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Cardiovascular Disease and Metabolic Syndrome Robert B. Weber, MD, FACC 4340 Overland Avenue Culver City, CA 90230 Phone 310 558-9777 Fax 310 558-9778

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Page 1: Cardiovascular Disease and Metabolic Syndrome...Cardiovascular Disease and Metabolic Syndrome Robert B. Weber, MD, FACC 4340 Overland Avenue Culver City, CA 90230 Phone 310 558-9777

Cardiovascular Diseaseand

Metabolic Syndrome

Robert B. Weber, MD, FACC4340 Overland Avenue

Culver City, CA 90230

Phone 310 558-9777 Fax 310 558-9778

Page 2: Cardiovascular Disease and Metabolic Syndrome...Cardiovascular Disease and Metabolic Syndrome Robert B. Weber, MD, FACC 4340 Overland Avenue Culver City, CA 90230 Phone 310 558-9777

Teaching Objectives of the Presentation:

• Review of the AMA Guides’ 5th Edition impairment tables for cardiovascular impairment rating

• Overview of the heart anatomy

• Understand the basics of how the heart functions

• Overview of the most common Workers’ Compensation cardiovascular claims

• Learn the symptoms and criteria of Metabolic Syndrome

• Treatment Recommendations for Metabolic Syndrome

Page 3: Cardiovascular Disease and Metabolic Syndrome...Cardiovascular Disease and Metabolic Syndrome Robert B. Weber, MD, FACC 4340 Overland Avenue Culver City, CA 90230 Phone 310 558-9777

AMA Guides - Table 3-6a page 36

Page 4: Cardiovascular Disease and Metabolic Syndrome...Cardiovascular Disease and Metabolic Syndrome Robert B. Weber, MD, FACC 4340 Overland Avenue Culver City, CA 90230 Phone 310 558-9777

AMA Guides - Table 3-9 page 47

Page 5: Cardiovascular Disease and Metabolic Syndrome...Cardiovascular Disease and Metabolic Syndrome Robert B. Weber, MD, FACC 4340 Overland Avenue Culver City, CA 90230 Phone 310 558-9777

AMA Guides - Table 3-11 page 56

Page 6: Cardiovascular Disease and Metabolic Syndrome...Cardiovascular Disease and Metabolic Syndrome Robert B. Weber, MD, FACC 4340 Overland Avenue Culver City, CA 90230 Phone 310 558-9777

ANATOMY OF THE HEART

How the heart functions:

Page 7: Cardiovascular Disease and Metabolic Syndrome...Cardiovascular Disease and Metabolic Syndrome Robert B. Weber, MD, FACC 4340 Overland Avenue Culver City, CA 90230 Phone 310 558-9777
Page 8: Cardiovascular Disease and Metabolic Syndrome...Cardiovascular Disease and Metabolic Syndrome Robert B. Weber, MD, FACC 4340 Overland Avenue Culver City, CA 90230 Phone 310 558-9777
Page 9: Cardiovascular Disease and Metabolic Syndrome...Cardiovascular Disease and Metabolic Syndrome Robert B. Weber, MD, FACC 4340 Overland Avenue Culver City, CA 90230 Phone 310 558-9777
Page 10: Cardiovascular Disease and Metabolic Syndrome...Cardiovascular Disease and Metabolic Syndrome Robert B. Weber, MD, FACC 4340 Overland Avenue Culver City, CA 90230 Phone 310 558-9777
Page 11: Cardiovascular Disease and Metabolic Syndrome...Cardiovascular Disease and Metabolic Syndrome Robert B. Weber, MD, FACC 4340 Overland Avenue Culver City, CA 90230 Phone 310 558-9777
Page 12: Cardiovascular Disease and Metabolic Syndrome...Cardiovascular Disease and Metabolic Syndrome Robert B. Weber, MD, FACC 4340 Overland Avenue Culver City, CA 90230 Phone 310 558-9777
Page 13: Cardiovascular Disease and Metabolic Syndrome...Cardiovascular Disease and Metabolic Syndrome Robert B. Weber, MD, FACC 4340 Overland Avenue Culver City, CA 90230 Phone 310 558-9777

Left Ventricular Hypertophy

Page 14: Cardiovascular Disease and Metabolic Syndrome...Cardiovascular Disease and Metabolic Syndrome Robert B. Weber, MD, FACC 4340 Overland Avenue Culver City, CA 90230 Phone 310 558-9777

Left Ventricular Hypertrophy

Page 15: Cardiovascular Disease and Metabolic Syndrome...Cardiovascular Disease and Metabolic Syndrome Robert B. Weber, MD, FACC 4340 Overland Avenue Culver City, CA 90230 Phone 310 558-9777

Diastolic Dysfunction

• Diastolic dysfunction may contribute to the signs and symptoms of heart failure (HF), but quantifying the degree of dysfunction is problematic. Diastolic dysfunction is usually diagnosed clinically by elevated filling pressures that result in HF in the absence of systolic dysfunction or valvular abnormalities.

• Echocardiography with cardiac Doppler is emerging as an accepted tool for the assessment of diastolic function.

Page 16: Cardiovascular Disease and Metabolic Syndrome...Cardiovascular Disease and Metabolic Syndrome Robert B. Weber, MD, FACC 4340 Overland Avenue Culver City, CA 90230 Phone 310 558-9777

Table 4-2 page 66 Hypertensive Cardiovascular DiseaseTable 4-2 Criteria for Rating Permanent Impairment Due to Hypertensive Cardiovascular Disease Class 1

0% – 9% Impairment of

the Whole Person

Asymptomatic; stage 1 or

2 hypertension without

medications

or

Normal blood pressure

on anti-hypertensive

medication

and

no evidence of

end-organ damage

Class 2

10% - 29% Impairment

of the Whole Person

Asymptomatic; stage 1 or

2 hypertension despite

multiple medications

or

antihypertensive

medication with any of

the following: (1)

proteinuria, urinary

sediment abnormalities,

no renal function

impairment as measured

by the blood urea

nitrogen (BUN) and

serum creatinine; (2)

definite hypertensive

changes on funduscopic

examination in arterioles,

eg, “copper” or “silver

wiring,” or arteriovenous

crossing changes with

our without hemorrhages

and exudates; either

abnormality suggests

end-organ damage

Class 3

30% - 49% Impairment

of the Whole Person

Asymptomatic; stage 3

hypertension despite

multiple medications

or

antihypertensive

medication with any of

the following: (1)

proteinuria, urinary

sediment abnormalities,

renal function impairment

as measured by the BUN

and serum creatinine,

and a decreased

creatinine clearance of

20% - 50% normal; (2)

LV hypertrophy by ECG

or echocardiography but

no symptoms of HF;

either abnormality

suggests more extensive

end-organ damage

Class 4

50% - 100% Impairment

of the Whole Person

Antihypertensive

medication with stages

1 - 3 and any of the

following abnormalities:

(1) proteinuria, urinary

sediment abnormalities,

renal function impairment

as measured by the BUN

and serum creatinine,

and a creatinine

clearance <20% normal;

(2) hypertensive

cerebrovascular damage

or episodic hypertensive

encephalopathy; (3) LV

hypertrophy, systolic

dysfunction, and/or signs

and symptoms of HF due

to hypertension

Page 17: Cardiovascular Disease and Metabolic Syndrome...Cardiovascular Disease and Metabolic Syndrome Robert B. Weber, MD, FACC 4340 Overland Avenue Culver City, CA 90230 Phone 310 558-9777
Page 18: Cardiovascular Disease and Metabolic Syndrome...Cardiovascular Disease and Metabolic Syndrome Robert B. Weber, MD, FACC 4340 Overland Avenue Culver City, CA 90230 Phone 310 558-9777
Page 19: Cardiovascular Disease and Metabolic Syndrome...Cardiovascular Disease and Metabolic Syndrome Robert B. Weber, MD, FACC 4340 Overland Avenue Culver City, CA 90230 Phone 310 558-9777
Page 20: Cardiovascular Disease and Metabolic Syndrome...Cardiovascular Disease and Metabolic Syndrome Robert B. Weber, MD, FACC 4340 Overland Avenue Culver City, CA 90230 Phone 310 558-9777
Page 21: Cardiovascular Disease and Metabolic Syndrome...Cardiovascular Disease and Metabolic Syndrome Robert B. Weber, MD, FACC 4340 Overland Avenue Culver City, CA 90230 Phone 310 558-9777
Page 22: Cardiovascular Disease and Metabolic Syndrome...Cardiovascular Disease and Metabolic Syndrome Robert B. Weber, MD, FACC 4340 Overland Avenue Culver City, CA 90230 Phone 310 558-9777

COMMON DIAGNOSES IN WORKERS’ COMPENSATION

• Coronary Artery Disease• Clinical Consequences

• Angina (Chest Pain/Pressure)• Myocardial Infarction (Heart Attack)• Sudden Cardiac Death• Ischemic Cardiomyopathy

• Hypertensive Heart Disease• Congestive Heart Failure

Page 23: Cardiovascular Disease and Metabolic Syndrome...Cardiovascular Disease and Metabolic Syndrome Robert B. Weber, MD, FACC 4340 Overland Avenue Culver City, CA 90230 Phone 310 558-9777

DIAGNOSES LESS COMMONLY FOUND IN WORKERS’ COMPENSATION

• Cardiomyopathy• Hypertrophic Cardiomyopathy• Dilated Cardiomyopathy

• Arrhythmias• Atrial premature complexes• Ventricular premature complexes• Atrial Fibrillation• Recurrent (Paroxysmal Ventricular

Tachycardia)

Page 24: Cardiovascular Disease and Metabolic Syndrome...Cardiovascular Disease and Metabolic Syndrome Robert B. Weber, MD, FACC 4340 Overland Avenue Culver City, CA 90230 Phone 310 558-9777

Table 3-6a page 36

Page 25: Cardiovascular Disease and Metabolic Syndrome...Cardiovascular Disease and Metabolic Syndrome Robert B. Weber, MD, FACC 4340 Overland Avenue Culver City, CA 90230 Phone 310 558-9777

AMA Guides – 3.4 Congenital Heart Disease – page 42

• Recently surgical procedures designed to correct or improve the circulation of infants and children with congenital cardiac disorders have allowed many of the children to live to adulthood. Many of these surgically treated patients continue to have less than normal functioning of the heart and circulation and are therefore impaired.

• Congenital heart disease may be recognized by medical history and physical examination, but often the exact diagnosis and the individual’s functional impairment require special studies, including ECG, chest roentgenogram, radioisotope studies, echocardiography, hemodynamic measurements, and angiography.

Page 26: Cardiovascular Disease and Metabolic Syndrome...Cardiovascular Disease and Metabolic Syndrome Robert B. Weber, MD, FACC 4340 Overland Avenue Culver City, CA 90230 Phone 310 558-9777

Activities of Daily Living and Impact on Impairment Rating for Cardiovascular Disease

Page 27: Cardiovascular Disease and Metabolic Syndrome...Cardiovascular Disease and Metabolic Syndrome Robert B. Weber, MD, FACC 4340 Overland Avenue Culver City, CA 90230 Phone 310 558-9777

ACTIVITIES OF DAILY LIVING Table 1-2 page 4

Activity Example

Self-care, personal hygiene Urinating, defecating, brushing teeth, combing hair, bathing, dressing oneself, eating

Communication Writing, typing, seeing, hearing, speaking

Physical activity Standing, sitting, reclining, walking, climbing stairs

Sensory function Hearing, seeing, tactile feeling, tasting, smelling

Nonspecialized hand activities Grasping, lifting, tactile discrimination

Travel Riding, driving, flying

Sexual function Orgasm, ejaculation, lubrication, erection

Sleep Restful, nocturnal sleep pattern

Page 28: Cardiovascular Disease and Metabolic Syndrome...Cardiovascular Disease and Metabolic Syndrome Robert B. Weber, MD, FACC 4340 Overland Avenue Culver City, CA 90230 Phone 310 558-9777

Metabolic Syndrome

Page 29: Cardiovascular Disease and Metabolic Syndrome...Cardiovascular Disease and Metabolic Syndrome Robert B. Weber, MD, FACC 4340 Overland Avenue Culver City, CA 90230 Phone 310 558-9777
Page 30: Cardiovascular Disease and Metabolic Syndrome...Cardiovascular Disease and Metabolic Syndrome Robert B. Weber, MD, FACC 4340 Overland Avenue Culver City, CA 90230 Phone 310 558-9777

Criterion Definition

Abdominal Obesity Waist CircumferenceMen > 40 in. (>102 cm)Women > 35 in. (>88 cm)

Hypertriglyceridemia >150 mg/dL

Low HDL-C Men, <40 mg/dLWomen, <50 mg/dL

High blood pressure >130/85 mmHg

High fasting glucose >110 mg/dL

Diagnostic Criteria for Metabolic Syndrome *

*Diagnosis based on presence of three of five factors.Source: Reference 6

Page 31: Cardiovascular Disease and Metabolic Syndrome...Cardiovascular Disease and Metabolic Syndrome Robert B. Weber, MD, FACC 4340 Overland Avenue Culver City, CA 90230 Phone 310 558-9777

Metabolic Syndrome

• Criteria:

• Need 3 of 5 factors to diagnose the

condition

• Increasingly recognized that these physical

findings and laboratory abnormalities in

combination represent a condition called

“Metabolic Syndrome”.

• This syndrome is associated with an

increased risk for cardiovascular disease.

Page 32: Cardiovascular Disease and Metabolic Syndrome...Cardiovascular Disease and Metabolic Syndrome Robert B. Weber, MD, FACC 4340 Overland Avenue Culver City, CA 90230 Phone 310 558-9777

Sleep Deprivation

• Diagnosis of Sleep Apnea

• Insomnia

• Can have multiple causes

• Interference of Pain

• Medication side effects

• Emotional etiologies

Page 33: Cardiovascular Disease and Metabolic Syndrome...Cardiovascular Disease and Metabolic Syndrome Robert B. Weber, MD, FACC 4340 Overland Avenue Culver City, CA 90230 Phone 310 558-9777

The Influence of Sex Hormones on Cardiovascular Health and Metabolism

Recent research on effects of hormonal imbalance

Page 34: Cardiovascular Disease and Metabolic Syndrome...Cardiovascular Disease and Metabolic Syndrome Robert B. Weber, MD, FACC 4340 Overland Avenue Culver City, CA 90230 Phone 310 558-9777
Page 35: Cardiovascular Disease and Metabolic Syndrome...Cardiovascular Disease and Metabolic Syndrome Robert B. Weber, MD, FACC 4340 Overland Avenue Culver City, CA 90230 Phone 310 558-9777
Page 36: Cardiovascular Disease and Metabolic Syndrome...Cardiovascular Disease and Metabolic Syndrome Robert B. Weber, MD, FACC 4340 Overland Avenue Culver City, CA 90230 Phone 310 558-9777

How to Manage a Claim File for an Injured Worker Diagnosed with Metabolic Syndrome:

• Important considerations to value when manage

a claim with the diagnosis of Metabolic Syndrome

• Diagnostic Studies

• Nutritional counseling

• Exercise

• Swimming

• Walking

Page 37: Cardiovascular Disease and Metabolic Syndrome...Cardiovascular Disease and Metabolic Syndrome Robert B. Weber, MD, FACC 4340 Overland Avenue Culver City, CA 90230 Phone 310 558-9777
Page 38: Cardiovascular Disease and Metabolic Syndrome...Cardiovascular Disease and Metabolic Syndrome Robert B. Weber, MD, FACC 4340 Overland Avenue Culver City, CA 90230 Phone 310 558-9777

IN SUMMARY………• The take home point of my lecture today:

• Metabolic Syndrome in the general population comes about due to factors that are considered non-industrial, but can also be found in the injured worker population due to factors which are considered non-industrial, as well as increasingly due to consequences of an industrial injury.

• The conditions making up metabolic syndrome, individually and in combination, increase the risk of cardiovascular disease.