case management on tetanus infection

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    P G I K R I S T E L M A G N E Z A R A S P E

    MEASLES

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    General Data

    D.A

    21 years old

    Male

    Single Catholic

    Tabangao, Ambulong, Batangas City

    Admitted on December 15, 2013

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    Chief Complaint

    Rashes

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    History of Present Illness

    1 week PTA

    on and off undocumented fever

    Cough non productive, whitish phlegm

    Colds

    No consult done

    Self medicate with Paracetamol 500mg/tab every 4 hours andIbuprofen

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    5 days PTA

    Loss of appetite

    Post prandial pain

    Throat pain

    Generalized body weakness

    No consult done

    Continue self medication

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    2 days PTA

    Rashes, pruritic

    Cough, productive, yellowish phlegm

    Few hours PTA Rashes progressively spread all over his body

    Difficulty of breathing

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    Past Medical History

    Unrecalled course of immunization

    (-) surgery, accidents and blood tranfusion

    (-) heredofamilial diseases

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    Family History

    (-) HTN, DM

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    Personal and Social History

    Occasional alcoholic drinker

    3-4 sticks/day

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    Review of System

    General: (-) weight loss, (-) weight gain, (-)chill, (-)fatigue, (-) night sweats

    Skin: (-) color change, (-) soreness, (-) scaling

    Head and Neck: (-) headache, (-) stiffness, (-)trauma Eyes: (-) corrective lenses, (-)pain, (-) blurring of

    vision, (-) dryness

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    Ears: (-) hearing loss, (-) pain, (-) tinnutus

    Nose: (-) nasal discharges

    Mouth: (-) bleeding gums, (-) hoarseness, (-) pain,(-) dryness

    Respiratory: (-) cough, (-) chest, (-) dyspnea

    Cardiac: (-) orthopnea, (-) PND, (-) palpitation

    Nervous: (-)dizziness, (-) seizures Extremities: (-) pain, (-) weakness, (-) tenderness,

    (-) cramps

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    Physical Examination

    General Survey: The patient is conscious, coherent,ambulatory, weak looking and not in cardio-respiratory distress.

    Vital signs:BP: 90/60 mmHg

    Cardiac rate: 83beats/minute

    Respiratory Rate: 19 cycles/minute

    Temperature: 38.20C

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    Skin: brown, warm, moist with good skin turgor , (+)maculopapular rashes all over

    HEENT: conjunctival injection, hyperemic sclera, no

    sunken eyeball, dry lips, (+)nasal watery discharge,moist buccal mucosa, no tonsillopharyngealcongestion, no cervicolymphadenopathy, no neck

    vein engorgement, no anterior neck mass, no neck

    bruit

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    CHEST/LUNGS: symmetrical chest expansion, nolagging, no retractions, (+) crackles on midbasal lungfields bilateral

    HEART: Adynamic precordium, point of maximalimpulse is located at the 5thICS left midclavicularline, normal rate and regular rhythm, no murmurs

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    ABDOMEN: flabby abdomen, normoactive bowelsounds , soft, non-tender on light and deep palpation

    EXTREMITIES: grossly normal extremities, nocyanosis and edema with full and equal pulses on

    brachial and radial.

    DRE: not done

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    Neurological Exam

    Cerebral Function: awake, alert, oriented to time,person and place, with intact remote, recentmemory,can do simple calculations, with good

    judgement

    Cerebellar Function: able to perform finger to nosetest, alternating supination and pronation.

    Cranial Nerves: Intact

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    Motor Function: no muscle atrophy, muscle strengthis 5/5 on both upper and lower extremities, notremors noted

    Sensory Function: reacts to pain, touch, position andvibration sense

    Reflexes: (+) deep tendon reflexes

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    Admitting Impression

    Measles

    Community Acquired Pneumonia

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    Admission: ER

    IVF: D5LR 1L x 40 gtts/ min

    Diet: Diet as Tolerated; Increased oral fluid intake

    Diagnostics:

    CBC with PC Urinalysis

    Chest Xray

    Sodium, Potassium

    BUN, Creatinine

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    U/A Color SpecificGravi

    ty

    pH Sugar

    Albumin

    PusCells

    RBC AmorpUrat

    es

    Epithcells

    Bacteria

    Amber

    1.025 6 (-) (-) 2-4 1-2 Moderate

    Few Few

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    Blood Chemistry 12/15/13

    Sodium 121

    Potassium 3.06

    BUN 11.5

    Creatinine 94.8

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    Chest Xray BasalPneumonia,Left

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    Course in the wards

    1stHospital Day S: (+) cough

    Potasium: 3.06

    O: afebrile ; stable vital signs

    A: Measles: Community Acquired Pneumonia

    P: Continue present management

    Start Kalium Durule TID for 2 days

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    2ndHospital Day S: decreased severity of cough

    O: stable vital signs; decreased crackles

    A: Measles; Community Acquired Pneumonia

    P: Continue present management

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    3rdHospital Day S: no subjective complaints

    O: afebrile

    A: Measles; Community Acquired Pneumonia

    P: May go home

    Home Meds:

    Cefixime 200mg/tab BID x 7days

    Azithromycin 500mg/tabs OD x 3 days

    Salbutamol + Ipratropium Bromide neb every 8 hours

    Loratadine 10mg/tab OD as needed

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    Measles

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    Definition

    highly contagious viral disease that is characterizedby a prodromal illness of fever, cough, coryza, andconjunctivitis followed by the appearance of ageneralized maculopapular rash

    The Centers for Disease Control and Prevention :(1)a generalized maculopapular rash of at least 3 days'duration; (2) fever of at least 38.3oC (101oF); and (3)

    cough, coryza, or conjunctivitis.

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    Etiology

    spherical, nonsegmented, single-stranded, negative-sense RNA virus

    Morbillivirus

    family of Paramyxoviridae antigenically monotypic virus

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    Epidemiology

    most highly contagious directly transmittedpathogens

    common among household contacts, school-age

    children, and health care workers Endemic measles has a typical temporal pattern.

    As measles vaccine coverage increases or populationdensity decreases

    Persons with measles are infectious for several daysbefore and after the onset of rash.

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    Pathophysiology

    Transmission Respiratory droplets

    Small-particle aerosols

    Airborne transmission

    Direct contact with infected secretions

    Incubation Period

    10 days to fever onset 14 days to rash onset

    Adults up to 3 weeks

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    Clinical Manifestations

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    Kopliksspots

    pathognomonic ofmeasles

    bluish white dots 1 mm in

    diameter surrounded byerythema

    buccal mucosa oppositethe lower molars but

    rapidly increase innumber to involve theentire buccal mucosa

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    Rash

    erythematous maculesbehind the ears and onthe neck and hairline

    progresses to involve theface, trunk, and armswith involvement of thelegs and feet by the end

    of the second day Areas of confluent rash

    appear on the trunk and

    extremities

    petechiae may be present

    The rash fades slowly -

    usually beginning on thethird or fourth day afteronset

    Resolution of the rash

    may be followed bydesquamation

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    Differential Diagnosis

    Rubella

    Kawasaki disease

    Infectious mononucleosis

    Roseola Scarlet fever

    Rocky Mountain spotted fever

    Enterovirus Adenovirus infection

    Drug sensitivity

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    Laboratory Diagnosis

    Serology

    Culture

    PCR

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    Complications

    Most common Otitis Media

    Bronchopneumonia

    Respiratory Tract Acute laryngotracheobronchitis

    Giant-cell pneumonitis

    Central Nervous System

    Encephalomyelitis Measles inclusion body encephalitis

    Subacute sclerosing panencephalitis

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    Prevention

    Passive Immunization Human immunoglobulin

    within 72 h of exposure - immunocompetent persons

    Administered up to 6 days after exposure

    Prophylaxis - children

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    Active Immunization Mumps and rubella (MMR)

    Mumps, rubella, and varicella (MMR-V)

    first vaccination varies from 6 to 15 months

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    T H A N K Y O U !