diclofenac research
DESCRIPTION
Diclofenac compound Research contains : 1- Introduction about The Pharmacological Class. 2- Name of the drug (IUPAC, generic and trade names). 3- Structure of the drug (drawn by Chemsketch program). 4- Synthesis of the drug (drawn by Chemsketch program). 5- Spectral data of the drug (UV, IR, NMR and Mass). 6- Uses, Side effects and Contraindications.TRANSCRIPT
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Research OnNon Steroidal Anti-Inflammatory Drugs
(NSAIDs)
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Content :
1- Introduction about The Pharmacological Class.
2- Name of the drug (IUPAC, generic and trade names).
3- Structure of the drug (drawn by Chemsketch program).
4- Synthesis of the drug (drawn by Chemsketch program).
5- Spectral data of the drug (UV, IR, NMR and Mass).
6- Uses, Side effects and Contraindications.
7- A table describing the role of each student in the group in fulfilling the project.
Diclofenac Research
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The Pharmacological Class
• Diclofenac belongs to the class of acetic acid derivatives and related substances of non-steroidal anti-inflammatory and antirheumatic products.
• This medicine works by reducing substances in the body that cause pain and inflammation.
• Diclofenac is used to treat pain or inflammation caused by arthritis or ankylosing spondylitis.
Diclofenac Research
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IUPAC, Generic & Trade Names
• IUPAC Name: 2-(2,6-dichloranilino) phenylacetic acid.
• Generic Name: Diclofenac Sodium, Diclofenac Potassium &
Diclofenac epolamine.
• Trade Name: Voltaren, Cataflam, Flector & Anuva
Diclofenac Research
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Diclofenac Research
Diclofenac Sodium
Diclofenac Potassium
Diclofenac epolamineDiclofenac (as free acid)
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Structure of Drug
Diclofenac Research
Diclofenac_3D
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Synthesis of the drug
Diclofenac Research
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Spectral Data of the Drug
Diclofenac Research
IR
Diclofenac Sodium
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Diclofenac Research
Spectral Data of the Drug
UVSpectrum of Diclofenac in NaOH
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Diclofenac Research
Spectral Data of the Drug
NMR
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Diclofenac Research
Spectral Data of the Drug
Mass
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Diclofenac Research
• Diclofenac is used to treat pain, inflammatory disorders, and dysmenorrhea.
• Diclofenac is used commonly to treat mild to moderate postoperative or post-traumatic pain, in particular when inflammation is also present, and is effective against menstrual pain and endometriosis.
Uses
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Side Effects
• This medicine may cause life-threatening heart or circulation problems such as heart attack or stroke, especially if you use it long term.
• This medicine may also cause serious effects on the stomach or intestines, including bleeding or perforation (forming of a hole).
Diclofenac Research
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Contraindication
• Do not use diclofenac just before or after heart bypass surgery (coronary artery bypass graft, or CABG).
• Diclofenac is contraindicated in hypersensitivity, active peptic ulcer, moderate to severe hepatic disease and in pregnancy.
• Those with Alcohol abuse, Colitis, Crohn's disease, diverticulitis, gastric ulcer, Diabetes mellitus, Hemorrhoids, Hepatitis, renal disease, Rectal irritation.
Diclofenac Research
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