conduction of nerve impulse & synaps

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Page 1: conduction of nerve impulse & synaps
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NEURAL SYSTEM & ENDOCRINE SYSTEM

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The neural system of all animals is composed of highly specialised cells called neurons.

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Central nervous peripheral nervous

system (CNS) system(PNS)

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The afferent nerve fibres transmit impulses from tissues/organs to the CNS.

The efferent fibres transmit regulatory impulses from the CNS to the concerned peripheral tissues/organs. relays impulses

The somatic neural system relays impulses ;- CNS skeletal muscles.

The autonomic neural system transmits impulses;- CNS involuntary organs and smooth muscles of the body.

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1) Myelinated Nerve Fibres (with myelin sheth)

2)Nonmyelinated Nerve Fibres(without myelin sheth)

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A neuron is a microscopic structure composed of followings:-

i) Cell body ii) Dendrites iii) Axon The cell body contains cytoplasm with typical cell

organelles and certain granular bodies called Nissl’s granules. Short fibres which branch repeatedly and

project out of the cell body also contain Nissl’s granules and

are called dendrites. These dendrites transmit impulses towards the cell

body.

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The axon is a long fiber, the distal end of which is branched. Each branch terminates as a bulb-like structure called synaptic knob.

It contains synaptic vesicles containing chemicals called neurotransmitters.

The axons transmit nerve impulses away from the cell body to a synapse or to a neuromuscular junction.

The myelinated nerve fibres are enveloped with Schwann cells, which form a myelin sheath around the axon.

The gaps between two adjacent in myeline sheaths are called nodes of Ranvier.

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DIAGRAMMATIC REPRESENTATION OF NERVE IMPULSE

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The electrical potential difference across the plasma membrane at the site A is called the action potential, which is in fact termed as a nerve impulse.

At sites immediately ahead, the axon (e.g., site B) membrane has a positive charge on the outer surface and a negative charge on its inner surface.

As a result, a current flows on the inner surface from site A to site B. On the outer surface current flows from site B to site A to complete the circuit of current flow. Hence, the polarity at the site is reversed,

An action potential is generated at site B. Thus, the impulse (action potential) generated at site A arrives at site B.

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The sequence is repeated along the length of the axon and consequently the impulse is conducted.

The rise in the stimulus-induced permeability to Na+ is extremely short lived.

It is quickly followed by a rise in permeability to K+. Within a fraction of a second, K+ diffuses outside the membrane and restores the resting potential of the membrane at the site of excitation and the fibre becomes once more responsive to further stimulation.

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A nerve impulse is transmitted from one neuron to another through junctions called synapses.

A synapse is formed by the membranes of a pre-synaptic neuron and a post-synaptic neuron,

which may or may notbe separated by a gap called synaptic cleft.

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At electrical synapses, the membranes of pre- and post-synaptic neurons are in very close proximity.

Electrical current can flow directly from one neuron into the other across these synapses.

Transmission of an impulse across electrical synapses is very similar to impulse conduction along a single axon.

Impulse transmission across an electrical synapse is always faster than that across a chemical synapse.

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