Cardiac Arrhythmias Caused Cardiac Arrhythmias Caused by Sleep Deprivation due to by Sleep Deprivation due to

Obstructive Sleep ApneaObstructive Sleep Apnea

John P. Cemonuk, Jr., R.T. (R)(MR)John P. Cemonuk, Jr., R.T. (R)(MR)

April 25, 2009April 25, 2009

ProblemProblem

1.1. Obstructive Sleep Apnea (OSA) effects 1 Obstructive Sleep Apnea (OSA) effects 1 in 4 men and 1 in 10 womenin 4 men and 1 in 10 women

2.2. OSA causes sleep deprivation and sleep OSA causes sleep deprivation and sleep fragmentationfragmentation

3.3. OSA is thought to predispose to cardiac OSA is thought to predispose to cardiac arrhythmias arrhythmias

? Research Question ?? Research Question ?

Are people who suffer from Are people who suffer from chronic sleep deprivation chronic sleep deprivation more prone to having more prone to having cardiac arrhythmias than cardiac arrhythmias than those who do not? those who do not?

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MethodologyMethodology Patients (aged 35-50) referred for polysomnography over a 4 week Patients (aged 35-50) referred for polysomnography over a 4 week

period were selected for studyperiod were selected for study After initial sleep study, patients were separated into 2 groups, After initial sleep study, patients were separated into 2 groups,

normal patients and patients with sleep apneanormal patients and patients with sleep apnea Normal patients received second study without treatmentNormal patients received second study without treatment Sleep Apnea patients received second study with CPAP treatmentSleep Apnea patients received second study with CPAP treatment All patients sleep studies were scored and ECG studied for All patients sleep studies were scored and ECG studied for

pathologically significant arrhythmias (AV Block, ventricular pathologically significant arrhythmias (AV Block, ventricular tachycardia, complex ventricular ectopy) tachycardia, complex ventricular ectopy)

Patients with pacemakers, defibrillators, a recent history of Patients with pacemakers, defibrillators, a recent history of myocardial infarction, or cardiac surgery were excluded as well as myocardial infarction, or cardiac surgery were excluded as well as those taking those taking ββ-blockers-blockers

Results of normal and abnormal sleep studies were compared to Results of normal and abnormal sleep studies were compared to determine if people with OSA, and therefore chronic sleep determine if people with OSA, and therefore chronic sleep deprivation, have more arrhythmias than those who do not have deprivation, have more arrhythmias than those who do not have OSAOSA