Please note I wish this native well... I want to inform you that I choose not to do chart analysis as of late.I do offer the readers of HDF insights and knowledge on jyotish subject matter and enjoy posting what little I know.That said, just a few ideas [ I have not constructed this persons chart] : Yet one must consider the differences of the lagnamsa ( that of the body) and that of karakamsa ( soul or atman); Since this is a body condition one must look to the lagna, its lord, its location ( paka lagna) and the influences thereof. Rahu dasa ( if you are talking Vimshottari dasa) is challenging for some; If well placed in the 3rd house one can consider a happy and long life, yet will have some grief due to brothers as it will be in the 3rd house, and also aspect the 9th from the 3rd ( the 11th) and additional brothers; Even if it was the Atma karaka, the atma karaka dasa period increases the notion of purification of the native. Saturn as you know will bring grief unless placed in upahayasthanas of the 3rd, 6th, 10th and 11th ( as the the benefits grow over time). Yet note that diabetes is an affliction of Jupiter not of rahu. So an ill-placed jupiter with malefic aspects can make this occur. It also can cause an over-weight condition and an out-of-control sweet tooth. I take note of one thing that you said, The issues for this native started at 32. At age 32 the naisargika [natural] dasa of Jupiter begins and runs to 50 years of age. This dasa system is ruled by Brahma and can apply to all humans. Interesting to me that both these conditions have occurred - Jupiter dasa and the dis-ease that jupiter offers - diabetes.Hope all turns out well for this person...naisargika [natural] dasa division1______ Moon - ones birth to 1 year old2 ______Mars -1 to 3 years old3 ______Mercury - 3 to 12 years old4 ______Venus - 12 to 32 years old5 ______Jupiter - 32 to 50 years old6 ______Sun - 50 years to 70 years old7 ______Saturn- 70 to 120 years oldpra Jupiter is the karaka of the 5th house. 5th house is higher learning , children ( and subordinates), disciples and followers, spiritual techniques ( higher learning),. Jupiter as guru is most fitting. The quality of dharma in ones actions, giving without expectations; Jupiter's qualities as guru and as akasa is nourished here with giving and that of patience and forgiveness - some call this grace, one benefits from the qualities of this karaka-s influence on the 5th house affairs. Mars and Saturn are the karaka-s of the 6th house. The 6th house some call it a house of difficulties e.g. worries, anxieties, obstacles, enemies (external and internal i.e. vices), thieves, challenges, tests, urge for perfection (self-improvement techniques, competitive power , difference and conflicts. To win the favor of the karaka-s here is one of strength. Such a strength that one's enemies do not even consider retaliation or challenges to the native. My teacher used to call this invincibility. What does this strength depend on? High character, dharma, and right action ( purposeful in one's duty). For Saturn's influence it will always be diligence and purposeful work.Lets stop here More discussion on karaka-s are shown in the posts above.We can address the remaining 6 in the next post. Venus is the karaka of the 7th house Saturn is the karaka of the 8th house The Sun and Jupiter are the karaka-s of the 9th house Sun, Jupiter, Mercury and Saturn are the karaka-s of the 10 house Jupiter and Saturn are the is the karaka-s of the 11th house/ Ketu and Saturn are the karaka-s of the 12th house.