cheminform abstract: convenient preparation of cycloalkenyl boronic acid pinacol esters
TRANSCRIPT
www.cheminform.wiley-vch.de
Organo-boron compoundsS 0040 Convenient Preparation of Cycloalkenyl Boronic Acid Pinacol Esters. — Title
compounds (V), useful intermediates for subsequent Suzuki—Miyaura cross-coupling, are obtained from the corresponding cycloalkanones (I) via Shapiro reaction of cyclo-alkyl hydrazones (III) followed by trapping with borate ester (IV). The method avoids the expensive transition metal-catalyzed borylation of alkenyl halides or triflates and is readily scalable to multigram quantities. — (RAUNIYAR, V.; ZHAI, H.; HALL*, D. G.; Synth. Commun. 38 (2008) 22, 3984-3995; Dep. Chem., Univ. Alberta, Edmonton, Alberta T6G 2G2, Can.; Eng.) — H. Haber
17- 174
ChemInform 2009, 40, issue 17 © 2009 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim