Open-label Phase II Study of BMS354825 Administered Orally at a Dose of 70 mg Twice Daily or 140 mg Once Daily in Subjects with Chronic Myeloid Leukemia in Accelerated Phase or in Myeloid
Hematology Forrest Agreement Novartis Pharmaceuticals Canada Inc.
25,121
CAMN107A2109: An Open-label, Multicentre, Expanded Access Study of Oral AMN107 in Adult Patients with Imatinib (Glivic/Gleevec - resistant) or - Intolerant Chronic Myeloid Leukemia in Blast Crisis Accelerated Phase or Chronic Phase…
Hematology Forrest Agreement Bristol-Myers Squibb Co. (Canada) 4,250
CA180033-038: A Study of Dasatinib (BMS-354825) in Subjects with Chronic Myelogenous Leukemia with Accelerated or Myeloid or Lymphoid Blast Phase or Philadelphia Chromosome Positive Acute Lymphoblastic Leukemia who are Resistant to…
Hematology Forrest Clinical Trial Bristol-Myers Squibb Co. (Canada) 99,002
CA180013: A Phase II Study to Determine the activity of BMS-354825 in Subjects with Chronic Phase Philadelphia Chromosome-Positive Chronic Myeloid Leukemia who have Disease that is Resistant to High Dose Imatinib Mesylate (Gleevec) or who ...
Hematology Hogge Clinical Trial EpiCept Corporation 12,455
A Multicenter, randomized, open-label study to evaluate the safety and efficacy of immunotherapy with subcutaneous maxamine (Histamine dichloride) plus proleukin vs. no treatment (standard of care) in patients with acute myeloid leukemia
Hematology Hogge Agreement Celmed BioSciences Inc. 62,695
CR-ECP-001 Safety, Biological and Clinical Efficacy of Two Intensity Levels of Theralux Extracorporeal Photochemotherapy in Subjects with Extensive Chronic GVHD Refractory or Intolerant to Standard Therapy
Hematology Hogge Agreement Xanthus Life Sciences 72,591
A Phase II Open-label Study of Amonafide L-Malate in Combination with Cytarabine in Subjects with Secondary Acute Myeloid Leukemia (AML)
Hematology Hogge Clinical Trial Vion Pharmaceuticals Inc. 28,475
CLI-037: A Phase III Randomized Study of Cloretazine (VNP40101M) and Cytosine Arabinoside (AraC) in Patients with Acute Myeloid Leukemia in First Relapse
Hematology Hogge Agreement Abbott Laboratories Ltd. (Canada) 19,630
M05-756: A Phase I Study of ABT-869 in Patients with Refractory or Relapsed Acute Myelogenous Leukemia (AML) or Myelodysplastic Syndrome (MDS)
Hematology Hogge Agreement Therakos Inc. 27,727
UVADEX - CD-2: A Randomized, Controlled, Parallel-Group, Multicenter, Study of Extracorporeal Photoimmune Therapy with UVADEX for the Treatment of Patients with Newly Diagnosed Acute Graft-vs-Host Disease
Hematology Humphries Grant CIHR Postdoctoral Fellowship MFE-78150 (Fellow: Yung, Eric)
40,000
Salary: Novel Strategies for Genetic Modification and Expansion of Hematopoietic Stem Cells
UBC Department of Medicine Page 18 Annual Report 2007
Hematology Humphries Grant MSFHR Junior Gradiate Studentship ST-JGS-747(06-1)BM (Fellow: Miller, Michelle)
2,500
Use of recombinant fusion protein to expand hematopoietic stem cells in vitro and to elucidate mechanisms that determine the expansion and self-renewal potential of mouse fetal liver and adult hematopoietic stem cells
Hematology Humphries Grant Stem Cell Network (SCN) - Networks of Centres of Excellence (NCE)
39,500
Cell therapy for muscular disease
Hematology Humphries Grant Stem Cell Network (SCN) - Networks of Centres of Excellence (NCE)
40,000
Cancer stem cell genomics and therapeutics
Hematology Humphries Grant Stem Cell Network (SCN) - Networks of Centres of Excellence (NCE)
10,000
Targeted leukemic stem cell therapeutics
Hematology Humphries Grant MSFHR Postdoctoral Trainee Fellowship ST-PDF-261(04-1)BM (Fellow: Yung, Eric)
7,000
Novel strategies for genetic modification and expansion of hematopoietic stem cells
Hematology Humphries Grant CIHR Postdoctoral Fellowship MFE-78150 (Fellow: Yung, Eric)
5,000
Research Allowance: Novel strategies for genetic modification and expansion of hematopoietic stem cells
Hematology Humphries Grant Stem Cell Network (SCN) - Networks of Centres of Excellence (NCE)
18,976
Development of technologies for the derivation, propagation and differentiation of hESC
Hematology Humphries Grant CIHR Team Grant Program RMF-82499
112,300
Analysis of stem cells using a new high-throughput technology for interrogating the molecular responses of single cells
Hematology Lansdorp Grant Stem Cell Network (SCN) - Networks of Centres of Excellence (NCE)
9,045
Development of technologies for the derivation, propagation, and differentiation of hESC
Hematology Lansdorp Grant Canada Foundation for Innovation Infrastructure Operating Fund 3857
5,156
CFI Infrastructure Operating Funds -- Stem Cell Centre -- Centre Share
Hematology Lansdorp Grant CFI Infrastructure Operating Fund 3857
95,009
CFI Infrastructure Operating Funds -- Stem Cell Centre -- Operations
Hematology Lansdorp Grant CIHR/Strategic: Request for Applications (Full) GMH-79042
490,225
Stem cells for the treatment of bone marrow failure
Hematology Lansdorp Grant CIHR Operating Grant MOP-38075 159,386
Replicative shortening of telomeres in human cells
Hematology Leger Clinical Trial Novartis Pharmaceuticals Corp. 1,352
(CSTI571ACA09) An Open-label, Randomized, Multicentre Study Comparing Gleevec (Imatinib) at Doses of 400mg and 800mg in Obtaining Major Molecular Response in Chronic Phase Patients with Philadelphia Chromosome Positive Chronic Myelogenous Leukemia…
Hematology Leger Clinical Trial Wyeth-Ayerst Research 14,688
An Open-label, Randomized, Phase III Trial of Intravenous Temsirolimus (CC1-779) at Two Dose Levels Compared to Investigator's Choice Therapy in Relapsed, Refractory Subjects with Mantle Cell Lymphoma (MCL)
UBC Department of Medicine Page 19 Annual Report 2007
Hematology Leger Grant Novartis Pharmaceuticals Canada Inc.
2,500
Definition of the Frequency of Organ Toxicity and Death Related to Iron Overload in Red Cell Transfusion-dependent Patients with Myelodysplastic Syndrome (MDS)
Hematology Leitch Grant Novartis Pharmaceuticals Canada Inc.
7,700
Determination of the difference in neutropenia, thrombocytopenia, and leukemia-free survival in patients with myelodysplastic syndrome (MDS) according to receipt of iron chelation therapy (ICT)
Hematology Leitch Grant Novartis Pharmaceuticals Canada Inc.
12,000
Definition of the Frequency of organ toxicity and death related to iron overload in red cell transfusion-dependent patients with idiopathic myelofibrosis (IMF)
Hematology Leitch Clinical Trial Novartis Pharmaceuticals Canada Inc.
3,510
Protocol CAMN107ACA01: A Canadian Open-label, Multicenter, Expanded Access Study of Oral AMN 107 in Adult Patients With Imatinib (Glivec(R))/Gleevec(R)) - Resistant or - Intolerant Chronic Myeloid Leukemia in Blast Crisis, Accelerated phase…
Hematology Leitch Clinical Trial Janssen-Ortho Inc. 8,455
(VELCADE) An Open-label, Randomized Study of VELCADE(R)/Melphalan/Predisone vs. Melphalan/Prednisone in Subjects With Previously Untreated Multiple Myeloma
Hematology Leitch Grant British Columbia Cancer Foundation 2,000
Molecular Diagnosis of Myelodysplastic Syndromes
Hematology Leitch Grant Novartis Pharmaceuticals Canada Inc.
8,200
Determination of the difference in red cell transfusion requirements in patients with myelodysplastic syndrome (MDS) according to receipt of iron chelation therapy (ICT)
Hematology Schrader Grant CIHR - Canada Research Chair Tier I 100,000
Canada Research Chair Tier I in immunology - John Schrader
Hematology Shepherd Clinical Trial Novartis Pharmaceuticals Canada Inc.
1,840
A phase III study of ST1571-106 versus Interferon-a (IFN-A) combined with Cytarabine (Ara-C0) in patients with newly diagnosed previously untreated Philadelphia chromosome positive (Ph+) chronic myelogenous leukemia in chronic phase (CML-CP)
Hematology Smith Grant Canada Research Chair Tier II (CIHR) 950-203507
41,667
Canada Research Chair in cell therapies for Dr Clayton Smith
Hematology Smith Grant Stem Cell Network (SCN) - Networks of Centres of Excellence (NCE)
25,000
Canadian cord blood stem cell initiative
Hematology Smith Grant British Columbia Transplant Society 30,000
Diagnosis of graft vs. host disease using high throughput flow cytometry
Hematology Smith Grant National Institutes of Health Research Grant 1 R01 CA108752-01A2
234,950
Transplantation of G-CSF Stimulated Marrow vs Blood
UBC Department of Medicine Page 20 Annual Report 2007
Hematology Smith Agreement AnorMed Inc. 4,167
A Multicentre, Randomized, Double-blind, Placebo-controlled, Comparative Trial of AMD3100 plus G-CSF vs. C-CSF Plus Placebo to Mobilize and Collect 5x10 CD34+ Cells/kg in Non-Hodgkins Lymphoma Patients for Autologous Transplantation
Hematology Smith Clinical Trial AnorMed Inc. 17,069
AMD3100-C201: Treatment with AMD3100 in Non-Hodgkin's Lymphoma and Multiple Myeloma Patients to Increase the Number of Peripheral Blood Stem Cells When Given a Mobilizing Regimen of G-CSF
Hematology Smith Agreement AnorMed Inc. 2,780
Protocol 3102CA: A Multicenter, Randomized, Double-blind, Placebo-controlled, Comparative Trial of AMD3100 (241ug/kg) plus G-CSF vs. G-CSF Plus Placebo to Mobilize and collect 6/s0 CD34+ Cells/kg in Multiple Myeloma Patients…
Hematology Song Agreement Gentium S.P.A. 1,300
Defibrotide for the Treatment of Severe Hepatic Veno-Occlusive Disease in Hematopoietic Stem Cell Transplant Patients: A Historically-Controlled, Multicentre Phase III Study to Determine Safety & Efficacy
Hematology Song Grant National Cancer Institute of Canada 3,000
A Randomized Phase III Study of Thalidomide and Prednisone as Maintenance Therapy Following Autologous Stem Cell Transplant in Patients with Multiple Myeloma
Hematology Song Agreement Celgene Corp. 55,307
MM016: A Multicentre, Single-arm, Open-label Expanded Access Program for Lenalidomide Plus Dexamethasone in Previously Treated subjects With Multiple Myeloma
Hematology Song Agreement Novartis Pharmaceuticals Canada Inc.
13,520
CLBH589B2203: A Phase II Study of LBH589 in adult patients with Multiple Myeloma who have received at least two prior lines of therapy and whose disease is refractory to the most recent line of therapy
Hematology Sutherland Agreement Centocor Inc. 117,680
Protocol C0328T06: A Phase II Randomized, Double-blind, Placebo-controlled Study Comparing the Combination of CNTO328 (Anti-IL-6 Monoclonal Antibody) and Velcade vs. Velcade Alone in Subjects with Relapsed or Refractory Multiple Myeloma
Hematology Sutherland Agreement Ortho Biotech 14,820
DOXIL-MMY-2001: A Phase II Study to Assess the Safety and Efficacy of DBd combination Therapy (DOXIL/CAELYX) VELCADE and Dexamethasone for Previously Untreated Multiple Myeloma Patients
Hematology Sutherland Clinical Trial Janssen-Ortho Inc. 48,027
DOXIL-MMY-3001: A Randomized, Controlled Study of DOXIL/CAELYX (doxorubicin HCL liposome injection) and Velcade (bortezomib) or Velcade Monotherapy for the Treatment of Relapsed Multiple Myeloma
UBC Department of Medicine Page 21 Annual Report 2007
Hematology Toze Clinical Trial Celmed BioSciences Inc. 10,400
TH9402/II/NHL/002: A Phase II Study of Autologous Transplantation with TH9402 Photodynamic Cell Processing of the Progenitor Cell Graft for Patients with Non-Hodgkin's Lymphoma (Screening Evaluation)
Hematology Vickars Clinical Trial Novartis Pharmaceuticals Canada Inc.
240
ICL670 Exjade: A Study to Provide Expanded Access of EXJADE (deferasirox) to Patients with Congenital Disorders of Red Blood Cells and Chronic Iron Overload From Blood Transfusions Who Cannot Adequately be Treated with Other Locally…
Hematology Vickars Grant Hoffmann-La Roche Ltd. (Canada) 10,000
IICT: Review of Patients at St. Paul's Hospital With Immune Phenomena Treated With Rituximab; Clinical and Laboratory Characteristics and Outcome - Retrospective Chart Review (10306C)
Hematology Vickars Grant Hoffmann-La Roche Ltd. (Canada) 2,730
Protocol McMaster R-ITP: A Randomized, Double-blind, Placebo-controlled Pilot Trial of Rituximab for Non-splenectomized Adults with Acute Immune Thrombocytopenic Purpura Receiving Standard Treatment (R-ITP)
Hematology Vickars Clinical Trial Novartis Pharmaceuticals Canada Inc.
96,570
(EXJADE - CICL670AUS03) An Open-label, Safety and Tolerability Study of Deferasirox for Treatment of Transfusional Iron Overload in Low-risk and INT-1, Myelodysplastic Patients Using Serum Ferritin Monitoring
Hematology Vickars Grant Association of Hemophilia Clinic Directors of Canada
2,000
A survey of factor prophylaxis in patients with Hemophilia followed in Canadian Hemophilia treatment centers
Infectious Diseases Av-Gay Grant MSFHR: Postdoctoral Trainee
Fellowship ST-PDF-111(05-1)BM (Fellow: Bach, Horacio)
23,875
Molecular Analysis of Mycobacterium Tuberculosis Protein Phosphatase
Infectious Diseases Av-Gay Grant CIHR Operating Grant 95,098
Molecular analysis of Mycobaterium tuberculosis protein kinases and phosphatases
Infectious Diseases Av-Gay Contract Nitric Bio Therapeutics Inc. 24,981
Antimicrobial Activity of Gaseous Nitric Oxide
Infectious Diseases Av-Gay Contract Pulmonox Medical Inc. 18,750
SA: The Effect of Nitric Oxide on Viral Infection
Infectious Diseases Av-Gay Grant British Columbia Lung Association 21,000
Mycobacterium tuberculosis protein Kinase J: Role in infectious and antibiotic resistance
Infectious Diseases Av-Gay Contract Enox Biopharma Inc 25,131
SC: Coating and In vitro Examination of Tympanostomy Tubes for Ottis Media
Infectious Diseases Av-Gay Grant Vancouver Coastal Health Authority 10,000
Role of cholesterol in tuberculosis infection
Infectious Diseases Av-Gay Grant VGH Foundation - TB VETS 70,000
Tuberculosis research
UBC Department of Medicine Page 22 Annual Report 2007
Infectious Diseases Brunham Grant CIHR Rx & D Research Program Fellowship (Fellow: Zaharik, Michelle)
20,000
Developing a Chlamydia trachomatis vaccine by optomizing dendritic cell responses
Infectious Diseases Brunham Contract Genome British Columbia 150,000
CRA: Accelerated Chlamydia trachomatis Immunoproteomic Vaccine Enterprise (ACTIVE)
Infectious Diseases Brunham Contract Sanofi Pasteur Ltd. 462,000
CRA: Biological and Immunogenic Evaluation of C. trachomatis Vaccine Candidate Antigens and Formulations
Infectious Diseases Brunham Grant CIHR Rx & D Research Program Fellowship (Fellow: Zaharik, Michelle)
2,500
Developing a Chlamydia trachomatis vaccine by optomizing dendritic cell responses
Infectious Diseases Brunham Agreement National Institutes of Health 65,730
Inflammation and ovarian cancer
Infectious Diseases Brunham Agreement National Institutes of Health 103,425
Comparative genomics of the Chlamydiaceae family of obligate intracellular parasites: a study of new laboratory methods to better understand Chlamydia infection
Infectious Diseases Brunham Grant CIHR Proof of Principle 150,000
Accelerated Chlamydia Trachomatis Immunoproteomic Vaccine Enterprise
Infectious Diseases Burdge Clinical Trial CIHR Randomized Controlled Trials 875
Predictors of Antiretroviral Pharmacokinetics in HIV-Infected Women with Virologic Suppression on Combination Antiretroviral Therapy
Infectious Diseases Cherkasov Contract Genome British Columbia - Full Proposal
96,000
Functional Genomics for Emerging Infectious Diseases
Infectious Diseases Cherkasov Grant CIHR Fellowship MFE-76560 (Fellow: Ban, Fuqiang)
16,822
Salary: Design and discovery of novel antimicrobial peptides as effective therapeutics against drug-resistant bacteria
Infectious Diseases Cherkasov Grant MSFHR: Senior Graduate Studentship Award ST-SGS-362(06-1)BM (Fellow: Hsing, Michael)
2,500
Bioinformatics of sequence indels: novel applications for protein network analysis, drug target identification and drug development
Infectious Diseases Cherkasov Grant CIHR Doctoral Research Award MDR-75875 (Fellow: Fjell, Christopher)
1,000
Quantitative Structure-Activity Relationships and Machine Learning Techniques for Identification of Novel Antimicrobial Agents
Infectious Diseases Chow Grant CIHR: MD/PhD Program Studentship MMP-71794 (Fellow: Heslop, Claire)
1,000
Biomarkers of oxidative stress: An evaluation of nutrient-gene interactions in coronary artery disease
Infectious Diseases Chow Grant CIHR: MD/PhD Program Studentship MMP-65952 in collaboration w/ the Institute of Circulatory & Respiratory Health (Fellow: Heine, Heather)
1,000
Myocardial regeneration with hematopoietic stem cells
Infectious Diseases Chow Grant CIHR: MD/PhD Program Studentship MMP-71793 (Fellow: Berkhout, Susan)
1,000
Life at the margins: An interdisciplinary analysis of the social determinants of HIV/AIDS and women's health
UBC Department of Medicine Page 23 Annual Report 2007
Infectious Diseases Chow Grant CIHR: MD/PhD Program Studentship MDG-79753 (Fellow: Astanehe, Arezoo)
44,000
CIHR MD/PhD Grants for Arezoo Astanehe and Brennan Eadie
Infectious Diseases Chow Grant CIHR: MD/PhD Program Studentship MMP-65951 (Fellow: Joe, Aaron)
1,000
Molecular determinants of stem cell trafficking
Infectious Diseases Chow Grant CIHR: MD/PhD Program Studentship IMD-78843 (Fellow: Young, Fiona)
1,000
The role of ABCA1 in the central nervous system
Infectious Diseases Chow Grant MSFHR Grant-in-Aid OT-GIA-001056 22,000
MD/PHD Program Support
Infectious Diseases Chow Grant CIHR: MD/PhD Program Studentship MMP-58313 (Fellow: Coburn, Bryan)
1,000
The pathogenomics of salmonella infection
Infectious Diseases Chow Grant CIHR: MD/PhD Program Studentship MMP-58293 (Fellow: Brunham, Liam)
1,000
Identification and validation of genes modulating LDL cholesterol in humans
Infectious Diseases Hmama Grant CIHR: HIV/AIDS Research Program MOP-84557
85,737
Role of the Mycobacterial Lipoamide Dehydrogenase in the Pathogenesis of Tuberculosis
Infectious Diseases Hmama Grant British Columbia Lung Association 30,000
Role of the Macrophage Receptor CD14 in Anti-TB Immunity
Infectious Diseases Hmama Grant MSFHR Scholar Award 20,000
Molecular study of interaction between Mycobacterium tuberculosis and the macrophage endosomal compartment: an approach to identify mycobacterial virulence factors
Infectious Diseases Hmama Grant MSFHR Career Investigator Program 60,000
Translational TB research: Novel vaccine and drug target
Infectious Diseases Hmama Grant Vancouver Coastal Health Authority 85,000
Salary support: Dr. Hmama
Infectious Diseases Hmama Grant VGH Foundation - TB VETS 75,000
Tuberculosis research
Infectious Diseases Hmama Grant VCHA 10,000
Enhancing the Efficacy of the Vaccine Mycobacterium Bovis BCG
Infectious Diseases Isaac-Renton Grant CIHR Doctoral Research Award 2,000
Molecular epidemiology of giardia lamblia in British Columbia's water supplies
Infectious Diseases Nandan Contract Pacific Pharma Technologies Inc. 16,500
Screening Assays and Consulting Services
Infectious Diseases Patrick Grant MSFHR - HSPR Operating Grant - Full Application
49,838
Changing Prescription Practices to Limit Selection for Resistant Organisms: A Population and System Approach
Infectious Diseases Patrick Grant Provincial Health Services Authority 62,000
Research operating account
Infectious Diseases Patrick Grant CIHR: HIV/AIDS Research Program 96,988
Development of an HIV/AIDS Prevention Intervention for Indoor Sex Workers and Their Partners
UBC Department of Medicine Page 24 Annual Report 2007
Infectious Diseases Patrick Grant CIHR Doctoral Research Award IDR-76898 (Fellow: McCarthy, Sheila)
1,000
Salary-HIV and Hepatitis C transmission networks in a cohort of injection drug users in Vancouver's downtown eastside: How structure and context matter
Infectious Diseases Phillips Clinical Trial BioAlliance Pharma 3,444
BA/2004/01/04: A Comparative Randomized, Double-Blind, Double-Dummy, Multicenter Study of the Efficacy and Safety of Miconazole Lauriad(R) 50mg Administered Once a Day and Mycelex(R) Troches (Clotrimazole 10mg) Administered Five Times a Da
Infectious Diseases Reiner Grant CIHR: Institute of Infection and Immunity -- Operating Grant
97,451
Macrophage cell regulation
Infectious Diseases Reiner Contract Genome British Columbia - Full Proposal
1,790,826
Functional Genomics for Emerging Infectious Diseases
Infectious Diseases Reiner Grant MSFHR: Junior Graduate Studentship Award ST-JGS-094(05-1)BM (Fellow: Thi, Emily)
2,500
Identification of Mycobacterium Tuberculosis Virulence Effector Proteins by Pathogen Effector Protein Screening in Yeast
Infectious Diseases Reiner Grant VCHA - Venture Grants (VGH & UBC Foundation In It For Life)
30,000
Identification of M.Tuberculosis and Chlamydia Trachomatis Effector Proteins Using a Genetic Screen in Yeast
Infectious Diseases Reiner Grant VCHA - Bridge Funding 10,000
Macrophage cell regulation
Infectious Diseases Reiner Grant VGH and UBC Hospital Foundation 98,000
PREPARE Project
Infectious Diseases Bowie Grant Vancouver Coastal Health Research Institute (VCHRI) - Team Grants
29,400
Incision and Drainage Alone vs Incision and Drainage and Trimethoprim-Sulfamethoxazole/Rifampin for Soft Tissue Abscesses Caused by Community Associated…
Infectious Diseases Steiner Grant Crohn's and Colitis Foundation of Canada
97,000
The Role of Bacterial Flagellin as an Inflammatory Stimulus in INflammatory Bowel Disease
Infectious Diseases Steiner Grant VCHA - Venture Grants (VGH & UBC Fdn In It For Life)
29,755
Establishment of a Rodent Model of Enteroagregative Escherichia Coli Enterocolitis
Infectious Diseases Steiner Grant CIHR Operating Grant MOP-64355 in collaboration w/ The Institute of Infection and Immunity (CIHR)
78,436
Mechanisms of toll-like receptor-5 signaling in response to bacterial Flagellin
Infectious Diseases Steiner Grant CIHR New Investigator 58,500
Mechanisms of Innate Immune Signaling by Enteroaggregative E. coli Flagellin
Infectious Diseases Steiner Grant CIHR 50,000
New emerging team grant in clinical autoimmunity
Infectious Diseases Tyndall Clinical Trial Merck and Co. Inc. 281,340
Protocol V520-023 A Multicenter, Double-Blind, Randomized, Placebo-Controlled, Phase II Proof-of-Concept Study to Evaluate the Safety and Efficacy of a 3-Dose Regimen of the Merck Adenovirus Serotype 5 HIV-1 gag/pol/nef Vaccine (MRKAd5 HIV
UBC Department of Medicine Page 25 Annual Report 2007
Infectious Diseases Tyndall Grant MSFHR: Junior Graduate Studentship Award ST-JGS-401(05-1)POP (Fellow: Berkhout, Susan)
1,500
Life at the margins: Understanding social determinants of HIV/AIDS on Women's Health through multidisciplinary translational research
Infectious Diseases Tyndall Grant MSFHR: Postdoctoral Trainee Fellowship ST-PDF-435(05-1)POP (Fellow: Orchard, Treena)
10,472
To each her own: sex work typologies, intimate relationships, and their impact on HIV risk for female sex workers in Vancouver DTES
Infectious Diseases Tyndall Grant MSFHR: Senior Graduate Studentship Award ST-SGS-473(05-1)POP (Fellow: Small, William)
3,417
An examination of injection drug use sites: the influence of social and physical context upon drug-related harms and public health interventions
Infectious Diseases Tyndall Grant CIHR: Strategic Training Program Grant - Institute of Aging
310,500
UBC Training program for translational research in infectious diseases
Infectious Diseases Tyndall Grant CIHR: HIV/AIDS Research Program 90,420
MAKA Initiative: HIV prevention and care among women survival sex workers
Infectious Diseases Tyndall Grant MSFHR Senior Scholar Award CI-SSH-097 (05-1)HSR
100,000
An interventional HIV research program to reduce transmission and enhance antiretroviral treatment outcomes among highly marginalized populations
Infectious Diseases Tyndall Grant British Columbia Centre for Excellence in HIV/AIDS
125,157
Salary support for Dr. Mark Tyndall
Infectious Diseases Tyndall Grant CIHR: HIV/AIDS Research Program 249,033
Enhancing the uptake and sustainability of HIV care & antiretroviral therapy among survival sex workers
Infectious Diseases Tyndall Grant CIHR Doctoral Research Award IDR-80936 (Fellow: Small, William)
1,000
Examination of injection drug use sites: the influence of social and physical context upon HIV risk, drug-related harms and public health interventions
Medical Oncology Gelmon Grant Michael Smith Foundation for Health
Research: Postdoctoral Trainee Fellowship (Fellow: Lane, Kirstin)
24,375
Effect of Chronic Exercise on Lymphatic Function
Medical Oncology Gill Grant Canadian Institutes of Health Research (CIHR): CIHR Rx & D Research Program - Fellowships (Fellow: Lim, Howard)
5,000
Research allowance: A phase II study of second line Sunitinib in previously treated patients with unresectable locally advanced or metastatic pancreatic cancer
Medical Oncology Gill Grant Canadian Institutes of Health Research (CIHR): CIHR Rx & D Research Program - Fellowships (Fellow: Lim, Howard)
32,500
Salary: A phase II study of second line Sunitinib in previously treated patients with unresectable locally advanced or metastatic pancreatic cancer
Medical Oncology Klimo Clinical Trial Novartis Pharmaceuticals Canada Inc.
9,542
A Randomized, Multicenter Study Comparing Prolonged Primary Systemic Endocrine Therapy with Letrozole (Femara) Alone or in Combination with Zoledronic Acid (Zometa) in Early Breast Cancer (NEOadjuvant study in CANada)
UBC Department of Medicine Page 26 Annual Report 2007
Medical Oncology Klimo Agreement Bayer Pharmaceuticals 14,891
Protocol 11961: A Randomized, Controlled Trial Comparing Safety and Efficacy of Carboplatin and Paclitaxel plus or minus Sorafenib (BAY 43-90006) in chemonaive Patients with Stage IIIB-IV Non-Small Cell Lung Cancer (NSCLC)
Nephrology Chiu Clinical Trial AstraZeneca Canada Inc.
4,240 Protocol PLANET II: Prospective Evaluation of Proteinuira and Renal Function in Non-Diabetic Patients With Progressive Renal Disease
Nephrology Chiu Clinical Trial AstraZeneca Canada Inc. 2,943
A double-blind, randomised, dose-ranging, multicentre, Phase III-b study to evaluate the efficacy and safety of high doses of candesartan cilexetil (Atacand)on the reduction of proteinuria in the treatment of subjects with hypertension and…
Nephrology Chiu Clinical Trial AstraZeneca Canada Inc. 4,240
Protocol PLANET I: Prospective Evaluation of Proteinuria and Renal Function in Diabetic Patients With Progressive Renal Disease
Nephrology Duncan Clinical Trial AstraZeneca Canada Inc. 2,730
4522IL/0096 (AURORA) A Study to Evaluate the Use of Rosuvastatin in Subjects On Regular Haemodialysis: An Assessment of Survival & Cardiovascular Events: Double-blind Randomized Multicentre Phase III-b Parallel-group Study to Compare the ....
Nephrology Duncan Clinical Trial Merck and Co. Inc. 14,751
SHARP: Study of Heart and Renal Protection
Nephrology Gill Clinical Trial Novartis Pharmaceuticals Canada Inc.
3,000
Protocol MyGain: A 4-week, Multicenter, Double-blind, Randomized, Parallel-group Study to Compare the Gastrointestinal Safety and Tolerability of Myfortic and MMF (Cellcept) when Administered in Combination with Calcineurin Inhibitors in…
Nephrology Gill Clinical Trial Novartis Pharmaceuticals Canada Inc.
46,157
A 24-week Feasibility Study to Evaluate Replacement of Calcineurin Inhibitor (CNI) With Simulect In CNI Intolerant Long-term Kidney Transplant Recipients Treated With Mycophenolic Acid and Steroids (REPLACE study)
Nephrology Gill Clinical Trial CIHR Randomized Controlled Trials 7,000
IICT: ACE-Inhibition for the Preservation of Renal Function and Patient Survival in Kidney Transplantation
Nephrology Gill Grant MSFHR Scholar Award 80,000
Access to kidney transplantation in B.C. and Alberta
Nephrology Gill Grant CIHR Operating Grant 107,149
Access to kidney transplantation in B.C. and Alberta
Nephrology Gill Grant Canadian Institutes of Health Research
5,850
The Long-term Medical and Psychosocial Implications of Becoming a Living Kidney Donor: A Canadian Prospective Pilot Study
UBC Department of Medicine Page 27 Annual Report 2007
Nephrology Jung Clinical Trial St. Joseph's Hospital and Medical Center
5,436
IICT: A Randomized Controlled Trial of Mycophenolate Mofetil in Patients with IgA Nephropathy (MMF/IgAN Study)
Nephrology Jung Clinical Trial AstraZeneca UK Ltd. 6,897
(AURORA) A double blind, randomised, multicentre, phase III-b, parallel-group study to compare the effects of Rosuvastatin (10mg oral) with placebo on assessment of survival and cardiovascular events when given to subjects with end-stage renal failure on chronic haemodialysis treatment
Nephrology Keown Contract Genome British Columbia 329,918
CRA: Better Biomarkers of Acute and Chronic Allograft Rejection
Nephrology Keown Grant CIHR: Partnership for Health System Improvement PHE-81967
75,000
A pilot project for health systems improvement to facilitate live donor and pre-emptive renal transplantation in chronic kidney disease
Nephrology Keown Clinical Trial Novartis Pharmaceuticals Canada Inc.
3,624
CERL080AUS51: A 4 Week, Multicenter, Double-Blind, Randomized, Parallel Group Study to Compare the Gastrointestinal Safety and Tolerability of Myfortic and MMF (Cellcept) when Administered in Combination with Calcineurin Inhibitors in Renal
Nephrology Keown Contract Providence/ St. Paul's Hospital Foundation
70,935
Better Biomarkers in Transplantation
Nephrology Kiaii Clinical Trial Hoffmann-La Roche Ltd. (Canada) 11,971
Short Title: CERA for Hemodialysis Population (version 1.1) A Randomized, Controlled, Open-Label, Multi-Center, Parallel-Group Study to Compare the Efficacy and Safety of RO0503821 With That of Darbepoetin Alfa Administered Intravenously
Nephrology Kiaii Clinical Trial University of Calgary 4,857
IICT: Prevention of Catheter Lumen Occlusion with rT-PA (Recombinant Tissue Plasminogen Activator) Versus Heparin (Pre-CLOT): A Double Blind Randomized Trial
Nephrology Levin Grant Canadian Institutes of Health Research
160,232
Canadian Prevention of Renal and Vascular Endpoints Trial
Nephrology Levin Clinical Trial Janssen-Ortho Inc. 15,000
A study to determine the impact of Hgb maintenance and other interventional strategies to prevent or delay the progression of left ventricular mass growth in subjects with early renal insufficiency
Nephrology Levin Grant Ortho Biotech 1,250
IICT:REPEAT Study: Resistance to Erythropoetin Effectiveness Algorithm Trial
Nephrology Levin Clinical Trial Genzyme Corp. 30,000
IICT: Peritoneal Dialysis Research Program
Nephrology Levin Grant Various Sources 31,000
NERC
UBC Department of Medicine Page 28 Annual Report 2007
Nephrology Levin Clinical Trial Merck and Co. Inc. 247,848
Study of Heart and Renal Protection (SHARP)
Nephrology Quamme Grant CIHR Operating Grant 100,000
Studies of Renal Magnesium Transport
Nephrology Shapiro Clinical Trial Wyeth Research 10,926
0468H1-407-WW: A Randomized, Open-Label Study to Compare the Rate of New Non-Melanoma Skin Cancer in Maintenance Renal Allograft Recipients Converted to a Sirolimus-based Regimen versus Continuation of a Calcineurin Inhibitor-based Regimen
Nephrology Wong Grant Show Chwan/VHHSC Fund 52,891
Vasoactive peptides in congestive heart failure
Nephrology Yeung Clinical Trial St. Joseph's Hospital and Medical Center
3,789
IICT: A Randomized Controlled Trial of Mycophenolate Mofetil in Patients with IgA Nephropathy
Neurology Barton Grant CIHR Operating Grant MOP-81270
73,587 The context and effects of trial history on saccades and their status in neurological disorders
Neurology Barton Grant Canada Research Chair Tier II (CIHR) 950-202111
100,000
Canada Research Chair for Dr. Jason Barton in Neuropsychology of vision and eye movements
Neurology Barton Grant National Institutes of Health 5R01MH069898-05
325,044
Perceptual encoding and imagery in prosopagnosia
Neurology Barton Grant MSFHR Senior Scholar Award CI-SSH-035(03-1) CLIN
15,000
Neuropsychology of vision and eye movements
Neurology Barton Grant MSFHR Postdoctoral Trainee Fellowship ST-PDF-180(06-1)CLIN (Fellow: Iaria, Giuseppe)
21,208
Topographical disorientation as a predictor of Alzheimer's Disease in patients affected by mild cognitive impairment
Neurology Barton Grant MSFHR Postdoctoral Trainee Fellowship ST-PDF-339(05-1)CLIN (Fellow: Wieske, Van Zoest)
32,500
Stimulus-driven Control in Visual Neglect: The Role of Awareness
Neurology Barton Grant CIHR: Doctoral Research Awards CGD-80369 (Fellow: Fox, Christopher)
5,000
Facial identity and expression perception following cerebrovascular infarction
Neurology Barton Grant CIHR Operating Grant MOP-77615 101,312
Processing of face recognition in patients with occipitotemporal lesions after posterior cerebral infarction
Neurology Barton Grant Canadian Institutes of Health Research (CIHR)
60,000
Face expression and identity processing in the occipitotemporal cortex
Neurology Barton Grant BC Network for Aging Research 4,900
Navigating in the elderly: Behavioural and MRI correlates of aging effects on cognitive maps
Neurology Barton Grant Department of Medicine Academic Enhancement Fund
29,453
Interactive case-based approach to neuro-ophthalmologic education on the internet
Neurology Cashman Contract Pall Corporation 39,000
Detection of Prions in Blood
UBC Department of Medicine Page 29 Annual Report 2007
Neurology Cashman Grant PrioNet - Networks of Centres of Excellence (NCE)
270,000
Immunotheraphy of CJD
Neurology Cashman Grant Donation 557,000
Allen T. Lambert Neural Research Fund: ALS Transplantation
Neurology Cashman Grant PrioNet - Networks of Centres of Excellence (NCE)
304,160
Pathogenesis & Bioassay Platform
Neurology Cashman Contract Amorfix Life Sciences Ltd. 300,000
Prion-like misfolding of Superoxide Dismutase I in Amyotrophic Lateral Sclerosis
Neurology Cashman Grant UBC VPR Research Development Fund & VCHA
126,240
UBC PrioNet Canada operation support
Neurology Cashman Grant Canada Research Chair Tier I (CIHR) 200,000
Canada Research Chair in Neurodegeneration and Protein Misfolding Diseases for Dr. Neil Cashman
Neurology Chapman Agreement Pfizer Canada Inc. 13,808
Protocol A0081064: A 9-week, randomized, double-blind, placebo-controlled, multicenter, study of Pregabalin (BID) in subjects with posttraumatic peripheral neuropathic pain
Neurology Chapman Clinical Trial Takeda Global Research and Development
39,588
01-05-TL-128-006 An Open-label, multi-centre Study to Evaluate the Safety of Long-term Administration of TAK28 in Subjects with Mild to Moderate Diabetic Peripheral Neuropathy
Neurology Chapman Clinical Trial Wyeth-Ayerst Canada Inc. 325
Protocol 0912A2-212-NA: Multicenter Randomized Double-blind Placebo-controlled Study of 3 Fixed Doses of EAA-090 in Adult Outpatients with Neuropathic Pain Associated with Diabetic Neuropathy
Neurology Chapman Agreement Takeda Global Research and Development
161,248
01-06-TL-583-006: A Phase 2, Randomized, double-Blind, Placebo-Controlled, Dose Ranging, Study to Evaluate the Efficacy and Safety of 3 Doses of TAK-583 in Subjects with Mild to Moderate Diabetic Peripheral Neuropathy
Neurology Devonshire Grant Health Science Donations 5,000
MS COSTAR Data Entry for the Genetic Susceptibility to MS Study
Neurology Devonshire Clinical Trial Novartis Pharmaceuticals Canada Inc.
140,041
CFTY720D2301: A 24-Month, Double-blind, Randomized, Multicenter, Placebo-controlled, Parallel-group Study comparing Efficacy and Safety of FTY720 1.25mg and 0.5 mg Administered Orally Once Daily vs. Placebo in Patients with Rel/rem MS
Neurology Devonshire Clinical Trial Novartis Pharmaceuticals Canada Inc.
14,690
CFTY720D2201E1: Ext. to CFTY720D2201: Extension of the Double-blind, Randomized, Placebo-controlled, Parallel-group, Multicentre Study Evaluating Safety Tolerability & Effect on MRI Lesion Parameters of FTY720 vs Placebo in Patients with Relapsing..
UBC Department of Medicine Page 30 Annual Report 2007
Neurology Devonshire Clinical Trial GW Pharmaceuticals PLC 5,965
GWMS0501: A Double-blind, Randomised, Placebo-controlled, Parallel-group Study of Sativex when added to the Existing Treatment Regimen in the Relief of Central Neuropathic Pan in Subjects with Multiple Sclerosis
Neurology Devonshire Clinical Trial Novartis Pharmaceuticals Canada Inc.
150,722
CFTY: 720D2302 A 12 month Double-blind, Randomized, Multicenter, Active-controlled, Parallel-group Study Comparing the Efficacy and Safety of 0.5mg and 1.25 mg Fingolimod (FTY720) Administered Orally Once Daily vx. Interferon B-1a...
Neurology Devonshire Clinical Trial Biogen Idec Inc. 50,842
101-MS-322: An Open-label, Multicenter Extension Study to Evaluate the Safety and Tolerability of Natalizumab Following Re-initiation of Dosing in Multiple Sclerosis Subjects who have Completed Studies C1801, C-1802, or C-1803 and ......
Neurology Doudet Contract Bayer HealthCare Pharmaceuticals Inc. USA
179,370
In vivo PET and behavioural study of the effect of striatal implantation of Retinal Pigment Epithelial cells in a primate model of Parkinson' disease
Neurology Doudet Grant Parkinson Society Canada: Basic Research Fellowship (Fellow: Landau, Anne)
13,333
Evaluation of the role of monoamines in electroconvulsive therapy in an animal model of Parkinson's Disease
Neurology Doudet Grant CIHR Team Grant Program CTP-79851
84,588
CIHR Team in Parkinson's Disease: Core D - Animal Core
Neurology Doudet Grant MSFHR Senior Graduate Studentship Award ST-SGS-367(06-1)BM (Fellow: Flores, Joe)
2,500
In Vivo Evaluation of the Potential Role of Anti-inflammatory Factors Involved in the Survival and Mechanism of Action of hRPE-Cell Implants for Parkinson's Disease
Neurology Feldman Grant MSFHR Senior Graduate Studentship Award ST-SGS-350(05-1)CLIN (Fellow: LaMarre, Amanda)
2,500
Cognitive and Behavioural Characterization of Individuals Genetically at Risk for Frontotemporal Dementia
Neurology Feldman Grant Lundbeck Canada Inc. 40,780
Clinical Meaningfulness In Alzheimer's Disease Treatment (CLIMAT) Scale
Neurology Feldman Grant CIHR Operating Grant MOP-74580 371,299
Frontotemporal dementia with ubiquinated inclusions: Clinical, genetic, and pathological characterization
Neurology Feldman Clinical Trial ONO Pharma USA Inc. 2,931
ONO-2506POU010: Double-blind, Phase II Safety and Efficacy Evaluation of ONO-2506PO in Patients with Mild to Moderate Alzheimer's Disease
Neurology Feldman Grant VCHA Venture Grants 29,780
Development of the Clinical Meaningfulness in Alzheimer Disease (CLIMAT) Scale
Neurology Feldman Clinical Trial Sanofi-Synthelabo Canada Inc. 23,270
LTS5283: Long-Term Safety Extension of Phase II Study EFC5286 of SR57667B in Patients with Mild-to-Moderate Alzheimer's Disease
UBC Department of Medicine Page 31 Annual Report 2007
Neurology Feldman Agreement Myriad Genetics Inc. 27,666
MPC-7869-05-010: Phase 3 Multinational, Randomized, Double-Blind, Placebo Controlled Study of the Effect of Daily Treatment with MPC-7869 on Measures of Cognition, Activities of Daily Living and Global Function in Subjects with Mild Dementia
Neurology Feldman Agreement GlaxoSmithKline (Canada) Inc. 3,000
AVA102670: (REFLECT-3) A 54-week Double-blind, Randomized, Placebo-controlled, Parallel-group Study to Investigate the Effects of Rosiglitazone (extended release tablets) as Adjunctive Therapy to Acetycholinesterase Inhibitors on Cognition
Neurology Feldman Grant Alzheimer Society & Mr David Townsend
100,000
Alzheimer Research
Neurology Feldman Grant Alzheimer Society of BC Professorship
48,925
Alzheimer Research
Neurology Feldman Clinical Trial National Institutes of Health 53-00-ADNI-PIB
1,945
IICT (Gov't.): Alzheimer Disease Neuroimaging Initiative (ADNI)
Neurology Gibson Clinical Trial Eli Lilly Canada Inc. 785
Protocol B7A-MC-MBBR: LY333531 Treatment of Peripheral Neuropathy in Patients with Diabetes: A Phase 3 Pivotal Clinical Trial
Neurology Hashimoto Grant Donations for Health Science Research
1,250
Clinical Research in Multiple Sclerosis
Neurology Illes Grant Canada Research Chair Tier I (CIHR) 150,000
Canada Research Chair in neuroethics for Dr. Judy Illes
Neurology Illes Grant Canada Foundation for Innovation 349,967
National Core for Integrated Neuroethics in Canada (NCINC) at UBC
Neurology Illes Grant Canadian Institutes of Health Research (CIHR)
266,666
National core for integrated neuroethics in Canada (NCINC)
Neurology Illes Grant Foundation for Ethics and Biotechnology
55,000
Bioethical Landscape of Neurodegenerative Diseases Research and Treatment
Neurology Johnston Clinical Trial NMT Medical Inc. 10,000
A prospective, multicenter, randomized, controlled trial to evaluate the safety and efficacy of the Starflex (R) septal closure system versus best medical therapy in patients with a stroke and/or transient ischemic attack due to presumed pa
Neurology Kastrukoff Grant Canadian Institutes of Health Research (CIHR)
98,400
Natural killer (NK) and natural killer T (NKT) cells in Herpes simplex virus Type 1 (HSV 1) infections in mice
Neurology Kastrukoff Clinical Trial Teva Neuroscience Inc. (US) 8,418
GA9016: A Multinational, Multicenter, Randomized, Parallel-Group, Double-Blind Study, to Compare the Efficacy, Tolerability and Safety of Glatiramer Acetate Injection 40mg/ml to that of Glatiramer Acetate Injection 20mg/ml Administered...
UBC Department of Medicine Page 32 Annual Report 2007
Neurology Kastrukoff Grant Donations for Health Science Research
300
Virology Research
Neurology Krieger Clinical Trial Sanofi Pasteur Ltd. 11,400
Long term safety and tolerability study of SR57746A in patients with Amyotrophic Lateral Sclerosis
Neurology McKeown Grant Natural Sciences and Engineering Research Council of Canada (NSERC)
54,988
Making the connection: methods to infer functional connectivity in brain studies
Neurology McKeown Agreement National Parkinson Foundation (US) 67,523
01 Account- Designation as an National Parkinson Foundation, Centre of Excellence
Neurology McKeown Grant Michael Smith Foundation for Health Research
1,458
Dynamic suppression of pathological brain oscillations in Parkinson's disease with virtual environments
Neurology McKeown Grant NSERC/CIHR: Collaborative Health Research Projects CHRPJ 323602-06 with SFU
54,988
Making the connection: methods to infer functional connectivity in brain studies
Neurology McKeown Grant CIHR: Doctoral Research Awards CGD-80403 (Fellow: Palmer, Samantha)
5,000
Research Allowance - Changes in effective connectivity in Parkinson's Disease: Disentangling compensatory mechanisms from effects of disease
Neurology Oger Grant Dr. Schlegel Healthworld AG 30,000
Setting-up, validating and evaluating the clinical usefulness of laboratory tests to measure antibodies to interferon in multiple-sclerosis patients
Neurology Oger Clinical Trial BioMS Technology Corp. 113,063
MBP8298-SP-02: An Open-label Follow-up Study to Assess the Ongoing Safety of MBP8298 in Subjects with Secondary Progressive Multiple Sclerosis
Neurology Oger Clinical Trial BioMS Technology Corp. 329,111
MBP8298-01: A Double-blind, Placebo-controlled, Multicenter Study to Evaluate the Efficacy and Safety of MBP8298 in Subjects with Secondary Progressive Multiple Sclerosis
Neurology Oger Clinical Trial ACORDA Therapeutics MS-F203 EXT
35,095
MS-F203 Extension Study: An Open-label Extension Study to Evaluate the Safety, Tolerability and Activity of Oral Fampridine-SR in Subjects with MS who Participated in the MS-F203 Trial
Neurology Oger Clinical Trial Various Pharmaceutical Companies 57,313
Setting-up, Validating and Evaluating the Clinical Usefulness of Laboratory Tests to Measure Antibodies to Interferon in Multiple Sclerosis Patients
Neurology Oger Grant Multiple Sclerosis Society of Canada: Career Development Award for Helen Tremlett
50,000
The MaMS Study, Malignancy and Multiple Sclerosis: incidence and impact of beta-interferon treatment
Neurology Oger Grant Donations for Health Science Research
7,170
Myasthenia Gravis Research
Neurology Rieckmann Grant Multiple Sclerosis Society Chair Endowment
500,000
New faculty start-up funds - MS Research Program
UBC Department of Medicine Page 33 Annual Report 2007
Neurology Ruth Grant CIHR Operating Grant MOP-67007 69,042
Development of Radiotracers Based on Oligonucleotide Labelling
Neurology Ruth Grant CIHR: Combined multi-user Equipment/ Maintenance PRG-81042
85,645
Maintenance for the UBC PET scanners
Neurology Ruth Grant CIHR Team Grant Program 286,247
CIHR Team in Parkinson's Disease-Core (C-Imaging Core)
Neurology Sossi Grant CIHR Operating Grant MOP-74638 294,993
In-vivo studies on disease and treatment-induced changes of levodopa-derived dopamine kinetics and DA transporter expression using a Parkinson's Disease rat model and a microPET
Neurology Spacey Grant National Ataxia Foundation 28,486
The role of P/Q type calcium channels in the pathogenesis and treatment of ataxia
Neurology Stoessl Grant Canada Research Chair Tier I (CIHR) 100,000
Canada Research Chair Tier I in Parkinson's Disease for Dr. Jon Stoessl
Neurology Stoessl Clinical Trial Kyowa Pharmaceutical Inc. 21,662
Protocol 6002-US-025: An Open-label, Multicentre Study of the Continued Safety of Istradefylline in Subjects with Parkinson's Disease who have Recently Completed One Year of Treatment with Istradefylline
Neurology Stoessl Grant Pacific Parkinson's Research Institute 100,000
James A. Moore Chair in Parkinson's research
Neurology Stoessl Clinical Trial Ceregene Inc. 192,984
PET Scanning in Association with a Phase I Open-label study of CERE-120 (Adeno-Associated Virus Serotype 2[AAV2]-Neurtuin [NTN]) to Assist the Safety and Tolerability of Intrastriatal Delivery to Subjects with Idiopathic Parkinson's Disease
Neurology Stoessl Grant CIHR Operating Grant MOP-15127 58,427
The natural history of sporadic and inherited Parkinson's Disease
Neurology Stoessl Grant MSFHR: Research Unit Infrastructure Support Program IN-RU-A-007(05-1)
200,000
MSFHR research unit in Parkinson's Disease and monoaminergic function in the central nervous system
Neurology Stoessl Grant Michael Smith Foundation for Health Research
1,042
The roles of expectation and dopamine in the placebo effect in Parkinson's Disease
Neurology Stoessl Clinical Trial Sanofi-Synthelabo Canada Inc. 24,486
Protocol ACT5288:Phase II Randomized Multicentre Multinational Double-Blind Placebo-Controlled Study of the Effect of SR57667B on Dopaminergic Nigro-Striatal Function Assessed by 18F-Dopa PET Imaging in Outpatients with Early Parkinson's...
Neurology Stoessl Clinical Trial Kyowa Pharmaceutical Inc. 17,399
6002-INT-001: A Long-term Multicenter Open-label Study with Oral 20 or 40 mg/doses of KW-6002 (Istradefylline) as Treatment for Parkinson's Disease in Patients With Motor Response Complication on Levodopa Therapy
UBC Department of Medicine Page 34 Annual Report 2007
Neurology Stoessl Grant CIHR Operating Grant MOP-15126 148,157
Complications of Parkinson's Disease: The dopaminergic basis of depression
Neurology Stoessl Agreement National Parkinson Foundation (US) 76,140
National Parkinson Foundation, Centre of Excellence
Neurology Stoessl Grant Pacific Alzheimer Research Foundation
1,050,860
Overlap syndromes resulting in dementia
Neurology Stoessl Grant CIHR Team Grant CTP-79851 116,822
CIHR team in Parkinson's Disease: Core A - Clinical & Administrative Core
Neurology Stoessl Grant CIHR Team Grant CTP-79851 67,747
CIHR Team in Parkinson's Disease: Core B - Biostatistics & Mathematical modeling
Neurology Stoessl Grant CIHR Team Grant CTP-79851 216,651
CIHR Team Grant in Parkinson's Disease
Neurology Stoessl Grant MSFHR Senior Graduate Studentship Award ST-SGS-182(06-1)CLIN (Fellow: Lidstone, Sarah)
1,458
The effect of reward expectation and dopamine release on the mechanism of the placebo effect in Parkinson's Disease
Neurology Stoessl Contract Ceregene Inc. 80,799
PET Scanning in Assoc with a Multi-Center, Randomized, Double-Blind, Sham surgery controlled Study of CERE-120 (Adeno Associated Virus Serotype 2 {AAV2}-Neurturin {NTN} to Assess the Efficacy and Safety of Bilateral Intraputaminal (IPu) ...
Neurology Teal Clinical Trial Vernalis Ltd. 10
V10153-2S-01: A Phase II Multicenter Two-Part Study to Evaluate the Safety and Efficacy of V10153 in Acute Ischemic Stroke
Neurology Teal Clinical Trial National Institutes of Health 10,565
IICT : CREST - Carotid Revascularization Endarterectomy vs. Stenting Trial
Neurology Teal Clinical Trial Canadian Institutes of Health Research (CIHR)
1,350
FASTER: Fast Assessment of Stroke and Transient Ischemic Attack to Prevent Early Recurrence Trial
Neurology Teal Clinical Trial Boehringer Ingelheim (Canada) Ltd. 40,482
9.159 PROFESS: Prevention Regimen for Effectively Avoiding Second Strokes: A Double-Blind Active and Placebo Controlled Study of Aggrenox vs Clopidogrel and Aspirin with and without Micardis
Neurology Teal Agreement Servier Canada 49,645
CL3-18886-012 (The Perform Study) prevention of cerebrovascular and cardiovascular events of ischaemic origin with teRutroban in patients with a history of ischaemic stroke or transient ischaemic attack
Neurology Teal Clinical Trial NMT Medical Inc. 39,717
G980031 CLOSURE 1: Prospective Multicenter Randomized Controlled Trial to Evaluate the Safety and Efficacy of the STARFlex Septal Closure System vs Best Medical Therapy in Patients with a Stroke and/or Transient Ischemic Attack Due to Pre..
Neurology Teal Clinical Trial Forest Laboratories Inc. 3,000
PN01-01/CD 003 DIAS-2: Desmoteplase (INN) in Acute Ischemic Stroke Phase III
UBC Department of Medicine Page 35 Annual Report 2007
Neurology Teal Clinical Trial National Institutes of Health 21,578
IICT: Albumin in Acute Stroke (ALIAS) Trial
Neurology Teal Agreement Sanofi-Aventis Canada Inc. 5,460
CASTIA, PM-C-0225: Randomized, Double-Blind Study Comparing the Effect of a 3-Month Clopidogrel Regimen, Combined with ASA the First Month, Versus ASA Alone for the Acute Treatment of TIA/Minor Stroke Patients
Neurology Traboulsee Clinical Trial Centocor Inc. 1,551
C0743T06: A Phase II Double-Blind Placebo-Controlled Randomized Dose-Ranging Study of Multiple Subcutaneous Injections of Human Monoclonal Antibody to IL-12p40 (CNTO 1275) in Subjects with Relapsing-Remitting Multiple Sclerosis
Neurology Traboulsee Clinical Trial Bayer Inc. (Canada). 6,500
Protocol 309363: International, Multicenter, Phase IIIb Study of Subcutaneous Every-Other-Day Treatment of Patients with Relapsing Multiple Sclerosis with (Phase A) Double-Blind Betaseron/Betaferon 250ug or 500 ug or ...
Neurology Traboulsee Clinical Trial Berlex Canada Inc. 81,861
306440 BEYOND Study: International Randomized Multicenter Phase 3b Study in Patients with Relapsing-Remitting Multiple Sclerosis Comparing Over a Treatment Period of 104 Weeks: Double-Blinded SafetyTolerability and Efficacy of Betaseron/B..
Neurology Traboulsee Clinical Trial Transition Therapeutics and Diagnostics Inc.
44,586
IET-2O1: Open Label Baseline-to-Treatment Crossover Clinical Trial to Evaluate the Safety Tolerability Pharmacokinetics & Effects of Vitamin B12 When Used in Combination with Interferon-b Treatment in Patients with Relapsing Remitting MS...
Neurology Traboulsee Clinical Trial Genentech Inc. 59,694
U2786g: Phase II/III Randomized Double-Blind Parallel-Group Placebo-Controlled Study to Evaluate the Safety and Efficacy of Rituximab in Adults with Primary-Progressive Multiple Sclerosis (PPMS)
Neurology Traboulsee Clinical Trial Aventis Pharma Inc. 29,509
Protocol HMR1726D/2002: Extension of Protocol HMR1726D/2002, A Phase II Study of the Safety & Efficacy of Teriflunomide (HMR1726) in Multiple Sclerosis with Relapses
Neurology Traboulsee Clinical Trial Sanofi-Aventis Canada Inc. 106,119
A Randomized, Double-blind, Placebo-controlled, Parallel-group, Design Study to Evaluate the Efficacy and Safety of Teriflunomide (HMR1726D) in Reducing the Frequency of Relapses and Delaying the Accumulation of Physical Disability…
Neurology Traboulsee Clinical Trial ACORDA Therapeutics 10,799
MS-F204: Double-Blind, Placebo-Controlled, 13-Week, Parallel Group Study to Evaluate Safety and Efficacy of Oral Fampridine-SR (10mg b.i.d.) in Patients with Multiple Sclerosis
UBC Department of Medicine Page 36 Annual Report 2007
Neurology Traboulsee Clinical Trial Abbott Laboratories Ltd. (Canada) 3,543
M03-654: A 24-week, Randomized, Double-blind, Parallel-group, Placebo-controlled, Dose-finding, Safety, Tolerability & Efficacy Study of the Human Anti-IL-12 Antibody ABT-874 in Subjects with Multiple Sclerosis with a 24-week Double-blind Active ...
Neurology Traboulsee Clinical Trial Sanofi-Aventis Canada Inc. 30,546
Long-term Extension of the Multinational, Double-blind, Placebo-controlled Study EFC6049 (HMR 1726D/3001) to Document the Safety of Two Doses of Teriflunomide (7 & 14mg) in Patients with Multiple Sclerosis with Relapses
Neurology Tremlett Grant National Multiple Sclerosis Society (US)
52,376
Do relapses effect disease progression? New perspectives on the natural history of MS from British Columbia
Neurology Tremlett Grant CIHR Operating Grant MOP-82738 38,389
The MaMS Study, Malignancy and Multiple Sclerosis: incidence and impact of beta-interferon treatment
Neurology Tremlett Grant Multiple Sclerosis Society of Canada 50,000
Don Paty Career Development Award
Neurology Tremlett Grant MSFHR Scholar Award CI-SCH-119(06-1)
33,750
The MaMs study. Malignancy and Multiple Sclerosis: incidence and impact of beta-interferon treatment
Neurology Tsui Clinical Trial Solstice Neuroscience Inc. 11,228
An Open Label Safety and Immunogenecity Study of MYOBLOC (NEUROBLOC; BOTULINIM TOXIN TYPE B) Injectable Solution in Patients with Cervical Dystonia
Neurology Tsui Clinical Trial Teva Neuroscience Inc. (Canada) 34,462
TVP-1012/500: A Multicenter, double-blind, randomized start, placebo-controlled, paralleled group study to assess Rasagiline as a disease modifying therapy in early Parkinson's disease subjects
Neurology Tsui Clinical Trial Eisai Medical Research Inc. 14,912
E2007-A001-302: A Multi-Centre, Randomized, Double-Blind, Placebo-Controlled, Parallel Group Study of the Efficacy, Safety, and Tolerability of E2007 in Levodopa Treated Parkinson's Disease Patients with Motor Fluctuations
Neurology Tsui Clinical Trial MERCK (Germany) 18,099
Protocol EMR 62 225-013 (SPIRID-O): An Open-Label Multicentre Multinational Follow-Up Study to Evaluate the Long-Term Safety & Maintenance of Efficacy of Sarizotan in Parkinson Patients with L-Dopa Induced Dyskinesia
Neurology Wang Grant (BRC) Canadian Institutes of Health Research (CIHR)
5,000
Research Allowance -- Animal modeling schizophrenia: A two-hit approach
Neurology Wang Grant (BRC) Canadian Institutes of Health Research (CIHR)
40,000
Salary: Animal modeling schizophrenia: A two-hit approach
Neurology Wang Grant (BRC) Various Sources 180,659
Molecular mechanisms of AMPA receptor cycling
Neurology Wang Grant (BRC) Michael Smith Foundation for Health Research
25,000
Postsynaptic regulation of neurotransmission
UBC Department of Medicine Page 37 Annual Report 2007
Neurology Wang Grant (BRC) Canadian Institutes of Health Research (CIHR)
171,021
Regulation of postsynaptic expression of GABA-A receptors
Neurology Wang Grant (BRC) NeuroScience Canada Foundation 110,000
Synaptic repair by peptides interfering with protein-protein interactions critical for synaptic plasticity and maturation: a rational pharmacology for restoring cognitive and emotional function
Neurology Wang Grant (BRC) Canadian Institutes of Health Research (CIHR)
143,065
AMPA receptor regulation and synaptic plasticity
Neurology Wang Grant (BRC) Howard Hughes Medical Institute 113,705
Investigation into the molecular mechanisms underlying synaptic plasticity
Neurology Wang Grant (BRC) Michael Smith Foundation for Health Research
4,083
A subunit-specific role for NMDA receptor antagonism in neonatal seizures: in vivo and in vitro characterization
Neurology Wang Grant MSFHR Junior Graduate Studentship Award ST-JGS-045(05-1)BM (Fellow: Lai, Ted)
1,042
Activation of NR2A-containing NMDA receptor-mediated cell survival as a novel and innovative therapeutic strategy in the treatment of a stroke
Neurology Wang Grant Canadian Stroke Network (CSN) - Networks of Centres of Excellence (NCE) Graduate Studentship RFD1147 (Fellow: Lam, June)
5,000
CSN Summer Studentship - Neurodegeneration following stroke
Neurology Wang Grant CIHR Doctoral Research Award CGD-83640 (Fellow: Lai, Ted)
5,000
Activation of NR2A-containing NMDA receptor-mediated cell survival as a novel and innovative therapeutic strategy in the treatment of stroke
Neurology Wang Grant Heart & Stroke Fdn of British Columbia and Yukon Program/ Project Grant
120,740
Investigation into the molecular mechanisms mediating excitotoxicity - developing novel post-stroke therapies
Neurology Wang Grant HSFC/ CSN/ CIHR Doctoral Research Award (Fellow: Ge, Yuan)
857
Research Allowance: Modulation of AMPA receptor trafficking in the animal model of stroke
Neurology Wang Grant NCE/ Canadian Stroke Network (CSN) - Research
83,000
NMDA: Treatment of stroke with peptide and small molecule inhibitors of NMDA receptor-PSD95 interaction
Neurology Woolfenden Clinical Trial Novo-Nordisk 50,638
F7ICH-1641: Factor VII (Niastase) in Acute Intracerebral Hemorrhage
Neurology Woolfenden Grant National Institutes of Health 2,728
WASID
Neurology Woolfenden Clinical Trial National Institutes of Health 29,280
IICT: Interventional Management of Stroke Study III
Physical Medicine & Rehabilitation
Dhawan Agreement Victhom Human Bionics 20,951
VHB-3015-PR01-v00: Pilot Study of Neurostep System in Patients with Gait Disorder Secondary to Central Nervous System Lesion
UBC Department of Medicine Page 38 Annual Report 2007
Physical Medicine & Rehabilitation
Hughes Agreement Coloplast Corp. 34,632
DKO46CC: A Prospective, Randomized, Parallel-group, Multicenter Study to Investigate Urinary Tract Infections in Patients with Spinal Cord Injury Using Either Coated or Uncoated Intermittent Catheters
Physical Medicine & Rehabilitation
Travlos Grant Allergan Inc. 10,000
Treatment of Thoracic Outlet Syndrome with Botulinum Toxin Injection: A Double-blind, Randomized, Controlled Trial
Physical Medicine & Rehabilitation
Van Rijn Grant Vancouver Coastal Health Authority
24,900
Salary: Research Nurse
Respiratory Medicine
Abboud Agreement Hoffmann-La Roche Ltd. (Canada) 45,000
PATIENT REIMBURSEMENT ACCOUNT FOR STUDY na17598
Respiratory Medicine
Abboud Agreement Hoffmann-La Roche Ltd. (Canada) 140,900
Protocol: NA17598D, A multicenter, double-blind, placebo-controlled randomized trial of the efficacy safety and tolerability of 12 months of once daily treatment with 5mg of RO3300074 in patients with symptomatic emphysema secondary to alphy…
Respiratory Medicine
Ayas Grant BC Lung Association: BC Lung/CIHR Investigator
6,250
Investigation of the diagnosis and treatment of sleep disordered breathing
Respiratory Medicine
Ayas Grant CIHR New Investigator 10,417
Investigation of the diagnosis and treatment of sleep disordered breathing
Respiratory Medicine
Ayas Grant MSFHR Scholar Award 65,417
The public health impact of obstructive sleep apnea hypopnea
Respiratory Medicine
Ayas Grant MSFHR HSPR Operating Grants Program - LOI
74,860
HSPRSN Investigative Teams development grant - Intensive Care Unit Patient Safety Team
Respiratory Medicine
Ayas Grant UBC Department of Medicine 25,000
The Public Health Impact of Obstructive Sleep Apnea Hypopnea (OSAH)
Respiratory Medicine
Bai Grant British Columbia Lung Association 30,000
Airway structural phenotypes in asthma
Respiratory Medicine
Bai Grant CIHR: Request for Proposal/Application
114,717
Environmental impact on the epithelial immune barrier in asthma
Respiratory Medicine
Bai Grant Astra Charnwood 98,489
Asthma Research Clinic
Respiratory Medicine
Bai Grant Allergy, Genes and Environment Network (AllerGen) - Networks of Centres of Excellence
55,000
Environmental impact on the epithelial immune barrier in asthma
Respiratory Medicine
Bai Clinical Trial Boehringer Ingelheim (Canada) Ltd. 12,375
Protocol 1222.6 (Project Nickname BI 1744 CL): A randomised, double-blind, placebo-controlled, parallel-group study to assess the efficacy (Bronchodilation) and safety of 4 weeks of once daily treatment of orally inhaled BI 1744 CL (2up, 5up)
UBC Department of Medicine Page 39 Annual Report 2007
Respiratory Medicine
Bai Clinical Trial Intermune Pharmaceuticals Inc. 890
A randomized, double-blind, placebo-controlled phase II study of the safety and efficacy of subcutaneous recombinant interferon-y1b (rlFN-y 1b) in patients with idiopathic pulmonary fibrosis
Respiratory Medicine
Bai Clinical Trial Topigen Pharmaceuticals Inc. 11,112
Protocol Topigen Asthma Study: A phase II, , randomised, double-blind, placebo-controlled, parallel-groups, multicentre study to evaluate and compare the safety, tolerability, and efficacy of two dosages of inhaled TPI ASMB (0.25 mg and 0.5 mg)
Respiratory Medicine
Carlsten Grant Vancouver Coastal Health Authority 75,000
Particle exposure health effects research facility
Respiratory Medicine
Carlsten Grant UBC Department of Medicine 20,000
Start-Up Funds from Respiratory Division
Respiratory Medicine
Cook Grant MSFHR: Institutional Infrastructure Support Program
100,000
In it for Life Mentored Clinician Scientist Award: Using location-based screening to improve tuberculosis control efforts in high-risk communities of the Vancouver Coastal Health Authority
Respiratory Medicine
Duronio Grant CIHR: Operating Grant MOP-74481 141,673
Mcl-1 as a regulator of cell cycle progression
Respiratory Medicine
Duronio Grant Heart and Stroke Foundation of British Columbia and Yukon - Research
70,482
Activation of macrophage growth and survival pathways by oxidized LDL
Respiratory Medicine
Duronio Grant CIHR/Strategic: Request for Applications (Full) MIF-79630
154,258
The mechanistic basis of post-lung transplantation bronchiolitis obliterans and therapeutic approaches
Respiratory Medicine
Duronio Grant MSFHR: Postdoctoral Trainee Fellowship ST-PDF 164(03-1)BM (Fellow: Germain, Marc)
9,750
Analysis of nuclear and cytoplasmic Mcl-1 protein complexes
Respiratory Medicine
Duronio Grant CIHR: Postdoctoral Fellowship MFE-78141 (Fellow; Scott, Alexander)
5,000
Research allowance: Characterizing apoptosis and survival pathways in tendon: the pathogenesis of overuse tendinopathy and its treatment with IGF-1
Respiratory Medicine
Duronio Grant CIHR: Postdoctoral Fellowship MFE-78141 (Fellow; Scott, Alexander)
50,000
Salary: Characterizing apoptosis and survival pathways in tendon: The pathogenesis of overuse tendinopathy and its treatment with IGF-I
Respiratory Medicine
Duronio Grant Canadian Cystic Fibrosis Foundation - Research Grants
5,000
The mechanistic basis of post-lung transplantation bronchiolitis obliterans and therapeutic approaches
Respiratory Medicine
Fitzgerald Grant AstraZeneca Canada Inc. 20,000
Asthma and Health Literacy in New Immigrant Communities in the Greater Vancouver Area (GVA): A Preliminary Proposal
Respiratory Medicine
Fitzgerald Agreement GlaxoSmithKline (Canada) Inc. 110,481
ECLIPSE: A Multicentre 3 Year Longitudinal Prospective Study to Identify Novel Endpoints and Compare These with Forced Expiratory Volume in 1 Second (FEV) for their ability to Measure and Predict COPD Severity and its progression Over Tim
UBC Department of Medicine Page 40 Annual Report 2007
Respiratory Medicine
Fitzgerald Agreement GlaxoSmithKline (Canada) Inc. - Asthma PRIISME Program
100,000
The Development of Asthma Education Programs Through a Novel Chronic Disease Management Model: PRIISM
Respiratory Medicine
Fitzgerald Agreement Novartis Pharmaceuticals Canada Inc.
3,000
CQAB149B2335S: A 26 Week Treatment, Multicenter, Randomized, Double-Blind, Double Dummy, Placebo-Controlled, Adaptive, Seamless, Parallel-Group Study to Assess the Efficacy, Safety and Tolerability of Two Doses of Indacaterol (selected fro,
Respiratory Medicine
Fitzgerald Agreement Boehringer Ingelheim (Canada) Ltd. 9,750
BI1744CL - 1222.6: Randomized, Double-Blind, Placebo-Controlled, Parallel Group study to Assess the Efficacy (Bronchodilation) and safety of 4 weeks of once daily treatment of orally inhaled BI 1744 CL (2ug, 5ug, 10ug, 20ug) delivered by Ri
Respiratory Medicine
Fitzgerald Agreement Topigen Pharmaceuticals Inc. 17,254
TPI ASM8-204: A Phase II, Randomized, Double-Blind, Placebo-Controlled, Parallel-Groups, Multicenter Study to Evaluate and Compare the Safety, Tolerability and the Efficacy of Two Dosages of Inhaled TPIASM8 (0.25mg vs 0.5mg) with Placebo i
Respiratory Medicine
Fitzgerald Grant MSFHR: Scholar Award 103,013
Bringing evidence to the patient
Respiratory Medicine
Fitzgerald Grant CIHR: Doctoral Research Awards CGD-80423 (Fellow: Moniruzzaman, A.K.M.
5,000
Research Allowance: Treatment of latent TP infection: measuring effectiveness among the contacts of TB cases
Respiratory Medicine
Fitzgerald Clinical Trial National Cancer Institute of Canada - Clinical Trials Group
6,000
IICT: A Phase III Randomized Study of Exemestane vs. Placebo in Postmenopausal Women at Increased Risk of Developing Breast Cancer
Respiratory Medicine
Fitzgerald Contract US Centers for Disease Control and Prevention
45,449
Task 13: Factors associated with acceptance of adherence to toxicity from treatment for Latent Tuberculosis Infection (TLTBI) and pilot study of TLBI effectiveness
Respiratory Medicine
Fitzgerald Clinical Trial CIHR: Randomized Controlled Trials 13,400
IICT: Asthma in Obese Subjects - Diagnostic & Therapeutic Strategies
Respiratory Medicine
Fitzgerald Agreement Hoffmann-La Roche Ltd. (Canada) 6,000
NA20030A: Roche Integrin Antagonist Follow-up for Undetected PML
Respiratory Medicine
Fitzgerald Clinical Trial GlaxoSmithKline (Canada) Inc. 13,552
SCO100250: A Randomized, Double-Blind, Parallel Group, 52-week Study to Compare the Effect of the Fluticasone Propionate/Salmeterol DISKUS Combination Product 250/50mcg BID with Salmeterol DISKUS 50mcg BID on the Annual Rate of Moderate/..
Respiratory Medicine
Fitzgerald Grant CIHR Team Grant Program - Letter of Intent
10,000
CIHR Team in Respiratory Clinical Research
Respiratory Medicine
Fitzgerald Agreement Wyeth Canada 28,507
Protocol 3174K1-200-Ca: The Effects of IMA-638 on Allergen-Induced Airway Responses and Airway Inflammation in Subjects with Mild Atopic Asthma
UBC Department of Medicine Page 41 Annual Report 2007
Respiratory Medicine
Fitzgerald Agreement Novartis Pharmaceuticals Canada Inc.
625
CIGE025ACA02: XCEED Xolair Canadian Evaluation of Effectiveness in Asthmatic Disease: A Post-registration Evaluation of Long Term Xolair (omalizumab) Therapy on Patient-relevant Outcomes, Medical Resource Use and Asthma Medication Requirements
Respiratory Medicine
Fitzgerald Agreement Skye Pharma 27,294
SKY2028-3-002 A Double-blind, Active-controlled, Parallel-group, Stratified, Multicenter, 12-week Study Comparing The Safety and Efficacy of Fluticasone and Formoterol combination (Flutiform 100/10ug twice daily) in a Single Inhaler - SkyePhn
Respiratory Medicine
Fitzgerald Agreement Genentech Inc. 5,808
Q4160g A Phase II, Multicenter, Randomized, Double-blind, Parallel-group, Placebo-controlled Study to Evaluate the Efficacy and Safety of Lyphilized and Aged Liquid Omalizumab in the Prevention of Allergen Induced Airway Obstruction in Adults…
Respiratory Medicine
Fitzgerald Grant CIHR/BC Lung Assn: Investigator 10,238
Bringing evidence to the patient
Respiratory Medicine
Fitzgerald Agreement Novartis Pharmaceuticals Canada Inc.
4,000
CIGE025A2433: International Registry of Real-World Outcomes for Asthma Patients Treated with Xolair
Respiratory Medicine
Fleetham Grant CIHR/ Canadian Lung Association Postdoctoral Fellowship BCF-82235 (Fellow: Mulgrew, Alan)
2,500
Research Allowance: The inflammatory and Cardiovascular Phenotype of Obstructive Sleep Apnea Hypopnea Syndrome
Respiratory Medicine
Fleetham Grant MSFHR: Research Unit Infrastructure Support Program
139,000
Respiratory Sleep Disorders Research Unit
Respiratory Medicine
Fleetham Grant VCHA: Venture Grants 30,000
Dynamic 3-Dimensional Upper Airway Modeling of the Effect of Oral Appliances for the Treatment Obstructive Sleep Apnea/Hypopnea
Respiratory Medicine
Fleetham Grant CIHR/ Canadian Lung Association Postdoctoral Fellowship BCF-82235 (Fellow: Mulgrew, Alan)
25,000
Stipend: The inflammatory and Cardiovascular Phenotype of Obstructive Sleep Apnea Hypopnea Syndrome
Respiratory Medicine
Fleetham Grant British Columbia Lung Association Fellowship (Fellow: Mulgrew, Alan)
27,500
The inflammatory and Cardiovascular Phenotype of Obstructive Sleep Apnea Hypopnea Syndrome
Respiratory Medicine
Khalil Grant British Columbia Lung Association 22,500
Alveolar Epithelial Cell Derived TGF-B1 Regulation of Fibroblast Function
Respiratory Medicine
Khalil Contract Pacific Therapeutics Ltd. 145,000
CRA: Therapeutic Applications of CD36 9-110 Peptide in Progressive and Lethal Diseases
Respiratory Medicine
Khalil Agreement InterMune Inc. 34,795
PIPF-004: A Randomized, Double-Blind, Placebo-Controlled, Phase 3, Three Arm Study of the Safety and Efficacy of Pirfenidone in Patients with Idiopathic Pulmonary Fibrosis
Respiratory Medicine
Knight Grant CIHR Operating Grant 82,152
Regulation of gp130 signaling by STAT-3 in the pathogenesis of pulmonary fibrosis
UBC Department of Medicine Page 42 Annual Report 2007
Respiratory Medicine
Knight Grant Canada Fdn for Innovation - Cdn matching funds
15,075
Mechanisms of airway disease
Respiratory Medicine
Knight Grant Canada Fdn for Innovation - US matching funds
6,982
Mechanisms of airway disease
Respiratory Medicine
Knight Agreement UBC Industry Liaison Office 10,000
Novel Method for Treatment of Asthma
Respiratory Medicine
Knight Grant Sepracor Inc. 45,000
The role of epithelial stem/progenitor cells in epithelial repair
Respiratory Medicine
Knight Clinical Trial Sepracor Inc. 24,005
The role of (R) and (S) enantomers of albuterol in mucosal injury and repair in pediatric asthma
Respiratory Medicine
Lam Clinical Trial Asthmatx Inc 10,867
Feasibility Study of the Broncus Alair System for the treatment of asthma
Respiratory Medicine
Levy Clinical Trial Actelion Pharmaceuticals Canada Inc.
1,110
A double-blind, randomized, placebo-controlled, multicenter study to assess the efficacy, safety and tolerability of bosentan in patients with idiopathic pulmonary fibrosis
Respiratory Medicine
Levy Clinical Trial GlaxoSmithKline (Canada) Inc. 62,835
A Multicentre 3 Year Longitudinal Prospective Study to Identify Novel Endpoints and Compare These with Forced Expiratory Volume in 1 Second (FEV1) for Their Ability to Measure and Predict COPD Severity and its Progression Over SCO104960
Respiratory Medicine
Levy Grant Universite Laval 16,193
IC077202 Effects of home-based versus hospital-based outpatient pulmonary rehabilitation ion patients with COPD: A multicenter, randomize clinical trial
Respiratory Medicine
Levy Clinical Trial Encysive L.P. 10,175
Protocol FPH03 STRIDE III: Long-Term Open-Label Study to Evaluate the Safety of Sitaxsentan Sodium Treatment in Patients with Pulmonary Arterial Hypertension
Respiratory Medicine
Levy Agreement GlaxoSmithKline (Canada) Inc. 120,000
ECLIPSE: A multicentre, 3-year study to compare novel COPD biomarker endpoints with FEV1 in patients with COPD and control subjects
Respiratory Medicine
Man Grant CIHR - Rx & D: Research Program COP-76849
51,700
Systemic biomarkers in COPD: Can they predict future cardiovascular and cancer morbidity in COPD?
Respiratory Medicine
McWilliams Grant VCHRI 20,000
Equipment Fund
Respiratory Medicine
McWilliams Grant Vancouver Coastal Health Authority 50,000
MCS: Comparison of EBUS-TBNA and Surgical Lymph Node Sampling: A Feasibility Study
Respiratory Medicine
McWilliams Grant VGH and UBC Hospital Foundation 80,000
Equipment fund
Respiratory Medicine
McWilliams Grant UBC Faculty of Medicine 20,000
Start-up funds: MCS: Comparison of EBUS-TBNA and Surgical Lymph Node Sampling: A Feasibility Study
UBC Department of Medicine Page 43 Annual Report 2007
Respiratory Medicine
Ostrow Clinical Trial Lilly ICOS 28,772
Protocols LVGX and LVGY: A Randomized Double-Blind, Study to Evaluate the Long-Term Safety and Efficacy of the Phosphodiesterase Type 5 (PDE5) Inhibitor Tadalafil in the Treatment of Patients with Pulmonary Arterial Hypertension
Respiratory Medicine
Ostrow Agreement United Therapeutics Corp. 16,762
TDE-PH-301: A 16 week, International, Multicenter, Double-Blind, Randomized, Placebo Controlled Comparison of the Efficacy and Safety of Oral UT-15C SR Tablets in Combination with an Ednothelin Receptor antagonist and/or a Phosphodiestera
Respiratory Medicine
Ostrow Agreement United Therapeutics Corp. 82
TDE-PH-304: An Open-Label Extension Trial of UT015C in Subjects with Pulmonary Arterial Hypertension
Respiratory Medicine
Pare Contract National Institutes of Health 1,255
Smoke Induced Airway Injury in COPD
Respiratory Medicine
Pare Grant CIHR Research Development Grant 13,377
The use of high resolution computed tomographic scanning in the phenotyping of COPD. Validation and application in a clinical trial
Respiratory Medicine
Pare Grant MSFHR Research Unit Infrastructure Support Program
246,125
Genetic-environment interactions lead to the phenotypic expression of inflammatory heart, lung and blood vessel diseases
Respiratory Medicine
Pare Grant CIHR Operating Grant 110,850
Genetics and Epigenetic Determinants of Asthmatic Epithelia Cell Phenotype
Respiratory Medicine
Pare Grant Merck Frosst Canada Ltd. 84,115
GEODE/ Alveolar Macrophage Gene Expression in COPD; Gene Expression in Obstructive Lung Disease and Emphysema (GEODE)
Respiratory Medicine
Pare Grant CIHR Operating Grant 121,360
Human airway smooth muscle function and bronchial hyper responsiveness: Length adaptation in airway smooth muscle
Respiratory Medicine
Pare Grant MSFHR Senior Graduate Studentship Award
2,500
Genetic and epigenetic studies of innate immunity related genes in the development of asthma in childhood: the role of airway epithelial cells
Respiratory Medicine
Pare Grant British Columbia Lung Association - Investigator
32,500
BC Lung Association/St. Paul's Hospital Investigator Award: Dr. Don Sin
Respiratory Medicine
Pare Grant Heart and Stroke Foundation of Canada - Strategic Training Initiatives
34,065
IMPACT: Integrated and mentored pulmonary and cardiovascular training
Respiratory Medicine
Pare Grant Canadian Institutes of Health Research (CIHR): Postdoctoral Fellowship (Fellow: Daley, Denise)
5,000
Investigation of epistasis and genetic susceptibility to hypertension in men and women
Respiratory Medicine
Pare Grant CIHR: Strategic Training Program Grant - Institute of Aging
273,413
IMPACT: Integrated and mentored pulmonary and cardiovascular training
Respiratory Medicine
Pare Grant CIHR: Physical Medicine Research Foundation/CIHR Fellowship (Fellow: Camp, Patricia)
5,000
Gender differences in chronic obstructive pulmonary disease
UBC Department of Medicine Page 44 Annual Report 2007
Respiratory Medicine
Pare Grant Canadian Institutes of Health Research (CIHR): Postdoctoral Fellowship (Fellow: Daley, Denise)
40,000
Investigation of epistasis and genetic susceptibility to hypertension in men and women
Respiratory Medicine
Pare Clinical Trial GlaxoSmithKline (Canada) Inc. 34,094
CRA: Develop and standardize accurate measurements of emphysema and airway wall dimensions in human lungs
Respiratory Medicine
Road Agreement Synapse Biomedical Inc. 2,978
Electrical Activation of the Diaphragm for Ventilatory Assist (Multi-Center Pivotal Study of NeuRx RA/4 Ventilatory Assist Device)
Respiratory Medicine
Road Agreement AstraZeneca AB 10,255
D5892C00015: A 12 week, double-blind, randomised, parallel group, multi-centre, study to evaluate efficacy and safety of budesonide/formoterol (Symbicort Turbuhaler) 320/9 ug one inhalation twice daily on top of tiotropium (Spiriva) 18ug on
Respiratory Medicine
Road Clinical Trial Spiration Inc. 115,981
CPR-0003: Study to Find Out If a New Medical Device Called the Intra-Bronchial Valve (IBV) is Safe and Effective to Use in Subjects With Severe Emphysema
Respiratory Medicine
Road Grant Rick Hansen Man In Motion Foundation
4,480
Electrical Activation of the Diaphragm for Ventilatory Assist Clinical Study
Respiratory Medicine
Road Agreement Nycomed Canada Inc. 39,598
BY217/M2-127 "THE EOS STUDY" -- Effect of Roflumilast in COPD Patients treated with Salmeterol: A 24-week, Double-blind Study with 500 ug Roflumilast Once Daily vs. Placebo
Respiratory Medicine
Sandford Grant Canadian Cystic Fibrosis Foundation - Research Grants
94,530
Genetic modifiers of disease severity in cystic fibrosis
Respiratory Medicine
Sandford Grant Canadian Lung Association - CLA/MRC Fellowship
45,000
Genetic polymorphisms in costimulatory molecules and the development of asthma
Respiratory Medicine
Sandford Grant Canada Research Chair Tier II (CIHR)
100,000
Canada Research Chair in genetics of respiratory disease for Dr. Andrew Sandford
Respiratory Medicine
Sandford Grant MSFHR Scholar Award 80,000
Genetic modifiers of pulmonary disease severity in cystic fibrosis
Respiratory Medicine
Sin Grant MSFHR Establishment Grant 37,500
Why are women at increased risk of chronic obstructive pulmonary disease and lung cancer? Is inflammation the missing link?
Respiratory Medicine
Sin Grant AstraZeneca Canada Inc. 108,075
Molecular Links Between Lung and Systemic Inflammation in COPD
Respiratory Medicine
Sin Grant CIHR: University-Industry Program - Operating Grants
96,228
Longitudinal Study of Disease Progression in COPD
Respiratory Medicine
Sin Grant Merck Frosst Canada Ltd. 35,000
Biomarker
Respiratory Medicine
Sin Grant Canadian Institutes of Health Research (CIHR)
111,553
Why are women at increased risk of chronic obstructive pulmonary disease and lung cancer? is inflammation the missing link?
UBC Department of Medicine Page 45 Annual Report 2007
Respiratory Medicine
Sin Grant MSFHR: Team Start-up Infrastructure Award
75,000
COPD and inflammation team (CAIT)
Respiratory Medicine
Sin Grant Canadian Lung Association: Scholarships in Respiratory Health Type I and II
7,500
A pilot study of barriers participating pulmonary rehabilitation programs
Respiratory Medicine
Sin Grant CIHR/IMHA Interdisciplinary Capacity Enhancement (ICE) Team
288,126
Interdisciplinary Capacity Enhancement: Bridging Excellence in Respiratory Disease and Gender Studies (ICEBERGS)
Respiratory Medicine
Sin Clinical Trial GlaxoSmithKline (Canada) Inc. 5,353
Protocol AIM (ADC105931): A Randomized, Double-Blind, Parallel-Group, 14-Week Study to Evaluate the Anti-Inflammatory Effect of Fluticasone Propionate/ Salmeterol DISKUS 250/50mcg BID Compared to Salmeterol DISKUS 50mcg BID in Subjects With…
Respiratory Medicine
Sin Grant CIHR Team Grant Program - Letter of Intent
10,000
Chronic Obstructive Pulmonary Disease (COPD): From Molecules to Population
Respiratory Medicine
Sin Grant MSFHR: Matching Establishment Grant
75,000
Why are women at increased risk of chronic obtrusive pulmonary disease and lung cancer? Is inflammation the missing link?
Respiratory Medicine
Sin Grant CIHR: TUTOR-PHC Fellowship (Fellow: Guo, Su-Er)
5,000
A pilot study of barriers to participating pulmonary rehabilitation programs
Respiratory Medicine
Sin Clinical Trial AstraZeneca AB 4,000
Protocol D5892C00015 (CLIMB): A 12-WEEK, DOUBLE-BLIND, RANDOMISED, PARALLEL GROUP, MULTI-CENTRE STUDY TO EVALUATE EFFICACY AND SAFETY OF BUDESONIDE/ FORMOTEROL (SYMBICORT(R) TURBUHALER(R)) 320/9 ug ONE INHALATION TWICE DAILY ON TOP OF TIOT
Respiratory Medicine
Sin Grant MSFHR Senior Scholar Award 15,000
Why are women at increased risk of chronic obstructive pulmonary disease and lung cancer? Is inflammation the missing link?
Respiratory Medicine
Sin Grant Canada Research Chair Tier II (CIHR)
100,000
Canada Research Chair in Chronic Obstructive Pulmonary Disease for Dr. Don Sin
Respiratory Medicine
Sin Clinical Trial St. Joseph's Health System 155,205
IICT: Can Advair and Flovent reduce systemic inflammation related to COPD? A multi-center randomized controlled Trial.
Respiratory Medicine
Swiston Grant UBC Department of Medicine 20,000
Risk factors for hospital readmission in patients with COPD
Respiratory Medicine
Swiston Grant VCHRI: In it for Life Investigator Awards
50,000
Risk factors for hospital readmission in patients with COPD
Respiratory Medicine
Tebbutt Grant Allergy, Genes and Environment Network (AllerGen) - Networks of Centres of Excellence
36,000
AllerGen Animations
Respiratory Medicine
Tebbutt Grant National Sanitarium Association 80,000
Real-Time Clinical Genomics In Pulmonary Medicine
Respiratory Medicine
Tebbutt Grant Allergy, Genes and Environment Network (AllerGen) - Networks of Centres of Excellence
61,940
Knowledge, discovery, management and transfer - AllerGen Theme I Web Resource
Respiratory Medicine
Tebbutt Grant Allergy, Genes and Environment Network (AllerGen) - Networks of Centres of Excellence
55,020
Mini-CHILD Genetics
Respiratory Medicine
Tebbutt Grant Allergy, Genes and Environment Network (AllerGen) - Networks of Centres of Excellence
70,000
Development of a Microarray Genotyping Chip for Clinical Trials
Respiratory Medicine
Van Eeden Clinical Trial National Institutes of Health 59,420
IICT: Diesel Exhaust and Atherosclerotic Plaque Stability
Respiratory Medicine
Van Eeden Grant MSFHR: Senior Graduate Studentship Award
4,417
Particular matter air pollution induces vascular endothelial dysfunction
Respiratory Medicine
Van Eeden Agreement GlaxoSmithKline (Canada) Inc. 50,000
PRIISME PROGRAM
Respiratory Medicine
Van Eeden Grant British Columbia Lung Association 20,000
Particulate Matter Air Pollutants and Chronic Obstructive Pulmonary Disease
Respiratory Medicine
Van Eeden Grant MSFHR: Senior Scholar Award CI-SSH-080(05-1) CLIN
100,000
Lung inflammation induced cardiovascular disease
Respiratory Medicine
Ward Grant Agriculture Canada 2,000
Canadian Agricultural Injury Surveillance Program
Respiratory Medicine
Wilcox Clinical Trial InterMune Inc. 48,840
A Randomized, Double-blind, Placebo-controlled, Phase III Three-arm Study of the Safety and Efficacy of Pirfenidone in Patients with Idiopathic Pulmonary Fibrosis
Respiratory Medicine
Wilcox Grant Ottawa Health Research Institute 1,860
IICT: Evaluation of a Decision Aid for Adult Cystic Fibrosis patients Considering Bilateral Lung Transplantation
Respiratory Medicine
Wilcox Clinical Trial Intermune Pharmaceuticals Inc. 20,616
A randomized, double-blind, placebo-controlled, phase III study of the safety and efficacy of Interferon Gamma-1b in patients with idiopathic pulmonary fibrosis -- the INSPIRE Trial: INternational study of Survival outcomes in IPF with InteRfEron
Respiratory Medicine
Wilcox Clinical Trial Boehringer Ingelheim (Canada) Ltd. 28,172
205.372-Spiriva Respimat(TM) Study: A Randomised, Double-Blind, Placebo-Controlled, Parallel-Group Study to Assess Long Term (one-year) Efficacy and Safety of Tiotropium Inhalation Solution 5ug (2 puffs of 2.5ug) Delivered by the Respimat
Respiratory Medicine
Wilcox Clinical Trial Perceptronix Medical Inc. 3,000
Protocol FLUTE: Evaluation of "Lung Flute" TM for Sputum Collection
Respiratory Medicine
Wilcox Clinical Trial Pharmaxis Ltd. 3,576
DPM-CF-202: A Phase IIA, Randomised, Open-label, Dose-response Study to Determine the Optimum Dose of Dry Powder Mannitol Required to Generate Clinical Improvement in Patients with Cystic Fibrosis
Respiratory Medicine
Wilcox Clinical Trial Perceptronix Medical Inc. 20,206
Spectral Imaging of Early Lung Cancers and Pre-Cancerous Lesions
Respiratory Medicine
Wilcox Clinical Trial Corus Pharma Inc. 7,750
A Phase 3, Double-Blind, Multicenter, Multinational, Randomized, Placebo-Controlled Trial Evaluating Aztreonam Lysinate for Inhalation in Cystic Fibrosis Patients with P. Aeruginosa (AIR-CF1)
Respiratory Medicine
Wilcox Clinical Trial Actelion Pharmaceuticals Canada Inc.
28,010
Protocol AC-052-321 BUILD 3: Effects of Bosentan on Morbidity and Mortality in Patients With Idiopathic Pulmonary Fibrosis - A Multicenter, Double-Blind, Randomized, Placebo-Controlled, Parallel Group, Event-Driven, Group Sequential, Phase
Rheumatology Choi Grant Canadian Institutes of Health
Research (CIHR)
32,894 Role of statins in prevention and management of rheumatoid arthritis
Rheumatology Cibere Grant CIHR Clinician Scientist - Phase II MC2-69188
62,488
Development of a Model for the MRI Progression of Knee Osteoarthritis
Rheumatology Esdaile Grant CIHR: Request for Proposal/Application
150,000
Tooling Up for OA: Measuring What Matters
Rheumatology Esdaile Grant Canadian Arthritis Network (CAN) - Networks of Centres of Excellence (NCE)
150,000
Tooling Up for OA: Measuring What Matters
Rheumatology Esdaile Grant CIHR / Rx&D Research Program - Postdoctoral Fellowship XWY-82340 Fellow: Avina-Zubieta, Juan Antonio)
10,000
Research Allowance: Cardiovascular morbidity and mortality associated with the use of corticosteroids in patients with rheumatoid arthritis. A population based study
Rheumatology Lacaille Grant Arthritis Society Investigator Award 80,500
Evaluating care for rheumatoid arthritis and preventing work disability in inflammatory arthritis
Rheumatology Lacaille Grant Disabilities Health Research Network (DHRN)
7,923
Carrier Sekani First Nations Band Telerehabilitation Project - Research Planning Workshop
TOTAL:
40,723,460