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Department of Biology Honours Info Session 4 Nov, 2019

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Page 1: Department of Biology · 2019-11-05 · 1. Cryobiology of sturgeon germplasm 5. Effect of yolk and lipid quality on visual development, larval growth and survival--Zebrafish 2. Xenotransplantation

Department of BiologyHonours Info Session

4 Nov, 2019

Page 2: Department of Biology · 2019-11-05 · 1. Cryobiology of sturgeon germplasm 5. Effect of yolk and lipid quality on visual development, larval growth and survival--Zebrafish 2. Xenotransplantation

Important Notes on the Honours Programme:

• Honours is a privilege, not a right• Significant time commitment (summer and/or during semester)

Calendar Requirements:BSc requirements• 72 credits in Science, at least 30 at 3000 or 4000 level

Science Core• 6 credits MATH/COMP (note: MATH 1111 or 1151 is a prerequisite for BIOL

2701)• 3 credits physical science• 3 credits life science

Marks• min 3.0 CGPA in prescribed Honours work• min 3.0 CGPA in all coursework after first year• Thesis grade min “B”

Page 3: Department of Biology · 2019-11-05 · 1. Cryobiology of sturgeon germplasm 5. Effect of yolk and lipid quality on visual development, larval growth and survival--Zebrafish 2. Xenotransplantation

Biology Department Honours (75 credits)

• 60 credits as in the Major, including 3 credits from Biol 2701 or 4711

• 9 credits from BIOL 4990, 4903

• 6 additional credits from Biology at the 3/4000 level

To apply for admission to honours:

• Complete our departmental form found on the Biology website

• Once accepted by a supervisor, complete the declaration to pursue honours on the Regsitrar’s office website.

Page 4: Department of Biology · 2019-11-05 · 1. Cryobiology of sturgeon germplasm 5. Effect of yolk and lipid quality on visual development, larval growth and survival--Zebrafish 2. Xenotransplantation

Honours in Biology: FAQs

Q. What is it?A. Students work independently on an original research

question/problem in collaboration with a faculty member.

Q. Do I need to choose my own project?A. No, but you can certainly have input into your project. You need

to commit to a supervisor (and vice versa) and together you will come up with your project.

Q. Can I work on anything that interests me?A. Your project usually needs to fall within the realm of your supervisor’s research program.

Page 5: Department of Biology · 2019-11-05 · 1. Cryobiology of sturgeon germplasm 5. Effect of yolk and lipid quality on visual development, larval growth and survival--Zebrafish 2. Xenotransplantation

Q. What is the first step?A. Students should make an appointment to visit potential supervisors and ask about their research. Be prepared to tell faculty members about yourself.

Q. What are the important considerations in deciding on a project/supervisor?A. You should keep an open mind. Once you take ownership of a project, you may be surprised about how much interests you. You should think about:- how much direct supervision you would like/require.- the working relationship you will have with your supervisor.- your goals. Are you interested in potentially publishing your work? Attending conferences?- the type of research you like to do (e.g. field, lab, behaviour, ecology, physiology,

biochemistry, molecular biology, a combination)

Q. What is the Time commitment?A. You may have the opportunity to begin research in May and work throughout the summer. Alternatively, some projects can start in September. You should expect to spend approximately 10 hrs/week on thesis-related work.

Page 6: Department of Biology · 2019-11-05 · 1. Cryobiology of sturgeon germplasm 5. Effect of yolk and lipid quality on visual development, larval growth and survival--Zebrafish 2. Xenotransplantation

Q. How are supervisor-student decisions made?A. Once you have spoken to several potential advisors, you should let faculty

know if you would like to work with them. You should also let faculty know when you have made a commitment. Faculty talk to each other to try and place students appropriately. You must fill out a form by the final day of classes in December indicating your top three choices.

Q. What is BIOL 4903A. As an Honours student, you register in BIOL 4990 (Thesis = 6 credits) and

BIOL 4903 (3 credits). Both are year-long courses. BIOL 4903 (Current Advances) usually meets weekly for either class or a department seminar. You engage in thesis-related work (e.g. seminars, discussions).

Q. How am I graded?A. You receive a grade for 4903 from the 4903 instructor based on the work

you do in this course. Your 4990 grade comes from your written thesis (60% supervisor, 20% committee member) and a presentation you give on Honours Day in April (20%).

Page 7: Department of Biology · 2019-11-05 · 1. Cryobiology of sturgeon germplasm 5. Effect of yolk and lipid quality on visual development, larval growth and survival--Zebrafish 2. Xenotransplantation

The following faculty members are taking honoursstudents in 2020-21

ISRG – Independent Student Research GrantApplications due ~ 31 January 2020

Biology Faculty Associate Members

Dr. Campbell Dr. MacCormack (Chem/Biochem)

Dr. Crosby Dr. Popp (Geog & Env)

Dr. Hamilton Dr. Waller (Chem/Biochem)

Dr. Kaczmarska

Dr. Liefer

Dr. Litvak

Dr. Lloyd

Dr. Morash

Page 8: Department of Biology · 2019-11-05 · 1. Cryobiology of sturgeon germplasm 5. Effect of yolk and lipid quality on visual development, larval growth and survival--Zebrafish 2. Xenotransplantation

Brief summaries of faculty research interests:

Page 9: Department of Biology · 2019-11-05 · 1. Cryobiology of sturgeon germplasm 5. Effect of yolk and lipid quality on visual development, larval growth and survival--Zebrafish 2. Xenotransplantation

107 [email protected]

2-4 honours possibilities 2020/2021Many research visitors & exchanges

Students gain transferable skills in -Quantitative thinking-Data management & Analyses (R)-Project management-Writing

Students usually publish

Recent students have progressed to:-graduate school-MBA-Public Health-instrumentation companies-health professions-environmental policy...

Grit valued over Grades

[email protected]@[email protected]

Remote Sensing of Mudflat Productivity

Photoperiods in the Arctic OceanOceanic Low Oxygen ZonesCoastal Eutrophication([email protected])

Reactive Oxygen Stress

Page 11: Department of Biology · 2019-11-05 · 1. Cryobiology of sturgeon germplasm 5. Effect of yolk and lipid quality on visual development, larval growth and survival--Zebrafish 2. Xenotransplantation

Possible Research Questions

• How does stress affect synaptic function in the dorsomedial hypothalamus?

• Patch clamp electrophysiology using live rat brain slices

• How does the satiety hormone cholecystokinin suppress appetite?

• Recovery surgery in rats, injections of drugs into the brain

Page 12: Department of Biology · 2019-11-05 · 1. Cryobiology of sturgeon germplasm 5. Effect of yolk and lipid quality on visual development, larval growth and survival--Zebrafish 2. Xenotransplantation

Honours Students

• I plan to take on 2-3 Honours students

• Highly motivated, hard-working, collaborative

• Funding opportunities:

• New Brunswick Health Research Foundation Summer Studentship

• Independent Student Research Grant

Page 13: Department of Biology · 2019-11-05 · 1. Cryobiology of sturgeon germplasm 5. Effect of yolk and lipid quality on visual development, larval growth and survival--Zebrafish 2. Xenotransplantation

Research in the ACE (Aquatic Chemical Ecology) Lab

Cellular processes in microbes

Global BiogeochemistryAquatic Ecology

• The biochemistry and physiology of aquatic microbes

• The effect of microbial communities on aquatic consumers and global processes

• Microbial biotechnology to clean polluted waters and produce sustainable products

Page 14: Department of Biology · 2019-11-05 · 1. Cryobiology of sturgeon germplasm 5. Effect of yolk and lipid quality on visual development, larval growth and survival--Zebrafish 2. Xenotransplantation

DNA

RNA

Phospholipids

Polyphosphate

Diatom cell

Surface P

Nucleus

Honours opportunities in the ACE Lab

Project 1: Phosphorus dynamics in marine phytoplankton• Using new methods to study polyphosphate, a globally

important and poorly understood molecule• Exploring how a variety of phytoplankton species use

phosphorus, the ocean’s ultimate limiting nutrient• New biotechnology for wastewater remediation

Project 2: Community ecology of mudflat microbial food sources (w/ Dr. Hamilton &Dr. Campbell)• Using chemotaxonomy to examine intertidal mudflat

biofilms that support migratory birds• Field sampling and manipulative experiments in Fundy

mud!

Page 15: Department of Biology · 2019-11-05 · 1. Cryobiology of sturgeon germplasm 5. Effect of yolk and lipid quality on visual development, larval growth and survival--Zebrafish 2. Xenotransplantation

Project 3: Origins of harmful algal blooms in New Brunswick lakes (w/ Dr. Kurek)• Paleoecology of NB lakes to understand why toxic

blooms are increasing• Field work in remote NB lakes to sample

phytoplankton, zooplankton, and water quality and to develop new monitoring tools

Project 4: Ecosystem impacts of glyphosate herbicides (w/ Dr. Jesse Popp)• Exploring impacts of glyphosate spraying after logging

on terrestrial and aquatic communities• Collaborating with indigenous communities in Ontario

and applying traditional knowledge to field studies• Rugged fieldwork in Ontario forests

Honours opportunities in the ACE Lab

Page 16: Department of Biology · 2019-11-05 · 1. Cryobiology of sturgeon germplasm 5. Effect of yolk and lipid quality on visual development, larval growth and survival--Zebrafish 2. Xenotransplantation

1. Cryobiology of sturgeon germplasm

5. Effect of yolk and lipid quality on visual development, larval growth and survival--Zebrafish

2. Xenotransplantation. 3. Development of sperm and eggs in

surrogates.4. Opens up ability to do more work on

sperm/egg interactions, sperm-to-egg ratios, tests of sperm quality and modeling

7. Spatial ecology of juvenile and Atlantic sturgeon

6. Stable isotopes—ecology and as a forensic tool to catch poachers and stop illegal trade in caviar

8. Sexual dimorphism in sturgeons

Litvak Lab

Page 17: Department of Biology · 2019-11-05 · 1. Cryobiology of sturgeon germplasm 5. Effect of yolk and lipid quality on visual development, larval growth and survival--Zebrafish 2. Xenotransplantation

Comparative Physiology

Evolution of hypoxia/thermal tolerance

Mitochondrial physiology

Cardiac vs. skeletal muscle physiology

Dr. Andrea [email protected]

Page 18: Department of Biology · 2019-11-05 · 1. Cryobiology of sturgeon germplasm 5. Effect of yolk and lipid quality on visual development, larval growth and survival--Zebrafish 2. Xenotransplantation
Page 19: Department of Biology · 2019-11-05 · 1. Cryobiology of sturgeon germplasm 5. Effect of yolk and lipid quality on visual development, larval growth and survival--Zebrafish 2. Xenotransplantation

Shorebird and coastal ecology

Dr. Diana Hamilton

([email protected])

Page 20: Department of Biology · 2019-11-05 · 1. Cryobiology of sturgeon germplasm 5. Effect of yolk and lipid quality on visual development, larval growth and survival--Zebrafish 2. Xenotransplantation

Possible projects• Shorebird movement, duration of stay and habitat use in

coastal NB • Capture, tag, radiotrack a variety of species, behaviour and diet work

• Primary productivity on mudflats• Quantify primary production and standing crop of diatoms, examine

aspects of ecology of biofilms (in conjunction with Drs. Campbell and Liefer)

• Intertidal community ecology• Examine top down and bottom up factors, including primary

production, influencing intertidal systems.

Page 21: Department of Biology · 2019-11-05 · 1. Cryobiology of sturgeon germplasm 5. Effect of yolk and lipid quality on visual development, larval growth and survival--Zebrafish 2. Xenotransplantation

Helpful traits in honours students in my lab

• Interest in field ecology, lab analytical techniques, quantitative analyses, and publishing results.

• Comfort with strange hours, hard work, unpredictability.

• Happy working in groups.

• Good birding skills or interest in learning, fondness for mud and things that live in it.

If interested in working in my lab, please contact me. I will put you in touch with

current and former lab members.

Page 22: Department of Biology · 2019-11-05 · 1. Cryobiology of sturgeon germplasm 5. Effect of yolk and lipid quality on visual development, larval growth and survival--Zebrafish 2. Xenotransplantation

Vett LloydTick-vectored diseases/Lyme diseaseZoonosesMolecular genetics

T101

O+F

+

T112

O+F

+

100bp

ladder

Page 23: Department of Biology · 2019-11-05 · 1. Cryobiology of sturgeon germplasm 5. Effect of yolk and lipid quality on visual development, larval growth and survival--Zebrafish 2. Xenotransplantation

Potential honours projects:

- 2 honours positions- Summer funding likely available but either May or Sept.

start is acceptable- Projects all involve and molecular genetics (PCR and

friends). Some interaction with Lyme patients and/or the public may be required for some projects

- Independent studies students are also welcome

Page 24: Department of Biology · 2019-11-05 · 1. Cryobiology of sturgeon germplasm 5. Effect of yolk and lipid quality on visual development, larval growth and survival--Zebrafish 2. Xenotransplantation

What pathogens are in our ticks? Molecular testing of tick bank specimens to find pathogens

Molecular ecology – molecular diet analysis of coyote, fox scat and cat (who’s lunch project)

Profiling of oncogenes in human and canine tissuesColorectal cancer – molecular histology (requires

summer internship in the Upper River Valley Hospital in Woodstock. Suitable for someone serious about a medical career).

Molecular histology and sequence analysis of human tissue

Projects

Page 25: Department of Biology · 2019-11-05 · 1. Cryobiology of sturgeon germplasm 5. Effect of yolk and lipid quality on visual development, larval growth and survival--Zebrafish 2. Xenotransplantation

MacCormack Lab – Barclay [email protected], maccormacklab.com

• Fish (mostly) physiology and metabolism

• Natural environmental stressors: oxygen, temperature, pH

• Anthropogenic stressors: contaminants (nanoparticles)

• Whole animals, isolated organs, isolated cells, and protein level studies

Page 26: Department of Biology · 2019-11-05 · 1. Cryobiology of sturgeon germplasm 5. Effect of yolk and lipid quality on visual development, larval growth and survival--Zebrafish 2. Xenotransplantation

• Fall 2020 projects: • Role of taurine in supporting cardiac function• Accelerated growth in salmon reared under hyperoxia (with Morash)• Cardiotoxicity of nanoparticles

• Students Publish!• Williams KJ, Cassidy AA, Verhille CE, Lamarre SG, MacCormack TJ. 2019. Diel cycling hypoxia enhances

hypoxia-tolerance in rainbow trout (Oncorhynchus mykiss): Evidence of physiological and metabolic plasticity. J Exp Biol 222: jeb 206045.

• Campbell LA, Gormley PT, Bennett JC, Murimboh JD, MacCormack TJ. 2019. Functionalized silver nanoparticles depress aerobic metabolism in the absence of overt toxicity in brackish water killifish, Fundulus heteroclitus. Aquat Toxicol 213: 105221.

• Callaghan NI, Williams KJ, Bennett JC, MacCormack TJ. 2018. Nanoparticulate-specific effects of silver on teleost cardiac contractility. Environ Pollut 237: 721-730.

• Henry EF, MacCormack TJ. 2018. Taurine protects cardiac contractility in Fundulus heteroclitus by enhancing sarcoplasmic reticular Ca2+ cycling. J Comp Physiol B 188, 89-99.

MacCormack Lab – Barclay [email protected], maccormacklab.com