cheminform abstract: facile nucleophilic fluorination of primary alkyl halides using...

ChemInform 2010, 41, issue 15 © 2010 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim www.cheminform.wiley-vch.de Halogen compounds Q 0790 DOI: 10.1002/chin.201015090 Facile Nucleophilic Fluorination of Primary Alkyl Halides Using Tetrabutylam- monium Fluoride in a tert-Alcohol Medium. — Bu4NF in tert-amyl alcohol is found to be an efficient fluorinating agent for 3-halopropylnapthalenes. Depending on the halogen, the nucleophilic substitution can be accompanied by considerable amount of elimination product. — (KIM*, D. W.; JEONG, H.-J.; LIM, S. T.; SOHN, M.-H.; Tetrahedron Lett. 51 (2010) 2, 432-434; Dep. Nucl. Med., Res. Inst. Clin. Med., Sch. Med., Chonbuk Natl. Univ., Jeonju 561-712, S. Korea; Eng.) — Mais 15- 090

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Page 1: ChemInform Abstract: Facile Nucleophilic Fluorination of Primary Alkyl Halides Using Tetrabutylammonium Fluoride in a tert-Alcohol Medium

www.cheminform.wiley-vch.de

Halogen compoundsQ 0790 DOI: 10.1002/chin.201015090

Facile Nucleophilic Fluorination of Primary Alkyl Halides Using Tetrabutylam-monium Fluoride in a tert-Alcohol Medium. — Bu4NF in tert-amyl alcohol is found to be an efficient fluorinating agent for 3-halopropylnapthalenes. Depending on the hal-ogen, the nucleophilic substitution can be accompanied by considerable amount of elimination product. — (KIM*, D. W.; JEONG, H.-J.; LIM, S. T.; SOHN, M.-H.; Tetrahedron Lett. 51 (2010) 2, 432-434; Dep. Nucl. Med., Res. Inst. Clin. Med., Sch. Med., Chonbuk Natl. Univ., Jeonju 561-712, S. Korea; Eng.) — Mais

15- 090

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