course plan sixth - devi ahilya vishwavidyalaya plan_sixth.pdf · detailed course plan ......

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1 School of Pharmacy Devi Ahilya Vishwavidyalaya, Indore DETAILED COURSE PLAN A. Subject Specification [1] Subject title and code: Pharmaceutics-VIII (Pharmaceutical Technology-II) 601 T [1]. Program(s) in which the Subject is offered: B. Pharm (If general elective available in many programs indicate this rather than list programs) [2]. Name of faculty member responsible for the Subject : Dr.Masheer Ahmed Khan [3]. Level/year at which this Subject is offered : VI Semester B. Objectives [1]. Objective of the Subject: The objective is to understand the pharmaceutical technology with respect to formulation of different dosage forms including microencapsulation, parenterals, controlled release systems, novel drug delivery and ophthalmic preparations. C. Subject Description [1]. Subject Detail S. No. Topic No. of Classes 01 Microencapsulation: Types of microcapsules, importance of microencapsulation in pharmacy, microencapsulation by phase separation, co-accervation, multiorifice centrifugal, spray drying, spray congealing, polymerization complex emulsion, air suspension technique, coating pan and other techniques, evaluation of microcapsules 10 02 Parenteral products: a. Preformulation factors, routes of administration, water for injection, pyrogenicity, non-aqueous vehicles, and isotonicity. b. Aseptic techniques: Sources of contamination and methods of prevention, design of aseptic area, laminar flow bench services and maintenance. c. Formulation details, containers and closures and their selection. d. Pre-filling treatment, washing of containers and closures, preparation of solution and suspensions, filling and closing of ampoules, vials, infusion fluids, lyophilization and preparation of sterile powders, equipments for large-scale manufacture and evaluation of parenteral products. 10

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Page 1: course plan sixth - Devi Ahilya Vishwavidyalaya plan_sixth.pdf · DETAILED COURSE PLAN ... streptokinase and steptodornase, amylase and protease, ... //enzyme+immobilization+ppt

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School of Pharmacy Devi Ahilya Vishwavidyalaya, Indore

DETAILED COURSE PLAN

A. Subject Specification

[1] Subject title and code: Pharmaceutics-VIII (Pharmaceutical Technology-II) 601 T

[1]. Program(s) in which the Subject is offered: B. Pharm (If general elective available in many programs indicate this rather than list programs)

[2]. Name of faculty member responsible for the Subject : Dr.Masheer Ahmed Khan [3]. Level/year at which this Subject is offered : VI Semester

B. Objectives

[1]. Objective of the Subject: The objective is to understand the pharmaceutical technology with respect to formulation

of different dosage forms including microencapsulation, parenterals, controlled release systems, novel drug delivery and ophthalmic preparations.

C. Subject Description [1]. Subject Detail S. No. Topic No. of Classes

01 Microencapsulation: Types of microcapsules, importance of microencapsulation in pharmacy, microencapsulation by phase separation, co-accervation, multiorifice centrifugal, spray drying, spray congealing, polymerization complex emulsion, air suspension technique, coating pan and other techniques, evaluation of microcapsules

10

02 Parenteral products: a. Preformulation factors, routes of administration, water for injection, pyrogenicity, non-aqueous vehicles, and isotonicity. b. Aseptic techniques: Sources of contamination and methods of prevention, design of aseptic area, laminar flow bench services and maintenance. c. Formulation details, containers and closures and their selection. d. Pre-filling treatment, washing of containers and closures, preparation of solution and suspensions, filling and closing of ampoules, vials, infusion fluids, lyophilization and preparation of sterile powders, equipments for large-scale manufacture and evaluation of parenteral products.

10

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03 Design, development, production and evaluation of controlled released formulations.

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04 Novel drug delivery systems: Drawbacks and deficiencies of conventional drug delivery systems, introduction to novel drug delivery systems, e.g., transdermal drug delivery patches, ocular inserts and osmotic pumps, introduction of liposomes and prodrugs.

09

05 Ophthalmic preparations: Requirements, formulation and methods of preparations, containers, and evaluation.

05

Total No. of Classes 40

[2]. Subject Components (total contact hours):

Lecture: 4 hrs. Per week Practical: 6 hrs. Per week Other: -

[3]. Development of Learning Outcomes in Domains of Learning

i. Description of the knowledge to be acquired: Study of all methods involved in microencapsulation. Study of formulation considerations in preparing Parenterals. Design, development, and evaluation of controlled released formulations.

Study of Novel drug delivery systems. Study of Ophthalmic preparations.

ii. Teaching strategies to be used to develop that knowledge: Black board teaching, Power point presentation, Overhead projector, Group discussion, Assignments.

D. Learning Resources

i. Essential References, Required Text(s), Electronic Materials, Web Sites, Other learning material such as computer-based programs/CD, professional standards/regulations: Turco, S., Sterile Dosage Form, Wiliams & Wilkins, USA. Gennaro, A.R., Remington’s The Science and practice of Pharmacy, Lippincott, Williams & Wilkins, Philadelphia. Lachman, L., Lieberman, H.A. and Kanig, J.L., The Theory and Practice of Industrial Pharmacy, Varghese Publishing House, Mumbai. Rawlins, E.A. (Ed.), Bentley’s Textbook of Pharmaceutics, Bailliere Tindall, London. Pharmacopoeia of India, Ministry of Health and Family Welfare, Govt. of India, New

Delhi. Avis, K.E., Lachman, L. and Lieberman, H.A., Pharmaceutical Dosage Forms.

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Parenteral Medication Vol. 1-2, Marcel Dekker, New York. Banker G.S. and Rhodes C.T., Modern Pharmaceutics, Marcell Decker Inc., New

York. Bean, H.S., Beckett, A.H. and Carless, J.E.., Advances in Pharmaceutical Sciences, Academic Press Inc, London. www.google.com http://www.boomer.org/c/p1/ http://www.rxkinetics.com/pktutorial/1_1.html

E. Facilities Required

Indicate requirements for the Subject including size of classrooms and laboratories (i.e number of seats in classrooms and laboratories, extent of computer access etc.)

[1]. Accommodation (Lecture rooms, laboratories, etc.): 1 lecture room and 1 laboratory [2]. Computing resources: -- [3]. Other resources (specify --eg. If specific laboratory equipment is required, list

requirements or attach list): UV spectrophotometer, Dissolution apparatus, Ampoule Filling machine, Ampoule sealing machine, Mechanical and Magnetic stirrer etc.

F. Subject Evaluation and Improvement Processes [1]. Strategies for Obtaining Student Feedback on Effectiveness of Teaching: Feedbacks from the students are taken twice in a semester. [2]. Other Strategies for Evaluation of Teaching The system exists for class test followed by 2 Sessional Examinations per semester for evaluation of teaching.

G. List of Assignments: [1]. Aseptic Techniques

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School of Pharmacy Devi Ahilya Vishwavidyalaya, Indore

DETAILED COURSE PLAN

A. Subject Specification [1]. Subject title and code: Pharmaceutical Biotechnology (602T) [2]. Program(s) in which the Subject is offered: B. Pharm

(If general elective available in many programs indicate this rather than list programs) [3]. Name of faculty member responsible for the Subject : Mr. Gajanand Engla [4]. Level/year at which this Subject is offered : IIIrd Year (VIth Semester)

B. Objectives

[1]. Objective of the Subject: To understand and familiar with applications of Biotechnological tools in Immobilization

techniques in Enzymes & Cells, Vaccine design & production including MCAb, Fermentation & downstream processing for the biotech products, Gene Therapy, rDNA technology, microbial conversions, plant tissue cultures techniques & genetic modification in plants, and provide them an outline of biotechnology in today’s scenario.

At the end of the course, the student shall have acquired the competency in the selection or design of the proper tool or dosage form or delivery system for the delivery/ bioproduction of biologicals.

C. Subject Description [1]. Subject Detail

S. No.

Topic No. of Classes

01 Introduction, historical perspective, genomics, proteonomics and other biotechnology related techniques, scope and future of pharmaceutical biotechnology.

03

02 Enzyme immobilization: Introduction, factor affecting enzyme kinetics, Technique of immobilization of enzymes, immobilization of plant and bacterial cell, study of enzymes such as hyaluronidase, penicilllinase, streptokinase and steptodornase, amylase and protease, therapeutic applications of enzyme immobilization.

06

03 rDNA technology: Introduction, transformation, conjugation, transduction, protoplast fusion and plasmid mediated gene transfer, gene cloning including enzymes acting on DNA, cloning vectors, insertion of target DNA into vector, transformation and growth of cells, selection of recombinant clones and their applications, techniques of genetic engineering, study of drugs produced by biotechnology such as activase, humulin, humantrope, HB etc.

10

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04 Vaccine technology: Introduction, immunological principles, conventional vaccines, modern vaccine technologies, development of hybridoma for monoclonal antibodies and monoclonal antibody based pharmaceuticals, pharmaceutical considerations of vaccines.

05

05 Fermentation: Introduction to fermentation, fermenters and types of fermenters, factors affecting design of fermenter, the fermentation process and its optimization with special reference to ethyl alcohol, riboflavin, cephalosporin and ascorbic acid.

05

06 Production and downstream processing of biotech products: Introduction, production, downstream processing, issues to consider in production and purification of proteins, formulation of biotech products and its biopharmaceutical considerations, pharmacokinetics and pharmacodynamics of peptide and protein drugs.

04

07 Plant tissue culture: Introduction, laboratory requirements, cellular totipotency, types of cultures, protoplast fusion and somatic hybridization, transgenic plants and application of transgenic plants, cryopreservation and application of PTC in Pharmacy.

06

Revision/Interactive discussion-doubt solving session 02

Total No. of Classes 41

[1]. Subject Components (total contact hours): Lecture: 4 hrs. per week Practical: 6 hrs. per week Other: -

[2]. Development of Learning Outcomes in Domains of Learning

iii. Description of the knowledge to be acquired: Students were familiar with immobilization techniques, biosensors, vector, gene, gene cloning, MCAb, vaccines, vaccine production, gene based therapeutics (gene therapy), microorganism in bioconversions/ fermentations, Production and DSP of drugs by fermentation and PTC techniques and development of transgenic plants. iv. Teaching strategies to be used to develop that knowledge:

Power point presentation, Overhead projector, as and when needed chalk and talk, interactive discussion and assignments.

D. Learning Resources

i. Essential References, Required Text(s), Electronic Materials, Web Sites, Other learning material such as computer-based programs/CD, professional standards/regulations:

Vyas S.P. and Dixit V.K., Pharmaceutical Biotechnology, CBS Publishers and Distributors Pvt. Ltd., New Delhi.

Zito : Pharmaceutical Biotechnology

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Kokate C.R., Pharmaceutical Biotechnology Fundamentals & Applications, Nirali Prakashan, Pune

Walsh Gary Pharmaceutical Biotechnology-Concepts and Applications; University of Limerick, Republic of Ireland, John Wiley & Sons Ltd., England.

Khan, I. and Atiya, K. Emerging Trends in Bioinformatics, Ukaaz Publication, Hyderabad, India.

Thakur I. S., Industrial Biotechnology: Problems and Remedies, I.K. International Pvt. Ltd., New Delhi.

Gaud R.S., Gupta G.D. and Gokhale S.B., Practical Biotechnology, Nirali Prakashan, Pune.

Giri C.C., Giri A., Plant Biotechnology Practical Manuals, I.K. International Pvt. Ltd., New Delhi.

http://en.wikipedia.org/wiki/Biotechnology http://www.rpi.edu/dept/chem-eng/Biotech-Environ/IMMOB/goel2nd.htm http://en.wikipedia.org/wiki/Immobilized_enzyme http://gertrude-old.case.edu/276/materials/web/ImmobilizedEnzymeReview.pdf https://www.google.co.in/#q=enzyme+immobilization+ppt http://www.rpi.edu/dept/chem-eng/Biotech-Environ/Projects00/rdna/rdna.html http://en.wikipedia.org/wiki/Recombinant_DNA http://en.wikipedia.org/wiki/Gene_therapy http://en.wikipedia.org/wiki/Bio-fermentation_technology http://www.omicsonline.org/genetic-syndromes-gene-therapy.php http://www.path.org/projects/vaccine-technologies-overview.php http://www.biotechnologyforums.com/thread-1795.html http://en.wikipedia.org/wiki/Plant_tissue_culture http://ebookily.org/ppt/plant-tissue-culture-techniques

E. Facilities Required

Indicate requirements for the Subject including size of classrooms and laboratories (i.e number of seats in classrooms and laboratories, extent of computer access etc.)

[1]. Accommodation (Lecture rooms, laboratories, etc.): 1 lecture room and 1 laboratory [2]. Computing resources: -- [3]. Other resources (specify --eg. If specific laboratory equipment is required, list

requirements or attach list): Laminar airflow bench, Incubator, Binocular Microscope, Autoclave, Hot air oven, Micro-pipette, electrophoresis unit, Centrifuge, Micro-centrifuge, UV spectrophotometer, Refrigerator, etc.

F. Subject Evaluation and Improvement Processes [1]. Strategies for Obtaining Student Feedback on Effectiveness of Teaching: Feedbacks from the students are taken twice in a semester and class assignments were also given to students to check their learning. [2]. Other Strategies for Evaluation of Teaching As per system 2 Sessional examinations per semester for evaluation of teaching and in between sudden class test were also conducted to check effectiveness of learning.

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G. List of Assignments: Historical perspective, scope and

future of pharmaceutical biotechnology Enzyme immobilization techniques Therapeutic applications of enzymes rDNA technology Techniques of genetic engineering Study of few drugs produced by

biotechnology Vector in gene cloning Fermentation

Conventional v/s modern vaccine technologies

Hybridoma technology & MCAb based pharmaceuticals

Optimization of fermentation with reference to ethyl alcohol/ riboflavin

Downstream processing of biotech products

Plant tissue culture techniques Transgenic plants and their application.

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Devi Ahilya Vishwavidyalaya, Indore School of Pharmacy Detailed Course Plan

A. Subject Specification

[1]. Subject title and code: Pharmaceutical Chemistry-VI (Medicinal Chemistry –II) (603T) [2]. Program(s) in which the Subject is offered: B. Pharm

(If general elective available in many programs indicate this rather than list programs) [3]. Name Of Faculty Member Responsible For The Subject : Dr.E.MANIVANNAN [4]. Level/year at which this Subject is offered : B.Pharm Third Year (Sixth Semester)

B. Objectives

603T: Pharmaceutical Chemistry-VI (Medicinal Chemistry-II) subject is designed to expose undergraduate pharmacy (B.Pharm) students to the theory and practice of Medicinal Chemistry. This subject will emphasize the basics of medicinal chemistry, drug design and development, structure-activity relationship, biochemical mechanism of action of drugs, drug synthesis and applications of medicinal chemistry. In particular, the molecular aspects of drug action (chemical, physical, and biological) will be discussed in detail. Specific learning objectives: 1. The student should be able to understand and relate basic concepts in a variety of therapeutic (drugs) classes to their biological action. 2. The student should know the biochemical basis for some of the known mechanisms of drug action. 3. The student should understand the role of molecular modification (structure-activity relationship) in the development of new drugs; its successes, shortcomings and failures. 4. The student should be able to relate chemical structure to biological availability, biological activity, for some of the more important pharmacological classes like Central nervous system agents, steroidal drugs and hormonal system agents.

C. Subject Description

S.No. UNIT/TOPICS Hours Classification, synthesis of selective drugs, Structure activity relationship, pharmacological/biochemical mechanism of action, Therapeutic uses of following category of agents: (special emphasis should be given to specified drugs)

I. Drugs affecting central nervous system (A) General Anesthetics: Thiopental sodium, Ketamine Hydrochloride,

Methohexital, Sodium, Paraldehyde and Tribromoethanol.

02

(B) Sedatives and Hypnotics: phenobarbital, methylphenobarbital, allobarbital, butobarbitone, amobarbital, hexobarbital, pentobarbital

02

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sodium, cyclobarbital, Nitrazepam and Glutethimide. (C) Antiepileptic or anticonvulsant agents: Phenytoin Sodium,

Trimethadione, Phensuximide, Ethosuximide, Valproic Acid and Primidone.

03

(D) Opioid Analgesics: Morphine, Diamorphine Hydrochloride, Codeine, Levorphanol Tartrate, Dextromethorphan Hydrobromide, Pentazocine, Pethidine Hydrochloride, Fentanyl Citrate, Methadone Hydrochloride, Nalorphine Hydrochloride, and Naloxone Hydrochloride.

05

(E) Antiparkinsonian agents and Spasmolytic agents: Biperiden Hydrochloride, Trihexyphenidyl Hydrochloride, Benztropine Mesylate, Orphenadrine Citrate, Chlorphenoxamine Hydrochloride and Levodopa.

03

(F) CNS Stimulants: Caffeine, Theobromine, Nikethamide, Etamivan, Pentetrazol, Bemegride, and Methylphenidate.

02

(G) Psychopharmacological Agents: Neuroleptics, antidepressant and anxiolytic agents, (Nikethamide, Doxapram Hydrochloride, Dextroamphetamine Sulphate, Pentylenetetrazole, Amitriptyline Hydrochloride, Imipramine Hydrochloride, Doxepin Hydrochloride, Phenyclidine , Tetrahydrocannabinol, Chloropromazine Hydrochloride, Triflupromazine, Thioridazine Hydrochloride, Prochlorperazine Maleate, Trifluoperazine, Hydrochloride, Thiothixene, Haloperidol, Droperidol, Resperidone, Chlordiazepoxide, Diazepam, Oxazepam, Lorazepam, Halazepam, Flurazepam and Alprazolam).

05

II. Drugs affecting Hormonal System (A) Thyroid hormones and Antithyroid agents: Biosynthesis of thyroid hormones, Propythiouracil, Methimazole, Carbimazole and I131

03

(B) Insulin and Oral Hypoglycaemic agents: Chemistry of Insulin and its preparations, (Chlorpropamide, Tolbutamide, Glimepride, Glipizide, Rosiglitazone, Pioglitazone, Metformin, Phenformin, Acarbose, Miglitol, Repaglinide).

04

(C) Steroidal agents: Steroidal nomenclature, Stereochemistry, Biosynthesis, Interconversions of androgens, estrogens, progesterones and adrenocorticoids, Androsterone, testosterone, estrone, estriol, estradiol, diethylstilbesterol, progesterone, cortisone, prednisolone and Dexamethasone.

05

III. Drugs affecting Haematopietic System: Antithrombotic, Thrombolytic and Anticoagulant agents (Warfarin Sodium, Protamine Sulphate, Dicoumarol, Phenindione, and Anisindione).

03

IV. Chemistry and physiological importance of water & lipid soluble Vitamins.

03

General Discussion, revision of topics, and Quiz 05 TOTAL HOURS 45

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[1]. Subject Components (total contact hours):

Lecture: 4 hrs. per week Practical: 6 hrs. per week Other: - 05 (General Discussion, revision of topics, and Quiz)

[2]. Development of Learning Outcomes in Domains of Learning

Description of the knowledge to be acquired: The student should be able to relate chemical structure to biological availability, biological activity, for some of the more important pharmacological classes like Central nervous system agents, steroidal drugs and hormonal system agents.

i. Teaching strategies to be used to develop that knowledge: Black board teaching, General discussion of drugs, Interactive classes, Learning through internet, Group discussion, Assignments and single drug presentation by students.

D. Learning Resources

i. Essential References, Required Text(s), Electronic Materials, Web Sites, Other learning material such as computer-based programs/CD, professional standards/regulations: BOOKS RECOMMENDED

1. Foye, W.O., Principles of Medicinal Chemistry, Lea and Febiger, Philadelphia. 2. Delagado, J.N. and Remers, W.A.R, Wilson and Giswold’s Text Book of Organic,

Medicinal and Pharmaceutical Chemistry, J. Lippincott Co., Philadelphia. 3. Patrick, G., An Introduction to Medicinal Chemistry, Scientific Distributors, Mumbai. 4. Wolff, M.E. Ed., Burger’s Medicinal Chemistry, John Wiley and Sons, New York. 5. Singh, H., Kapoor, V.K. Medicinal and Pharmaceutical Chemistry,Vallabh Prakashan,

New Delhi. 6. Nogrady, T., Medicinal Chemistry-A Biochemical Approach, Oxford University Press,

New York, Oxford. 7. Thomas, G., Introduction to Medicinal Chemistry, CBS Publishers and Distributors,

New Delhi. 8. Lednicer, D., The Organic Chemistry of Drug Synthesis, Volume 1-6, John Wiley and

sons Inc., New York. 9. Kar, A., Medicinal Chemistry, Willey Eastern Ltd., New Delhi. 10. Pandya, S.N., Textbook of Medicinal Chemistry, SG Publisher, Varanasi. Web Sites:

http://global.oup.com/uk/orc/chemistry/patrick4e/ http://home.nas.net/~dbc/cic_hamilton/med.html http://pubs.acs.org/journal/jmcmar http://www.sciencedirect.com/science/journal/0960894X http://pubs.rsc.org/en/journals/journalissues/md#!recentarticles&all http://www.journals.elsevier.com/european-journal-of-medicinal-chemistry/

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E. Facilities Required Indicate requirements for the Subject including size of classrooms and laboratories (i.e number of seats in classrooms and laboratories, extent of computer access etc.)

[1]. Accommodation (Lecture rooms, laboratories, etc.): 1 lecture room and 1 laboratory [2]. Computing resources: - Nil [3]. Other resources (specify --eg. If specific laboratory equipment is required, list

requirements or attach list): Basic Pharmaceutical Chemistry Laboratory facilities are needed for practical.

F. Subject Evaluation and Improvement Processes [1]. Strategies for Obtaining Student Feedback on Effectiveness of Teaching: Student Feedbacks of teachers obtained from the students twice in a semester and analysed graphically. [2]. Other Strategies for Evaluation of Teaching The university system of evaluation through two sessional examinations and a semester for evaluation of teaching.

G. List of Assignments:

List of selected category of drugs, their chemistry and mechanism of action

(A) Opioid Receptor mechanism, agonists and Antagonists (B) Stereochemistry and Nomenclature and biosynthesis of Steroids (C) Chemistry, SAR and Mechanism of action of Sulfonyl ureas as Anti-diabetes agents (D) Etiology of Parkinson’s disease (PD’s) and the role of MPTP in PD’s.

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School of Pharmacy Devi Ahilya Vishwavidyalaya, Indore

DETAILED COURSE PLAN

A. Subject Specification

Subject title and code:PHARMACEUTICS -IX (PACKAGING TECHNOLOGY)-604 T

[1]. Program(s) in which the Subject is offered: B. Pharm (If general elective available in many programs indicate this rather than list programs)

[2]. Name of faculty member responsible for the Subject : Mr. Mayank Sharma [3]. Level/year at which this Subject is offered : Third Year

B. Objectives

[1]. Objective of the Subject: To Demonstrate an in-depth understanding the concept of Packaging of

pharmaceutical dosage form

To Demonstrate a systematic and critical understanding of various dosage form

packaging material and their Technology

To make students aware with the new trends in Packaging Technology

C. Subject Description

[1]. Subject Detail S. No. Topic No. of Classes 01 Packaging of pharmaceutical dosage form: Introduction,Definition

and function,Regulatory requirements, Nature of package evaluation, Types of packaging.

08

02 Packaging of solid oral dosage form: Scope, Packaging, stability and shelf life of containers and closures, Unit dosage packaging.

06

03 Packaging of semisolids and topical: Scope, regulatory requirements, containers and closures.

06

04 Glass packaging materials: Containers and closures, Glass as a packaging material, composition and types.

06

05 Plastic packaging materials: Containers and closures, introduction, classification of plastic materials.

04

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06 Metal packaging materials: Containers and closures, Introduction, Modern packaging metal, Tinplate and associated materials aluminium.

05

07 Tamper-resistant packaging: Introduction, Film wrapper, Blister package, Strip package, Bubble pack, foil, pouches, bottle seals and tape seals.

03

08 Child resistant package 02 Total No. of Classes 40

[2]. Subject Components (total contact hours):

Lecture: 4 hrs. Per week Practical:- Nil Other: -Nil

[3]. Development of Learning Outcomes in Domains of Learning

i. Description of the knowledge to be acquired: To Demonstrate an in-depth understanding the concept of Packaging of

pharmaceutical dosage form To Demonstrate a systematic and critical understanding of various dosage form

packaging material and their Technology To Demonstrate a systematic and critical understanding of Packaging Technology To make students aware with the new trends in Packaging development & research

ii. Teaching strategies to be used to develop that knowledge: Black board teaching, Group discussion, Assignments.

D. Learning Resources

i. Essential References, Required Text(s), Electronic Materials, Web Sites, Other learning material such as computer-based programs/CD, professional standards/regulations:

1. Dean, D.A., Evans, E.R., Hall, I.H., Pharmaceutical Packaging Technology, London and New York.

2. Lachman, L., Lieberman, H.A. and Kanig, J.L., The Theory and Practice of Industrial Pharmacy, Varghese Publishing House, Mumbai.

3. Harburn Kenneth, Quality Control of Packaging materials in the Pharmaceutical Industry. 4. Brody, A. L. and Marsh, K.S., Encyclopedia of Packaging Technology, John Wiley and

sons, New York. www.google.com norris.usc.libguides.com/Pharmacol_and_PharmSci

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www.iseek.org/education/pharma explorehealthcareers.org › Careers › Pharmacy

E. Facilities Required

Indicate requirements for the Subject including size of classrooms and laboratories (i.e. number of seats in classrooms and laboratories, extent of computer access etc.)

[1]. Accommodation (Lecture rooms, laboratories, etc.): 1 lecture room and 1 laboratory [2]. Computing resources: --overhead projector, 1 computer unit [3]. Other resources (specify --eg. If specific laboratory equipment is required, list

requirements or attach list)

F. Subject Evaluation and Improvement Processes

[1]. Strategies for Obtaining Student Feedback on Effectiveness of Teaching: Feedbacks from the students are taken twice in a semester. [2]. Other Strategies for Evaluation of Teaching The system exists for class test followed by 2 sessional examinations per semester for evaluation of teaching.

G. List of Assignments:

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School of Pharmacy Devi Ahilya Vishwavidyalaya, Indore

DETAILED COURSE PLAN

A. Subject Specification [1]. Subject title and code: Pharmacology- II (605T) [2]. Program(s) in which the Subject is offered: B. Pharm

(If general elective available in many programs indicate this rather than list programs) [3]. Name of faculty member responsible for the Subject : Mr. Manoj Rathore [4]. Level/year at which this Subject is offered : Third Year

B. Objectives

[1]. Objective of the Subject: The objective is to understand the mechanism of action, pathophysiology of diseases,

classification of various drugs, signs and symptoms of various diseases. At the end of the course, the student shall have acquired proper knowledge of various

drugs and the treatment of the various diseases, dosage regimen, adverse effects of the drugs, drug contraindications.

C. Subject Description S.No. Topic/ unit No. of lectures

required 1 Pathophysiology of CNS diseases and pharmacology of drugs used to

treat them --

(i) Neurohumoral transmission in CNS: Cholinergic pathways, Dopaminergic pathways, Serotonergic pathways, Noradrenergic pathways.

4

(ii) . General anesthetics, alcohol and disulfiram. 2 (iii) Hypnotics, sedatives, anti-anxiety agents, and centrally acting muscle

relaxants. 2

(iv) Psychopharmacological agents: Antipsychotics, Antidepressants, Antimanics and Hallucinogens.

3

(v) Antiepileptic drugs 2 Narcotic analgesics and antagonists 1 (vi) Drugs used in neurodegenerative diseases: Parkinson’s disease and

Alzheimer’s disease 2

( vii) Drug addiction and drug abuse: Alcohol, Nicotine and Cannabis. 2 (viii) CNS stimulants 1

2. Pathophysiology of diseases of endocrine system and pharmacology of

drugs used for their treatment 1

(ii) Hypothalamic and pituitary hormones. 2 (iii) Thyroid hormones and anti thyroid drugs. 2

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(iv) Insulin, oral hypoglycemic agents and glucagons. 2 (v) Corticosteroids. 1 (vi) Androgens, anabolic steroids and drugs for erectile dysfunction. 2 (vii) Estrogens, progestins and oral contraceptives. 2 (vii) Oxytocin and drugs acting on the uterus. 1 (viii) Parathormone, calcitonin and vitamin D, ACTH and corticosteroids 2 3. Drug acting on Haematopoietic system 2 (i) Haematinics (pathophysiology of anaemia) 2 (ii) Anticoagulants 1 (iii) Fibrinolytic and antiplatelet drugs 2 (iv) Blood and plasma volume expanders. 1 Total lectures 41

[1]. Subject Components (total contact hours):

Lecture: 4 hrs. per week Practical: 6 hrs. per week Other: -

[2]. Development of Learning Outcomes in Domains of Learning

i. Description of the knowledge to be acquired: • To understand the fundamental scientific principles of drug action and the various mechanisms by which drugs can mediate their pharmacological effect • To understand the biochemical reactions that result in the metabolism of drugs within the body • To understand the rationale behind designing different dosing regimens of particular drugs in specific patient populations • To understand how specific patient characteristics and genetics can affect the response to a particular class of drugs

ii. Teaching strategies to be used to develop that knowledge: Black board teaching, Power point presentation, Overhead projector, Group discussion, Assignments.

D. Learning Resources

i. Essential References, Required Text(s), Electronic Materials, Web Sites, Other learning material such as computer-based programs/CD, professional standards/regulations:

1. Rang, H.P., Dale, M.M., Riter, J.M. and Flower, R.J., Rang and Dale’s Pharmacology, Churchill Livingstone, Philadelphia. 2. Katzung, B.G., Basic and clinical pharmacology. The McGraw Hill Companies, USA. 3. Kumar, V., Abbas, A.K., Fausto, N., Robbins and Cotran Pathologic basis of disease

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Saunders, Pennsylvania. 4. Barar, F.S.K., Essentials of therapeutics. S. Chand and Company (P) Ltd., New Delhi. 5. Seth, S.D., Textbook of Pharmacology. Elsevier, New Delhi. 6. Tripathi, K.D., Essentials of Medical Pharmacology. Jaypee Brothers Medical Publishers

(P) Ltd., New Delhi. 7. Satoskar, R.S., Bhandarkar, S.D., Rege, N.N., Pharmacology and Pharmacotherapeutics, Popular Prakashan, Mumbai.

Web resources www.google.com www.wikipidea.com www.expertconsultbook.com www.emedicinehealth.com www.jfmed.com www.webmd.com

E. Facilities Required

Indicate requirements for the Subject including size of classrooms and laboratories (i.e number of seats in classrooms and laboratories, extent of computer access etc.)

[1]. Accommodation (Lecture rooms, laboratories, etc.): 1 lecture room and 1 laboratory [2]. Computing resources: -- [3]. Other resources (specify --eg. If specific laboratory equipment is required, list

requirements or attach list): Actophotometer, Rotarod apparatus, elevated plus maze light and dark box model, glasswares, syringes,equipments,etc.

F. Subject Evaluation and Improvement Processes [1]. Strategies for Obtaining Student Feedback on Effectiveness of Teaching: Feedbacks from the students are taken twice in a semester. [2]. Other Strategies for Evaluation of Teaching The system exists for class test followed by 2 sessional examinations per semester for evaluation of teaching.

G. List of Assignments:

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School of Pharmacy Devi AhilyaVishwavidyalaya, Indore

A. Subject Specification [1]. Subject title and code:Communication Skills & Personality Development-VI (606P) [2]. Program(s) in which the Subject is offered: B. Pharm [3]. Name of faculty member responsible for the Subject :Dr. Mrs. Anupama A. Parate [4]. Level/year at which this Subject is offered :Third Year

B. Objectives

[1]. Objective of the Subject:

This subject aims at improving and grooming the presentation skills which include audio-

video presentations, their significance and role in the industry. The subject also emphasizes on

structure strategies and dynamics of team work and group discussions.

C. Subject Description [1]. Subject Details

S. No. Topic Number of lectures allotted

1.

Public speaking and presentation skills: Characteristics, types, modes of delivery elements

of high impact presentation, preparation of power-point

Overhead projector presentations Video conferencing

08

2.

Group discussion, debate and extempore: Structure, strategies, dynamics of group discussion,

intervention, summarizing Modulation of voice, body language, relevance,

fluency, coherence Team work in a group discussion Mock group discussion (GD). (Seminars on related

topics)

12

Total 20

[1]. Subject Components (total contact hours): Lecture: -- Practical: 02 hrs./ week Other: -

[2]. Development of Learning Outcomes in Domains of Learning

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i. Description of the knowledge to be acquired:

Public speaking and presentation skills , audio-visual presentations.

Group discussion, debate and extempore.

ii. Teaching strategies to be used to develop that knowledge: Black board teaching, PowerPoint Projector,Overhead projector, Group discussion,

Assignments.

D. Learning Resources Huckin, T.N. and Olsen, L.A., Technical Writing and Professional Communication,

McGraw-Hill, Inc., New Delhi. Gerson, S.J. and Gerson, S.M., Technical Writing, Pearson Education Asia, Hong Kong. Esenberg, A., A Beginner’s Guide to Technical Communication, McGraw-Hill, New

Delhi. Rutherford, A.J. Basic Communication Skills for Technology, Pearson Education Asia,

Hong Kong. Lesikar, R.V. Perrit, J.D. and Flately, M.E., Lesikar’s Basic Business Communication,

McGraw-Hill, New Delhi. Bovee, C.L., Thill, J.V. and Schatzman, B., Business Communication Today, Pearson

Education Asia, Hong Kong. Ober, S., Contemporary Business Communication, Houghton Mifflin Company, Wiley-

Dreamtech, New York.

E. Facilities Required

Indicate requirements for the Subject including size of classrooms and laboratories (i.e number of seats in classrooms and laboratories, extent of computer access etc.)

[1]. Accommodation (Lecture rooms, laboratories, etc.): 1 lecture room [2]. Computing resources: -- [3]. Other resources (specify --eg. If specific laboratory equipment is required, list

requirements or attach list): -

F. Subject Evaluation and Improvement Processes [1]. Strategies for Obtaining Student Feedback on Effectiveness of Teaching: Feedbacks from the students are taken twice in a semester. [2]. Other Strategies for Evaluation of Teaching On the basis of assignments, routine practical classes and submission at the end of semester.

G. List of Assignments: 1. Preparation of PowerPoint presentation (Slide Preparation). 2. Preparation of overhead projector presentation (OHP Sheets Preparation).