cumc dermatopathology publications 2006-2009

7/29/2019 Cumc Dermatopathology Publications 2006-2009

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CUMC DermatopathologyCUMC Dermatopathology

publications,2006 - 2009publications,2006 - 2009

Deba P Sarma, MDDeba P Sarma, MD

Professor of PathologyProfessor of Pathology

Director of DermatopathologyDirector of Dermatopathology

Creighton University Medical Center, Omaha, NECreighton University Medical Center, Omaha, NE


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Man, 58, with a tumor mass in the leg amputation stump

.

Ref:

Deba P. Sarma, Thomas P. Hansen, Edward D. Adickes:

Carcinoma Arising In The Leg Amputation Stump

. The Internet Journal of Dermatology.2006. Volume 4 Number 1.

Diagnosis: Verrucous carcinoma

Fig.1Fig.2
http://www.ispub.com/ostia/index.php?xmlFilePath=journals/ijd/vol4n1/leg.xmlhttp://www.ispub.com/ostia/index.php?xmlFilePath=journals/ijd/vol4n1/leg.xmlhttp://www.ispub.com/ostia/index.php?xmlFilePath=journals/ijd/vol4n1/leg.xmlhttp://www.ispub.com/ostia/index.php?xmlFilePath=journals/ijd/vol4n1/leg.xmlhttp://www.ispub.com/ostia/index.php?xmlFilePath=journals/ijd/vol4n1/leg.xmlhttp://www.ispub.com/ostia/index.php?xmlFilePath=journals/ijd/vol4n1/leg.xml


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Male, 41, presented with disseminated subcutaneous abscesses oneMale, 41, presented with disseminated subcutaneous abscesses one

month after amputation for septic right leg and removal of Groshonmonth after amputation for septic right leg and removal of Groshon

vascular catheter tip.vascular catheter tip.

Fig.1Fig.2

Fig,3, AFB stain

Diagnosis: Dermal abscess due to

Mycobacterium abscessus.

Ref.

Hansen TP, Sarma DP(2006): Multiple subcutaneous nodules associate with Mycobacterium

abscessus infection following removal of an infectedGroshonvascular catheter tip.Dermatol

Online J 12(4):12. PMID:17083867 [PubMed- indexed for MEDLINE]
http://dermatology.cdlib.org/124/case_presentations/mycobacteria/hansen.htmlhttp://dermatology.cdlib.org/124/case_presentations/mycobacteria/hansen.htmlhttp://dermatology.cdlib.org/124/case_presentations/mycobacteria/hansen.htmlhttp://dermatology.cdlib.org/124/case_presentations/mycobacteria/hansen.htmlhttp://dermatology.cdlib.org/124/case_presentations/mycobacteria/hansen.htmlhttp://dermatology.cdlib.org/124/case_presentations/mycobacteria/hansen.htmlhttp://dermatology.cdlib.org/124/case_presentations/mycobacteria/hansen.htmlhttp://dermatology.cdlib.org/124/case_presentations/mycobacteria/hansen.htmlhttp://dermatology.cdlib.org/124/case_presentations/mycobacteria/hansen.htmlhttp://dermatology.cdlib.org/124/case_presentations/mycobacteria/hansen.htmlhttp://dermatology.cdlib.org/124/case_presentations/mycobacteria/hansen.htmlhttp://dermatology.cdlib.org/124/case_presentations/mycobacteria/hansen.htmlhttp://dermatology.cdlib.org/124/case_presentations/mycobacteria/hansen.htmlhttp://dermatology.cdlib.org/124/case_presentations/mycobacteria/hansen.htmlhttp://dermatology.cdlib.org/124/case_presentations/mycobacteria/hansen.htmlhttp://dermatology.cdlib.org/124/case_presentations/mycobacteria/hansen.htmlhttp://dermatology.cdlib.org/124/case_presentations/mycobacteria/hansen.html


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Man, 29, with a painless slow-growing nodule of left forearmMan, 29, with a painless slow-growing nodule of left forearm

for a year.for a year.Fig.1

Fig.2

Diagnosis: Sinusoidal hemangioma.

Ref.

Wang B, Santos E, Sarma DP(2006). Sinusoidalhemangioma

in an adult male. The Internet JDermatol. 4(1):2006. Indexed by

Google Scholar.
http://www.ispub.com/ostia/index.php?xmlFilePath=journals/ijd/vol4n1/hemangio.xmlhttp://www.ispub.com/ostia/index.php?xmlFilePath=journals/ijd/vol4n1/hemangio.xmlhttp://www.ispub.com/ostia/index.php?xmlFilePath=journals/ijd/vol4n1/hemangio.xmlhttp://www.ispub.com/ostia/index.php?xmlFilePath=journals/ijd/vol4n1/hemangio.xmlhttp://www.ispub.com/ostia/index.php?xmlFilePath=journals/ijd/vol4n1/hemangio.xmlhttp://www.ispub.com/ostia/index.php?xmlFilePath=journals/ijd/vol4n1/hemangio.xmlhttp://www.ispub.com/ostia/index.php?xmlFilePath=journals/ijd/vol4n1/hemangio.xmlhttp://www.ispub.com/ostia/index.php?xmlFilePath=journals/ijd/vol4n1/hemangio.xmlhttp://www.ispub.com/ostia/index.php?xmlFilePath=journals/ijd/vol4n1/hemangio.xmlhttp://www.ispub.com/ostia/index.php?xmlFilePath=journals/ijd/vol4n1/hemangio.xml


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Man, 59, phimosis, excised foreskin.Man, 59, phimosis, excised foreskin.

Fig.1 Fig.2

Diagnosis: Hemangioma.

Ref. Santos E, Sarma D(2006): Hemangiomaof the prepuce. TheInternetJ

Dermatol.4(1). Indexed by Google Scholar.
http://www.ispub.com/ostia/index.php?xmlFilePath=journals/ijd/vol4n1/prepuce.xmlhttp://www.ispub.com/ostia/index.php?xmlFilePath=journals/ijd/vol4n1/prepuce.xmlhttp://www.ispub.com/ostia/index.php?xmlFilePath=journals/ijd/vol4n1/prepuce.xmlhttp://www.ispub.com/ostia/index.php?xmlFilePath=journals/ijd/vol4n1/prepuce.xmlhttp://www.ispub.com/ostia/index.php?xmlFilePath=journals/ijd/vol4n1/prepuce.xmlhttp://www.ispub.com/ostia/index.php?xmlFilePath=journals/ijd/vol4n1/prepuce.xmlhttp://www.ispub.com/ostia/index.php?xmlFilePath=journals/ijd/vol4n1/prepuce.xmlhttp://www.ispub.com/ostia/index.php?xmlFilePath=journals/ijd/vol4n1/prepuce.xml


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Man,74, 1-cm keratotic lesion of foreheadMan,74, 1-cm keratotic lesion of forehead

Fig.1Fig.2

Diagnosis: Bullous actinic keratosis

Ref.

Sarma DP, Sharma P(2006) Bulloussolarkeratosis. The Internet JDermatol, 4(1). Indexed by Google Scholar.
http://www.ispub.com/ostia/index.php?xmlFilePath=journals/ijd/vol4n1/bullous.xmlhttp://www.ispub.com/ostia/index.php?xmlFilePath=journals/ijd/vol4n1/bullous.xmlhttp://www.ispub.com/ostia/index.php?xmlFilePath=journals/ijd/vol4n1/bullous.xmlhttp://www.ispub.com/ostia/index.php?xmlFilePath=journals/ijd/vol4n1/bullous.xmlhttp://www.ispub.com/ostia/index.php?xmlFilePath=journals/ijd/vol4n1/bullous.xmlhttp://www.ispub.com/ostia/index.php?xmlFilePath=journals/ijd/vol4n1/bullous.xmlhttp://www.ispub.com/ostia/index.php?xmlFilePath=journals/ijd/vol4n1/bullous.xmlhttp://www.ispub.com/ostia/index.php?xmlFilePath=journals/ijd/vol4n1/bullous.xmlhttp://www.ispub.com/ostia/index.php?xmlFilePath=journals/ijd/vol4n1/bullous.xmlhttp://www.ispub.com/ostia/index.php?xmlFilePath=journals/ijd/vol4n1/bullous.xmlhttp://www.ispub.com/ostia/index.php?xmlFilePath=journals/ijd/vol4n1/bullous.xml


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Man,69, left cheek lesion, suspected of squamous cell carcinoma

Fig.1 Fig.2

The tumor cells were immunoreactive for EMA, BerEp-4, CK7, and, AE1/3 with variable positive stains of Androgen receptor,

CK8/18, and Vimentin, but were negative for immunostains of S100, HMB45, CK20, TTF-1, RCC, and PSA. The neoplastic cells

from the foci of apocrine differentiation were immunoreactive for GCDFP-15 and CK8/18. Immunostains for mismatch repair genes

includnig hMLH1, hMSH2, hMSH6, PMSH2 and RT-PCR for microsatellite instability studies including MSI (T) and MSI(C) were

negative.

Diagnosis: Sebaceous carcinoma with apocrine differentiation

Ref.

Wang B, Sarma DP(2006). Sebaceous carcinoma withapocrinedifferentiation. The Internet J

Dermatol, 4(2). Indexed by Google Scholar.
http://www.ispub.com/ostia/index.php?xmlFilePath=journals/ijd/vol4n2/apocrine.xmlhttp://www.ispub.com/ostia/index.php?xmlFilePath=journals/ijd/vol4n2/apocrine.xmlhttp://www.ispub.com/ostia/index.php?xmlFilePath=journals/ijd/vol4n2/apocrine.xmlhttp://www.ispub.com/ostia/index.php?xmlFilePath=journals/ijd/vol4n2/apocrine.xmlhttp://www.ispub.com/ostia/index.php?xmlFilePath=journals/ijd/vol4n2/apocrine.xmlhttp://www.ispub.com/ostia/index.php?xmlFilePath=journals/ijd/vol4n2/apocrine.xmlhttp://www.ispub.com/ostia/index.php?xmlFilePath=journals/ijd/vol4n2/apocrine.xmlhttp://www.ispub.com/ostia/index.php?xmlFilePath=journals/ijd/vol4n2/apocrine.xmlhttp://www.ispub.com/ostia/index.php?xmlFilePath=journals/ijd/vol4n2/apocrine.xmlhttp://www.ispub.com/ostia/index.php?xmlFilePath=journals/ijd/vol4n2/apocrine.xml


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Woman, 51, 1-cm nodule, left armWoman, 51, 1-cm nodule, left arm

Diagnosis: Proliferating trichilemmal cyst

Ref.

Sharma P, Sarma DP(2006). Proliferatingtrichilemmal

cyst of the arm. The Internet J Dermatol,4(2), 2006. Indexed by Google Scholar.
http://www.ispub.com/ostia/index.php?xmlFilePath=journals/ijd/vol4n2/cyst.xmlhttp://www.ispub.com/ostia/index.php?xmlFilePath=journals/ijd/vol4n2/cyst.xmlhttp://www.ispub.com/ostia/index.php?xmlFilePath=journals/ijd/vol4n2/cyst.xmlhttp://www.ispub.com/ostia/index.php?xmlFilePath=journals/ijd/vol4n2/cyst.xmlhttp://www.ispub.com/ostia/index.php?xmlFilePath=journals/ijd/vol4n2/cyst.xmlhttp://www.ispub.com/ostia/index.php?xmlFilePath=journals/ijd/vol4n2/cyst.xml


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cheek.cheek.

Diagnosis: Squamous cell carcinoma in situ associated with osteoma cutis.

Poonam Sharma, Deba P. Sarma: Squamous Cell Carcinoma In Situ Associated With

Osteoma Cutis. The Internet Journal of Dermatology. 2006. Volume 4 Number

Ref.


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An 80-year-old man presented with a long-standing skin lesion on his mid forehead.An 80-year-old man presented with a long-standing skin lesion on his mid forehead.

Diagnosis: Seborrheic keratosis with in-situ squamous cell carcinoma changes

Ref.

Sharma P, Sarma DP, Adickes ED (2006). Seborrheickeratosis

with in-situ carcinoma changes. Dermatology Online J 12(7):19. PMID: 17459305

[PubMed - indexed for MEDLINE]
http://dermatology.cdlib.org/127/case_presentations/scc/sharma.htmlhttp://dermatology.cdlib.org/127/case_presentations/scc/sharma.htmlhttp://dermatology.cdlib.org/127/case_presentations/scc/sharma.htmlhttp://dermatology.cdlib.org/127/case_presentations/scc/sharma.htmlhttp://dermatology.cdlib.org/127/case_presentations/scc/sharma.htmlhttp://dermatology.cdlib.org/127/case_presentations/scc/sharma.html


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A few interesting memories from more than 30-year of dermatopathology practice

Deba P. Sarma: From The Diary Of A Dermatopathologist. The Internet

Journal of Dermatology. 2006. Volume 4 Number 2.

year o man w t a year story o a etes me tusyear o man w a year s ory o a e es me us


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-year-o man w t a -year story o a etes me tus,-year-o man w a -year s ory o a e es me us,peripheral vascular disease and hypertension presented with a non-peripheral vascular disease and hypertension presented with a non-

healing ulcer of left foothealing ulcer of left foot

Diagnosis: Verrucous carcinoma.

Ref.

Deba P. Sarma, Jeff F. Wang, Chhanda Bewtra, Lisa M. J. Lee: Verrucous Carcinoma

Arising In A Chronic Non-Healing Ulcer Of The Foot Of A Diabetic Patient. The

Internet Journal of Dermatology. 2007. Volume 5 Number 1.

year o ema e presen e a cm a p gmen e s n es on on e r g orsayear o ema e presen e a cm a p gmen e s n es on on e r g orsa


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-year-o ema e presen e a . cm a , p gmen e s n es on on e r g orsa-year-o ema e presen e a . cm a , p gmen e s n es on on e r g orsa

forearm.forearm.

Melan A stain S-100 stain

Diagnosis: Pigmented neurofibroma.

Ref.

Zenggang Pan, Deba P. Sarma: Pigmented Neurofibroma Of The Skin: A Case Report And

Review Of The Literature. The Internet Journal of Dermatology. 2007. Volume 5 Number 1.


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A 34-year-old woman noticed multiple slow-growing painful and itchy nodules on

her face (1 lesion) and extremities(1 on arm and 5 on both legs).

Diagnosis: Dermatofibroma.

Ref.

Mingkui Chen, Deba Sarma: Multiple Dermatofibromas in an Adult Female. The



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Abstract

We report a case of dermal malignant melanoma that stained negatively for commonly

done immunostains, HMB-45, and Melan-A. It stained weakly positive for S-100 protein,

a less specific marker for melanocytes. The diagnosis was established by strongly

positive immunostaining by MITF ( microphthlmia-associated transcription factor). A brief

review of the MITF and its usefulness in the diagnosis of melanoma are presented.

MITF

Ref.

Jeff F. Wang, Deba P. Sarma, Pamela Ulmer: Diagnostic dilemma: HMB-45 and

Melan-A negative tumor, can it be still a melanoma?: MITF (Microphthalmia-

associated transcription factor) stain may confirm the diagnosis. The Internet



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AbstractA benign adnexal skin tumor showing sebaceous and hair

differentiation occurring in an 84-year-old man is reported.Such a tumor may be called a sebotrichoma.

Diagnosis: Sebotrichoma

Ref.

Sarma DP, Santos EE, Wang B (2007). Sebotrichoma. The Internet JDermatol

5(1). Indexed by Google Scholar.

Ab t t
http://www.ispub.com/ostia/index.php?xmlFilePath=journals/ijd/vol5n1/sebo.xmlhttp://www.ispub.com/ostia/index.php?xmlFilePath=journals/ijd/vol5n1/sebo.xmlhttp://www.ispub.com/ostia/index.php?xmlFilePath=journals/ijd/vol5n1/sebo.xmlhttp://www.ispub.com/ostia/index.php?xmlFilePath=journals/ijd/vol5n1/sebo.xmlhttp://www.ispub.com/ostia/index.php?xmlFilePath=journals/ijd/vol5n1/sebo.xmlhttp://www.ispub.com/ostia/index.php?xmlFilePath=journals/ijd/vol5n1/sebo.xmlhttp://www.ispub.com/ostia/index.php?xmlFilePath=journals/ijd/vol5n1/sebo.xml


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Abstract

A skin biopsy from a nasal lesion showed a dermal infiltrating neoplasm composed of

polygonal cells with small nuclei and abundant coarsely granular eosinophilic cytoplasm.

Light microscopic features were that of a granular cell tumor. However, the results of the

immunohistologic studies and the observations of the electron microscopic studies did

not identify the nature of the cells nor did they confirm that it was a granular cell tumor.We interpret the lesion as a pseudogranular cell tumor of the skin.

Deba P. Sarma, Eric E. Santos, William J. Hunter, Zoran Gatalica: Pseudogranular

Cell Tumor Of The Skin. The Internet Journal of Dermatology. 2007. Volume 5 Number

1.

Ref.

Diagnosis: Pseudogranular cell tumor


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A case of acquired perforating osteoma cutis occurring on theA case of acquired perforating osteoma cutis occurring on the

finger of a 43-year-old man is reported. English literature onfinger of a 43-year-old man is reported. English literature on

the topic is briefly reviewed.the topic is briefly reviewed.

Diagnosis: Osteoma cutis

Ref.

Wang JF, Sarma DP (2007).Acquired perforatingosteoma

cutis. The Internet JDermatol5(1). Indexed by Google Scholar.
http://www.ispub.com/ostia/index.php?xmlFilePath=journals/ijd/vol5n1/osteoma.xmlhttp://www.ispub.com/ostia/index.php?xmlFilePath=journals/ijd/vol5n1/osteoma.xmlhttp://www.ispub.com/ostia/index.php?xmlFilePath=journals/ijd/vol5n1/osteoma.xmlhttp://www.ispub.com/ostia/index.php?xmlFilePath=journals/ijd/vol5n1/osteoma.xmlhttp://www.ispub.com/ostia/index.php?xmlFilePath=journals/ijd/vol5n1/osteoma.xmlhttp://www.ispub.com/ostia/index.php?xmlFilePath=journals/ijd/vol5n1/osteoma.xmlhttp://www.ispub.com/ostia/index.php?xmlFilePath=journals/ijd/vol5n1/osteoma.xmlhttp://www.ispub.com/ostia/index.php?xmlFilePath=journals/ijd/vol5n1/osteoma.xmlhttp://www.ispub.com/ostia/index.php?xmlFilePath=journals/ijd/vol5n1/osteoma.xmlhttp://www.ispub.com/ostia/index.php?xmlFilePath=journals/ijd/vol5n1/osteoma.xml


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AbstractAbstract

We are reporting a case of cutaneous leiomyosarcomaWe are reporting a case of cutaneous leiomyosarcoma

occurring on the face of a 98-year-old woman with a briefoccurring on the face of a 98-year-old woman with a brief

review of the literaturereview of the literature..

Diagnosis: Leiomyosarcoma cutis.

Ref.

Eric E. Santos, Deba P. Sarma: Cutaneous Leiomyosarcoma of the Face. The


SMA stain


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I find no good reason to separate keratoacanthoma from well differentiated

squamous cell carcinoma. I am now reporting crateriform squamous

epithelial lesions (that I used to report as keratoacanthoma) as well

differentiated squamous cell carcinoma, keratoacanthoma type'. They may

then be treated as a well differentiated squamous cell carcinoma with asuperficial complete resection, and the patient is relieved of a fast-growing

lesion. A small scar is definitely acceptable!

Ref.

Deba P. Sarma: Keratoacanthoma Should Be Reported As 'Well

Differentiated Squamous Cell Carcinoma, Keratoacanthoma Type': A

Dermatopathologist's View. The Internet Journal of Dermatology. 2007.

Volume 5 Number 1.


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The picture is that of the palms of a 44-year old man of Chinese heritage who

had had red hands since birth. His 74-year-old mother and his 7-year-old

daughter also had bright red palms all their life.

Diagnosis: Erythema palmare hereditarium

Sarma DP, Wang B (2007). Erythemapalmarehereditarium

(Red palms): Lanes Disease.DermatolOnline J. 13(2). PMID: 17498447

[PubMed - indexed for MEDLINE

Ref
http://dermatology.cdlib.org/132/letters/erythema/sarma.htmlhttp://dermatology.cdlib.org/132/letters/erythema/sarma.htmlhttp://dermatology.cdlib.org/132/letters/erythema/sarma.htmlhttp://dermatology.cdlib.org/132/letters/erythema/sarma.htmlhttp://dermatology.cdlib.org/132/letters/erythema/sarma.htmlhttp://dermatology.cdlib.org/132/letters/erythema/sarma.htmlhttp://dermatology.cdlib.org/132/letters/erythema/1.jpghttp://dermatology.cdlib.org/132/letters/erythema/sarma.htmlhttp://dermatology.cdlib.org/132/letters/erythema/sarma.htmlhttp://dermatology.cdlib.org/132/letters/erythema/sarma.htmlhttp://dermatology.cdlib.org/132/letters/erythema/sarma.htmlhttp://dermatology.cdlib.org/132/letters/erythema/sarma.htmlhttp://dermatology.cdlib.org/132/letters/erythema/sarma.html


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Abstract

A case of a wooden splinter dermatitis occurring in the foot of a 69-year old female is

reported. The clinical features, pathology and treatment of this common injury are

briefly reviewed.

Ref.

Chen M, Sarma DP (2007). Wooden splinter dermatitis. The Internet J

Dermatol5(2). Indexed by Google Scholar.

Diagnosis: Wooden splinter dermatitis
http://scholar.google.com/scholar?hl=en&lr=&cluster=18433840759810380733http://scholar.google.com/scholar?hl=en&lr=&cluster=18433840759810380733http://scholar.google.com/scholar?hl=en&lr=&cluster=18433840759810380733http://scholar.google.com/scholar?hl=en&lr=&cluster=18433840759810380733http://scholar.google.com/scholar?hl=en&lr=&cluster=18433840759810380733http://scholar.google.com/scholar?hl=en&lr=&cluster=18433840759810380733


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AbstractCutaneous ossification is as a primary event or secondary

to a wide variety of inflammatory, traumatic, orneoplastic conditions. We describe a case ofpilomatricoma with extensive ossification

Ref.

Sharma P, Sarma DP (2007). Ossifiedpilomatricoma. The Internet JDermatol


Diagnosis: Ossified pilomatricoma

Abstract
http://www.ispub.com/ostia/index.php?xmlFilePath=journals/ijd/vol5n2/pilo.xmlhttp://www.ispub.com/ostia/index.php?xmlFilePath=journals/ijd/vol5n2/pilo.xmlhttp://www.ispub.com/ostia/index.php?xmlFilePath=journals/ijd/vol5n2/pilo.xmlhttp://www.ispub.com/ostia/index.php?xmlFilePath=journals/ijd/vol5n2/pilo.xmlhttp://www.ispub.com/ostia/index.php?xmlFilePath=journals/ijd/vol5n2/pilo.xmlhttp://www.ispub.com/ostia/index.php?xmlFilePath=journals/ijd/vol5n2/pilo.xmlhttp://www.ispub.com/ostia/index.php?xmlFilePath=journals/ijd/vol5n2/pilo.xmlhttp://www.ispub.com/ostia/index.php?xmlFilePath=journals/ijd/vol5n2/pilo.xmlhttp://www.ispub.com/ostia/index.php?xmlFilePath=journals/ijd/vol5n2/pilo.xml


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AbstractCaucasian female. A brief review of the literature is presented.We report a case of a Merkel cell carcinoma of the dermis with a Bowen's

disease of the overlying epidermis arising in the left thigh in an 88-year-old

CK20

Ref.

Deba P. Sarma, Bo Wang, James Shehan, Lisa Linder-Stephenson: Concurrent

Merkel cell carcinoma and Bowen's disease of the thigh. The Internet Journal of

Dermatology. 2007. Volume 5 Number 2.


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AbstractWe report a case of metatypical basal cell carcinoma on thenose of a 79-year-old woman with a briefreview of theliterature

Ber-Ep4

bcl2

Ref.

Eric E. Santos, Deba P. Sarma, Mingkui Chen, Bo Wang: Metatypical Basal

Cell Carcinoma of the Nose. The Internet Journal of Dermatology. 2007. Volume

5 Number

Diagnosis: Metatypical basal cell carcinoma

Abstract


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Abstract

Fibrofolliculoma is a very rare benign tumor of the skin that is derived from the

perifollicular sheath. Histologically, it shows a well-formed central hair follicle with a

dilated infundibulum containing laminated keratin with anastomosing epithelial strands

that radiate from the central hair follicle into the perifollicular fibrotic stroma. The

patients with multiple fibrofolliculomas have an association with Birt-Hogg-Dubesyndrome. We report a case of a solitary nasal fibrofolliculoma occurring in a 60-year-

old male and briefly review the literature.

Ref.

Zenggang Pan, Deba P. Sarma: Solitary Nasal Fibrofolliculoma. The Internet


Diagnosis: Fibrofolliculoma

Abstract


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Abstract

A case of intramuscular angioma in the frontalis muscle of the forehead

is reported. The etiology, pathology and treatment of this rare tumor

are briefly reviewed.

Ref.

Mingkui Chen, Deba P. Sarma: Intramuscular Angioma of the

Frontalis Muscle. The Internet Journal of Dermatology. 2007. Volume5 Number 2.

Diagnosis: Intramuscular angioma.

We report a rare case of a dermal nerve sheath


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We report a rare case of a dermal nerve sheathmyxoma of the left intranasal skin occurring in a 33-year-old female. A brief review of nerve sheathmyxoma and a similar tumor, neurothekeoma, is

presented.

S-100

Ref.

Jeff F. Wang, Deba P. Sarma, Eric E. Santos, Bo Wang: Dermal Nerve Sheath

Myxoma. The Internet Journal of Dermatology. 2007. Volume 5 Number 2.

Diagnosis: Dermal nerve sheath myxoma


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AbstractMedical students and the trainees in dermatology and pathology have a curiosity about the names, such as,

acne vulgaris or verruca vulgaris. The word vulgaris sounds like vulgar, commonly meaning crudely

indecent, coarse, or obscene. However, the word vulgar is derived from the Latin word vulgaris, meaning

of or belonging to the common people. In medical terminology, the word vulgaris means common orordinary.

A search through the indexes in Dermatology and Pathology text books revealed seven dermatologic

conditions with vulgaris in their names. These included very common diseases, such as, acne vulgaris and

verruca vulgaris as well as now rarely diagnosed disease, such as, lupus vulgaris. We are briefly reviewing

the seven vulgaris diseases of the skin.

Ref.

Mingkui Chen, Erin Bruno, Eric E. Santos, Deba P. Sarma: A brief review of thevulgaris lesions of the skin. The Internet Journal of Dermatology. 2007. Volume

6 Number 1.

Ab t t


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AbstractWe present a case of an 81-year-old malewith an asymptomatic skin nodule on his leftupper cheek

Ref

Bo Wang, Deba P. Sarma: Sebaceous Carcinoma and Mismatch Repair Gene

Expression. The Internet Journal of Dermatology. 2007. Volume 6 Number 1


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Case Report

This is a photomicrograph (Figure 1) of a biopsied asymptomatic skin nodule from the anterior neck of

a 45-year-old man. There was no history of trauma or previous surgical procedure in this location. The

epidermis is somewhat raised with hyperkeratosis and acanthosis. The upper dermis shows fibrosis. A

well-circumscribed dermal tumor nodule shows no extension into the subcutis. The tumor is composed

of mature hyaline cartilage with normal chondrocytes within a homogeneous basophilic stroma. Thechondrocytes show mostly single small nuclei without any significant atypia (Figure 2). There is no

necrosis or mitotic figures. Secondary ossification or calcification is not present. The periphery of the

tumor is free of any giant cell reaction, granulation tissue or any evidence of traumatic tissue reaction.

The lesion appears to be a true chondroma in the dermis.

Ref

Deba P. Sarma, Mingkui Chen, Bo Wang: Chondroma Cutis. The Internet Journal

of Dermatology. 2007. Volume 6 Number 1.

Case presentation


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p

We report a case of a 59-year-old woman with a cutaneous

leiomyosarcoma associated with osteoclast-like giant cells arising from the

subcutaneous artery of the leg. The nature of the giant cells is discussed in

light of the findings from the immunostaining as well as survey of the

literature.

Ref.

Sarma DP, Santos EE, Wang B (2007). Leiomyosarcomaof the skin withosteoclast

-like giant cells: a case report. J Med Case Reports 1(1):108.

PMID: 18081931 [PubMed - in process

Abstract
http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&Cmd=ShowDetailView&TermToSearch=18081931&ordinalpos=1&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSumhttp://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&Cmd=ShowDetailView&TermToSearch=18081931&ordinalpos=1&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSumhttp://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&Cmd=ShowDetailView&TermToSearch=18081931&ordinalpos=1&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSumhttp://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&Cmd=ShowDetailView&TermToSearch=18081931&ordinalpos=1&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSumhttp://www.jmedicalcasereports.com/content/1/1/180/figure/F3?highres=yhttp://www.jmedicalcasereports.com/content/1/1/180/figure/F2?highres=yhttp://www.jmedicalcasereports.com/content/1/1/180/figure/F1?highres=yhttp://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&Cmd=ShowDetailView&TermToSearch=18081931&ordinalpos=1&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSumhttp://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&Cmd=ShowDetailView&TermToSearch=18081931&ordinalpos=1&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSumhttp://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&Cmd=ShowDetailView&TermToSearch=18081931&ordinalpos=1&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSumhttp://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&Cmd=ShowDetailView&TermToSearch=18081931&ordinalpos=1&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum


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Abstract

Dermatomyofibroma is a rare, benign cutaneous tumor derived from

myofibroblasts. It is predominantly found in young women, and only a few

cases have been reported in males. This entity is not generally well known and

often misdiagnosed. We report such a case of dermatofibroma occurring in a

23-year-old male with a brief review of the English literature.

Zenggang Pan, Edward D. Adickes, Deba P. Sarma: Dermatomyofibroma: A CaseReport And Review Of The Literature. The Internet Journal of Dermatology. 2008.

Volume 6 Number 2.

SMA

Ref.

s racMycobacterium mucogenicum is a recently characterized organism that rarely may cause human infections


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Mycobacterium mucogenicum is a recently characterized organism that rarely may cause human infections.

This rapidly growing mycobacterium is commonly identified in tap water. Both immunosuppressed and

immunocompetent patients may develop infections from Mycobacterium mucogenicum. Some patients have

experienced lethal disease, including sepsis. Infections occurring in the skin and soft tissues have been

described only after a preceding injury. We present the first case of infection with Mycobacterium

mucogenicum occurring in a patient on the TNF- antagonist etanercept and without any prior soft tissue

injury.

AFB stain

Ref.

Shehan JM, Sarma DP. (2008). Mycobacteriunmucogenicum

: Report of a skin infection associated with the use ofEtanercept. Dermatology Online J. 14(1): 5. PMID: 18319022 [PubMed - indexed for

MEDLINE]

Abstract
http://dermatology.cdlib.org/141/case_reports/mycobacterium/shehan.htmlhttp://dermatology.cdlib.org/141/case_reports/mycobacterium/shehan.htmlhttp://dermatology.cdlib.org/141/case_reports/mycobacterium/shehan.htmlhttp://dermatology.cdlib.org/141/case_reports/mycobacterium/shehan.htmlhttp://dermatology.cdlib.org/141/case_reports/mycobacterium/shehan.htmlhttp://dermatology.cdlib.org/141/case_reports/mycobacterium/4.jpghttp://dermatology.cdlib.org/141/case_reports/mycobacterium/3.jpghttp://dermatology.cdlib.org/141/case_reports/mycobacterium/2.jpghttp://dermatology.cdlib.org/141/case_reports/mycobacterium/1.jpghttp://dermatology.cdlib.org/141/case_reports/mycobacterium/shehan.htmlhttp://dermatology.cdlib.org/141/case_reports/mycobacterium/shehan.htmlhttp://dermatology.cdlib.org/141/case_reports/mycobacterium/shehan.htmlhttp://dermatology.cdlib.org/141/case_reports/mycobacterium/shehan.htmlhttp://dermatology.cdlib.org/141/case_reports/mycobacterium/shehan.html


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Sarma DP, Wang JF, McAllister MV, Wang B, Shehan JM. (2008)

Possible implantation carcinoma of the scalp following craniotomy for metastatic renal

PMID: 18713600 [PubMed - indexed for MEDLINE

Ref.

We report a case of a 50-year-old man who developed a possible implantation

carcinoma of the scalp within the craniotomy scar 19 months after a metastatic renal

cell tumor nodule was removed from the brain. The English literature on the

implantation carcinoma is briefly reviewed.

RCC immunostain

AbstractA 58-year-old Caucasian woman presented with a cystic lump behind the
http://dermatology.cdlib.org/146/letter/implantation_carcinoma/sarma.htmlhttp://dermatology.cdlib.org/146/letter/implantation_carcinoma/3.jpghttp://dermatology.cdlib.org/146/letter/implantation_carcinoma/2.jpghttp://dermatology.cdlib.org/146/letter/implantation_carcinoma/1.jpghttp://dermatology.cdlib.org/146/letter/implantation_carcinoma/sarma.html


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Pan Z, Albertson D, Bhuller A, Wang B, Shehan JM,

Sarma DP. (2008)Angiosarcoma

of the scalp mimicking a sebaceous cyst.Dermatolgy

Online J 14 (6): 13. PMID: 18713594 [PubMed - indexedfor MEDLINE

Ref.

A 58 year old Caucasian woman presented with a cystic lump behind theright ear that was clinically diagnosed as an infected sebaceous cyst. Thelesion was treated with incision and drainage followed by antibiotics for 3months. Because there was no resolution, a biopsy was performed thatrevealed a high grade angiosarcoma. She expired 2 months later.Cutaneous angiosarcoma is an extremely aggressive tumor. Thereforeearly diagnosis and management is crucial in providing better patientcare.

CD34

Factor VIII
http://dermatology.cdlib.org/146/case_presentation/angiosarcoma/wang.htmlhttp://dermatology.cdlib.org/146/case_presentation/angiosarcoma/wang.htmlhttp://dermatology.cdlib.org/146/case_presentation/angiosarcoma/wang.htmlhttp://dermatology.cdlib.org/146/case_presentation/angiosarcoma/wang.htmlhttp://dermatology.cdlib.org/146/case_presentation/angiosarcoma/3b.jpghttp://dermatology.cdlib.org/146/case_presentation/angiosarcoma/3b.jpghttp://dermatology.cdlib.org/146/case_presentation/angiosarcoma/3a.jpghttp://dermatology.cdlib.org/146/case_presentation/angiosarcoma/2b.jpghttp://dermatology.cdlib.org/146/case_presentation/angiosarcoma/2a.jpghttp://dermatology.cdlib.org/146/case_presentation/angiosarcoma/1.jpghttp://dermatology.cdlib.org/146/case_presentation/angiosarcoma/wang.htmlhttp://dermatology.cdlib.org/146/case_presentation/angiosarcoma/wang.htmlhttp://dermatology.cdlib.org/146/case_presentation/angiosarcoma/wang.htmlhttp://dermatology.cdlib.org/146/case_presentation/angiosarcoma/wang.html


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Wang JF, Wang W, Shehan JM, Sarma DP. (2008).

Acantholyticseborrheickeratosis. The Internet JDermatol6 (2).

Indexed by Google Scholar.

Ref.

Abstract

We are reporting a rare case of an acantholytic seborrheic keratosis and briefly

reviewing the relevant literature.

AbstractWe are reporting a case of CD34 positive fibroma of the lip English literature is briefly
http://www.ispub.com/ostia/index.php?xmlFilePath=journals/ijd/vol6n2/keratosis.xmlhttp://www.ispub.com/ostia/index.php?xmlFilePath=journals/ijd/vol6n2/keratosis.xmlhttp://www.ispub.com/ostia/index.php?xmlFilePath=journals/ijd/vol6n2/keratosis.xmlhttp://www.ispub.com/ostia/index.php?xmlFilePath=journals/ijd/vol6n2/keratosis.xmlhttp://www.ispub.com/ostia/index.php?xmlFilePath=journals/ijd/vol6n2/keratosis.xmlhttp://www.ispub.com/ostia/index.php?xmlFilePath=journals/ijd/vol6n2/keratosis.xmlhttp://www.ispub.com/ostia/index.php?xmlFilePath=journals/ijd/vol6n2/keratosis.xmlhttp://www.ispub.com/ostia/index.php?xmlFilePath=journals/ijd/vol6n2/keratosis.xmlhttp://www.ispub.com/ostia/index.php?xmlFilePath=journals/ijd/vol6n2/keratosis.xmlhttp://www.ispub.com/ostia/index.php?xmlFilePath=journals/ijd/vol6n2/keratosis.xmlhttp://www.ispub.com/ostia/index.php?xmlFilePath=journals/ijd/vol6n2/keratosis.xml


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Wang JF, Sarma DP. (2008). CD34-positive

fibromaof the lip. The Internet JDermatol

6 (2). Indexed by Google Scholar.

Ref.

We are reporting a case of CD34-positive fibroma of the lip. English literature is brieflyreviewed.

A 56-year-old female presented with a slightly raised nodule on the lower lip measuring 0.7 x 0.7 cm. This lesion was noted by

the patient for about a month. There was no history of trauma or previous biopsy at this site. An excisional biopsy was performed.

Case Report

CD34 Vimentin

Abstract
http://www.ispub.com/ostia/index.php?xmlFilePath=journals/ijd/vol6n2/lip.xmlhttp://www.ispub.com/ostia/index.php?xmlFilePath=journals/ijd/vol6n2/lip.xmlhttp://www.ispub.com/ostia/index.php?xmlFilePath=journals/ijd/vol6n2/lip.xmlhttp://www.ispub.com/ostia/index.php?xmlFilePath=journals/ijd/vol6n2/lip.xmlhttp://www.ispub.com/ostia/index.php?xmlFilePath=journals/ijd/vol6n2/lip.xmlhttp://www.ispub.com/ostia/index.php?xmlFilePath=journals/ijd/vol6n2/lip.xmlhttp://www.ispub.com/ostia/index.php?xmlFilePath=journals/ijd/vol6n2/lip.xmlhttp://www.ispub.com/ostia/index.php?xmlFilePath=journals/ijd/vol6n2/lip.xmlhttp://www.ispub.com/ostia/index.php?xmlFilePath=journals/ijd/vol6n2/lip.xmlhttp://www.ispub.com/ostia/index.php?xmlFilePath=journals/ijd/vol6n2/lip.xml


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Wang JF, Wang B, Shehan JM, Sarma DP. (2008). Use of MITF (

Microphthalmia-Associated Transcription Factor)immunostain

for diagnosis ofdesmoplasticmelanoma. The Internet JDermatol6 (2).

Indexed by Google Scholar.

Ref.

We are reporting a case of desmoplastic malignant melanoma that was confirmed by

immunostaining for microphthalmia-associated transcription factor (MITF). A brief review

of utility of MITF for diagnosis of melanoma is presented.

S100 MITF

Abstract
http://www.ispub.com/ostia/index.php?xmlFilePath=journals/ijd/vol6n2/mitf.xmlhttp://www.ispub.com/ostia/index.php?xmlFilePath=journals/ijd/vol6n2/mitf.xmlhttp://www.ispub.com/ostia/index.php?xmlFilePath=journals/ijd/vol6n2/mitf.xmlhttp://www.ispub.com/ostia/index.php?xmlFilePath=journals/ijd/vol6n2/mitf.xmlhttp://www.ispub.com/ostia/index.php?xmlFilePath=journals/ijd/vol6n2/mitf.xmlhttp://www.ispub.com/ostia/index.php?xmlFilePath=journals/ijd/vol6n2/mitf.xmlhttp://www.ispub.com/ostia/index.php?xmlFilePath=journals/ijd/vol6n2/mitf.xmlhttp://www.ispub.com/ostia/index.php?xmlFilePath=journals/ijd/vol6n2/mitf.xmlhttp://www.ispub.com/ostia/index.php?xmlFilePath=journals/ijd/vol6n2/mitf.xmlhttp://www.ispub.com/ostia/index.php?xmlFilePath=journals/ijd/vol6n2/mitf.xmlhttp://www.ispub.com/ostia/index.php?xmlFilePath=journals/ijd/vol6n2/mitf.xmlhttp://www.ispub.com/ostia/index.php?xmlFilePath=journals/ijd/vol6n2/mitf.xmlhttp://www.ispub.com/ostia/index.php?xmlFilePath=journals/ijd/vol6n2/mitf.xmlhttp://www.ispub.com/ostia/index.php?xmlFilePath=journals/ijd/vol6n2/mitf.xmlhttp://www.ispub.com/ostia/index.php?xmlFilePath=journals/ijd/vol6n2/mitf.xmlhttp://www.ispub.com/ostia/index.php?xmlFilePath=journals/ijd/vol6n2/mitf.xmlhttp://www.ispub.com/ostia/index.php?xmlFilePath=journals/ijd/vol6n2/mitf.xml


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Wang B, Sarma DP, Javadzadeh BM, Shehan JM, (2008).

Solid and cystic clear cellhidradenomawith focalintracysticcarcinoma in-situ. The Internet JDermatol6(2). Indexed by Google Scholar.

Ref.

A rare case of a nodulocystic hidradenoma with intracystic carcinoma in-situ occurring

in the scalp of a 79-year-old man is reported.

Abstract
http://www.ispub.com/ostia/index.php?xmlFilePath=journals/ijd/vol6n2/solid.xmlhttp://www.ispub.com/ostia/index.php?xmlFilePath=journals/ijd/vol6n2/solid.xmlhttp://www.ispub.com/ostia/index.php?xmlFilePath=journals/ijd/vol6n2/solid.xmlhttp://www.ispub.com/ostia/index.php?xmlFilePath=journals/ijd/vol6n2/solid.xmlhttp://www.ispub.com/ostia/index.php?xmlFilePath=journals/ijd/vol6n2/solid.xmlhttp://www.ispub.com/ostia/index.php?xmlFilePath=journals/ijd/vol6n2/solid.xmlhttp://www.ispub.com/ostia/index.php?xmlFilePath=journals/ijd/vol6n2/solid.xmlhttp://www.ispub.com/ostia/index.php?xmlFilePath=journals/ijd/vol6n2/solid.xmlhttp://www.ispub.com/ostia/index.php?xmlFilePath=journals/ijd/vol6n2/solid.xmlhttp://www.ispub.com/ostia/index.php?xmlFilePath=journals/ijd/vol6n2/solid.xmlhttp://www.ispub.com/ostia/index.php?xmlFilePath=journals/ijd/vol6n2/solid.xmlhttp://www.ispub.com/ostia/index.php?xmlFilePath=journals/ijd/vol6n2/solid.xmlhttp://www.ispub.com/ostia/index.php?xmlFilePath=journals/ijd/vol6n2/solid.xmlhttp://www.ispub.com/ostia/index.php?xmlFilePath=journals/ijd/vol6n2/solid.xml


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Sarma DP, Teruya B, Wang B (2008). Paraganglioma-like dermalmelanocytic

tumor: a case report. Cases Journal 1:48. PMID: 18638402 [PubMed - in process]

Ref.

Abstract

Paraganglioma-like dermal melanocytic tumor is a rare subtype of benign dermal melanocytic tumors. Its

histopathologic features resemble those of paraganglioma, but the immunostaining characteristics are

those of melanocytic lesions.

We report a case of a 60-year-old male with a paraganglioma-like dermal melanocytic tumor of his left

cheek and briefly review the English literature.

S100

AbstractWe are reporting two cases of glomus tumor of the cheek that we had recently
http://www.casesjournal.com/content/1/1/48http://www.casesjournal.com/content/1/1/48http://www.casesjournal.com/content/1/1/48http://www.casesjournal.com/content/1/1/48/figure/F3http://www.casesjournal.com/content/1/1/48/figure/F2http://www.casesjournal.com/content/1/1/48/figure/F1http://www.casesjournal.com/content/1/1/48http://www.casesjournal.com/content/1/1/48http://www.casesjournal.com/content/1/1/48http://www.casesjournal.com/content/1/1/48


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Wang B, Wang J, Shehan J, Sarma DP.(2008). Glomus

tumor of the cheek. The Internet J of Dermatology 6 (2). Indexed by GoogleScholar.

Ref.

We are reporting two cases of glomus tumor of the cheek that we had recentlyencountered during the last six months. English literature is briefly reviewed.

Case ReportsA 51-year-old male presented with an asymptomatic red right lower cheek lesion that was clinically diagnosed as

a venous lake.

AbstractFibroepithelioma of Pinkus (FEP) is a rare indolent variety of basal cell carcinoma that is typically polypoid and
http://www.ispub.com/ostia/index.php?xmlFilePath=journals/ijd/vol6n2/glomus.xmlhttp://www.ispub.com/ostia/index.php?xmlFilePath=journals/ijd/vol6n2/glomus.xmlhttp://www.ispub.com/ostia/index.php?xmlFilePath=journals/ijd/vol6n2/glomus.xmlhttp://www.ispub.com/ostia/index.php?xmlFilePath=journals/ijd/vol6n2/glomus.xml


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Pan Z, Huynh N, Sarma DP. (2008). FibroepitheliomaofPinkus

in a 9-year-old boy: a case report. Cases Journal 1:21. PMID: 18588684 [PubMed -in process]

Ref.

Fibroepithelioma of Pinkus (FEP) is a rare indolent variety of basal cell carcinoma that is typically polypoid and

located on the trunk of adult males aged 4060 years. Basal cell carcinoma (including FEP) is very rare in the

pediatric population. We are reporting such a case occurring in a 9-year-old boy.

Case presentation

A 9-year-old boy presented with a 6.0-mm polypoid erythematous nodule with ulceration on his left chest. An

excisional biopsy was done. Histologically, the tumor revealed several foci of superficial basal cell carcinoma along

the epidermis. In the dermis, the tumor was composed of basaloid epithelial anastomosing cords that wereseparated by fibrovascular stroma connected to the overlying epidermis (Figure 1). The histopathological features

were that of a fibroepithelioma of Pinkus. The lesion was completely removed with clear biopsy margin. The patient

is being followed for any possible local recurrence.
http://www.casesjournal.com/content/1/1/21http://www.casesjournal.com/content/1/1/21http://www.casesjournal.com/content/1/1/21http://www.casesjournal.com/content/1/1/21http://www.casesjournal.com/content/1/1/21/figure/F1http://www.casesjournal.com/content/1/1/21/figure/F1?highres=yhttp://www.casesjournal.com/content/1/1/21/figure/F1http://www.casesjournal.com/content/1/1/21http://www.casesjournal.com/content/1/1/21http://www.casesjournal.com/content/1/1/21http://www.casesjournal.com/content/1/1/21


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Shehan J, Wang JF, Repertinger S, Sarma DP.(2008). Perianal

squamous cell carcinoma in-situ: a report of two humanpapillomavirus-negative cases. Cases J 1(1):114. PMID: 18715505 [PubMed - in process]

Ref.

AbstractWe are reporting two cases of perianal squamous cell carcinoma in-situ, negative for high-risk (HR) and

low-risk (LR) human papilloma viruses. A brief review of anal and perianal squamous cell carcinoma and

the role of HPV are presented.

Introduction

Squamous cell carcinoma, the second most common form of skin cancer, most often affects sun-exposedsurfaces. However, squamous cell carcinoma can involve skin surfaces not previously exposed to sunlight,

such as in the anal and perianal regions. Invasive perianal squamous cell carcinoma is a locally infiltrative

malignant skin tumor that exhibits destructive growth. It is a relatively uncommon tumor, which develops

from the precursor lesion anal intraepithelial neoplasia (AIN). Immunosuppression is felt to be a risk factor.

An-86-year-old male with a history of multiple actinic keratoses and seborrheic
http://www.ncbi.nlm.nih.gov/pubmed/18715505?dopt=AbstractPlus&holding=f1000,f1000m,isrctnhttp://www.ncbi.nlm.nih.gov/pubmed/18715505?dopt=AbstractPlus&holding=f1000,f1000m,isrctnhttp://www.ncbi.nlm.nih.gov/pubmed/18715505?dopt=AbstractPlus&holding=f1000,f1000m,isrctnhttp://www.ncbi.nlm.nih.gov/pubmed/18715505?dopt=AbstractPlus&holding=f1000,f1000m,isrctnhttp://www.casesjournal.com/content/1/1/114/figure/F3?highres=yhttp://www.casesjournal.com/content/1/1/114/figure/F2?highres=yhttp://www.casesjournal.com/content/1/1/114/figure/F1?highres=yhttp://www.ncbi.nlm.nih.gov/pubmed/18715505?dopt=AbstractPlus&holding=f1000,f1000m,isrctnhttp://www.ncbi.nlm.nih.gov/pubmed/18715505?dopt=AbstractPlus&holding=f1000,f1000m,isrctnhttp://www.ncbi.nlm.nih.gov/pubmed/18715505?dopt=AbstractPlus&holding=f1000,f1000m,isrctnhttp://www.ncbi.nlm.nih.gov/pubmed/18715505?dopt=AbstractPlus&holding=f1000,f1000m,isrctn


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Repertinger S, Wang J, Adickes E, Sarma DP. (2008).

Melanoma in-situ arising inseborrheickeratosis: a case report. Cases J 1 (1):263. PMID: 18947402 [PubMed - in process]

Ref.

An-86-year-old male with a history of multiple actinic keratoses and seborrheic

keratoses of the head and trunk presented with a mid-back skin lesion. The lesion

was poorly circumscribed, flat, and gray, with a pink-tan, well-circumscribed scaly

nodule within it. The biopsied lesion was composed of the usual features of

hyperkeratotic seborrheic keratosis, but with focal atypical melanocytic proliferation

with nesting along the dermal-epidermal junction. We interpreted this lesion as amelanoma in-situ arising within a seborrheic keratosis.

MITF

Abstract

Fibroepithelioma of Pinkus is a rare indolent variant of basal cell carcinoma (BCC) The presence of pleomorphic
http://www.casesjournal.com/content/1/1/263http://www.casesjournal.com/content/1/1/263http://www.casesjournal.com/content/1/1/263http://www.casesjournal.com/content/1/1/263http://www.casesjournal.com/content/1/1/263http://www.casesjournal.com/content/1/1/263/figure/F3?highres=yhttp://www.casesjournal.com/content/1/1/263/figure/F2?highres=yhttp://www.casesjournal.com/content/1/1/263/figure/F1?highres=yhttp://www.casesjournal.com/content/1/1/263http://www.casesjournal.com/content/1/1/263http://www.casesjournal.com/content/1/1/263http://www.casesjournal.com/content/1/1/263


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Repertinger SK, Stevens T, Markin N, Klepacz H, Sarma DP.(2008).

Fibroepithelioma of Pinkus with pleomorphic epithelial giant cells. Dermatology OnlineJ 14(12):13. {Pubmed- in process].

Ref.

Fibroepithelioma of Pinkus is a rare, indolent variant of basal cell carcinoma (BCC). The presence of pleomorphic

giant cells in such a tumor is extremely rare and to our knowledge, only one such case has been previously

reported in the literature. We report another case occurring as a pedunculated, gluteal lesion in an 82-year-old

man. The nodule was lightly pigmented, polypoid, and measured 1.0 cm in greatest dimension.

Immunohistochemical staining confirmed that the giant cells were of epithelial origin and that the proliferative rate

of these cells was low

CD68

p63

Abstract
http://dermatology-s10.cdlib.org/1412/case_presentations/pinkus/5.jpghttp://dermatology-s10.cdlib.org/1412/case_presentations/pinkus/4.jpghttp://dermatology-s10.cdlib.org/1412/case_presentations/pinkus/3.jpghttp://dermatology-s10.cdlib.org/1412/case_presentations/pinkus/2.jpghttp://dermatology-s10.cdlib.org/1412/case_presentations/pinkus/1.jpg


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Liu H, Wang J, Bewtra C, Sarma DP. (2009).

Symptomatic gallbladder metastasis from cutaneous melanoma. The Internet JGastroenterol7(2). Indexed by Google Scholar

Ref.

Although 50%-65% of metastatic gallbladder tumors come form malignant

melanoma, clinically diagnosed cases are very rare. We are reporting such a

symptomatic case of metastatic melanoma in the gall bladder occurring in a 40-year-

old man.

Figure 1: Microscopic picture of metastatic melanoma in the gallbladder, H&E,X20

Capillary hemangiomas are very common benign vascular neoplasms which frequently occur in the skinCapillary hemangiomas are very common benign vascular neoplasms which frequently occur in the skin
http://www.ispub.com/ostia/index.php?xmlFilePath=journals/ijge/vol7n2/melanoma.xmlhttp://www.ispub.com/ostia/index.php?xmlFilePath=journals/ijge/vol7n2/melanoma.xmlhttp://www.ispub.com/ostia/index.php?xmlFilePath=journals/ijge/vol7n2/melanoma.xmlhttp://www.ispub.com/ostia/index.php?xmlFilePath=journals/ijge/vol7n2/melanoma.xmlhttp://www.ispub.com/ostia/index.php?xmlFilePath=journals/ijge/vol7n2/melanoma.xmlhttp://www.ispub.com/ostia/index.php?xmlFilePath=journals/ijge/vol7n2/melanoma.xmlhttp://www.ispub.com/ostia/index.php?xmlFilePath=journals/ijge/vol7n2/melanoma.xml


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p y g y g p q yp y g y g p q y

and intraoral mucous membranes. The intravascular variant of this lesion, however, is distinctlyand intraoral mucous membranes. The intravascular variant of this lesion, however, is distinctly

uncommon and has been reported rarely in the English literature. Those reported cases describe thisuncommon and has been reported rarely in the English literature. Those reported cases describe this

tumor as arising in veins in cutaneous and extracutaneous sites. Here we report two cases oftumor as arising in veins in cutaneous and extracutaneous sites. Here we report two cases of

intravascular capillary hemangioma arising in the skin.intravascular capillary hemangioma arising in the skin.

An excisional biopsy of a painless subcutaneous nodule that had been present for anunknown period of time in the right forearm of a 44-year-old woman was submitted.

Ref:

S. K. Repertinger, E. E. Santos, M. Chen & D. P. Sarma : Intravascular

Capillary Hemangioma of the Skin . The Internet Journal of Dermatology.2009 Volume 7 Number 1

An excisional biopsy of a skin papule was taken of the left cheek fromAn excisional biopsy of a skin papule was taken of the left cheek from
http://www.ispub.com/ispub/ijd/volume_7_number_1_18/intravascular_capillary_hemangioma_of_the_skin/hemangioma-fig2.jpghttp://www.ispub.com/ispub/ijd/volume_7_number_1_18/intravascular_capillary_hemangioma_of_the_skin/hemangioma-fig1.jpg


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An excisional biopsy of a skin papule was taken of the left cheek fromAn excisional biopsy of a skin papule was taken of the left cheek from

a 45-year-old man. The asymptomatic lesion has been present for ana 45-year-old man. The asymptomatic lesion has been present for an

unknown period of time.unknown period of time.

Ref.

D. P. Sarma & S. Repertinger : Cutaneous Mixed Tumor . The Internet Journal of

Dermatology. 2009 Volume 7 Number 1

Diagnostic microscopic images of condyloma acuminatum and scabies are presented
http://www.ispub.com/ispub/ijd/volume_7_number_1_18/cutaneous_mixed_tumor/mixed-fig2.jpghttp://www.ispub.com/ispub/ijd/volume_7_number_1_18/cutaneous_mixed_tumor/mixed-fig1.jpg


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D. P. Sarma, S. Panganiban & D. Albertson : Diagnostic Microscopic Images:

Condyloma Acuminatum and Scabies . The Internet Journal of Dermatology. 2009Volume 7 Number 1

Ref.

Diagnostic microscopic images of condyloma acuminatum and scabies are presented

with a brief discussion of the diagnostic features.

CASE 1. Biopsy of a 5-mm raised skin lesion from the vulva of a 25-year-old woman.

Low risk HPV

CASE 2. Biopsy of an extremely pruritic rash on the right hand of a 20-year-old man with similar rash

on the left foot.

Diagnosis: Condyloma acuminata

Diagnosis: Scabies

This is a photomicrograph (Figure 1) of a biopsied painless, 6-mm scrotal nodule from a

47 ld th t h b t f k i d f ti Th
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D. P. Sarma, E. E. Santos, C. E. Hagen & S. Repertinger : ScrotalLeiomyoma.

The Internet Journal of Dermatology.2009 Volume 7 Number 1

47-year-old man that has been present for an unknown period of time. There was no

history of trauma or previous surgical intervention. The epidermis is raised due to an

eosinophilic dermal soft tissue tumor. The overlying epidermis is essentially normal. The

dermal nodule is composed of bundles and fascicles of smooth muscle cells containing

red fibrillar cytoplasm and elongated nuclei with blunted ends (Figure2). There is no

cytologic atypia, increased or atypical mitosis, or necrosis.

Diagnosis: Leiomyoma

Ref.

A 46-year-old female presented with a subcutaneous nodule in her right neck. On
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Z. Pan, J. F. Wang, N. Huynh, S. Repertinger & D. P. Sarma : Vascular Spiradenoma .

The Internet Journal of Dermatology. 2009 Volume 7 Number 1

Ref.

y p g

gross examination, this well circumscribed nodular lesion measured 1.0 0.7 0.4

cm and showed a firm, gray-pink cut surface.

Diagnosis: Vascular spiradenoma

Poroma is a benign adnexal skin tumor seen in middle aged individuals with no
http://www.ispub.com/ispub/ijd/volume_7_number_1_18/vascular_spiradenoma/vascular-fig3.jpghttp://www.ispub.com/ispub/ijd/volume_7_number_1_18/vascular_spiradenoma/vascular-fig2.jpghttp://www.ispub.com/ispub/ijd/volume_7_number_1_18/vascular_spiradenoma/vascular-fig1.jpg


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g g

sex predilection. The acral sites are the most commonly affected regions. Hip or

buttock as a location of origin has rarely been reported. We report two cases of

poroma, one located on the hip of a 75-year-old man and the other on the

buttock of a 60-year-old man.

Ref:

Sarma DP, Zaman SU, Santos EE, Shehan JM. (2009). Poroma

of the hip and buttock. Dermatology Online J 15(5):10. PMID: 19624988 [Pubmed-

indexed for MEDLINE].

A 55-year-old obese woman presented with a 4-month history of hemorrhagic

discharge from the umbilicus Deep from the base of the umbilicus a 0 8 cm gray tan
http://dermatology-s10.cdlib.org/1505/case_presentations/poroma/shehan.htmlhttp://dermatology-s10.cdlib.org/1505/case_presentations/poroma/shehan.htmlhttp://dermatology-s10.cdlib.org/1505/case_presentations/poroma/5.jpghttp://dermatology-s10.cdlib.org/1505/case_presentations/poroma/4.jpghttp://dermatology-s10.cdlib.org/1505/case_presentations/poroma/3.jpghttp://dermatology-s10.cdlib.org/1505/case_presentations/poroma/2.jpghttp://dermatology-s10.cdlib.org/1505/case_presentations/poroma/1.jpghttp://dermatology-s10.cdlib.org/1505/case_presentations/poroma/shehan.htmlhttp://dermatology-s10.cdlib.org/1505/case_presentations/poroma/shehan.html


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discharge from the umbilicus. Deep from the base of the umbilicus, a 0.8 cm gray-tan

mass was removed that on microscopic examination revealed a lint ball.

Fig 1. Refracile lint material, keratin,

neutrophils

Fig 2. Lint under polarized light

Ref:

Sarma DP, Teruya B (2009). Lint ballomphalitis

, a rare cause of umbilical discharge in an adult woman: a case report. Cases J 2: 7

[Pubmed- indexed for MEDLINE].

Dilated Pore of Winer Dr Louis H Winer andDilated Pore of Winer Dr Louis H Winer and
http://casesjournal.com/casesjournal/article/view/7785http://casesjournal.com/casesjournal/article/view/7785http://casesjournal.com/casesjournal/article/view/7785http://casesjournal.com/casesjournal/article/view/7785http://casesjournal.com/casesjournal/article/view/7785http://casesjournal.com/casesjournal/article/view/7785


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Dilated Pore of Winer, Dr. Louis H Winer andDilated Pore of Winer, Dr. Louis H Winer and

Wine GlassWine Glass

Ref:

Sarma DP (2009). Dilated pore ofWiner,Dr.LouisHWiner

and wine glass. The Internet JDermatol7(2). Indexed by Google Scholar

Common Spindle Cell Malignant Neoplasms of the
http://www.ispub.com/journal/the_internet_journal_of_dermatology/volume_7_number_2_23/article_printable/dilated-pore-of-winer-dr-louis-h-winer-and-wine-glass.htmlhttp://www.ispub.com/journal/the_internet_journal_of_dermatology/volume_7_number_2_23/article_printable/dilated-pore-of-winer-dr-louis-h-winer-and-wine-glass.htmlhttp://www.ispub.com/journal/the_internet_journal_of_dermatology/volume_7_number_2_23/article_printable/dilated-pore-of-winer-dr-louis-h-winer-and-wine-glass.htmlhttp://www.ispub.com/journal/the_internet_journal_of_dermatology/volume_7_number_2_23/article_printable/dilated-pore-of-winer-dr-louis-h-winer-and-wine-glass.htmlhttp://www.ispub.com/journal/the_internet_journal_of_dermatology/volume_7_number_2_23/article_printable/dilated-pore-of-winer-dr-louis-h-winer-and-wine-glass.htmlhttp://www.ispub.com/journal/the_internet_journal_of_dermatology/volume_7_number_2_23/article_printable/dilated-pore-of-winer-dr-louis-h-winer-and-wine-glass.htmlhttp://www.ispub.com/journal/the_internet_journal_of_dermatology/volume_7_number_2_23/article_printable/dilated-pore-of-winer-dr-louis-h-winer-and-wine-glass.htmlhttp://www.ispub.com/journal/the_internet_journal_of_dermatology/volume_7_number_2_23/article_printable/dilated-pore-of-winer-dr-louis-h-winer-and-wine-glass.htmlhttp://www.ispub.com/journal/the_internet_journal_of_dermatology/volume_7_number_2_23/article_printable/dilated-pore-of-winer-dr-louis-h-winer-and-wine-glass.htmlhttp://www.ispub.com/journal/the_internet_journal_of_dermatology/volume_7_number_2_23/article_printable/dilated-pore-of-winer-dr-louis-h-winer-and-wine-glass.htmlhttp://www.ispub.com/journal/the_internet_journal_of_dermatology/volume_7_number_2_23/article_printable/dilated-pore-of-winer-dr-louis-h-winer-and-wine-glass.htmlhttp://www.ispub.com/journal/the_internet_journal_of_dermatology/volume_7_number_2_23/article_printable/dilated-pore-of-winer-dr-louis-h-winer-and-wine-glass.htmlhttp://www.ispub.com/journal/the_internet_journal_of_dermatology/volume_7_number_2_23/article_printable/dilated-pore-of-winer-dr-louis-h-winer-and-wine-glass.htmlhttp://www.ispub.com/journal/the_internet_journal_of_dermatology/volume_7_number_2_23/article_printable/dilated-pore-of-winer-dr-louis-h-winer-and-wine-glass.htmlhttp://www.ispub.com/journal/the_internet_journal_of_dermatology/volume_7_number_2_23/article_printable/dilated-pore-of-winer-dr-louis-h-winer-and-wine-glass.htmlhttp://www.ispub.com/journal/the_internet_journal_of_dermatology/volume_7_number_2_23/article_printable/dilated-pore-of-winer-dr-louis-h-winer-and-wine-glass.htmlhttp://www.ispub.com/journal/the_internet_journal_of_dermatology/volume_7_number_2_23/article_printable/dilated-pore-of-winer-dr-louis-h-winer-and-wine-glass.html


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Ref;

Repertinger S, Teruya B, Sarma DP (2009).Common spindle cell malignant

neoplasms

of the skin: Differential diagnosis and review of the literature. The Internet J

Dermatol7(2). Indexed by Google Scholar.

Skin: Differential Diagnosis and Review of the

Literature

Malignant and borderline-malignant neoplasms of the dermis can

pose diagnostic challenges. Because these tumors can share similar

clinical and histologic features, including a predominantly spindle cell

morphology, the pathologist must be familiar with these entities in

order to facilitate accurate diagnosis, as treatment for these tumors

may be different. We review several of these lesions with respect to

clinical and histologic features: desmoplastic melanoma, spindle cell

carcinoma, spindle cell atypical fibroxanthoma, dermatofibrosarcoma

protuberans, and cutaneous leiomyosarcoma.

A 37-year-old woman presented with a 5 mm, smooth papule of the chin. The lesion
http://www.ispub.com/journal/the_internet_journal_of_dermatology/volume_7_number_2_23/article_printable/common-spindle-cell-malignant-neoplasms-of-the-skin-differential-diagnosis-and-review-of-the-literature.htmlhttp://www.ispub.com/journal/the_internet_journal_of_dermatology/volume_7_number_2_23/article_printable/common-spindle-cell-malignant-neoplasms-of-the-skin-differential-diagnosis-and-review-of-the-literature.htmlhttp://www.ispub.com/journal/the_internet_journal_of_dermatology/volume_7_number_2_23/article_printable/common-spindle-cell-malignant-neoplasms-of-the-skin-differential-diagnosis-and-review-of-the-literature.htmlhttp://www.ispub.com/journal/the_internet_journal_of_dermatology/volume_7_number_2_23/article_printable/common-spindle-cell-malignant-neoplasms-of-the-skin-differential-diagnosis-and-review-of-the-literature.htmlhttp://www.ispub.com/journal/the_internet_journal_of_dermatology/volume_7_number_2_23/article_printable/common-spindle-cell-malignant-neoplasms-of-the-skin-differential-diagnosis-and-review-of-the-literature.htmlhttp://www.ispub.com/journal/the_internet_journal_of_dermatology/volume_7_number_2_23/article_printable/common-spindle-cell-malignant-neoplasms-of-the-skin-differential-diagnosis-and-review-of-the-literature.htmlhttp://www.ispub.com/journal/the_internet_journal_of_dermatology/volume_7_number_2_23/article_printable/common-spindle-cell-malignant-neoplasms-of-the-skin-differential-diagnosis-and-review-of-the-literature.htmlhttp://www.ispub.com/journal/the_internet_journal_of_dermatology/volume_7_number_2_23/article_printable/common-spindle-cell-malignant-neoplasms-of-the-skin-differential-diagnosis-and-review-of-the-literature.htmlhttp://www.ispub.com/journal/the_internet_journal_of_dermatology/volume_7_number_2_23/article_printable/common-spindle-cell-malignant-neoplasms-of-the-skin-differential-diagnosis-and-review-of-the-literature.htmlhttp://www.ispub.com/journal/the_internet_journal_of_dermatology/volume_7_number_2_23/article_printable/common-spindle-cell-malignant-neoplasms-of-the-skin-differential-diagnosis-and-review-of-the-literature.html


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Ref:

Repertinger S, Sarma DP (2009).

Palisaded encapsulated neuroma (PEN). The Internet JDermatol7(2). Indexed by Google Scholar

y p , p p

was present for an unknown duration.

S-100: Positive EMA: Capsule is positive

Desmoplastic trichilemmoma is a rare trichilemmoma variant arising from
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Ref:

Sarma DP, Santos EE (2009). Desmoplastictrichilemmoma. The Internet JDermatol7(2). Indexed by Google Scholar.

the outer root sheath or infundibular epithelium and occurring

predominately on the face of affected individuals. The patient commonly

presents with a slow-growing, solitary, dome-shaped papule. Simple

excision of the lesion is the treatment of choice and is curative.

A 44-year-old woman presented with a 5-mm smooth flesh-colored papule of
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Ref:

Sarma DP, Repertinger SK (2009).

Epithelioid cell histiocytoma: a case report and brief review of the literature, with an e

A 44-year-old woman presented with a 5-mm, smooth, flesh-colored papule of

the cheek. The lesion had been present for an unknown duration.

Microscopically (Figures 1 and 2), the epidermis was unremarkable. The upper

dermal tumor was composed of large epitheliod cells containing bland nuclei

with occasional large nucleoli. There were no mitotic figures or necrosis. There

were a few multinucleated giant cells but no foam cell. The tumor cells were

strongly positive for Vimentin (Figure 3) and focally positive for CD68 (Figure 4)

and were negative for CK AE1/3, S-100, MITF, SMA, Myogenin, and CD34

CD 68

A brief review of the variations ofmicroscopic appearances of
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Ref:

Sarma DP, Repertinger S (2009). Seborrheickeratosis

: A pictorial review ofthehistologicvariations. The Internet JDermatol


microscopic appearances of

seborrheic keratosis is presented.

A 31-year-old woman underwent an excision of a ruptured epidermal cyst of the leftaxilla One month later the previous excision site was re-excised secondary to a non-
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axilla. One month later, the previous excision site was re excised secondary to a non

healing, inflamed papule in order to exclude recurrent epidermal cyst formation.

Microscopic examination revealed that the cause of the papular lesion was acquired

trichostasis, rather than a recurrent epidermal cyst. Conclusion A papular or nodular

lesion at a postoperative site may rarely be caused by acquired trichostasis and should

be considered as one of the differential diagnosis.

Ref:

Sarma DP, Maertins BA, Santos EE (2009).Acquiredtrichostasisin postoperative site: a case report. Cases J 2: 9310.[Pubmed-indexed for MEDLINE].

w a pa n ess . cm su areo ar no u e o e n pp e presen orseveral months. A biopsy revealed an infiltrating adnexal neoplasm withf i il h i i l i i h f
http://www.casesjournal.com/content/2/1/9310http://www.casesjournal.com/content/2/1/9310http://www.casesjournal.com/content/2/1/9310http://www.casesjournal.com/content/2/1/9310http://www.casesjournal.com/content/2/1/9310http://www.casesjournal.com/content/2/1/9310


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features similar to those seen in syringomas commonly occurring in the faceand pubis. The infiltrating syringomatous adenoma of the nipple occursalmost exclusively in women of all ages and is cured by simple excision.Microscopic appearance this rare benign infiltrating neoplasm of eccrine duct

origin occurring in woman's breast should not be misinterpreted as morecommon infiltrating primary breast carcinoma.

Sarma DP, Stevens T (2009).Infiltrating syringomatous adenoma of the nipple: a case report Cases J 2:
http://www.ncbi.nlm.nih.gov/pubmed/20062695?itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum&ordinalpos=1http://www.ncbi.nlm.nih.gov/pubmed/20062695?itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum&ordinalpos=1

cumc dermatopathology publications 2006-2009

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