developing and sustaining an ultrasound-guided peripheral ... · lww/aenj tme200073 april 29, 2010...
TRANSCRIPT
LWW/AENJ TME200073 April 29, 2010 19:10 Char Count= 0
Advanced Emergency Nursing JournalVol. 32, No. 2, pp. 173–188
Copyright c! 2010 Wolters Kluwer Health | Lippincott Williams & Wilkins
Developing and Sustaining anUltrasound-Guided PeripheralIntravenous Access Program forEmergency Nurses
Ann White, MSN, RN, CCNS, CEN, CPENFernando Lopez, MDPhillip Stone, RN
AbstractUltrasonography use in the emergency department (ED) has been well established. The use of ultra-sonography that falls into the traditional practice of the emergency nurse is peripheral intravenous(IV) access. Benefits of using ultrasonography for peripheral IV access include decreasing patientthroughput, cost reduction, decreasing complications, increased patient and emergency medicinephysician satisfaction, and emergency nurse autonomy. Review of the literature demonstrates nodiscernable differences in ability and efficacy with ultrasound (US)-guided peripheral IV access whencomparing data from studies about emergency medicine physicians, certified registered nursesanesthetists, emergency department technicians, physician assistants, and emergency registerednurses. In 2006, Duke University Hospital Emergency Department started a US-Guided PeripheralIV Access program for emergency nurses. Similar patient populations have been observed and thesame types of complications have been encountered as described in the literature. Future goalsinclude perfecting nurses’ vein selection, and to study skill mastery with US-guided peripheral IV ac-cess. Key words: emergency nurse, peripheral intravenous (IV) access, ultrasonography, ultrasound(US), US-guided peripheral IV
THE utility of ultrasonography in theemergency department (ED) has beenwell established in the last decade.
Emergency medicine (EM) physicians utilize
Author Affiliations: Duke University Hospital Depart-ment of Advanced Clinical Practice and Duke Univer-sity School of Nursing (Ms White), Duke UniversityMedical Center (Dr Lopez), and Duke University Hospi-tal Emergency Department (Mr Stone), Durham, NorthCarolina.
Supplemental digital content is available for this arti-cle. Direct URL citations appear in the printed text andare provided in the HTML and PDF versions of this ar-ticle on the journal’s Web site (www.AENJournal.com).
Corresponding Author: Ann White, MSN, RN, CCNS,CEN, CPEN, Duke University Hospital, DUMC 3677,Durham, NC 27710 ([email protected]).
ultrasonography for diagnostic purposes toevaluate multiple organ systems in differentclinical scenarios. It is also used for centraland peripheral venous catheter access. Theuse of EM ultrasonography that falls into thetraditional practice of the emergency nurseis peripheral intravenous (IV) access. Eventhe most experienced emergency nurse mayhave difficulty obtaining IV access in patientswith conditions such as injection drug use,obesity, chronic illness, hypovolemia, shock,vasculopathy, and extremes of age. These pa-tients lack easy access to peripheral venoussites using the traditional techniques of di-rect visualization, anatomic landmarks, pal-pation, and trial-and-error blind cannulation.
173
LWW/AENJ TME200073 April 29, 2010 19:10 Char Count= 0
174 Advanced Emergency Nursing Journal
Figure 1. DUH ED nurse, P. Stone, using ultra-sonography to start IV. Reprinted with permissionof Sonosite Inc.
Although these patients require timely pe-ripheral venous access, their condition maynot be so acute as to require emergent cen-tral venous or intraosseous access.
An evolving option for peripheral IV ac-cess is the utilization of ultrasonography bythe emergency nurse (Figure 1). This optionis employed after traditional techniques havefailed. This technique can also be used by thenurse for the initial IV attempt for patientswho have a history or suspicion of difficult IVaccess based on medical history.
BENEFITS
There are several benefits of using ultrasonog-raphy:
• decreasing patient throughput time anddelays in diagnosis and treatment due toless time spent in obtaining venous ac-cess,
• cost reduction by avoiding critical caretime and use of expensive equipmentfor central catheter insertion, at thesame time eliminating exposure to iatro-genic complications such as pneumotho-rax and bloodstream infection, which in-crease mortality, hospital length of stay,and healthcare costs, and
• decreasing complications of traditionalinsertion that include pain, arterial punc-ture, nerve damage, and paresthesias(Aponte et al., 2007; Blaivas, Brannam,
& Fernandez, 2003; Blaivas & Lyon,2006; Bauman, Braude, & Crandall, 2009;Brannam, Blaivas, Lyon, & Flake, 2004;Witting, Schenkel, Lawner, & Euerle, inpress).
Additional benefits include• increased patient comfort and satisfac-
tion,• increased EM physician satisfaction due
to sustained productivity because of lessinterruptions to work flow to completea routine procedure normally accom-plished by nurses, and
• increased emergency nurse autonomy(Bauman et al., 2009; Blaivas, 2005;Costantino, Parikh, Satz, & Fojtik, 2005;Mills, Liebmann, Stone, & Frazee, 2007;Stein, Cole, & Kramer, 2004).
The use of ultrasonography is advantageousbecause there are no biological effects and nouse of ionizing radiation; ultrasonography alsomeasures blood flow and can provide real-time vascular imaging (Aponte et al., 2007).
REVIEW OF THE LITERATURE
The literature provides varied informationabout formal research findings and clinical ex-perience with the use of ultrasonography forperipheral IV access. Six studies published be-tween 1999 and 2009 describe the successrate in difficult peripheral IV access using ul-trasonography by EM physicians (Costantinoet al., 2005; Keyes, Franzee, Snoey, Simon,& Christy, 1999; Mills et al., 2007; Steinet al., 2004; Stein, George, River, Hebig, &McDermott, 2009; Witting et al., in press).In ED patients with difficult peripheral IV ac-cess, researchers from all studies except one(Stein et al., 2009) concluded that US-guidedvein cannulation was safe and rapid and had ahigh success rate. In addition, the majority ofcannulations were accomplished with one at-tempt (n = 387; Costantino et al., 2005; Keyeset al., 1999; Mills et al., 2007; Stein et al.,2004; Witting et al., in press). Physicians re-ported untoward outcomes such as mechani-cal, infectious, and thrombotic complications(Table 1). In contrast to the five other studies,Stein et al. (2009) concluded that US-guided
LWW/AENJ TME200073 April 29, 2010 19:10 Char Count= 0
April–June 2010 ! Vol. 32, No. 2 Ultrasound-Guided Peripheral IV Access Program 175
Tab
le1.
Inci
denc
eof
com
plic
atio
nsfr
omul
tras
ound
-gui
ded
per
iphe
ralI
Vac
cess
byEM
phy
sici
ans
Co
stan
tin
oM
ills
Wit
tin
get
al.
Stei
nK
eyes
etal
.,19
99et
al.,
2005
etal
.,20
07in
pre
sset
al.,
2009
Co
mp
lica
tio
nty
pe
(N=
100)
(N=
60)
(N=
25)
(N=
180)
(N=
59)
Mec
hani
cal
8%In
filtr
ated
orfe
llou
t0
4%1%
Pare
sthe
sias
0A
rter
ialb
lood
flow
thro
ugh
the
cath
eter
,US
evid
ence
ofar
teri
alp
unct
ure,
hem
atom
afo
rmat
ion,
par
esth
esia
s,an
dve
nous
infil
trat
ion
2%B
rach
iala
rter
ial
pun
ctur
e
1%Pa
rest
hesi
adu
eto
cont
act
wit
hbr
achi
alne
rve
2%ot
her
Infe
ctio
usN
otm
easu
red
Not
mea
sure
d0
Not
mea
sure
d0
Eryt
hem
a,p
ain,
edem
aco
nsis
tent
wit
hca
thet
er-a
ssoc
iate
dce
llulit
isor
phl
ebit
is,o
rp
osit
ive
cath
eter
-tip
cult
ure
Thr
ombo
tic
Not
mea
sure
dN
otm
easu
red
0N
otm
easu
red
0A
nycl
inic
alor
US
evid
ence
ofup
per
-ext
rem
ity
veno
usth
rom
bosi
s
Not
e:U
S=
ultr
asou
nd.
Dat
afr
om“U
ltra
soun
d-G
uide
dB
rach
ial
and
Bas
ilica
Vein
Can
nula
tion
inEm
erge
ncy
Dep
artm
ent
Pati
ents
Wit
hD
iffi
cult
Intr
aven
ous
Acc
ess,
”by
L.K
eyes
,B
.Fr
anze
e,E.
Snoe
y,B
.Si
mon
,an
dD
.C
hris
ty,
1999
,A
nn
als
ofE
mer
gen
cyM
edic
ine,
34,
pp
.71
1–71
4;“U
ltra
sono
grap
hy-G
uide
dPe
rip
hera
lIn
trav
enou
sA
cces
sVe
rsus
Trad
itio
nalA
pp
roac
hes
inPa
tien
tsW
ith
Dif
ficu
ltIn
trav
enou
sA
cces
s,”
byT.
Cos
tant
ino,
A.
Pari
kh,
W.
Satz
,an
dJ.
Fojt
ik,
2005
,A
nn
als
ofE
mer
gen
cyM
edic
ine,
46,
pp
.456
–461
;“U
ltra
sono
grap
hica
llyG
uide
dIn
sert
ion
ofa
15-c
mC
athe
ter
Into
the
Dee
pB
rach
ialo
rB
asili
cVe
inin
Pati
ents
Wit
hD
iffi
cult
Intr
aven
ous
Acc
ess,
”by
C.M
ills,
O.L
iebm
ann,
M.S
tone
,and
B.F
raze
e,20
07,A
nn
als
ofE
mer
gen
cyM
edic
ine,
50,p
p.6
8–72
;“Ef
fect
sof
Vein
Wid
than
dD
epth
onU
ltra
soun
d-G
uide
dPe
rip
hera
lIV
Succ
ess
Rat
es,”
byM
.Wit
ting
,S.S
chen
kel,
B.L
awne
r,an
dB
.Eue
rle,
B,i
np
ress
,Th
eJo
urn
al
ofE
mer
gen
cyM
edic
ine,
doi:1
0.10
16/j
.jem
erm
ed.2
009.
01.0
03.“
Ult
raso
nogr
aphi
cally
Gui
ded
Peri
phe
ral
Intr
aven
ous
Can
nula
tion
inEm
erge
ncy
Dep
artm
ent
Pati
ents
Wit
hD
iffi
cult
Intr
aven
ous
Acc
ess:
AR
ando
miz
edTr
ial,”
byJ.
Stei
n,B
.G
eorg
e,G
.R
iver
,A
.H
ebig
,and
D.M
cDer
mot
t,20
09,A
cade
mic
Em
erge
ncy
Med
icin
e,54
,pp
.33–
40.
LWW/AENJ TME200073 April 29, 2010 19:10 Char Count= 0
176 Advanced Emergency Nursing Journal
peripheral IV cannulation did not decreasethe number of attempts, time to successfulcatheterization, nor did it improve patient sat-isfaction and suggested that there is no supe-riority of this technique.
The literature has also described othertypes of clinicians using ultrasonography tostart peripheral IVs. In 2007, Aponte et al.described successful use of ultrasonographyby certified registered nurse anesthetists. Re-searchers randomized subjects to a traditionalgroup and a US-guided group and measuredtime to successful cannulation on first at-tempt and number of attempts per subject.White, Sturges, Barton, Battaglia, and Mc-Cowan (2007) and Bauman et al. (2009) de-scribed similar studies with ED techniciansthat also showed that the use of ultrasonog-raphy increases the success rate of periph-eral IV placement. In 2009, Witting et al. stud-ied the effects of vein width and depth inUS-guided peripheral IV success rates. Threepercent of the attempts studied were per-formed by physician assistants, and 1% ofthe attempts were performed by a registerednurse.
Only three observational, descriptive stud-ies have been published about specific emer-gency nurse experience with US-guided pe-ripheral IV access. Two are from the samehealthcare institution, with analysis solelyfrom the EM physician’s perspective. Thesetwo studies use the same sample of emer-gency nurses. The 2004 study (Brannamet al.) actually measured the utility of nurses,using US in the clinical setting, and the2006 study (Blaivas & Lyon) measured theperception of technical difficulty by thesame nurses with the same patient sample.In 2007, Chinnock, Thornton, and Hendeystudied predictors of success in emergencynurse-performed US-guided cannulation. Thisis the only study measuring complicationsfrom cannulation by an emergency nurse. Incomparing the studies measuring certifiedregistered nurse anesthetists’, emergencytechnicians’, physician assistants’, and emer-gency nurses’ success with US-guided periph-eral IV access with studies measuring EM
physicians’ success with US-guided peripheralIV access, there are no discernable differencesin ability and efficacy (Table 2).
DUKE UNIVERSITY HOSPITAL EMERGENCYDEPARTMENT’S US-GUIDEDPERIPHERAL IV ACCESS
Program for Emergency Nurses
The motivation to develop emergency nursecompetency in US-guided peripheral IV ac-cess began as a grassroots effort in 2006 bystaff nurses. The nurses observed the utilityof the technology when used by EM physi-cians after they were unsuccessful in obtain-ing IV access with the traditional approachand sought information about ultrasonogra-phy for peripheral access from their EM physi-cian colleagues.
A small number of nurses were instructedon the technique during actual applicationwith a real patient by the EM physiciansand requested to be able to use this newknowledge independently when attemptingto start IVs on patients. After consulting theState Nursing Practice Act and securing sup-port from ED and organizational leadership,a program was developed to train the emer-gency nurses in US-guided venous cannu-lation. Organizational experts who assistedwith the training included an ultrasonogra-phy fellowship-trained EM attending physi-cian, clinicians from the IV therapy depart-ment who use bedside ultrasonography forperipherally inserted central catheters, anda representative from SonoSite Inc. (Both-ell, WA, manufacturer of the portable USmachine).
Senior staff nurses are selected to be trainedon this advanced skill. This approach is usedas a retention strategy to recognize the nurse’sexperience and as an appeal to their requestfor advanced education and responsibility.The role is highlighted as an advanced clin-ical role in the department and somethingthat less-experienced nurses can strive for,as novice nurses, especially new graduatenurses, need to remain focused on improving
LWW/AENJ TME200073 April 29, 2010 19:10 Char Count= 0
April–June 2010 ! Vol. 32, No. 2 Ultrasound-Guided Peripheral IV Access Program 177
Tab
le2.
Com
par
ison
ofab
ility
wit
hU
S-gu
ided
per
iphe
ral
IVac
cess
bydi
ffer
ent
clin
icia
ns(A
pon
teet
al.,
2007
;B
aum
anet
al.,
2009
;B
rann
amet
al.,
2004
;Cos
tant
ino
etal
.,20
05;K
eyes
etal
.,19
99;M
ills
etal
.,20
07;S
tein
etal
.,20
04;S
tein
etal
.,20
09;W
hite
etal
.,20
07;
Wit
ting
etal
.,in
pre
ss)
Sub
ject
sw
ith
succ
essf
ul
Tim
eto
succ
essf
ul
US-
guid
edIV
Nu
mb
ero
fTy
pe
of
Nu
mb
ero
fU
S-gu
ided
can
nu
lati
on
on
can
nu
lati
on
wh
ensu
cces
sfu
lat
tem
pts
per
Inci
den
ceo
fcl
inic
ian
/stu
dy
sub
ject
sfi
rst
atte
mp
to
nfi
rst
atte
mp
tsu
bje
ctco
mp
lica
tio
ns
EM
atte
nd
ing
ph
ysic
ian
Stei
net
al.(
2009
)28
Not
rep
orte
dse
par
atel
y39
±52
(Mea
sure
din
min
utes
from
enro
llmen
tto
bloo
dre
turn
;co
uld
use
one-
ortw
o-p
erso
nte
chni
que
and
itw
asno
tre
por
ted
whi
chon
ew
asus
ed)
2±
1Se
eTa
ble
1
EM
atte
nd
ing
ph
ysic
ian
and
resi
den
tp
hys
icia
nK
eyes
etal
.(19
99)
100
73%
77±
129
(Mea
sure
din
seco
nds
whe
ntr
ansd
ucer
pla
ced
onsk
inan
dve
inca
nnul
ated
;use
dtw
o-p
erso
nte
chni
que,
tim
est
arte
daf
ter
clea
ning
)
Not
mea
sure
dSe
eTa
ble
1
Stei
net
al.(
2004
)15
86%
Not
mea
sure
d1.
3N
otm
easu
red
Cos
tant
ino
etal
.(2
005)
3997
%4
±5.
6(M
easu
red
inm
inut
esfr
omne
edle
pun
ctur
eto
vein
cann
ulat
ed)
1.7
±0.
7Se
eTa
ble
1
Mill
set
al.(
2007
)25
61%
3±
5(M
easu
red
inm
inut
esw
hen
tran
sduc
erp
lace
don
skin
and
vein
cann
ulat
ed;c
ould
use
one
ortw
o-p
erso
nte
chni
que
and
itw
asno
tre
por
ted
whi
chon
ew
asus
ed)
1.52
See
Tabl
e1
(con
tin
ues
)
LWW/AENJ TME200073 April 29, 2010 19:10 Char Count= 0
178 Advanced Emergency Nursing Journal
Tab
le2.
Com
par
ison
ofab
ility
wit
hU
S-gu
ided
per
iphe
ral
IVac
cess
bydi
ffer
ent
clin
icia
ns(A
pon
teet
al.,
2007
;B
aum
anet
al.,
2009
;B
rann
amet
al.,
2004
;Cos
tant
ino
etal
.,20
05;K
eyes
etal
.,19
99;M
ills
etal
.,20
07;S
tein
etal
.,20
04;S
tein
etal
.,20
09;W
hite
etal
.,20
07;
Wit
ting
etal
.,in
pre
ss)
(Con
tin
ued
)
Sub
ject
sw
ith
succ
essf
ul
Tim
eto
succ
essf
ul
US-
guid
edIV
Nu
mb
ero
fTy
pe
of
Nu
mb
ero
fU
S-gu
ided
can
nu
lati
on
on
can
nu
lati
on
wh
ensu
cces
sfu
lat
tem
pts
per
Inci
den
ceo
fcl
inic
ian
/stu
dy
sub
ject
sfi
rst
atte
mp
to
nfi
rst
atte
mp
tsu
bje
ctco
mp
lica
tio
ns
EM
atte
nd
ing
ph
ysic
ian
and
resi
den
tp
hys
icia
n(9
5%o
fat
tem
pts
),p
hys
icia
nas
sist
ant
(3%
of
atte
mp
ts),
regi
ster
edn
urs
e(1
%o
fat
tem
pts
)W
itti
nget
al.i
np
ress
)18
056
%N
otm
easu
red
1.32
See
Tabl
e1
Cer
tifi
edre
gist
ered
nu
rse
anes
thet
ist
Ap
onte
etal
.(20
07)
1974
%18
7.3
±22
8.3
(Mea
sure
din
seco
nds
whe
ntr
ansd
ucer
pla
ced
onsk
inan
dve
inca
nnul
ated
;use
don
e-p
erso
nte
chni
que,
tim
est
arte
dbe
fore
clea
ning
)
1.4
±0.
7N
otre
por
ted
Em
erge
ncy
dep
artm
ent
tech
nic
ian
(EM
tech
nic
ian
-par
amed
ico
rE
Mte
chn
icia
n-i
nte
rmed
iate
)W
hite
etal
.(20
07)
4575
.6%
Not
mea
sure
d1.
29±
0.56
0B
aum
anet
al.(
2009
)75
80.5
%26
.8(M
easu
red
inm
inut
esw
hen
tran
sduc
erp
lace
don
skin
tove
inca
nnul
ated
;use
don
e-p
erso
nte
chni
que)
1.6
±0.
79.
8%ar
teri
alp
unct
ures
wit
hno
dist
alva
scul
arco
mp
rom
ise,
blee
ding
stop
ped
wit
h5-
min
com
pre
ssio
n;he
mat
oma
29.3
%;n
erve
pai
n2.
4%E
mer
gen
cyn
urs
eB
rann
amet
al.
(200
4)32
187
%N
otm
easu
red
Not
mea
sure
d1.
2%,a
llar
teri
alp
unct
ures
Chi
nnoc
k,T
horn
ton,
&H
endy
;200
7
119
44%
Not
mea
sure
dN
otm
easu
red
4.2%
arte
rial
;2.5
%ar
mnu
mbn
ess;
6.7%
seve
rep
ain;
allr
esol
ved
duri
ngED
stay
Not
e:EM
=em
erge
ncy
med
icin
e,IV
=in
trav
enou
s,U
S=
ultr
asou
nd.
LWW/AENJ TME200073 April 29, 2010 19:10 Char Count= 0
April–June 2010 ! Vol. 32, No. 2 Ultrasound-Guided Peripheral IV Access Program 179
Table 3. Summary of ultrasound didactic training
Ultrasound physics—30 min Highlighting potential physiological effects affecting safety:ultrasonography enhances inflammatory response; and itcan heat soft tissue
Operation of US machine—30 min Screen settings, gain, field depth, and image optimizationHow to scan—1 hr Use of ultrasonographic gel, transducer probe selection,
transverse or longitudinal beam, pressure of probe, needletip location, and anatomy
US-guided IV procedure—1 hr Preparation, transducer probe orientation, equipmentpositioning, scout scan, asepsis, needle angle, evaluation,pearls and pitfalls
Note: IV = intravenous; US = ultrasound.
their basic psychomotor skill with traditionalIV access techniques. Another benefit of lim-iting the number of nurses who are trained touse ultrasonography is that their proficiencywill develop and remain because their oppor-tunity to use ultrasonography will not be di-luted as it might if all nurses were trained.This approach to prevent decay in skill levelis also described in the literature (Chinnock,Thornton, & Hendey, 2007).
The training consists of a 3-hour initial train-ing session that includes didactic informa-tion, simulation, and hands-on practice. Ta-ble 3 summarizes major concepts of the ini-tial training. Table 4 lists the behavioral ob-jectives used to evaluate competency withthe skill. The initial skill acquisition revolvesaround the nurse being able to manipulate thetransducer probe to view the vessels from alongitudinal (long axis) or transverse (shortaxis) approach (Figures 2–4). Although stud-ies demonstrate that novice ultrasonographyusers obtain vascular access faster with ashort-axis approach and it seems to be thepreferred approach for cannulation becausethe blood vessel is easier to see and lessalignment needs to be performed, we en-courage skill development, mainly hand–eyecoordination, using both positions (Blaivaset al., 2003; Brannam, Fernandez, & Blaivas,2003).
In the long-axis approach, the entire length ofthe needle can be tracked on the ultra ma-
chine screen as it enters the blood vessel allow-ing greater visualization of the needle-tip loca-tion, whereas with the short-axis approach, thisis not the case, because only a portion of theneedle can be tracked as it passes through theUS beam under the transducer probe (Blaivas etal., 2003). If the nurse prefers to gain IV accesswith the short-axis approach, we emphasize thetechnique with the US transducer probe of fan-ning off the end of the needle tip to visualize thebevel end. This deforms the target vessel priorto cannulation and then upon insertion, position-ing the US transducer probe with the long-axisview for definitive confirmation of location andeffective function potential (Supplemental DigitalContent, Videos demonstrating this are availableat http://links.lww.com/AENJ/A1 and http://links.lww.com/AENJ/A2, see videos 1 and 2).
After the initial session, nurses are requiredto be observed starting peripheral IVs withultrasonography by a core group of proctors.At least 10 proctored attempts were selectedas the benchmark for competency beforethe emergency nurse can perform ultrasonog-raphy independently. This number was de-termined by the ultrasonography fellowship-trained EM attending physician who acts asa medical director for the program, which isfacilitated and coordinated by the ED clini-cal nurse specialist (CNS). The core proctorsare limited to the ultrasonography fellowship-trained EM attending physician, the ED CNS,and three other trained nurses selected by theED CNS on the basis of their overall technical
LWW/AENJ TME200073 April 29, 2010 19:10 Char Count= 0
180 Advanced Emergency Nursing Journal
Table 4. Performance criteria to evaluate competency for ultrasound-guided peripheral IVinsertion
Competency Performance criteria
Assessment of patient Assesses patient for need to utilize US-guided intravenous accessReviews most recent history and physical, medication history, and
allergiesConfirms patient identification armband
Planning for procedure Collects necessary supplies, personal protective equipment, and sets upas needed
Explains procedure to patientTeaches patient symptoms to report during procedure
Patient safety Differentiates and identifies arteries versus veins using ultrasonographyUtilizes appropriate infection-control measures to reduce risk of invasive
line infectionDetermines the depth of the target vein utilizing depth scale on US
device and selects the appropriate length IV catheter (1.16 in. forstandard, 1.88 in. for deeper target veins)
Removes tourniquet promptly when indicatedMonitors line patency and infusion to detect signs and symptoms of
infiltrationEvaluation Confirms blood return, easy flush, and absence of swelling or tenderness
at siteDocuments use of ultrasonography for IV placement, catheter size,
length, location, and site conditionLabels IV site with insertion date, catheter size, and whether deep
brachial vein was usedReevaluates site frequently for signs of infiltrationEvaluates patient’s response to procedure
Note: IV = intravenous, US = ultrasound.
skill and ability to teach and mentor others.Once the proctored insertions are completed,a signed document confirming the compe-tencies that were observed is placed in thenurse’s personnel file and an announcementrecognizing the nurse’s accomplishment issent out electronically to all ED staff. Also, thenurse’s name is added to a reference that isposted in the clinical area that lists the namesof the nurses that ED staff can consult whenIV access using the traditional approach hasfailed. The process of consulting one of thesenurses first, before involving an EM physicianto start the IV, is stressed.
The objective in using a small core groupof proctors is to allow a greater chancefor consistency in technique, mainly focus-
ing on aseptic technique and how to avoidarterial puncture when venous cannulationis the goal. The cited literature inconsis-tently mentions in a detailed fashion infectionprevention technique used while insertingUS-guided venous catheters. For example,Mills et al. (2007) state that the catheterwas inserted by EM physicians with unster-ile ultrasonographic gel and unsterile glovesand Bauman et al. (2009) mention using asemisterile technique with a nonsterile trans-ducer probe. With a major focus on reduc-ing bloodstream infections, and also becauseblood cultures are frequently obtained withthe IV insertion, Duke’s procedure includesthe use of sterile ultrasonographic gel andcovering the probe with a sterile transparent
LWW/AENJ TME200073 April 29, 2010 19:10 Char Count= 0
April–June 2010 ! Vol. 32, No. 2 Ultrasound-Guided Peripheral IV Access Program 181
Figure 2. First two images show transducer place-ment for short-axis (transverse) view includinghow image appears on ultrasound machine screen.Last two images show transducer placement forlong-axis (longitudinal) view including how imageappears on ultrasound machine screen. Used withpermission from SonoSite® Inc.
dressing before placing it on the cleansed skinover the preselected puncture site.
Along with instruction on peripheral ve-nous access, which includes recognizing thedifference between a vein and an artery,
Figure 3. A cannulated vein using the short-axis(transverse) view, needle appears as bright, whitepoint in center of vein at a depth of approxi-mately 1 cm. Bright white dots are depth indicatorsspaced at 1 cm increments.
Figure 4. A cannulated vein using the long-axis(longitudinal) view, cannula appears as long whiteline in middle of vein at a depth of approximately 1cm. Bright white dots are depth indicators spacedat 1 cm increments.
nurses are taught how to use this same tech-nology for arterial puncture to obtain bloodsampling for blood gas analysis. Another appli-cation of ultrasonography is fetal heart rate vi-sualization. Nurses are taught how to visualizefetal heart rate after hand-held Doppler assess-ment is unsuccessful. These two applicationsare infrequently used compared with the usefor establishing IV access. However, anecdo-tally, nurses seem to grasp the technique andconcept quite readily.
Since 2006, the training class has been of-fered four times. At present, 13 nurses (ap-proximately 10% of registered nurse full-timeequivalents with an equal distribution on theday and night shift are trained to performUS-guided peripheral IV access independentlyand approximately 10 nurses are currently inthe process of being proctored.
We have observed similar patient popu-lations described in two studies that high-lighted poor peripheral vasculature with scle-rosis and scar tissue from chronic injectiondrug use followed by chemotherapy, obesity,and hypotension (Keyes et al., 1999; Millset al., 2007) as the most prevalent patienttypes who present with difficult peripheralIV access. Two chronic conditions also men-tioned in the literature that we found in ourclinical setting who are common candidatesfor ultrasonography as the initial modality
LWW/AENJ TME200073 April 29, 2010 19:10 Char Count= 0
182 Advanced Emergency Nursing Journal
for IV insertions are patients with sickle celldisease and chronic renal failure (Aponteet al., 2007; Brannam et al., 2004; Costantinoet al., 2005; Witting et al., in press).
Blaivas and Lyon (2006) also noted many pa-tients with chronic medical conditions whoexperience acute exacerbations and frequentvisits to the ED, attempt to avoid blind IV at-tempts and request immediate use of ultra-sonography when blood sampling or IV ther-apy is required. It has become common sincethe start of our ultrasonography program thatpatients with chronic conditions, who visitthe ED frequently, ask for their IV to be startedinitially with the US technique. The ability toprovide this US-guided service has resultedin increased patient comfort, satisfaction, andimproved rapport with the healthcare team.
We have also encountered the same typesof complications described in the literatureabout ED technicians by Bauman et al. (2009)and emergency nurses by Brannam et al.(2004) and Chinnock, Thornton, and Hendey(2007). These authors cited the occurrenceof arterial puncture during cannulation. Thiscomplication was also noted in the stud-ies with EM physicians (Costantino et al.,2005; Keyes et al., 1999; Mills et al., 2007;Witting et al., in press). Arteries may be dif-ficult to identify and differentiate from veins.This can be due to low systolic pressure orpoor arterial wall tone. We have outlined forthe US-trained nurses a decision-making pro-cess (Table 5) to confirm whether the IV iswhere they want it to be.
First, the tendency is to compress vesselsquickly and completely flat. Sometimes, pul-sations can be obscured by complete com-pression. Try slowing the compression rateand hold the vessel at a partially com-pressed position and look for subtle pulsa-tions. This may require observation for sev-eral seconds (a video of this is available athttp://links.lww.com/AENJ/A3, see video 3).Second, if cannulation has already occurred,confirm the absence of pulsations by aspi-rating blood halfway or less into the exten-sion tubing and observe for pulsatory fluc-tuations in the column of blood, possibly
Table 5. Decision-making process to confirmIV location
Slow the compression rate and hold thevessel at a partially compressed positionand look for subtle pulsations. This mayrequire observation for several seconds.
If cannulation has already occurred, confirmabsence of pulsations by aspirating bloodhalfway or less into the extension tubingand observe for pulsatory fluctuations inthe column of blood, possibly very subtle,similar to those observed in a sphygmomanometer.
Following cannulation of the vessel, tryconfirming the position in the vessel byusing a longitudinal view. Apply mildcompression in that view to confirm thatthere are no pulsations. Pulsations wouldindicate arterial cannulation.
The color Doppler signal feature can be usedto discern catheter location and is definedas red representing blood flow toward thetransducer (arterial) and bluerepresenting blood flow away from thetransducer (venous).
An arterial blood gas can be analyzed toevaluate the values for arterial blood.
very subtle, similar to those observed in asphygmomanometer. Following cannulationof the vessel, try confirming the catheter po-sition in the vessel by using a longitudinalview. Apply mild compression in that viewto confirm that there are no pulsations. Pul-sations would indicate arterial cannulation.The color Doppler signal feature can alsobe used to discern catheter location and isdefined as red representing blood flow to-ward the transducer (arterial) and blue repre-senting blood flow away from the transducer(venous; video available at http://links.lww.com/AENJ/A4, see video 4). Also, an arterialblood gas can be analyzed to evaluate the val-ues for arterial blood.
Anecdotal reports of inconsistent longevityof the catheter function after insertion havebeen common. This phenomenon seems tobe correlated with experience and skill of the
LWW/AENJ TME200073 April 29, 2010 19:10 Char Count= 0
April–June 2010 ! Vol. 32, No. 2 Ultrasound-Guided Peripheral IV Access Program 183
Figure 5. Nurse-provided venous access using ultrasonography data collection form, Duke University Hos-pital emergency department.
US-trained nurse. Failed cutaneous puncturesare cited as common in the literature (Baumanet al., 2009; Mills et al., 2007; Witting et al.,in press). In 2009, Witting et al. studied vein
width and depth on the probability of suc-cess in US-guided IV insertion. The resultsof this study showed that success rates arehigher in larger veins (!0.4 cm) and veins at
LWW/AENJ TME200073 April 29, 2010 19:10 Char Count= 0
184 Advanced Emergency Nursing Journal
moderate depth (0.3–1.5 cm; Witting et al., inpress). The researchers suggested that mod-erate depth is more successful because moreshallow veins do not allow enough distance tovisualize the needle approaching the target re-quiring a shallower needle angle and veins atgreater depths have inadequate needle lengthto pass into the vein (Witting et al., in press).
A problem frequently cited in the literatureis the proximity of the US-guided IV site to thebiceps muscle and tendon and the occasionalpractice of securing the IV tubing across theantecubital fossa when that site is used, re-sulting in more tip movement during arm ma-nipulation, movement of the catheter in andout of the vessel, and extravasation when ashorter catheter is used (Bauman et al., 2009;Blaivas, 2005; Keyes et al., 1999; Wittinget al., in press). To mitigate these problems,this information was shared with the currentUS-trained nurses. The use of longer catheters(1.88 in.) exclusively for US-guided IV accessis taught. We will be periodically validatingthat the US-trained nurses are adept at mea-suring width and depth and we will be stress-ing avoidance of veins with unfavorable char-acteristics (too small, shallow, or deep) moreprominently in future training for nurses newto the skill to ensure greater longevity of IVfunction.
Data collection for performance-improvement purposes has recently started.The US-trained nurses complete the formafter each patient encounter, documentingpatient characteristics, degree of patient satis-faction, and information about the access andpatient outcomes elucidating the potentialbenefits and complications of US guidance inIV access (Figure 5). The choice was made notto approach this data collection as researchbut rather as quality improvement becausea research process would have requiredobtaining informed consent from the patientbefore using ultrasonography. It was felt thatconsenting the patient as a research subjectwould delay IV access and patients mightthink that the use of ultrasonography wasexperimental as opposed to an establishedtool to accomplish a standard procedure.
FUTURE RESEARCH
The literature already clearly identifies the pa-tient characteristics that support ultrasonog-raphy use and the benefits and risks. Whatis not identified clearly in the literature istime and number of patient encounters re-quired by the ultrasonographer to feel profi-cient. The literature provides anecdotal infor-mation about how different clinician types ac-quired their skill with starting IVs with ultra-sonography (Table 6).
The research question that needs to be an-swered is: How does the ultrasonographer de-velop skill mastery with US-guided peripheralIV access? Are the 10 proctored insertionsan adequate number to measure skill mas-tery? Plans are under way to study emergencynurses’ skill mastery with the technique byanalyzing how many cannulations it takes fora nurse to feel proficient with US-guided pe-ripheral IV access and what other types of re-sources contributed to that perception of skillmastery.
CONCLUSION
Developing a program to train emergencynurses in US-guided venous cannulation isviable, easy, and safe. Future goals includeincreasing the number of nurses trained toperform US-guided venous cannulation, per-fecting the nurses’ vein selection decisionsto increase longevity of the IV, and to studyhow nurses develop their skill mastery withUS-guided peripheral IV access. We are alsoconsidering exploring training nurses to useultrasonography for bladder scanning to im-pact incidence of urinary tract infections fromunwarranted urinary catheter insertion in theED.
Overall, senior nurses are acknowledgedfor the benefit their skills add to the effi-ciency of the care team and patient through-put. The EM physicians appreciate the con-tribution these nurses’ independent ability tomanage this technology provides to patientlength of stay and the physicians’ produc-tivity due to less interruptions for what is
LWW/AENJ TME200073 April 29, 2010 19:10 Char Count= 0
April–June 2010 ! Vol. 32, No. 2 Ultrasound-Guided Peripheral IV Access Program 185
Tab
le6.
Skill
acqu
isit
ion
stat
emen
tsin
the
liter
atur
e(A
pon
teet
al.,
2007
;B
aum
anet
al.,
2009
;B
laiv
aset
al.,
2003
;B
laiv
aset
al.,
2006
;B
rann
amet
al.,
2003
;Bra
nnam
etal
.,20
04;C
osta
ntin
oet
al.,
2005
;Key
eset
al.,
1999
;Ste
inet
al.,
2004
;Ste
inet
al.,
2009
;Wit
ting
etal
.,in
pre
ss)
Ref
eren
ceSa
mp
lety
pe
Stat
emen
tab
ou
tU
SIV
-sk
ill
acq
uis
itio
n
Key
eset
al.(
1999
)EM
atte
ndin
gp
hysi
cian
and
resi
dent
phy
sici
an
EDp
atie
nts
EMat
tend
ing
phy
sici
anor
seni
orre
side
nts
who
had
US
exp
erie
nce
and
unde
rwen
tbr
ief
trai
ning
inid
enti
ficat
ion
ofde
epbr
achi
alan
dba
silic
vein
Bla
ivas
etal
.(20
03)
Sim
ulat
edin
anim
ate
arm
mod
elSt
udie
dno
vice
US
user
sEM
resi
dent
phy
sici
ans
30-m
inut
edi
dact
icse
ssio
n,th
enim
med
iate
lyat
tem
pte
dU
SIV
acce
ssw
ith
100%
succ
ess
rate
Litt
lein
vest
igat
ion
rega
rdin
gte
achi
ngm
odel
sfo
rU
SIV
acce
ssha
vebe
enre
por
ted
Ifef
fici
ency
isth
ego
al,t
each
shor
t-axi
sap
pro
ach
first
beca
use
ityi
elds
fast
est
acce
ssB
rann
amet
al.(
2003
)Si
mul
ated
inan
imat
ear
mm
odel
Stud
ied
novi
ceU
Sus
ers
EMre
side
ntp
hysi
cian
s30
-min
ute
dida
ctic
sess
ion,
then
imm
edia
tely
atte
mp
ted
US
IVac
cess
eith
erus
ing
SAor
LAap
pro
ach.
Mea
nti
me
toSA
was
2.36
min
and
LAw
as5.
02m
indi
ffer
ence
stat
isti
cally
sign
ifica
nt(p
=0.
03).
Mea
ndi
ffic
ulty
scor
esfo
rSA
and
LAw
ere
3.99
and
5.86
(dif
fere
nce
not
stat
isti
cally
sign
ifica
nt)
Nov
ice
US
user
sob
tain
vasc
ular
acce
ssm
uch
fast
erus
ing
SAap
pro
ach
Bra
nnam
etal
.(20
04)
EDp
atie
nts
Non
eof
the
nurs
esha
dus
edU
Sp
revi
ousl
yfo
ran
yap
plic
atio
nB
laiv
aset
al.(
2006
)B
oth
stud
ies
used
sam
esa
mp
leof
emer
genc
ynu
rses
Perf
orm
edU
Saf
ter
45-m
inut
edi
dact
icse
ssio
nw
ith
hand
s-on
pra
ctic
ew
ith
sim
ulat
edin
anim
ate
arm
mod
el89
%su
cces
sra
tew
ith
SAte
chni
que,
85%
succ
ess
rate
wit
hLA
tech
niqu
e(d
iffe
renc
eno
tst
atis
tica
llysi
gnifi
cant
)N
urse
sre
por
ted
decr
ease
inp
erce
ived
diff
icul
tyin
obta
inin
gIV
acce
ssby
US
desp
ite
the
use
ofte
chno
logy
bein
gne
w—
fam
iliar
izat
ion
wit
heq
uip
men
tan
dte
chni
que
for
both
visu
aliz
atio
nan
dca
nnul
atio
noc
curr
edqu
ickl
yan
dea
sily
(con
tin
ues
)
LWW/AENJ TME200073 April 29, 2010 19:10 Char Count= 0
186 Advanced Emergency Nursing Journal
Tab
le6.
Skill
acqu
isit
ion
stat
emen
tsin
the
liter
atur
e(A
pon
teet
al.,
2007
;B
aum
anet
al.,
2009
;B
laiv
aset
al.,
2003
;B
laiv
aset
al.,
2006
;B
rann
amet
al.,
2003
;Bra
nnam
etal
.,20
04;C
osta
ntin
oet
al.,
2005
;Key
eset
al.,
1999
;Ste
inet
al.,
2004
;Ste
inet
al.,
2009
;Wit
ting
etal
.,in
pre
ss)
(Con
tin
ued
)
Ref
eren
ceSa
mp
lety
pe
Stat
emen
tab
ou
tU
SIV
-sk
ill
acq
uis
itio
n
The
mos
tdi
ffic
ult
skill
was
dep
ende
nce
oney
e–ha
ndco
ordi
nati
on(v
isua
lizin
gth
eve
inon
the
US
mac
hine
scre
enan
dm
aint
aini
ngp
rop
ertr
ansd
ucer
pro
bep
lace
men
tw
ith
one
hand
and
cann
ulat
ion
wit
hth
eot
her)
Stei
net
al.(
2004
)EM
Att
endi
ngPh
ysic
ians
EDp
atie
nts
The
nurs
ew
ould
seek
the
assi
stan
ceof
ap
hysi
cian
com
fort
able
wit
hU
S-gu
ided
per
iphe
ralI
Vca
nnul
atio
n.C
osta
ntin
oet
al.(
2005
)EM
atte
ndin
gp
hysi
cian
and
resi
dent
phy
sici
an
EDp
atie
nts
Phys
icia
nsw
ere
fam
iliar
wit
hU
Sfr
omre
side
ncy
trai
ning
—3-
wee
kED
rota
tion
wit
hso
lefo
cus
ondo
ing
US,
15hr
ofdi
dact
icle
ctur
ean
d10
0em
erge
ncy
US
scan
sp
erfo
rmed
Mor
eex
peri
ence
dw
asde
fined
asp
hysi
cian
who
pla
ced
mor
eth
an10
pre
viou
sU
S-gu
ided
IVca
thet
ers
wit
hex
per
ienc
era
ngin
gfr
omno
pre
viou
sU
S-gu
ided
IVac
cess
exp
erie
nce
to50
orm
ore
pla
cem
ents
Ap
onte
etal
.(20
07)
Cer
tifie
dre
gist
ered
nurs
ean
esth
etis
ts
Peri
oper
ativ
ep
atie
nts
Cer
tifie
dre
gist
ered
nurs
ean
esth
etis
tsp
laci
ngth
eca
thet
ers
wer
ew
ell
exp
erie
nced
inth
eus
eof
US
(3ye
ars’
exp
erie
nce)
.Op
erat
ors
wit
ha
rang
eof
exp
erie
nce
inU
Ssh
ould
bein
clud
edin
futu
rein
vest
igat
ions
Chi
nnoc
k,T
horn
ton,
&H
ende
y;20
07Em
erge
ncy
Nur
ses
EDp
atie
nts
Perf
orm
edU
Saf
ter
90m
inut
edi
dact
icse
ssio
nw
ith
hand
son
pra
ctic
ew
ith
sim
ulat
edin
anim
ate
arm
mod
el.T
rain
edon
lyin
shor
t-axi
sap
pro
ach.
Wor
k-sh
ifts
wit
hle
ssU
S-tr
aine
dnu
rses
had
mor
eca
nnul
atio
nop
por
tuni
ties
wit
hm
odes
tim
pro
vem
ent
insk
ill.I
nclu
sion
crit
eria
limit
edp
atie
ntse
lect
ion
tow
orst
acce
ssp
atie
nts
mak
ing
nurs
esw
ait
mon
ths
inbe
twee
nat
tem
pts
lead
ing
tola
ckof
conf
iden
cean
dde
cay
insk
ill.P
ossi
ble
solu
tion
wou
ldbe
totr
ain
alln
urse
san
dto
dooc
casi
onal
refr
eshe
rsto
mai
ntai
nsk
ill.
Wit
ting
etal
.(in
pre
ss)
EMat
tend
ing
and
resi
dent
phy
sici
ans
(95%
ofat
tem
pts
),p
hysi
cian
assi
stan
ts(3
%of
atte
mp
ts),
and
regi
ster
ednu
rses
(1%
ofat
tem
pts
)
EDp
atie
nts
Succ
ess
rate
low
est
ingr
oup
wit
hle
ssth
an20
pri
orat
tem
pts
and
pla
teau
saf
ter
20at
tem
pts
(con
tin
ues
)
LWW/AENJ TME200073 April 29, 2010 19:10 Char Count= 0
April–June 2010 ! Vol. 32, No. 2 Ultrasound-Guided Peripheral IV Access Program 187
Tab
le6.
Skill
acqu
isit
ion
stat
emen
tsin
the
liter
atur
e(A
pon
teet
al.,
2007
;B
aum
anet
al.,
2009
;B
laiv
aset
al.,
2003
;B
laiv
aset
al.,
2006
;B
rann
amet
al.,
2003
;Bra
nnam
etal
.,20
04;C
osta
ntin
oet
al.,
2005
;Key
eset
al.,
1999
;Ste
inet
al.,
2004
;Ste
inet
al.,
2009
;Wit
ting
etal
.,in
pre
ss)
(Con
tin
ued
)
Ref
eren
ceSa
mp
lety
pe
Stat
emen
tab
ou
tU
SIV
-sk
ill
acq
uis
itio
n
Bau
man
etal
.(20
09)
EDte
chni
cian
sED
pat
ient
sPe
rfor
med
US
afte
r1-
hour
dida
ctic
sess
ion
wit
hha
nds-
onp
ract
ice
wit
hsi
mul
ated
inan
imat
ear
mm
odel
Del
ayin
tim
eto
acce
ssm
ayha
vebe
ena
resu
ltof
EDte
chni
cian
s’in
exp
erie
nce
wit
hth
eU
Sm
achi
nean
dth
ete
chni
que
orlo
cati
nga
suit
able
site
.Pre
viou
sst
udie
sus
edre
side
nts
and
EMat
tend
ing
phy
sici
ans
wit
hco
nsid
erab
leU
Sex
per
ienc
e.St
ein
etal
.(20
09)
EDp
atie
nts
12cr
eden
tial
edin
US
acco
rdin
gto
Am
eric
anC
olle
geof
Emer
genc
yPh
ysic
ians
guid
elin
es,8
inp
roce
ssof
cred
enti
alin
gan
dha
dre
ceiv
eda
16-h
our
intr
oduc
tory
cour
se.A
llp
hysi
cian
sp
ract
iced
per
form
ing
US-
guid
edIV
sfo
r6
mon
ths
trai
ning
per
iod
pri
orto
stud
y.G
oalw
asno
tto
asse
ssw
heth
era
subg
roup
ofhi
ghly
trai
ned
phy
sici
ans
coul
dp
erfo
rmth
iste
chni
que
bett
er.F
urth
erst
udy
isre
com
men
ded
tode
term
ine
whe
ther
ther
eis
ap
hysi
cian
trai
ning
thre
shol
dat
whi
chp
atie
nts
are
likel
yto
bene
fitm
ore
cons
iste
ntly
Not
e:ED
=em
erge
ncy
dep
artm
ent,
EM=
emer
genc
ym
edic
ine,
IV=
intr
aven
ous,
LA=
long
axis
,SA
=sh
ort
axis
,US
=ul
tras
ound
.
LWW/AENJ TME200073 April 29, 2010 19:10 Char Count= 0
188 Advanced Emergency Nursing Journal
perceived as a nurse’s procedure. Patientsbenefit from decreased exposure to risk fromcentral venous access and, as cited in the liter-ature, experience satisfaction during their EDvisit with this nurse-provided intervention.
REFERENCES
Aponte, H., Acosta, S., Rigamonti, D., Sylvia, B., Austin, P.,& Samolitis, T. (2007). The use of ultrasound for place-ment of intravenous catheters. American Associationof Nurse Anesthetists Journal, 75, 212–216.
Bauman, M., Braude, D., & Crandall, C. (2009).Ultrasound-guidance vs. standard technique indifficult vascular access patients by ED technicians.American Journal of Emergency Medicine, 27,135–140.
Blaivas, M. (2005). Ultrasound-guided peripheral IV inser-tion in the ED. American Journal of Nursing, 105,54–57.
Blaivas, M., Brannam, L., & Fernandez, E. (2003).Short-axis versus long-axis approaches for teachingultrasound-guided vascular access on a new inanimatemodel. Academic Emergency Medicine, 10, 1307–1311.
Blaivas, M., & Lyon, M. (2006). The effect of ultrasoundguidance on the perceived difficulty of emergencynurse-obtained peripheral IV access. The Journal ofEmergency Medicine, 31, 407–410.
Brannam, L., Blaivas, M., Lyon, M., & Flake, M. (2004).Emergency nurses’ utilization of ultrasound guid-ance for placement of peripheral intravenous linesin difficult-access patients. Academic EmergencyMedicine, 11, 1361–1363.
Brannam, L., Fernandez, E., & Blaivas, M. (2003). Shortaxis versus long axis approaches for teaching ultra-sound guided vascular access [Abstract]. AcademicEmergency Medicine, 10, 572–573.
Chinnock, B., Thornton, S., & Hendey, G. (2007). Predic-tors of success in nurse–performed ultrasound–guidedcannulation. The Journal of Emergency Medicine, 33,401–405.
Costantino, T., Parikh, A., Satz, W., & Fojtik, J. (2005).Ultrasonography-guided peripheral intravenous ac-cess versus traditional approaches in patients withdifficult intravenous access. Annals of EmergencyMedicine, 46, 456–461.
Keyes, L., Franzee, B., Snoey, E., Simon, B., & Christy, D.(1999). Ultrasound-guided brachial and basilica veincannulation in emergency department patients withdifficult intravenous access. Annals of EmergencyMedicine, 34, 711–714.
Mills, C., Liebmann, O., Stone, M., & Frazee, B. (2007).Ultrasonographically guided insertion of a 15-cmcatheter into the deep brachial or basilic vein in pa-tients with difficult intravenous access. Annals ofEmergency Medicine, 50, 68–72.
Stein, J., Cole, W., & Kramer, N. (2004). Ultrasound-guided peripheral intravenous cannulation in emer-gency department patients with difficult IV access[Abstract]. Academic Emergency Medicine, 11, 581–582.
Stein, J., George, B., River, G., Hebig, A., & McDermott,D. (2009). Ultrasonographically guided peripheral in-travenous cannulation in emergency department pa-tients with difficult intravenous access: A randomizedtrial. Annals of Emergency Medicine, 54, 33–40.
White, S., Sturges, Z., Barton, E., Battaglia, D., & Mc-Cowan C. (2007). Ultrasound-guided peripheral ve-nous access by emergency medical technicians in pa-tients with difficult access [Abstract]. Annals of Emer-gency Medicine (Suppl.) 50, S85.
Witting, M., Schenkel, S., Lawner, B., & Euerle, B. (inpress). Effects of vein width and depth on ultrasound-guided peripheral IV success rates. The Journal ofEmergency Medicine. doi:10.1016/j.jemermed.2009.01.003.