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IZBORNOM VEĆU UNIVERZITETA U BEOGRADU – BIOLOŠKOG FAKULTETA

Na VIII redovnoj sednici Izbornog veća Univerziteta u Beogradu – Biološkog fakulteta, održanoj 09.06.2017. godine, određeni smo u Komisiju za pripremu izveštaja o kandidatima prijavljenim na konkurs za jednog redovnog profesora za užu naučnu oblast Biohemija i molekularna biologija na Univerzitetu u Beogradu – Biološkom fakultetu na Institutu za fiziologiju i biohemiju, Katedri za biohemiju i molekularnu biologiju. Na konkurs objavljen u listu "Poslovi" 21.06.2017. godine, broj 731, prijavila su se dva kandidata: dr Dušanka Savić-Pavićević, vanredni profesor Univerziteta u Beogradu – Biološkog fakulteta i dr Životije Radisavljević, specijalista interne medicine, onkologije i hematologije.

Na osnovu analize priložene dokumentacije kandidata dr Životija Radisavljevića rođenog 01.05.1954. godine Komisija konstatuje da je kandidat dana 02. 07. 1986. godine stekao naučni stepen doktora medicinskih nauka na Univerzitetu u Beogradu – Medicinskom fakultetu, kao i da ne poseduje iskustvo u pedagoškom radu sa studentima. Kako je uslovima konkursa i Pravilnikom o minimalnim uslovima za sticanje zvanja nastavnika na Univerzitetu u Beogradu (član 13, tabela A1) kao opšti uslov za izbor u zvanje nastavnika propisan doktorat nauka iz naučne oblasti za koju se kandidat bira, a to je Biologija, i kako isti Pravilnik u članu 4 propisuje nastavni rad kao obavezan uslov za izbor u zvanje nastavnika, Komisija je konstatovala da kandidat dr Životije Radisavljević ne ispunjava uslove da bude izabran u zvanje redovnog profesora za užu naučnu oblast Biohemija i molekularna biologija, te u daljem postupku nije ovog kandidata uzela u razmatranje.

Na osnovu analize priložene dokumentacije kandidata dr Dušanke Savić-Pavićević, Izbornom veću Univerziteta u Beogradu – Biološkom fakultetu podnosimo sledeći

I Z V E Š T A J

1. BIOGRAFSKI PODACI

Dušanka Savić-Pavićević rođena je 19.01.1972. godine u Kotoru. Diplomirala je na Univerzitetu u Beogradu – Biološkom fakultetu, na studijskoj grupi Molekularna biologija i fiziologija 1998. godine sa prosečnom ocenom 9,81 i diplomskim radom pod naslovom „Populaciona analiza MJD1/SCA3 gena odgovornog za Machado-Josephovu bolest (spinocerebelarnu ataksiju tip 3)“. Poslediplomske studije na smeru Molekularna biologija i biohemija na Univerzitetu u Beogradu – Biološkom fakultetu završila je 2000. godine odbranom magistarskog rada pod naslovom „Molekularna genetika miotonične distrofije: intergeneracijska i somatska nestabilnost broja CTG ponovaka u MtPK genu“. Doktorsku tezu pod naslovom „Komparativna analiza HD gena kod vrsta različite evolucione starosti“ odbranila je 2004. godine na istom fakultetu. Njen mentor bila je prof. Stanka Romac.

Od 1998. do 2000. godine Dušanka Savić-Pavićević bila je stipendista Ministarstva za nauku i tehnologiju Republike Srbije. Od 2000. godine zaposlena je na Univerzitetu u Beogradu – Biološkom fakultetu, na Katedri za biohemiju i molekularnu biologiju. Kao asistent pripravnik za predmet Molekularna biologija eukariota zaposlena je 2000. godine, a 2001. godine izabrana je u zvanje asistent. Zvanje docent za užu naučnu oblast Molekularna biologija stekla je 2005. godine, a 2010. godine unapređena je u vanrednog profesora za užu naučnu oblast Biohemija i molekularna biologija. U isto zvanje reizbarna je u oktobru 2015. godine.

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Od 2008. godine Dušanka Savić-Pavićević bila je pomoćnik rukovodioca Centra za humanu molekularnu genetiku Biološkog fakulteta za oblast medicinske dijagnostike naslednih bolesti i utvrđivanja očinstva, a 2016. godine imenovana je za v.d. rukovodioca Centra. Sudski je veštak iz oblasti Biologija za užu specijalnost DNK veštačenja, forenzička genetika.

2. NASTAVNI RAD

2.1. Kvantitativan prikaz postignutih rezultata nastavnog rada

Vrsta rezultata Vrednost Broj Poeni Broj PoeniPosle izbora Ukupno

Osnovne nastavne aktivnostiObjavljen udžbenik 20 – 0 1 20Mentorstvo – odbranjena doktorska disertacija 12 1 12 1 12Mentor sa fakulteta – odbranjena doktorska disertacija 6 11 66 15 90Mentor sa fakulteta – odbranjena magistarska teza 4 – 0 1 4Mentor sa fakulteta – odbranjen specijalistički rad 3 1 3 1 3Mentorstvo – odbranjen diplomski ili master rad 4 11 44 12 48Mentor sa fakulteta – odbranjen diplomski ili master rad 2 24 48 32 64Učešće u komisiji za odbranu doktorske disertacije 4 12 48 15 60Učešće u komisiji za odbranu magistarskog rada 3 – 0 3 9Učešće u komisiji za odbranu diplomskog ili master rada 1 19 19 25 25Držanje nastave na kursu – u potpunosti pripremljen nastavni program 6 3 18 6 36

Držanje nastave na kursu – pripremljena dopuna nastavnog programa 4 1 4 2 8

Učešće u realizaciji praktične nastave na kursu po školskoj godini 1 0 0 16 16Ukupno 262 395

Ostale nastavne aktivnostiDržanje nastave za stručno usavršavanje nastavnika 1 5 5 5 5Učešće u pedagoškom radu sa učenicima osnovnih i srednjih škola 1 1 1 1 1

Recenzija udžbenika kategorije M90 3 2 6 2 6Recenzija ostalih publikacija kategorije M90 1 1 1 1 1Članstvo u organizacionim odborima međunarodnih/nacionalnih/ stručnih skupova 2/1/0.5 4 3.5 4 3.5

Ukupno 16.5 16,5Ukupno osnovne i ostale nastavne aktivnosti 278.5 411.5

Prema Pravilniku o kriterijumima za pokretanje postupka za sticanje nastavničkih zvanja na Univerzitetu u Beogradu – Biološkom fakultetu D. Savić-Pavićević je iz nastavnih aktivnosti posle izbora u zvanje vanredni profesor ostvarila ukupno 278,5 bodova (za redovnog profesora potrebno je ukupno 66 bodova).

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2.2. Osnovne nastavne aktivnosti

Objavljen udžbenikNakon izbora 0

Ukupno 1x20=20***1

1. Savić Pavićević D , Matić G. Molekularna biologija 1. Beograd: NNK internacional; 2011. ISBN 978-86-6157-001-8.

Mentorstvo – odbranjena doktorska disertacijaNakon izbora 1x12=12

Ukupno 1x12=12

1. Jelena Karanović. Varijante u genima za editovanje RNK, serotoninski receptor 2C i triptofan-hidroksilazu 2 kao faktori rizika za pokušaj samoubistva kod psihijatrijskih bolesnika. Doktorska disertacija. Biološki fakultet, Univerzitet u Beogradu. 2017.Komisija: dr Dušanka Savić-Pavićević (mentor), dr Goran Brajušković, dr Maja Ivković, dr Vladimir Jovanović.

Mentor sa fakulteta – odbranjena doktorska disertacijaNakon izbora 11x6=66

Ukupno 15x6=90

1. Branislava Gemović. Bioinformatička analiza proteina uključenih u patogenezu mijeloidnih maligniteta. Doktorska disertacija. Biološki fakultet, Univerzitet u Beogradu. 2015.Komisija: dr Nevena Veljković (mentor), dr Dušanka Savić-Pavićević (mentor), dr Dragomir Marisavljević, dr Goran Brajušković, dr Katarina Nikolić.

2. Branka Kolundžija. Ispitivanje mehanizama antitumorskog delovanja derivata antrahinona in vitro. Doktorska disertacija. Biološki fakultet, Univerzitet u Beogradu. 2014.Komisija: dr Tatjana Stanojković (mentor), dr Dušanka Savić-Pavićević (mentor), dr Milan Joksović.

3. Iva Pruner. Funkcionalna analiza genske varijante C20068T u 3 kraju gena za protrombin čoveka i njena uloga u patogenezi trombofilije. Doktorska disertacija. Biološki fakultet, Univerzitet u Beogradu. 2014.Komisija: dr Valentina Đorđević (mentor), dr Dušanka Savić-Pavićević (mentor), dr Dragica Radojković, dr Mirjana Kovač, dr Branko Tomić.

4. Milena Milivojević. Uloga Sonic hedgehog signalnog puta u regulaciji ekspresije SOX18 gena u HeLa ćelijama, kao model sistemu karcinoma grlića materice. Doktorska disertacija. Biološki fakultet, Univerzitet u Beogradu. 2014.Komisija: dr Isidora Petrović (mentor), dr Dušanka Savić-Pavićević (mentor), dr Milena Stevanović.

5. Ivana Matić. In vitro ispitivanje antitumorske aktivnosti ekstrakata endemične biljne vrste Helichrysum zivojinii Černjavski et Soška. Doktorska disertacija. Biološki fakultet, Univerzitet u Beogradu. 2013.Komisija: dr Zorica Juranić (mentor), dr Dušanka Savić-Pavićević (mentor), dr Vlatka Vajs, dr Ivana Aljančić, dr Katarina Šavikin.

1Razdvaja aktivnosti/bibliografske jedinice pre i posle izbora u zvanje vanredni profesor u oktobru 2010. godine.

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6. Milica Nešić. Varijabilnost genoma humanog virusa Parvovirus B19 (Parvoviridae, Erythrovirus). Doktorska disertacija. Biološki fakultet, Univerzitet u Beogradu. 2013.Komisija: dr Gorana Stamenković (mentor), dr Dušanka Savić-Pavićević (mentor), dr Aleksandra Knežević.

7. Ljiljana Stojković. Uloga polimorfizama i ekspresije gena za hemokine CX3C ligand 1 i CXC ligand 16 i njihove receptore u nastanku i progresiji multiple skleroze u Srbiji. Doktorska disertacija. Biološki fakultet, Univerzitet u Beogradu. 2013.Komisija: dr Maja Živković (mentor), dr Dušanka Savić-Pavićević (mentor), dr Evica Dinčić.

8. Vesna Spasovski. Molekularni mehanizmi patogeneze mijelo-proliferativnih neoplazaija: poremaćaj ekspresije gena uključenih u proliferaciju i apoptozu. Doktorska disertacija. Biološki fakultet, Univerzitet u Beogradu. 2012.Komisija: dr Sonja Pavlović (mentor), dr Dušanka Savić-Pavićević (mentor), dr Gordana Nikčević.

9. Teodora Karan-Đurašević. Molekularna osnova hronične limfocitne leukemije: korelacija između mutacionog statusa teških lanaca imunoglobulina i ekspresije apoptotskih gena. Doktorska disertacija. Biološki fakultet, Univerzitet u Beogradu. 2012.Komisija: dr Sonja Pavlović (mentor), dr Dušanka Savić-Pavićević (mentor), dr Nataša Tošić.

10. Marija Vujanić. Molekularna detekcija i genotipizacija sojeva parazita Toxoplasma gondii izolovanih u Srbiji. Doktorska disertacija. Biološki fakultet, Univerzitet u Beogradu. 2012.Komisija: dr Vladimir Ivović (mentor), dr Dušanka Savić-Pavićević (mentor), dr Olgica Đurković Đaković.

11. Milena Radmilović. Varijante u genima-modifikatorima β-talasemijskih sindroma kao regulatori genske ekspresije i populaciono-genetički markeri. Doktorska disertacija. Biološki fakultet, Univerzitet u Beogradu. 2011.Komisija: dr Sonja Pavlović (mentor), dr Dušanka Savić-Pavićević (mentor), dr Maja Stojiljković Petrović, dr Gordana Nikčević.

***12. Jelena Popović. Transkripciona regulacija ekspresije humanog SOX14 gena.

Doktorska disertacija. Biološki fakultet, Univerzitet u Beogradu. 2010.Komisija: dr Milena Stevanović (mentor), dr Dušanka Savić-Pavićević (mentor), dr Svetlana Radović.

13. Nataša Tošić. Interakcija genetičkih markera proliferacije, diferencijacije i apoptoze kod akutnih leukamija. Doktorska disertacija. Biološki fakultet, Univerzitet u Beogradu. 2010.Komisija: dr Sonja Pavlović (mentor), dr Dušanka Savić-Pavićević (mentor), dr Milena Kataranovski, dr Milica Čolović.

14. mr Tatjana Stanojković. In vitro ispitivanja antiproliferativnog dejstva novih kompleksa Zn (II) sa heterocikličnim tiosemikarbazonima. Doktorska disertacija. Biološki fakultet, Univerzitet u Beogradu. 2010.Komisija: dr Zorica Juranić (mentor), dr Dušanka Savić-Pavićević (mentor), dr Stanka Romac, dr Zoran Kljajić.

15. mr Jelena Urošević. Proučavanje uloge B-Raf proteina u kanceru korišćenjem životinjskih tumor modela. Doktorska disertacija. Biološki fakultet, Univerzitet u Beogradu. 2009.

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Komisija: dr Sonja Pavlović (mentor), dr Dušanka Savić-Pavićević (mentor), dr Svetlana Radović, dr Mariano Barbacid Montalban.

Mentor sa fakulteta – odbranjena magistarska tezaNakon izbora 0

Ukupno 1x4=4***

1. Ojdanić Marijana. Polimorfizmi u β-globinskim lokusu kao markeri za poreklo i distribuciju β-talasemijskih mutacija u Srbiji i Crnoj Gori. Magistarski rad. Biološki fakultet, Univerzitet u Beogradu. 2005.Komisija: dr Sonja Pavlović (mentor), dr Dušanka Savić-Pavićević (mentor), dr Marina Stamenković Radak.

Mentor sa fakulteta – odbranjen specijalistički radNakon izbora 1x3=3

Ukupno 1x3=3

1. Amira Fazlagić. Farmakogenomski markeri kao prediktori efikasnosti leka metformina u populaciji Srbije. Specijalistički rad. Biološki fakultet, Univerzitet u Beogradu. 2016.Komisija: dr Dušanka Savić-Pavićević (mentor), dr Sonja Pavlović, dr Sofija Pavković-Lučić.

Mentorstvo – odbranjen master ili diplomski radNakon izbora 11x4=44

Ukupno 12x4=48

1. Srđan Maširević. Procena starosti mutacije povezane sa miotoničnom distrofijom tip 2 u evropskim populacijama. Master rad. Biološki fakultet, Univerzitet u Beogradu. 2016.Komisija: dr Dušanka Savić-Pavićević (mentor), dr Goran Brajušković, dr Vladimir Jovanović, Miloš Brkušanin.

2. Milicа Vunjak. Ispitivanje interakcija proteina uključenih u transkripciju prekursora piRNA kod Drosophila melanogaster. Master rad. Biološki fakultet, Univerzitet u Beogradu. 2016.Komisija: dr Dušanka Savić-Pavićević (mentor), dr Goran Brajušković.

3. Vlado Kovčić. Analiza haplotipova kod bolesnika sa miotoničnom distrofijom tipa 2 iz Srbije. 2015.Komisija: dr Dušanka Savić-Pavićević (mentor), dr Goran Brajušković, Jovan Pešović.

4. Miloš Mandić. Uspostavljanje metode za analizu broja ponovaka CCTG u genu CNBP. Master rad. Biološki fakultet, Univerzitet u Beogradu. 2014.Komisija: dr Dušanka Savić-Pavićević (mentor), dr Goran Brajušković, Jovan Pešović.

5. Jovan Pešović. Povezanost mutacija u genu za distrofin sa kognitivnim poremećajima kod bolesnika sa Dišenovom mišićnom distrofijom. Master rad. Biološki fakultet, Univerzitet u Beogradu. 2013.Komisija: dr Dušanka Savić-Pavićević (mentor), dr Vedrana Milić Rašić, dr Goran Brajušković.

6. Vanja Tomić. Vrste i zastupljenost numeričkih hromozomskih aberacija u nalazima kariotipa ploda na području Republike Srpske u periodu od januara 2009. do aprila 2013. godine. Master rad. Biološki fakultet, Univerzitet u Beogradu. 2013.

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Komisija: dr Dušanka Savić-Pavićević (mentor), dr Goran Brajušković.

7. Mirjana Novković. Genetička studija asocijacije varijanti u promotoru gena za triptofan hidroksilazu sa izvršenjem samoubistva. Diplomski rad. Biološki fakultet, Univerzitet u Beogradu. 2012.Komisija: dr Dušanka Savić-Pavićević (mentor), dr Goran Brajušković.

8. Maša Ivin. Studija asocijacije varijanti u genu ADARB1 — rs11088983, rs2838817 i rs4818766 — sa šizofrenijom. Master rad. Biološki fakultet, Univerzitet u Beogradu. 2012.Komisija: dr Dušanka Savić-Pavićević (mentor), dr Maja Ivković, dr Goran Brajušković.

9. Svetlana Đurica. Studija asocijacije varijanti u genu ADARB1 — rs11088983, rs2838817 i rs4818766 — sa unipolarnom i bipolarnom depresijom. Master rad. Biološki fakultet, Univerzitet u Beogradu. 2012.Komisija: dr Dušanka Savić-Pavićević (mentor), dr Maja Ivković, dr Goran Brajušković.

10. Marija Jovanović. Uticaj zračenja na ekspresiju miRNK u ćelijskim linijama kancera dojke. Diplomski rad. Biološki fakultet, Univerzitet u Beogradu. 2012.Komisija: dr Dušanka Savić-Pavićević (mentor), dr Goran Brajušković.

11. Miloš Brkušanin. Studija genetičke asocijacije polimorfizama G-703T i T437A u promotoru gena za triptofan hidroksilazu 2 sa depresijom. Diplomski rad. Biološki fakultet, Univerzitet u Beogradu. 2011.Komisija: dr Dušanka Savić-Pavićević (mentor), dr Goran Brajušković.

***12. Denis Krndija. Analiza haplotipa DM1 lokusa u jugoslovenskoj populaciji. Diplomski

rad. Biološki fakultet, Univerzitet u Beogradu. 2003.Komisija: mr Dušanka Savić (mentor), dr Stanka Romac.

Mentor sa fakulteta – odbranjen diplomski ili master radNakon izbora 24x2=48

Ukupno 32x2=64

1. Jovana Milenković. Studija asocijacije genetičkih varijanti u genu APOE sa parametrima lipidnog statusa i težinom kliničke prezentacije kod bolesnika sa multiplom sklerozom. Master rad. Biološki fakultet, Univerzitet u Beogradu. 2016.Komisija: dr Maja Živković (mentor) dr Dušanka Savić-Pavićević (mentor), dr Ljilјana Stojković.

2. Tamara Kovačević. Uticaj inhibitora kinaza mTOR signalnog puta na rano embrionalno razviće zebrice. Master rad. Biološki fakultet, Univerzitet u Beogradu. 2016.Komisija: dr Aleksandra Divac Rankov (mentor), dr Dušanka Savić-Pavićević (mentor), dr Jelena Dinić.

3. Ana Kojić. Karakterizacija regulatornog proteina ANKRD1 u ćelijskim linijama glioblastoma U87-MG i LN229. Master rad. Biološki fakultet, Univerzitet u Beogradu. 2016.Komisija: dr Dragica Radojković (mentor), dr Dušanka Savić-Pavićević (mentor).

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4. Marija Branković. Analiza gena NPC2 kod bolesnika sa Niman-Pikovom bolešću tipa C. Master rad. Biološki fakultet, Univerzitet u Beogradu. 2016.Komisija: dr Valerija Dobričić (mentor), dr Dušanka Savić-Pavićević (mentor), dr Ivana Novaković.

5. Katarina Jović. Analiza egzona 12, 18, 19, 20 i 21 gena ATP7B kod bolesnika sa Vilsonovom bolešću. Master rad. Biološki fakultet, Univerzitet u Beogradu. 2016.Komisija: dr Valerija Dobričić (mentor), dr Dušanka Savić-Pavićević (mentor), dr Ivana Novaković.

6. Jovana Despotović. Analiza efekta povećane ekspresije gena SOX3 na karakteristike U87 i U251 ćelijskih linija glioblastoma. Master rad. Biološki fakultet, Univerzitet u Beogradu. 2015.Komisija: dr Danijela Drakulić (mentor), dr Dušanka Savić-Pavićević (mentor), dr Milena Stevanović.

7. Marija Dragojević. Ispitivanje uticaja FII c.1824C>T varijante na količinu iRNK za protrombin u nukleusu i citoplazmi na modelu stabilno transfektovanih Cos-7 ćelija. Master rad. Biološki fakultet, Univerzitet u Beogradu. 2015.Komisija: dr Iva Pruner (mentor), dr Dušanka Savić-Pavićević (mentor), dr Branko Tomić.

8. Aleksej Drino. Korelacija mutacionog statusa gena ATM i TP53 sa mutacionim statusima gena uključenih u proces neoplastične transformacije kod bolesnika sa primarnim limfomom centralnog nervnog sistema. Master rad. Biološki fakultet, Univerzitet u Beogradu. 2015.Komisija: dr Bojana Stanić (mentor), dr Dušanka Savić-Pavićević (mentor), dr Sonja Pavlović.

9. Marija Gredić. Konstruisanje i funkcionalna analiza mutiranih formi humanog proteína SOX14. Master rad. Biološki fakultet, Univerzitet u Beogradu. 2015.Komisija: dr Jelena Popović (mentor), dr Dušanka Savić-Pavićević (mentor), dr Milena Stevanović.

10. Marina Anđelković. Uticaj varijanti gena NRAMP1 i VDR na izmenjenu funkciju makrofaga kod pacijenata sa tuberkulozom. Master rad. Biološki fakultet, Univerzitet u Beogradu. 2014.Komisija: dr Vesna Spasovski (mentor), dr Dušanka Savić-Pavićević (mentor).

11. Danica Bajić. Interakcije Wnt/β-katenin signalnog puta i SOXB1 gena u humanim NT2/D1 ćelijama. Master rad. Biološki fakultet, Univerzitet u Beogradu. 2014.Komisija: dr Marija Mojsin (mentor), dr Dušanka Savić-Pavićević (mentor), dr Milena Stevanović.

12. Marija Sinadinović. Pozitivan efekat hemokina CXCL12 na preživljavanje beta ćelija pankreasa: uticaj na ekspresiju i aktivnost katalaze. Master rad. Biološki fakultet, Univerzitet u Beogradu. 2014.Komisija: dr Nevena Grdović (mentor), dr Dušanka Savić-Pavićević (mentor), dr Svetlana Dinić.

13. Marija Petrić. Zebrica (Danio rerio) kao model sistem za ispitivanje delovanja induktora autofagije. Master rad. Biološki fakultet, Univerzitet u Beogradu. 2014.Komisija: dr Aleksandra Divac Rankov (mentor), dr Dušanka Savić-Pavićević (mentor), dr Mila Ljujić.

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14. Jovana Rajić. Analiza metilacionog profila promotora gena za CXCL12 u parodontopatiji i dijabetičnoj paradontopatiji. Master rad. Biološki fakultet, Univerzitet u Beogradu. 2014.Komisija: dr Jelena Arambašić Jovanović (mentor), dr Dušanka Savić-Pavićević (mentor), dr Melita Vidaković.

15. Darija Lončarić. Analiza hipermetilacije promotora P16 i P14 tumor supresorskih gena u mukoepidermoidnom karcinomu pljuvačnih žlezda. Master rad. Biološki fakultet, Univerzitet u Beogradu. 2014.Komisija: dr Jelena Milašin (mentor), dr Dušanka Savić-Pavićević (mentor).

16. Anja Tolić. Analiza metilacionog statusa gena za CXCL12 kod pacova. Master rad. Biološki fakultet, Univerzitet u Beogradu. 2013.Komisija: dr Aleksandra Uskoković (mentor), dr Dušanka Savić-Pavićević (mentor), dr Jelena Arambašić, dr Melita Vidaković.

17. Sanja Tomašević. Varijabilnost nukleotidne sekvence u genomu virusa hepatitisa C u korelaciji sa odgovorom na standardnu antivirusnu terapiju. Diplomski rad. Biološki fakultet, Univerzitet u Beogradu. 2013.Komisija: dr Snežana Jovanović-Čupić (mentor), dr Dušanka Savić-Pavićević (mentor), mr Milena Krajnović.

18. Marijana Arađanski. Polimorfizmi u 3 kraju gena za protrombin kod pacijenata sa idiopatskom trombofilijom. Master rad. Biološki fakultet, Univerzitet u Beogradu. 2013.Komisija: dr Valentina Đorđević (mentor), dr Dušanka Savić-Pavićević (mentor), dr Dragica Radojković.

19. Jelena Stanišić. Ispitivanje citotoksične aktivnosti novosintetisanih kompleksa Zn(II) na različitim tumorskim ćelijskim linijama. Diplomski rad. Biološki fakultet, Univerzitet u Beogradu. 2013.Komisija: dr Siniša Radulović (mentor), dr Dušanka Savić-Pavićević (mentor).

20. Mina Noshy Takawy. Poremećaj apoptoze kao uzrok akumulacije maligno izmenjenih granulocita u mijeloproliferativnim neoplazmama. Master rad. Biološki fakultet, Univerzitet u Beogradu. 2013.Komisija: dr Vesna Spasovski (mentor), dr Dušanka Savić-Pavićević (mentor), dr Branka Zukić.

21. Iva Lučić. Polimorfizmi CYP2C9*2 i CYP2C9*3 gena za citohrom P450 2C9 u predviđanju optimalne terapijske doze kumarinskih derivata. Master rad. Biološki fakultet, Univerzitet u Beogradu. 2012.Komisija: dr Ljiljana Rakićević (mentor), dr Dušanka Savić-Pavićević (mentor), dr Dragica Radojković.

22. Vladimir Đurđević. Asocijacija polimorfizama GSTM1 i GSTT1 sa karotidnom aterosklerozom u populaciji Srbije. Diplomski rad. Biološki fakultet, Univerzitet u Beogradu. 2012.Komisija: dr Tamara Đurić Denić (mentor), dr Dušanka Savić-Pavićević (mentor).

23. Marija Majstorović. Uloga polimorfizma-799 C/T u genu za MMP-8 u nastanku ožiljaka na bubrezima kod dece sa kongenitalnim anomalijama bubrega i uretera i akutnim pijelonefritisom. Diplomski rad. Biološki fakultet, Univerzitet u Beogradu. 2011.Komisija: dr Aleksandra Stanković (mentor), dr Dušanka Savić-Pavićević (mentor).

8

24. Maja Bošković. Komparacija efikasnosti determinacije pola kod ptica iz dva tipa uzorka (pera i brisa usne duplje) analizom polno vezanog CHD gena. Diplomski rad. Biološki fakultet, Univerzitet u Beogradu. 2011.Komisija: dr Jevrosima Stevanović (mentor), dr Dušanka Savić-Pavićević (mentor).

***25. Irena Zurnić. Ekspresija gena GATA2 i BMP4 u humanim uzorcima kongenitalnih

anomalija urogenitalnog sistema. Diplomski rad. Biološki fakultet, Univerzitet u Beogradu. 2010.Komisija: dr Aleksandra Stanković (mentor), dr Dušanka Savić-Pavićević (mentor).

26. Dragana Slavković. Polimorfizam kodona 72 p53 tumor supresor gena kod bolesnica sa karcinomom jajnika. Diplomski rad. Biološki fakultet, Univerzitet u Beogradu. 2008.Komisija: dr Radmila Janković (mentor), dr Dušanka Savić-Pavićević (mentor).

27. Maša Umićević. Polimorfizam DNK G894T u genu za endotelijalnu azot oksid sintazu (eNOS) kao faktor rizika za aterosklerozu karotida. Diplomski rad. Biološki fakultet, Univerzitet u Beogradu. 2008.Komisija: dr Tamara Đurić (mentor), dr Dušanka Savić-Pavićević (mentor).

28. Dragana Dobrijević. Kloniranje 2S albumina kikirikija. Diplomski rad. Biološki fakultet, Univerzitet u Beogradu. 2008.Komisija: dr Tanja Ćirković Veličković (mentor), dr Dušanka Savić-Pavićević (mentor).

29. Jelena Prokopović. Mehanizmi odbrane ćelija humanog kancera prostate od oksidativnog stresa. Diplomski rad. Biološki fakultet, Univerzitet u Beogradu. 2006.Komisija: mr Ana Nićiforović (mentor), dr Dušanka Savić-Pavićević (mentor).

30. Aleksandar Raković. Analiza polimorfizama Asn291Ser, Asp9Asn i Ser447Stop u genu za lipoproteinsku liazu kao potencijalnih markera hipertrigliceridemije: studija familije. Diplomski rad. Biološki fakultet, Univerzitet u Beogradu. 2006.Komisija: dr Aleksandra Stanković (mentor), dr Dušanka Savić-Pavićević (mentor).

31. Žarko Ivanović. Promene u asocijaciji proteina reparacionog sistema sa jedarnim matriksom limfocita pacova nakon dejstva X-zraka. Diplomski rad. Biološki fakultet, Univerzitet u Beogradu. 2005.Komisija: dr Melita Vidaković (mentor), dr Dušanka Savić-Pavićević (mentor), dr Vesna Martinović.

32. Miloš Pjanić. Uticaj tačkastih polimorfizama u APOE i HL genima na pojavu dijabetes melitusa tip 2. Diplomski rad. Biološki fakultet, Univerzitet u Beogradu. 2005.Komisija: dr Stanka Romac (mentor), dr Dušanka Savić-Pavićević (mentor).

Učešće u komisiji za odbranu doktorske disertacijeNakon izbora 12x4=48

Ukupno 15x4=60

1. Maja Gvozdenov. Funkcionalna analiza genskih varijanti FIIc.1787G>A (protrombin Beograd) i FIIc.*64_*66del i njihova povezanost sa trombofilijom. Doktorska disertacija. Biološki fakultet, Univerzitet u Beogradu. 2017.Komisija: dr Valentina Đorđević (mentor), dr Dragica Radojković (mentor), dr Dušanka Savić-Pavićević.

9

2. Zorana Nikolić. Studija asocijacije varijanti u genima za mikroRNK i za proteine utišavajućeg kompleksa sa rizikom za razvoj i progresiju karcinoma prostate kod bolesnika iz Srbije. Doktorska disertacija. Biološki fakultet, Univerzitet u Beogradu. 2017.Komisija: dr Goran Brajušković (mentor), dr Dušanka Savić-Pavićević, dr Milena Krainović, dr Nikola Tanić.

3. Jovana Jasnic. Određivanje profila ekspresije i unutarćelijske lokalizacije proteina ANKRD2 u srcu i skeletnim mišićima čoveka. Doktorska disertacija. Biološki fakultet, Univerzitet u Beogradu. 2016.Komisija: dr Snežana Kojić (mentor), dr Dragica Radojković (mentor), dr Dušanka Savić-Pavićević.

4. Ana Tošić. Filogeografski status i genetička struktura populacija potočne pastrmke (Salmo cf. trutta) Ðerdapa i Timočke krajine. Doktorska disertacija. Biološki fakultet, Univerzitet u Beogradu. 2016.Mentor: dr Predrag Simonović

Komisija: dr Dušanka Savić-Pavićević, dr Tea Tomljanović, dr Danilo Mrdak.

5. Nikola Kotur. Farmakogenetika 6-merkaptopurina i metotreksata u dečjoj akutnoj limfoblastnoj leukemiji. Doktorska disertacija. Biološki fakultet, Univerzitet u Beogradu. 2015.Komisija: dr Branka Zukić (mentor), dr Sonja Pavlović (mentor), dr Dušanka Savić-Pavićević.

6. Sanja Srzentić. Molekularni markeri poremećaja koagulacije, inflamacije, apoptoze, formiranja i remodelovanja koštanog tkiva kod Leg-Kalve-Pertesove bolesti. Doktorska disertacija. Biološki fakultet, Univerzitet u Beogradu. 2015.Komisija: dr Gordana Nikčević (mentor), dr Sonja Pavlović (mentor), dr Dušanka Savić-Pavićević.

7. Kristel Klaassen. Uticaj varijanti u kodirajućim i nekodirajućim regionima gena uzročnika i gena modifikatora na fenotip pacijenata sa hiperfenilalaninemijom. Doktorska disertacija. Biološki fakultet, Univerzitet u Beogradu. 2015.Komisija: dr Maja Stojiljković (mentor), dr Sonja Pavlović (mentor), dr Dušanka Savić-Pavićević, dr Belen Perez, dr Goran Brajušković.

8. Nina Petrović. MikroRNA-21 kao indikator invazivnosti karcinoma dojke kod pacijenata sa različitim statusom estrogenskog i progesteronskog receptora. Doktorska disertacija. Biološki fakultet, Univerzitet u Beogradu. 2014.Komisija: dr Vesna Mandušić (mentor), dr Goran Brajušković (mentor), dr Dušanka Savić-Pavićević, dr Boban Stanojević.

9. Jelena Žakula. Inaktivacija ćelija melanoma čoveka zračenjem jonima ugljenika: određivanje radiobioloških parametara i analiza signalnih puteva ćelijske smrti. Doktorska disertacija. Biološki fakultet, Univerzitet u Beogradu. 2014.Komisija: dr Lela Korićanac (mentor), dr Goran Brajušković (mentor), dr Ivan Petrović, dr Dušanka Savić-Pavićević.

10. Ana Branković. Studija asocijacije genetičkih varijanti u regionima 7q36, 8q24 i 17q12 sa rizikom za razvoj i progresiju karcinoma prostate. Doktorska disertacija. Biološki fakultet, Univerzitet u Beogradu. 2014.Komisija: dr Goran Brajušković (mentor), dr Dušanka Savić-Pavićević, dr Vinka Vukotić.

10

11. mr Dušan Keckarević. Molekularno genetička osnova amiotrofične lateralne skleroze kod pacijenata u populaciji Srbije. Doktorska disertacija. Biološki fakultet, Univerzitet u Beogradu. 2011.Komisija: dr Stanka Romac (mentor), dr Zorica Stević (mentor), dr Pavle Anđus, dr Dušanka Savić-Pavićević, dr Goran Brajušković, dr Slobodanka Todorović.

12. mr Miljana Kecmanović. Molekularno genetička analiza različitih tipova progresivnih miokloničnih epilepsija u populaciji Srbije. Doktorska disertacija. Biološki fakultet, Univerzitet u Beogradu. 2011.Komisija: dr Stanka Romac (mentor), dr Dušanka Savić-Pavićević, dr Goran Brajušković, dr Nebojša Jović.

***13. mr Milica Keckarević Marković. Molekularno genetička osnova hereditarne motorne i

senzorne neuropatije tip 1 (HMSN1) kod pacijenata u populaciji Srbije. Doktorska disertacija. Biološki fakultet, Univerzitet u Beogradu. 2010.Komisija: dr Stanka Romac (mentor), dr Slobodanka Todorović, dr Vedrana Milić Rašić, dr Dušanka Savić-Pavićević, dr Goran Brajušković.

14. Marizela Šarić. Molekularna genetika hereditarne hemohromatoze tip 1 i 2. Doktorska disertacija. Biološki fakultet, Univerzitet u Beogradu. 2008.Komisija: dr Stanka Romac (mentor), dr Dušanka Savić-Pavićević, dr Goran Brajušković, dr Jasna Jović.

15. mr Ana Đarmati. Genetička osnova Parkinsonove bolesti sa ranim početkom u populaciji Srbije i Crne Gore. Doktorska disertacija. Biološki fakultet, Univerzitet u Beogradu. 2006.Komisija za odbranu: dr Stanka Romac (mentor), dr Vladimir Kostić, dr Dušanka Savić-Pavićević.

Učešće u komisiji za odbranu magistarskog radaNakon izbora 0

Ukupno 3x3=9***

1. Miroslav Adžić. Sistemski odgovor na prisustvo tumora i na terapiju citostaticima i jonizujućim zračenjem kod kancera dojke. Magistarski rad. Biološki fakultet, Univerzitet u Beogradu. 2006.Komisija: dr Marija Radojčić (mentor), dr Stanka Romac (mentor), dr Dušanka Savić-Pavićević.

2. Ljubica Zamurović. Molekularno genetička analiza gena kod pacijenata obolelih od shizofrenije: TH01, RAI1 i PCQAP lokusa. Magistarski rad. Biološki fakultet, Univerzitet u Beogradu. 2006.Komisija: dr Stanka Romac (mentor), dr Dušanka Savić-Pavićević, dr Goran Brajušković.

3. Valerija Dobričić. Longitudalna studija ekspanzija GAA ponovaka u genu za frataksin. Magistarski rad. Biološki fakultet, Univerzitet u Beogradu. 2005.Komisija: dr Stanka Romac (mentor), dr Dušanka Savić-Pavićević, dr Slobodanka Tododrović.

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Učešće u komisiji za odbranu diplomskog ili master radaNakon izbora 19x1=19

Ukupno 25x1=25

1. Saša Ćurić. Citotoksični efekat specifičnog inhibitora fosfatidil inozitol 3-kinaze PIK-75 na ćelije osteosarkoma čoveka. Master rad. Biološki fakultet, Univerzitet u Beogradu. 2016.Komisija: dr Goran Brajušković (mentor), dr Dušanka Savić-Pavićević.

2. Uroš Janković. CD104 kao marker stem ćelija karcinoma dojke. Diplomski rad. Biološki fakultet, Univerzitet u Beogradu. 2016.Komisija: dr Goran Brajušković (mentor), dr Dušanka Savić-Pavićević, Miloš Brkušanin.

3. Nevena Kotarac. Primena metode amplifikacije višestruko ligiranih proba u identifikaciji mikordelecija i varijacija u broju kopija regiona AZF hromozoma Y kod muškaraca sa idiopatskim sterilitetom. Master rad. Biološki fakultet, Univerzitet u Beogradu. 2016.Komisija: dr Goran Brajušković (mentor), dr Dušanka Savić-Pavićević, Nemanja Vučić.

4. Nevena Šajinović. Značaj analize mutacionog statusa gena HER2 u izboru terapijskog pristupa kod bolesnica sa invanzivnim karicnomom dojke. Master rad. Biološki fakultet, Univerzitet u Beogradu. 2016.Komisija: dr Goran Brajušković (mentor), dr Dušanka Savić-Pavićević, Miloš Brkušanin.

5. Stefan Cidilko. Studija asocijacije genetičkih varijanti rs3746444 u genu has-miR-499 i rs3742330 u genu DICER1 sa rizikom za razvoj i progresiju karcinoma prostate u populaciji Srbije. Master rad. Biološki fakultet, Univerzitet u Beogradu. 2015.Komisija: dr Goran Brajušković (mentor), dr Dušanka Savić-Pavićević, Zorana Nikolić.

6. Ana Filipović. Značaj tačkastih polimorfizama kao novih bioloških markera za dijagnostiku i praćenje karcinoma prostate. Diplomski rad. Biološki fakultet, Univerzitet u Beogradu. 2014.Komisija: dr Goran Brajušković (mentor), dr Dušanka Savić-Pavićević, Zorana Nikolić.

7. Olja Labus. Analiza heksanukleotidnih ponovaka GGGGCC u prvom intronu gena C9orf72 u populaciji Srbije. Master rad. Biološki fakultet, Univerzitet u Beogradu. 2014.Komisija: dr Dušan Keckarević (mentor), dr Dušanka Savić-Pavićević, dr Milica Keckarević Marković.

8. Nemanja Vučić. Studija asocijacije genetičkih varijanti rs1799983 i rs2070744 u genu za NOS3 sa pojavom steriliteta u populaciji Srbije. Master rad. Biološki fakultet, Univerzitet u Beogradu. 2014.Komisija: dr Goran Brajušković (mentor), dr Dušanka Savić-Pavićević, Zorana Nikolić.

9. Đorđe Milošević. Meta-analiza asocijacije genetičkih varijanti u genu za NOS3 sa rizikom za razvoj karcinoma prostate. Diplomski rad. Biološki fakultet, Univerzitet u Beogradu. 2014.Komisija: dr Goran Brajušković (mentor), dr Dušanka Savić-Pavićević, Zorana Nikolić.

10. Biljana Pokimica. Analiza mutacije V600E u genu BRAF kod bolesnika sa oralnim skvamocelularnim karcinomom. Master rad. Biološki fakultet, Univerzitet u Beogradu. 2013.Komisija: dr Zvonko Magić (mentor), dr Goran Brajušković (mentor), dr Dušanka Savić-Pavićević.

12

11. Ivan Skadrić. Populaciono genetička studija inserciono-delecionih polimorfizama u lokalnim zajednicama ljudi u Srbiji i regionu. Master rad. Biološki fakultet, Univerzitet u Beogradu. 2013.Komisija: dr Biljana Stojković (mentor), dr Dušanka Savić-Pavićević, dr Oliver Stojković.

12. Stefan Preković. Analiza asocijacije genetičkih varijanti rs3760511 i rs7501939 sa karcinomom prostate. Master rad. Biološki fakultet, Univerzitet u Beogradu. 2013.Komisija: dr Goran Brajušković (mentor), dr Dušanka Savić-Pavićević, Zorana Nikolić.

13. Sanja Radović. Analiza indikacija za prenatalnu dijagnostiku kariotipa kod trudnica sa predisponirajućim faktorima za rizičnu trudnoću na teritoriji grada Novog Sada. Diplomski rad. Biološki fakultet, Univerzitet u Beogradu. 2013.Komisija: dr Goran Brajušković (mentor), dr Dušanka Savić-Pavićević.

14. Miša Vreća. Asocijacija genetičke varijante rs1799983 sa karcinomom prostate u populaciji Srbije. Diplomski rad. Biološki fakultet, Univerzitet u Beogradu. 2012.Komisija: dr Goran Brajušković (mentor), dr Dušanka Savić-Pavićević.

15. Aleksandar Kojić. Asocijacija genetičke varijante rs378854 sa karcinomom prostate u populaciji Srbije. Master rad. Biološki fakultet, Univerzitet u Beogradu. 2012.Komisija: dr Goran Brajušković (mentor), dr Dušanka Savić-Pavićević.

16. Zorana Nikolić. Asocijacija genetičke varijante rs3787016 sa karcinomom prostate u populaciji Srbije. Master rad. Biološki fakultet, Univerzitet u Beogradu. 2012.Komisija: dr Goran Brajušković (mentor), dr Dušanka Savić-Pavićević.

17. Kalaba Predrag. Analiza dva tačkasta polimorfizma lokusa 8q24 kod bolesnika sa karcinomom prostate u populaciji Srbije. Završni rad. Hemijski fakultet, Univerzitet u Beogradu. 2012.Komisija: dr Goran Brajušković (mentor), dr Dušanka Savić-Pavićević.

18. Mihailo Mirković. Analiza tačkastog polimorfizma rs 3760511 lokusa 17q12 kod bolesnika sa karcinomom prostate u srpskoj populaciji. Diplomski rad. Biološki fakultet, Univerzitet u Beogradu. 2011.Komisija: dr Goran Brajušković (mentor), dr Dušanka Savić-Pavićević, Jelena Karanović.

19. Ivan Stanković. Analiza tačkastog polimorfizma rs7501939 lokusa 17q12 kod bolesnika sa karcinomom prostate u srpskoj populaciji. Diplomski rad. Biološki fakultet, Univerzitet u Beogradu. 2011.Komisija: dr Goran Brajušković (mentor), dr Dušanka Savić-Pavićević.

***20. Biljana Petrićević. Povezanost tačkastih polimorfizama u promotorskom regionu gena

za NOS3 sa progresijom karcinoma prostate. Diplomski rad. Biološki fakultet, Univerzitet u Beogradu. 2010.Komisija: dr Goran Brajušković (mentor), dr Dušanka Savić-Pavićević, Jelena Karanović.

21. Miloš Diklić. Molekularno genetička manipulacija hloroplastom DNK hrastova. Diplomski rad. Hemijski fakultet, Univerzitet u Beogradu. 2009.Komisija: dr Ljuba Mandić (mentor), dr Goran Brajušković (mentor), dr Dušanka Savić-Pavićević.

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22. Vesna Vuković. Uticaj M55L tačkastog polimorfizma u PON 1 genu na pojavu dijabetes mellitus-a tipa 2. Diplomski rad. Biološki fakultet, Univerzitet u Beogradu. 2006.Komisija: dr Stanka Romac (mentor), dr Dušanka Savić-Pavićević.

23. Ksenija Jakovljević. Detekcija amplifikacije c-myc onkogena diferencijalnim PCR-om u karcinomima jajnika. Diplomski rad. Biološki fakultet, Univerzitet u Beogradu. 2006.Komisija: dr Mirjana Branković-Magić (mentor), dr Stanka Romac (mentor), dr Dušanka Savić-Pavićević.

24. Tijana Borovski. Distribucija HPRTB, D2C1338, D19C433 mikrosatelitskih lokusa u populaciji SCG. Diplomski rad. Biološki fakultet, Univerzitet u Beogradu. 2006.Komisija: mr Dušan Keckarević (mentor), dr Dušanka Savić-Pavićević.

25. Ranković Vladan. Šizofrenija i polimorfni regioni CAG ponovaka u genu za kalcijumom aktivirani jonski kanal niske provodljivosti tipa 3 (hSKCa3) u srpskoj populaciji. Diplomski rad. Biološki fakultet, Univerzitet u Beogradu. 2004.Komisija: dr Stanka Romac (mentor), dr Dušanka Savić-Pavićević.

Držanje nastave na kursu – u potpunosti pripremljen nastavni program

Nakon izbora 3x6=18Ukupno 6x6=36

1. Molekularna biologija ćelije, Osnovne akademske studije, studijska grupa Molekularna biologija i fiziologija (2012–) – u saradnji sa prof. A. Korać i prof. G. Brajuškovićem

2. Molekularna genetika humanih bolesti (2016–), prethodno Uvod u molekularnu dijagnostiku humanih bolesti (2012-2016), Master akademske studije, modul Humana molekularna biologija

3. Molekularna neurobiologija, Master akademske studije, modul Neurobiologija (2012–) – u saradnji sa prof. P. Anđusom

***4. Osnovi molekularne biologije, Osnovne akademske studije, studijske grupe Biologija i

Molekularna biologija i fiziologija (2008–) i Ekologija (2008-2012) – u saradnji sa prof. G. Matić

5. Viši kurs molekularne biologije, Osnovne akademske studije, studijska grupa Molekularna biologija i fiziologija (2010-2012) – u saradnji sa prof. G. Brajuškovićem

6. Molekularna osnova neuromišićnih i psihijatrijskih bolesti (2012– ), prethodno Molekularna biologija neuroloških i psihijatrijskih bolesti (2006-2011), doktorske akademske studije, program Molekularna biologija, modul Molekularna biologija eukariota – u saradnji sa prof. S. Romac i dr S. Kojić

Držanje nastave na kursu – pripremljena dopuna nastavnog programa


1. Molekularna biologija eukariota, Osnovne akademske studije, studijska grupa Molekularna biologija i fiziologija (2011–) – nastavni program dopunjem novim saznanjima o RNK svetu eukariotskih ćelija

***

14

2. Osnovi molekularne biologije, Studijske grupe Biologija i Profesor za biologiju i hemiju, Univerzitet u Beogradu-Biološki fakultet (2005-2008), i Biohemija Univerzitet u Beogradu-Hemijski fakultet (2005-2012)

Držanje nastave na kursu – učešće u realizaciji praktične nastave na kursu po školskoj godini

Nakon izbora 0Ukupno 1x16=16

***1. Osnovi molekularne biologije, Osnovne studije, studijske grupe Molekularna biologija i

fiziologija, i studijska grupa Biohemija (Univerzitet u Beogradu-Hemijski fakultet) (2000-2005) (5 poena)

2. Molekularna biologija eukariota, Osnovne studije, studijska grupa Molekularna biologija i fiziologija (2000-2007) (6 poena) – osmislila vežbe koje se po originalnom konceptu sa unapređenim metodama i danas izvode

3. Molekularna genetika, Osnovne studije, studijska grupa Molekularna biologija i fiziologija, i studijska grupa Biohemija (Univerzitet u Beogradu-Hemijski fakultet) (2000-2005) (5 poena) – osmislila teorijske vežbe

Držanje nastave na kursu – učešće na drugim kursevima

1. Predavač na doktorskim akademskim studijama, program Molekularna biologija.

Kursevi: Molekularna biologija gena (2009–), Metodološki pristupi u molekularnoj biologiji (2008–), Molekularna genetika bolesti čoveka (2010–)

***2. Predavač na poslediplomskim studijama, smer Molekularna biologija i biohemija.

Kursevi: Molekulski regulacioni mehanizmi i Molekularna biologija eukariota – viši kurs (2000-2005)

2.3. Ostale nastavne aktivnosti

Držanje nastave za stručno usavršavanje nastavnika osnovnih i srednjih škola


1. MOLEKULARNA BIOLOGIJA – lakšim putem do funkcionalnog znanja. Akreditovani seminar; Zavod za unapređivanje obrazovanja i vaspitanja R Srbije; kataloški brojevi K890791-1 (2014/15), 892 (2015/16) i 618 (2016/17 i 2017/18).Datumi i mesta održavanja seminara: 25.02.2017., 04.06.2016., 12.03.2016. i 25.04.2015. u Beogradu i 06.06.2015. u Užicama

Učešće u pedagoškom radu sa učenicima osnovnih i srednjih školaNakon izbora 1x1=1

Ukupno 1x1=1

1. Seminar Biologija, Istraživačka stanica Petnica, Petnica, Srbija, 13.02.2016. Predavanje: RNK svet eukariotske ćelije.

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Recenzija udžbenika kategorije M90Nakon izbora 2x3=6

Ukupno 2x3=6

1. Brajušković G. Molekularna biologija 2. Beograd: Savremena administracija. 2012. ISBN 978-86-387-0803-1.

2. Stojković B, Tucić N. Od molekula do organizma: molekularna i fenotipska evolucija. Beograd: Službeni glasnik. 2012. ISBN 978-86-519-1408-2.

Recenzija ostalih publikacija kategorije M90Nakon izbora 1x1=1

Ukupno 1x1=1

1. Radović S, Lozo J, Keckarević D. Eksperimentalna biohemija – praktikum. Beograd: Biološki fakultet, Univerzitet u Beogradu. 2011. ISBN 978-86-7078-074-3.

Članstvo u organizacionim odborima međunarodnih/nacionalnih/stručnih skupovaNakon izbora 3,5

Ukupno 3,5

1. Prvi kongres molekularnih biologa Srbije sa međunarodnim učešćem (CoMBoS); 20-22. septembar 2017; Beograd, Srbija.Član Naučnog odbora i član Organizacionog odbora (1 poen)

2. Conference on Structure and Dynamics of the Sarcomere; 2016 May 4-6; Belgrade, Serbia. Član Naučnog odbora (2 poena)

3. Prva petnička škola molekularne biologije – PCR u biološkim i biomedicinskim istraživanjima; 02-07. oktobar 2016; Istraživačka stanica Petnica, Petnica, Srbija. Organizator (0,5 poena)

Studentsko vrednovanje studiranja i nastave

Školska godinaKurs 2010/11 2011/12 2012/13 2013/14 2014/15 2015/16Osnovne studijeOsnovi molekularne biologije 4,351 4,132 4,273 4,894 4,504 4,395

Molekularna biologija eukariota 4,85 4,92 4,97 4,83 4,89 4,86Molekularna biologija ćelije – 4,80 4,36 4,75 4,83 4,77Master studijeUvod u mol. dijagnostiku humanih bolesti – – – – 4,91 4,91Molekularna neurobiologija – – – – – 4,87

Prosečna ocena 4,70

1Prosečna ocena studijskih grupa (Molekularna biologija i fiziologija – 4,66; Biologija – 4,13; Ekologija – 4,38; Biohemija – 4,31)

2Prosečna ocena studijskih grupa (Molekularna biologija i fiziologija – 4,34; Biologija – 3,91)3Prosečna ocena studijskih grupa (Molekularna biologija i fiziologija – 4,63; Biologija – 4,65)4Ocena studijske grupe Molekularna biologija i fiziologija 5Prosečna ocena studijskih grupa (Molekularna biologija i fiziologija – 4,72; Biologija – 4,06)

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3. NAUČNI RAD

3.1. Kvantitativan prikaz postignutih rezultata naučnog rada

Vrsta rezultata Vrednost Broj Poeni Broj PoeniPosle izbora Ukupno

Osnovne naučne aktivnosti

М14 Monografska studija/poglavlje u knjizi М12 ili rad u tematskom zborniku međunarodnog značaja 4 2 8 2 8

М21а Rad u međunarodnom časopisu izuzetnih vrednosti 10 2 20 2 20М21 Rad u vrhunskom međunarodnom časopisu 8 10 80 16 128М22 Rad u istaknutom međunarodnom časopisu 5 12 60 24 120М23 Rad u međunarodnom časopisu 3 5 15 13 39

М24 Rad u časopisu međunarodnog značaja verifikovanog posebnom odlukom 2 – 0 1 2

– Rad u časopisu van JCR liste 0 2 0 5 0М34 Saopštenje se međunarodnog skupa štampano u celini 0.5 40 20 54 27

М45 Poglavlje u knjizi M42 ili rad u tematskom zborniku nacionalnog značaja 1.5 1 1.5 2 3

М52 Rad u časopisu nacionalnog značaja 1.5 1 1.5 1 1.5

М61 Predavanje po pozivu sa skupa nacionalnog značaja štampano u celini 1.5 2 3 4 6

М62 Predavanje po pozivu sa skupa nacionalnog značaja štampano u izvodu 1 3 3 3 3

М64 Saopštenje sa skupa nacionalnog značaja štampano u izvodu 0.2 20 4 29 5.8

M66a Stručni rad, naučno-popularni i popularni radovi 0.2 – 0 2 0.4М71 Odbranjena doktorska teza 6 – 0 1 6М72 Odbranjen magistarski rad 3 – 0 1 3

Ukupno 69 372.7Ostale naučne aktivnostiUčešće na međunarodnom projektu 2 2 4 2 4Rukovođenje projektom bilateralne saradnje 2 1 2 1 2Učešće u projektima bilateralne saradnje 1 2 2 2 2Rukovođenje nacionalnim projektom 4 1 4 1 4Učešće u nacionalnom projektu 1 – 0 4 4Recenzija publikacija kategorije M20 1.5 12 18 13 19.5Članstvo u uredništu međunarodnih/nacionalnih časopisa/zbornika radova sa naučnih skupova 3/1/0.5 2 3.5 2 3.5

Citiranost na SCI listi 0.1 277 27.7 277 27.7Ukupno 61.2 66.7

Ukupno osnovne i ostale naučne aktivnosti 277.2 439.4

Prema Pravilniku o kriterijumima za pokretanje postupka za sticanje nastavničkih zvanja na Univerzitetu u Beogradu – Biološkom fakultetu D. Savić-Pavićević je posle izbora u zvanje vanredni profesor iz naučnih aktivnosti ostvarila ukupno 277,2 boda (za redovnog profesora potrebno je ukupno 65 bodova), i to:- М10 + М20 + М30 + М40 + М50 + ostale naučne aktivnosti (član 9) = 276,2 boda (potrebno najmanje 50 bodova ), od toga iz kategorija М11, М12, М21а, М21, М22, М23, М31, rukovođenja evropskim okvirnim projaktima (FP), međunarodnim projaktima, nacionalnim projektima 175 bodova (potrebno najmanje 35 bodova)

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- М32, М34, М52, М61, М62, М63, М64, М66а, = 31,5 bodova (potrebno najmanje 6 bodova).

Zbir impakt faktora radova objavljenih posle izbora u vanrednog profesora iznosi 107,689.

ORCID http://orcid.org/0000-0002-2079-4077RESEARCHERID http://www.researcherid.com/rid/R-1255-2016

3.2. Osnovne naučne aktivnosti

M14 – Monografije, monografske studije, tematski zbornici, leksikografske i kartografske publikacije međunarodnog značaja


1. Nikolić Z, Savić Pavićević D, Brajušković G. Genetic Association Studies on Prostate Cancer. In: Mohan R, editor. Prostate Cancer - Leading-edge Diagnostic Procedures and Treatments. Rijeka: In Tech; 2016. p. 145-77. ISBN 978-953-51-2644-7. DOI: 10.5772/63280

2. Savić Pavićević D , Ivković M, Karanović J, Brajušković G, Romac S. Retinoic acid inducible-1 gene (RAI1) and clinical subtypes of schizophrenia. New York: NOVA Science Publisher; 2012. 28 p. ISBN 978-1-61942-471-5.

M21a – Rad u međunarodnom časopisu izuzetnih vrednosti Nakon izbora 2x10=20

Ukupno 2x10=20

3. Lohmann K, Masuho I, Patil DN, Baumann H, Hebert E, Steinrücke S, Trujillano D, Skamangas NK, Dobricic V, Hüning I, Gillessen-Kaesbach G, Westenberger A, Savic-Pavicevic D, Münchau A, Oprea G, Klein C, Rolfs A, Martemyanov KA. Novel GNB1 mutations disrupt assembly and function of G protein heterotrimers and cause global developmental delay in humans. Hum Mol Genet. 2017;26(6):1078-86.

DOI: 10.1093/hmg/ddx018Genetics & Heredity 16/166; Biochemistry & Molecular Biology 34/289 (2015)IF2015 5,985

4. Zimoń M, Baets J, Almeida-Souza L, De Vriendt E, Nikodinovic J, Parman Y, Battaloğlu E, Matur Z, Guergueltcheva V, Tournev I, Auer-Grumbach M, De Rijk P, Petersen BS, Müller T, Fransen E, Van Damme P, Löscher WN, Barišić N, Mitrovic Z, Previtali SC, Topaloğlu H, Bernert G, Beleza-Meireles A, Todorovic S, Savic-Pavicevic D, Ishpekova B, Lechner S, Peeters K, Ooms T, Hahn AF, Züchner S, Timmerman V, Van Dijck P, Rasic VM, Janecke AR, De Jonghe P, Jordanova A. Loss-of-function mutations in HINT1 cause axonal neuropathy with neuromyotonia. Nat Genet. 2012;44(10):1080-3.

DOI: 10.1038/ng.2406Genetics & Heredity 1/156 (2010)IF2010 36,377

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http://www.researcherid.com/rid/R-1255-2016

http://orcid.org/0000-0002-2079-4077

M21 – Rad u vrhunskom međunarodnom časopisuNakon izbora 10x8=80

Ukupno 16x8=128

5. Perić S, Nikodinović Glumac J, Töpf A, Savić-Pavicević D, Phillips L, Johnson K, Cassop-Thompson M, Xu L, Bertoli M, Lek M, MacArthur D, Brkušanin M, Milenković S, Milić Rašić V, Banko B, Maksimović R, Lochmüller H, Rakočević Stojanović V & Straub V. A novel recessive TTN founder variant is a common cause of distal myopathy in the Serbian population. Eur J Hum Genet. 2017;25(5):572-81.

DOI: 10.1038/ejhg.2017.16Genetics & Heredity 30/166; Biochemistry and Molecular Biology 60/289 (2015)IF2015 4,580

6. Karanović J, Ivković M, Jovanović VM, Pantović M, Pavlović Janković N, Damjanović A, Brajušković G, Romac S, Savić Pavićević D. Tryptophan hydroxylase 1 variant rs1800532 is associated with suicide attempt in Serbian psychiatric patients but does not moderate the effect of recent stressful life events. Suicide Life-Threat. Behav. 2016;46(6):664-8.

DOI: 10.1111/sltb.12246Psychiatry 51/200, Psychology Multidisciplinary 18/128 (2016)IF2016 3,252

7. Radovanović S, Perić S, Savić-Pavićević D, Dobričić V, Pešović J, Kostić V, Rakočević-Stojanović V. Comparison of temporal and stride characteristics in myotonic dystrophies type 1 and 2 during dual-task walking. Gait & Posture. 2016;44:194-9.

DOI: 10.1016/j.gaitpost.2015.12.020 Sport Sciences 12/81(2014)IF2014 2,752

8. Nikolić ZZ, Savić Pavićević DL, Vučic NL, Romac SP, Brajušković GN. Association between a Genetic Variant in the hsa-miR-146a Gene and Cancer Risk: An Updated Meta-Analysis. Public Health Genomics. 2015;18(5):283-98.

DOI: 10.1159/000438695Public, Environmental & Occupational Health 65/250 (2014)IF2014 2,208

9. Nikolić Z, Savić Pavićević D, Vučić N, Cidilko S, Filipović N, Cerović S,Vukotić V, Romac S, Brajušković G. Assessment of association between genetic variants in microRNA genes hsa-miR-499, hsa-miR-196a2 and hsa-miR-27a and prostate cancer risk in Serbian population. Exp Mol Pathol. 2015;99(1):145-50.

DOI: 10.1016/j.yexmp.2015.06.009Pathology 20/86 (2013)IF2013 2,881

10. Karanović J, Šviković S, Pantović M, Durica S, Brajušković G, Damjanović A, Jovanović V, Ivković M, Romac S, Savić Pavićević D. Joint effect of ADARB1 gene, HTR2C gene and stressful life events on suicide attempt risk in patients with major psychiatric disorders. World J Biol Psychiatry. 2015;16(4):261-71.

DOI: 10.3109/15622975.2014.1000374 Psychiatry 26/194 (2013)IF2013 4,225

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11. Sarajlija A, Kisic-Tepavcevic D, Nikolic Z, Savic Pavicevic D, Obradovic S, Djuric M, Pekmezovic T. Epidemiology of Rett syndrome in Serbia: prevalence, incidence and survival. Neuroepidemiology. 2015;44(1):1-5.

DOI: 10.1159/000369494Public, Environmental & Occupational Health 40/260 (2015)IF2015 2,784

12. Peric S, Mandic-Stojmenovic G, Stefanova E, Savic Pavicevic D, Pesovic J, Ilic V, Dobricic V, Basta I, Lavrnic D, Rakocevic-Stojanovic V. Frontostriatal dysexecutive syndrome: a core cognitive feature of myotonic dystrophy type 2. J Neurol. 2015;262(1):142-8.

DOI: 10.1007/s00415-014-7545-yClinical Neurology 37/193 (2013)IF2013 3,841

13. Nikolić ZZ, Savić Pavićević DLj, Vukotić VD, Tomović SM, Cerović SJ, Filipović N, Romac SP, Brajušković GN. Association between genetic variant in hsa-miR-146a gene and prostate cancer progression: evidence from Serbian population. Cancer Causes Control. 2014;25(11):1571-5.

DOI: 10.1007/s10552-014-0452-9Public, Environmental & Occupational Health 27/239 (2012)IF2012 3,200

14. Ivković M, Zamurović L, Jovanović A, Dobričić V, Damjanović A, Savić-Pavićević D, Romac S. Retinoic acid induced 1 gene and clinical subtypes of schizophrenia: an association study. Psychiatry Res. 2011;188(2):297-8.DOI: 10.1016/j.psychres.2010.11.018 Psychiatry 45/167 (2010)IF2010 2,803

***15. Kecmanović M, Ristić AJ, Sokić D, Keckarević-Marković M, Vojvodić N, Ercegovac M,

Janković S, Keckarević D, Savić Pavićević D, Romac S. Coexistence of Unverricht-Lundborg disease and congenital deafness: molecular resolution of a complex comorbidity. Epilepsia. 2009;50(6):1612-5.

DOI: 10.1111/j.1528-1167.2008.01937.xClinical Neurology 23/167 (2009)IF2009 4,052

16. Keckarević-Marković M, Milić-Rašić V, Mladenović J, Dačković J, Kecmanović M, Keckarević D, Savić Pavićević D, Romac S. Mutational analysis of GJB1, MPZ, PMP22, EGR2, and LITAF/SIMPLE in Serbian Charcot-Marie-Tooth patients. J Peripher Nerv Sys. 2009;4(2):125-36.


17. Stevanović M, Dobričić V, Keckarević D, Perović A, Savić-Pavicević D, Keckarević-Marković M, Jovanović A, Romac S. Human Y-specific STR haplotypes in population of Serbia and Montenegro. Forensic Sci Int. 2007;171(2-3):216-21.

DOI: 10.1016/j.forsciint.2006.05.038Medicine, Legal 2/9 (2007)IF2007 2,015

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18. Keckarević D, Savić D, Keckarević M, Stevanović M, Tarasjev A, Čuljković B, Đarmati A, Vukosavic S, Romac S. Population data on 14 STR loci from population of Serbia and Montenegro (new and renewed data). Forensic Sci Int. 2005;151(2-3):315-6.

DOI: 10.1016/j.forsciint.2005.01.009Medicine, Legal 2/9 (2005)IF2005 1,577

19. Čuljković B, Savić D, Stojković O, Romac S. Poly(A) tailing of ancient DNA: a method for reproducible microsatellite genotyping. Anal Biochem. 2003;318(1):124-31.

DOI: 10.1016/S0003-2697(03)00160-X Biochemical Research Methods 12/46 (2002)IF2002 2,370

20. Savić D , Rakočević-Stojanović V, Keckarević D, Čuljković B, Stojković O, Mladenović J, Todorović S, Apostolski S, Romac S. 250 CTG repeats in DMPK is a threshold for correlation of expansion size and age at onset of juvenile-adult DM1. Hum Mutat. 2002;19(2):131-9.

DOI: 10.1002/humu.10027 Genetics & Heredity 14/115 (2002)IF2002 6,894

M22 – Rad u istaknutom međunarodnom časopisuNakon izbora 12x5=60

Ukupno 24x5=120

21. Karanović J, Ivković M, Jovanović VM, Šviković S, Pantović-Stefanović M, Brkušanin M, Damjanović A, Brajušković G, Savić-Pavićević D. Effect of childhood general traumas on suicide attempt depends on TPH2 and ADARB1 variants in psychiatric patients. J Neural Transm. 2017;124(5):621-9.

DOI: 10.1007/s00702-017-1677-zJNT Neurosciences 139/256 (2015)IF2015 2,587

22. Vucic N, Nikolic Z, Vukotic V, Tomovic S, Vukovic I, Kanazir S, Savic-Pavicevic D, Brajuskovic G. NOS3 gene variants and male infertility: association of 4a/4b with oligoasthenozoospermia. Andrologia.

DOI: 10.1111/and.12817Andrology 3/5 (2016)IF2016 1,458

23. Nikolić Z, Savić Pavićević D, Vučić N, Cerović S, Vukotić V, Brajušković G. Genetic variants in RNA-induced silencing complex genes and prostate cancer. World J Urol. 2017; 35:613-24.

DOI: 10.1007/s00345-016-1917-0Urology & Nephrology 25/76 (2016)IF2016 2,743

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24. Rakocevic Stojanovic V, Peric S, Paunic T, Pesovic J, Vujnic M, Peric M, Nikolic A, Lavrnic D, Savic Pavicevic D. Quality of life in patients with myotonic dystrophy type 2. J Neurol Sci. 2016;365:158-61.

DOI: 10.1016/j.jns.2016.04.018 Clinical Neurology 82/192 (2014)IF2014 2,474

25. Rakocevic-Stojanovic V, Peric S, Savic-Pavicevic D, Pesovic J, Mesaros S, Lavrnic D, Jovanovic Z, Pavlovic A. Brain sonography insight into the midbrain in myotonic dystrophy type 2. Muscle Nerve. 2016;53(5):700-4.

DOI: 10.1002/mus.24927 Neurosciences 128/256 (2015) IF2015 2,713

26. Brkušanin M, Kosać A, Jovanović V, Pešović J, Brajušković G, Dimitrijević N,Todorović S, Romac S, Milić Rašić V, Savić-Pavićević D. Joint effect of the SMN2 and SERF1A genes on childhood-onset types of spinal muscular atrophy in Serbian patients. J Hum Genet. 2015;60(11):723-8.

DOI: 10.1038/jhg.2015.104Genetics & Heredity 84/165 (2015)IF2015 2,487

27. Nikolić ZZ, Pavićević DLj, Romac SP, Brajušković GN. Genetic Variants within Endothelial Nitric Oxide Synthase Gene and Prostate Cancer: A Meta-Analysis. Clin Transl Sci. 2015;8(1):23-31.

DOI: 10.1111/cts.12203Medicine, Research & Experimental 65/124 (2013)IF2013 2,110

28. Nikolić ZZ, Branković AS, Savić-Pavićević DL, Preković SM, Vukotić VD, Cerović SJ, Filipović NN, Tomović SM, Romac SP, Brajušković GN. Assessment of association between common variants at 17q12 and prostate cancer risk-evidence from Serbian population and meta-analysis. Clin Transl Sci. 2014;7(4):307-13.

DOI: 10.1111/cts.12130Medicine, Research & Experimental 60/121 (2012)IF2012 2,330

29. Branković AS, Brajušković GN, Mirčetić JD, Nikolić ZZ, Kalaba PB, Vukotić VD, Tomović SM, Cerović SJ, Radojičić ZA, Savić-Pavićević DL, Romac SP. Common variants at 8q24 are associated with prostate cancer risk in Serbian population. Pathol Oncol Res. 2013;19(3):559-69.

DOI: 10.1007/s12253-013-9617-1Pathology 45/76 (2013)IF2013 1,806

30. Branković A, Brajušković G, Nikolić Z, Vukotić V, Cerović S, Savić-Pavićević D, Romac S. Endothelial nitric oxide synthase gene polymorphisms and prostate cancer risk in Serbian population. Int J Exp Pathol. 2013;94(6):355-61.

DOI: 10.1111/iep.12045 Pathology 26/79 (2011)IF2011 2,556

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31. Nikolic A, Rakocevic Stojanovic V, Romac S, Savic D, Basta I, Lavrnic D. The coexistence of myasthenia gravis and myotonic dystrophy type 2 in a single patient. J Clin Neurol. 2013;9(2):130-2.

DOI: 10.3988/jcn.2013.9.2.130Clinical Neurology 108/192 (2012)IF2012 1,892

32. Savić Pavićević D , Miladinović J, Brkušanin M, Šviković S, Djurica S, Brajušković G, Romac S. Molecular genetics and genetic testing in myotonic dystrophy type 1. Biomed Res Int. 2013;2013:391821.

DOI: 10.1155/2013/391821Medicine, Research & Experimental 46/121, Biotechnology & Applied Microbiology 50/160 (2012)IF2012 2,880

***33. Šarić M, Zamurović Lj, Keckarević-Marković M, Keckarević D, Stevanović M, Savić

Pavicević D, Jović J, Romac S. Frequency of the hemochromatosis gene mutations in the population of Serbia and Montenegro. Clin Genet. 2006;70(2):170-2.

DOI: 10.1111/j.1399-0004.2006.00655.x Genetics & Heredity 45/124 (2005)IF2005 3,276

34. Mladenović J, Pekmezović T, Todorović S, Rakočević-Stojanović V, Savić D, Romac S, Apostolski S. Survival and mortality of myotonic dystrophy type 1 (Steinert's disease) in the population of Belgrade. Eur J Neurol. 2006;13(5):451-4.

DOI: 10.1111/j.1468-1331.2006.01261.xNeurosciences 100/199, Clinical Neurology 47/145 (2006)IF2006 2,437

35. Mladenović J, Pekmezović T, Todorović S, Rakočević-Stojanović V, Savić D, Romac S, Apostolski S. Epidemiology of myotonic dystrophy type 1 (Steinert disease) in Belgrade (Serbia). Clin Neurol Neurosurg. 2006;108(8):757-60.

DOI: 10.1016/j.clineuro.2006.04.004Clinical Neurology 85/145 (2006)IF2006 1,506

36. Krndija D, Savić D, Mladenović J, Rakočević-Stojanović V, Apostolski S, Todorović S, Romac S. Haplotype analysis of the DM1 locus in the Serbian population. Acta Neurol Scand. 2005;111(4):274-7.


37. Rakočević-Stojanović V, Savić D, Pavlović S, Lavrnić D, Stević Z, Basta I, Romac S, Apostolski S. Intergenerational changes of CTG repeat depending on the sex of the transmitting parent in myotonic dystrophy type 1. Eur J Neurol. 2005;12(3):236-7.

DOI: 10.1111/j.1468-1331.2004.01075.x Neurosciences 105/200, Clinical Neurology 56/147 (2005)IF2005 2,244

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38. Alendar A, Čuljković B, Savić D, Đarmati A, Keckarević M, Ristić A, Dragašević N, Kostić V, Romac S. Spinocerebellar ataxia type 17 in the Yugoslav population. Acta Neurol Scand. 2004;109(3):185-7.

DOI: 10.1034/j.1600-0404.2003.00196.x Clinical Neurology 61/140 (2004)IF2004 1,712

39. Svetel M, Đarmati A, Dragašević N, Savić D, Čuljkovic B, Romac S, Kostić VS. SCA2 and SCA3 mutations in young-onset dopa-responsive parkinsonism. Eur J Neurol. 2003;10(5):597.

DOI: 10.1046/j.1468- 1331.2003.00671.x Neurosciences 105/198, Clinical Neurology 51/135 (2003)IF2003 2,000

40. Topisirović I, Dragašević N, Savić D, Ristić A, Keckarević M, Keckarević D, Čuljković B, Petrović I, Romac S, Kostić VS. Genetic and clinical analysis of spinocerebellar ataxia type 8 repeat expansion in Yugoslavia. Clin Genet. 2002;62(4):321-4.

DOI: 10.1034/j.1399-0004.2002.620412.x Genetics & Heredity 50/113 (2001)IF2001 2,395

41. Čuljković B, Stojković O, Vukosavić S, Savić D, Rakočević V, Apostolski S, Romac S. CTG repeat polymorphism in DMPK gene in healthy Yugoslav population. Acta Neurol Scand. 2002;105(1):55-8.

DOI: 10.1034/j.1600-0404.2002.00006.x Clinical Neurology 70/138 (2002)IF2002 1,358

42. Savić D , Topisirović I, Keckarević M, Keckarević D, Major T, Čuljković B, Stojković O, Rakočević-Stojanović V, Mladenović J, Todorović S, Apostolski S, Romac S. Is the 31 CAG repeat allele of the spinocerebellar ataxia 1 (SCA1) gene locus non-specifically associated with trinucleotide expansion diseases? Psychiatr Genet. 2001;11(4):201-5.

DOI: 10.1097/00041444-200112000-00004 Genetics & Heredity 39/114, Neurosciences 65/203 (2000)IF2000 2,609

43. Keckarević D, Čuljković B, Savić D, Stojković O, Kostić V, Vukosavić S, Romac S. The status of SCA1, MJD/SCA3, FRDA, DRPLA and MD triplet containing genes in patients with Huntington disease and healthy controls. J Neurogenet. 2000;14(4):257-63.

DOI: 10.3109/01677060009084502 Genetics & Heredity 59/114, Neurosciences 95/203 (2000)IF2000 1,938

44. Čuljković B, Stojković O, Savić D, Zamurović N, Nešić M, Major T, Keckarević D, Romac S, Zamurović B, Vukosavić S. Comparison of the number of triplets in SCA1, MJD/SCA3, HD, SBMA, DRPLA, MD, FRAXA and FRDA genes in schizophrenic patients and a healthy population. Am J Med Genet B Neuropsychiatr Genet. 2000;96(6):884-7.

DOI: 10.1002/1096-8628(20001204)96:6<884::AID-AJMG41>3.0.CO;2-MGenetics & Heredity 42/114 (2000)IF2000 2,479

24

M23 – Rad u međunarodnom časopisu Nakon izbora 5x3=15

Ukupno 13x3=39

45. Peric S, Rakocevic Stojanovic V, Mandic Stojmenovic G, Ilic V, Kovacevic M, Parojcic A, Pesovic J, Mijajlovic M, Savic-Pavicevic D, Meola G. Clusters of cognitive impairment among different phenotypes of myotonic dystrophy type 1 and type 2. Neurol Sci. 2017;38(3):415-423.

DOI: 10.1007/s10072-016-2778-4Neurosciences 189/256, Clinical neurology 127/193 (2015)IF2015 1,783

46. Milic Rasic V, Vojinovic D, Pesovic J, Mijalkovic G, Lukic V, Mladenovic J, Kosac A, Novakovic I, Maksimovic N, Romac S, Todorovic S, Savic Pavicevic D. Intellectual ability in the duchenne muscular dystrophy and dystrophin gene mutation location. Balkan J Med Genet. 2015;17(2):25-35.

DOI: 10.2478/bjmg-2014-0071 Genetics & Heredity 159/167 (2014)IF2014 0,500

47. Nikolić ZZ, Brajušković GN, Pavićević DLj, Kojić AS, Vukotić VD, Tomović SM, Cerović SJ, Filipović V, Mišljenović D, Romac SP. Assessment of possible association between rs3787016 and prostate cancer risk in Serbian population. Int J Clin Exp Med. 2013;6(1):57-66.

PMID: 23236559Medicine, Research & Experimental 87/124 (2013)IF2013 1,422

48. Brajuskovic GN, Nikolic ZZ, Kojic AS, Savic-Pavicevic DLJ, Cerovic SJ, Tomovic SM, Filipovic NN, Vukotic VD, Romac SP. Assessment of Possible Association Between Rs378854 and Prostate Cancer Risk in the Serbian Population. Arch Biol Sci. 2013;65(2):475-86.

Biology 60/82 (2012)IF2012 0,791

49. Brajušković G, Savić Pavićević D, Romac S. 60th Anniversary of the DNA Secondary Structure Discovery. Vojnosanit Pregl. 2013;70(12):1165-70.

PMID: 24450265Medicine, General & Internal 139/156 (2013)IF2013 0,269

***50. Kecmanović M, Dobričić V, Dimitrijević R, Keckarević D, Savić Pavićević D,

Keckarević-Marković M, Ivković M, Romac S. Schizophrenia and apolipoprotein E gene polymorphisms in Serbian population. Int J Neurosci. 2010;120(7):502-6.

DOI: 10.3109/00207451003765956Neurosciences 187/221 (2008)IF2008 0,884

25

51. Dimitrijević R, Čadež I, Keckarević-Marković M, Keckarević D, Kecmanović M, Dobričić V, Savić Pavićević D, Brajušković G, Romac S. Polymorphisms of the prion protein gene (PRNP) in a Serbian population. Int J Neurosci. 2010;120(7):496-501.


52. Šijačić-Nikolić M, Milovanović J, Bobinac M, Savić Pavićević D, Brajušković G, Diklić M. Variability Of The Chloroplast Dna Of Sessile Oak (Quercus petraea Agg. Ehrendorfer, 1967) in Serbia. Arch Biol Sci. 2009;61(3):459-65.

Biology 73/76 (2009)IF2009 0,238

53. Janković N, Kecmanović M, Dimitrijević R, Keckarević Marković M, Dobricić V, Keckarević D, Savić Pavicević D, Romac S. HD phenocopies - possible role of Saitohin gene. Int J Neurosci. 2008;118(3):391-7.


54. Savić D , Keckarević D, Branković-Srećković V, Apostolski S, Todorović S, Romac S. Clinical case report atypical myopathy in a young girl with 91 CTG repeats in DM1 locus and a positive DM1 family history. Int J Neurosci. 2006;116(12):1509-18.


55. Keckarević M, Savić D, Romac S. JP-3 gene polymorphism in a healthy population of Serbia and Montenegro. J Genet. 2005;84(1):69-71.

DOI: 10.1007/BF02715892Genetics & Heredity 97/120 (2004)IF2004 1,100

56. Keckarević M, Savić D, Svetel M, Kostić V, Vukosavić S, Romac S. Yugoslav HD phenocopies analyzed on the presence of mutations in PrP, ferritin, and Jp-3 genes. Int J Neurosci. 2005;115(2):299-301.


57. Romac S, Čuljković B, Vukosavić S, Stojković O, Savić D, Keckarević D, Zamurović N, Major T, Keckarević M, Topisirović I. Dynamic mutations as a cause of hereditary neurological and psychiatric diseases. Yugoslav Med Biochem (J Med Biochem). 2001;20(1):1-7.

Biochemistry and Molecular Biology IF2001 0,116

26

М24 – Rad u časopisu međunarodnog značaja verifikovanog posebnom odlukom Nakon izbora 0

Ukupno1x2=2***

58. Keckarević M, Savić D, Čuljković B, Zamurović N, Major T, Keckarević D, Todorović S, Romac S. Duchenne's and Becker's muscular dystrophy: analysis of phenotype-genotype correlation in 28 patients. Srp Arh Celok Lek. 2002;130(5-6):154-8.

DOI: 10.2298/sarh0206154k

Rad u međunarodnom časopisu bez kategorije indeksiran u bazi PubMedNakon izbora 0x2=0

Ukupno 0x5=0

59. Rakocevic-Stojanovic V, Peric S, Dujmovic I, Drulovic J, Pesovic J, Savic-Pavicevic D. Neuromyelitis Optica in a Patient from Family with both Myotonic Dystrophy Type 1 and 2. J Neuromuscul Dis. 2017; 4(1):89-92.

DOI:10.3233/JND-160192PMID: 28106565

60. Peric M, Peric S, Rapajic N, Dobricic V, Savic-Pavicevic D, Nesic I, Radojicic S, Novakovic I, Lavrnic D, Rakocevic-Stojanovic V. Multidimensional aspects of pain in myotonic dystrophies. Acta Myol. 2015;34(2-3):126-32.

PMID: 27199540***

61. Rakočević-Stojanović V, Savić D, Romac S, Apostolski S. Genetic study of somatic mosaicism in a patient with myotonic dystrophy type 1: case report. Acta Myol. 2003;22(3):104-5.

PMID: 15088500

62. Rakočević-Stojanović V, Savić D, Pavlović S, Lavrnić D, Romac S, Apostolski S. Correlation between cardiac involvement and CTG repeat amplification in myotonic dystrophy type 1. Acta Myol. 2003;22(1):26-7.

PMID: 12966702

63. Rakočević-Stojanović V, Pavlović S, Lavrinić D, Trikić R, Savić D, Romac S, Dožić S, Apostolski S. Peripheral neuropathy in patients with myotonic dystrophy. Acta Myol. 2002;21:36-7.

M34 – Saopštenje sa međunarodnog skupa štampano u izvoduNakon izbora 40x0,5=20

Ukupno 54x0,5=27

64. Kovacevic G, Todorovic S, Novakovic I, Savic Pavicevic D, Milic Rasic V, Svetel M, Dobricic V. Genotype-phenotype correlation in Friedreich's ataxia. In: European Journal of Paediatric Neurology, 2017, vol. 21, suppl. 1. Abstracts of EPNS 2017 - 12th European Paediatric Neurology Society Congress; June 20- 24 2017; Lyon, France. e205-6, P3-66.

65. Brkušanin M, Kosać A, Jovanović V, Pešović J, Brajušković G, Milić Rašić V, Savić-Pavićević D. SMN2 gene copy number and promoter methylation as disease modifiers of childhood-onset spinal muscular atrophy. In: Book of Abstracts of European

27

Network to Cure ALS (ENCALS) Meeting 2017; 2017 May 18-20; Ljubljana, Slovenia. p. 61, P60.

66. Karanović J, Ivković M, Jovanović V, Pantović Stefanović M, Brkušanin M, Damjanović A, Brajušković G, Savić Pavićević D. Effect of childhood general traumas on suicde attempt depends on TPH2 and ADARB1 variants in psychiatric patients. In: Psihijat dan, 2016, suppl./48/1/5-145. XV Congress of Serbian Psychiatric Association and Regional Congress of Psychiatric Association for Eastern Europe and the Balkans: Pathways and Crossroads of Psychiatry; 2016 October 12-15; Belgrade, Serbia. p. 80, P30.

67. Savić-Pavićević D , Brajušković G. Coevolution of the repeated glutamine and proline codons in the mammalian Huntington disease gene. In: Abstract Book of the 2nd NGP-NET Symposium; 2016 September 15-17; Belgrade, Serbia. P25.

68. Rakocevic Stojanovic VM, Peric S, Ilic V, Parojcic A, Pesovic J, Savic-Pavicevic D, Brajkovic L. 18F-FDG-PET Study in patients with myotonic dystrophy type 1 and 2. In: Journal of Neuromuscular Diseases, 2016, vol. 3, no. s1. 14th International Congress on Neuromuscular Diseases; 2016 July 5-9; Toronto, Canada. p. S167.

69. Peric SZ, Mandic-Stojmenovic G, Ilic V, Kovacevic M, Parojcic A, Dobricic V, Pesovic J, Novakovic I, Savic-Pavicevic D, Rakocevic-Stojanovic V. Clusters of cognitive impairment among different forms of myotonic dystrophies. In: European Journal of Neurology, 2016, vol. 23, suppl 1. 2nd Congress of the European Academy of Neurology; 2016 May 28-31; Copenhagen, Denmark. p. 573, P22128.

70. Vujnic M, Peric SZ, Paunic T, Pesovic J, Perić M, Lavrnic D, Savic-Pavicevic D, Rakocevic Stojanovic V. Myotonic dystrophy type 2 significantly affects quality of life. In: European Journal of Neurology, 2016, vol. 23, suppl 1. 2nd Congress of the European Academy of Neurology; 2016 May 28-31; Copenhagen, Denmark. p. 863, P32167

71. Nikodinovic Glumac J, Topf A, Lochmüller H, Savic-Pavicevic D, Bertoli M, Lek M, MacArthur DG, Xu L, Peric S, Milic Rasic V, Brkusanin M, Milenković S, Cassop-Thompson MJ, Banko B, Maksimovic R, Rakocevic Stojanovic V, Straub V. A novel recessive TTN founder mutation is causing a distal myopathy phenotype in a Serbian patient cohort. In: Program and Abstracts of the Conference on Structure and Dynamics of the Sarcomere; 2016 May 4-6; Belgrade, Serbia. p. 57-58, P13.

72. Peric S, Rakocevic Stojanovic V, Nikodinovic Glumac J, Topf A, Lochmüller H, Savic-Pavicevic D, Bertoli M, Lek M, MacArthur DG, Xu L, Milic Rasic V, Brkusanin M, Milenković S, Cassop-Thompson MJ, Straub V. Phenotypic characteristics of titinopathy caused by a founder autosomal recessive mutation in Serbian population. In: Program and Abstracts of the Conference on Structure and Dynamics of the Sarcomere; 2016 May 4-6; Belgrade, Serbia. p. 60-61, P15.

73. Peric S, Nikodinovic Glumac J, Topf A, Lochmüller H, Bertoli M, MacArthur D, Lek M, Xu L, Savic Pavicevic D, Milenkovic S, Cassop-Thompson M, Milic Rasic V, Rakocevic Stojanovic V, Straub V. A recessive TTN founder mutation is causing a distal myopathy phenotype in a Serbian patient cohort. In: Book of Apstracts AFM-Téléthon of the 5th International Congress of Myology; 2016 March 14-18; Lyon, France. p. 69-70, P07-99.

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74. Brkušanin M, Kosać A, Jovanović V, Pešović J, Brajušković G, Dimitrijević N, Todorović S, Romac S, Milic Rašić V, Savić Pavićević D. Joint effect of the SMN2 and SERF1A genes on early-onset Serbian spinal muscular atrophy patients. In: Book of abstracts of the 11th Balkan Congress of Human Genetics; 2015 September 17-20; Belgrade, Serbia. p. 38-9.

75. Karanović J, Šviković S, Pantović M, Djurica S, Brajušković G, Damjanović A, Jovanović V, Ivković M, Romac S, Savić Pavićević D. Association of HTR2C gene with suicide attempt risk in Serbian patients with major psychiatric disorders. In: Book of abstracts of the 11th Balkan Congress of Human Genetics; 2015 September 17-20; Belgrade, Serbia. p. 58-9.

76. Nikolić Z, Savić Pavićević D, Vučić N, Cidilko S, Vukotić V, Filipović N, Romac S, Brajušković G. Assessment of association between rs496128 located in AGO2 gene and prostate cancer risk in Serbian population. In: Book of abstracts of the 11th Balkan Congress of Human Genetics; 2015 September 17-20; Belgrade, Serbia. p. 38.

77. Pešović J, Rakočević Stojanović V, Perić S, Brkušanin M, Brajušković G, Romac S, Savić Pavićević D. Variant repeats in DM1 patients might be associated with milder clinical presentation. In: Programme & Abstracts of the 10thInternational Myotonic Dystrophy Consortium Meeting (IDMC); 2015 June 8-12; Paris, France. p.102.

78. Kovčić V, Perić S, Pešović J, Brkušanin M, Brajušković G, Romac S, Ranum L, Rakočevič Stojanović V, Savić Pavićević D. European founder haplotypes in Serbian patients with myotonic dystrophy type 2. In: Programme & Abstracts of the 10th International Myotonic Dystrophy Consortium Meeting (IDMC); 2015 June 8-12; Paris, France. p. 105.

79. Rakočević-Stojanović V, Perić S, Pešović J, Dujmović Basuroski I, Jovanović D, Nikolić A, Savić Pavićević D. Neuromyelitis optica in family with both myotonic dystrophy type 1 and type 2 mutations. In: Programme & Abstracts of the 10th International Myotonic Dystrophy Consortium Meeting (IDMC); 2015 June 8-12; Paris, France. p. 147.

80. Karanović J, Šviković S, Pantović M, Durica S, Brajušković G, Damjanović A, Jovanović V, Ivković M, Romac S, Savić Pavićević D. Association of ADARB1 gene with suicide attempt risk in patients with major psychiatric disorders. In: European Journal of Human Genetics, 2015,vol. 23, suppl. 1. European Conference of Human Genetics 2015; 2015 June 6-9; Glasgow, Scotland, UK. p. 414.

81. M. Brkušanin, Kosać A, Jovanović V, Pešović J, Brajušković G, Dimitrijević N, Romac S, Milić Rašić V, Savić Pavićević D. Correlation of copy number of the SMN2, SERF1A and NAIP genes with severity of spinal muscular atrophy in Serbian patients. In: European Journal of Human Genetics, 2015, vol. 23, suppl. 1. European Conference of Human Genetics 2015; 2015 June 6-9; Glasgow, Scotland, UK. p. J10.11.

82. Nikolić Z, Savić Pavićević D, Vučić N, Cidilko S, Vukotic V, Filipović N, Romac S, Brajušković G. Analysis of potential association between genetic variants in microRNA genes hsa-miR-499 and hsa-miR-196a2 and prostate cancer risk in Serbian population. In: European Journal of Human Genetics, 2015, vol. 23, suppl. 1. European Conference of Human Genetics 2015; 2015 June 6-9; Glasgow, Scotland, UK. p. J18.23.

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83. Milic Rasic V, Brankovic V, Mladenovic J, Nikodinovic J, Kosac A, Baets J, De Jonghe P, Jordanova A, Zimon M, Keckarevic Markovic M, Pavicevic Savic D, Todorovic S. Is it easy to recognize HINT1 neuropathy? In: European Journal of Paediatric Neurology, 2015, vol. 19, suppl. 1. Abstracts of the 11th European Paediatric Neurology Society Congress; 2015 May 27-30; Vienna, Austria. PP09.9-2907.

84. Pesovic J, Rakocevic Stojanovic V, Peric S, Brajuskovic G, Romac S , Savic Pavicevic D. Variant repeats as genetic modifiers of DM1 – a case report. In: SNC15 Book of Abstracts of the SiNAPSA Neuroscience Conference'15 (SNC'15); 2015 May 15-17; Ljubljana, Slovenija. p. 67.

85. Nikolić Z, Savić Pavićević D, Vučić N, Vukotić V, Tomović S, Cerović S, Filipović N, Romac S, Brajušković G. Assessment of association between genetic variant in hsa-miR-146a gene and prostate cancer risk in Serbian population. In: European Urology Supplements 2014, vol. 13, no. 5. 6th European Multidisciplinary Meeting on Urological Cancers (EMUC) and 3rd Meeting of the EAU Section of Urological Imaging (ESUI); 2014 November 13-16; Lisbon, Portugal. p. 127.

86. Kojić S, Milić Rašić V, Mladenović J, Kosac A, Vojinović D, Nikodinović Glumac J, Rakočević Stojanović V, Lavrnić D, Stević Z, Basta I, Marjanović I, Perić S, Nikolić A, Novaković I, Milenković S, Brkušanin M, Pešović J, Savić Pavićević D, Romac S, Radojković D, Nestorović A, Jasnić-Savović J. Diagnosis of neuromuscular diseases in Serbia and launch of Serbian Neuromuscular Disease Network NMD-SERBNET. In: Program and Abstracts of the Symposium Genomics of Rare Diseases Serbordisinn & 2014 Golden Helix Symposium; 2014 October 31-November 1; Belgrade, Serbia. p. 49.

87. Pesovic J, Peric S, Brkusanin M, Mandic M, Brajuskovic G, Romac S, Rakocevic-Stojanovic V, Savic Pavicevic D. PCR based Southern blot method for detection of expansions associated with myotonic dystrophy type 2. Symposium Genomics of Rare Diseases Serbordisinn & 2014 Golden Helix Symposium; 2014 October 31-November 1; Belgrade, Serbia.

88. Nikolić Z, Savić Pavićević D, Vučić N, Vukotić N, Tomović S, Cerović S, Filipović N, Romac S, Brajušković G. Assessment of association between genetic variant rs7813 in GEMIN4 and prostate cancer risk in Serbian population. In: European Urology Supplements 2014, vol. 13, no. 7. EAU 10th South Eastern European Meeting (SEEM); 2014, October 24-26; Belgrade, Serbia. p. e1505.

89. Vučić N, Nikolić Z, Savić Pavićević D, Kanazir S, Vukotić V, Romac S, Brajušković G. Assessment of possible association between genetic variant rs895819 in miR-27a gene and infertility in males diagnosed with non-obstructive azoospermia (NOA) from Serbian population. In: European Urology Supplements 2014, vol. 13, no. 7. EAU 10th South Eastern European Meeting (SEEM); 2014, October 24-26; Belgrade, Serbia. p. e1475.

90. Perić S, Stefanova E, Savić Pavićević D, Dobričić V, Ralić V, Pešović J, Novaković I, Rakočević Stojanović V. Executive function and visual memory computerized testing in myotonic dystrophies. In: Journal of Neuromuscular Diseases 2014, vol.1, suppl. 1. 13th International Congress on Neuromuscular Diseases (ICNMD XIII). 2014 July 5-10; Nice, France. p. S147-8.

91. Rakočević Stojanović V, Perić S, Savić Pavićević D, Pešović J, Pavlović A. Transcranial sonography in patients with myotonic dystrophy type 2. In: Journal of Neuromuscular Diseases 2014, vol.1, suppl. 1. 13th International Congress on Neuromuscular Diseases (ICNMD XIII). 2014 July 5-10; Nice, France. p. S148

30

92. Perić M, Perić S, Dobričić V, Savić Pavićević D, Ralić V, Pešović J, Novaković I, Rakočević Stojanović V. Assessment of pain in myotonic dystrophies. In: Journal of Neuromuscular Diseases 2014, vol.1, suppl. 1. 13th International Congress on Neuromuscular Diseases (ICNMD XIII). 2014 July 5-10; Nice, France. p. S148-9.

93. Perić S, Savić Pavićević D, Pešović J, Nikolić A, Kacar A, Perić M, Marjanović I, Lavrnić D, Rakočević Stojanović V. Phenotypic variability of myotonic dystrophy type 2. In: European Journal of Neurology 2014, vol. 21, suppl. 1. Joint Congress of European Neurology; 2014 May 31-June 3; Istanbul, Turkey. p. 527.

94. Vojinovic D, Pesovic J, Savic-Pavicevic D, Milic-Rasic V, Mijalkovic G, Lukic V, Mladenovic J, Maksimovic N, Todorovic S. Intellectual ability in Duchenne muscular dystrophy and dystrophin gene mutation location. In: European Journal of Neurology 2014, vol. 21, suppl. 1. Joint Congress of European Neurology; 2014 May 31-June 3; Istanbul, Turkey. p. 255.

95. Perić S, Savić Pavićević D, Pešović J, Nikolić A, Basta I, Lavrnić D, Rakočević Stojanović V. Clinical findings in myotonic dystrophy type 1 vs. type 2 – a comparative study. In: Acta Clinica Croatica 2014,vol. 53, suppl. 1. 54th International Neuropsychiatric Pula Congress; 2014 June 18-21; Pula, Croatia. p. 96.

96. Đurica S, Miladinović J, Pantović M, Ivin M, Šviković S, Brajušković G, Ivković M, Savić Pavićević D. Association of ADARB1 gene with major psychiatric dieorders. In: European Journal of Human Genetics 2013, vol. 21, suppl. 2. European Human Genetics Conference 2013; 2013 June 8-11; Paris, France. p. 198.

97. Nikolić Z, Brajušković G, Vukotić V, Filipović N, Cerović S, Savić Pavićević D, Romac S. Epistatic interactions between prostate cancer susceptibility loci: evidence from Serbian population. In: European Journal of Human Genetics 2013, vol. 21, suppl. 2. European Human Genetics Conference 2013; 2013 June 8-11; Paris, France. p. 316.

98. Nikolić Z, Brajušković G, Savić Pavićević D, Kojić A, Vukotić V, Tomović S, Cerović S, Romac S. Analysis of association between single nucleotide genetic variant rs3787016 and prostate cancer risk in Serbian population. In: European Urology Supplements 2012, vol. 11, no. 4. EAU 8th South Eastern European Meeting (SEEM); 2012, October 26-27; Sofia, Bulgaria. p. 143.

99. Kojić A, Brajušković G, Savić Pavićević D, Nikolić Z, Vukotić V, Tomović S, Vuković I, Cerović S, Romac S. Analysis of association between single nucleotide genetic variant rs378854 and prostate cancer risk in Serbian population. In: European Urology Supplements 2012, vol. 11, no. 5. 4th European Multidisciplinary Meeting on Urological Cancers (EMUC): Embracing Excellence in Treatment of Prostate, Bladder and Kidney Cancer; 2012 November 16-18; Barcelona, Spain. p. 224-5.

100. Šviković S, Brkušanin M, Karanović J, Pantović M, Đurica S, Brajušković G, Romac S, Ivković M, Savić Pavićević D. From genotype to phenotype: in silico modelling of serotonergic system. In: Book of Abstracts of the Theoretical Approaches to BioInforamtion Systems TABIS 2013; 2013 September 17-22; Belgrade, Serbia. p. 31.

101. Brajusković G, Mirković M, Stanković I, Savić Pavićević D, Branković A, Cerović S, Tomović S, Vukotić V, Romac S. Analysis of two single nucleotide polymorphisms at locus 17q12 associated with prostate cancer in Serbian population. In: European Urology Supplements 2011, vol. 10, no. 9. EAU 11th Central European Meeting (CEM); 2011 October 28-29; Timisoara, Romania. p. 614.

31

102. Brajušković G, Branković A, Savić Pavićević D, Mirčetić J, Cerović S, Tomović S, Vuković I, Vukotić V, Romac S. Correlation between polymorphisms at promoter region of the NOS3 gene and prostate cancer in Serbian population. In: Virchows Archiv, 2011, vol. 459, suppl. 1. 23rd European Congress of Pathology; 2011 August 27-September 1; Helsinki, Finland. p. S319.

103. Brajušković G, Mirčetić J, Savić Pavićević D, Cerović S, Tomović S, Jeremić N, Vuković I, Vukotić V, Romac S. Analysis of five single nucleotide polymorphisms at locus 8q24 associated with prostate cancer in Serbian population. In: Virchows Archiv, 2011, vol. 459, suppl. 1. 23rd European Congress of Pathology; 2011 August 27-September 1; Helsinki, Finland. p. S319.

***104. Savić Pavićević D , Krndija D, Brajušković G, Romac S. Coevolution of the repeated

glutamine and proline codons in the mammalian Huntington disease gene. In: Europen Journal of Human Genetics, 2009, vol. 17, suppl. 2. European Human Genetics Conference 2009; 2009 May 23-26; Vienna, Austria. p. 271, P10.043.

105. Šarić M, Zamurović Lj, Keckarević-Marković M, Keckarević D, Kecamnović M, Savić Pavićević D, Jović J, Romac S. Frequency of the hemochromatosis gene mutations in patients with hereditary hemochromatosis and in control subjects from Serbia. In: Europen Journal of Human Genetics, 2008, vol. 16, suppl. 2. European Human Genetics Conference 2008; 2008 May 31-June 03; Barcelona, Spain. p. 379, P07.066.

106. Keckarević-Marković M, Milić-Rašić V, Dobričić V, Kecmanović M, Dimitrijević R, Šarić M, Savić Pavićević D, Keckarević D, Todorović S, Romac S. Hereditary Motor and Sensory Neuropathy type Lom in Serbian Romani family. In: Journal of Neurology, 2007, vol. 254, suppl 3. 17th Meeting of the European Neurological Society; 2007 June 16-20; Rhodes, Greece. p. III/109, P432.

107. Kecmanović M, Ercegovac M, Dimitrijević R, Dobričić V, Keckarević-Marković M, Savić Pavicević D, Šarić M, Keckarević D, Beslać-Bumbaširević Lj, Romac S. Unverricht-Lundborg disease: the first report of genetically confirmed case in Serbia. In: Journal of Neurology, 2007, vol. 254, suppl 3. 17th Meeting of the European Neurological Society. 2007 June 16-20; Rhodes, Greece. p. III/125, P497.

108. Dobričić V, Keckarević-Marković M, Stevanović M, Šarić M, Savić D, Keckarević D, Romac S. Friedreich’s ataxia: analysis of mitotic instability. In: Final Program and Abstracts of the 4th European-American School in Forensic Genetics and Mayo Clinic Course in advanced Molecular and Cellular Medicine; 2005 September 5-9; Dubrovnik, Croatia. p.117, M10.

109. Keckarević-Marković M, Dobričić V, Stevanović M, Šarić M, Savić D, Keckarević D, Romac S. Linkage analysis by microsatellite repeats on a Duchenne muscular dystrophy family: a case report. In: Final Program and Abstracts of the 4th European-American School in Forensic Genetics and Mayo Clinic Course in advanced Molecular and Cellular Medicine; 2005 September 5-9; Dubrovnik, Croatia. p.127, M20.

110. Stojanović V, Savić D, Pavlović S, Lavrnić D, Stević Z, Basta I, Vujić A, Romac S, Apostolski S. Clinical and genetic study of myotonic dystrophy type 1 in Serbian population. In: Journal of Neurology, 2004, vol. 251, suppl 3. 14th Meeting of the European Neurological Society; 2004 June 26-30, Barcelona, Spain. p. 174, P680.

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111. Rakočević-Stojanović V, Savić D, Pavlović S, Lavrinić D, Stević Z, Basta I, Vujić A, Romac S, Apostolski S. Characteristic of intergenerational changes of CTG repeat in myotonic dystrophy type 1. In: Book of Abstracts of the 35th International Danube Symposium for Neurological Sciences and Continuing Education; 2003 September 11-14; Belgrade, Serbia and Montenegro. p.132, P76.

112. Rakočević-Stojanović V, Savić D, Lavrinić D, Vujić A, Pavlović S, Romac S, Apostolski S. Genotype-phenotype correlation in myotonic dystrophy type 1. In: European Journal of Neurology, 2003, vol. 10, suppl. 1. 7th Congress of the European Federation of Neurological Societies; 2003 August 30-September 2; Helsinki, Finland. p. 40, SC328.

113. Rakočević-Stojanović V, Savić D, Pavlović S, Lavrinić D, Romac S, Apostolski S. The role of parent’s sex in intergenerational changes of CTG repeats in patients with myotonic dystrophy type 1. In: Journal of Neurololgy, 2003, vol. 250, suppl. 2. 13th meeting of the European Neurological Society; 2003 June 14-18; Istanbul, Turkey. p. II/204, P791.

114. Rakočević-Stojanović V, Savić D, Keckaravić D, Keckarević M, Romac S, Apostolski S. SP/LR PCR and non-radioactive hybridization for prenatal diagnosis of myotonic dystrophy type 1 – case report. In: Journal of Neurological Sciences, 2002, vol. 199. 10th International Congress on Neuromuscular Diseases; 2002 July 7-12; Vancouver, Canada. p. S108, P677.

115. Rakočević-Stojanović V, Savić D, Pavlović S, Romac S, Apostolski S. Reduction in size of the myotonic dystrophy trinucleotide repeat mutation during transmition. In: European Journal of Neurology, 2002, vol. 9, suppl. 2. 6th Congress of the European Federation of Neurological Societies; 2002 October 26-29; Vienna, Austria. p. 25, SC138.

116. Rakočević-Stojanović V, Savić D, Pavlović S, Lavrinić D, Grujić M, Romac S, Apostolski S. Correlation between cardiac involvement and CTG repeat amplification in myotonic dystrophy type 1. In: Journal of Neurology, 2002, vol. 249, suppl. 1. 12th meeting of the European Neurological Society; 2002 June 22-26; Berlin, Germany. p. 1/89, P331.

117. Savić D , Keckarević D, Topisirović I, Keckarević M, Major T, Čuljković B, Stojković O, Vukosavić S, Romac S. Is the 31 CAG repeat allele of the spinocerebellar ataxia 1 (SCA1) gene locus non-specificaly associated with trinucleotide expansion diseases? Molecular Mechanisms of Polyglutamine diseases; 2002 May 23-25; Bonn, Germany.

M45 – Poglavlje u knjizi M42 ili rad u tematskom zborniku nacionalnog značaja

Nakon izbora 1x1,5=1,5Ukupno 2x1,5=3

118. Savić-Pavićević D , Brajušković G. Značaj DNK analiza u utvrđivanju biološkog srodstva. U: Šćepanović G, Stanković Z, Petrović Z (urednici). Sudskomedicinsko veštačenje nematerijalne štete. Beograd: Službeni glasnik; 2015. str. 637-44. ISBN: 978-86-519-1890-5.

***119. Savić Pavićević D. Molekularna genetika miotoničnih distrofija. U: Todorović S, Romac

S (urednici). Molekularna genetika u dečjoj neurologiji i psihijatriji III. Beograd: Stratus; 2005. str. 26-33. ISBN 86-85523-01-X.

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M52 – Rad u časopisu nacionalnog značajaNakon izbora 1x1,5=1,5

Ukupno 1x1,5=1,5

120. Milić Rašić V, Rakočević Stojanović V, Novaković I, Milenković S, Savić Pavićević D, Radojković D, Mladenović J, Kosać A, Nikodinović Glumac J, Perić S, Brkušanin M, Pešović J, Nestorović A, Jasnić-Savović J, Kojić S. NMD SerbNet – integrativni pristup u dijagnostici neuromišićnih bolesti u Srbiji. Materia Medica. 2014;30(4):1226-33.

M61 – Predavanje po pozivu sa skupa nacionalnog značaja štampano u celiniNakon izbora 2x1,5=3

Ukupno 4x1,5=6

121. Savić-Pavićević D . Anatomija i fiziologija genoma - šta smo naučili u genomskoj eri? U: Stevanović M (urednik). Geni i genom. Ciklusni projekat Geni i genom; 25. novembar 2015; Beograd, Srbija. Beograd: Srpska akademija nauka i umetnosti; 2016. str. 21-57. ISBN 978-86-7025-714-6.

122. Savić Pavićević D , Brajušković G, Romac S. Nestabilnost mikrosatelita kao molekularno-genetička osnova neuroloških i psihijatrijskih oboljenja. U: Kovačević ZL (urednik). Vek tehnologije molekularne genetike: zbornik radova naučnog skupa. Vek tehnologije molekularne genetike; 10. oktobar 2014; Novi Sad, Srbija. Beograd: Colorgrafx; 2015. str. 219-44. ISBN 978-86-81125-89-2.

***123. Romac S, Savić D, Keckarević D, Keckarević-Marković M. 2005. Dinamičke mutacije

kao uzrok naslednih neuroloških i psihijatrijskih bolesti kod dece i adolescenata. U: Zbornik radova i sažetaka Petog kongresa neurologije i psihijatrije razvojnog doba Srbije i Crne Gore (sa inostranim učešćem); 21-23 april 2005; Beograd, Srbija. str. 160-165.

124. Romac S, Čuljković B, Stojković O, Vukosavić S, Savić D, Keckarević D, Keckarević M. 2002. Dinamičke mutacije i nasledna neurodegenerativna oboljenja. U: Program i zbornik radova Prvog simpozijuma razvojne neurologije i psihijatrije; 14-15. jun 2002; Beograd, Srbija. str. 131-136.

M62 – Predavanje po pozivu sa skupa nacionalnog značaja štampano u izvoduNakon izbora 3x1=3

Ukupno 3x1=3

125. Djurica S, Šviković S, Pantović M, Karanović J, Brajušković G, Romac S, Ivković M, Savić Pavićević D. Asocijacija i epistaze mikroRNK 137 i enzima za editovanje adenozina u inozin u molekulima RNK kod šizofrenije i bipolarnog poremećaja. U: Knjiga sažetaka VI Kongresa Društva za neuronauke Srbije; 14-16. novembar 2013; Beograd, Srbija. str. 8.

126. Savić Pavićević D , Milić Rašić V, Mladenović J, Rakočević Stojanović V, Brajušković G, Jordanova A, De Jonghe P, Todorović S, Romac S. 5. Molecular genetics of myotonic disorders in Serbian patients. In: Clinical Neurophysiology, 2013, vol. 124, no. 7. Symposium of Clinical Neurophysiology with international perticipation; 2012 November 2-3, Belgrade, Serbia. p. e10.

34

127. Savić Pavićević D , Mladenović J, Rakočević Stojanović V, Pekmezović T, Karanović J, Brajušković G, Apostolski S, Todorović S, Romac S. Molekularna genetika bolesti nestabilnih ekspanzija ponovaka. U: Zbornik radovaVIII/XIV Kongresa neurologa Srbije, V kongresa Društva za nuronauke Srbije, II simpozijuma medicinskih sestara – tehničara; 29. septembar-02. oktobar 2011; Kopaonik, Srbija. str. 42.

M64 – Saopštenje sa skupa nacionalnog značaja štampano u izvoduNakon izbora 20x0,2=4

Ukupno 29x0,2=5,8

128. Karanović J, Ivković M, Jovanović V, Šviković S, Pantović Stefanović M, Damjanović A, Brajušković G, Romac S, Savić Pavićević D. Association of serotonin receptor 1A gene with bipolar disorder in Serbian population - a preliminary results. U: Engrami. 43. edukativni simpozijum Klinike za psihijatriju KCS - Bipolarni poremećaj - izazovi i pespektive; 12-13. novembar 2015; Beograd, Srbija. str. 82.

129. Rakoĉević Stojanović V, Perić S, Pešović J, Dujmović Bašuroski I, Nikolić A, Basta I, Savić Pavićević D, Drulović J, Lavrnić D (Beograd): Udruženost Devic-ove bolesti i miotoniĉnih distrofija (DM) tip 1 i tip 2 - prikaz porodice. U: Zbornik radova X/XVI Kongresa neurologa Srbije sa međunarodnim učešćem; 22-24. oktobar 2015; Novi Sad, Srbija. str. P27.

130. Rakoĉević Stojanović V, Perić S, Novaković I, Basta I, Nikolić A, Dobriĉić V, Marjanović A, Kaĉar A, Savić Pavićević D, Stević Z, Lavrnić D (Beograd): Varijabilnost multisistemske afekcije u miotoniĉnoj distrofiji tip - pouke iz srpskog registra. U: Zbornik radova X/XVI Kongresa neurologa Srbije sa međunarodnim učešćem; 22-24. oktobar 2015; Novi Sad, Srbija. str. P28.

131. Perić S, Pavlović A, Savić Pavićević D, Pešović J, Lavrnić D, Jovanović Z, Rakoĉević Stojanović V (Beograd): Ultrasonografija moždanog parenhima kod bolesnika sa miotoniĉnom distrofijom tipa 2. U: Zbornik radova X/XVI Kongresa neurologa Srbije sa međunarodnim učešćem; 22-24. oktobar 2015; Novi Sad, Srbija. str. P30.

132. Radovanović S, Perić S, Savić-Pavićević D, Dobriĉić V, Pešović J, Kostić V.S, Rakoĉević Stojanović V (Beograd): Poređenje karakteristika hoda kod bolesnika sa miotoniĉnom distrofijom tipa 1 i 2. U: Zbornik radova X/XVI Kongresa neurologa Srbije sa međunarodnim učešćem; 22-24. oktobar 2015; Novi Sad, Srbija. str. P32.

133. Kovĉić V, Rakoĉević-Stojanović V, Perić S, Pešović J, Brkušanin M, Ranum LPW, Brajušković G, Romac S, Savić Pavićević D (Beograd): Pacijenti sa miotoniĉnom distrofijom tip 2 iz Srbije nose evropske osnivaĉke haplotipove. U: Zbornik radova X/XVI Kongresa neurologa Srbije sa međunarodnim učešćem; 22-24. oktobar 2015; Novi Sad, Srbija. str. P33.

134. Brkušanin M, Kosać A, Brajušković G, Pešović J, Romac S, Milić Rašić V, Savić Pavićević D (Beograd): Unapređenje genetiĉke dijagnostike spinalne mišićne atrofije primenom metode multipleks amplifikacije ligiranih proba. U: Zbornik radova X/XVI Kongresa neurologa Srbije sa međunarodnim učešćem; 22-24. oktobar 2015; Novi Sad, Srbija. str. P103.

135. Brkušanin M, Milić Rašić V, Rakoĉević Stojanović V, Savić Pavićević D, Novaković I, Perić S, Mladenović J, Kosać A, Nikodinović Glumac J, Dobriĉić V, Milenković S, Pešović J, Radojković D, Nestorović A, Jasnić-Savović J, Kojić S (Beograd): Mreža za neuromišićne bolesti Srbije (NMD-SERBNET). U: Zbornik radova X/XVI Kongresa neurologa Srbije sa međunarodnim učešćem; 22-24. oktobar 2015; Novi Sad, Srbija. str. P104.

35

136. Pešović J, Rakoĉević-Stojanović V, Perić S, Brkušanin M, Brajušković G, Romac S, Savić Pavićević D (Beograd): Varijantni ponovci kao mogući genetiĉki modifikatori DM1. U: Zbornik radova X/XVI Kongresa neurologa Srbije sa međunarodnim učešćem; 22-24. oktobar 2015; Novi Sad, Srbija. str. P114.

137. Ostojić S, Zamurović D, Kovačević G, Savić Pavićević D. Hereditary motor and sensory neuropathy Lom type in 6-year-old boy: case report. In: Book of Abstracts of the 10th Congress of Clinical Neurophysilogy with international participation; 2014 October 31-November 1; Belgrade, Serbia. p. 80-81.

138. Pešović J, Brkušanin M, Nikolić Z, Karanović J, Brajušković G, Romac S, Savić Pavićević D. Repeat-primed PCR in diagnostic testing of repeat expansion diseases. In: Book of abstracts of the V Congress of the Serbian Genetic Society; 2014 September 28-October 2; Kladovo (Belgrade), Serbia. p. 232.

139. Brkušanin M, Kosać A, Pešović J, Brajušković G, Romac S, Milić Rašić V, Savić Pavićević D. Association of SMN2 gene copy number with clinical types of spinal muscular atrophy (SMA) in Serbian patients. In: Book of abstracts of the V Congress of the Serbian Genetic Society; 2014 September 28-October 2; Kladovo (Belgrade), Serbia. p. 78.

140. Karanović J, Pantović M, Brkušanin M, Brajušković G, Romac S, Ivković M, Savić Pavićević D. Interactions of TPH2 variants and childhood abuse as risk factors for suicide attempt in Serbian psychiatric patients. In: Book of abstracts of the V Congress of the Serbian Genetic Society; 2014 September 28-October 2; Kladovo (Belgrade), Serbia. p. 123.

141. Nikolić Z, Savić Pavićević D, Vučić N, Filipović N, Vukotić V, Romac S, Brajušković G. Assessment of association between rs895819 in miR-27a and prostate cancer risk in Serbian population. In: Book of abstracts of the V Congress of the Serbian Genetic Society; 2014 September 28-October 2; Kladovo (Belgrade), Serbia. p. 46.

142. Vučić N, Nikolić Z, Savić Pavićević D, Kanazir S, Vukotić V, Romac S, Brajušković G. Assessment of possible association between two genetic variants in NOS3 gene and male infertility in Serbian population. In: Book of abstracts of the V Congress of the Serbian Genetic Society; 2014 September 28-October 2; Kladovo (Belgrade), Serbia. p. 131.

143. Pešović J, Vojinović D, Maksimović N, Brajušković G, Romac S, Novaković I, Milič Rašić V, Savić Pavićević D. Analiza rearanžmana u genu za distrofin primenom metode multipleks amplifikacije ligiranih proba. U: Zbornik sažetaka IX/XV Kongresa neurologa Srbije sa međunarodnim učešćem;14-16. novembar 2013; Beograd, Srbija. str. 137.

144. Vojinović D, Milić Rašić V, Savić Pavićević D, Pešović J, Maksimović N, Lukić V, Mijalković G, Mladenović J, Todorović S. Lokalizacija mutacije u genu za distrofin i intelektualno funkcionisanje u mišićnoj distrofiji Dišenovog tipa. U: Zbornik sažetaka IX/XV Kongresa neurologa Srbije sa međunarodnim učešćem; 14-16. novembar 2013; Beograd, Srbija. str. 85.

145. Milic Rasic V, Nikodinovic J, Mladenovic J, De Jonghe P, Jordanova A, Baets J, Zimon M, Keckarevic Markovic M, Savic Pavicevic D, Todorovic S. 4. Neurophysiologic and clinical characteristic of neuromyotonia in new hereditary neuromuscular disorder. In: Clinical Neurophysiology, 2013, vol. 124, no. 7. Symposium of Clinical Neurophysiology with international perticipation; 2012 November 2-3; Belgrade, Serbia. p. e10.

36

146. Ivković M, Dobričić V, Damjanović A, Savić-Pavićević D, Romac S. Genetika shizofrenije – studije asocijacije. U: Zbornik radova VIII/XIV Kongresa neurologa Srbije, V kongresa Društva za nuronauke Srbije, II simpozijuma medicinskih sestara – tehničara; 29. septembar-02. oktobar 2011; Kopaonik, Srbija. str. 237.

147. Todorović S, Milić Rašić V, Romac S, Savić-Pavićević D. Genetika spinalnih mišićnih atrofija. U: Zbornik radova VIII/XIV Kongresa neurologa Srbije, V kongresa Društva za nuronauke Srbije, II simpozijuma medicinskih sestara – tehničara; 29. septembar-02. oktobar 2011; Kopaonik, Srbija. str. 240.

***148. Brajušković G, Savić Pavićević D, Romac S. Značaj otkrića varijacija u broju ponovaka

u humanom genomu za nove strategije istraživanja bolesti. In: Materia Medica, 2009, vol. 25, no. 2. XIII Congress of the Serbian Association of Pathology and Cytology with International Participation; 2009 May 27-30; Vršac, Serbia. p. 44, P17.

149. Šijačić-Nikolić M, Milovanović J, Savić Pavićević D, Brajušković G, Diklić M. Sessile Oak Different Regions Genetid Distance in Serbia. In: Book of Abstracts of the IV Congress of the Serbian Genetic Society; 2009 June 01-05; Tara, Serbia. p. 257, V-Pos-76.

150. Dobričić V, Savić D, Keckarević D, Romac S. Fridrajhova ataksija: analiza mitotičke i mejotičke nestabilnosti FRDA lokusa. U: Zbornik abstrakata Trećeg kongresa genetičara Srbije; 30. novembar-04. decembar 2004; Subotica, Srbija. str. 219, V-Pos-16.

151. Čuljković B, Savić D, Stojković O, Apostolski S, Rakočević-Stojanović V, Romac S. Učestalost DMPK alela u zdravoj jugoslovenskoj populaciji. U: Zbornik sažetaka Petog kongresa neurologa Jugoslavije; 31. maj-03. jun 2000; Zlatibor, Srbija. str. 247.

152. Savić D , Čuljković B, Stojković O, Šternić N, Stojinović-Svetel M, Kostić V, Romac S. Frekvencija MJD/SCA3 alela u zdravoj jugoslovenskoj populaciji. U: Zbornik sažetaka Petog kongresa neurologa Jugoslavije; 31. maj-03. jun 2000; Zlatibor, Srbija. str. 258.

153. Zamurović N, Čuljković B, Stojković O, Major T, Keckarević D, Savić D, Romac S. Charcot Marrie Tooth - PCR dijagnostika. U: Zbornik sažetaka Drugog kongresa genetičara Srbije; 10-13. novembar 1999; Sokobanja, Srbija. str. 246-7.

154. Keckarević D, Savić D, Major T, Zamurović N, Čuljković B, Stojković O, Vukosavić S, Romac S. Spinalna mišićna atrofija - mogućnosti prenatalne dijagnostike. U: Zbornik sažetaka Drugog kongresa genetičara Srbije; 10-13. novembar 1999; Sokobanja, Srbija. str. 252-3.

155. Major T, Čuljković B, Stojković O, Zamurović N, Keckarević D, Savić D, Romac S. Sindrom fragilnog X hromozoma: molekularna dijagnostika. U: Zbornik sažetaka Drugog kongresa genetičara Srbije; 10-13. novembar 1999; Sokobanja, Srbija. str. 257, PP22.

156. Savić D , Čuljković B, Stojković O, Major T, Zamurović N, Keckarević D, Romac S. Molekularna genetika i dijagnostika miotonične distrofije. U: Zbornik sažetaka Drugog kongresa genetičara Srbije; 10-13. novembar 1999; Sokobanja, Srbija. str. 265-6, PP29.

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М66а– Stručni radovi, naučno-popularni rad i popularni radNakon izbora 0,2x0=0

Ukupno 0,2x2=0,4***

157. Savić D , Keckarević D, Čuljković B, Keckarević M, Stevanović M, Romac S. Osnovne pretpostavke upotrebe molekularne biolgije u forenzičke svrhe. U: Der Šeregelj E (urednik). Bilten sudske prakse. Savetovanje Naučno metodološki pristup u pojednim sudskim veštačenjima; 2004; Subotica, Srbija. str. 113-116. ISBN 86-85285-00-3.

158. Keckarević D, Savić D, Čuljković B, Keckarević M, Stevanović M, Romac S. 2004. Metodološki pristup saklupljanju i analizi bioloških tragova. U: Der Šeregelj E (urednik). Bilten sudske prakse. Savetovanje Naučno metodološki pristup u pojednim sudskim veštačenjima; 2004; Subotica, Srbija. str. 117-129. ISBN 86-85285-00-3.

M71 – Odbranjena doktorska disertacijaM71=6

159. Savić D . Komparativna analiza HD gena kod vrsta različite evolucione starosti. Doktorska disertacija. Biološki fakultet, Univerzitet u Beogradu. 2004. Mentor prof. S. Romac.

M72 – Odbranjena magistarska tezaM72=3

160. Savić D . Molekularna genetika miotonične distrofije – intergeneracijska i somatska nestabilnost broja CTG ponovaka u MtPK genu. Magistarski rad. Biološki fakultet, Univerzitet u Beogradu. 2000. Mentor prof. S. Romac.

Diplomski rad161. Savić D . Populaciona analiza MJD1/SCA3 gena odgovornog za Machado-Josephovu

bolest (spinocerebelarnu ataksiju tip 3). Diplomski rad. Biološki fakultet, Univerzitet u Beogradu. 1998. Mentor prof. S. Romac.

3.3. Ostale naučne aktivnosti

Učešće na međunarodnom projektu Nakon izbora 2x2=4

Ukupno 2x2=4

1. Networking towards Clinical Application of Antisense Mediated Exon Skipping. Biomedicine and Molecular Biosciences COST Action —BM1207. Period: 2013-2017. Chair of the Action: A. Aartsma-Rus. Management Committee Substitute, Serbia: D. Savić - Pavićević .

2. PRACTICAL, Study group: PROSTATSERBIA (SNPs and prostate cancer risk in Serbian population). Funded by: The Institute of Cancer Research: Royal Cancer Hospital, London, UK. Principal Investigator: G. Brajušković.

38

Rukovođenje projektom bilateralne saradnjeNakon izbora 1x2=2

Ukupno 1x2=2

1. Editovanje serotoninskog receptora 2C i ekspresija SNORD115 u mišjim modelima pod izmenjenim sredinskim uslovima. Bilateralni projekat sa Slovenijom. Еv. broj: 451-03-39/2016-09/15/01. Period: 2016-2017. Rukovodioci: D. Savić-Pavićević (Srbija), T. Bratkovič (Slovenija).

Učešće u projektu bilateralne saradnjeNakon izbora 2x1=2

Ukupno 2x1=2

1. Mehanizam patogeneze umnoženih ponovaka u genu C9orf72 kod amiotrofične lateralne skleroze i frontotemporalne degeneracije. Bilateralni projekat sa Slovenijom. Ev. broj 451-03-3095/2014-09/44. Period: 2014-2015. Rukovodioci: P. Anđus (Srbija), B. Rogelj (Slovenija).

2. Molekularni i genomski markeri amiotrofične lateralne skleroze. Bilateralni projekat sa Italijom. Period: 2013-2014. Rukovodioci: P. Anđus, F. Michetti.

Rukovođenje nacionalnim projektomNakon izbora 1x4=4

Ukupno 1x4=4

1. Analiza promena u strukturi genoma kao dijagnostički i prognostički parametar humanih bolesti. Projekat osnovnih istraživanja u oblasti biologije OI 173016 (MPNTR, R Srbija). Period: 2011-2016. Rukovodilac: D. Savić-Pavićević (do decembra 2015. – S. Romac)

Učešće u nacionalnom projektuNakon izbora 0

Ukupno 4x1=4***

1. Molekularna genetika naslednih neurodegenerativnih i psihijatrijskih oboljenja. Projekat osnovnih istraživanja u oblasti biologije #143013 (MNTR, R Srbija). Period: 2005-2010. Rukovodilac: S. Romac.

2. Molekularna genetika trinukleotidnih ekspanzija. Projekat osnovnih istraživanja u oblasti biologije #1521 (MNZŽ, R Srbija). Period: 2000-2005. Rukovodilac: S. Romac.

3. Istraživanje genetičke osnove neuroloških bolesti: genotipsko-fenotipske korelacije. Projekat osnovnih istraživanja u oblasti medicine #1988 (MNZŽ, R Srbija). Period: 2000-2005. Rukovodilac: V. Kostić.

4. Molekularna dijagnostika naslednih bolesti u medicini. Strateški projekat broj S.6.35.75.0126 (MNT, R Srbija). Period: 1999-2000. Rukovodilac: S. Romac.

Recenzija publikacija kategorije M20Nakon izbora 12x1,5=18

Ukupno 13x1,5=19,5

1. Genetic predisposition to ischaemic stroke by RAGE and HMGB1 gene polymorphisms in a southern Chinese population. Oncotarget. #034154

39

2. High-Coverage Whole-Exome Sequencing Identifies Candidate Genes for Suicide in Victims with Major Depressive Disorder. Sci Reports. SREP-17-06301-T

3. Aberrant splicing of annexin VII by PTB impairs muscle cell differentiation in myotonic dystrophy type 1. PLOS Genet. PGENETICS-D-13-01849

4. DNA Polymorphism and Alteration in Genomic DNA Isolated of Early Fourth Instars of Aedes aegypti L. (Diptera: Culicidae) Exposed to Achyranthes aspera (Amaranthaceae) Extracts. Arch Biol Sci. ID1229

5. Anti-Proliferative and Apoptotic Action of Sophocarpine in Human Prostate Cancer Cell Lines. Arch Biol Sci. ID845

6. RME-1 isrequired for lifespan extension and increased resistance to stresses associated with decreased insulin/IGF-1-like signaling pathway in C. elegans. Arch Biol Sci. ID552

7. Hippo signaling protein MST1 regulates osteoclast differentiation by interacting with integrin-linked kinase (ILK) and modulating actin structures. Arch Biol Sci.

8. miR-29b regulates cell proliferation and invasion in human ovarian clear cell carcinoma via targeting LOX. Arch Biol Sci.

9. MiRNA-20A expression and bioinformatics analysis in serum from pregnant women with macrosomia. Arch Biol Sci.

10. A double-enriched genomic library procedure for the isolation of novel simple sequence repeats from the mangrove crab Ucides cordatus (Brachyura: Ocypodidae). Arch Biol Sci. 12052014ABS

11. Efficacy of potential antipsychotic LEK-8829 with intrinsic activity at dopamine D1 receptors. Slovenian Veterinary Research

12. MiR-139-3p is related to left ventricular hypertrophy and cardiomyocyte apoptosis in two-kidney one-clip hypertensive rats. Arch Biol Sci. 08202014ABS

***13. Regulation of the SOX3 gene expression by retinoic acid during early phases of neural

differentiation of human embryonal carcinoma cell line NT2/D1. Physiol Res.

Recenzija drugih publikacija

14. Zebrafish (Danio rerio) in Deciphering Molecular Mechanisms of Human Diseases. Biologia Serbica.

15. Genomics as a Basis for Precision Medicine. Biologia Serbica.

Recenzija monografije kategorije M42

1. Snežana Kojić. Struktura i dinamika sarkomere. Zemun: Alta Nova; 2016. ISBN978-86-82679-12-7.

Članstvo u uredništvu međunarodnih časopisa/nacionalnih časopisa/zbornika radova sa naučnih skupova

Nakon izbora 1x3+1x0,5=3,5Ukupno 1x3+1x0,5=3,5

1. Član Uređivačkog odbora Archives of Biological Science (2014–).

2. Urednik po pozivu posebne sveske Biologia Serbica posvećene Prvom kongresu molekularnih biologa Srbije sa međunarodnim učešćem (CoMBoS); 20-22. septembar 2017; Beograd, Srbija.

40

Citiranost

Ukupno navedenih citata bez autocitata 336 Ukupno citiranih radova 48 Broj citata u publikacijama sa IF (JCR lista) – 277 (57 M21a, 75 M21, 74 M22) h index = 9 Broj citata u međunarodnim monografijama 40 Broj citata u međunarodnim doktorskim tezama 19

Citati u publikacijama sa JCR liste

Rad 4 Zimoń M, et al. Loss-of-function mutations in HINT1 cause axonal neuropathy with neuromyotonia. Nat Genet. 2012;44(10):1080-3 citiraju:

1. Li BJ, et al. Social isolation induces schizophrenia-like behavior potentially associated with HINT1, NMDA receptor 1, and dopamine receptor 2. Neuroreport. 2017;28(8):462-469. (M23)

2. Motzik A, et al. Post-translational modification of HINT1 mediates activation of MITF transcriptional activity in human melanoma cells. Oncogene. 2017. doi: 10.1038/onc.2017.81. (M21a)

3. Proix T, et al. Individual brain structure and modelling predict seizure propagation. Brain. 2017;140(3):641-654. (M21a)

4. Atkinson D, et al. Sphingosine 1-phosphate lyase deficiency causes Charcot-Marie-Tooth neuropathy. Neurology. 2017;88(6):533-542. (M21a)

5. Peeters K, et al. Axonal neuropathy with neuromyotonia: there is a HINT. Brain. 2016;140(4):868-877. (M21a)

6. Drew AP, et al. A 1.35 Mb DNA fragment is inserted into the DHMN1 locus on chromosome 7q34-q36.2. Hum Genet. 2016; 135(11):1269-1278. (M21a)

7. Veltsista D and Chroni E. A first case report of HINT1-related axonal neuropathy with neuromyotonia in a Greek family. Clin Neurol Neurosurg. 2016;148:85-7. (M23)

8. Hong YB, et al. DGAT2 Mutation in a Family with Autosomal-Dominant Early-Onset Axonal Charcot-Marie-Tooth Disease. Hum Mutat. 2016;37(5):473-80. (M21)

9. Rauchenzauner M, et al. A Novel Variant in the HINT1 Gene in a Girl with Autosomal Recessive Axonal Neuropathy with Neuromyotonia: Thorough Neurological Examination Gives the Clue. Neuropediatrics. 2016;47(2):119-22. (M23)

10. Albulym OM, et al. MORC2 mutations cause axonal Charcot-Marie-Tooth disease with pyramidal signs. Ann Neurol. 2016;79(3):419-27. (M21a)

11. Shi Z, et al. Hint1 Up-Regulates IκBα by Targeting the β-TrCP Subunit of SCF E3 Ligase in Human Hepatocellular Carcinoma Cells. Dig Dis Sci. 2016;61(3):785-94. (M22)

12. Kancheva D, et al. Novel mutations in genes causing hereditary spastic paraplegia and Charcot-Marie-Tooth neuropathy identified by an optimized protocol for homozygosity mapping based on whole-exome sequencing. Genet Med. 2016;18(6):600-7. (M21a)

13. Montecchiani C, et al. ALS5/SPG11/KIAA1840 mutations cause autosomal recessive axonal Charcot-Marie-Tooth disease. Brain. 2015;139(Pt1):73-85. (M21a)

14. Gess B, et al. Ascorbic acid for the treatment of Charcot-Marie-Tooth disease. Cochrane Database Syst Rev. 2015;(12):CD011952. (M21a)

15. Fernández-Ramos JA, et al. [Experience in molecular diagnostic in hereditary neuropathies in a pediatric tertiary hospital]. Rev Neurol. 2015;61(11):490-8. (M23)

16. Dang YH, et al. HINT1 is involved in the behavioral abnormalities induced by social isolation rearing. Neurosci Lett. 2015;607:40-5. (M23)

17. Horga A, et al. Absence of HINT1 mutations in a UK and Spanish cohort of patients with inherited neuropathies. J Neurol. 2015; 262(8):1984-6. (M21)

18. Jerath NU, et al. A case of neuromyotonia and axonal motor neuropathy: A report of a HINT 1 mutation in the United States. Muscle Nerve. 2015;52(6):1110-3. (M22)

19. Ahmed A and Simmons Z. Isaacs syndrome: A review. Muscle Nerve. 2015;52(1):5-12. (M22)20. Baets J, et al. Defects of mutant DNMT1 are linked to a spectrum of neurological disorders.

Brain. 2015;138(Pt 4):845-61. (M21a)21. Jerath NU and Shy ME. Hereditary motor and sensory neuropathies: Understanding molecular

pathogenesis could lead to future treatment strategies. Biochim Biophys Acta: Molecular Basis of Disease. 2015;1852(4):667-678. (M21)

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22. Garzón J, et al. HINT1 protein: a new therapeutic target to enhance opioid antinociception and block mechanical allodynia. Neuropharmacology. 2015;89:412-23. (M21a)

23. Zimoń M, et al. Unraveling the genetic landscape of autosomal recessive Charcot-Marie-Tooth neuropathies using a homozygosity mapping approach. Neurogenetics. 2015;16(1):33-42. (M21)

24. Laššuthová P, et al. Mutations in HINT1 are one of the most frequent causes of hereditary neuropathy among Czech patients and neuromyotonia is rather an underdiagnosed symptom. Neurogenetics. 2015;16(1):43-54. (M21)

25. Ardissone A, et al. Childhood onset of acquired neuromyotonia: association with a ganglioneuroma. Muscle Nerve. 2015;51(4):620-1. (M22)

26. Boaretto F, et al. Novel loss-of-function mutation of the HINT1 gene in a patient with distal motor axonal neuropathy without neuromyotonia. Muscle Nerve. 2015;52(4):688-9. (M22)

27. Baets J, De Jonghe P, Timmerman V. Recent advances in Charcot-Marie-Tooth disease. Curr Opin Neurol. 2014;27(5):532-40. (M21a)

28. Gutmann L and Shy M. Update on Charcot-Marie-Tooth disease. Curr Opin Neurol. 2015 Oct;28(5):462-7. (M21a; IF2014 5,307)

29. Krakowiak A, et al. Interactions of cellular histidine triad nucleotide binding protein 1 with nucleosides 5'-O-monophosphorothioate and their derivatives - Implication for desulfuration process in the cell. Biochim Biophys Acta: General Subjects. 2014;1840(12):3357-66. (M21)

30. Pareyson D, Saveri P, Piscosquito G. Charcot-Marie-Tooth Disease and Related Hereditary Neuropathies: From Gene Function to ssociated Phenotypes. Curr Mol Med. 2014; (M21)

31. Schabhüttl M, et al. Whole-exome sequencing in patients with inherited neuropathies: outcome and challenges. J Neurol. 2014;261(5):970-82. (M21)

32. Zhao H, et al. Exome sequencing reveals HINT1 mutations as a cause of distal hereditary motor neuropathy. Eur J Hum Genet. 2014;22(6):847-50. (M21)

33. Seburn KL, et al. Lack of neuropathy-related phenotypes in hint1 knockout mice. J Neuropathol Exp Neurol. 2014;73(7):693-701. (M21)

34. Mei Y, et al. Effect of microRNA-210 on prognosis and response to chemotherapeutic drugs in pediatric acute lymphoblastic leukemia. Cancer Sci. 2014;105(4):463-72. (M22)

35. Caetano JS, et al. Autosomal recessive axonal neuropathy with neuromyotonia: a rare entity. Pediatr Neurol. 2014;50(1):104-7. (M23)

36. Timmerman V, Strickland AV, Züchner S. Genetics of Charcot-Marie-Tooth (CMT) Disease within the Frame of the Human Genome Project Success. Genes (Basel). 2014;5(1):13-32. (M23)

37. Linde CI, et al. Histidine triad nucleotide-binding protein 1 (HINT1) regulates Ca(2+) signaling in mouse fibroblasts and neuronal cells via store-operated Ca (2+) entry pathway. Am J Physiol Cell Physiol. 2013;304(11):C1098-104. (M21)

38. Loescher WN, et al. Peripheral Nerve Hyperexcitability - Cramp-Fasciculation Syndrome, Neuromyotonia and Morvan's Syndrome. KLIN NEUROPHYSIOL 2014; 45(4): 201-206. (M23)

39. Sánchez-Blázquez P, et al. Cannabinoid receptors couple to NMDA receptors to reduce the production of NO and the mobilization of zinc induced by glutamate. Antioxid Redox Signal. 2013;19(15):1766-82. (M21a)

40. Maize KM, Wagner CR, Finzel BC. Structural characterization of human histidine triad nucleotide-binding protein 2, a member of the histidine triad superfamily. FEBS J. 2013;280(14):3389-98. (M21)

41. Zhou X, et al. Kinetic mechanism of human histidine triad nucleotide binding protein 1. Biochemistry. 2013;52(20):3588-600. (M22)

42. Tazir M, et al. Autosomal recessive Charcot-Marie-Tooth disease: from genes to phenotypes. J Peripher Nerv Syst. 2013;18(2):113-29. (M22)

Rad 7 Karanović J, et al. Tryptophan hydroxylase 1 variant rs1800532 is associated with suicide attempt in Serbian psychiatric patients but does not moderate the effect of recent stressful life events. Suicide and Life Threatening Behavior. 2016;46(6):664-8 citira:

43. Sudol K and Mann JJ. Biomarkers of Suicide Attempt Behavior: Towards a Biological Model of Risk Curr Psychiatry Rep. 2017;19(6):31. (M21)

Rad 8 Nikolić Z, et al. Association between a Genetic Variant in the hsa-miR-146a Gene and Cancer Risk: An Updated Meta-Analysis. Public Health Genomics. 2015;18(5):283-98 citira:

42

44. Garcia AI, et al. Mutation screening of MIR146A/B and BRCA1/2 3'-UTRs in the GENESIS study. Eur J Hum Genet. 2016;24(9):1324-9. (M21)

Rad 9 Nikolić Z, et al. Assessment of association between genetic variants in microRNA genes hsa-miR-499, hsa-miR-196a2 and hsa-miR-27a and prostate cancer risk in Serbian population. Exp Mol Pathol. 2015;99(1):145-150 citiraju:

45. Wang YH, et al. Association between Polymorphisms in MicroRNAs and Risk of Urological Cancer: A Meta-Analysis Based on 17,019 Subjects. Front Physiol. 2017;8:325. (M21)

46. Zhang H, et al Association of two microRNA polymorphisms miR-27 rs895819 and miR-423 rs6505162 with the risk of cancer. Oncotarget. 2017. doi: 10.18632/oncotarget.16443. (M21)

47. Liu X, Han Z, Yang C. Associations of microRNA single nucleotide polymorphisms and disease risk and pathophysiology. Clin Genet. 2016. doi: 10.1111/cge.12950. (M21)

48. Li D, et al. Associations between genetic variants located in mature microRNAs and risk of lung cancer. Oncotarget. 2016;7(27):41715-41724. (M21)

49. Wang J, et al. Correlation between miRNA-196a2 and miRNA-499 polymorphisms and bladder cancer. Int J Clin Exp Med 2016;9(11):20484-20488. (M22)

50. Ni J and Huang Y. Role of polymorphisms in miR-146a, miR-149, miR-196a2 and miR-499 in the development of ovarian cancer in a Chinese population. Int J Clin Exp Pathol. 2016;9(5):5706-5711. (M22)

51. Li M, et al. Association between the pre-miR-196a2 rs11614913 polymorphism and gastric cancer susceptibility in a Chinese population. Genet Mol Res. 2016;15(2). (M23)

52. Sun XC, et al. miR-146a and miR-196a2 polymorphisms in ovarian cancer risk. Genet Mol Res. 2016;15(3). (M23)

53. Hashemi M, et al. Association between single nucleotide polymorphism in miR-499, miR-196a2, miR-146a and miR-149 and prostate cancer risk in a sample of Iranian population. J Adv Res. 2016;7(3):491-8.

Rad 10 Karanovic J, et al. Joint effect of ADARB1 gene, HTR2C gene and stressful life events on suicide attempt risk in patients with major psychiatric disorders. World J Biol Psychiatry. 2015;16(4):261-71 citiraju:

54. Sudol K and Mann JJ. Biomarkers of Suicide Attempt Behavior: Towards a Biological Model of Risk Curr Psychiatry Rep. 2017;19(6):31. (M21)

55. Yao J, et al. Enhanced Expression of Serotonin Receptor 5-Hydroxytryptamine 2C is Associated with Increased Feather Damage in Dongxiang Blue-Shelled Layers. Behav Genet. 2017; 47(3):369-374. (M21)

56. Molina-Guzman G, et al. Gender differences in the association between HTR2C gene variants and suicidal behavior in a Mexican population: a case-control study. Neuropsychiatr Dis Treat. 2017;13:559-566. (M22)

57. van der Laan S, et al. Emerging RNA editing biomarkers will foster drug development. Drug Discov Today. 2017. doi: 10.1016/j.drudis.2017.01.017. (M21a)

58. Weissmann D, et al. Region-specific alterations of A-to-I RNA editing of serotonin 2c receptor in the cortex of suicides with major depression. Transl Psychiatry. 2016;6(8):e878. (M21a)

59. Gasparini CF, Smith RA, Griffiths LR. Genetic insights into migraine and glutamate: a protagonist driving the headache. J Neurol Sci. 2016;367:258-68. (M22)

60. Kim JS and Lee SH. Influence of interactions between genes and childhood trauma on refractoriness in psychiatric disorders. Prog Neuropsychopharmacol Biol Psychiatry. 2016; 70:162-9. (M21)

Rad 11 Sarajlija A, et al. Epidemiology of Rett syndrome in Serbia: prevalence, incidence and survival. Neuroepidemiology. 2015;44(1):1-5 citiraju:

61. Sherry EB, Lee P, Choi IY. In Vivo NMR Studies of the Brain with Hereditary or Acquired Metabolic Disorders. Neurochem Res. 2015;40(12):2647-85. (M22; IF2015 2,472)

62. Tarquinio DC, et al. The Changing Face of Survival in Rett Syndrome and MECP2-Related Disorders. Pediatr Neurol. 2015;53(5):402-11. (M22)

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Rad 12 Peric S, et al. Frontostriatal dysexecutive syndrome: a core cognitive feature of myotonic dystrophy type 2. J Neurol. 2015;262(1):142-8 citiraju:

63. Meola G, et al. Biomolecular diagnosis of myotonic dystrophy type 2: a challenging approach. J Neurol. 2017. doi: 10.1007/s00415-017-8504-1. (M21)

64. Peric S, et al. Brain positron emission tomography in patients with myotonic dystrophy type 1 and type 2. J Neurol Sci. 2017;378:187-192. (M22)

65. Meola G and Cardani R. Myotonic dystrophy type 2 and modifier genes: an update on clinical and pathomolecular aspects. Neurol Sci. 2017. doi:10.1007/s10072-016-2805-5. (M23)

66. Bosco G, et al. Workshop Report: consensus on biomarkers of cerebral involvement in myotonic dystrophy, 2-3 December 2014,Milan, Italy. Neuromuscul Disord. 2015;25(10):813-23. (M22)

67. Bugiardini E, et al. Consensus on cerebral involvement in myotonic dystrophy: workshop report: May 24-27, 2013, Ferrere (AT), Italy. Neuromuscul Disord. 2014;24(5):445-52. (M22)

68. Schneider-Gold C, et al. Cortical and Subcortical Grey and White Matter Atrophy in Myotonic Dystrophies Type 1 and 2 Is Associated with Cognitive Impairment, Depression and Daytime Sleepiness. PLoS One. 2015; 26;10(6):e0130352. (M21)

69. Krudop WA and Pijnenburg YA. Historical Evolution of the Frontal Lobe Syndrome. Psychopathology. 2015;48(4):222-9 (M22)

Rad 13 Nikolić Z, et al. Association between genetic variant in hsa-miR-146a gene and prostate cancer progression: evidence from Serbian population. Cancer Causes Control. 2014;25(11):1571-5 citiraju:

70. Wang YH, Hu HN, Weng H, Chen H, Luo CL, Ji J, Yin CQ, Yuan CH, Wang FB. Association between Polymorphisms in MicroRNAs and Risk of Urological Cancer: A Meta-Analysis Based on 17,019 Subjects. Front Physiol. 2017 ;8:325. (M21; IF2016 4,134)

71. Su R, Li W, Luo R. Association between miR-146a, miR-149, miR-196a2 and miR-499 gene polymorphisms and the susceptibility to gastric cancer in a Chinese population. Int J Clin Exp Pathol. 2016;9(2):2192-2199 (M22)

72. Liu HT, et al. LncRNA PVT1 regulates prostate cancer cell growth by inducing the methylation of miR-146a. Cancer Med. 2016;5(12):3512-3519. (M22)

Rad 14 Ivković M, et al. Retinoic acid induced 1 gene and clinical subtypes of schizophrenia: an associ-ation study. Psychiatry Res. 2011;188(2):297-8 citira:

73. Tan EC, et al. Association of premenstrual/menstrual symptoms with perinatal depression and a polymorphic repeat in the polyglutamine tract of the retinoic acid induced 1 gene. J Affect Disord. 2014;161:43-6. (M21)

Rad 15 Kecmanović M, et al. Coexistence of Unverricht-Lundborg disease and congenital deafness: molecular resolution of a complex comorbidity. Epilepsia. 2009;50(6):1612-5 citiraju:

74. Kecmanović M, et al. A shared haplotype indicates a founder event in Unverricht-Lundborg disease patients from Serbia. Int J Neurosci. 2014;124(2):102-9. (M23)

75. Canafoglia L, et al. Electroclinical presentation and genotype-phenotype relationships in patients with Unverricht-Lundborg disease carrying compound heterozygous CSTB point and indel mutations. Epilepsia. 2012;53(12):2120-7. (M21)

Rad 16 Keckarević-Marković M, et al. Mutational analysis of GJB1, MPZ, PMP22, EGR2, and LITAF/SIMPLE in Serbian Charcot-Marie-Tooth patients. J Peripher Nerv Sys. 2009;4(2):125-36 citiraju:

76. Sanmaneechai O, et al. Genotype-phenotype characteristics and baseline natural history of heritable neuropathies caused by mutations in the MPZ gene. Brain. 2015;138(Pt 11):3180-92. (M21a)

77. Sinkiewicz-Darol E, et al. The LITAF/SIMPLE I92V sequence variant results in an earlier age of onset of CMT1A/HNPP diseases. Neurogenetics. 2015;16(1):27-32. (M21)

78. Verma A. Next-generation sequencing and genetic diagnosis of Charcot-Marie-Tooth disease. Ann Indian Acad Neurol. 2014;17(4):383-6. (M23)

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79. Liu L, et al. Two novel MPZ mutations in Chinese CMT patients. J Peripher Nerv Syst. 2013;18(3):256-60. (M22)

80. Keckarevic Markovic MP, et al. An algorithm for genetic testing of Serbian patients with demyelinating Charcot-Marie-Tooth. Genet Test Mol Biomarkers. 2013;17(1):85-7. (M23)

81. Vrancken AF, Spliet WG, van Ruissen F. X-linked Charcot-Marie-Tooth disease with novel c.47A>T GJB1 gene mutation. J Peripher Nerv Syst. 2010;15(2):156-7. (M21)

Rad 17 Stevanović M, et al. Human Y-specific STR haplotypes in population of Serbia and Montenegro. Forensic Sci Int. 2007;171(2-3):216-21 citiraju:

82. Lowery RK, et al. Sub-population structure evident in forensic Y-STR profiles from Armenian geographical groups. Leg Med (Tokyo). 2013;15(2):85-90. (M22)

83. Cockerton S, McManus K, Buckleton J. Interpreting lineage markers in view of subpopulation effects. Forensic Sci Int Genet. 2012;6(3):393-7. (M21a)

84. Jakovski Z, et al. Genetic data for 17 Y-chromosomal STR loci in Macedonians in the Republic of Macedonia. Forensic Sci Int Genet. 2011;5(4):e108-11. (M21)

85. Ehler E, et al. Y-chromosomal diversity of the Valachs from the Czech Republic: model for isolated population in Central Europe. Croat Med J. 2011;52(3):358-67. (M22)

86. Cenanović M, et al. Diversity of Y-short tandem repeats in the representative sample of the population of Canton Sarajevo residents, Bosnia and Herzegovina. Coll Antropol. 2010;34(2):545-50. (M22)

Rad 18 Keckarević D, et al. Population data on 14 STR loci from population of Serbia and Montenegro (new and renewed data). Forensic Sci Int. 2005;151(2-3):315-6 citiraju:

87. Tsybovskii IS, et al. Developing forensic reference database by 18 autosomal STR for DNA identification in Republic of Belarus. Russian Journal of Genetics. 2017;53(2):275-284.(M23)

88. Novković T, et al. Genetic polymorphisms of 15 AmpFlSTR Identifiler loci in a Serbian population. Forensic Sci Int: Genetics. 2010;4(5):e149-e150. (M21)

89. Egyed B, et al. Analysis of the population heterogeneity in Hungary using fifteen forensically informative STR markers. Forensic Sci Int. 2006;158(2-3):244-9. (M22)

90. Egyed B, Füredi S, Padar Z. Population genetic study in two Transylvanian populations using forensically informative autosomal and Y-chromosomal STR markers. Forensic Sci Int. 2006;164(2-3):257-65. (M22)

Rad 19 Čuljković B, et al. Poly(A) tailing of ancient DNA: a method for reproducible microsatellite genotyping. Anal Biochem. 2003;318(1):124-31 citiraju:

91. Beja-Pereira A, et al. Advancing ecological understandings through technological transformations in noninvasive genetics. Mol Ecol Resour. 2009;9(5):1279-301. (M23)

92. Demastes JW, et al. Phylogeography of the blue-spotted salamander, Ambystoma laterale (Caudata: Ambystomatidae). American midland naturalist. 2007;157(1):149-161. (M23)

Rad 20 Savić D, et al. 250 CTG repeats in DMPK is a threshold for correlation of expansion size and age at onset of juvenile-adult DM1. Hum Mutat. 2002;19(2):131-9 citiraju:

93. Lian M, et al. Single-Tube Dodecaplex PCR Panel of Polymorphic Microsatellite Markers Closely Linked to the DMPK CTG Repeat for Preimplantation Genetic Diagnosis of Myotonic Dystrophy Type 1. Clin Chem. 2017;63(6):1127-1140. (M21a)

94. Ambrose KK, et al. Analysis of CTG repeat length variation in the DMPK gene in the general population and the molecular diagnosis of myotonic dystrophy type 1 in Malaysia. BMJ Open. 2017;7(3):e010711.(M21)

95. Koutsoulidou A, et al. Elevated Muscle-Specific miRNAs in Serum of Myotonic Dystrophy Patients Relate to Muscle Disease Progress. PLoS One. 2015;10(4):e0125341. (M21)

96. Lian M, et al. Efficient and highly sensitive screen for myotonic dystrophy type 1 using a one-step triplet-primed PCR and melting curve assay. J Mol Diagn. 2015;17(2):128-35. (M21)

97. van Blitterswijk M, et al. Association between repeat sizes and clinical and pathological characteristics in carriers of C9ORF72 repeat expansions (Xpansize-72): a cross-sectional cohort study. Lancet Neurol. 2013;12(10):978-88. (M21a)

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98. Andersen G, et al. Muscle phenotype in patients with myotonic dystrophy type 1. Muscle Nerve. 2013;47(3):409-15. (M22)

99. Udd B and Krahe R. The myotonic dystrophies: molecular, clinical, and therapeutic challenges. Lancet Neurol. 2012;11(10):891-905. (M21a; Clinical Neurology 1/192; IF201223,917)

100. Morales F, et al. Somatic instability of the expanded CTG triplet repeat in myotonic dystrophy type 1 is a heritable quantitative trait and modifier of disease severity. Hum Mol Genet. 2012;21(16):3558-67. (M21a)

101. Radvansky J and Kadasi L. The expanding world of myotonic dystrophies: how can they be detected? Genet Test Mol Biomarkers. 2010;14(6):733-41. (M23)

102. Kim HS, et al. Myotonic dystrophy type I combined with X-linked dominant Charcot-Marie-Tooth neuropathy. Neurogenetics. 2010;11(4):425-33. (M21)

103. Kim SY, et al. Molecular and clinical characteristics of myotonic dystrophy type 1 in koreans. Korean J Lab Med.(Ann Lab Med) 2008;28(6):483-92.(M23)

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321. Kim CH. Environmental Tobacco Smoke, Genetic Susceptibility, and Lung Cancer among Never Smokers. UNIVERSITY OF CALIFORNIA. 2016 – Rad 8, Nikolić Z, et al. Public Health Genomics. 2015;18(5):283-98.

322. Mayo de Andrés S. Búsqueda e identificación de nuevas causas genéticas o epigenéticas de trastornos del neurodesarrollo. Vniverzitat de Valencia. 2015 – Rad 11, Sarajlija A, et al. Neuroepidemiology. 2015;44(1):1-5.

323. HELENA REZENDE SILVA MENDONCA. DISTROFIA MIOTONICA TIPO 1:ESTUDO NEUROPSICOLOGICO E DE RESSONANCIA MAGNETICA CEREBRAL. UNICAMP, Campinas, Brazil. 2015 – Rad 12, Peric S, et al. J Neurol. 2015;262(1):142-8.

324. Elena Sinkiewicz-Darol. Udział czynnika genetycznegow zmiennosci fenotypowej choroby Charcot-Marie-Tooth. Mossakowski Medical Research Centre, Polish Academy of Sciences. 2012 – Rad 16, Keckarević-Marković M, et al. J Peripher Nerv Sys. 2009;4(2):125-36.

325. Ehler E. Y-chromosomal polymorphisms in the Czech population with focus on Moravian Valachs: evolutionary anthropology study. Univerzita Karlova, Faculty of Science. 2017 – Rad 17, Stevanović M, et al. Forensic Sci Int. 2007;171(2-3):216-21.

326. Higham CF. Dynamic DNA and human disease: mathematical modelling and statistical inference for myotonic dystrophy type 1 and Huntington disease. PhD thesis, University of Glasgow. 2013 – Rad 20, Savić D, et al. Hum Mutat. 2002;19(2):131-9.

327. Higham CF. Dynamic DNA and human disease: mathematical modelling and statistical inference for myotonic dystrophy type 1 and Huntington disease. PhD thesis, University of Glasgow. 2013 – Rad 34, Mladenović J, et al. Eur J Neurol. 2006;13(5):451-4.

328. Yu F. The financial impact of genetic information on the insurance industry. PhD Thesis. Heriot-Watt University. 2010 – Rad 34, Mladenović J, et al. Eur J Neurol. 2006;13(5):451-4.

329. María del Carmen Crespo Puras. Análisis de la situación sociosanitaria y su impacto en la calidad de vida de los afectados por distrofia miotónica en la Comunidad de Madrid. TESIS DOCTORAL. UNIVERSIDAD COMPLUTENSE DE MADRID. 2015 – Rad 35, Mladenović J, et al. Clin Neurol Neurosurg. 2006;108(8):757-60.

330. Annette Neumayr. Häufigkeit derproximalen myotonen Myopathie (PROMM / DM2) im Vergleich zur myotonen Dystrophie (DM1)in der deutschen Bevölkerung Medizinischen FakultätderBayerischen Julius-Maximillians-Universität Würzburg. 2007 – Rad 35, Mladenović J, et al. Clin Neurol Neurosurg. 2006;108(8):757-60.

331. Friedman, Meyer J. Polyglutamine domain modulates multiple TBP interactions: Implications for its normal function and role in neurodegeneration Emory University, 2008 – Rad 38, Alendar A, et al. Acta Neurol Scand. 2004;109(3):185-7.

332. Paudel R. Genetic and neuropathological study of primary and secondary dystonic syndromes.Doctoral thesis. UCL (University College London). 2015 – Rad 40, Topisirović I, et al. Clin Genet. 2002;62(4):321-4.

333. Daughters RS. RNA gain of function effects in spinocerebellar ataxia type 8. Doctoral Disertation. University of Minnesota. 2007 – Rad 40, Topisirović I, et al. Clin Genet. 2002;62(4):321-4.

334. Paucar Martin. Genotype-phenotype characterization of familial hyperkinetic movement disorders: emphasis on ataxia and brain calcifications. Karolinska University. 2017 – Rad 56, Keckarević M, et al. Int J Neurosci. 2005;115(2):299-301.

335. Niccolo Emanuele Mencacci. Dissecting the Genetic Basis of Parkinson Disease, Dystonia and Chorea. Doctoral thesis. UCL (University College London). 2016 – Rad 56, Keckarević M, et al. Int J Neurosci. 2005;115(2):299-301.

336. Schneider, K.S.A.I.M. Electrophysiological biomarkers in genetic movement disorders. Doctoral thesis, UCL (University College London). 2008 – Rad 56, Keckarević M, et al. Int J Neurosci. 2005;115(2):299-301.

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3.4. Oblasti istraživanja i pregled naučnog rada

Oblast istraživanja D. Savić-Pavićević je humana molekularna genetika. Bavi se izučavanjem molekularno genetičke osnove, populacione genetike i genetičke epidemiologije retkih bolesti, pre svega neuromišićnih i neuroloških, ali i čestih bolesti, kao što su psihijatrijska oboljenja i karcinom prostate. D. Savić-Pavićević izučava i populaciono genetičku varijabilnost i evolucione aspekte mikrosatelitskih lokusa.

Od početka svog naučno-istraživačkog rada značajan deo istraživanja D. Savić-Pavićević orijentisan je ka neuromišićnim i neurološkim bolestima uzrokovanim nestabilnim ekspanzijama mikrosatelitskih lokusa – dinamičnim mutacijama. Radovi 57, 122, 123 i 124 daju pregled osobina mikrosatelitskih lokusa i dinamičnih mutacija, kao i pregled molekularne genetike i molekularne patogeneze bolesti nestabilnih ekspanzija ponovaka. U okviru ove oblasti istraživanja D. Savić-Pavićević su najvećim delom fokusirana na ispitivanje miotoničnih distrofija. Razvijanje originalnih molekularno genetičkih metoda za detekciju i određivanje veličine ekspanzija povezanih sa miotoničnim distrofijama (radovi 20 i 87) predstavljalo je osnovu za ispitivanje različitih genetičkih i kliničkih aspekata ovih bolesti. Rezultati izučavanja mejotičke i mitotičke nestabilnosti mutacije povezane sa miotoničnom distrofijom tip 1 i genotip-fenotip korelacije predstavljene su u radovima 20, 37, 61, 62, 63 i 160, dok su rezultati epidemioloških i populaciono genetičkih studija za ovo oboljenje predstavljeni u radovima 34, 35, 36 i 41. Pregledni radovi 32 i 119 opisuju molekularno-genetičke karakteristike miotonične distrofije tip 1 sa posebnim osvrtom na algoritam genetičkog testiranja. Rad 20 (objavljen u Human Mutation) je zahvaljujući primeni originalno razvijene metode Small pool PCR-a bio jedan od prvih koji je ukazao da je veličina ekspanzije progenitornog alela važan modifikator starosne dobi kada se javljaju prvi simptomi kod bolesnika sa miotoničnom distrofijom tip1, što je kasnije postala opšte prihvaćena činjenica u opisivanju genotip-fenotip korelacije ove bolesti. U radovima 7, 12, 24, 25, 45 i 60 opisan je niz karakteristika miotonične distrofije tip 2, koja je nedovoljno istražen klinički entitet sa izuzetnom fenotipskom varijabilonošču, dok radovi 31, 54 i 59 opisuju slučajeve sa neobičnim fenotipom miotonične distrofije ili njenom retkom kosegregacijom sa miastenijom gravis i miotoničnom distrofijom tip 2. Istraživanja u oblasti dinamičnih mutacija obuhvatila su i populaciono genetičke studije mikrosatelitskih lokusa povezanih sa spinocerebelarnim ataksijama (radovi 38, 39, 40 i 161) i fenokopijama Hantingtonove bolesti (51, 55 i 56) u grupama bolesnika sa idiopatskim spinocerebelarnim ataksijama, Parkinsonovom bolešću, Hantingtonovom bolešću, kao i u opštoj populaciji Srbije. U radovima 42 i 43 predstavljena je hipoteza da je alel gena ataksin 1 sa 31 CAG ponovkom in trans faktor nestabilnosti ekspanzija povezanih sa mitoničnom distrofijom tip 1 i Hantingtonovom bolešću. Kao faktor rizika za razvoj HD-fenokopija identifikovana je i tačkasta varijanta Q7R u genu za saitohin (rad 53). U radu 19 predstavljeni su razultati genotipizacije mikrosatelitskih lokusa, uključujući i lokus povezan sa Hantingtonovom bolešću, iz uzoraka drevne DNK čoveka izolovane iz arheoloških ostataka starih 600 i 7000 godina sa područja Srbije. Na osnovu analize ponovljenih kodona za glutamin (CAG) u genu hantingtin kod različitih vrsta sisara, u radu 159 pretpostavljeno da je do ekspanzije ovih ponovaka došlo u evolucionoj liniji koja je vodila do čoveka i predstavljen je model koevolucije ponovljenih kodona za glutamin i nizvodnih ponovljenih kodona za prolin.

Radovi 4 i 5, u kojima je D. Savić-Pavićević učestvovala kao član multidisciplinarnih međunarodnih timova, opisuju dva nova klinička entiteta čiji su geni uzročnici otkriveni genomskim pristupima. Rad 4 (objavljen u Nature Genetics) opisuje gen HINT1 kao uzročnika aksonalnu neuropatiju sa neuromiotonijom. Rad 5 (objavljen u European Journal of Human Genetics) opisuje novu recesivnu varijantu c.107635C>T, p.(Gln35879Ter), u genu TTN kao najčešći uzrok distalnih miopatija u Srbiji. Fenotip bolesnika je najsličniji tibijalnoj mišićnoj distrofiji za koju se smatralo da je povezana samo sa dominantnim varijantama u genu TTN. Nakon rezultata predstavljenih u radu 5 i komplementarnih rezultata grupe iz Finske, opisani fenotip je nazvan recesivna distalna titinopatija sa

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početkom u ranom adultnom periodu. Istraživanja genetičke osnove retkih neuromišićnih i neuroloških bolesti, obuhvataju i identifikaciju i validaciju novih varijanti u genu GNB1 povezanih sa opštim kašnjenjem u razvoju (rad 3), ispitivanje korelacije genotipa i fenotipa kod naslednih neuropatija, epilepsija i Dišenove mišićne distrofije (radovi 15, 16, 46 i 58), ispitivanje genetičkih faktora koji modifikuju efekat uzročne mutacije spinalne mišićne atrofije (rad 26), genetičko-epidemiološke i populacione studije Retovog sindroma i hemohromatoze (radovi 11 i 33), i značaj integrativnog pristupa u dijagnostici neuromišićnih bolesti (rad 120).

Ispitivanja faktora rizika, njihovih interakcija i udruženih efekata na pokušaj samoubistva sa ciljem da se iznađu modeli koji mogu pomoći u identifikaciji psihijatrijskih bolesnika sa povećanim rizikom za pokušaj samoubistva obuhvataju studije asocijacija gena za editovanje RNK i gena serotoninskiog sistema, kao i studije interakcija ovih genetičkih faktora sa stresnim događajima tokom života (zlostavljenjem tokom detinjstva i akutnim stresnim događajima) (radovi 6, 10 i 21). Rad 6 (objavljen u World Journal of Biological Psychiatry) je prvi ukazao da su genetički determinisane razlike u procesu editovanja RNK povezane sa samoubilačkim ponašanjem, i zajedno sa radom 21 ističe značaj izučavanja udruženih i interaktivnih efekata genetičkih i sredinskih faktora na razvoj složenog fenotipa kao što je samoubilačko ponašanje. Radovi 2, 14, 44 i 50 ukazuju da varijabilnost mikrosatelitskih lokusa u genima eksprimiranim u centralnom nervnom sistemu, koji imaju potencijal da modulišu čitav niz bioloških procesa vezanih za funkcije mozga i ponašanje, može doprineti predispoziciji za razvoj shizofrenije.

Istraživanja genetičkih fakora rizika za razvoj i progresiju karcinoma prostate sa ciljem identifikacije novih bioloških markera koji su u korelaciji sa standardnim prognostičkim parametrima (serumskom vrednošću PSA, stadijumom primarnog tumora određenim sistemom TNM klasifikacije i Glison gradusom) obuhvataju studije genetičke asocijacije varijanti identifikovanih u studijama asocijacije na nivou celog genoma (radovi 28, 29, 47 i 48), genu NOS3 (rad 30), genima za neke miRNK (radovi 8 i 13) i genima za neke proteine RNK interferencije (rad 23), kao i meta analize za varijante u genima hsa-miR-146a i NOS3 i regionu 17q12 (radovi 9, 27 i 28). Prustup genetičkih studija asocijacije u identifikaciji genetičke osnove karcionoma prostate i pregled rezultata prethodno navedenih radova dati su u radu 1. Povezanost varijanti u genu NOS3 sa idiopatskim sterilitetom kod muškaraca prikazana je u radu 22.

U radovima 17 i 18 predstavljena je učestalost 8 Y-vezanih mikrosatelitskih lokusa i 14 autozomnih mikrosatelitskih lokusa za populaciju Srbije i Crne Gore, kao i parametri podobnosti njihovog korišćenja u humanoj DNK identifikaciji. Radovi 118, 157 i 158 opisuju značaj DNK analiza u utvrđivanju biološkog srodstva, pregled osnovnih pretpostavki upotrebe molekularne genetike u forenzici i metodološke pristupe u sakupljanju i analizi bioloških tragova. Svoje iskustvo u različitim analizama DNK, D. Savić Pavićević je primenila u genotipizaciji hrasta kitnjaka korišćenjem markera u hloroplastnoj DNK (rad 52).

Rad 49, objavljen povodom obeležavanja 60 godina od otkrića sekundarne strukture DNK, opisuje istorijska otkrića koja su omogućila postavljanje modela dvolančane zavojnice DNK. Nova saznanja o nekodirajućim molekulima RNK, koja su u postgenomskoj eri značajno izmenila shvatanja o genomu i regulaciji ekspresije gena u eukariotskim ćelijama opisana su u radu 121.

Rezultati koje D. Savić-Pavićević postiže, pored bazičnog imaju i aplikativan značaj u oblasti medicinske i forenzičke genetike. Dala je značajan doprinos u razvoju klinički primenjivih genetičkih testova za nasledne bolesti (uključujući i prenatalne analize) i razvoju primene DNK analiza u sudskim parničnim i krivičnim predmetima u Srbiji.

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Lepo je pomenuti da je poštovanje i zahvalnost svom mentoru prof. Stanki Romac iskazala kroz objavljen In Memoriam Professor Stanka Romac (1954-2015) (Arch Biol Sci. 2016;68(3):685-687).

4. IZBORNI USLOVI

4.1. Stručno-profesionalni doprinos

4.1.1. Predsednik ili član uređivačkog odbora naučnih časopisa ili zbornika radova u zemlji ili inostranstvu

Član Uređivačkog odbora Archives of Biological Science (2014–). Urednik po pozivu posebne sveske Biologia Serbica posvećene Prvom kongresu

molekularnih biologa Srbije sa međunarodnim učešćem (CoMBoS); 20-22. septembar 2017; Beograd, Srbija.

4.1.2. Recenzent u vodećim međunarodnim naučnim časopisima, ili recenzent međunarodnih ili nacionalnih naučnih projekata

Nakon izbora u zvanje vanredni profesor recenzirala je 12 radova kategorije M20 – videti 3.3, str. 39-40.

4.1.3. Predsednik ili član organizacionog ili naučnog odbora na naučnim skupovima nacionalnog ili međunarodnog nivoa

Član Naučnog odbora i član Organizacionog odbora Prvog kongresa molekularnih biologa Srbije sa međunarodnim učešćem (CoMBoS); 20-22. septembar 2017; Beograd, Srbija.

Član Naučnog odbora Conference on Structure and Dynamics of the Sarcomere; 2016 May 4-6; Belgrade, Serbia.

4.1.4. Predsednik ili član komisija za izradu završnih radova na akademskim osnovnim, master ili doktorskim studijamа

Član komisija za izradu 24 doktorske teze, 52 master rada i jednog specijalističkog rada na Univerzitetu u Beogradu-Biološkom fakultetu i jednog diplomskog i jednog master rada na Univerzitetu u Beogradu-Hemijskom fakultetu – videti 2.2, str. 3-13.

*** Član komisija za izradu 7 doktorskih teza, 4 magistarska rada, 15 master ili

diplomskih radova na Univerzitetu u Beogradu-Biološkom fakultetu – videti 2.2, str. 4-14.

4.1.5. Rukovodilac ili saradnik na domaćim ili međunarodnim naučnim projektima

Rukovodilac bilateralnog projekta sa Slovenijom (451-03-39/2016-09/15/01, 2016-2017) i nacionalnog projekta osnovnih istraživanja iz biologije (OI 173016, 2011-2016) – videti 3.3, str. 38-39.

Učesnik dva međunarodna projekta (COST Action BM1207 i PRACTICAL) i dva bilateralna projekta (451-03-3095/2014-09/44, 2014-2015) – videti 3.3, str. 38.

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*** Učesnik dva nacionalna projekta osnovnih istraživanja iz biologije (143013 – 2005-

2010, 1521 – 2000-2005) i jednog iz medicine (1988 – 2000-2005), i jednog strateškog nacionalnog projekta (S.6.35.75.0126, 1999-2000) – videti 3.3, str. 39.

4.1.6. Autor/koautor prihvaćenog patenta, tehničkog unapređenja ili inovacije

4.1.7. Pisma preporuke

4.2. Doprinos akademskoj i široj zajednici

4.2.1. Članstvo u stranim ili domaćim akademijama nauka, ili članstvo u stručnim ili naučnim asocijacijama u koje se član bira

Upravitelj fondacije "Stanka Romac" (FOSTAR) (2016–) Zamenik predsednika Srpskog društva za molekularnu biologiju (MolBioS) (2015–) Član Nadzornog odbora Srpske mreže za neuromišićne bolesti (NMD Serb-Net)

(2014–)

Sudski veštak, oblast biologija, uža specijalnost DNK veštačenja, forenzička genetika (Ministarstvo pravde R Srbije, rešenje 740-05-03494/210-03, 06.07.2011.) (2011–)

4.2.2. Predsednik ili član organa upravljanja, stručnog organa ili komisija na fakultetu ili univerzitetu u zemlji ili inostranstvu

V. d. rukovodilac Centra za humanu molekularnu genetiku, Univerzitet u Beogradu-Biološki fakultet (2016–)

Zamenik predsednika Saveta Univerziteta u Beogradu-Biološkog fakulteta (2015–) Član Komisije za obezbeđenje kvaliteta, Univerzitet u Beogradu-Biološki fakultet

(2014-2015, 2016–) Član Komisije za izbor najboljeg naučnog rada mladog istraživača, Univerzitet u

Beogradu-Biološki fakultet (2014, 2015, 2016) Član Programske komisije za program biologija i zaštita životne sredine Istraživačke

stanice Petnica (2015–) Rukovodilac modula Humana molekularna biologija (2012–), prethodno Humana

molekularna genetika (2010-2012), na master akademskim studijama Molekularne biologije i fiziologije, Univerzitet u Beogradu-Biološki fakultet u saradnji sa prof. G. Brajuškovićem

Član Programskog saveta doktorskog programa Molekularna biologija, Univerzitet u Beogradu-Biološki fakultet (2006–)

Član Komisije za upis na master akademske studije, Univerzitet u Beogradu-Biološki fakultet (2012–2015)

Pomoćnik rukovodioca za oblast molekularna dijagnostika i utvrđivanje očinstva, Centar za humanu molekularnu genetiku, Univerzitet u Beogradu-Biološki fakultet (2008-2015)

Član Komisija za izbor u nastavnička zvanja na Univerzitetu u Beogradu-Biološkom fakultetu (G. Brajušković – zvanje vanredni profesor, M. Keckarević Marković – zvanje docent, M. Kecmanović – zvanje docent, D. Keckarević – zvanje docent), i na Univerzitetu u Beogradu-Medicinskom fakultetu (O. Stojković – zvanje vanredni profesor, član sa matičnog fakulteta)

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Član Komisija za izbor u naučno-istraživačka zvanja na Univerzitetu u Beogradu-Biološkom fakultetu (J. Karanović – zvanje istraživač saradnik, M. Brkušanin – zvanje istraživač saradnik, J. Pešović – zvanje istraživač saradnik, Z. Nikolić – zvanje istraživač saradnik i naučni saradnik), Univerzitetu u Beogradu-Medicinskom fakultetu (S. Perić – zvanje naučni saradnik), Univerzitetu u Beogradu-Institutu za molekularnu genetiku i genetičko inženjerstvo (J. Popović – zvanje naučni saradnik, D. Drakulić – zvanje naučni saradnik, Natasa Kovačević Grujučić – zvanje naučni saradnik i viši naučni saradnik, M. Gvozdenov – zvanje naučni saradnik), Institutu za nuklearne nauke Vinča (T. Đurić – viši naučni saradnik, Lj. Stojković – zvanje naučni saradnik, B. Gemović – zvanje naučni saradnik, I. Kolić – istraživač saradnik)

4.2.3. Član nacionalnog saveta, stručnog, zakonodavnog ili drugog organa i komisije ministarstva

4.2.4. Učešće u nastavnim aktivnostima van studijskih programa visokoškolske ustanove (permanentno obrazovanje, kursevi u organizaciji profesionalnih udruženja i institucija, programi edukacije nastavnika) ili u aktivnostima popularizacije nauke

Osmislila i organizovala Prvu petničku školu molekularne biologije – PCR u biološkim i biomedicinskim istraživanjima; 02-07. oktobar 2016; Istraživačka stanica Petnica, Petnica, Srbija.

Savić-Pavićević D . Primena PCR-a u dijagnostici naslednih bolesti i utvrđivanju biološkog srodstva. Prezentovano na: Prva petnička škola molekularne biologije – PCR u biološkim i biomedicinskim istraživanjima; 02-07. oktobar 2016; Istraživačka stanica Petnica, Petnica, Srbija.

Savić-Pavićević D . RNK svet eukariotske ćelije. Prezentovano na: Akreditovani seminar MOLEKULARNA BIOLOGIJA – lakšim putem do funkcionalnog znanja; Zavod za unapređivanje obrazovanja i vaspitanja R Srbije; kataloški brojevi K890791-1 (2014/15), 892 (2015/16) i 618 (2016/17 i 2017/18).

Savić-Pavićević D . RNK svet eukariotske ćelije. Prezentovano na: Seminar Biologija, Istraživačka stanica Petnica, Petnica, Srbija, 13.02.2016.

Savić-Pavićević D . Genetički pristupi u terapiji distrofinopatija. Prezentovano na: Edukativni kurs Terapijske novine u dečijoj neurologiji. IX/XV Kongres neurologa Srbije sa međunarodnim učešćem; 14-16. novembar 2013; Beograd, Srbija.

Savić-Pavicević D . Potential of genetically designed therapies for neuromuscular disorders. Presented in: The 45th Annual General Meeting of European Alliance of Neuromuscular Disorders Associations(EAMDA); 2015 September 25-27; Belgrade, Serbia.

Kojic S, Rakocević-Stojanović V, Milić-Rašić V, Savić-Pavićević D. NMD-Serbnet. Prezentovano na: Nedelja borbe protiv distrofija (u organizaciji Saveza distrofičara Srbije); 04. jun 2015; Beograd, Srbija.

Savić-Pavićević D . Asocijacija polimorfizama u genima za editovanje RNK i genima serotoninskog sistema sa pokušajem samoubistva kod psihijatrijskih bolesnika. Prezentovano na: Dan genetičkih varijanti (u organizaciji Saveza studenata Biološkog fakulteta, Studentske organizacije Farmaceutskog fakulteta i Studentskog parlamenta Biološkog fakulteta); 03. april 2015; Beograd, Srbija.

*** Savić-Pavicević D . Medical Genetics in Serbia. Presented in: International Regional

Conference on Medical Genetics (organized by University Children’s Hospital); 2009 March 6-7; Belgrade, Serbia.

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Savić-Pavicević D . Primate Biological Materials – the Use of F2 Generation in Experiments – Contibution to the Discussion. Presented in: 1st International SLASA Workshop on Laboratory Animal Science in Serbia (organized by Serbian Laboratory Animal Science Association (SLASA) and Faculty of Biology, University of Belgrade); 2006 July 15; Belgrade, Serbia.

4.2.5. Domaće i/ili međunarodne nagrade i priznanja u razvoju obrazovanja i nauke

Najbolji poster na Genomics of Rare Diseases Serbordisinn & 2014 Golden Helix Symposium; 2014 October 31-November 1; Belgrade, Serbia. (Pešović J, Perić S, Brkušanin N, Mandić M, Brajušković G, Romac S, Rakočević Stojanović V, Savić Pavićević D. PCR-based Southern blot for detection of DM2 expansions).

*** Apsolutno prvo mesto za najbolju tehnološku inovaciju u Srbiji u kategoriji

„Potencijali“. Ministarstvo za nauku i tehnološki razvoj R Srbije i Privredna komora Srbije; 2008. Tim: Romac S, Savić-Pavićević D, Brajušković G, Janković Pavlović N i Todorović S.

Prvo mesto za najbolju tehnološku inovaciju u Srbiji za oblast medicina i genetika u kategoriji „Potencijali“. Ministarstvo za nauku i tehnološki razvoj R Srbije i Privredna komora Srbije; 2008. Tim: Romac S, Savić-Pavićević D, Brajušković G, Janković Pavlović N i Todorović S.

Prva (A1) nagrada za naučna dostignuća u 2002-2003. godini. Ministarstvo za nauku i zaštitu životne sredine R Srbije (2004).

4.2.6. Socijalne veštine (posedovanje komunikacionih sposobnosti, sposobnosti za prezentaciju, sposobnosti za timski rad i vođenje tima)

Od 2010. godine vodi istraživačku grupu Centra za humanu molekularnu genetiku koja se bavi molekularnom genetikom neuromišićnih i psihijatrijskih bolesti

Saradnje u okviru projekata i studija na kojima radi: Dugogodišnja saradnja u okviru projekata: Prof. Vidosava Rakočević-Stojanović i

Prof. Zorica Stević (Klinika za neurologiju), Prof. Vedrana Milić-Rašić (Klinika za neurologiju i psihijatriju za decu i omladinu), Doc. Maja Ivković (Klinika za psihijatriju), Univerzitet u Beogradu-Medicinski fakultet

Dugogodišnja saradnja u okviru projekata: Prof. Pavle Anđus (Centar za lasersku mikroskopiju), Univerzitet u Beogradu-Biološki fakultet

Saradnja u okviru bilateralnih projekata: Prof. Boris Rogelj i Doc. Tomaž Bratkovič, University of Ljubljana, Ljubljana, Slovenija, Faculty of Pharmacy

Saradnje u okviru studije o poreklu i istorijskom putu mutacije povezane sa miotoničnom distrofijom tip 2: Prof. Laura Ranum (University of Florida, Gainesville, FL, USA, Center for NeuroGenetics), Jancsi Radvanszky, PhD (Institute for Clinical and Translational Research, Biomedical Research Centre, Slovak Academy of Sciences, Bratislava, Slovakia), Zuzana Musova, PhD (Charles University 2nd Faculty of Medicine and University Hospital Motol, Department of Biology and Medical Genetics, Prague, Czech Republic), Kristýna Stehlíková, PhD (University Hospital Brno, Centre of Molecular Biology and Gene Therapy, Brno, Czech Republic), Kyriaki Kekou, PhD (University of Athens, "Aghia Sophia Children's Hospital", Department of Medical Genetics), Prof. Lea Leonardis (Institute of Clinical Neurophysiology, University Medical Center Ljubljana, Ljubljana, Slovenia)

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Saradnja u okviru studije o distalnim miopatijama: Prof. Hanns Lochmüller (Newcastle University, Newcastle upon Tyne, United Kingdom, The John Walton Muscular Dystrophy Research Centre and Institute of Genetic Medicine).

Saradnja u okviru studije o Retovom sindromu: Prof. Kristina Clain, Ana Westenberger, PhD (University of Lübeck, Lübeck, Germany, Institute of Neurogenetics)

4.2.7. Sposobnost pisanja projektne dokumentacije i dobijanja domaćih i međunarodnih naučnih i stručnih projekata

Dobila je finansiranje za bilateralni projekat sa Slovenijom (451-03-39/2016-09/15/01 – 2016-2017), nacionalni projekat osnovnih istraživanja (OI173016 – 2011-2016) i prihvaćena je u COST akciji (BM1207). Aktivno je učestvovala u pisanju predloga svih projekata na kojima učestvuje od 2005. godine – videti 3.3, str. 38-39.

4.3. Saradnja sa drugim visokoškolskim, naučno-istraživačkim ustanovama, odnosno ustanovama kulture ili umetnosti u zemlji i inostranstvu

4.3.1. Postdoktorsko usavršavanje ili studijski boravci u inostranstvu

4.3.2. Rukovođenje ili učešće u međunarodnim naučnim ili stručnim projekatima ili studijama

Networking towards Clinical Application of Antisense Mediated Exon Skipping. Biomedicine and Molecular Biosciences COST Action – BM1207. Period: 2013-2017. Chair of the Action: A. Aartsma-Rus. Management Committee Substitute, Serbia: D. Savić-Pavićević.

PRACTICAL (Study group: SNPs and prostate cancer risk in Serbian population/ PROSTATSERBIA). Funded by: The Institute of Cancer Research: Royal Cancer Hospital, London, UK. Principal Investigator: G. Brajušković.

4.3.3. Radno angažovanje u nastavi ili komisijama na drugim visokoškolskim ili naučnoistraživačkim ustanovama u zemlji ili inostranstvu, ili zvanje gostujućeg profesora, ili istraživača

Član Komisija za izbor u naučno-istraživačka zvanja na Univerzitetu u Beogradu-Medicinskom fakultetu (S. Perić – zvanje naučni saradnik), Univerzitetu u Beogradu-Institutu za molekularnu genetiku i genetičko inženjerstvo (J. Popović – zvanje naučni saradnik, D. Drakulić – zvanje naučni saradnik, Natasa Kovačević Grujučić – zvanje naučni saradnik i viši naučni saradnik, M. Gvozdenov – zvanje naučni saradnik), Institutu za biološka istraživanja Siniša Stanković (M. Sinadinovič – istraživač pripravnik), Institutu za nuklearne nauke Vinča (T. Đurić – viši naučni saradnik, Lj. Stojković – zvanje naučni saradnik, B. Gemović – zvanje naučni saradnik, I. Kolić – istraživač saradnik).

Član Komisije za procenu aktuelnosti teme doktorske disertacije Analiza genotipa kod osoba sa Charcot Marie Tooth neuropatijom. Univerzitet u Beogradu-Medicinski fakultet. Kandidat dr Jelena Nikodinović Glumac, MSc. Mentor prof. V. Milić Rašić.

4.3.4. Rukovođenje ili članstvo u organu profesionalnog udruženja ili organizaciji nacionalnog ili međunarodnog nivoa

Srpsko društvo za molekularnu biologiju (MolBioS) – zamenik predsednika (2015–), učestvovala u osnivanju

Srpska mreža za neuromišićne bolesti (NMDSerb-Net) – član Nadzornog odbora (2014–), učestvovala u osnivanju

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Srpski savet za mozak (SSM) – učestvovala u osnivanju Društvo genetičara Srbije, sekcija Medicinska genetika European Society of Human Genetics (ESHG) Društvo za neuronauke Srbije (DNS) Federation of European Neurosciences (FENS) Srpsko biološko društvo (SBD)

4.3.5. Učešće u programima razmene nastavnika i studenata

4.3.6. Učešće u izradi i sprovođenju zajedničkih studijskih programa

4.3.7. Predavanja po pozivu na univerzitetima u zemlji i inostranstvu

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5. ZAKLJUČAK I MIŠLJENJE KOMISIJE

Na osnovu analize nastavno-pedagoškog i naučno-istraživačkog rada dr Dušanke Savić-Pavićević, vanrednog profesora na Katedri za biohemiju i molekularnu biologiju Biološkog fakulteta Univerziteta u Beogradu, kao i na osnovu ličnog dugogodišnjeg poznavanja kandidatkinje i njenog rada Komisija sa zadovoljstvom konstatuje da je kandidatkinja ostvarila veoma uspešnu nastavničku karijeru, kao i izuzetno plodnu naučnu karijeru, o čemu jasno govore podaci izneti u ovom referatu.

Dr Dušanka Savić-Pavićević je tokom svoje nastavničke karijere dala značajan doprinos razvoju i reformama studijskih programa molekularne biologije na svim nivoima studija. Aktivnim promišljanjem, vrednim angažovanjem i kreativnim predlozima, samostalno ili u saradnji sa kolegama, učestvovala je u kreiranju i reformisanju nastavnih planova ne samo pojedinačnih predmeta već i čitavih studijskih programa osnovnih, master i doktorskih akademskih studija. Na osnovnim akademskim studijama uvela je i osmislila praktične vežbe iz predmeta Molekularna biologija eukariota, a kasnije je silabus ovog predmeta dopunila najnovijim saznanjima o RNK svetu eukariotskih ćelija. Inicirala je uvođenje predmeta Molekularna biologija ćelije. Aktivno radi na poboljšavanju i inoviranju programa predmeta Osnovi molekularne biologije i prvi je autor udžbenika Molekularna biologija 1. Inicirala je uvođenje i učestvovala u kreiranju programa modula Humana molekularna biologija na master studijama Molekularne biologije i fiziologije. Imala je važnu ulogu u osmišljavanju prvog kurikuluma Doktorskog studijskog programa Molekularna biologija. Osmislila je predmet Molekularna biologija neuromišićnih i psihijatrijskih bolesti na doktorskom modulu Molekularna biologija eukariota. Ocenivši je najvišim ocenama u svojim anketama, studenti su očigledno prepoznali dr Dušanku Savić Pavićević kao inovativnog i posvećenog nastavnika koji uvek pruža najnovije i verodostojne informacije, podstičući njihovu motivaciju i kreativnost. Značajan doprinos nastavi na Biološkom fakultetu dr Dušanka Savić-Pavićević dala je i kao mentor velikog broja doktorskih i master studenata, i član Komisija za pregled, ocenu i odbranu velikog broja doktorskih disertacija, master radova, magistarskih teza i diplomskih radova. Posebno je vredno pažnje njeno učešće u cuklusnom projektu Geni i genom u organizaciji Srpske akademije nauka i umetnosti, u okviru kojeg je održala predavanje i u prigodnom zborniku radova objavila poglavlje pod naslovom „Anatomija i fiziologija genoma – šta smo naučili u genomskoj eri?”. Ovo poglavlje pruža pregled najnovijih saznanja i koncepata o strukturi i funkciji genoma, tako da predstavlja dragoceni doprinos molekularno biološkoj literaturi na srpskom jeziku. Još jedan značajan aspekt pedagoškog rada dr Dušanke Savić-Pavićević je njeno angažovanje na stručnom usavršavanju nastavnika biologije u srednjim i osnovnim školama, negovanju nastavnog i naučnog podmlatka i popularizaciji nauke.

Oblast naučno-istraživačkog rada dr Dušanke Savić-Pavićević je humana molekularna genetika. Predmet njenih istraživanja je molekularno genetička osnova, populaciona genetika i genetička epidemiologija retkih bolesti, kao što su neuromišićne i neurološke bolesti, ali i čestih bolesti, kao što su psihijatrijska oboljenja i karcinom prostate. Kandidatkinja je autor ili koautor ukupno 161 bibliografske jedinice, od kojih je 56 kategorije M20 (2 M21a, 16 M21, 24 M22, 13 M23 i 1 M24). U periodu nakon izbora u zvanje vanrednog profesora 2010. godine objavila je 29 radova kategorije M20 (2 M21a, 10 M21, 12 M22 i 5 M23), od kojih je 12 (1 M21a, 5 M21, 5 M22 i 1 M23) objavila nakon reizbora u zvanje vanredni profesor u oktobru 2015. godine. Radovi kategorije M21a koje je objavila nakon izbora u zvanje vanrednog profesora objavljeni su u najprestižnijim međunarodnim časopisima u oblasti humane molekularne genetike, kao što su Nature Genetics i Human Molecular Genetics.

Istraživanja dr Dušanke Savić-Pavićević iz oblasti dinamičnih mutacija i bolesti nestabilnih ekspanzija ponovaka, pre svega miotoničnih distrofija, značajno su doprinela boljem razumevanju molekularne i populacione genetike, kao i epidemiologije ovih bolesti. Neki od njenih radova često su citirani u međunarodnim knjigama i monografijama, kao i revijskim radovima iz ove oblasti. Kao član međunarodnih timova dr Dušanka Savić-

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Pavićević učestvovala je u otkriću gena uzročnika, uspostaviće se, dva nova klinička entiteta: aksonalne neuropatije sa neuromiotonijom i recesivne distalne titinopatije sa početkom u ranom adultnom periodu. Njena kasnije započeta istraživanja iz molekularne genetike psihijatrijskih bolesti prva su ukazala da su genetički determinisane razlike u procesu editovanja RNK povezane sa samoubilačkim ponašanjem. Ovi rezultati su bili osnova za njena nedavno započeta istraživanja o povezanosti editovanja RNK u mozgu i odgovora na sredinske stimuluse, kojima je zašla u tek formiranu oblast epitranskriptomike. Radovi dr Dušanke Savić-Pavićević citirani su 277 puta u časopisima koji imaju impakt faktor, od kojih je gotovo polovina u časopisima kategorija M21a i M21. Pored toga, citirani su još 40 puta u međunarodnim i on-line monografijama, i 19 puta u stranim doktorskim disertacijama.

Rezultati koje dr Dušanka Savić-Pavićević postiže, pored bazičnog imaju i aplikativan značaj u oblasti medicinske i forenzičke genetike. Kandidatkinja je dala značajan doprinos razvoju klinički primenjivih genetičkih testova za nasledne bolesti koji se mogu primeniti i prenatalno, kao i razvoju primene DNK analiza u sudskim parničnim i krivičnim postupcima u našoj zemlji.

Ceneći kvalitet nastavno-pedagoškog i naučno-istraživačkog rada dr Dušanke Savić Pavićević i imajući u vidu značaj nastavnih programa koje realizuje, kao i doprinos razvoju mladih naučnih i nastavnih kadrova, Komisija ima izuzetnu čast i zadovoljstvo da predloži Izbornom veću Biološkog fakulteta Univerziteta u Beogradu da prihvati ovaj izveštaj i utvrdi predlog Veću naučnih oblasti prirodnih nauka Univerziteta u Beogradu da se dr Dušanka Savić-Pavićević izabere u zvanje redovnog profesora za užu naučnu oblast Biohemija i molekularna biologija na Katedri za biohemiju i molekularnu biologiju Instituta za fiziologiju i biohemiju Univerziteta u Beogradu – Biološkog fakulteta.

U Beogradu, 18.07.2017.

____________________________________Prof. Gordana Matić

Univerzitet u Beogradu – Biološki fakultet;Univerzitet u Beogradu – Institut za biološka

Istraživanja “Siniša Stanković”

____________________________________Akademik Milena Stevanović

Srpska akademija nauka i umetnosti;Univerzitet u Beogradu – Biološki fakultet;

Univerzitet u Beogradu – Institut za molekularnugenetiku i genetičko inženjerstvo

____________________________________Prof. Pavle Anđus

Univerzitet u Beogradu – Biološki fakultet

____________________________________Prof. Đorđe Fira

Univerzitet u Beogradu – Biološki fakultet

____________________________________Prof. Vidosava Rakočević-Stojanović

Univerzitet u Beogradu – Medicinski fakultet

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