chemical level of organization - noel ways

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Anatomy and Physiology I Student Outline – Chemistry of Life Page 1 Chemical Level of Organization 1. Introduction to Atoms and Molecules A. Atoms i. Nucleus a. Protons b. Neutrons ii. Shells a. Electrons b. Electron Shell filling: 2-8-8-8 iii. Examples H = hydrogen C = carbon Na = sodium N = nitrogen Ca = calcium Fe = iron K = potassium Cl = chlorine P = phosphorus

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Anatomy and Physiology I Student Outline – Chemistry of Life

Page 1

Chemical Level of Organization 1. Introduction to Atoms and Molecules

A. Atoms i. Nucleus

a. Protons b. Neutrons

ii. Shells

a. Electrons b. Electron Shell filling: 2-8-8-8

iii. Examples H = hydrogen C = carbon Na = sodium N = nitrogen Ca = calcium Fe = iron K = potassium Cl = chlorine P = phosphorus

Anatomy and Physiology I Student Outline – Chemistry of Life

Page 2

B. Compounds

i. Inorganic Compounds

ii. Organic Compounds

a. Carbon

C. Bonding

i. Ionic

ii. Atomic Stability

Anatomy and Physiology I Student Outline – Chemistry of Life

Page 3

a. Example:

Table Salt

ii. Covalent Bond

2. Chemical Reaction • chemical equation

reactant reactant product H+ + OH- à H2O CO2 + H2O à H2CO3 H2CO3 à H+ + HCO3 - Molecular Formula

Note: arrow ( à) indicated direction of reaction.

A. Common Chemical Reactions i. Synthesis Reaction

• anabolic ( A + B à AB )

OH- + H+ à H2O CO2 + H2O à H2CO3

Anatomy and Physiology I Student Outline – Chemistry of Life

Page 4

ii. Decomposition Reaction • Catabolic ( AB à A + B )

H2CO3 à H+ + HCO3 -

H2CO3 à H2O + CO2

iii. Oxidation-Reduction Reactions

a. Oxidized b. Reduced

B. Chain Reactions

Anatomy and Physiology I Student Outline – Chemistry of Life

Page 5

C. Reversibility of Reactions

Anatomy and Physiology I Student Outline – Chemistry of Life

Page 6

D. Reaction Rate

i. Temperature ii. Concentration iii. Enzyme Catalysts (Pull out handout on enzymes)

a. Enzyme b. Substrate c. Enzyme-Substrate Complex d. Products

3. Inorganic Compounds A. Water

i. Polar ii. Hydrogen Bonds

Anatomy and Physiology I Student Outline – Chemistry of Life

Page 7

iii. Water as a “Universal Solvent”

= Na+ = Cl- = water

B. Water Characteristics

i. “Universal Solvent” a. Solvent b. Solute c. Solution d. Suspension

ii. Lubricant iii. Heat Distribution iv. High Heat of Vaporization

C. Salt

• Electrolytes D. Inorganic Acids and Bases (see handout on Acids and Bases)

• Ionization or Dissociation • Electrolytes

i. Acids - If the cation is a H+

HCl à H+ + Cl- proton anion (cation)

ii. Base - If the anion is an OH-

NaOH à Na+ + OH- cation hydroxyl ion

iii. Neutralization

+ -

- -

-+

- + - + -+ - + - +- + - + -+ - + - +

- + - + -+ - + - +- + - + -+ - + - +

+

+

+

Anatomy and Physiology I Student Outline – Chemistry of Life

Page 8

E. Buffer Systems (See handout and video) If we do not cover this topic in lecture, do this on your own using the video. There will be a guided essay on this topic.

4. ORGANIC COMPOUNDS 5. Organic Compound

Classifications

A. Carbohydrates (Pull out your “Carbohydrate” handout)

i. Monosaccharides (see handout)

a. Glucose

b. Fructose

c. Galactose

ii. Disaccharides (see handout)

a. Maltose – glucose + glucose

b. Sucrose – glucose + fructose

c. Lactose - glucose + galactose

iv. Polysaccharides (see handout) a Starch b. Glycogen c. Cellulose

Monomer

Dimer

Trimer

Quadramer

Pentamer

Hexamer

ETC ETC

Anatomy and Physiology I Student Outline – Chemistry of Life

Page 9

• Fiber C. Lipids

i. Components a. Glycerol b. Fatty Acids

c. Glycerides

ii. Classifications a. Fats b. Oils c. Saturated Fat

Anatomy and Physiology I Student Outline – Chemistry of Life

Page 10

d. Monounsatrauted Fat e. Polyunsaturated Fat

iii. Phospholipids

** ESSAY ** Emulsification (SEE “EMULSIFICATION” Handout)

iv. Steroids

• Cholesterol

D. Proteins (SEE HANDOUT: “PROTEIN AND DENATURATION”) i. Classifications

a. Dipeptide b. Tripeptide

CH3

CH3

CH2OH

C OOH

HO

Cortisol

CH3

CH3

CH2

CH3CH3

CH3CH

CH2

CH2

CH

HO

Cholesterol HOC

CH2OH

CO

OH

HO

Aldosterone

RNH2 C

H

CO

OH

Basic Amino Acid

Radical Group

Hydrogen

Acid Group Amino Group

H

NH2 C

H

CO

OH

Glycine

3CH

NH2 C

H

CO

OH

Alanine

2CH

NH2 C

H

OH

CO

OH

Serine

3CH

OH

NH2 C

H

OH

CO

OHThreonine

CO

OH

C

NH

2CH2CH

NH2 C

H

2CH

2

2

NH

NH

Arginine

Anatomy and Physiology I Student Outline – Chemistry of Life

Page 11

c. Polypeptides

ii. Functions

iii. Structural Organization

a. Primary structure b. Secondary Structure c. Tertiary Structure d. Quaternary Structure

v. Denaturation (See handout on Protein)

OH

C C

H

N

H

Glycine

OH

C C

H

N

H

Glycine

3CH

N C

H

H O

C

Alanine

Peptide Bond

3CH

N C

H

H O

C

Alanine

2CH

C

H

OH

N

H O

C

Serine

N

H O

C

3CH

OH

C

H

OH

Threonine

N

H O

C

3CH

OH

C

H

OH

Threonine

N

H O

C

3CH

OH

C

H

OH

Threonine

N

H O

C

3CH

OH

C

H

OH

Threonine

N

H O

C

C

NH

2CH2CH

C

H

2CH

2

2

NH

NH

Arginine

N

H O

C

C

NH

2CH2CH

C

H

2CH

2

2

NH

NH

Arginine

+-