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Jointly sponsored by The School of Medicine ofThe University of North Carolina at Chapel Hill and Charlotte AHEC

Offered atThe William and Ida Friday Center for Continuing Education

Chapel Hill, North Carolina

39TH ANNUALINTERNAL MEDICINECONFERENCE March 18-20, 2015

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Accreditation StatementThis activity has been planned andimplemented in accordance with theaccreditation requirements and policies of theAccreditation Council for Continuing MedicalEducation (ACCME) through the jointprovidership of Carolinas HealthCare System/Charlotte AHEC and The School of Medicine ofThe University of North Carolina at Chapel Hill.The Carolinas HealthCare System/CharlotteAHEC is accredited by the ACCME to providecontinuning medical education for physicians.

Credit Designation Statement The Carolinas HealthCare System/CharlotteAHEC designates this Live Activity for amaximum of 22 AMA PRA Category 1Credit(s)™. Physicians should claim only thecredit commensurate with the extent of theirparticipation in this activity.Wednesday, March 18 – 8.0Thursday, March 19 – 8.25Friday, March 20 – 5.75

The Charlotte Area Health Education Center(AHEC) designates this continuing educationprogram as fulfilling the requirement for 2.2Continuing Education Units (CEUs),representing 22.0 Contact Hours.

Application for CME credit has been filed withthe American Academy of Family Physicians.Determination of credit is pending.

AAFP Credit

Policy on Faculty and SponsorDisclosure The Carolinas HealthCare System/CharlotteAHEC adheres to the ACCME Standardsregarding industry support of continuingmedical education. Disclosure of faculty andcommercial support relationships, if any, willbe made known at the activity.

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Charlotte AHEC and The Department of Medicine of theUniversity of North Carolina at Chapel Hill School of Medicine Present: Conference Location

The conference will be held at the William andIda Friday Center for Continuing Education, (100 Friday Center Drive, Chapel Hill, NC 27599) located approximatelythree miles east of the UNC-Chapel Hillcampus on Friday Center Drive, just off HWY54 East. If you will be traveling I-40, you willneed to take Exit 273-A from Raleigh or 273from Greensboro. Participants may be reachedduring the conference at 919-962-3009.

Although every effort is made to provide acomfortable temperature in the meeting room,it is difficult to find a temperature that iscomfortable for everyone. Please bring a lightjacket or sweater in case the room is too coolfor your comfort.

WiFi access and electrical outlets will beavailable.

RegistrationRegistration will be limited to 400participants due to room capacity. Please seewww.charlotteahec.org regarding availabilityof walk-in registrations.

Seats will be available in the main lecture hall for all registrants. However, a satellite conference room with audio/video feed will also be available for those who prefer more room to spread out, desks, and to sit where food and drink are allowed.

Registration may be by fax, mail, or online. The registration fees include educational credit,course materials, breakfast, lunch, and breaksfor all three days, and the Thursday nightreception. All registrants must complete the attached registration form or the similar formonline at www.charlotteahec.org.

Registrations will not be processed unless accompanied by full payment (check, Visa, MasterCard, Discover or American Express). You may register by 1) faxing your form with credit card information to 704-512-6561, 2) mailing your form with check or credit card information to the address on the registration form, or 3) submitting your registration information online. Checks accompanying registrations should be made payable to Charlotte AHEC.

Online registration is available at www.charlotteahec.org

Target AudienceThis conference is designed for internists,family physicians, generalists, and other healthcare providers working in an adult primarycare setting.

Course Description The 39th Annual Internal Medicine Conferencewill provide an update on the most usefulrecent developments in the diagnosis andmanagement of specific medical disordersencountered by primary care physicians andpracticing specialists.

➲ Spouses and guests are also encouraged toattend the reception at the Friday Center onThursday, March 19, 2015. This receptionwill feature the Musical Classical Trio andhors d’oeuvres!

Conference Features Include➲ Panel discussions organized to address

questions and comments from participantsabout important issues in the practice ofinternal medicine.

➲ A program format which invites interactionbetween faculty and participants.

➲ Participation of faculty and Chiefs fromthe Divisions of the UNC Department ofMedicine.

➲ Mini Symposium on Screening.➲ An interdisciplinary approach to medical

practice. ➲ Optional “Meet the Professor” Discussion

Sessions. Participants will have anopportunity to talk informally with UNCDepartment of Medicine faculty and discussrecent developments within a subspecialty,and specific cases.

➲ Radiology Unknowns – Participants willhave an opportunity to study clinical casesby X-ray and/or narrative description andto make a diagnosis.

➲ Guest faculty from other Universities and Departments at UNC School of Medicine.

AccommodationsPlease contact the hotels directly to make reservations and identify yourself as an attendee at the 39th Annual Internal Medicine Conference. A block of rooms has been reserved at the following hotels:

ALOFT, located 1.2 miles from the Friday Center,at a special rate of $119 + tax per night. Please call 1-800-228-3000 to make your reservation. This room block expires on February 17, 2015.

Courtyard by Marriott, located 0.3 miles from the Friday Center, at a special rate of $127+ tax per night. Please call 1-800-321-2211 or 919-883-0700 to make your reservation. This room block will expire on February 17, 2015.

Sheraton Chapel Hill Hotel, located 4.8 miles from the Friday Center, at a special rate of $111 + tax per night. Please call 1-800-325-3535 or 919-969-2174 to make your reservation. This hotel has a complimentary shuttle service to the Friday Center. This room block expires on February 15, 2015.

Please check the Chapel Hill/Orange CountyVisitor’s Bureau website at http://www.chovb.org for more information on hotels,transportation and restaurants in the area.

Cancellation PolicyIf you cancel more than 2-weeks in advancethere is a $25 cancellation fee. Participants thatare registered for the program and cancelbetween 2 weeks and up to 48 hours prior to theprogram will receive a 70% refund. No refundswill be given for individuals who cancel lessthan 48-hours prior to the program. No transfersor refunds will be given for no-shows. Substitutes are welcome (please notify us inadvance of the program). Cancellations must bemade in writing (fax, mail, or email).

For questions about registration, please go to our website, www.charlotteahec.org, or call Jessica Dietrich, Charlotte AHEC 704-512-6519.When your registration is processed, you will be emailed a confirmation.

The information presented at this educationalactivity should improve your ability to:

Educational Objectives

➲ Discuss the diagnostic procedures for common conditions seen by primary care providers with focus on the sensitivity,

specificity and positive and negativepredictive values of the diagnostic procedureAnalyze different therapeutics for commonconditions seen by primary care cliniciansAssess results of recent clinical trials relevantto health promotion and screening

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REGISTRATION FEES (please mark applicable fee) Registration will be limited to 400 participants due to roomcapacity, therefore, availability for walk-in registration will be dependent on participant numbers. Please seewww.charlotteahec.org regarding availability for walk-in registrations.❑ Total Conference $420.00 ❑ UNC Faculty $75.00/Day ❑ $350.00/Two Day ❑ $200.00/One Day

SPECIAL ACTIVITIY – Thursday, March 19, 2015 ❑ Reception at the Friday Center ______________________ # Attending Reception

Guest Faculty

UNC Department of Medicine Faculty

CONFERENCE DIRECTORRomulo E. Colindres, MD, MSPH - Professor of Medicine,Division of Nephrology & HypertensionCONFERENCE CO–DIRECTORSMarco A. Alemán, MD - Professor of Medicine, Divisionof General Medicine & Clinical EpidemiologyThomas C. Keyserling, MD, MPH - Professor of Medicine,Division of General Medicine & Clinical Epidemiology

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Americans with Disabilities Act: If you need any auxiliary aides or services identified in the Americans with DisabilitiesAct in order to attend this activity, please contact Jessica Dietrich by telephone at 704-512-6519 or by email atjessica.dietrich@carolinashealthcare.org. This request must be received 7 days prior to this activity.

Please Print Legibly

Last Name: ____________________________________ First Name: __________________ MI: _________

Mailing Address: Please check appropriate box: ❑ Home ❑ Business ________________________________________________________________________________________________________________________________________________________________________________________________

City: ______________________________________ State: _________________ Zip Code:

Phone: _________________________________________

E-mail: __________________________________________________________________________________________

Sex: ❑ Male ❑ Female

Degree: Last 4 Digits of Social Security Number: _______________

Employer: Specialty: _______________________________________

Please check all that apply: ❑ Fellow ❑ MD ❑ PhD ❑ NP ❑ PharmD

❑ Other ❑ DO ❑ PA ❑ RN ❑ RPh ❑ Resident

❑ Student

REGISTRATIONPlease complete a separate registration form for each person. Registrations will not be processed unless accompaniedby full payment (check, or credit card). You may register by: • faxing your form, with complete credit card information, to 704-512-6561• completing on-line registration at: www.charlotteahec.org• mailing your form, along with a check or complete credit card information, to:

Charlotte AHEC Registrar PO Box 32861 Charlotte, NC 28232-2861

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WEDNESDAY, MARCH 18, 2015

7:30-8:20 AM Registration and Continental Breakfast8:20-8:30 Welcome and Announcements Romulo E. Colindres, MD, MSPH Conference Director Thomas C. Keyserling, MD, MPH Marco A. Alemán, MD Conference Co-Directors

NEPHROLOGY AND HYPERTENSION

8:30-8:35 Introduction Gerald A. Hladik, MD8:35-9:15 Role of the Primary Care Physician in the Management of Patients with Chronic Kidney Disease Gerald A. Hladik, MD9:15-9:55 Dialysis is not for Everyone: New Data for Deciding with Older Patients Alvin H. Moss, MD9:55-10:15 OPEN PANEL DISCUSSION: Nephrology and Hypertension Audience Participation Gerald A. Hladik, MD Alvin H. Moss, MD10:15-10:30 BREAK

Alvin H. Moss, MD - Professor of Medicine, Sections ofNephrology and Supportive Care; Director, WVU Centerfor Health Ethics and Law, West Virginia UniversityKenneth O’Rourke, MD - Professor of Medicine; Director,Rheumatology Fellowship Training Program,Wake Forest School of MedicineGregg A. Warshaw, MD - Martha Betty SemmonsProfessor of Geriatric Medicine, Geriatric MedicineProgram, College of Medicine, University of Cincinnati

A. Sidney Barritt, IV, MD, MSCR - Assistant Professor of Medicine, Division of Gastroenterology & HepatologyJan Busby-Whitehead, MD - Professor of Medicine; Chief, Division of Geriatric Medicine; Director, Center forAging and HealthJohn B. Buse, MD, PhD, CDE - Verne S. Caviness Distinguished Professor of Medicine; Chief, Division of EndocrinologyShannon S. Carson, MD - Professor of Medicine; Chief, Division of Pulmonary & Critical Care MedicineMyron S. Cohen, MD - Yeargan-Bate Eminent Professorof Medicine, Microbiology, and Immunology; Chief,Division of Infectious Diseases; Associate Vice-Chancellorfor Global Health, UNC Institute for Global Health andInfectious DiseasesJama M. Darling, MD - Assistant Professor of Medicine,Division of Gastroenterology and HepatologyCody S. Deen, MD - Assistant Professor of Medicine,Division of CardiologyJames F. Donohue, MD - Professor of Medicine, Divisionof Pulmonary Diseases & Critical Care MedicineMatthew C. Foster, MD - Assistant Professor of Medicine,Division of Hematology/OncologyElizabeth H. Harris, MD - Assistant Professor of Medicine,Division of EndocrinologyAshley Henderson, MD - Associate Professor of Medicine,Division of Pulmonary Diseases & Critical Care MedicineGerald A. Hladik, MD - Doc. J. Thurston DistinguishedProfessor of Medicine, Division of Nephrology &Hypertension Joanne M. Jordan, MD, MPH - Joseph P. Archie, Jr.Eminent Professor of Medicine; Chief, Division of Rheumatology, Allergy & Immunology; Director, Thurston Arthritis Research CenterDaniel Jonas, MD, MPH - Associate Professor & SectionChief for Research, Division of General Medicine &Clinical Epidemiology; Co-Director, RTI-UNCEvidence-based Practice CenterJonathan Juliano, MD, MPH - Assistant Professor ofMedicine, Division of Infectious Diseases; Director,Anti-Infective Stewardship

Edwin Kim, MD, MS - Assistant Professor of Medicine,Division of Rheumatology, Allergy & ImmunologyRyan D. Madanick, MD - Assistant Professor of Medicine,Division of Gastroenterology & HepatologySarah K. McGill, MD, MSc - Assistant Professor of Medicine,Division of Gastroenterology and HepatologySteven I. Park, MD - Assistant Professor of Medicine,Division of Hematology/OncologyBrandi N. Reeves, MD - Clinical Fellow, Division ofHematology/OncologyDaniel S. Reuland, MD, MPH - Associate Professor ofMedicine, Division of General Medicine & ClinicalEpidemiologyJennifer L. Rogers, MD - Assistant Professor of Medicine,Division of Rheumatology, Allergy & Immunology;Co-Director, Adult Lupus ClinicLisa J. Rose-Jones, MD - Assistant Professor of Medicine,Division of CardiologyJanet Rubin, MD - Professor of Medicine, Division ofEndocrinologyThomas C. Shea, MD - Professor of Medicine, Division ofHematology/Oncology; Director, Bone Marrow TransplantProgramGeorge A. Stouffer, MD - Henry A. Foscue DistinguishedProfessor of Medicine; Chief, Division of Cardiology; Director,Interventional CardiologyStephen L. Tilley, MD - Associate Professory of Medicine,Division of Pulmonary Diseases & Critical Care MedicineDavid van Duin, MD, PhD - Associate Professor of Medicine,Division of Infectious Diseases; Director,Immunocompromised Host SectionJohn P. Vavalle, MD, MHS - Assistant Professor of Medicine,Division of CardiologyPeter M. Voorhees, MD - Associate Professor of Medicine,Division of Hematology/OncologyDavid J. Weber, MD, MPH - Professor of Medicine,Pediatrics, and Epidemiology, Schools of Medicine and PublicHealth; Associate Chief of Staff, UNC Health Care; MedicalDirector, Hospital Epidemiology & Occupational HealthGary S. Winzelberg, MD, MPH - Associate Professor ofMedicine, Division of GeriatricsMichael Yeung, MD - Assistant Professor of Medicine,Division of CardiologyLaura A. Young, MD, PhD - Assistant Professor of Medicine,Division of Endocrinology

Nina M. Browner, MD - Assistant Professor, Departmentof NeurologyPuneet S. Jolly, MD, PhD - Assistant Professor, Departmentof DermatologyKenan Penaskovic, MD - Assistant Professor, Departmentof PsychiatryJoseph M. Stavas, MD - Professor, Department of RadiologyBradley V. Vaughan, MD - Professor, Department ofNeurology

Faculty from other UNC Departments

The 39th Annual Internal Medicine ConferenceMarch 18-20, 2015

Event # 44907

Disclaimer: By providing your email address and telephone number, you have granted permission for AHEC to contact youvia the numbers and address indicated. Would you like your name to be removed from our mailing list? ❑ Yes ❑ No

METHOD OF PAYMENT❑ Check made payable to Charlotte AHEC enclosed ❑ Credit Card (Visa, Mastercard, Discover, AmEx)

Credit Card #: ____ ____ ____ ____ – ____ ____ ____ ____ – ____ ____ ____ ____ – ____ ____ ____ ____

Expiration Date ____ ____ / ____ ____ Signature of Cardholder

Please indicate if you would like a vegetarian meal: ❑ Yes ❑ No

INFECTIOUS DISEASES8:00-8:05 Introductions Myron S. Cohen, MD8:05-8:35 Emerging Infectious Diseases (MERS-CoV, novel influenza viruses, Ebola): Focus on Ebola Preparedness David J. Weber, MD, MPH8:35-9:00 The Growing Threat of Multiple Drug Resistant Organism (MDROs): Do New Anti-Infectives Combat This Threat or Are They Just Me Too Drugs Jonathan Juliano, MD, MPH9:00-9:25 Management of Immunocompromised Patients: Key Issues for Primary Care Providers David van Duin, MD, PhD9:25-9:40 OPEN PANEL DISCUSSION Infectious Diseases Audience Participation Myron S. Cohen, MD, Moderator David van Duin, MD, PhD Jonathan Juliano, MD, MPH David J. Weber, MD, MPH9:40-9:55 BREAK

9:55-10:00 Introduction John B. Buse, MD, PhD10:00-10:20 Diabetes Medication Update John B. Buse, MD, PhD10:20-10:40 Diabetes Technology Update Laura A. Young, MD, PhD10:40-11:00 Diabetes Vignettes from the Wards Elizabeth H. Harris, MD

3:35-3:55 OPEN PANEL DISCUSSION: General Medicine and Clinical Epidemiology Audience Participation Daniel Jonas, MD, MPH, Moderator Thomas C. Keysrling, MD, MPH Daniel S. Reuland, MD, MPH3:55-4:15 BREAK

GASTROENTEROLOGY AND HEPATOLOGY

4:15-4:20 Introduction Ryan D. Madanick, MD4:20-4:40 GERD in the PPI Era: Management Issues in Primary Care Ryan D. Madanick, MD4:40-5:05 Screening for Colorectal Cancer: Will Current Practices Be Changing Soon? Sarah K. McGill, MD, MSc5:05-5:30 Working Through Abnormal Liver Tests: A Rational Approach A. Sidney Barritt IV, MD, MSCR5:30-5:55 Treating Hepatitis C in 2015: The Future has Arrived Jama M. Darling, MD5:55-6:15 OPEN PANEL DISCUSSION: Gastroenterology and Hepatology Audience Participation Ryan D. Madanick, MD Moderator A. Sidney Barritt, IV, MD, MSCR Jama M. Darling, MD Sarah K. McGill, MD, MSc

THURSDAY, MARCH 19, 20157:30-8:00 AM Registration and Continental Breakfast

GERIATRICS1:35-1:40 Introduction Jan Busby-Whitehead, MD1:40-2:20 Alzheimer’s Disease and Related Dementias: Practical Strategies to Address Changing Behavioral Symptoms Gregg A. Warshaw, MD2:20-2:50 Update on Parkinson’s Disease Nina M. Browner, MD2:50-3:15 Update on Code Status: Discussion for the Primary Care Clinician Gary S. Winzelberg, MD, MPH3:15-3:35 OPEN PANEL DISCUSSION: Geriatrics Audience Participation Jan Busby-Whitehead, MD, Moderator Nina M. Browner, MD Gregg A. Warshaw, MD Gary S. Winzelberg, MD, MPH3:35-3:50 BREAK 3:25-3:50 BREAK

11:00-11:20 Osteoporosis Pharmacopeia: Start, Stop or Change? Janet Rubin, MD 11:20-11:45 OPEN PANEL DISCUSSION Endocrinology Audience Participation John B. Buse, MD, PhD, Moderator Elizabeth H. Harris, MD Janet Rubin, MD Laura A. Young, MD, PhD11:45-12:30 Lunch-Trillium Room12:30-1:00 OPTIONAL: “Meet the Professor” Questions and Answer Sessions: Infectious Diseases, Endocrinology, Diabetes, Geriatrics, and Hematology/Oncology (various locations)1:00-1:30 Update on Medical Management of Bipolar Disorder Kenan Penaskovic, MD1:30-1:35 Questions from the Audience

PULMONARY AND CRITICAL CARE MEDICINE

1:00-1:05 Introduction Shannon S. Carson, MD1:05-1:35 COPD: New Approaches and Therapies James F. Donohue, MD1:35-2:05 Asthma: New Therapies and Differentiating Therapy from COPD Stephen L. Tilley, MD2:05-2:35 Pulmonary Rehabilitation: Benefits and selection of patients Ashley Henderson, MD2:35-2:50 OPEN PANEL DISCUSSION: Pulmonary and Critical Care Medicine Audience Participation Shannon S. Carson, MD, Moderator James F. Donohue, MD Ashley Henderson, MD Stephen L. Tilley, MD

2:50 Conference Adjourns until March 30, 2016

10:30-10:35 Introduction Joanne M. Jordan, MD, MPH10:35-11:10 The Shoulder: from Table to Bedside Kenneth O’Rourke, MD11:10-11:30 Update on Angioedema Edwin Kim, MD, MS11:30-11:55 An Approach to Muscle Weakness and Pain Jennifer L. Rogers, MD11:55-l2:15 OPEN PANEL DISCUSSION: Rheumatology, Allergy, and Immunology Audience Participation Joanne M. Jordan, MD, MPH, moderator Edwin Kim, MD, MS Kenneth O’Rourke, MD Jennifer L. Rogers, MD12:15-1:00 LUNCH: Trillium Room1:00-1:30 OPTIONAL: “Meet the Professor” Question and Answer Sessions: Nephrology; Hypertension; Rheumatology, Allergy, and Immunology; General Medicine and Clinical Epidemiology; and Gastroenterology and Hepatology1:30-2:05 The Nusiasance of Snoring, but the Opportunity of a Lifetime: Update on OSA Bradley V. Vaughn, MD2:05-2:10 Questions from the Audience

Mini Symposium on Screening2:10-2:15 Introduction Daniel Jonas, MD, MPH2:15-2:40 Screening, Behavioral Counseling, and Medications for Unhealthy Alcohol use Daniel Jonas, MD, MPH2:40-3:10 Appropriate Implementation of Lung Cancer Screening Guidelines Daniel S. Reuland, MD, MPH3:10-3:35 Should We Screen for Pre-Diabetes? Thomas C. Keyserling, MD, MPH

ENDOCRINOLOGY

HEMATOLOGY/ONCOLOGY3:50-3:55 Introduction Thomas C. Shea, MD3:55-4:20 Management of Indolent Non-Hodgkin Lymphoma Steven I. Park, MD4:20-4:45 Chronic Leukemias: What Generalists Need to Know Matthew C. Foster, MD4:45-5:15 Determining Monoclonal Gammopathies of Clinical Significance Peter M. Voorhees, MD5:15-5:40 Myeloproliferative Neoplasms: Recognition, Diagnosis, and Complications Brandi N. Reeves, MD5:40-6:00 OPEN PANEL DISCUSSION Hematology/ Oncology Audience Participation Thomas C. Shea, MD, Moderator Matthew C. Foster, MD Steven I. Park, MD Brandi N. Reeves, MD Peter M. Voorhees, MD6:00-7:30 Reception and Entertainment with Musical Classical Trio at the Friday Center (Guests Welcome)

FRIDAY, MARCH 20, 2015

CARDIOLOGY8:00-8:05 Introduction George A. Stouffer, MD8:05-8:30 Pulmonary Hypertension: The WHO and What in 2015 Lisa J. Rose-Jones, MD8:30-8:55 The 3 Most Important Cardiovascular Trials from the Last Year for Primary Care Clinicians Cody S. Deen, MD8:55-9:20 Transcatheter Aortic Valve Replacement (TAVR): Where are we now? John P. Vavalle, MD, MHS9:20-9:45 Hypertrophic Obstructive Cardiomyopathy and Alcohol Septal Ablation Michael Yeung, MD9:45-10:05 OPEN PANEL DISCUSSION Cardiology Audience Participation George A. Stouffer, MD, Moderator Cody S. Deen, MD Lisa J. Rose-Jones, MD John P. Vavalle, MD, MHS Michael Yeung, MD10:05-10:20 BREAK

10:20-10:50 Psoriasis: from Bench to Bedside Puneet S. Jolly, MD, PhD10:50-10:55 Questions from the Audience10:55-11:20 Late Breaking Presentation (will address timely medical topic/research findings reported or published in early 2015)11:20-11:25 Questions from the Audience11:25-12:00 LUNCH-Trillium Room12:00-12:30 OPTIONAL: “Meet the Professor” Questions from the Audience Sessions: Cardiology and Pulmonary and Critical Care Medicine (various locations)12:30-1:00 Review of Radiology Unknowns Joseph M. Stavas, MD

7:30-8:00 AM Registration and Continental Breakfast

RHEUMATOLOGY, ALLERGY, AND IMMUNOLOGY

GENERAL MEDICINE & CLINICAL EPIDEMIOLOGY