ch 4: mendel and modern evolutionary theory (ch 3/4) week 4€¦ · ch 4: mendel and modern...
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Ch 4: Mendel and Modern evolutionary theory
Week 4(Ch 3/4)
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-Anthro club
-Social sciences night
-Quiz Thursday, October 4th
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Mendel's principles of inheritance
Synthetic theory of evolution
Homework pass back
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Mendelian principles of inheritanceMendel's principles explains transmission of traits generation to generation
Background: decades of experiments with pea plant hybrids.
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Mendelian principles of inheritance
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Experiments: crossbred pure-bred pea plants
Parent generation:-tall pea plants x short pea plants
F1 generation:
F2 generation:
Mendel's first principle of inheritancePrinciple of segregation: traits are controlled by discrete units which come in pairs and separate into sex cells.
Alleles: variations of a gene at a locus, i.e., allele pairs control trait expression
E.g., pea plant height is controlled by two alleles at one locus
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Mendel's first principle of inheritanceRecessive alleles are masked by the expression of dominant alleles
Homozygous: two copies of an allele
Heterozygous: two different alleles
Genotype: organism's entire genetic makeup
Phenotype: observed physical expression of genotype/genes
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Mendel's second principle of inheritancePrinciple of independent assortment: traits are inherited separately
E.g., pea plant height and seed color are not inherited together
-genes that code for different traits sort out individually during gamete formation
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Punnett square problems1. Identify the different phenotypic and genotypic ratios in F2 generations for a cross of two heterozygous tall plants (tall = dominant trait).
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Punnett square problems2. Hypothetically, B is the allele that causes brachydactyly. If a man with two normal alleles (bb) has average length fingers/toes has kids with a woman with brachydactyly (Bb).
What proportion of their kids will have average length fingers/toes?
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Synthetic theory of evolutionSynthetic theory of evolution
-modern synthesis of Darwin's theory and genetics now:
Evolution defined: change in allele frequencies of a population from one generation to the next.
Gene pool: the genetic material (alleles) making up a population of organisms
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Mendelian geneticsMendelian traits-discrete traits-one gene determines one trait-rarely influenced by environment
Polygenic traits-continuous-multiple genes determine one trait-relationship between genetics/environment heavily influential
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Synthetic theory of evolutionTwo-stages of evolution involve variation and natural selection
Stage 1: Factors produce and redistribute variation
Stage 2: Natural selection acts on variation
Microevolution: changes from generation to generation
Macroevolution: speciation, changes over time evident in the fossil record
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Factors producing and redistributing variation1. Mutations: any change in alleles-produces new alleles (only source of new genetic material)-only passed on if occurs in gametes
2. Recombination: chromosome pairs exchange DNA during meiosis shuffling variation for natural selection to act on
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Factors producing and redistributing variation3. Genetic drift: changes in allele frequencies due to chance
Founder effect: small subpopulation starts new popn
Bottleneck: population shrinks and recoversE.g., Pingelap islanders today are mostly colorblind
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Factors producing and redistributing variation4. Gene flow: (migration) exchange of genes between populationsE.g., significant gene flow between human populations explains the low occurrence of hominin speciation in the past million years
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Variation and natural selectionNatural selection
-directional change relative to environment
-acts on variation
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