color vision fundamentals · 20 hereditary color deficiency 8-10% of males and 1/200 females (0.5%)...

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1 Color Vision Fundamentals Jeff Rabin, OD, PhD Chief, Visual Function Laboratory Ophthalmology Branch USAF School of Aerospace Medicine

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Page 1: Color Vision Fundamentals · 20 Hereditary Color Deficiency 8-10% of males and 1/200 females (0.5%) are born with red or green color deficiency. Sex-linked recessive condition (X

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Color Vision Fundamentals

Jeff Rabin, OD, PhD

Chief, Visual Function Laboratory

Ophthalmology Branch

USAF School of Aerospace Medicine

Page 2: Color Vision Fundamentals · 20 Hereditary Color Deficiency 8-10% of males and 1/200 females (0.5%) are born with red or green color deficiency. Sex-linked recessive condition (X

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Visible light is small part of electromagnetic spectrum.

700 600 500 400

UV IR

Page 3: Color Vision Fundamentals · 20 Hereditary Color Deficiency 8-10% of males and 1/200 females (0.5%) are born with red or green color deficiency. Sex-linked recessive condition (X

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The visible spectrum includes 300

wavelengths (400-700 nm), and in some

portions we can discern color differences

of 1 wavelength. The ability to see so

many colors depends on:

a. a separate cone for each wavelength.

b. optic nerve fibers for each color.

c. visual cortex neurons sensitive to each

color.

d. difference in stimulation of red, green

and blue sensitive cones.

Page 4: Color Vision Fundamentals · 20 Hereditary Color Deficiency 8-10% of males and 1/200 females (0.5%) are born with red or green color deficiency. Sex-linked recessive condition (X

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Red cones

Green cones

Blue cones

Brightness = R + G

Color = R – G

Color = B – (R+G)

Red cones

outnumber green

cones 2/1

Red + Green cones

outnumber blue

cones 10/1

Retinal Cones–Normal Color Vision

Blue cones

absent in

central fovea

Page 5: Color Vision Fundamentals · 20 Hereditary Color Deficiency 8-10% of males and 1/200 females (0.5%) are born with red or green color deficiency. Sex-linked recessive condition (X

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Red, green and

blue cone

sensitivity vs.

wavelength

curves

Retinal Cones–Normal Color Vision

Page 6: Color Vision Fundamentals · 20 Hereditary Color Deficiency 8-10% of males and 1/200 females (0.5%) are born with red or green color deficiency. Sex-linked recessive condition (X

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What happens in hereditary

color deficiency?

Red or green cone peak

sensitivity is shifted.

Red or green cones absent.

Page 7: Color Vision Fundamentals · 20 Hereditary Color Deficiency 8-10% of males and 1/200 females (0.5%) are born with red or green color deficiency. Sex-linked recessive condition (X

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B R G

437 nm 564 nm

533 nm

NORMAL CONE SENSITIVITY CURVES

(TRICHROMAT)

Page 8: Color Vision Fundamentals · 20 Hereditary Color Deficiency 8-10% of males and 1/200 females (0.5%) are born with red or green color deficiency. Sex-linked recessive condition (X

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B R G

437 nm 564 nm

Deuteranomaly

(green shifted toward red)

5% of Males

Page 9: Color Vision Fundamentals · 20 Hereditary Color Deficiency 8-10% of males and 1/200 females (0.5%) are born with red or green color deficiency. Sex-linked recessive condition (X

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B R G

437 nm 564 nm

Deutan Dichromat

(no green cones; only red and blue)

1% of Males

Page 10: Color Vision Fundamentals · 20 Hereditary Color Deficiency 8-10% of males and 1/200 females (0.5%) are born with red or green color deficiency. Sex-linked recessive condition (X

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B R

437 nm 564 nm

Deutan Dichromat

(no green cones; only red and blue)

1% of Males (there is no green curve)

Page 11: Color Vision Fundamentals · 20 Hereditary Color Deficiency 8-10% of males and 1/200 females (0.5%) are born with red or green color deficiency. Sex-linked recessive condition (X

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B R G

437 nm

533 nm

Protanomalous

(red shifted toward green)

1% of Males

Page 12: Color Vision Fundamentals · 20 Hereditary Color Deficiency 8-10% of males and 1/200 females (0.5%) are born with red or green color deficiency. Sex-linked recessive condition (X

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B R G

437 nm

533 nm

Protan Dichromat

(no red cones; only green and blue)

1% of Males

Page 13: Color Vision Fundamentals · 20 Hereditary Color Deficiency 8-10% of males and 1/200 females (0.5%) are born with red or green color deficiency. Sex-linked recessive condition (X

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B G

437 nm

533 nm

Protan Dichromat

(no red cones; only green and blue)

1% of Males (there is no red curve)

Page 14: Color Vision Fundamentals · 20 Hereditary Color Deficiency 8-10% of males and 1/200 females (0.5%) are born with red or green color deficiency. Sex-linked recessive condition (X

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Why do colors that

look different to us

appear the same to

color deficient

individuals?

Page 15: Color Vision Fundamentals · 20 Hereditary Color Deficiency 8-10% of males and 1/200 females (0.5%) are born with red or green color deficiency. Sex-linked recessive condition (X

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B R G

Color Normal Individual

Large difference

in stimulation of

green and red

cones

Small

difference in

stimulation

Consider a green vs.

yellow light…

The two spots

appear different

in color because

R-G is large for

one, and small

for the other.

Page 16: Color Vision Fundamentals · 20 Hereditary Color Deficiency 8-10% of males and 1/200 females (0.5%) are born with red or green color deficiency. Sex-linked recessive condition (X

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B R G

Deuteranomaly

Small

difference in

stimulation

Small

difference in

stimulation

Each spot produces the same R-G stimulation and thus

looks the same!

(the green sensitivity curve is shifted toward the red)

Look the same!

Page 17: Color Vision Fundamentals · 20 Hereditary Color Deficiency 8-10% of males and 1/200 females (0.5%) are born with red or green color deficiency. Sex-linked recessive condition (X

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Some Views With and Without

Color Vision

Link Jay and Maureen Neitz Color Vision Page

Page 18: Color Vision Fundamentals · 20 Hereditary Color Deficiency 8-10% of males and 1/200 females (0.5%) are born with red or green color deficiency. Sex-linked recessive condition (X

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Drs. Jay and Maureen Neitz

Department of Cell Biology, Neurobiology & Anatomy

Department of Ophthalmology

Medical College of Wisconsin

Page 19: Color Vision Fundamentals · 20 Hereditary Color Deficiency 8-10% of males and 1/200 females (0.5%) are born with red or green color deficiency. Sex-linked recessive condition (X

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Color Labeling

Color deficients rely heavily

on context and learning—

apple is “red” because

patient learns to call it red

—same hue may appear

gray when presented

without other cues.

For wavelengths beyond

545, relative brightness,

context, and learning play a

significant role verbal label

and response.

Page 20: Color Vision Fundamentals · 20 Hereditary Color Deficiency 8-10% of males and 1/200 females (0.5%) are born with red or green color deficiency. Sex-linked recessive condition (X

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Hereditary Color Deficiency

8-10% of males and 1/200 females (0.5%) are

born with red or green color deficiency.

Sex-linked recessive condition (X chromosome).

Protanomaly—red cone peak shifted toward

green (1%)

Protan Dichromat—red cones absent (1%)

Deuteranomaly—green cone peak shifted

toward red (5%)

Deutan Dichromat—green cones absent (1%)

Hereditary tritan defects are rare (0.008%)

Page 21: Color Vision Fundamentals · 20 Hereditary Color Deficiency 8-10% of males and 1/200 females (0.5%) are born with red or green color deficiency. Sex-linked recessive condition (X

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Color Deficiency Males Females

Protanopia 1% 0.01%

Deuteranopia 1% 0.01%

Protanomaly 1% 0.01%

Deuteranomaly 5% 0.4%

Overall (red-green) 8% 0.5%

Tritanopia 0.008% 0.008%

Tritanomaly Rare Rare

Rod

monochromatism

Rare Rare

Cone

monochromatism

Rare Rare

Page 22: Color Vision Fundamentals · 20 Hereditary Color Deficiency 8-10% of males and 1/200 females (0.5%) are born with red or green color deficiency. Sex-linked recessive condition (X

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END SLIDE SHOW

OF COLOR VISION

FUNDIMENTALS