curriculum vitae - shp › cv › paddon-jones_d-cv.pdf · curriculum vitae name: douglas...

CURRICULUM VITAE

NAME: Douglas Paddon-Jones, Ph.D., FACSM August, 2017 PRESENT POSITION: Sheridan Lorenz Distinguished Professor in Aging and Health Department of Nutrition and Metabolism

School of Health Professions The University of Texas Medical Branch

� 301 University Blvd

Galveston, Texas. 77555-1124 USA Email: [email protected]

Office: 409-772-3073 || Admin: 409-772-2578 || Lab: 409-747-9149 EDUCATION:

2000-2001 Post-Doctoral Fellowship Protein Metabolism, Department of Surgery The University of Texas Medical Branch Shriners Hospital for Children. Galveston, Texas. USA

1997-1999 Doctor of Philosophy (Ph.D.) Human Movement Studies The University of Queensland. Australia

1995-1996 Master of Science (MS) Exercise Physiology Ball State University, Muncie, Indiana. USA

1994 Bachelor of Science with 1st class Honours (BSc Hons, 1st Class)

Human Movement Studies The University of Queensland. Australia

1990-1993 Bachelor of Science (BSc) The University of Queensland. Australia

1987-1989 Diploma of Applied Science (Dip.App.Sc)

Diagnostic Medical Imaging Queensland University of Technology. Australia

ADDITIONAL COURSES AND TRAINING:

2008 University of Texas, TeleCampus (UTTC) Seminar Series, Austin, Tx 2007 Scholar in Education

Douglas Paddon-Jones _____________________________________________________________________ 2

Office of Educational Development, UTMB

2006 Facilitation Skills Workshop Integrated Medical Curriculum, Office of Educational Development 2002 Fellowship in Contrast Enhanced Ultrasound and Skeletal Muscle

Microvascular Perfusion University of Virginia, Charlottesville

2000 Tracer Methodology in Biology and Medicine Department of Surgery / Metabolism Unit, UTMB

1996 Certified Strength and Conditioning Specialist (CSCS) National Strength and Conditioning Association. USA

1993 Post-Graduate Elective in Sports Medicine

Australian Sports Medicine Federation, Brisbane, Australia


PROFESSIONAL EXPERIENCE:

The University of Texas Medical Branch:

2016- Sheridan Lorenz Distinguished Professor in Aging and Health 2013 - Director, Translational Research in Physical Activity & Functional

Recovery Laboratory 2013- Co-Leader, Clinical Research Resource Core (CR-RC1). Claude D.

Pepper Older Americans Independence Center 2012- Professor (with tenure). Department of Nutrition and Metabolism

2007-2011 Vice-Chair, Institutional Review Board 2006-2011 Associate Professor, Physical Therapy

2006-2010 Director of Exercise Studies. General Clinical Research Center.

2006- Member, Graduate Faculty. Preventative Medicine and Community Health Graduate Program. Graduate School of Biomedical Sciences

2006- Curriculum Faculty Member, Division of Rehabilitation Sciences 2005-2006 Director, Exercise Metabolism Lab. Shriners Hospital for Children 2003-2006 Assistant Professor. Department of Surgery 2001-2002 Research Scientist. Surgery and Shriners Hospital for Children

Other Professional Experience: 2014-2015 Visiting Scholar, Ingestive Behavior Research Center Purdue Univ. 2013 - Adjunct Professor, University of the Sunshine Coast, Australia 1994-1995 Strength and Conditioning Coach. Brisbane Bullets, Australian

National Basketball League

1989-1995 Staff / Locum Radiographer. Private Practice. Queensland, Australia


COMMITTEE RESPONSIBILITIES:

The University of Texas Medical Branch: 2015 Institutional Security and Privacy Compliance Committee

2015- Student Grievance and Appeals Committee, SHP

2014- Institutional Faculty Grievance Board

2014- Institute for Translational Sciences, Scientific Review Committee

2013 Search Committee, UTMB Vice President and CRO

2012- Chair, Post Tenure Review Committee, SHP

2012- Chair, Institutional Committee on Scientific Integrity

2012- Academic Enterprise Space Advisory Committee

2012- Postdoctoral Advisory Committee

2008-2009 Research Committee, Orthopedics Residency Program

2007-2011 Executive Committee, Institutional Review Board

2007-2009 Chair, Committee on Scientific Integrity

2007 Scholarship and Awards Committee, Physical Therapy

2005-2011 Member, Institutional Review Board.

Other committee / advisory board responsibilities:

2015- Leprino Foods, Nutrition Advisory Board

2015 Kraft Foods External Advisory Panel on Protein Nutrition

2013 Steering Committee. Protein Summit 2.0. Washington DC

2011 Sarcopenia Advisory Board. Takeda Global R&D

2011 Planning Committee, Institute of Medicine (IOM) Workshop on

Nutrition and Healthy Aging in the Community

2009-2012 NSBRI/NASA Space Human Factors & Habitability, Musculoskeletal

Alterations Discipline Co-Lead

2009- Scientific Advisory Panel, American Egg Board

2008- Whey Protein Advisory Panel. National Dairy Council

2008- Mentor, Graduate Training Program in Space Life Sciences

National Space Biomedical Research Institute and NASA.

2007 Steering Committee. Protein Summit. Charleston, South Carolina


TEACHING EXPERIENCE: The University of Texas Medical Branch:

2013- Guest lecturer, PHYT 6342 Functional Training Techniques in

Physical Therapy 2009-2011 Course Coordinator: PHTY: 6117. Imaging of the Musculoskeletal

and Neuromuscular Systems. Physical Therapy 2007- Lecturer. PMCH 6355: Tracer Methodology 2006-2008 Lecturer. NASA BBSC 6102: Space physiology. Grad School of

Biomedical Sciences Preventative Medicine and Community Health

2006 Facilitator. Cardiovascular and Pulmonary Physiology Course School of Medicine

2005-2006 Course coordinator. Developing a Clinical Research Protocol 3rd Year Surgery Rotation. School of Medicine 2004-2005 Course coordinator. Metabolism Workshops. 3rd Year Clinical

Rotation. School of Medicine

2004-2006 Facilitator. Essentials of Endocrinology and Reproduction. School of Medicine

2001-2004 Student Supervisor. High School Summer Research Program

National Space Biomedical Research Institute: NSBRI / NASA 2002 Student Supervisor. National Youth Leadership Forum on Medicine

Graduate School of Biomedical Sciences

The University of Queensland: 1998-1999 Coordinator HM102 - Physical Fitness for Sport and Health 1998 Tutor HM331 – Exercise Management Practicum 1997 Coordinator HM431 – Major Practicum (Exercise Management) 1997-1998 Tutor HM345 – Sports Medicine 1997-1998 Tutor HM274 – Exercise Physiology 1998-1999 Tutor HM373 – Advanced Exercise Physiology


SUPERVISION AND MENTORING:

2016 Marlou Dirks External Ph.D Committee Member Maastricht University, The Netherlands

2016 Caoileann Murphy External Ph.D Committee Member McMaster University, Canada

2015- Elfego Galvan, Ph.D., RD.

Supervisor, Postdoc Fellow 2015- Lauren O’Conner

Ph.D. Dissertation Committee Member Purdue University

2015 Jessica Spahn, MS, RCEP, CPT Supervisor, Research Coordinator 2013-2016 Sneha Nagamma, M.D. Supervisor, Senior Laboratory Manager 2012-2015 Emily Arentson-Lantz, Ph.D.

Supervisor, Postdoc Fellow (Current: Research Scientist, UTMB)

20012- 2015 Paul Reidy

Ph.D. Dissertation Committee Member (Current: Postdoc. University of Utah) - Kempner postdoctoral scholar 2015-2017

2010-2012 Joni Mettler, Ph.D. Supervisor, Postdoc Fellow

(Current: Assistant Professor, Texas State University) 2009-2012 Madonna Mamerow, Ph.D. Supervisor, Postdoc Fellow 2009-2013 David Gunderman

Ph.D. Dissertation Committee Member (Current: Postdoc. University of Florida)

2008-2013 Barbara Doucet, OTR, Ph.D.

Mentor, RRCD Scholar, Division of Rehabilitation Sciences (Current: Assistant Professor, LSU)


2007- 2013 Kirk English Ph.D. Mentor (Current: Senior Scientist, NASA-Johnson Space Center) - Charles F. Otis Endowed Award for Clinical Research 2011 - Donald Micks Scholarship Recipient 2010 - Emily Dupree Scholarship Recipient 2010 - Texas Space Grant Consortium Fellow 2010-11

2007-2012 Shanon Casperson Ph.D. Co-Mentor and Dissertation Committee Member (Current: Postdoc Fellow USDA-ARS, North Dakota) - Peyton and Lydia Schapper Endowed Scholarship 2010 - Energy and Macronutrient Metabolism Research Interest

Section of the American Society for Nutrition Award 2010 - Energy and Macronutrient Metabolism Research Interest

Section of the American Society for Nutrition Award 2009 - Isotec Student Sponsorship at Experimental Biology 2009 - Peyton and Lydia Schapper Endowed Scholarship 2007 - The American Physiological Assoc., Environmental &

Exercise Physiology, Predoctoral Gatorade Award 2007 - Isotec Student Sponsorship at Experimental Biology 2007

2007- 2011 Christopher Fry

Ph.D. Dissertation Committee Member (Current: Assistant Professor, UTMB) - Kempner postdoctoral scholar 2011-2013

2007-2010 William Amonette Ph.D. Dissertation Committee Member

(Current: Assistant Professor, University of Houston) 2007-2010 Erin Glynn

Ph.D. Dissertation Committee Member (Current: Senior Scientist, Beach Body LLC)

2004-2006 T. Brock Symons, Ph.D.

Supervisor, Postdoc Fellow (Current: Assistant Professor, University Louisville)

2004-2006 Melanie Green-Cree, M.D., Ph.D.

Ph.D. Preventative Medicine and Community Health (Current: Instructor, University of Colorado)


RESEARCH ACTIVITIES: Clinical Translational Research: My research program focuses on the regulation of muscle metabolism, mass and function in healthy and at-risk populations. Thematic areas include:

i) the effects of physical inactivity (bed rest) on young, middle-aged and older adults ii) the effects of amino acid / protein consumption on acute markers of anabolism

Recent highlights from our team include:

• demonstrating that physical inactivity greatly accelerates the loss of muscle mass and function in middle aged and older adults

• showing that nutritional (amino acid/leucine/whey) support may partially protect muscle health during periods of inactivity

• proposing the "Catabolic Crisis Model" of muscle/function loss as an opportunity to provide targeted prevention and treatment interventions

• conceiving and providing proof of concept for the "Even Protein Distribution" theory GRANT SUPPORT:

Ongoing

RO1 NR012973-01 Paddon-Jones (PI) 10/11-10/17 NIH/NINR Preserving muscle mass and function in bedridden older adults The goal of this study is to reduce the negative consequences of physical inactivity and promote rehabilitation in aging muscle. (Total costs: $2.7M) Dairy Research Institute Paddon-Jones (PI) 09/12-12/16 National Dairy Council Whey protein, aging and physical inactivity The goal of this study is to determine if whey protein supplementation can preserve muscle mass and function during inactivity. (Total costs: $565K) Dairy Research Institute Paddon-Jones (PI) 06/13-07/16 Dairy Council of California Distributed protein intake, whey protein and aging. The goal is to optimize protein distribution and reduce muscle and function loss during bed rest. (Total costs: $178K)


Ongoing collaborative U01AR071150 Rasmussen (PI) 12/16-12/21 NIH Molecular Transducers of Physical Activity in Humans, Adult Clinical Center. The goal is to assemble a comprehensive map of the molecular changes that occur in response to movement and relate these changes to the benefits of physical activity. Role: Clinical research core leader

R56 AG051267 Rasmussen (PI) 09/15-08/16 NIH/NIAMS Nutrient Sensing and Signaling in Aging Muscle The goal is to determine the role of muscle mTORC1 signaling in the etiology of anabolic resistance in older adults and whether physical activity interventions can be used as a treatment to reverse sarcopenia and improve the anabolic response to daily nutrition. Role: Co-Investigator P30 AG024832 Volpi (PI) 06/10-04/20 NIH/NIA UTMB Claude Pepper Older Americans Independence Center The goals of this center grant is to support basic and clinical research on ways for elderly Americans to lead a more independent life for as long as possible. The center is focused on translating basic findings of muscle biology in aging to improve functional outcomes and recovery from illness in older adults. Role: Co-Investigator, Co-leader: Clinical Research Resource Core Industry Campbell (PI) 10/13-09/16

National Pork Board, American Egg Board-Egg Nutrition Center, Dairy Research Institute, and National Cattlemen's Beef Association

Effects of dietary protein patterning on weight loss and resistance training-induced changes in body composition, skeletal muscle, and indices of metabolic syndrome. The goal is to evaluate the effects of patterning of dietary protein intake on energy-restriction induced changes. Site: Purdue University Role: Co-I

Industry Campbell (PI) 05/2015 – 02/2017

National Cattlemen’s Beef Association and National Pork Board. Effects of incorporating red meat into a Mediterranean-style dietary pattern on cardiometabolic

and emotional well-being. This research project will assess the impact of including greater amounts of red meat in a Mediterranean-style dietary pattern on changes in metabolic and emotional well-being. Site: Purdue University Role: Co-I


Completed R21 AR062479 Lang (PI) 07/12-08/14 NIH/NINR PET/CT of Skeletal Muscle Amino Acid Kinetics Site: University of California San Francisco Role: Co-I

NNJ08ZSA002N Paddon-Jones (PI) NSBRI 06/09-06/13 An integrated low-volume nutritional countermeasure to maintain muscle mass and function during space exploration.

Abbott Education Paddon-Jones (PI) 09/12 -10/13 Seminar Series in Rehabilitation and Nutrition. High Point Pharmaceuticals Paddon-Jones (PI) 09/12-06/13 A randomized, double-blind, placebo controlled, phase I study to evaluate the safety and tolerability of 28 day treatment with HPP593 capsules in healthy volunteers during and after limb immobilization. NCBA Paddon-Jones (PI) 06/09 – 07/11 National Cattlemen’s Beef Association Protein Needs for Optimal Meal Response RO1 Sheffield-Moore (PI) 05/08-05/012 NIH/NIA Nutrition and anabolic interventions in cancer cachexia Role: Co-I UTMB Volpi (PI) 01/09-01/11 Institute Translational Science Multidisciplinary Translational Team Grant: Muscle Aging and Sarcopenia. Role: Co-I/Project coordinator RO1 AG021539-03 Sheffield-Moore (PI) 09/03/05/09 NIH/NIA Muscle Perfusion and Protein Metabolism in Elderly and Young Role: Co-I UT TeleCampus Utsey (PI) 08/08 -08/09 Pharmacology and Imaging: Online courses for DPT students and practicing physical therapist Role: Co-I/Course Instructor UTMB Paddon-Jones (PI) 04/07-04/08 Claude D. Pepper Older Americans Independence Center Restoration of Cell Signaling and Muscle Protein Synthesis in the Elderly


UTMB Paddon-Jones (PI) 12/07-08/08 Center for Rehabilitation Sciences Infrastructure grant to support submitted PO1 “Translational Research in Muscle Metabolism” Industry Paddon-Jones (PI) 06/05 – 09/07 National Cattlemen’s Beef Association Effect of dose and composition of dietary beef on muscle protein anabolism in young and elderly NNJ04HD68G. Ferrando/ Paddon-Jones (PI) 08/04-05/07 NASA Artificial gravity as a multi-system countermeasure to bedrest deconditioning NPFR 00403 Paloski (PI) 07/05-06/08 NASA 90 Day Bedrest Campaign 3C. Role: Project lead, muscle team NCBA Paddon-Jones (PI) 03/05 – 09/05 National Cattlemen’s Beef Association Beef ingestion and muscle protein metabolism GCRC Pilot Program Grant Paddon-Jones (PI) 06/02 – 06/03 Regulation of muscle protein synthesis in the young and elderly Role: PI AG 023591 Evans (PI) 07/05-06/06 NIH/NIA Program Project Bedrest and Aging: Amino Acid Supplementation and Muscle (UTMB/UAMS) Role: Co-I

R01 AG 15780-02 Wolfe (PI) 09/03 – 5/08 NIH Muscle Protein Metabolism and Nutrition in the Elderly Role: Co-I NPFR00205 Wolfe (PI) 05/01-01/04 National Space Biological Research Institute Skeletal muscle response to bedrest and cortisol induced stress Role: Co-I

MEMBERSHIP IN SCIENTIFIC SOCIETIES:

Sports Medicine Australia American Physiological Society American College of Sports Medicine American Society for Nutrition


HONORS AND AWARDS:

2016 Sheridan Lorenz Distinguished Professor in Aging and Health The University of Texas Medical Branch

2015 Fellow. American College of Sports Medicine

2012 The Max K. Horwill Distinguished Nutrition Lectureship

Saint Louis University

2012 Senior Fellow, Sealy Center on Aging The University of Texas Medical Branch

2009 SHP Award for Research Excellence

The University of Texas Medical Branch

2006 Vernon Young International Award for Amino Acid Research American Society for Nutrition

2002 Fellow, Sealy Center on Aging The University of Texas Medical Branch

1999 Warren Walsh Memorial Award Outstanding Ph.D. Graduate. The University of Queensland

1998 Gatorade Sports Science Institute Student Research Award Doctoral Thesis. The University of Queensland 1997-99 Post-Graduate Research Scholarship

The University of Queensland 1995-96 Post-Graduate Scholarship

Ball State University, IN. USA NIH STUDY SECTION REVIEWS:

2015 National Center for Complementary & Integrative Health [NCCIH)] Study Section, November 4

National Institute of Diabetes and Digestive and Kidney Diseases [NIDDK]

Special Emphasis Panel, July 9 Special Emphasis Panel. March 18

2014 NIH-Nursing and Related Clinical Sciences [NRCS] Study Section October 9-10 2014 NIH - Musculoskeletal Rehabilitation Sciences [MRS]

Study Section June 26-27


A. ARTICLES IN PEER-REVIEWED JOURNALS: H-index : 34

1. Arentson-Lantz EJ, Saeed IH, Frassetto LA, Masharani U, Harnish RJ, Seo Y, VanBrocklin HF,

Hawkins RA, Mari-Aparici C, Pampaloni MH, Slater J, Paddon-Jones D, Lang TF. 11C-L-methyl methionine dynamic PET/CT of skeletal muscle: response to protein supplementation compared to L-[ring 13C6] phenylalanine infusion with serial muscle biopsy. Ann Nucl Med. Mar 4 -1157-4. 2017

2. Ellison, J.B., Drummond, M. Dickinson, J.M., McGaugh, J.M., Paddon-Jones, D., Volpi, E. Short-Term Intensive Rehabilitation Induces Recovery of Physical Function After 7 Days of Bed Rest in Older Adults. J. of Acute Care Physical Ther. 7(4): 156-163. 2016

3. Lamon, S. Zacharewicz, E. Arentson-Lantz, E., Della Gatta, P.A., Ghobrial, L., Gerlinger-Romero, F., Garnham, A., Paddon-Jones, D., Russell, A.P. Erythropoietin does not enhance skeletal muscle protein synthesis following exercise in young and older adults. Frontiers in Physiology. 8;7:292. 2016

4. English, K.L., Mettler, J.A., Ellison JB., Mamerow, M.M., Arentson-Lantz, E., Pattarini JM., Ploutz-Snyder R., Sheffield-Moore, M., Paddon-Jones, D. Leucine partially protects muscle mass and function during bed rest in middle-aged adults. Am. J. Clin. Nutr. 103(2):465-73. 2016

5. Arentson-Lantz E., English KL, Paddon-Jones D., Fry CS. Atrophy of skeletal muscle fibers and decline in satellite cell content in middle-aged adults during bed rest. J Appl. Physiol. 120(8):965-75. 2016

6. Markofski MM, Dickinson JM, Drummond MJ, Fry CS, Fujita S, Gundermann DM, Glynn EL,

Jennings K, Paddon-Jones D, Reidy PT, Sheffield-Moore M, Timmerman KL, Rasmussen BB, Volpi E. Effect of age on basal muscle protein synthesis and mTORC1 signaling in a large cohort of young and older men and women. Exp Gerontol. 65:1-7. 2015

7. Mamerow, M.M., Mettler, J.A., English, K.L., Casperson, S.L., Arentson-Lantz, E., Sheffield-

Moore, M., Layman, D.K., Paddon-Jones, D. Dietary Protein Distribution Positively Influences 24-h Muscle Protein Synthesis in Healthy Adults. J. Nutr. 10.3945/jn.113.185280. 2014

8. Casperson SL, Sheffield-Moore M, Hewlings SJ, Paddon-Jones D. Leucine supplementation

chronically improves muscle protein synthesis in older adults consuming the RDA for protein. Clin. Nutr. 31(4):512-9. 2012

9. Drummond MJ, Dickinson JM, Fry CS, Walker DK, Gundermann DM, Reidy PT, Timmerman KL, Markofski MM, Paddon-Jones D, Rasmussen BB, Volpi E. Bed rest impairs skeletal muscle amino acid transporter expression, mTORC1 signaling, and protein synthesis in response to essential amino acids in older adults. Am J Physiol Endocrinol Metab.15; 302(9):E1113-22. 2012


10. Sheffield-Moore, M., Dillon, E.L., Casperson, S.L., Gilkison, C.R., Paddon-Jones, D., Durham, W.J., Grady, J.J., Urban, R.J. A Randomized Pilot Study of Monthly Cycled Testosterone Replacement or Continuous Testosterone Replacement Versus Placebo in Older Men. J Clin Endocrinol Metab. 96(11):E1831-7. 2011

11. Symons T.B., Sheffield-Moore, M., Mamerow, M., Wolfe,R.R. and Paddon-Jones, D. The

Anabolic Response to Resistance Exercise and a Protein-Rich Meal is not Diminished by Age. J. Nutr. Health and Aging. 15(5):376-81. 2011

12. Durham WJ, Casperson SL, Dillon EL, Keske MA, Paddon-Jones D, Sanford AP, Hickner RC, Grady JJ, Sheffield-Moore M. Age-related anabolic resistance after endurance-type exercise in healthy humans. FASEB J. 24(10):4117-27. 2011

13. Cree, M.G., Paddon-Jones, D., Newcomer, B.R., Ronsen, O, Aarsland, A., Wolfe, R.R., Ferrando A. Twenty-eight-day bed rest with hypercortisolemia induces peripheral insulin resistance and increases intramuscular triglycerides. Metabolism. 59 (5):703-10. 2009

14. Ferrando*, A.A., Paddon-Jones*, D. Hays, N.P., Kortebien, P., Ronsen, O., Williams, R.H.,

McComb, A., Symons, T.B., Wolfe, R.R., Evans, W. EAA supplementation to increase nitrogen intake improves muscle function during bed rest in the elderly. (*contributed equally)Clin. Nutr. 29(1):18-23. 2010

15. Symons T.B., Sheffield-Moore M., Chinkes D.L, Ferrando A.A., and Paddon-Jones D. NASA Artificial gravity maintains skeletal muscle protein synthesis during 21 days simulated microgravity. J.Appl. Physiol. 107(1):34-8. 2009

16. Symons T.B., Sheffield-Moore, M., Wolfe,R.R. and Paddon-Jones, D. A moderate serving of

high-quality protein maximally stimulates skeletal muscle protein synthesis in young and elderly. J. Am. Dietetic Assoc. 109(9):1582-6. 2009

17. Dillon E.L., Sheffield-Moore, M., Paddon-Jones, D., Gilkison, C., Sanford, A.P., Casperson,

S.L., Jiang, J., Chinkes, D.L. and Urban, R.J. Amino acid supplementation increases lean body mass, basal muscle protein synthesis and IGF-I expression in older women. J. Clin. Endocrinol. Metab., 94(5):1630-7 2009

18. Kortebein P., Symons, T.B., Ferrando, A.A., Paddon-Jones, D., Ronsen, O., Protas, E., Conger,

S., Lombeida, J., Wolfe, R.R., Evans, W.J. Functional impact of ten days bed rest in healthy older adults. J. Geron. 63(10):1076-81. 2008

19. Katsanos CS, Chinkes DL, Paddon-Jones D, Zhang XJ, Aarsland A, Wolfe RR. Whey protein

ingestion in elderly persons results in greater muscle protein accrual than ingestion of its constituent essential amino acid content. Nutr Res. 28(10):651-8. 2008

20. Cree M.G., Newcomer B.R., Read, L.K., Sheffield-Moore M., Paddon-Jones D., Chinkes,

D., Aarsland, A., Wolfe, R.R. Plasma triglycerides are not related to tissue lipids and insulin sensitivity in elderly following PPAR-alpha agonist treatment. Mech Ageing Dev. 128(10):558-65. 2007


21. Dillon E.L., Volpi E., Wolfe R.R., Sinha S., Sanford A.P., Concepcion A.D., Urban R.J., Casperson S.L., Paddon-Jones D., Sheffield-Moore M. Amino acid metabolism and inflammatory burden in ovarian cancer patients undergoing intense oncological therapy. Clin. Nutr. 26(6):736-43. 2007

22. Symons, T.B., Cocke, T.L., Schutzler, S.E., Wolfe, R.R. and Paddon-Jones, D.

Aging does not impair the anabolic response to a protein-rich meal. Am. J. Clin. Nutr. 86; 451-6. 2007

23. Fitts, R.H., Romatowski, J., Peters, J., Lim,W., Ferrando, A.A., Paddon-Jones, D., Wolfe, R.R.

Effect of essential amino acid supplements on the functional capacity of fast- and slow-twitch muscle fibers in response to bed rest. Am. J. Physiol. Cell. 293(1):C313-20. 2007.

24. Uchakin, P.N., Stowe, R.P., Paddon-Jones, D., Ferrando, A.A., Tobin, B.W., Wolfe, R.R. Effects of bed-rest on type 1 vs. type 2 cytokine secretion and latent herpes virus reactivation. Aviat Space Environ Med. 78(6):608-12. 2007.

25. Paddon-Jones, D., Sheffield-Moore, M., Cree,M.G., Hewlings, S.J., Aarsland, A.A., Wolfe,

R.R., Ferrando, A.A. Increased muscle protein catabolism during inactivity and stress. J. Clin. Endocrinol Metab. 91(12):4836-41. 2006

26. Sheffield-Moore, M., Paddon-Jones, D., Casperson, , S.L., Gilkison, C., Volpi, E., Wolf, S.E.,

Jiang, J., Rosenblatt, J., Urban, R.J. Androgen Therapy Induces Muscle Protein Anabolism in Older Women. J. Clin. Endocrinol Metab. Oct;91(10):3844-9. 2006

27. Zwart, S.R, Davis-Street, J.E., Paddon-Jones, D., Ferrando, A.A., Wolfe, R.R., Smith, S.M.

Amino acid supplementation increases bone resorption during simulated weightlessness. J. Appl. Physiol. 99: 134-140, 2005

28. Paddon-Jones, D., Sheffield-Moore, M., Zhang X.J, Katsanos, C.S., and Wolfe, R.R.

Differential stimulation of muscle protein synthesis in elderly humans following isocaloric ingestion of amino acids or whey protein. Experimental Gerontology. Nov. 22., 2005

29. Paddon-Jones, D., Keech, A., Lonergan, A., Abernethy, P. Differential expression of muscle

damage in humans following acute fast and slow velocity eccentric exercise. J Sci. and Med. in Sports. Sep;8(3):255-63. 2005

30. Paddon-Jones, D., Sheffield-Moore, M., Urban, R.J., Aarsland, A., Wolfe, R.R. Ferrando, A.A. The catabolic effects of prolonged inactivity and acute hypercortisolemia are offset by dietary supplementation. J. Clin. Endocrinol Metab. 90(3):1453-9. 2005

31. Paddon-Jones, D., Sheffield-Moore, M., Aarsland, A., Wolfe, R.R., Ferrando, A.A. Exogenous

amino acids stimulate human muscle anabolism without interfering with the response to mixed meal ingestion. Am. J. Physiol. Endocrinol. Metab., 288(4):E761-7. 2005

32. Sheffield-Moore, M., Paddon-Jones, D., Sanford, A. P., Rosenblatt, J. I., Matlock, A. G., Cree,

M. G. and Wolfe, R.R. Mixed muscle and hepatic-derived plasma protein metabolism is


differentially regulated in older and younger men following resistance exercise. Am. J. Physiol. Endocrinol. Metab.,288(5):E922-9. 2005

33. Paddon-Jones, D., Sheffield-Moore, M., Urban, R.J., Sanford, A.P., Aarsland, A., Wolfe, R.R.

Ferrando, A.A. Essential amino acid and carbohydrate supplementation ameliorates muscle protein loss during 28 days bedrest. J. Clin. Endocrinol Metab. Sept. 2004

34. Sheffield-Moore, M., Yeckel, C. W., Volpi, E., Wolf, S. E., Morio, B., Chinkes, D. L., Paddon-

Jones, D. and Wolfe R. R. Post-exercise protein metabolism in older and younger men following moderate intensity aerobic exercise. Am. J. Physiol. Endocrinol. Metab., 287(3), E513-522, 2004

35. Paddon-Jones, D., Sheffield-Moore, M., Zhang X-J, Volpi, E., Wolf, S.E., Aarsland, A.,

Ferrando, A.A. and Wolfe, R.R. Amino acid ingestion improves muscle protein synthesis in the young and elderly. Am. J. Physiol. Endocrinol. Metab. Oct 28. 2003

36. Paddon-Jones, D., Sheffield-Moore, M., Creson, D.L., Wolf, S.E., Sanford, A.P., Wolfe, R.R.,

and Ferrando, A.A. Hypercortisolemia alters muscle protein anabolism following ingestion of essential amino acids. Am. J. Physiol. Endocrinol. Metab. Feb.4. 2003

37. Ferrando, A.A., Sheffield-Moore, M., Paddon-Jones, D., Wolfe, R.R., and Urban, R.J.

Differential anabolic effects of testosterone and amino acid feeding in older men. J. Clin. Endocrinol Metab. 88:358-362. 2003

38. Ferrando, A.A., Paddon-Jones, D., and Wolfe, R.R. Alterations in protein metabolism during

space flight and inactivity. Nutr. 18: 837-841. 2002 39. Rasmussen, B. Holmbäck, U., Volpi, E. Morio-Liondore, B. Paddon-Jones, D. and Wolfe. R.

Malonyl-CoA regulates functional carnitine palmitoyl-transferase I activity and fat oxidation in human skeletal muscle. J. Clin. Invest. 110: 1687-1693. 2002

40. Paddon-Jones, D., Keech, A. and Jenkins, D. Short term ß-hydroxy-ß-methylbutyrate

supplementation does not reduce symptoms of eccentric muscle damage. Int. J. Sports Nutr. 11 (4): 442-450. 2001

41. Paddon-Jones, D., Leveritt, M., Lonergan, A. and Abernethy, P. Adaptation to chronic

eccentric exercise in humans: the influence of contraction velocity. Eur. J. Appl. Physiol. 85: 466-471. 2001

42. Paddon-Jones, D. and Abernethy, P. Acute adaptation to low volume eccentric exercise. Med.

Sci. Sports Exerc. Jul; 33 (7): 1213-1219. 2001 43. Paddon-Jones, D., Muthalib, M. and Jenkins, D. The effects of a repeated bout of eccentric

exercise on indices of muscle damage and delayed onset muscle soreness. J. Sci. Med. Sport. 3(1):35-43. 2000

44. Paddon-Jones, D. and Pearson, D.R. The cost-effectiveness of pre-exercise carbohydrate

meals and their impact on endurance performance. J. Strength and Cond. Res. 12(2). 1998


45. Paddon-Jones, D. and Quigley, B.M. The effect of cryotherapy on muscle soreness and

strength following eccentric exercise. Int. J. Sports Med. 18(8). 1997


INVITED REVIEWS

1. Paddon-Jones, D., Cross-Bu, J.A., Phillips, S.M, Morris, C.R., Wernerman, J. Variation in protein origin and utilization: clinical application. Nutr. Clin. Practice. 32(1_suppl):48S-57S. 2017.

2. Phillips, S.M, Dickerson, R.N., Moore, F.A., Paddon-Jones, D., Weijs, P.J. Protein turnover and metabolism in the elderly ICU patient. Nutr. Clin. Practice. 32(1_suppl):112S-120S.

3. Rugeles SJ, Ochoa Gautier JB, Dickerson RN, Coss-Bu JA, Wernerman J, Paddon-Jones D. How Many Nonprotein Calories Does a Critically Ill Patient Require? A Case for Hypocaloric Nutrition in the Critically Ill Patient. Nutr Clin Pract. 2017 Apr;32(1_suppl):72S-76S.

4. Wernerman J, Morris CR, Paddon-Jones D, Sarav M. Assessment of Protein Turnover in Health and Disease. Nutr Clin Pract. 2017 Apr;32(1_suppl):15S-20S.

5. Hurt RT, McClave SA, Martindale RG, Ochoa Gautier JB, Coss-Bu JA, Dickerson RN, Heyland DK, Hoffer LJ, Moore FA, Morris CR, Paddon-Jones D, Patel JJ, Phillips SM, Rugeles SJ, Sarav Md M, Weijs PJ, Wernerman J, Hamilton-Reeves J, McClain CJ, Taylor B. Summary Points and Consensus Recommendations From the International Protein Summit. Nutr Clin Pract. 2017 Apr;32(1_suppl):142S-151S.

6. Galvan, E., Arentson-Lantz, E.J., Lamon, S., Paddon-Jones, D. Protecting Skeletal Muscle with Protein and Amino Acid during Periods of Disuse. Nutrients. 8(7), 2016

7. Paddon-Jones, D., Campbell, W.W., Jacques, P., Kritchevsky, S.B., Moore, L., Rodriguez, N., van Loon, L.C.J. Protein and Healthy Aging. Am. J. Clin. Nutr. 101 (6S), 1339-1335 2015

8. Arentson-Lantz, E., Clairmont, S, Paddon-Jones, D., Tremblay, A., Elango, R. Protein: A nutrient in focus. Appl Physiol Nutr Metab. Aug;40(8):755-61. 2015

9. Paddon-Jones, D. and Leidy, H. Protein and muscle in older persons. Curr. Opin. Clin. Nutr. Metab. Care. 17(1):5-11. 2013

10. English, K. and Paddon-Jones, D. Protecting muscle mass and function in older adults during bed rest. Curr. Opin. Clin. Nutr. Metab. Care. 13(1):34-39. 2010

11. Paddon-Jones, D. and Rasmussen,B.B. The Role of Protein Intake on the Preservation of Muscle Mass in Aging. Curr. Opin. Clin. Nutr. Metab. Care. Jan;12(1):86-90. 2009

12. Paddon-Jones, D., Short, K.R., Campbell, W.W., Garlick, P.J., Volpi, E., Wolfe, R.R. The role

of dietary protein in the sarcopenia of aging. Am. J. Clin. Nutr. 87(5):1562S-1566S. 2008 13. Paddon-Jones, D., Westman, E., Mattes, R.D., Wolfe, R.R., Astrup, A.A., Westerterp-

Plantenga, M.. Protein, weight management and satiety. Am. J. Clin. Nutr. 87(5):1558S-1561S. 2008


14. Paddon-Jones, D. Interplay of stress and physical inactivity on muscle loss: nutritional countermeasures. Recent Advances in Nutritional Sciences. J. Nutr. Aug;136(8):2123-6. 2006

15. Sheffield-Moore M., Paddon-Jones, D. and Urban, R.J. Amino Acid Supplementation and

Skeletal Muscle Metabolism in Adults. Hormone Research. 66 Suppl 1:93-7. 2006 16. Ferrando, A.A., Paddon-Jones, D. and Wolfe, R.R. Bedrest and myopathies. Current Opin.

Clin Nutr & Critical Care. Jul;9(4):410-5. 2006 17. Paddon-Jones, D., Wolfe, R.R and Ferrando, A.A. Amino acid supplementation for reversing

bedrest and steroid myopathies. J. Nutr. 135(7):1809-1812, 2005 18. Paddon-Jones, D., Børsheim, E., Wolfe, R.R. Potential ergogenic effects of arginine and

creatine supplementation. J. Nutr. 134:2888S-2894S, 2004 19. Casiano, E., Paddon-Jones, D., Ostir, G., and Sheffield-Moore, M. Essential Components of

Functional Status Tests: A Guide for Healthcare Professionals. Phys. Ther. Reviews. 7: 2002

B. BOOK CHAPTERS / LETTERS

1. [editorial] Paddon-Jones, D. Protein Recommendations for Bodybuilders: In This Case,

More May Indeed Be Better. J. Nutr. 2017 Mar 15. 2017

2. [letter] Arentson-Lantz E., English KL, Paddon-Jones D., Fry CS. The intersection of disuse-induced muscle atrophy and satellite cell content: reply to Snijders, Nederveen, and Parise. J.Appl.Physiol. 120. 12, 1491. 2016

3. [letter] Phillips, S.M., Tipton, K.D., van Loon, L.J.C., Verdijk, L.B., Paddon-Jones, D., Close, G.L. Exceptional body composition changes attributed to collagen peptide supplementation and resistance training in older sarcopenic men. Letter to the Editor. British J. Nutr. 116(3):569-70. 2016

4. Paddon-Jones, D., and Russell, A. Functional Status and Physical Activity in Older Adults Handbook of Clinical Nutrition and Aging, 3E, (Bales, Locher, and Saltzman eds) 2014

5. Paddon-Jones, D., and Van Loon, L. Nutritional Approaches to Prevent Sarcopenia. Sarcopenia. Wiley Publishers. (Cruz-Jentoft and Morley eds). 2012

6. Sheffield-Moore, M., Paddon-Jones, D. and Urban, R.J. Amino acid supplementation and skeletal muscle metabolism in adults. Hormone Research. 66 (Suppl. 1):93-97 2006

7. Sheffield-Moore M., Paddon-Jones D., Cree M. G., Lackan, D. W. and Urban, R. J. Effect of

Androgens on Muscle, Bone, and Hair in Men. In: Tan RS (ed.). Aging Men's Health. New York: Thieme Medical Publishers; 83-93: 2005


C. SELECTED INVITED PRESENTATIONS / KEY NOTE ADDRESSES 1. South East Asia Dairy Conference. Singapore, December 2016 2. Protein Think Tank. Chicago. October, 2016 3. American Dairy Association/ Wegmans Protein Symposium. NY. October, 2016 4. St. Luke’s Hospital Grand Rounds, Boise Idaho. October 2016 5. Idaho Pressure Ulcer Prevention Coalition. Boise Idaho. October 2016 6. Alpha Protein Summit, Singapore, October 2016 7. International Egg Nutrition, Functional Food and Human Health Symposium, Banff, Oct 2016 8. International Protein Summit, Protein in the ICU. Nestle. Charleston SC. September, 2016 9. Sports nutrition symposium. Boise, Idaho. August, 2016 10. US Dairy Export Council Key Note Seminar. Denpasar, Bali. August 2016 11. ACSM. Dietary Protein in Support of Exercise Adaptations and Health. Boston. June 2016 12. Live Well Conference. Austin Tx. April, 2016 13. Research Symposium Keynote Address. Louisiana State University HSC. March, 2016 14. NEP Seminar Series, University of Missouri. February 2016 15. AND-FNCE Annual Meeting. Nashville. October, 2015 16. Gerontological Advanced Practice Nurses Association. San Antonio, September, 2015 17. Institute of Food Technologists Annual Meeting & Food Expo. Chicago, July, 2015 18. Asian Congress of Nutrition, Yokohama, Japan. May, 2015 19. International Conference on Frailty & Sarcopenia Research. Boston. April, 2015 20. Idaho Academy of Nutrition and Dietetics Annual Meeting. Boise. April, 2015 21. Oklahoma State University, Health and Wellness Symposium. April, 2015 22. Gerontological Society of America Annual Meeting. Washington DC. November, 2014 23. Enhanced Recovery after Surgery (ERAS) symposium. Edmonton CA. October, 2014 24. Nestlé Nutrition Institute, Commonwealth Scientific and Industrial Research Organization

(CSIRO) and Australasian Society for Parenteral and Enteral Nutrition (AUSPEN) symposium. Melbourne, Australia. October, 2014

25. 7th International Whey Conference. Rotterdam. September, 2014 26. Chinese Nutrition Society Annual Meeting. Shanghai. June, 2014 27. American College of Sports Medicine. Florida. May, 2014 28. 11th Nutrition and Health: State of the Science. University of Arizona. April, 2014 29. Texas Academy of Nutrition and Dietetics Annual Meeting. Corpus Christi. April, 2014 30. Colorado Academy of Nutrition and Dietetics Annual Meeting. Denver. April, 2014 31. Dairy Farmers of Canada Symposium on Nutrition and Health. Edmonton, Toronto, Moncton,

Montreal. December, 2013 32. Culinary Institute of America. New York. October, 2013 33. Protein Summit 2.0. Washington DC. October, 2013 34. American Assn. of Nurse Practitioners. National Conference. Las Vegas. June, 2013. 35. Steve Nissan Honorary Seminar, Iowa State University, May, 2013 36. Canadian Nutrition Society Annual Meeting, Montreal. May, 2013 37. First Caribbean Nutrition Summit, Dominican Republic. May 2013


38. 4th World Congress on Exercise is Medicine. Indianapolis. April, 2013 39. Nebraska Dietetic Association Annual Meeting. Overland Park, April, 2013 40. West Virginia Dietetic Association Annual Meeting. Marshall University, March, 2013 41. Nutrition Obesity Research Center (NORC), University of Alabama, Feb, 2013 42. US Dairy Export Council Key Note Seminar, Japan and Korea, November, 2012 43. ADA-FNCE Annual Meeting. Philadelphia, PA, October, 2012 44. SANCYD Congress. Seville, Spain. March, 2012 45. Sports, Cardiovascular Wellness and Nutrition Annual Conf., Baltimore, April 2012 46. British Association for Parenteral and Enteral Nutrition, Annual Conference. Nov. 2011 47. Dietetic Forum. Culinary Institute of America, Hyde Park, NY. October, 2011 48. Spanish Society of Enteral and Parental Nutr. Annual Meeting, Girona, Spain. May 2011 49. Californian Society of Enteral and Parental Nutr. Los Angeles, May 2011 50. Rhode Island Dietetic Association, April 2011 51. EUGMS Dublin, Ireland, September 2010 52. US Dairy Export Council Key Note Seminar, Shanghai, China, September 2010 53. European Society of Enteral and Parenteral Nutrition (ESPEN), Nice, France. Aug 2010 54. Southern California Society of Enteral and Parental Nutrition, July, 2010 55. Institute of Food Technologists Annual Meeting & Food Expo. Chicago, July 2010 56. Utah Dietetic Association Annual Meeting, Ogden, UT. April 2010 57. Kentucky Dietetic Association Annual Meeting, Bowling Green, KY. April 2010 58. Iowa Dietetic Association Annual Meeting, Altoona, IA. November 2009 59. Abbott Nutrition Research Conference, Columbus OH, June 2009 60. USDA Seminar Program. Baltimore, MD. May 2009 61. Nebraska Dietetic Association Annual Meeting. Lincoln NB. April 2009 62. Missouri Dietetic Association Annual Meeting. Branson MZ. April 2009 63. American Society of Bariatric Physicians, Annual Meeting. Charleston, SC. April 2009 64. Texas Academy of Cardiovascular Pulmonary Rehab. Annual Meeting. March 2009 65. American Dietetic Assoc., Food & Nutrition Conference. Chicago, IL. October 2008 66. Protein Metabolism and Nutrition, Florida Dietetic Association, September 2008 67. Protein Think Tank and Summit, Seattle, WA September 2008 68. A Nutrition Adventure: Explore the Power of Protein, Kansas City, MO. May 2008 69. New Jersey Dietetic Association Annual Meeting, New Brunswick, NJ. May 2008 70. Nutrition & Aging XXII: Frailty in Older Adults. Little Rock, AR September 2007. 71. US Dairy Export Council Seminar Series. Singapore, Jakarta, Surabaya. September 2007 72. Florida Dietetic Association Annual Meeting. San Marco Island. Fl. July 2007 73. Idaho Academy of Family Physicians, Annual Meeting. Boise, ID, May 2007 74. Texas Academy of Family Physicians, Scientific Assembly. Corpus Christi, July 2007 75. Weight Management Dietetic Practice Group, Annual Meeting. Scottsdale, May 2007 76. Sports, Cardiovascular and Wellness Nutrition Dietetic Practice Group Awards Luncheon and

Annual Symposium. Austin , TX, April 2007 77. Grand Rounds. St. Luke’s Hospital, Boise, ID. April, 2007 78. Ground Rounds. Mercy Medical Center, Nampa, ID. April, 2007


79. Ground Rounds. Boise VA Hospital, Boise ID. April, 2007 80. Annual Physician Assistant Meeting, Sun Valley, ID. April, 2007 81. Clinical Nutrition Management Dietetic Practice Group (ADA). Tampa FL. March 2007 82. Live Well 2006: A Toast to the Senses and Science. Napa Valley. June, 2006 83. American Dietetic Association Nutrition News Forecast. Vancouver, May, 2006 84. Idaho Dairy Council, Annual Dietetic Conference. Idaho Falls, April, 2006 85. Grand Rounds, Eastern Idaho Regional Medical Center. Idaho Falls, April, 2006 86. Nutrition Research Discovery Symposium. Denver, CO. April, 2006

curriculum vitae - shp › cv › paddon-jones_d-cv.pdf · curriculum vitae name: douglas...

Documents