Carbaryl(1-naphthyl methylcarbamate)

DIETARY RISK CHARACTERIZATION DOCUMENT

Medical Toxicology BranchDepartment of Pesticide Regulation

California Environmental Protection Agency

May 13, 2010

O C

O

NH CH3

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CONTRIBUTORS AND ACKNOWLEDGEMENTS

Author: Andrew L. Rubin, Ph.D., D.A.B.T.Staff ToxicologistHazard Assessment GroupMedical Toxicology Branch, DPR

Toxicology reviews: Joyce Gee, Ph.D., Harry Green, Thomas Kellner, Ph.D.,D.A.B.T., Jim Kishiyama, Fred Martz, Ph.D., Charles Miller,Ph.D., Thomas Moore, Ph.D. and Jay Schreider, Ph.D.Medical Toxicology Branch, DPR

Peer reviews: Joyce Gee, Ph.D.Senior ToxicologistHazard Assessment GroupMedical Toxicology Branch, DPR

Nu-may R. Reed, Ph.D., D.A.B.T.StaffToxicologistHazard Assessment GroupMedical Toxicology Branch, DPR

Jay Schreider, Ph.D.Primary State ToxicologistMedical Toxicology Branch, DPR

The author also thanks Wes Carr and Dr. Eric Kwok (Medical Toxicology Branch, DPR) for theirexpertise and advice in interpreting the carbaryl dietary residue database and Drs. Eric Kwokand Svetlana Koshlukova (Medical Toxicology Branch, DPR) for their help in interpreting theacute Functional Observational Battery data.

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TABLE OF CONTENTS

I. SUMMARY . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1

II. INTRODUCTION . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 11A. CHEMICAL IDENTIFICATION . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 11B. REGULATORY HISTORY . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 12C. TECHNICAL AND PRODUCT FORMULATIONS . . . . . . . . . . . . . . . . . . . . . . . 13D. USAGE . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 14E. ILLNESS REPORTS . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 16F. PHYSICO-CHEMICAL AND ENVIRONMENTAL PROPERTIES . . . . . . . . . . . 18G. ENVIRONMENTAL FATE . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 19

III. TOXICOLOGY PROFILE . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 20A. PHARMACOKINETICS . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 20

1. Overview . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 202. Pharmacokinetics in laboratory animals . . . . . . . . . . . . . . . . . . . . . . . . 20

B. ACUTE TOXICITY (including ACUTE NEUROTOXICITY) . . . . . . . . . . . . . . . . 311. Overview . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 312. Human exposures . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 323. Laboratory animal studies . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 35

C. SUBCHRONIC TOXICITY (including NEUROTOXICITY) . . . . . . . . . . . . . . . . 461. Overview . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 462. Laboratory animal studies . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 47

a. Oral exposure . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 47b. Dermal exposure . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 49

D. CHRONIC TOXICITY AND ONCOGENICITY . . . . . . . . . . . . . . . . . . . . . . . . . 531. Overview . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 532. Laboratory animal studies . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 53

E. GENOTOXICITY . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 751. Overview . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 752. Gene mutation . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 753. Chromosomal aberrations . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 764. DNA damage . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 785. Formation and genotoxicity / carcinogenicity of nitrosocarbaryl . . . . . . 80

F. REPRODUCTIVE TOXICITY . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 841. Overview . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 842. Human epidemiologic studies . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 843. Laboratory animal studies . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 89

a. Contract laboratory studies . . . . . . . . . . . . . . . . . . . . . . . . . . . . 89b. Studies from the open literature - oral gavage exposure . . . . . . 91c. Studies from the open literature - dietary or intraperitoneal

exposure . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 96G. DEVELOPMENTAL TOXICITY . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 100

1. Overview . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1002. Laboratory animal studies . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 100

a. Rats - gavage . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 100b. Rabbits and mice - gavage . . . . . . . . . . . . . . . . . . . . . . . . . . . 100c. Dogs - dietary . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 103

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H. DEVELOPMENTAL NEUROTOXICITY . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 108I. TOXICITY OF THE CARBARYL DEGRADATES AND METABOLITES . . . . . 114

1. 1-Naphthol . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1142. Methylamine . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 118

IV. RISK ASSESSMENT . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 120A. HAZARD IDENTIFICATION . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 120

1. Non-oncogenic effects . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 120a. Acute oral toxicity . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 120b. Chronic oral toxicity . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 122c. Reproductive and developmental toxicity . . . . . . . . . . . . . . . . 123d. Genotoxicity . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 124

2. Oncogenicity . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 124B. DIETARY EXPOSURE ASSESSMENT . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 128

1. Introduction . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1282. Consumption data and dietary exposure . . . . . . . . . . . . . . . . . . . . . . 1283. Exposure to carbaryl and 1-naphthol in food . . . . . . . . . . . . . . . . . . . 1294. Residue data sources . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1305. Acute exposure . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1326. Chronic exposure . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 135

C. RISK CHARACTERIZATION . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1521. Acute risk estimation - deterministic and distributional approaches . . 1522. Chronic risk estimation . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1523. Oncogenic risk estimation . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 153

V. RISK APPRAISAL . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 156A. HAZARD IDENTIFICATION . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 156

1. Non-oncogenic effects . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 156a. Acute oral toxicity . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 156b. Chronic oral toxicity . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 158c. Reproductive and developmental toxicity . . . . . . . . . . . . . . . . 158d. Genotoxicity . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 162

2. Oncogenicity . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 162B. DIETARY EXPOSURE ASSESSMENT . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 164

1. Parameter uncertainty . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1642. Model uncertainty . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 165

C. RISK CHARACTERIZATION . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1671. Non-oncogenic risk . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1672. Oncogenic risk . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 168

D. CRITICAL TOXICITY ENDPOINTS AND RISK CALCULATIONS - USEPA vs.DPR . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 169

VI. ISSUES RELATED TO THE FOOD QUALITY PROTECTION ACT . . . . . . . . . . . . . . . . 172

VII. REFERENCE DOSES (RfDs) . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 172

VIII. TOLERANCE ASSESSMENT . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 175A. ACUTE EXPOSURE . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 175B. CHRONIC EXPOSURE . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 180

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IX. CONCLUSIONS . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 181

X. REFERENCES . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 184

Appendix I. Benchmark dose extrapolation for induction of slight hypotonic gait in pregnantSprague-Dawley rats (Robinson and Broxup, 1997) . . . . . . . . . . . . . . . . . . . . . . . . . 195

Appendix II. Benchmark dose extrapolation for brain cholinesterase inhibition in female dogsafter 52 weeks of exposure to dietary carbaryl (Hamada, 1987) . . . . . . . . . . . . . . . . 198

Appendix III. Benchmark dose extrapolation for hemangiosarcoma / hemangioma data in malemice (Hamada, 1993b) . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 202

Appendix IV. Benchmark dose extrapolation for brain cholinesterase inhibition data in femalerats following acute inhalation exposure (Weinberg, 2008) . . . . . . . . . . . . . . . . . . . . 205

Appendix V. DEEM-FCID® Acute Dietary Exposure Assessment and Risk Calculations - PointEstimate (Tier 2) and Monte Carlo (Tier 3) . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 210V-1. Acute Residue Levels - Point Estimate and Monte Carlos Approaches . . . . . . 210V-2. Acute Dietary Exposures and Risk Estimates - Point Estimate Approach . . . . 224V-3. Acute Dietary Critical Exposure Contribution Analysis - Point Estimate Approach

. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 243V-4. Acute Dietary Exposures and Risk Estimates - Monte Carlo Approach . . . . . . . 305V-5. Acute Dietary Critical Exposure Contribution Analysis - Monte Carlo Approach

. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 324

Appendix VI. Residue Data Files (RDFs) for the Acute Monte Carlo Analysis . . . . . . . . . . . 439

Appendix VII. DEEM-FCID® Chronic and Oncogenic Dietary Exposure Assessment and RiskCalculations . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 452VII-1. Chronic Residue Levels . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 452VII-2. Chronic Dietary Exposures and Risk Estimates . . . . . . . . . . . . . . . . . . . . . . . . 460VII-3. Chronic Critical Commodity Contribution Analysis . . . . . . . . . . . . . . . . . . . . . . 461VII-4. Oncogenic Dietary Exposures and Risk Estimates . . . . . . . . . . . . . . . . . . . . . 481

Appendix VIII. The Environmental Fate of Carbaryl (EM Documents by Amrith Gunasekara andby Sue Xu) . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 482

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I. SUMMARY

Carbaryl (1-naphthyl N-methylcarbamate; MW, 201.22) is a broad spectrum insecticide, withadditional registered uses as a molluscicide. It is effective both after ingestion by the targetedpest or after absorption following direct bodily contact. As a member of the carbamate class ofpesticides, carbaryl action is based on its ability to inhibit acetylcholinesterase (AChE) in thecentral and peripheral nervous systems of the target species. Its toxicity in mammalian systemsis also based on this property, though the involvement of other toxic mechanisms is not ruledout.

Plant systems upon which carbaryl is used include citrus and other fruits, vegetables, forage,forests, field crops, nuts, ornamentals, rangeland, turf and shade trees. In addition, there aresignificant residential lawn, garden and pet uses. Carbaryl formulations include aqueousdispersions, baits, dusts, emulsifiable concentrates, flowables, granules, soluble concentrates,suspension concentrates, wettable powders, water dispersible granules and impregnatedmaterials.

Originally manufactured by Union Carbide and now by Bayer Crop Science, carbaryl was firstregistered for use on cotton in the United States in 1959. More than 60 federal food tolerancesare now in effect for this chemical. As of October 2009 there were 47 formulations containingcarbaryl registered in California, with concentrations ranging between 0.126% and 99%. Severalof these formulations also contain metaldehyde.

Illness and injury reportsCarbaryl alone. From 1992-2007 there were 38 illness reports classified as definitely,probably, or possibly associated with the exposure to carbaryl in California, an average of about2 illnesses per year. Among the symptoms reported were systemic illnesses, (includingrespiratory illnesses), skin injuries, and eye injuries. Individuals involved in the handlingprocess (applicators, mixer/loaders, flaggers) reported 11 illnesses and injuries. Sixteen of the38 illnesses/injuries resulted from agricultural carbaryl applications. There were 14 days ofdisability and no hospitalizations resulting from agricultural carbaryl use. For non-agriculturaluse scenarios there were 30 days of disability (of which 18 days are suicide-associated) and 26days of hospitalization (23 days are suicide-associated).

Carbaryl in combination. From 1992-2007, there were 60 illnesses classified as definitely,probably, or possibly associated with exposure to carbaryl used in combination with otherpesticides in California. For the 16-year period, this averages to 4 illnesses per year. The largernumber of illnesses when carbaryl is in combination with other pesticides may be a reflection ofthe toxicity of the other pesticides in the mixture, or it may be that carbaryl is used more oftenwith other pesticides than alone. Forty-eight of the 60 cases resulted from agricultural activities.Among the 48 cases, 16 illnesses and injuries occurred during the handling process (applicator,mixer/loader, flagger). There were 52 days of disability and no days of hospitalization resultingfrom agricultural uses. For non-agricultural uses there were 6 days of disability and nohospitalization reported.

Environmental fateDespite a low vapor pressure and low Henry's Law constant, carbaryl has been detected in theair, both at application sites and remotely to such sites. Association with water droplets orparticulates may play a role in this process. Hydrolysis, which is favored at pH 7 and above, and

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photolysis both occur under aqueous conditions. The presence of microorganisms is expectedto enhance hydrolytic degradation. 1-naphthol, methylamine and CO2 were identified ashydrolytic breakdown products. The major photolysis product is 1-naphthol, which photooxidizesto 2-hydroxy-1,4-naphtho-quinone under basic conditions. Though relatively insoluble in water,carbaryl has been detected in both surface water and groundwater. Hydrolysis, photolysis andmicroorganism-mediated degradation also occur in soil, where, interestingly, breakdown isenhanced under acidic conditions. Carbaryl has a moderate ability to bind to soil, a processwhich is also favored under acidic conditions. Mud has been shown to enhance the removal ofcarbaryl from aqueous systems, presumably by preferential binding. Carbaryl tends to beassociated with the top 0 - 0.15 meters of soil, showing a dissipation half-life of 0.76 - 10.9 days.Exchangeable cations such as potassium enhance the adsorption of carbaryl to soils, a processthat is also enhanced by the presence of organic matter. Carbaryl and its major metabolite, 1-naphthol, are toxic to some beneficial soil-dwelling microorganisms, despite the fact that somebacterial species and at least one fungus can metabolize carbaryl. Microbial degradation ofcarbaryl is enhanced under anaerobic conditions. Carbaryl is toxic to fish, aquatic invertebratesand non-target insects (eg., honeybees), but relatively non-toxic to birds. Metabolism of carbarylin plants is similar to that in animal systems (see below).

PharmacokineticsOrally administered carbaryl is excreted primarily through the urine in rats during the first 24hours, though substantial residues appear in feces and in exhaled air as CO2 (detectable whencarbaryl is labeled in the carbonyl or N-methyl carbon, but not when labeled in the naphthalenering). Metabolites were conjugated with sulfate or glucuronic acid. For animals receiving 1mg/kg, about half the dose was detected in the urine during the first 6 hr, with 80-90% by 24 hrand only slightly more by 168 hr. For animals receiving 50 mg/kg, urinary excretion was slower:12-20% by 6 hr, 64%-69% by 24 hr, and 78-81% by 168 hr. Fecal excretion was also significant,though it comprised a lesser proportion of the administered dose than urinary excretion; by 168hr, 6%-13% of the dose appeared in the feces. A separate study in rats examined theappearance and disappearance of [naphthyl-1-14C]-carbaryl in the blood and other tissues afterexposure by the oral (1.08 or 8.45 mg/kg), dermal (17.25 or 102.95 mg/kg) and intravenous(0.80 or 9.20 mg/kg) routes. Peak levels of radioactivity were detected in the blood at 15 and 30min for the low and high dose oral treatments, respectively; at 4 and 12 hr for the dermalapplications; and were already maximal by the first time point (5 min) for the iv injections. Oraldosing: by 24 hr, radioactivity levels had decreased to 0.81%-2.4% of peak levels in bloodfractions (both doses), 0.60%-2.4% in brain (both doses), 0.67% in liver (high dose only) and0.32% in fat (high dose only). Dermal dosing: by 24 hr, radioactivity levels had decreased to15.9%-25.8% of peak levels in blood fractions (both doses), 27.1%-30.6% in brain (both doses),24.4% in liver (high dose only) and 15.6% in fat (high dose only). Iv dosing: by 24 hr,radioactivity levels had decreased to 4.6%-10.5% in blood fractions (both doses), 1.1%-1.3% inbrain (both doses), 5.7% in liver (high dose only) and 0.72% in fat (high dose only).

The recovery kinetics in other laboratory species examined (guinea pig, sheep) appearedgenerally similar to those in the rat, though there were problems with the latter studies, whichwere conducted during the 1960s, tested few animals and left large fractions of theadministered dose unanalyzed. A possible exception to the rat model was the dog, whereapproximately equal fractions were excreted in the 24-hr urine and feces, though these data,also collected in the 1960s by the same lab, had similar problems. Speculation about thetendency toward tumor formation at high doses in the more recent mouse study centered on ashift in the urinary metabolite pattern at 8000 ppm, with increases in compounds derived from

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epoxide intermediates.

Three major metabolic pathways, presumably predominantly hepatic, were identified in the rat: (1) arene oxide-mediated hydroxylation and subsequent conjugation, (2) hydrolyticdecarbamylation to form 1-naphthol and subsequent conjugation, and (3) oxidation of the N-methyl moiety. Three urinary metabolites found in rat urine - 1-naphthyl glucuronide, 1-naphthylsulfate and 4-(methyl-carbamoyloxy)-1-naphthyl glucuronide - were not found in dog urine. Inaddition, very few hydrolytic products were found in the urine of a single dosed monkey. Thetoxicologic significance of these apparent metabolic species differences was not clear. Humansdo appear to have the ability to decarbamylate carbaryl since carbaryl factory workers wereshown to excrete 1-naphthyl glucuronide and 1-naphthyl sulfate, leading to speculation thathumans are more similar to rats in their pharmacokinetic handling of carbaryl. However, anotherstudy showed that intentionally dosed humans excreted only 25-30% of the carbaryl in the urineat 24 hours, suggesting that the fate of a significant fraction of the dose was unknown.

Hazard identificationAcute oral toxicity. The acute toxicity of carbaryl results from its ability to carbamylate, thusinhibit, acetyl cholinesterase (AChE) at synapses and neuromuscular junctions. Consequentlocal accumulations of acetylcholine (ACh) generate cholinergic effects. Due to the reversibilityof the carbamate-AChE bond, recovery is expected when exposures are low.

Rats exhibited acute oral LD50s between 233 and 840 mg/kg, while mice were between 108 and650 mg/kg. Two critical acute oral regulatory values were established in this assessmentrepresenting endpoints of stronger (#1 below) or weaker (#2 below) experimental support. (1) Acritical acute NOEL of 1 mg/kg was based on the appearance both of clear, statisticallysignificant cholinergic signs (slight tremors, slight hypotonic gait, slight ataxic gait and pinpointpupils) detected in FOB testing and of statistically significant body weight gain decrements inpregnant rats at a gavage dose 10 mg/kg. Despite daily dosing between gestation day 6 andpost partum day 10, the cholinergic signs were first noted on day 6, qualifying them as acuteresponses. The decrease in body weight gain was also acute or near-acute, as the deficit wasapparent by the first weight measurement on gestation day 9, three days after thecommencement of dosing on day 6. Statistically lowered RBC and brain cholinesteraseactivities were also measured at 10 mg/kg, though it is not known if these effects were acute orrequired several daily exposures. However, it is worth noting that the RBC ChE was suppressedby almost 20% on gestation day 6. (2) A critical acute LED10 of 0.25 mg/kg was based onbenchmark dose modeling of the incidence of slight hypotonic gait in pregnant rats in the samegavage study over the study dose range of 0.1 - 10 mg/kg. While this was a developmentalneurotoxicity study in which the dams were exposed between gestation day 6 and post partumday 10 inclusive, the acute nature of this sign was highly probable.

Three acute toxicity studies conducted in a single laboratory established low dose acute LOELsat 10 mg/kg in the rat, similar to the level at which there were overt clinical signs, body weightgain deficits and suppressed cholinesterase activities in the critical study, thus supporting itsobservations. In addition, USEPA established an LED10 of 1.1 mg/kg based on inhibition of braincholinesterase activity in postnatal day 11 rats following a single gavage exposure to carbaryl.

Chronic oral toxicity. The critical chronic oral LOEL was based on 14% inhibition of braincholinesterase activity at the low dose of 3.4 mg/kg/day (p>0.05) in males at 52 weeks in the 1-yr dog dietary study (20% in females at 3.7 mg/kg/day, p<0.05). RBC cholinesterase showed

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statistically significant inhibition at the mid and high doses (11.0-% / 11.2-& mg/kg/day and 33.8-% / 34.4-& mg/kg/day, respectively) at all treatment intervals (weeks 5, 13, 26 and 52), whilenon-statistically significant inhibition was detected at the low dose (up to 14% in males at week13 and 13% in females at week 5, the first measurement). Plasma cholinesterase activites werestatistically suppressed in females at all doses for weeks 5, 13 and 26 (up to 23% at the lowdose). Statistical significance in males occurred at the mid and high doses only.

The benchmark dose approach was employed to estimate a regulatory chronic LED10 value.The Hill algorithm for continuous data generated the most appropriate curve to fit the femaleWeek 52 brain cholinesterase data. The 10% benchmark response rate was chosen inrecognition of the fact that neither overt clinical signs nor histopathology were observedthroughout the study, even at the high dose of ~34 mg/kg/day. The critical chronic LED10 forbrain cholinesterase inhibition in females using the Hill algorithm was 0.5 mg/kg/day (ED10 = 1.7mg/kg/day). This value was used to evaluate the non-oncogenic risks from annual (i.e., chronic)exposure to carbaryl.

Genotoxicity. Carbaryl tested positive in one of five gene mutation studies, four of sixchromosomal aberration studies and two of four DNA damage studies reviewed for thisassessment. It should thus be viewed as potentially genotoxic. Virtually all of the positivestudies were performed in vitro, which made them less relevant than in vivo studies to the wholeorganism. One study in V79 Chinese hamster fibroblasts showed that, like carbaryl, the carbarylmetabolite %-naphthol was toxic and induced c-mitosis, an aberrant form of mitosis that mayreflect effects on mitotic spindle formation. Nitrosocarbaryl, which caused single strand breaksin cultured human fibroblasts, was more efficiently formed in the guinea pig stomach than in therat stomach, an effect attributed to the more acidic conditions of the guinea pig stomach.

Oncogenicity. Carbaryl administered through the diet to mice over a two-year period inducedhemangiosarcomas and hemangiomas in both sexes, hepatocellular carcinomas and adenomasin females, and kidney tubular adenomas and carcinomas in males. Similar treatment in rats ledto hyperplastic and neoplastic signs in the urinary bladder of both sexes. These includedhyperplasia, transitional cell papillomas, transitional cell carcinomas, squamous metaplasia,high mitotic index and atypia. Tumors did not appear within a 6-month time frame in p53knockout mice, suggesting that carbaryl does not act through a p53-dependent mechanism.However, in view of the positive genotoxicity tests (see previous section), genotoxicity could notbe excluded as a possible component in carbaryl-induced cancers in mice. For this reason, andfor reasons of appropriate curve-fitting, the quantal linear model was used to define carbaryl'stumor potency with respect to hemangiosarcomas / hemangiomas in male mice.The potencyvalue in "at risk" animals, defined as the slope of the dose-risk relation, was 1.45x10-3

(mg/kg/day)-1 at the 95% upper bound and 7.2x10-4 (mg/kg/day)-1 at the maximum likelihoodestimate using the quantal linear algorithm after omission of the top dose. These potency valueswere extrapolated to humans using a dose equivalence based on body weight raised to the 3/4power or, in this case, a factor of 0.153. Thus the human equivalent potency values were1.01x10-2 mg/kg/day-1 (the 95% upper bound estimate) and 5.03x10-3 mg/kg/day-1 (themaximum likelihood estimate).

Reproductive toxicity. Several studies, both epidemiologic and animal, suggested thatcarbaryl is toxic to the reproductive systems of both males and females. An epidemiologic studyof agricultural workers indicated that the relative risk for miscarriage approximately doubledwhen carbaryl usage by males was combined with one of two other exposure categories,

5

including “crop herbicide application” and “application of crop insecticides and fungicides”. Anearlier epidemiologic study failed to establish “a definitive link between carbaryl exposure andhuman seminal defects”, though the data were suggestive of an increase in oligospermia(sperm count <20x106/ml) and teratospermia (>60% abnormal sperm forms) among workersand ex-workers in a carbaryl production facility. A more recent study showed sperm toxicity inoccupationally exposed factory workers. In addition, a positive correspondence between urinary1-naphthol levels and various indicators of sperm toxicity was demonstrated among malesseeking diagnoses for infertility.

Laboratory animal studies were equivocal in this regard. The clearest positive results came fromgavage studies in rats demonstrating impacts on testicular enzymes, sperm counts, spermmotility, sperm morphology and testicular morphology at a daily gavage dose of 50 mg/kg/day (5days/week, 90 days). An older study in gerbils also demonstrated impairment in severalreproductive indices.

Developmental toxicity. Outside of possible developmental delays likely mediated bymaternal weight gain suppressions, there was minimal evidence from guideline studies forcarbaryl-mediated developmental toxicity in rats and rabbits (though omphalocele was presentat relatively high doses in an older rabbit gavage study from the open literature). However, a1960s-era oral study in dogs demonstrated severe maternal and fetal effects followinggestational exposure: (1) increased dystocia at all dose levels (3.125-50 mg/kg/day); (2) threemothers sustaining total fetal deaths (one each at 6.25, 25 and 50 mg/kg/day); (3) decreasedpup weight gains in the combined treatment groups; (4) decreased conception rate at the highdose; (5) no pups born alive at the high dose; (6) decreased percentage of pups weaned, aneffect possibly present at as low as 6.25 mg/kg/day; and (7) increased litters with pups bearingabnormalities at and above 6.25 mg/kg/day. The abnormalities included “abdominal-thoracicfissures with varying degrees of intestinal agenesis and displacement, varying degrees ofbrachygnathia, ecaudate pups [i.e., without a tail], failure of skeletal formation, failure of liverdevelopment, and superfluous phalanges”.

Toxicity of 1-naphthol. Human exposure to 1-naphthol likely occurs through the metabolism ofcarbaryl or naphthalene. Exposure is also plausible through (1) the use of this chemical inmicroscopy, (2) as a coupler in cosmetic hair dyes, or (3) in the manufacture of dyes andintermediates. Pharmacokinetics. Male mice receiving 1-naphthol by oral gavage showed a 24-hr elimination of 68% in the urine and 13% in the feces; the major metabolites were 1-naphthylglucuronide and 1-naphthyl sulfate. A very limited study using three human male volunteersdetermined that 1-naphthol contained in an ointment was rapidly absorbed. Acute toxicity. Therat LD50 fell between 1870 and 2590 mg/kg. Signs and symptoms after acute exposure in ratsincluded tremors, abnormal respiration, subdued behavior, piloerection and labored breathing.Histopathologic changes were noted in the kidney and gut. Subchronic toxicity. Subchronicoral exposure resulted in gut erosion at a high dose of 200 mg/kg/day and a LOEL of 50mg/kg/day based on weight gain decrements and possible effects on female white blood cellcounts. Hematologic analysis revealed an apparent dose-related rise in white blood cell countsamong females, though the report claims that these increases were within the historical controlrange for the laboratory. Body weight gains were suppressed at all doses. Irritation. 1-Naphtholwas irritating to skin and eyes of rabbits. Teratogenicity / embryotoxicity. There was noevidence of any teratogenic or other adverse effect in the developing embryo / fetus afterdermal exposure up to 10 mg/kg/day every 3 days throughout gestation in the rat. Mutagenicity/ genotoxicity. Nine Salmonella / Ames studies using various strains were negative. One study

6

was positive in strain TA1538, with a maximal effect at 500 mg/plate in the presence of S9microsomes (negative in three other strains). Another study was positive in five strains in theabsense of S9 microsomes. A Rec assay in B. subtilis, was positive in the absence of S9 andnegative in the presence of S9. A plethora of other genotoxicity study types were negative.However, 1-naphthol, like carbaryl, induced an aberrant form of mitosis called c-mitosis thatmay reflect effects on mitotic spindle formation in V79 cells.

Toxicity of methylamine. Methylamine is produced upon hydrolytic breakdown of carbaryl,which occurs under alkaline conditions. This compound is known for its irritant effects in eyes,nose and throat upon brief exposures to 20 - 100 ppm. Severe methylamine exposure may leadto pulmonary edema. The oral LD50 in rats was 100 - 200 mg/kg. The L5178Y mutagenicityassay was positive. Gavage exposure of mice to 122 mg/kg methylamine for 5 days produced astatistically significant 27% drop in white blood cell counts.

Dietary exposure, risk calculations and risk appraisalThe potential for non-oncogenic health effects resulting from exposure to carbaryl wasexpressed as the Margin of Exposure (MOE). The MOE is defined as the ratio of the criticalLED10 value divided by the estimated exposure. A MOE of >100 was considered to be protectiveof human health when the relevant adverse effects were observed in animal studies, as is thecase in the present assessment.

Dietary pesticide exposure is the product of the amount of food that is consumed and theconcentration of the pesticide residue in that food. DPR dietary assessments consider onlythose commodities that carry a tolerance for the pesticide in question. For carbaryl, this includedseveral dozen commodities, in addition to drinking water. Carbaryl residues in food wereestablished mainly from the USDA’s Pesticide Data Program, with a small minority of residuevalues coming from FDA databases and field trials. The levels of commodity consumption camefrom the USDA’s 1994-1998 Continuing Survey of Food Intake by Individuals (CSFII). A dietaryexposure program developed by Exponent / Novigen Science, the Dietary Exposure andEvaluation Module (DEEM-FCID®), was used to calculate exposures for the US population as awhole and 18 separate geographic, ethnic and age-based subpopulations.

For estimating acute exposure, either the highest residue values below the tolerance or thedistribution of residues were considered. Exposure to carbaryl's most prominent degradate, 1-naphthol, was not included in the analysis. While the carbaryl tolerances for most commoditiesincluded 1-naphthol, and while the PDP program included residue data for this compound, itexhibited a substantially higher acute LD50 and subchronic LOEL than carbaryl. In addition, as adecarbamylated degradate, 1-naphthol was unlikely to be an effective cholinesterase inhibitor,which was the basis for the acute and chronic critical carbaryl NOELs.

Acute exposure to carbaryl was calculated on a per-user day basis, which included only thedays of survey in which each separate commodity was consumed. A tiered approach was usedto estimate acute dietary exposure. Residue values were set at tolerance (Tier 1), the highestmeasured value or limit of detection for each commodity (Tier 2), or were the result of acombination of the distributions of consumption and measured residue values (Tier 3 / MonteCarlo). Only data from Tiers 2 and 3 are presented in this assessment, as Tier 1 was viewed asa means to trigger the higher tiers.

For Tier 2, the highest exposures were predicted for infants and young children (1-2 yr and 3-5

7

yr age groups in particular). Acute Critical Exposure Commodity (CEC) analysis under Tier 2identified blueberries, peaches, apricots, apples, asparagus, olives, grapes and strawberries asmaking substantial (i.e., >5%) contributions to the acute dietary exposure of the highestexposure groups (infants, children 1-2 yr and children 3-5 yr) under Tier 2. The highcontributing commodities in the US population as a whole included apples, asparagus andblueberries.

Tier 3 refinement of the acute dietary exposure assessment using distributionally-determinedresidue values was made necessary by the sub-100 MOEs obtained under Tier 2 (see followingparagraphs). Lower exposure predictions and consequently higher MOEs were the result.Critical Exposure Commodity (CEC) analysis under Tier 3 identified cherries, rice, blueberries,peaches, pineapples, and plums (infants and children 1-2 yr) as major contributors. Cherriesand plums were the major contributors for the US population as a whole.

Acute MOEs calculated under Tiers 2 and 3 were as follows:

‚ Acute toxicity (NOEL = 1 mg/kg): Margins of exposure (MOEs) based on the highestresidue determination for each commodity (Tier 2) were below the health protective standard of100 for several subpopulations at the 95th user day percentile. At the 99th user day percentile,most populations showed MOEs less than 100, reaching as low as 24 for all infants and non-nursing infants <1 yr. A refined Tier 3 / Monte Carlo analysis was triggered because of theselow values.

There were no subpopulations exhibiting MOEs below 100 at the 95 or 99th user daypercentiles using Monte Carlo analysis (Tier 3). However, at the 99.9th percentile, threesubpopulations exhibited MOEs below 100: all infants (MOE=91), non-nursing infants <1 yr(MOE=76) and children 1-2 (MOE=92).

‚ Acute toxicity (LED10 = 0.25 mg/kg): Margins of exposure (MOEs) based on thehighest residue determination for each commodity (Tier 2) were below the health protectivestandard of 100 for all subpopulations at the 95th and 99th user day percentiles. The lowestMOEs at any percentile were found among infants, reaching 6 at the 99th percentile and 16 atthe 95th percentile for non-nursing infants <1 yr. For all infants these values were 6 and 19,respectively, while for nursing infants <1 yr they were 9 and 17. Because these values were solow, Tier 3 / Monte Carlo analysis was triggered.

Monte Carlo-derived MOEs at the 99.9th percentile fell below the health-protective standard of100 for almost all subpopulations. As with the point estimate data, the lowest MOEs occurredamong infants and young children 1-2 years, reaching 19 for non-nursing infants <1 yr at the99.9th percentile. Even at the 99th percentile there were many subpopulations registering MOEsbelow 100, including one (non-hispanic non-white non-black) that included adults. Allsubpopulations showed MOEs greater than 100 at the 95th percentile in the Monte Carloanalysis.

A tiered approach was not taken in the calculation of chronic exposure and MOEs, whichinstead were determined using per-capita mean consumption estimates. Children 1-2 yrexhibited the lowest MOE (highest chronic exposures) at 763, followed by non-nursing infantswith an MOE of 827. These were not considered to constituted a chronic dietary health concern.

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Oncogenic risk (or “lifetime risk”) was expressed as the product of the projected exposuremultiplied by the 95% upper bound on potency. The resultant unitless value represents the totalextra cases expected as a result of "lifetime" exposure to carbaryl. In the context of the DEEM-FCID®-based dietary assessment, the amortized lifetime exposure was the same as the chronicexposure output for the various adult subpopulations examined. Oncogenic risk ranged between2.54x10-6 and 3.83x10-6 for these subpopulations. For the US population as a whole, theoncogenic risk was 2.90x10-6. As these values were higher than the negligible risk standard of10-6, carbaryl was considered to constitute an oncogenic risk by the dietary route under currentuse conditions.

Reference doses (RfDs)Oral doses of a pesticide below a calculated RfD were unlikely to pose a risk to human health.RfDs were calculated for acute and chronic dietary exposure to carbaryl by dividing the criticaloral NOEL or LED10 by an uncertainty factor of 100 to account for variations in sensitivity inanimal and human populations.

Using the critical oral NOEL of 1 mg/kg, the resultant RfDacute was 0.01 mg/kg. Acute dietaryexposures calculated using the point estimate approach at the 95th percentile exceeded theRfDacute for all infants, nursing infants <1 yr, non-nursing infants <1 yr, children 1-2 yr andchildren 3-5 yr. Using the Monte Carlo approach at the 99.9th percentile, the RfDacute wasexceeded for all infants, non-nursing infants <1 yr and children 1-2 yr. These data suggest thatmitigation of carbaryl in food sources may be warranted.

Using the critical LED10 of 0.025 mg/kg, the resultant RfDacute was 0.0025 mg/kg. Acute dietaryexposures calculated using both the point estimate approach at the 95th percentile and theMonte Carlo approach at the 99.9th percentile exceeded the RfDacute for all of the subpopulationsthat yielded sufficient user day data. These data also suggest that mitigation of carbaryl in foodsources may be warranted.

Using the chronic LED10 of 0.5 mg/kg/day, the resultant RfDchronic was 0.005 mg/kg/day. Thehighest chronic dietary exposure estimate, which was recorded for children 1-2 yr, was only13% of the RFDchronic. By this measure, chronic exposure to carbaryl does not pose a non-oncogenic risk to any sub-population and does not currently warrant mitigation.

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Tolerance assessmentA separate acute tolerance assessment was conducted for each “high-contributor” commodity,defined for the tolerance assessment as those commodities providing greater than 5% of thetotal carbaryl consumption in the Tier 2 point estimate calculations at the 95th percentile asindicated by the Critical Exposure Contribution analysis for infants and children 1-2 yr. Thesecommodities included blueberries, peaches, asparagus, apricots, blackberries and apples.MOEs of less than 100 were indicated for every commodity examined where there weresufficient user days available, regardless of which critical acute toxicity value was used in theDEEM calculation. Consequently, tolerance values may require reevaluation in many cases.

A chronic exposure assessment using residue levels set to the established carbaryl toleranceswas not attempted, as it was highly improbable that single or multiple commodities containingpesticide levels at tolerance would be consumed habitually.

Comparison with USEPA's 2007 Reregistration Eligibility Document for carbarylAcute assessment: USEPA's acute "point of departure" (PoD) was 1.1 mg/kg, a benchmarkdose-derived LED10 value from brain cholinesterase inhibition data in postnatal day 11 rats. TheUSEPA PoD was essentially equivalent to DPR's critical acute NOEL of 1 mg/kg, but ~4-foldgreater than DPR's critical acute LED10 of 0.25 mg/kg. Combined with DPR's more selective useof surrogate residue data files in the Tier 3 / Monte Carlo exposure analysis, these criticaltoxicity values largely account for the differences between the two agencies in their estimationof risk. (DPR also used, wherever possible, only residue data collected in California.) USEPAconcluded that dietary exposure to carbaryl was lower than their target value of 100% of the"acute population adjusted dose" (aPAD) at the 99.9th user day percentile for all subpopulationsanalyzed. For example, the aPAD was 29% for the US population (equivalent to a MOE of 345),40% for all infants (equivalent to a MOE of 250) and 60% for children 1-2 yr (equivalent to aMOE of 167). Equivalent Tier 3 MOEs calculated by DPR for those subpopulations at the 99.9th

percentile were 164, 92 and 92 (NOEL = 1 mg/kg) and 41, 23 and 23 (LED10 = 0.25 mg/kg).DPR thus anticipates a higher level of risk from dietary exposure to carbaryl, regardless of thecritical acute toxicity term used to calculate MOEs.

Chronic assessment: USEPA did not estimate a chronic PoD for carbaryl, as it did not considerthat carbaryl, with its rapid dissociation from the cholinesterase enzyme, posed a chronic risk.DPR's chronic oral LED10 was 0.5 mg/kg/day (ED10 = 1.7 mg/kg/day). The lowest chronic MOEcalculated by DPR, 763 for children 1-2 yr, was considered to represent a negligible risk due tochronic dietary exposure.

Oncogenicity: USEPA regards carbaryl as a "likely human carcinogen". USEPA and DPRagreed that the formation of hemangiosarcomas in male mice, observed in the 2-year study wasthe most sensitive oncogenic endpoint (though DPR included hemangiomas). The 95% upperbound human equivalent potency slope values calculated by the two agencies were not similar,however, differing by a factor of 11.5-fold (USEPA: 8.75x10-4 mg/kg/day-1; DPR: 1.01x10-2

mg/kg/day-1). The major source of this discrepancy was almost certainly DPR's choice toeliminate the high dose in conducting the potency analysis. USEPA's consequent risk value,2.8x10-8 for the US population did not exceed the negligible risk standard of 10-6. DPR's range ofrisk values, 2.54x10-6 - 3.83x10-6 for the adult subpopulations analyzed and 2.9x10-6 for the USpopulation in general, clearly did exceed that standard.

Reproductive and developmental toxicity: USEPA did not express a high level of concern about

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the potential for reproductive or developmental toxicity, as the NOELs in the contract studieswere higher than the critical acute PoD of 1.1 mg/kg. Application of a Food Quality ProtectionAct safety factor of 1 reflected this view. DPR viewed reproductive toxicity mainly through thelens of epidemiologic studies, which indicated potential reproductive problems in males. DPRalso considered the developmental toxicity evident in an open literature study in beagle dogs toreflect a potential developmental risk.

California Proposition 65 (The Safe Drinking Water and Toxic Enforcement Act of 1986)Carbaryl has been listed as a developmental toxin in males under Proposition 65 since August7, 2009. In addition, the Office of Environmental Health Hazard Assessment announced inNovember 2009 its intent to list carbaryl as a carcinogen under Proposition 65.

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II. INTRODUCTION

A. CHEMICAL IDENTIFICATION

Carbaryl (1-naphthyl N-methylcarbamate; MW, 201.22) is a broad spectrum insecticide used tocontrol over 100 insect species, including moths, beetles, cockroaches, mosquitos and ants. Inaddition, the chemical is registered in California as a molluscicide and acaracide, thoughregistrations as a fungicide, herbicide, miticide, disinfectant and repellent are currently inactivein the state. Carbaryl is effective after ingestion by the targeted pest or after absorption followingbodily contact (http://extoxnet.orst.edu/pips/carbaryl.htm). Plant groups upon which carbaryl isused include citrus, fruit, vegetables, forage, forests, field crops, nuts, ornamentals, rangeland,turf and shade trees. In addition, there are significant residential, pet, lawn and garden uses.Carbaryl formulations include aqueous dispersions, baits, dusts, emulsifiable concentrates,flowables, granules, soluble concentrates, suspension concentrates, wettable powders andwater dispersible granules (Crop Protection Handbook, 2009).

As a member of the carbamate class of pesticides, the action of carbaryl is based largely on itsability to inhibit acetylcholinesterase (AChE) in the nervous systems and peripheral cholinergicsynapses of the target species (note: insects do not have peripheral cholinergic synapses).Carbaryl’s toxicity in mammalian systems is also based on this property. Carbaryl also inhibitsother cholinesterases (ChEs), including the plasma-localized butyryl ChE and the red blood cell-localized AChE. The contributions of these or other as yet unknown mechanisms to the overalltoxicologic picture are currently obscure.

In contrast to the organophosphates, carbamates do not form irreversible inhibitory bonds withChE molecules. Because of the relatively fast decarbamylation reaction, standard methods ofsample preparation may underestimate the extent of peak inhibition. This is because suchassays utilize extended incubation times at 37°C and large dilutions in buffer, both of whichfavor decarbamylation and consequent reactivation of the enzyme. More recent efforts havebeen made to develop ChE assay techniques that take into account the carbamate dissociationproblem (Padilla and Hooper, 1992; Nostrandt et al., 1993), though such techniques do notappear to have been utilized in most analyses of carbaryl-exposed tissues examined for thisdocument. This methodological conundrum is viewed as a limitation to the interpretation of theChE data in the present assessment. Even so, a recent assessment of carbamate-ChEinteractions supports the validity of the standard Ellman assay in the carbamate case,particularly at lower doses relevant to risk assessment, while continuing to recognize itsweaknesses (USEPA, 2005a).

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B. REGULATORY HISTORY

Carbaryl, originally manufactured by Union Carbide and now by Bayer Crop Science, was firstregistered for use on cotton in the United States in 1959 (USEPA [2004]). More than 100 foodtolerances are in effect for this chemical. USEPA has designated carbaryl to be a General UsePesticide. After conducting a Special Review of carbaryl, USEPA concluded in 1980 thattoxicologic concerns, particularly those relating to teratogenicity, did not warrant cancellation. ARegistration Standard promulgated in 1984 and revised in 1988 specified the requirements forcontinued registration (USEPA, 2004).

USEPA's Interim Reregistration Eligibility Decision (IRED), issued in October 2004, citedpossible health risks associated with residential and occupational exposures. This triggeredmitigation directives relating to personal protective gear, engineering controls, cancellation ofresidential aerosol products, packaging and application requirements for residential use andrestriction of residential lawn applications to spot treatment (USEPA, 2004, 2007a). The IREDalso cited possible impacts on non-target organisms and endangered species that may requiremitigation.

Requests for cancellation of all carbaryl uses were submitted by the Natural Resources DefenceCouncil and the Washington Toxics Coalition after publication of the IRED . While responses byUSEPA to these requests are still pending, the final Reregistration Eligibility Decision (RED),issued by USEPA in September 2007, stated "that there is a reasonable certainty that no harmwill result from aggregate non-occupational exposure to the pesticide chemical residue" forcurrently registered uses (USEPA, 2007a). A series of data call-ins issued in March 2005resulted in the voluntary cancellation of many products, as those registrants chose not to reviselabels or conduct support studies (USEPA, 2007a). The cumulative risks from exposure to theentire N-methyl carbamate class of pesticides through food, drinking water, residential use andother non-occupational exposures were judged by USEPA "meet the safety standard set forth insection 408(b)(2) of the FFDCA" (USEPA, 2007a and 2007c).

Finally, carbaryl has been listed as a developmental toxin in males under Proposition 65 sinceAugust 7, 2009. In addition, the Office of Environmental Health Hazard Assessment announcedin November 2009 its intent to list carbaryl as a carcinogen under Proposition 65 (OEHHA,2009).

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C. TECHNICAL AND PRODUCT FORMULATIONS

Carbaryl is registered in California as an insecticide, acaracide and molluscicide. Additionalregistrations as a fungicide, herbicide, miticide, disinfectant and repellent are currently inactivein the state. As of the last reported update of the DPR product database on Decmeber 2007,there were 53 carbaryl-containing products actively registered in California. The carbarylconcentrations in these products range between 0.126% and 97.5%. Several of theseformulations contain metaldehyde in addition to carbaryl. Registered products includeshampoos, dusts, powders, granulars / flakes, baits, liquids, flowable concentrates, aqueousconcentrates, emulsifiable concentrates, wettable powders, soluble powders, pellets / tablets /cakes / briquets, ready-to-use liquids, impregnated materials and suspensions.

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D. USAGE

According to DPR’s Pesticide Use Report, agricultural use of carbaryl declined steadily, both interms of pounds applied and acres treated, between 1994 and 2007 (Table II-1). In 2006 about142,000 pounds of carbaryl were applied commercially, compared to 821,000 pounds in 1994.Commodities receiving the highest amounts of carbaryl in pounds applied in 2007 were oranges(27,678 lb), processing tomatoes (25,255 lb), pistachios (9453 lb), pears (9236 lb), apples (8304lb), cantaloupe (6555 lb) and other melons (4740 lb).

Carbaryl has significant non-agricultural uses, particularly on lawns, gardens and pets. Unlikethe case with agricultural applications, non-agricultural applications are not strictly quantified inCalifornia. However, DPR’s Report of Pesticides Sold in California provides the total amount ofcarbaryl sold in the state in any given year. Comparing those values with the amounts applied inagricultural scenarios over several years gives a rough estimate of the amount of carbaryl usedin non-agricultural uses. By this calculation, an average of 63% (±15%) of the total carbaryl soldwas applied under agricultural conditions over the 1994-2007 period, with about 37% usedunder non-agricultural conditions. By way of comparison, the USEPA estimated that about halfof the carbaryl sold in the United States in 1998 was used in agricultural settings and half innon-agricultural settings (though the definition of these terms was not clear) (USEPA, 2004).

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Table II-1. Commercial carbaryl usage (pounds applied and acres treated) and total carbarylsold (pounds applied) in California, 1994-2007

Year Pounds sold aPounds applied a

(agricultural fraction) b Acres treated b

1994 1,264,283 820,787 (65%) 291,147

1995 1,242,400 835,811 (67%) 305,452

1996 834,427 810,162 (97%) 312,058

1997 1,142,675 754,659 (66%) 292,721

1998 506,764 427,546 (84%) 197,664

1999 639,600 388,144 (61%) 216,991

2000 563,605 364,060 (65%) 196,464

2001 412,635 286,199 (68%) 147,612

2002 421,528 256,098 (61%) 106,616

2003 329,782 205,102 (62%) 97,811

2004 388,235 240,135 (62%) 103,261

2005 412,955 190,633 (46%) 99,086

2006 411,711 156,938 (38%) 87,749

2007 323,069 142,010 (44%) 97,016a Data on pounds sold are from DPR’s Report of Pesticides Sold in California. Data on pounds applied andacres treated under commercial conditions are from DPR’s Pesticide Use Report. Both of these reportsare available at www.cdpr.ca.gov/dprdatabase.htmb Percentages represent the pounds applied divided by the pounds sold for a given year. They are anestimate of the fraction that is applied commercially.

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E. ILLNESS REPORTS

The following section summarizing the illness and injury reports in California to DPR isexcerpted from DPR's draft Human Exposure Assessment for Carbaryl (DPR, 2010 (inpreparation). References cited in this section are listed in that document.

Reports of illness and injury with definite, probable, or possible exposure topesticide products are recorded in a database maintained by the Pesticide IllnessSurveillance Program (PISP) at DPR. The PISP database contains informationabout the nature of the pesticide exposure and the subsequent illness or injury.“Definite” means that both physical and medical evidence document exposureand consequent health effects. “Probable” means that limited or circumstantialevidence supports a relationship to pesticide exposure “Possible” means thatevidence neither supports nor contradicts a relationship. (DPR, 2004). Reportswere summarized for illnesses associated with exposure to carbaryl alone or incombination with other pesticides for the 16-year time period, 1992-2007,inclusive (DPR, 2009). Illnesses were also classified based on types ofsymptoms described: systemic (symptoms such as headache, confusion, rapidpulse, dizziness, nausea); skin (symptoms such as irritation, rashes); eye(symptoms such as irritation, burning); respiratory (symptoms such as irritation,wheezing, shortness of breath). In addition to the PISP reports summarizedbelow, a detailed listing of illnesses reported in California from 1976 through1978 is also available (Peoples et al., 1981).

Carbaryl alone. From 1992-2007 there were 38 illness reports classified asdefinitely, probably, or possibly associated with the exposure to carbaryl, anaverage of about 2 illnesses per year. Among the symptoms reported weresystemic illnesses, (including respiratory illnesses), skin injuries, and eye injuries. Individuals involved in the handling process (applicators, mixer/loaders, flaggers)reported 11 illnesses and injuries. Sixteen of the 38 illnesses/injuries resultedfrom agricultural carbaryl applications. There were 14 days of disability and nohospitalizations resulting from agricultural carbaryl use. For non-agricultural usescenarios there were 30 days of disability (of which 18 days are suicide-associated) and 26 days of hospitalization (23 days are suicide-associated).

Carbaryl in combination. From 1992-2007, there were 60 illnesses classifiedas definitely, probably, or possibly associated with exposure to carbaryl used incombination with other pesticides. For the 16-year period, this averages to 4illnesses per year. The larger number of illnesses when carbaryl is incombination with other pesticides may be a reflection of the toxicity of the otherpesticides in the mixture, or it may be that carbaryl is used more often with otherpesticides than alone. Forty-eight of the 60 cases resulted from agriculturalactivities. Among the 48 cases, 16 illnesses and injuries occurred during thehandling process (applicator, mixer/loader, flagger). There were 52 days ofdisability and no days of hospitalization resulting from agricultural uses. For non-agricultural uses there were 6 days of disability and no hospitalization reported.

Illnesses Outside California. There are few illness reports involving carbaryloutside California. Case histories of illnesses associated with carbaryl have been

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reported from Illinois (Wiener and Young, 1995), Pennsylvania (Robinson, 1990),and New York (Dickoff et al., 1987). Most of these illnesses resulted fromintentional ingestion (Dickoff et al., 1987; Robinson, 1990). One case wasattributed to drift from weekly spraying by a next-door neighbor (Wiener andYoung, 1995).

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F. PHYSICO-CHEMICAL AND ENVIRONMENTAL PROPERTIES

Table II-2. Physico-chemical and environmental properties of carbaryl(Note: These values are taken from DPR's Environmental Monitoring Branch reports.References can be found therein (Appendix IX).

Chemical names 1-naphthyl N-methylcarbamate; 1-naphthenolmethylcarbamate; methyl carbamic acid 1-naphthylester

CAS registry number 63-25-2

Molecular weight 201.2

Molecular formula C12H11NO2

Physical state White crystalline solid (Union Carbide in support ofregistration 169-058)

Melting point 142°C

Density 1.23 @ 20°C

Solubility in water 113 ppm @ 22°C, 40 ppm @ 30°C a

Solubility in organic solvents methanol: 7960 ppm; hexane: 214 ppm; methylenechloride: 214,600 ppm

Vapor pressure 1.17 x 10-6 mm Hg 25°C

Log octanol-water partition coefficient (log Kow) 1.85 - 2.36

Henry’s Law constant 2.74x10-9 atm m3 g/mol at 25/C

Hydrolysis half-lives >1500 days @ pH 5; 12.1 days @ pH 7; 3.2 hr @ pH 9

Aqueous photolysis half-life 21 days (artificial light; pH 5)

Soil photolysis half-life 41 days (artificial light)

Aerobic soil half-life 4 - 17 days (sandy loam); 21-27 days (clay loam)

Anaerobic degradation half-life 78 days

Field dissipation half-life 0.76 - 10.9 days

Adsorption coefficient (Koc) 261a A value of 120 ppm @ 30°C was reported both in The Pesticide Manual: A World Compendium (SeventhEdition, ed. by C.R. Worthing. 1983. The British Crop Protection Council. p. 88) and in The Merck Index(Thirteenth Edition, ed. by M.J. O'Neil. 2001. Merck & Co., Inc. p. 1796), implying that there is somequestion as to the precision of the reported values.

19

G. ENVIRONMENTAL FATE

The following summary was extracted from DPR Environmental Monitoring reports by Xu and byGunasekara. These reports appear in full in Appendix IX.

Air. Carbaryl has a low vapor pressure (1.17 x 10-6 mm Hg 25°C) and low Henry’s Lawconstant (2.74x10-9 atm m3 g/mol at 25/C), both of which lower the tendency towardvolatilization. Even so, several studies have detected carbaryl in the air, even at remote sites,though the air concentrations are probably higher near the point of application. The presence ofthis molecule in air may be enhanced by association with particulates or spray droplets.

Water. Hydrolysis occurs rapidly at pH 7 and above; the degradation half-life is 10-17 days and3 hours at pH 7 and pH 9, respectively (25°C), while in “acidic” water it is 1500 days (27°C). 1-naphthol, methylamine and CO2 were identified as hydrolytic breakdown products. Thepresence of microorganisms is expected to enhance hydrolytic degradation. Photolysis isanother degradation pathway. The photolysis half-life for carbaryl in surface water was 64 hoursin spring, 52 hours in summer, 102 hours in fall and 200 hours in winter, demonstrating thecontribution of sunlight to the process. The major photolysis product is 1-naphthol, whichphotooxidizes to 2-hydroxy-1,4-naphtho-quinone under basic conditions. Though relativelyinsoluble in water, carbaryl has been found in both surface water and groundwater.

Soil. Carbaryl is subject to hydrolysis, photolysis and microorganism-mediated degradation insoil. Breakdown is enhanced in aerobic, as opposed to anaerobic, soils. Moderate binding tosoils is indicated by carbaryl’s soil adsorbtion coefficient (Koc = 100 - 600, with the precise valuedependent on soil type), octanol / water partitioning (log Kow = 1.85 - 2.36) and low watersolubility (113 ppm at 22°C - though see footnote #1, Table II-2). Soil binding is also favoredunder acidic conditions. Mud has been shown to enhance the removal of carbaryl from aqueoussystems, presumably by preferential binding. Carbaryl tends to be associated with the top 0 -0.15 meters of soil, showing a dissipation half-life of 0.76 - 10.9 days. Exchangeable cationssuch as potassium enhance the adsorption of carbaryl to soils. Soil adsorption capacity wasalso enhanced by the presence of organic matter.

Biota. While some bacterial species, including Achromobacter, Pseudomonas, Arthrobacter,and Xanthomonas, and at least one fungus (Penicillium implicatum) can metabolize carbaryl,both it and its major metabolite 1-naphthol are toxic to such beneficial soil-dwellingmicroorganisms as Chlorella vulgaris, Nostoc linckia and Synechococcus elongates. Microbialdegradation of carbaryl is enhanced under anaerobic conditions. Carbaryl is toxic to fish,aquatic invertebrates and non-target insects (honeybees), but relatively non-toxic to birds.Metabolism of carbaryl in plants is similar to that in animal systems.

20

III. TOXICOLOGY PROFILE

A. PHARMACOKINETICS

1. OverviewOrally administered carbaryl is excreted primarily through the urine in rats during the first 24hours (~60-90%, depending on dose), though substantial residues appear in feces (~6-20%)and in exhaled air as CO2 (detectable when carbaryl is labeled in the carbonyl or N-methylcarbon, but not when labeled in the naphthalene ring). The recovery kinetics in other laboratoryspecies examined (mouse, guinea pig, sheep) appeared generally similar, though there weresignificant technical problems with these latter studies, which were conducted in the 1960s,used very few animals and left large fractions of the administered dose unanalyzed. A possibleexception to the rat model was the dog, where approximately equal fractions were excreted inthe 24-hr urine and feces, though these data suffered from similar problems.

The major metabolic pathways, which are presumably predominantly hepatic, include (1) arene oxide-mediated hydroxylation and subsequent conjugation, (2) hydrolyticdecarbamylation to form 1-naphthol and subsequent conjugation, and (3) oxidation of the N-methyl moiety. Three urinary metabolites found in rat urine - 1-naphthyl glucuronide, 1-naphthylsulfate and 4-(methyl-carbamoyloxy)-1-naphthyl glucuronide - were not found in dog urine. Inaddition, minimal hydrolytic product was found in the urine of a single dosed monkey. Thetoxicologic significance of these apparent metabolic species differences was not clear. Humansdo appear to have the ability to decarbamylate carbaryl since carbaryl factory workers wereshown to excrete 1-naphthyl glucuronide and 1-naphthyl sulfate, leading to speculation thathumans are more similar to rats than dogs in their pharmacokinetic handling of carbaryl.However, a later study showed that intentionally dosed humans excreted only 25-30% of thecarbaryl in the urine at 24 hours, suggesting that the fate of very significant fractions of the dosewas unknown.

2. Pharmacokinetics in laboratory animalsStruble et al. (1994) studied the absorption, distribution, metabolism and excretion of 14C-naphthyl-carbaryl in HSD:SD rats, 4-8 wks old, 5/sex/dose. Groups A, B and C received ~1mg/kg carbaryl (labeled at the naphthalene-1 position), while group D received 50 mg/kg. GroupA was dosed intravenously; groups B-D were dosed by oral gavage. Group C was exposeddaily for 14 days with unlabeled carbaryl (1 mg/kg/day) prior to the radioactive dose. Apreliminary study showed that very little label was converted to CO2 or other volatilecompounds, obviating the need to monitor these parameters in the definitive study.

Clinical signs were noted only at the high dose (tremors and prostration @ 4-6 hr,lacrimation and salivation @ 6-12 hr, languidity and swollen faces @12-24 hr, normal after 24hr). An earlier group of group D animals dosed at 100 mg/kg were sacrificed @ 24 hr due tosevere toxicity.

No gender differences in the handling of carbaryl were evident in the analyses of urineand feces. Mass balance for all dose groups ranged between 96.1% and 104%. Comparisonwith the intravenous group (Group A) indicated 100% absorption in all groups (one exception:Group D males registered 94.3% absorption).

Table III-1 shows the time course for excretion of the administered label. Urine was theprimary route of excretion. For animals in Groups A-C (i.e., animals receiving 1 mg/kg), 48.1%-55.5% of the dose appeared in the urine during the first 6 hr, with 79.64%-90.86% by 24 hr and81.8%-92.0% by 168 hr. For Group D (animals receiving 50 mg/kg), urinary excretion wasslower, 12.5%-19.3% by 6 hr, 64.4%-68.4% by 24 hr, and 77.6%-81.2% by 168 hr.

1 This risk characterization document contains technical references to the acceptability, non-acceptability or supplemental quality of the studies used to gauge risk. These designations refer to eachstudy's status with regard to guidelines established through the Federal Insecticide, Fungicide andRodenticide Act (FIFRA). In this context, a "supplemental" designation indicates that the work was notdone using those guidelines. It should be emphasized that DPR does not necessarily base its judgement ofthe usefulness of a study for risk assessment purposes on the FIFRA designation. More to the point, asupplemental or unacceptable study can play an important or even critical role in the ultimate riskcharacterization.

21

Fecal excretion was significant, though it comprised a lesser proportion of theadministered dose than urinary excretion. By 168 hr, 6.98%-12.5% of the dose appeared in thefeces. The fraction of the dose appearing as cage rinse/wash/wipe did not exceed 10% by 168hr, though this fraction, which may originate as urinary or fecal “splash”, was higher in femalesthan in males.

Tissue levels accounted for less than 0.01% of the dose after 1 week. Carcass levelsaccounted for less than 1% of the dose after 1 week.

Metabolites were identified by comparison to reference standards using thin-layerchromatography (TLC), high pressure liquid chromatography (HPLC) and liquid chromatography/ mass spectrometry (LC/MS). Identified metabolites accounted for ~75% of the urinaryradioactivity and 1% of the fecal radioactivity. The major identified fecal metabolite was dihydro-dihydroxy carbaryl. Three major metabolic pathways were elucidated: (1) arene oxide formationwith subsequent metabolism to dihydro-dihydroxycarbaryl and conjugation with gluathione viathe mercapturic acid pathway; (2) carbamate hydrolysis to form 1-naphthol; and (3) oxidationof the N-methyl moiety. Metabolites were conjugated with sulfate or glucuronic acid. Theproposed metabolic scheme appears in Figure 1.

This study was considered acceptable by FIFRA standards. 1

22

Table III-1a Excretion time course for 14C-carbaryl administered intravenously (Group A) andby oral gavage (Groups B-D); male HSD:SD rats (Struble et al. [1994])

Feces(% of total dose)

Urine(% of total dose)

Cage rinse/wash/wipe(% of total dose)

Collection interval(hr)

GroupA

GroupB

GroupC

GroupD

GroupA

GroupB

GroupC

GroupD

GroupA

GroupB

GroupC

GroupD

0-6 0.78±1.729

nda nd 0.04±0.042

55.5±8.17

49.6±8.54

51.5±16.56

19.3±3.73

nda nd nd nd

6-12 6.21±2.905

4.88±1.453

4.39±0.744

1.26±2.809

23.7±11.09

29.7±8.21

31.8±16.45

22.9±1.85

nd nd nd nd

12-24 2.32±0.578

3.70±0.76

3.60±1.731

7.93±2.246

4.81±0.943

7.56±1.272

7.56±1.804

26.2±5.11

2.92±1.344b

3.50±2.091b

2.49±1.071b

5.81±2.555b

0-24 d 9.31 8.58 7.99 9.23 84.01 86.86 90.86 68.40

24-48 0.67±0.491

0.40±0.114

0.49±0.144

2.82±1.254

1.14±0.423

0.88±0.255

0.84±0.215

7.65±1.916

nd nd nd nd

48-72 0.07±0.032

0.05±0.011

0.06±0.047

0.27±0.118

0.22±0.164

0.13±0.056

0.11±0.030

0.62±0.236

nd nd nd nd

72-96 0.04±0.017

0.02±0.010

0.01±0.009

0.09±0.052

0.11±0.082

0.06±0.022

0.05±0.009

0.32±0.174

nd nd nd nd

96-120 0.05±0.040

0.01±0.013

<0.01 0.04±0.013

0.09±0.102

0.04±0.024

0.05±0.027

0.30±0.330

nd nd nd nd

120-144 0.02±0.015

<0.01 0.01±0.022

0.03±0.019

0.08±0.060

0.04±0.025

0.03±0.013

0.19±0.149

nd nd nd nd

144-168 0.02±0.015

<0.01 <0.01 0.02±0.007

0.06±0.038

0.06±0.076

0.02±0.013

0.15±0.097

0.72c 0.46c 0.48c 1.01c

Total 10.2±2.65

9.06±1.157

8.57±0.992

12.5±2.05

85.7±3.62

88.1±1.98

92.0±3.10

77.6±4.61

3.64±1.356

3.96±2.137

2.97±1.197

6.82±2.778

Note: Group A, 1 mg/mg 14C-carbaryl, iv; Group B, 1 mg/mg 14C-carbaryl, oral gavage; Group C, 1mg/mg 14C-carbaryl oral gavage after 14 days of 1 mg/mg/day unlabeled carbaryl, oral gavage; Group D,50 mg/mg 14C-carbaryl oral gavage.a Not determined. For the cage rinse/wash/wipe determinations, the value represents the percent retrievedat the latter time point only.b Cage rinse only.c Cage wash + cage wipe (combined for simplicity; no standard deviation).d For the time 0-24 hr interval, the percentages for the previous intervals were added together by the riskassessor. Consequently, no standard deviations were presented.

23

Table III-1b. Excretion time course for 14C-carbaryl administered intravenously (Group A) andby oral gavage (Groups B-D); female HSD:SD rats (Struble et al. [1994])

Feces(% of total dose)

Urine(% of total dose)

Cage rinse/wash/wipe(% of total dose)

Collection interval(hr)

GroupA

GroupB

GroupC

GroupD

GroupA

GroupB

GroupC

GroupD

GroupA

GroupB

GroupC

GroupD

0-6 nda nd 0.10±0.222

0.11±0.110

48.5±3.57

48.1±6.74

53.4±6.33

12.5±5.95

nda nd nd nd

6-12 5.15±2.007

3.87±2.704

2.93±2.780

0.10±0.233

26.7±8.12

23.6±4.68

21.6±4.32

21.4±6.49

nd nd nd nd

12-24 2.73±2.440

3.97±1.671

3.95±2.173

1.92±2.843

5.66±1.846

7.94±3.522

8.09±2.256

30.5±4.79

4.54±3.196b

9.04±4.288b

9.56±2.292b

6.46±2.763b

0-24 7.88 7.84 6.98 2.13 80.86 79.64 83.09 64.40

24-48 0.51±0.297

0.39±0.143

0.52±0.232

3.98±1.651

1.52±0.798

1.64±0.792

1.36±0.602

14.2±7.49

nd nd nd nd

48-72 0.13±0.088

0.06±0.024

0.06±0.024

0.60±0.285

0.38±0.229

0.23±0.083

0.19±0.061

1.67±1.189

nd nd nd nd

72-96 0.06±0.019

0.03±0.013

0.04±0.015

0.13±0.055

0.20±0.095

0.14±0.060

0.10±0.037

0.43±0.280

nd nd nd nd

96-120 0.06±0.037

0.06±0.095

0.03±0.021

0.05±0.031

0.15±0.104

0.08±0.047

0.07±0.012

0.19±0.151

nd nd nd nd

120-144 0.04±0.016

0.02±0.011

0.04±0.048

0.06±0.043

0.11±0.055

0.07±0.038

0.06±0.044

0.17±0.130

nd nd nd nd

144-168 0.03±0.013

<0.01 <0.01 0.03±0.015

0.09±0.035

0.06±0.041

0.04±0.013

0.12±0.082

0.78c 0.65c 0.44c 0.49c

Total 8.71±3.430

8.40±1.562

7.68±0.785

6.98±1.222

83.3±3.12

81.8±5.38

85.0±1.68

81.2±2.50

5.32±3.085

9.69±4.231

10.0±2.32

6.95±1.75

Note: Group A, 1 mg/mg 14C-carbaryl, iv; Group B, 1 mg/mg 14C-carbaryl, oral gavage; Group C, 1mg/mg 14C-carbaryl oral gavage after 14 days of 1 mg/mg/day unlabeled carbaryl, oral gavage; Group D,50 mg/mg 14C-carbaryl oral gavage.a Not determined. For the cage rinse/wash/wipe determinations, the value represents the percent retrievedat the latter time point only.b Cage rinse only.c Cage wash + cage wipe (combined for simplicity; no standard deviation).d For the time 0-24 hr interval, the percentages for the previous intervals were added together by the riskassessor. Consequently, no standard deviations are presented.

24

Figure 1. Proposed metabolic pathways for carbaryl (from Struble et al. [1994])

OH OCONHCH3 OCONHCH2OH

OCONHCH2OHOGlucOSO3H

HO

OCONH2OCONHCH3

O

OCONHCH3

O HO

OCONHCH3

HO

S-GSH

OCONHCH3

OH

HO

OCONHCH3

OH

OCONHCH3

OH

OCONHCH3

OH

OH

OCONHCH3

HO

SCH2CH(NHCOCH3)CO2H

OCONHCH3

OH

OH

1-Naphthol Carbaryl

Conjugation

Sulfate Glucuronic acid

Oxidation

N-(hydroxymethyl)hydroxycarbaryl

Arene oxideformation

α-Naphthyl sulfate α-Naphthyl β-O-glucuronide

Hydroxy-desmethylcarbaryl

Acid hydrolysis

Epoxide hydraseGSH transferase(Mercapturic acid pathway)

5-Hydroxycarbaryl 4-Hydroxycarbaryl

Conjugation

1,5-Dihydroxynaphthalene

Hydrolysis

(OH,OGluc)

Glucuronide conjugateof dihydrodihydroxycarbaryl

Conjugation

S-(N-Acetylcysistryldihydrodihydroxycarbaryl

1.Protease2.N-Acetyl transferase

"Conjugated carbaryl"

Carbaryl

Acid hydrolysis

= Probable intermediates

Hydrolysis Alkyl oxidation

25

Totis (1997) conducted a pharmacokinetics study to “investigate the mechanisms that causedthe appearance of an increased incidence of tumours during the final year of a chronic dietaryfeeding study in the rat at the high dose level of 7500 ppm. For this purpose, a series ofexperiments were performed using the 15 month old male [CD] rat.”

There were 5 experimental groups: Group A, single gavage administration at the samehigh dose level (~50 mg/kg 14C-carbaryl, labeled in the naphthylene ring) used in the Struble etal. (1994) study; Group B, 0 ppm (control) dietary administration group; Group C, 250 ppmdietary administration group; Group D, 7500 ppm dietary administration group; Group E, 1500ppm dietary administration group (this group was done later than the other groups). Groups B-Ewere dosed at the indicated dietary level for 83 days (except where indicated) followed by aweek of gavage administration with 2 mg/kg/day 14C-carbaryl. Group A comprised 5 animals.Groups B-E comprised 25 animals (5/group used for mass balance, 5/group for urinary / fecalmetabolism identification, 10/group used for metabolism identification in tissues, 5/group dosedwith dietary carbaryl for 90 days and used for histopathology and enzyme activitydeterminations). The achieved doses in groups C, D and E were 9.89, 250.71 and 58.96mg/kg/day, respectively, over 13 weeks.

Body weights were significantly less than controls at 7500 ppm on days 14, 29 and 83(day 83 mean weights, 0 ppm: 767.1 g; 7500 ppm: 613.9 ppm**; p<0.01), with an increase inliver, spleen and thyroid weights (absolute and relative to body weight). Liver histopathologyindicated centrilobular hypertrophy, pericholangitis and a tendency toward bile duct hyperplasiaat 7500 ppm. Liver glutathione concentration was also elevated at 7500 ppm (46.8 vs. 94.40**µmol/g liver @ 0 and 7500 ppm, respectively; **p#0.01). Thyroid follicular cell hypertrophy wasnoted in 0/5, 3/5, 5/5 and 5/5 rats at 0, 250, 1500 and 7500 ppm. Kidney transitional cellhyperplasia was noted in 0/5, 0/5, 1/5 and 2/5 rats at those doses.

In the dietary administration groups (Groups B-E), 64-90% of the administered dose wasexcreted in the urine within the first 24-48 hr (the 7500 ppm group had the lowest urinaryexcretion levels), with 8-18% in feces. For the single dose 50 mg/kg group, 63% had appearedin the urine and 5% in feces by 48 hr. There were 23 metabolites in urine and twenty in feces,including carbaryl. The major urinary metabolites were UMET/11 (glucuronide of dihydro-dihydroxy carbaryl), UMET/18 ("-naphthyl-$-D-glucuronide, sodium salt) and UMET/23 (sulfoconjugate of naphthol). The appearance of UMET/11 in the urine increased at 1500 and 7500ppm, while UMET/23 (sulfo-conjugate of the naphthol) decreased, particularly at 7500 ppm.Tissue levels were low, with the kidneys generally containing the most residual activity (thougheven kidney levels were less than 1% of the administered dose). It was concluded that 15-18month male rats are capable of significant metabolism of carbaryl, similar to the young ratsstudied by Struble et al. (1994).

As this study was not executed according to FIFRA guidelines, it was considered to besupplemental.

********************

Similar to the Totis (1997) study in rats, Valles (1999) initiated a study in CD1 mice to“investigate the contribution of metabolism to the mechanisms that resulted in the appearanceof an increased incidence of tumours during the final year of a chronic dietary feeding study [inmice] at the dose level of 1000 and 8000 ppm”. Males (10/dose) were fed diets containing 0, 10,100, 1000 or 8000 ppm carbaryl for 14 days, followed by a single gavage dose of 50 mg/kg 14C-carbaryl (labeled at the naphthalene-1 position) on day 15. Assuming a food consumption rateof ~6 g/day and body weights of about 0.03 kg, these doses corresponded to carbaryl doses ofapproximately 0, 2, 20, 200 and 1600 mg/kg/day. Urine and feces were collected at 24-hrintervals for a total of 168 hr following dosing, after which the animals were sacrificed.

26

Radioactivity in the carcass and blood was also determined. The metabolites in pooled urinewere quantified for 0-24, 24-48 and 48-96 hr.

Urine was the major excretory route. Within the first 24 hr, 45-59% of the dose appearedin the urine. By 48 hr and 168 hr, it had climbed to 53-68% and 55-70%, respectively. If cagewashes were added to urine (on the assumption that the radioactivity in this fraction originatedas urinary “splash”), the total urinary excretion by 168 hr was 83.55% (0 ppm), 72.71% (10ppm), 80.73% (100 ppm), 84.17% (1000 ppm) and 79.41% (8000 ppm). Fecal excretionaccounted for 12-19% of the dose by 168 hr.

Twenty-one metabolites were detected in the urine. The four major metabolites, found inall dose groups, were: (1) dihydro, dihydroxynaphthyl sulfate, (2) hydroxycarbaryl glucuronide, (3) "-naphthyl sulfate and (4) "-naphthyl $–D glucuronide. Three of these (#2-4) had beenidentified in 15-18 month old male rats by Totis (1997), suggesting that mice metabolizedcarbaryl in a manner that was qualitatively similar to the rat, but with some quantitativedifferences. There was a shift in the urinary metabolite pattern at 8000 ppm, with increases in(1) and (2) above, which are apparently formed by epoxide intermediates. Therefore, high dosesof carbaryl could alter the metabolism, distribution and excretion patterns for this compound.The authors considered it plausible that such a metabolic transition at high doses could accountfor the oncogenicity of this compound in mice (see Hamada [1993b], summarized below insection III.D.2.) and in rats (see Hamada [1993a], summarized below in section III.D.2.).

This study was deemed supplemental.********************

Krolski et al. (2003a) investigated the pharmacokinetic behavior of carbaryl after exposure bythe oral, dermal and intravenous (iv) routes. Thirty two male Sprague-Dawley rats / group weretreated as indicated: (1) oral gavage with either 1.08 mg/kg [naphthyl-1-14C]-carbaryl or 8.45mg/kg [naphthyl-4a,5,6,7,8,8a-14C]-carbaryl; (2) dermal, up to 10 hr exposure with either 17.25mg/kg [naphthyl-1-14C]-carbaryl or 102.95 mg/kg [naphthyl-4a,5,6,7,8,8a-14C]-carbaryl; (3) ivinjection with either 0.80 mg/kg [naphthyl-1-14C]-carbaryl or 9.20 mg/kg [naphthyl-4a,5,6,7,8,8a-14C]-carbaryl. For the oral and dermal routes, 4 animals / time point were euthanized at 15 and20 min and at 1, 2, 4, 6, 12 and 24 hr post dose. For the iv route, 4 animals / time point wereeuthanized at 5, 10, 20 and 30 min and at 1, 2, 4 and 8 hr post injection. Total radioactiveresidues (TRR) were determined in the whole blood, plasma, RBCs and brain of all animals.Liver and fat tissue from high dose animals were also assayed for TRR. Composite sampleswere analyzed for parent compound or specific metabolites. Urine and fecal samples were notcollected.

Peak levels of radioactivity were detected in the blood at 15 and 30 min for the low andhigh dose oral treatments, respectively; at 4 and 12 hr for the dermal applications; and werealready maximal by the first time point (5 min) for the iv injections. Oral dosing: by 24 hr,radioactivity levels had decreased to 0.81%-2.4% of peak levels in blood fractions (both doses),0.60%-2.4% in brain (both doses), 0.67% in liver (high dose only) and 0.32% in fat (high doseonly). Dermal dosing: by 24 hr, radioactivity levels had decreased to 15.9%-25.8% of peaklevels in blood fractions (both doses), 27.1%-30.6% in brain (both doses), 24.4% in liver (highdose only) and 15.6% in fat (high dose only). Iv dosing: by 24 hr, radioactivity levels haddecreased to 4.6%-10.5% in blood fractions (both doses), 1.1%-1.3% in brain (both doses),5.7% in liver (high dose only) and 0.72% in fat (high dose only).

Metabolic analysis revealed that carbaryl was rapidly degraded through hydrolysis of thecarbamate ester linage, as indicated by the recovery of more polar compounds, 1-naphthol and1-naphthol sulfate in the plasma. N-hydroxy-carbaryl was recovered as a minor metabolite in thebrain. By 24 hr post oral dose and 8 hr post injection dose the carbaryl level in the brain had

2Comparison with the dermal regimen in Krolski et al. (2003a) at 17.25 mg/kg showed the bloodpeak occurring at 4 hours in that study, with little evidence of a contribution at 1 hour. The exposureregimen in that study continued for 10 hours, unlike the current study where exposure was discontinuedafter 2 hours.

27

fallen to 0.4 and 0.1% of the peak levels, respectively. Similar metabolic patterns were seen inthe liver and fat.

As this study was not conducted according to FIFRA guidelines, it was considered to besupplemental.

Krolski et al. (2003b) extended the above study by exposing Sprague-Dawley ratssimultaneously by the oral and dermal routes. Twenty males received two gavage doses of0.085 mg/kg; there was a 1-hour interval between the doses. Concomitantly, a 2-hour dermalexposure of 0.871 mg/kg was also executed. The test material was [naphthyl-4a,5,6,7,8,8a-14C]-carbaryl. Four animals per time point were euthanized at 0.25, 0.5, 1, 3 and 5 hours after thesecond oral dose. Total radioactive residues (TRR) were determined in whole blood, plasma,RBCs and brain of all animals.

Peak levels of radioactivity occurred in the blood and brain 15 minutes after the secondoral dose (i.e., while the dermal exposure was still occurring), though no measurements weretaken during the first hour. A slight upward inflection of the TRR vs. time curve for whole bloodmay reflect a contribution from the dermal component, though this could not be verified 2.Analysis of the metabolites in the brain revealed that carbaryl was degraded through hydrolysisof the carbamate ester linkage as indicated by the recovery of more polar metabolites, 1-naphtoland 1-naphthol sulfate.

As this study was not conducted according to FIFRA guidelines, it was considered to besupplemental.

********************

Thomas (1994) initiated a study “to identify and phenotype a prospective cytochrome p-450inducing potential of carbaryl in the livers of male CD1 mice following dietary administration ofthe test article at a dose level of 8000 ppm (8000 mg/kg diet) for 14 consecutive days”. Thisstudy was part of a larger study which examined carbaryl’s potential for DNA damage (orchromosomal aberrations; see section III.G.). Frozen livers were thawed, homogenized andcytosolic and microsomal fractions obtained by centrifugation. Body weights in treated micewere 85% of controls (28.88 g vs. 34.08 g; p<0.001). Relative liver weights were increased to135% of controls (6.47% vs. 4.79%; p<0.01). Microsomal protein was increased to 132% ofcontrols (22.75 mg/g liver vs. 17.23 mg/g liver; p < 0.01). Cytochrome p-450 was elevated 1.3-fold over controls (15.13 nmol/min/g liver vs. 11.21 nmol/min/g liver; p<0.05), 7-ethoxyresorufino-de-ethylase (EROD) 1.9-fold over control (4.09 nmol/min/g liver vs. 2.15 nmol/min/g liver;p<0.05), 7-pentoxyresorufin o-de-ethylase (PROD) 3.1-fold over control (0.655 nmol/min/g livervs. 0.209 nmol/min/g liver; p<0.01), and total testosterone hydroxylation 1.52-fold over control(86.59 vs. 56.95 nmol/min/g liver; p<0.05). The slightly increased level of glutathione did notreach statistical significance. Carbaryl was considered to be a weak barbiturate-type inducer ofcytochrome p-450 in male mice.

This study was considered to be supplemental.********************

The following three paragraphs summarize three older metabolism studies from Knaak et al.

3 The 21% discrepancy for the carbaryl-methyl-14C, 4-day urinary value reported in the recoveryexperiment in the first paragraph was unexplained and only partially accounted for by the difference incollection time: 24 hr in the metabolite experiment vs. 4 days in the recovery experiment (recovery at 24hr in the latter experiment was ~69%). Based on animal weights of ~150 g, the doses for the twoexperiments (20 mg/kg in the recovery experiment, 300 mg/animal in the metabolite experiment) wereequivalent, so could not account for the discrepancy.

28

(1965, 1967, 1968) in several species. Knaak's rat data largely support Struble (1994), though itappears that the dog may excrete a higher proportion of the naphthyl residues in the fecalfraction and may not produce certain metabolites in the urine (Knaak, 1967). However, Knaak'sstudies used low animal numbers and did not analyze the metabolites in large fractions of thetotal dose, particularly in the feces.

Knaak et al. (1965) studied the metabolism of carbaryl in the rat and guinea pig afterintraperitoneal administration of carbaryl-naphthyl-14C, carbaryl-methyl-14C or carbaryl-carbonyl-14C. When 4 rats each (sex not stated) were dosed by gavage with 20 mg/kg of thesecompounds, an average of 94% was excreted over a 7-day period, with excretion essentiallycomplete in 3 days. The approximate percent of dose in urine / feces / CO2 after 4 days was, forcarbaryl-naphthyl-14C: 72% / 10% / 0%; for carbaryl-methyl-14C: 69% / 7% / 11%; for carbaryl-carbonyl-14C: 47% / 8% / 32%. As might be expected, carbaryl-naphthyl-14C was not detected as14C O2, while carbaryl-methyl-14C and carbaryl-carbonyl-14C produced CO2 at 11% and 32% ofthe dose, respectively. Two to 3% of the methyl-14C dose was recovered in the intestinal tract,carcasses and remaining organs (neither naphthyl-14C nor carbonyl-14C residues were detectedin tissues). Recovery data for guinea pigs were not presented.

Urinary metabolites of carbaryl-naphthyl-14C, carbaryl-methyl-14C and carbaryl-carbonyl-14C (rat only) were examined in the rat and guinea pig using DEAE-cellulose and thin layerchromatography. Pooled samples collected during the first 24 hours after intraperitonealinjection of 3 mg in 300 mg of polyethylene glycol 400 to each of 3 male rats and 3 guinea pigs(sex not stated) were examined. In the rats, the 24-hr samples yielded 73%, 47% and 48% ofthe naphthyl, methyl and carbonyl doses, respectively 3, while in the guinea pigs the naphthyland methyl ligands yielded 85% of the dose (separate values for each ligand were not reportedfor guinea pigs). The following urinary metabolites were identified: 1-naphthyl methylcarbamateN-glucuronide (guinea pig only), 1-naphthyl methylimidocarbonate O-glucuronide (the mostprominent identifiable metabolite of all three compounds in rat urine at 26.0-45.3% of therecovered 14C and the most prominent identifiable metabolite of carbaryl-methyl-14C in guineapig urine at 30.1% of the recovered 14C), 4-(methylcarbamoyloxy)-1-naphthyl glucuronide, 1-naphthyl glucuronide (the most prominent metabolite of carbaryl-naphthyl-14C in the guinea pigat 26.5% of the recovered dose), 4-(methylcarbamoyloxy)-1-naphthyl sulfate, 1-naphthyl sulfate,unidentified neutrals, and two unidentified metabolites (one of which was found only in theguinea pig).

Rat and guinea pig liver microsomes incubated with carbaryl-naphthyl-14C in thepresence of a hydrogen donor (NADPH2) and uridine diphosphoglucuronide (UDPGH) formed aspectrum of metabolites. These included unidentified water-soluble neutrals, 4-(methylcarbanoyloxy)-1-naphthyl glucuronide, 1-naphthyl glucuronide and two unidentifiedmetabolites (one of which was found only in the rat system). The only major urinary metabolitesnot formed by the liver preparations were 4-(methylcarbamoyloxy)-1-naphthyl sulfate and 1-naphthyl sulfate.

Fluorescence chromatograms were conducted on 24-hr pooled urine samples from men

4 Calculations by the risk assessor (A. Rubin) did not precisely verify these values. In the 24-hrpooled rat urine samples, carbamate-intact metabolites from the three ligands accounted for 47%-68% ofthe total radioactivity, while in the guinea pig such metabolites from the two ligands accounted for 47%-67% of the total radioactivity.

29

exposed to carbaryl dust in a packaging operation at a Union Carbide plant (though the numberof men was not stated). The only detectable metabolites were 1-naphthyl glucuronide (~25µg/ml) and 1-naphthyl sulfate (~5 µg/ml). These data demonstrated that humans can hydrolyzeand conjugate carbaryl. The apparent absence of other metabolites may be a function of thesensitivity or timing of the fluorescence assay.

In conclusion, as stated in the report (p. 542-3), “Carbaryl is metabolized in the rat andguinea pig to a series of eight or more water-soluble compounds. Forty-seven to 57% of themetabolites excreted possess the intact C-O-C(O)N-C structure, indicating that a nonhydrolyticpathway exists for carbaryl.... Thirty-nine to 44% of the administered carbaryl was hydrolyzedand the liberated 1-napththol conjugated with glucuronic and sulfuric acids.” 4 In addition, thestudy confirmed the ability of humans to hydrolyze (decarbamylate) and conjugate carbaryl.

While this study contains useful data, the intraperitoneal exposure route may not berepresentative of oral, dermal or inhalation exposure. Furthermore, (1) the sex of the animalswas not always identified in this study, (2) there were relatively few animals tested, and (3) the24-hr urine samples did not account for large portions of the initial dose. As a result, much ofthe metabolic picture in rats and guinea pigs (not to mention humans) was not characterized bythe study. This study was considered to be supplemental.

Knaak et al. (1968) studied the metabolism of carbaryl in the monkey (1 female rhesus), pig (2females) and sheep (1 female) after administration of either carbaryl-naphthyl-14C or carbaryl-methyl-14C. The monkey received a dose of 300 mg/kg. The pigs and the ewe received a doseof 25 mg/kg. In addition, two human males received a 2 mg/kg dose of unlabeled carbaryl.Doses were administered orally in gelatin capsules. Urinary metabolites were elucidated byDEAE-cellulose ion exchange chromatography.

The pigs excreted 83.4% and 1.6% of the naphthyl label in the urine and feces,respectively, within 5 days of oral administration in gelatin capsules. The parallel study with themethyl label resulted in 70% and 1% appearing in urine and feces. Results for the ewe were71.4% and 3.4% for the naphthyl label and 62.4% and 5.4% for the methyl label after 4 days.Humans excreted about 25-30% of the carbaryl in the urine within 24 hr, with very little excretionthereafter, as determined by fluorescence chromatography. Recovery data were not reported forthe monkey.

A spectrum of metabolic products resulting both from hydroxylation and hydrolysis ofcarbaryl were noted in the 24-hr urine samples of all species tested. In the pig, two majormetabolites possessing the intact carbamate structure (i.e., C-O-C(O)-N-C), including 1-naphthyl methylimidocarbonate O-glucuronide (compound D: 38-46% of total 14C recoveredfrom the column) and 4-(methylcarbamoyloxy)-1-naphthyl glucuronide (compound F:15-16%),were recovered. In addition, unidentified neutrals (referred to as compound A, probablyincluding parental carbaryl and naphthol: 10-23%) and one hydrolysis product, 1-naphthylglucuronide (compound G: 5.5%) were also detected. The ewe excreted five intact carbamates:compounds D (26-42%), F (13-24%), H (4-(methylcarbamoyloxy)-1-naphthyl sulfate: 4-13%),and two unidentified intacts not identified in rat, guinea pig, monkey or pig urine (compound J:6.9% and compound K: 3-9%). Also identified in ewe urine were neutral compound A (3-14%),and two hydrolysis products, compounds G (11.9%) and I (1-naphthyl sulfate: 25.2%). The

30

monkey excreted three intact carbamates, including compounds D (16-18%), F (31-38%) and H(14-26%), in addition to neutral compound A (16-17%). Virtually no hydrolyzed metabolites (i.e.,compounds G or I) were excreted in monkey urine.

The following urinary metabolites were detected in male humans: unidentified neutrals(compound A, not quantitated), an unidentified metabolite (compound C, not quantitated),compound D (not quantitated), compound F (4-6%), compound G (10-16%), compound H (0% -interpreted as trace), and compound I (6-11%). These results confirmed the ability of humans tohydrolyze the carbamate moiety (i.e., decarbamylate) observed by Knaak et al. (1965).However, in view of the small fraction of the total dose appearing in the human 24-hr urinesamples (~30%, as noted in the second paragraph above), it is difficult to draw conclusionsconcerning the overall metabolite profile in humans. The monkey showed little tendency tohydrolyze carbaryl; the pig had somewhat greater tendency, but less than sheep or humans. The metabolite profiles for rat and man appeared qualitatively similar, with the caveat that only afraction of the human excretion profile was analyzed.

Some data from this study may be useful, though very few animals were tested and the24-hr urine samples did not account for sufficient portions of the initial dose, particularly inhumans. As a result, much of the metabolic picture remained unclear for these species.

This study was considered to be supplemental.

Knaak and Sullivan (1967) studied the metabolism of carbaryl in three female beagles. Eachanimal was dosed successively (one week apart) with carbaryl-naphthyl-14C and carbaryl-methyl-14C. The dose for each ligand was 25 mg/kg. Urine and feces were collected over a 7-day period. Urinary metabolites were analyzed in first day urine samples by ion exchange, thinlayer chromatography and fluorometry.

Excretion was essentially complete by 4 days. For carbaryl-naphthyl-14C, about 38% ofthe dose was excreted in the urine and ~35% in the feces. Thus ~73% of the dose was excretedby those routes in that time. For carbaryl-methyl-14C, about 21% of the dose appeared in theurine and ~11% in the feces, resulting in about 32% of the dose excreted by those routes. Theunequal distribution of these two labels was interpreted as evidence that an N-methyl hydrolyticpathway exists in the dog. The presence of essentially equivalent amounts of carbaryl-naphthyl-14C in the feces as in the urine presents a quantitative difference from the rat, which excretesless than 10% of the carbaryl-naphthyl-14C in the feces compared to 77-92% in the urine after 1week (Struble et al. [1994]; Knaak [1965] shows approximately the same proportions).

Three important urinary metabolites normally found in rat urine were not found in thedog: 1-naphthyl glucuronide, 1-naphthyl sulfate and 4-(methyl-carbamoyloxy)-1-naphthylglucuronide. Most other rat metabolites (see the studies summarized above) were also found indog urine. As stated in the report (p. 1126): “...the major difference between the rat and dogappears to be the inability of the dog to liberate 1-naphthol or hydroxylate carbaryl. The dog canconjugate naphthol, and appears to conjugate carbaryl directly.” The latter statement may havereferred to the three unidentified 14C-naphthyl peaks, labeled E, F and H in this study (but notcorresponding to those in Knaak et al. [1965]), though this is not explicitly stated.

While it may be true, as stated in this study, that dogs metabolize carbaryl differentlythan rats (or humans, for which there are even less data), and may excrete more of the naphthylgroup in the feces, the usefulness of this study was limited by its small scope. Very few animalswere used (understandable in view of the species) and the metabolites from an appreciablefraction of the dose (most prominently, from the large fecal fraction) were not characterized. Inthe absence of a more contemporary dog study, it cannot be used to disqualify this species as alaboratory subject in the characterization of human risk from carbaryl.

This open literature article was considered to be supplemental.

31

^^^^^^^^^^^^^^^^^^^^

Rickard and Dorough (1984) investigated the possibility that the N-nitroso derivatives ofcarbamate pesticides could be formed under the acidic conditions of the stomach. In the in vivoexperiments, female Sprague-Dawley rats and Hartley guinea pigs were treated by gavage with14C-carbofuran or 14C-carbaryl and sodium nitrite (controls consisted of animals treated withcarbamate alone). The stomach contents were removed from the animals, processed andanalyzed by two-dimensional thin layer chromatography using nitrosocarbamate standards. Invitro experiments were conducted by incubating the sodium nitrite and radiolabeled carbamateswith stomach contents.

Guinea pigs formed nitrosocarbamates more readily than rats: 1.54% of the carbaryldose and 0.65% of the carbofuran dose were detected as the N-nitroso derivative in guinea pigsvs. 0.02% and 0.03% in the rat, respectively. When the incubations were carried out in vitrousing isolated stomach contents, 37.4% of the carbaryl dose and 18.9% of the carbofuran dosewere detected as the N-nitroso derivative in guinea pigs vs. 0.57% and 0.31% in the rat,respectively. This species difference was attributed to the lower pH of the guinea pig stomach(1.2-1.6) vs. the pH of the rat stomach (3-5), a conclusion which was supported by anexperiment in which the incubation with carbaryl was performed after the pH of the rat stomachwas artificially lowered with HCl or acetic acid. As the guinea pig stomach pH approximates thatof the human, this supports the possibility that nitrosocarbamates may be formed readily in thehuman stomach. The low nitrosocarbamate in vivo yields in either species were considered toreflect the instability of the derivatives, as well as the rapid absorption of both the parentcompound and the derivative.

The toxicologic significance of nitrosocarbaryl formation is not clear. This open literaturearticle was considered to be supplemental.

B. ACUTE TOXICITY (including ACUTE NEUROTOXICITY)

1. OverviewThe acute toxicity of carbaryl results from its ability to carbamylate, and thus inhibit, acetylcholinesterase (AChE) at synapses and neuromuscular junctions. Resulting local accumulationsof acetylcholine (ACh) generate cholinergic effects, including tremors, sluggishness, epigastricpain, blurred vision, nausea, sweating, lassitude, salivation, piloerection and lacrimation. Thelower LD50 reported for the intraperitoneal route than for the oral route in rodent studies impliesthat hepatic (or possibly gastrointestinal) metabolism and excretion plays an importantmediating role in the organismal response to carbaryl. The critical LOEL for oral toxicity was 1mg/kg, based on cholinergic effects in rats at that dose in a developmental neurotoxicity study(Robinson and Broxup, 1997; summarized in section III.H). Benchmark dose analysis was usedto arrive at an oral LED10 of 0.25 mg/kg. The critical LOEL for inhalation toxicity was 10 mg/m3,based on inhibition of brain cholinesterase activity at that dose in rats after a 3-hr exposure(Weinberg, 2008). Benchmark dose analysis was used to arrive at an inhalation LED10 of 5.5mg/m3, equivalent to an internal dose of 0.66 mg/kg assuming a default breathing rate of 0.96m3/kg/day. According to Baron (1991), only one human death, a suicide, had beenunambiguously tied to carbaryl ingestion by that time. Even in that case, the mortality may haveresulted from use of antidotal 2-PAM. A detailed medical account of a near suicide consideredthe possibility that carbaryl could have long-term neuropathic sequelae in humans similar tothose seen for organophosphates (Dickoff et al., 1987). The reported effects resulting from anextended accidental exposure in an older male support this notion (Branch and Jacqz, 1986).

32

Nonetheless, owing to the instability of the carbamate-AChE bond, recovery from acute effectsis expected in most cases when exposures are low or moderate.

2. Human exposuresBaron (1991) reviewed several experimental studies of systemic carbaryl exposures in humans.No effects were observed in one acute oral study in men at doses as high as 2 mg/kg. Inanother study, a scientist investigating possible antihelmintic properties of carbaryl, ingestedapproximately 2.8 mg/kg (250 mg total). Epigastric pain followed by profuse sweating beganafter 20 minutes, followed by lassitude and vomiting. Recovery was evident by one hour (3 mgof atropine were ingested by that time), and complete by 2 hours.

Baron described a similar incident as follows: “A scientist ingested, on an emptystomach, a suspension containing about 420 mg of carbaryl (5.45 mg/kg). (He had previouslytaken larger doses about an hour after a meal without any resulting illness.) No symptomsappeared for 80 min. After 85 min, he noticed a slight change in vision lasting for 15-20 min.After 90 min, he began to feel nauseated and lightheaded; 2 mg of atropine helped, but thesymptoms returned. By 17 min, after the onset of symptoms, he had taken 4.8 mg of atropine,despite which he began to sweat very profusely. Hyperperistalsis developed (with little pain).Nausea persisted for about 2 hr, but without vomiting or diarrhea. He experienced a profoundsense of weakness and preferred to remain perfectly still, but had no difficulty in breathing. Thesensorium remained completely clear, and he was able to answer questions readily andcorrectly. Symptoms were maximal about 2 hr after their onset, at which time the pulse rate was64 per minute (decreased from the subject’s normal resting rate of 70), and the respiratory ratewas 18 per minute. During the entire course of poisoning, no miosis, excess lacrimation orsalivation, or rales were observed. Definite improvement, including some increase in strength,appeared a little less than 3 hr after the onset of symptoms, and recovery was nearly complete4 hr after onset.”

Finally, Baron cites a NIOSH study in which two workers exposed to airborne carbarylfor two workdays at a concentration of 50 mg/m3 experienced no signs of intoxication.

^^^^^^^^^^^^^^^^^^^^

Branch and Jacqz (1986) described the toxic sequelae in a 75-year old man exposedaccidentally, but over a prolonged period, to carbaryl. Symptomology ranged from acute tochronic. The basement of the man’s home was subjected to six monthly treatments with a 10%preparation of Sevin dust to combat fleas. (According to the report, this was inconsistent withthe standard recommendation that a 2% preparation be used under these circumstances.) Theair conditioner, which was located in the basement, dispersed the carbaryl throughout thehouse.

The subject developed influenza-like symptoms within 3 days of initial exposure, andheadache, malaise, epigastric discomfort and muscle spasms on the fifth day. Progression ofthe symptoms, now including weight loss, occurred over the following month. An increase insymptom severity - severe spasms (at one point during the 6-month period requiringhospitalization), pressure headaches, rhinorrhea, tinnitus, vertigo, mild ataxia, muscle weaknessand muscle fasciculations - was noted after the second monthly treatment. The subject becameconcerned that dementia might be developing.

The cause of the symptoms was not identified until 8 months of continued exposure,over which there was progressive symptomology. Blood studies, initiated following a firstattempt to clean up the house at 8 months, revealed plasma cholinesterase levels at 64% of a“normal” value, confirming exposure to a cholinesterase inhibitor. RBC cholinesterase activityappeared normal.

5 Athetosis: "a derangement marked by ceaseless occurrence of slow, sinuous, writhingmovements, especially severe in the hands, and performed involuntarily" (Dorland’s Illustrated Medical

33

The symptoms persisted or worsened despite two attempts to clean the house. Lowabdominal discomfort led to the development of bilateral inguinal hernias, which were correctedfollowing hospital admission at 10 months. Plasma cholinesterase levels returned to normalwithin two days of this hospitalization, accompanied by symptomatic improvement, though thesurgeon was concerned for the apparent fragility of his tissues.

The subject moved to a motel following the surgery. His symptoms remained improved,though he experienced headache, nasal congestion and lacrimation upon home visits. Anirregular pulse at one month post discharge led to readmission to the hospital with sinusbradycardia accompanied by multiple ventricular ectopic beats, low plasma cholinesterase andmild weakness. Once again, symptomology improved during the hospitalization. The subjectthen moved to a new home, experiencing a marked improvement of his symptoms, though hissleep pattern, which was accompanied by headache, tinnitius and confusion, remained alteredduring the following two years. A relocation to yet another home witnessed abatement of mostsymptoms. However, neuropathy (referred to as a “glove-and-stocking peripheral neuropathy”)became more severe. This complication worsened over the following 15 months. Tomographyrevealed progressive dilation of the cerebral ventricles indicative of reduced cerebral function.

The authors state that the progressive, but non-specific, neurologic dysfunction that theydescribed in this subject may be indicative of a wider clinical problem.

^^^^^^^^^^^^^^^^^^^^

Dickoff et al. (1987) described a case in which a 23-year old man purposely swallowed 100 mlof Ortho-Liquid-Sevin (27% carbaryl in water), equivalent to a dose of ~500 mg/kg body weight.The same individual had consumed an unknown quantity of boric acid on the same day and a“small amount” of dicumarol rat poison the day before. The observed effects were attributed tothe very high carbaryl exposure (i.e., comparable to the rodent LD50). The following observationswere recorded (this list is largely quoted from the manuscript):

(1) found comatose 3 hr post carbaryl ingestion; (2) emergency room parameters, Day 0: coma, excessive salivation, miosis (1.5 mm

pupils [nonreactive]), rhythmic asynchronous eyelid twitches / fasciculations, spontaneousroving eye movements, corneal reflexes present, flaccid tone, pulmonary edema, diarrhea,incontinence, 70 mm Hg systolic blood pressure, 100/min heart rate, 34°C body temperature(returned to normal by 12 hr), 7.13 arterial blood pH, 50 mm Hg PCO2, 54 mm Hg PO2, intubationfor breathing and profuse bronchial secretion control, unresponsive to voice or pain, nospontaneous limb movement, tendon reflexes normal, ankle clonus but no plantar response,serum chemistries normal, brain CT normal, urine and blood toxicologic parameters normal,acute muscarinic toxicity resolved by 12 hr;

(3) emergency room parameters, Day 1: responsive to name, could blink, moved eyesand limbs, intubation discontinued, persistent dark brown heme negative urine, diarrhea for 48hr;

(4) Day 2: followed commands and conversed, abdominal cramping; (5) Day 3: prickling foot pains, progressing in 24 hr to legs and hands, whole blood ChE

4 U/ml (normal: 3-8 U/ml); (6) Day 5: diffuse pain, leg paralysis, absent tendon reflexes, occasional rapid

involuntary flexion of knees and hips, hand weakness, could not sit alone, glove and stockingsensory loss, pseudoathetotic 5 arm movements;

Dictionary, 26th Edition, 1985; W.B. Saunders Company; p. 134).

34

(7) Day 6: proximal right leg movements, CSF contained 2200 RBC/mm3, 20 WBC/mm3,65 mg% protein, normal conduction velocities with borderline amplitude of evoked compoundmuscle action potential in peroneal nerve, no voluntary motor units or only single unitrecruitment patterns in distal leg muscles, normal sensory responses, no abductor digiti quintiresponse decrement after repetitive ulnar nerve stimulation, symmetrically diffuse ERG;

(8) Week 3: impaired finger strength, inability to stand, plantar responses were flexor,persistent tenderness to distal palpation, marked impairment to pin and vibration below theknees, absent position sense in toes and impaired in ankles (normal in fingers);

(9) Week 5: bilateral footdrop, no volitional motor units below knees, pin sensationabsent in stocking distribution, toe position / vibration absent, diminished “CMAP” amplitudes intested nerves, normal conduction velocities in arms with slight slowing in legs, evoked sensorynerve responses showed low amplitudes, increased insertional activity in EMG, musclefibrillations and positive waves, periods of diffuse /symmetric slowing with EEG;

(10) Month 9: normal strength except for bilateral ankle / toe weakness, jerks elicited intriceps only, persistent loss of toe vibration / proprioception, pin and touch responses reduced tomidcalf, normal EEG.

The authors claim that one day after ingestion there were no signs of cholinergicoveractivity. They suspect that carbaryl induced a delayed polyneuropathy possibly similar tothe delayed syndrome known to occur with organophosphate exposures. It is not known ifbinding to neurotoxic esterase or the subsequent “aging” reaction was involved in this case.

35

3. Laboratory animal studiesLD50, LC50 and primary irritation data for carbaryl and for various end-product formulationscontaining carbaryl as the only active ingredient are listed in Tables III.2a and III.2b.

Table III-2a. The acute toxicity and primary irritation properties of technical grade carbaryl inmultiple species

SpeciesToxicityCategory LD50 or LC50 References

Oral LD50Rat, MRat, FRat, FMouse, M/FMouse, FRabbit (sex not reported)Guinea pig (sex not reported)Dog (sex not reported)Cat (sex not reported)Swine (sex not reported)Deer (sex not reported)Monkey (sex not reported)

IIIIIIIIIIIIIIIIIIIIIIIIIIII

233-840 mg/kg246-610 mg/kg

437.5 mg/kg108-650 mg/kg

515 mg/kg710 mg/kg280 mg/kg

250-795 mg/kg125-250 mg/kg

1500-2000 mg/kg200-400 mg/kg>1000 mg/kg

a-ea-eidia

a,dddddd

Intraperitoneal LD50Rat, M-adultRat, M-weanling (23 days)

n/an/a

64 mg/kg48 mg/kg

ll

Dermal LD50Rat, M/FRabbit, M/F

IIIIII

>2000 - >5000 mg/kg>2000 mg/kg

db,f

Inhalation LC50Rat, M/F - 4 hoursRat, M/F - 4 hours

IIIIII

0.873 mg/L2.50 mg/L

gh

Eye irritationRabbit IV b

Dermal irritationRabbit IV b

Dermal sensitizationGuinea pig negative j,k

a Mellon Inst. (1957) b Union Carbide (1983a-d)c Union Carbide (1985) d Cranmer (1986) e Larson (1987d) f Larson (1987a) - As the test article, Carbaryl90DF, was “slightly moistened to make pasty”, itis assumed that the moistening agent was water.

g Holbert (1989)h Dudek (1985)i Rybakova (1966)j Larson (1987c)k USEPA (2002a)l Brodeur and DuBois (1963)

36

Table III-2b The acute oral toxicity of carbaryl formulations in the rat

SpeciesTox.

Categ. LD50 or LC50 References

Oral LD505% Sevin Dust / rat7.5% Sevin Dust / rat50% wettable powder / rat13% emulsifiable. conc. / ratParid Bomb Plus (2.5% CL) / rat Sevin FR (40% CL) / ratSevin XLR (43% CL) / ratSevin 80 (80% CL) / ratSevin 50 MC (50% CL) / rat Sevin, 20% Bait / ratCC 12152 (SX-1400) (13.5% CL) / ratSevin 10 Dust (10% CL) / ratSevin 4F (42.3% CL) / ratSevin 4-Oil (47% CL) / ratSevin Brand XLR Plus (43.1% CL) / ratSevimol Brand 4 (40.5% CL) / rat Sevin Brand XLR Plus (44.3% CL) / ratAdams Flea & Tick Dust II (12.5% CL) / ratSevin 4-Oil (47.3% CL) / rat Sevimol (40.3% CL) / ratSevin Brand Granular Carbaryl Insecticide(6.3% CL) / ratMS9-558 (13% CL) / rat

IIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIII

III

4.49 g/kg (sex not stated)2.00 g/kg (sex not stated)0.23 g/kg (M)0.71 g/kg (M)>1.5 g/kg (M/F)750 mg/kg (M); 527 mg/kg (F)642 mg/kg (M); 472 mg/kg (F)406 mg/kg (M); 203 mg/kg (F)1070 mg/kg (M); 406 mg/kg (F)3.25 g/kg (M/F) 1.15 g/kg (M); 1.05 g/kg (F)2.9 g/kg (M); 1.6 g/kg (F)945.2 mg/kg (M); 1031.3 mg/kg (F)963.1 mg/kg (M); 473.3 mg/kg (F)486 mg/kg (M); 251 mg/kg (F)1180.9 mg/kg (M); 473.3 mg/kg (F)867 mg/kg (M); 575 mg/kg (F)1853 mg/kg (M); 1718 mg/kg (F)734.5 mg/kg (F)353.6 mg/kg (F)3310 mg/kg (M); 2330 mg/kg (F)

2230 mg/kg (M); 695 mg/kg (F)

aabbcdefghijklmnopqrs

ta Myers and Homan (1978) b Mellon Inst. (1957)c Biosearch, Inc. (1980) d Weatherhostz (1982) e Myers (1983a)f Myers (1983b)g Myers (1985)h Field (1980) i Fukuda (1983)j Duke (1982)

k Kuhn (1991a) l Kuhn (1991b) m Kuhn (1991c)

n Kuhn (1991d) o Kuhn (1991e) p Mitchell (1991) q Kuhn (1992a)r Kuhn (1992b) s Myers (1987) t Kuhn (1991f)

37

Moser (2007) investigated the effects of a single gavage dose of carbaryl on cholinesteraseactivity (brain and RBC) and motor activity in adult (92 days) and young (postnatal [pnd] days 11and 17) male Long-Evans hooded rats. The doses were 0 (corn oil vehicle), 3, 7.5, 15 and 30mg/kg body weight. ChE assays from tissue samples were performed 40 minutes after dosing,with special care taken to minimize carbaryl dissociation from the enzyme during the radiometricprocedure. Motor activity, a measure of neurotoxicity, was gauged in the pnd17 rats only. Thiswas done 15 minutes after dosing using a single 20-minute activity session conducted in afigure-eight chamber. The results of the pnd17 motor activity assays were compared topreviously collected data in adult animals. The number of animals examined per dose wasbased on the expected variability of the ChE and neurotoxicity endpoints in young and adultrats. Thus for adults, 6 animals per dose were used, so that a statistically significant 10%change in enzyme activity could be detected. Eight animals per dose were used for the pnd11animals due to the higher enzyme variability at the younger age. For the pnd17 animals, 10animals per dose were tested because the neurotoxicity assays were known to be more variablethan the ChE assays - thus a statistically significant 30% change in motor activity would bedetected by this number of animals.

Neither deaths nor severe toxicity were noted during the very short time period of thisstudy (40 minutes). Brain ChE from pnd11 animals was more sensitive to inhibition by carbarylthan the equivalent enzyme from pnd17 or adult animals. Thus for the pnd11 animals, activitiesat all doses were lower than controls by statistically significant margins, precluding assignmentof a NOEL for brain ChE inhibition in this study (Table III-3). Statistically significant brain ChEinhibition in pnd17 and adult animals was noted at 7.5 mg/kg and above, though it is noted thatactivities were lower than controls at 3 mg/kg by non-statistically significant margins. LED10(ED10) values for brain ChE inhibition in pnd11, pnd17 and adult animals, calculated by thestudy statistician (W. Setzer) using an exponential algorithm, were 1.14 (1.46), 2.37 (3.00) and2.03 (2.63) mg/kg, respectively. Parallel LED10 (ED10) values for RBC ChE inhibition in pnd11,pnd17 and adult animals were 0.78 (1.11), 1.05 (1.41) and 0.73 (0.96) mg/kg, respectively. Thepnd11 LED10 value for brain ChE inhibition, 1.14 mg/kg [rounded to 1.1 mg/kg], was used inUSEPA's Reregistration Eligibility Decision document to estimate acute risk from carbarylexposure (USEPA, 2007a).

Statistically significant decreases in motor activity were noted at the high dose only inthe pnd17 animals. The motor activity data for adult animals from a previous study suggestedthat adults were somewhat more sensitive to carbaryl than pnd17 animals with respect to thisparameter.

As this was not a FIFRA-guideline study, it was considered to be supplemental.

38

Table III-3. Brain and RBC cholinesterase activities, motor activities and ED10 and LED10 values following a single gavage dose inmale Long-Evans rats (Moser, 2007)

Carbaryl, mg/kg

0 3 7.5 15 30 LED10 a ED10 a

Brain ChE b

Pnd 11 (n=8) 3.70±0.32100±9

3.00±0.40 **80±11

2.38±0.29 **64±8

1.89±0.30 **51±8

1.60±0.27 **43±7

1.14 1.46

Pnd 17 (n=10) e 4.99±0.33100±7

4.55±0.4491±9

3.77±0.52 **76±11

3.26±0.31 **65±6

2.64±0.48 **53±10

2.37 3.00

Adult (n=6) 6.38±0.58100±9

5.86±0.6792±11

4.76±0.27 **75±4

4.01±0.60 **63±9

3.25±0.29 **51±5

2.03 2.63

RBC ChE c

Pnd 11 (n=8) 0.64±0.15100±23

0.50±0.1978±29

0.34±0.10 **53±16

0.23±0.06 **37±10

0.17±0.05 **27±7

0.78 1.11

Pnd 17 (n=10) 0.69±0.14100±20

0.57±0.1484±21

0.37±0.11 **55±16

0.31±0.06 **45±8

0.20±0.09 **29±13

1.05 1.41

Adult (n=6) 0.61±0.05100±8

0.39±0.05 **64±8

0.30±0.03 **50±5

0.21±0.05 **34±8

0.14±0.08 **24±13

0.73 0.96

Motor activity d

Pnd 17 (n=10) 114.6±37.0100±32

94.6±33.783±30

113.4±40.199±35

88.0±30.577±27

56.6±35.3 **49±31

nd nd

Abbreviation: nd, not determined**, p#0.01, Dunnett's parametric t test (performed by DPR)a LED10 and ED10 values, which are expressed as mg/kg, were calculated by the study author using an exponential algorithm.

39

b Brain cholinesterase activities are expressed both in units of µm ACh hydrolyzed / min / mg protein andin percent of concurrent controls.c RBC cholinesterase activities are expressed both in units of µm ACh hydrolyzed / min / ml RBCs and inpercent of concurrent controls.d Motor activities are expressed as total counts per 20-minute test period.e The only exceptions with regard to the n value for pnd 17 rats were the 0 and 15 mg/kg brain ChE dosegroups, for which n=9.

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In a rangefinding acute toxicity study, Brooks and Broxup (1995a) administered carbaryl(99.1%) by gavage to 2 rats/sex/dose (Sprague Dawley) at 10, 50, 100, 250, 500 or 1000 mg/kg(no control group). The vehicle was 0.5% (w/v) carboxymethylcellulose / 0.1% Tween 80 (10ml/kg). Dosing was followed by a 3-day observation period for clinical signs and mortality. Bodyweights were recorded on days 0, 1 and 3. Necropsies were not performed. Physical examswere performed pre-dose, at 0.5, 1, 2, 4 and 8 hr post-dose, and on days 1, 2 and 3.

At 1000 mg/kg all animals were dead within 24 hr. At 500 mg/kg, 1/2 males and 2/2females were dead within 24 hr. All animals survived at 250 mg/kg. Within 30 minutes in bothsexes, all rats at $50 mg/kg exhibited slight to severe salivation and tremors of head, bodyand/or limbs. Lacrimation, periorbital staining, urogenital staining, decreased activity, decreasedrespiration rate, abnormal breathing sounds and weakness were seen in some or all groups at$50 mg/kg. With the exception of staining, decreased activity and weakness, many of the signswere no longer observed 1 day after dosing. Weight losses were observed at all doses >10mg/kg.

A conditional NOEL of 10 mg/kg was established, based on clinical signs at 50 mg/kgand above. However, the low number of animals and limited observational time (3 days)diminished the reliability and regulatory importance of this value. This study was considered tobe supplemental.

In a follow-up study designed to determine the time to peak effects after a single oral dose,Brooks and Broxup (1995b) treated Sprague-Dawley rats by gavage with technical gradecarbaryl (99.1%). The doses were 0, 10, 50 or 125 mg/kg. As before, the vehicle was 0.5% (w/v)carboxymethylcellulose / 0.1% Tween 80 (10 ml/kg). Three animals/sex/dose were included inthe behavioral phase, which consisted of an abbreviated functional observational battery(locomotor activity, gait, tremor, twitches, convulsions, behavior, respiratory rate, lacrimation,salivation, staining and diarrhea) conducted at 0.5, 1, 2, 4, 8 and 24 hr (termination). Wholeblood, plasma and brain cholinesterase determinations were done at termination for theseanimals. An additional 15 animals/sex/dose were included in the cholinesterase phase (wholeblood, plasma and brain enzymes), with 3/sex/dose terminated at 0.5, 1, 2, 4 or 8 hr. RBC andplasma cholinesterase levels were also determined pre-dose.

Except for one 10 mg/kg male exhibiting muzzle/urogenital staining at 0.5 hr, FOBchanges and/or clinical signs were seen only at 50 and 125 mg/kg. FOB changes at all doselevels, including tremors and autonomic signs, exhibited a time to peak effect in the 0.5-1 hrrange, generally lessening after that time. A behavioral NOEL could not be assigned.

Brain cholinesterase activities showed marked inhibition at 0.5 hr (activities were 46%**,23%** and 18%** of concurrent controls at increasing doses in males, 54%**, 24%** and 22%**of controls in females) and 1 hr (males 68%**, 25%** and 22%** of controls; females: 64%**,23%** and 16%**; p<0.01, Dunnett’s test), declining steadily thereafter, though inhibition wasstill present after 24 hr at 125 mg/kg in both sexes at the high dose (77% and 65%** ofcontrols). A similar pattern was evident for whole blood cholinesterase activities, though theextent of the inhibition was somewhat less than for brain. Plasma cholinesterase activities weremarkedly inhibited at 0.5 and 1 hr (males, 0.5 hr: 64%*, 24%** and 19%** of controls; females,0.5 hr: 62%, 29%* and 31%*; males, 1 hr: 68%*, 27%** and 17%**; females, 1 hr: 71%*, 25%**and 11%). Substantial recovery had occurred by 24 hr except at the high dose where male andfemale activities were 59%* and 46%** of controls.

Based on the clear inhibition of all cholinesterases (including brain cholinesterase) at 10mg/kg, this dose was designated as a LOEL for this study. This study was deemedsupplemental.

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A third study in this series was designed determine the time course of cholinesterase inhibitionin rats after acute oral exposure to carbaryl (Brooks and Broxup [1995c]). Carbaryl (99.1%) wasgiven by oral gavage to Sprague-Dawley rats at doses of 0, 10, 30 or 90 mg/kg. The vehiclewas 0.5% (w/v) carboxymethylcellulose / 0.1% Tween 80 (10 ml/kg). There were 24rats/sex/dose, with 6/sex/dose sacrificed at 1, 8, 24 or 48 hr after dosing. Blood, brain andseveral brain regions were processed for determination of cholinesterase activity. Whole bloodand plasma activities were measured and RBC activity was calculated from thesemeasurements after determining hematocrits. “Whole” brain enzyme measurements wereconducted using the left hemisphere. Brain regional measurements (frontal cortex,hippocampus, cerebellum and caudate/putamen) came from the right hemisphere. Clinical signswere also monitored.

No clinical signs were reported at 10 mg/kg. At 30 and 90 mg/kg signs included tremors(slight at 30, moderate to severe at 90 mg/kg), salivation, staining of fur and wetness in variousareas on the day of treatment, with an occasional clinical siting at 90 mg/kg up to 2 days (studytermination).

Cholinesterase activities were statistically lower in all samples from the 30 and 90 mg/kggroups and in most samples at 10 mg/kg. By 8 hr all samples at 10 mg/kg were comparable tocontrols. By 24 hr all samples at 30 mg/kg were comparable to controls. By 48 hr, all samples atall doses were comparable to controls. Brain regional assays did not show qualitativedifferences. Based on the inhibition of all cholinesterases at 1 hr at 10 mg/kg (including thevarious brain cholinesterases, which showed activities of 57%-73% of concurrent controls atthat time), this dose was designated as a LOEL for this study.

This study was deemed supplemental.

A fourth study in the series was designed to study the behavioral and possibleneuromorphologic effects of acute gavage exposure to carbaryl in Sprague-Dawley rats (Brookset al. [1995]). Carbaryl (99.1%) was given in a single oral dose to 12 rats/sex/dose at 0, 10, 50or 125 mg/kg using 0.5% (w/v) carboxymethylcellulose / 0.1% Tween 80 (10 ml/kg) as thevehicle. Examinations for mortality and clinical signs were performed daily. Body weights andfood intake were assessed weekly. Functional observational batteries (FOB) and motor activityassessments were performed both prior to and after dosing on day 0 (0.5 hr after for the FOBand 50-90 min for the motor activity assessment, to correlate with the time of peak effectdocumented in Brooks and Broxup [1995b]), and on days 7 and 14. At study termination on day15, 6/sex/group were processed for neuropathology examinations. The remaining 6/sex/groupwere necropsied.

There were no deaths. Clinical signs, noted in females at 50 mg/kg and in both sexes at125 mg/kg, were dominated by observations of fur staining and ocular signs. Mid and high dosemales exhibited reduced body weight gains during the first week, but appeared to compensateduring the second week (mean male weight gains in grams, week 1, at ascending doses: 41.8,40.7, 32.4*, 13.0**; week 2: 35.6, 37.5, 34.1, 41.3; *, **p<0.05, 0.01). High dose femalesexhibited reduced body weight gains during the first week, but also appeared to compensateduring the second week (mean female weight gains in grams, week 1: 16.5, 16.5, 13.0, 9.6;week 2: 13.3, 15.2, 13.5, 22.9*; *p<0.05). Food intake was decreased during week 1 (meanmale intake in grams/rat at ascending doses, week 1: 183.9, 203.7, 181.5, 148.4**; week 2:204.8, 214.3, 195.9, 188.1; mean female intake, week 1: 132.5, 138.9, 127.2, 109.3**; week 2:135.6, 145.6, 137.5, 141.7; **, p<0.01).

FOB analysis revealed effects in both sexes at 50 and 125 mg/kg on day 0. In manyinstances dose responsiveness was evident with respect to severity and incidence, with mostobservations achieving statistical significance. These included [ incidence of salivation and / or

42

wet muzzle, [ incidence of tremors, ataxic gait / overall gait incapacity, \ locomotor activity,arousal and # of rears, [ positional passivity, \ extensor thrust, tail and toe pinch responses,impaired visual placing response, \ urination and defecation in males, \ vocalization upon cageremoval in females, [ auricular startle response (high dose), [ incidence of males lying onventral surface (high dose), \ fore and hind grip strength (high dose), [ hindlimb splay (males,high dose), and \ body temperature. These effects had largely abated by days 7 and 14.

There were marked decreases in motor activity counts (>75%) over 60 minutes in bothsexes at 50 and 125 mg/kg on day 0 (Table III-4). Motor activity counts at 10 mg/kg were alsoslightly lower than controls (males: 177.2* vs. 221.7; females: 314.3* vs. 393.8; p<0.05).However, the study authors discounted the possibility that the 10 mg/kg observation wastreatment induced, citing the predose variability, the lack of similar findings in the concurrentFOB, and the fact that the values were within the historical control range for the laboratory(however, only the male historical control range of 130-361 counts was presented). On the otherhand, it is likely that brain cholinesterase inhibition was present at this dose - the same authorshad observed marked inhibition at 10 mg/kg at 0.5 hr (the time to peak effect) in one of theprevious studies in this series (Brooks and Broxup [1995b]). In addition, (1) the effect wasnoted in both sexes, (2) the direction of the motor activity change (i.e., a lowered activity in thepresence of 10 mg/kg carbaryl) was consistent with the motor activity and FOB observations atthe higher doses, and (3) the pattern of motor activity observations through the hour-long assayin both sexes, recorded in 10-minute intervals, indicated a depressive effect of carbaryl early inthe hour (when the animals were much more active). The extent of the carbaryl effectdecreased later in the hour, when the activity of all of the animals (controls and dosed) haddeclined precipitously. Thus the decrease in motor activity counts at 10 mg/kg was consideredtoxicologically significant for the purposes of risk assessment.

Necropsies and histopathologic analyses did not yield carbaryl-related effects. This wasalso true for the brain weight and size determinations performed at study termination.

A NOEL was not determined for this study. The LOEL was set at 10 mg/kg based on areduction in motor activity counts at that dose. The study was considered acceptable by FIFRAguidelines.

Table III-4. The impact of carbaryl exposure (acute, oral gavage) on motor activity a in Sprague-Dawley rats; 1-hr mean data (Brooks et al., [1995])

Males Females

0 mg/kg 10 mg/kg 50 mg/kg 125 mg/kg 0 mg/kg 10 mg/kg 50 mg/kg 125 mg/kg

Pre-study

255.3±87.6 303.2±92.8 294.1±104.8 252.0±85.3 298.8±112.8 272.4±66.6 316.9±140.3 250.5±97.9

Day 0 221.7±51.3 177.2±59*** 53.7±32.4*** 35.8±23.7*** 393.8±127.6 314.3±101.6# 36.9±31.4### 47.8±65.3###

Day 7 217.9±57.0 281.3±57.7 322.8±139.0 193.3±88.1 425.9±107.2 391.8±143.6 503.8±161.7 298.4±138.4

Day 14 246.3±80.1 293.6±98.7 347.7±153.6 227.5±94.5 452.9±132.2 406.3±115.5 451.1±131.4 362.3±158.9

***: p<0.001, t-test, linear constructed variable#, ###: p<0.05, 0.001, Wilcoxon, linear constructed variablea Motor activity was determined in a “Figure 8 enclosure” based on interruption of a light beam. The 1-hrsessions were recorded by a microcomputer in 30 successive 2-min intervals. The mean number ofcounts/hr ± the standard deviation is expressed in this table.

^^^^^^^^^^^^^^^^^^^^

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Beyrouty (1992a) examined the time to peak effect in Sprague-Dawley male rats, 2/dose, froman acute gavage dose of carbaryl (98% purity). Doses were 0 (10 ml/kg aqueous 0.5%carboxymethylcellulose / 0.1% Tween 80), 25, 80 or 250 mg/kg. There was no analysis of thetest material. Animals were observed for a 7-day period, including body weight measurements.An abbreviated FOB was conducted at 0.5, 1, 1.5, 2, 3, 4, 5, 6, 7 and 8 hr post dose.

There were no deaths, despite the fact that the high dose approached or exceeded theLD50 for this compound. High dose animals showed decreased arousal and locomotor activity,with the largest effect at 1-1.5 hr. They also exhibited incapacitated gait, tremors, salivation,lacrimation (beginning @ 4 hr), urinary staining (beginning @ 4 hr), and reduced respiration.Mid dose animals showed decreased locomotor activity (greatest effect, 0.5-3 hr), decreasedarousal (greatest effect, 0.5-1 hr), incapacitated gait, tremors, salivation and reducedrespiration. Effects on body weight were seen at 80 and 250 mg/kg. No clear effects weredetected at the low dose. The estimated time to peak effect was 0.5-1.5 hr. The NOEL was setat 25 mg/kg. This was a non-FIFRA-guideline study.

In a more extensive study, Beyrouty (1992b) examined the effects of carbaryl after acute oraladministration to Sprague-Dawley rats. Twelve males per dose were treated with a singlegavage dose at 0 (10 ml/kg aqueous 0.5% carboxymethylcellulose / 0.1% Tween 80), 12.5, 40or 125 mg/kg carbaryl (98% purity). There was no analysis of the test material. Twice dailyobservations for clinical signs and mortality were conducted. Body weights were determinedweekly. FOBs and motor activity evaluations were carried out pretest and on days 0 (day oftreatment), 1, 7 and 14. Histopathologic exams were conducted on brain and abnormal tissues.

There were no deaths during the 2-week course of the study. A 27 g loss of body weightat 125 mg/kg between days 0 and 1 resulted in significantly lower body weights on days 1 and 7(9.5% and 6%, respectively; p<0.01). Body weight effects were not apparent at the other doses.FOB analysis on day 0 showed the following effects at 125 mg/kg: tremors; gait incapacity;salivation; miosis; decreased locomotor activity, arousal and defecation; abnormal responses tosensory tests and others. Day 0 FOB effects at 40 mg/kg included tremors; salivation; anddecreased locomotor activity, arousal, toe/tail pinch and defecation. Defecation was alsostatistically reduced at 12.5 mg/kg on day 0 (# of fecal “boli” during a 2-min period in the day 0FOB: 1.9±1.4, 0.8±1.0*, 0.8±0.7*, 0.0±0.0***; *p<0.05; ***p<0.001). However, these data werevery hard to interpret in view of the short observation period. Forelimb and hindlimb gripstrength were reduced on day 0 at 125 mg/kg, with hindlimb grip strength also reduced at 40mg/kg. Foot splay was significantly increased in both dose groups on Day 0. Body temperaturewas reduced on day 0 for all dose groups (°C): 38.0±0.33, 37.3±0.99*, 34.9±0.53** and34.3±0.78** (*p<0.05; **p<0.01). There was, however, concern that the control bodytemperatures were inappropriately high, casting doubt on the apparent temperature loweringresponse at 12.5 mg/kg. Group mean total activity counts were lower at 40 and 125 mg/kg (209,207, 43.3*** and 23.7***; ***p<0.001). Total activity counts were still statistically depressed onday 1 at the high dose, though no significant differences remained by days 7 and 14.

Based on the FOB and decreased body temperature findings at 40 and 125 mg/kg, theLOEL was set at 40 mg/kg. The apparent effects on defecation and body temperature at 12.5mg/kg were not considered strong enough to establish a LOEL, though they were certainlyindicators that adverse effects could be detected at that dose in other studies. This study wasconsidered supplemental.

^^^^^^^^^^^^^^^^^^^^

In an open literature study, Moser et al. (1988) used the functional observational battery (FOB)to discern probable neurotoxic responses in Long-Evans hooded rats, 10/sex/dose, to a single

44

intraperitoneal dose of carbaryl . The carbaryl doses were 0 (vehicle control: 5% ethanol-5%Emulphor in saline), 3, 10 and 30 mg/kg. The effects of chlordimeform were also examined,though those results will not be summarized here. The FOB tests were run prior to dosing andat 0.5, 3, 24 and 48 hours post dose. The following parameters were examined: posture,palpebral closure, presence or absence of writhing, circling, biting or vocalizations, ease ofremoval / handling, observable signs (exopthalmus, crustiness around the eyes, piloerection,bite marks on tail or paws, missing toenails, body tone and emaciation), “cart top”measurements (latency to first step, number of rears [supported and unsupported], groomingepisodes, gait characteristics, arousal level, number of fecal boluses and urine pools), reflextesting (responses to approach of a pencil, a touch to the rump, finger snap, tail pinch), pupilcontraction to light, extensor thrust, limb rotation, degree of catalepsy, righting reflex, gripstrength, foot splay, body weight and rectal temperature. The entire exam required 6-8 minutesper rat.

Effects noted at both 10 and 30 mg/kg included the following (in both sexes unlessotherwise noted): decreased rearing, decreased arousal, home cage posture alteration,decreased removal difficulty (males only), convulsions, increased urination (females at highdose only), home cage palpebral closure (females at high dose only), pupil response, rightingreflex, decreased approach response (females at high dose only), decreased finger snapresponse (males at high dose only), decreased touch response, decreased tail pinch response,chewing motions, decreased rectal temperature and decreased body weight (females at highdose only). Effects noted at 30 mg/kg only included increased latency to first step (males only),abnormal fur appearance, decreased defecation, salivation, piloerection (males only), affectedgait, decreased forelimb grip strength (females only), palpebral closure at handling (males only),generalized tremors and catalepsy. For those parameters for which time data were reported, themost severe responses were noted at 0.5 and 3 hr post dose. There was limited evidence for aslight increase in unsupported rears in males at 3 mg/kg, though dose dependence was not inevidence. In the absence of other signs at that dose, this particular observation was consideredinadequate to determine a LOEL.

The acute NOEL was set at an intraperitoneal dose of 3 mg/kg, based on a plethora ofFOB observations at 10 mg/kg/day.

^^^^^^^^^^^^^^^^^^^^

Weinberg (2008) administered aerosolized carbaryl technical (99.8% purity) through nose-onlydevices to two separate cohorts of Crl:CD (SD) rats. Exposure was for a single 3-hr period using5 animals/sex/dose. In the first cohort, the animals were exposed at 0, 63, 121 or 247 mg/m3

(gravimetric analysis). The respective mean mass median aerodynamic diameters (geometricstandard deviations) for the exposed groups were 1.6 (2.15), 1.6 (2.18) and 1.7 (2.23) µm,respectively. In the second cohort, males were exposed to 0, 12, 29 or 55 mg/m3, with MMAD(GSD) values of 2.1 (2.25), 2.0 (2.19) and 2.0 (2.22) µm. The females in this cohort wereexposed to 0, 10, 27 or 65 mg/m3, with MMAD (GSD) values of 2.1 (1.92), 2.1 (2.28) and 2.0(2.22) µm, respectively. RBC and brain cholinesterase activities were determined immediatelyupon termination of exposure. According to the text of the study, precautions were taken tominimize dissociation of carbaryl from the enzyme during the assay. Gross necropsies werealso performed and brain weights determined at that time.

All animals survived the exposure period. Necropsies and brain weight determinationswere unremarkable. RBC and brain cholinesterase activities in the first cohort were reduced in astatistically significant, dose-dependent manner for both sexes in all exposure groups (p<0.01).Significant reductions were also noted at the mid and high doses in the second cohort (doseresponsiveness was not evident in the case of the RBC enzyme). Reductions at the low doses

45

did not achieve statistical significance, though they were suggestive of effects. A LOEL of 10mg/m3 (1.2 mg/kg for the 3-hr exposure using the default breathing rate of 0.96 m3/kg) wasassigned based on the inhibition of brain cholinesterase in females at the low dose in cohort #2.Benchmark dose analysis of these data using the power algorithm (power unrestriced) resultedin LED10 (ED10) values of 5.51 (13.29) mg/m3, equivalent to 0.66 (1.59) mg/kg (Appendix V).

This study was considered to be supplemental, as it was not performed according to aFIFRA guideline protocol.

Table III-x. RBC and brain cholinesterase activities after a 3-hr acute inhalation exposure tocarbaryl in rats (Weinberg, 2008)

Cohort 1:Carbaryl (mg/m3) - males Carbaryl (mg/m3) - females

0 63 121 247 0 63 121 247

RBC, U/L% of control

3708±856 2317±182**62.5%

1625±35**43.8%

1040±484**28.0%

4067±638 1551±620**38.1%

955±446**23.5%

831±460**20.4%

Brain, U/L% of control

47391±1293 36116±1298**76.2%

32512±3054**68.6%

23302±4390**49.2%

45767±2342 31991±4565**69.9%

23563±4773**51.5%

19861±2462**43.4%

**p<0.01 Cohort 2:

Carbaryl (mg/m3) - males Carbaryl (mg/m3) - females

0 12 29 55 0 10 27 65

RBC, U/L% of control

4212±616 3765±56789.4%

2931±402**69.6%

3463±198082.2%

4508±530 4296±63395.3%

3282±216**72.8%

3236±369**71.8%

Brain, U/L% of control

49920±2400 48515±222897.2%

41771±1295**83.7%

40133±1980**80.4%

51181±2414 47776±296693.3%

42833±1398**83.7%

40506±1533**79.1%

**p<0.01

46

C. SUBCHRONIC TOXICITY (including NEUROTOXICITY)

1. OverviewThree subchronic oral studies, in mice, rats and dogs, were available for analysis. As none ofthese studies was conducted according to FIFRA guidelines, each was consideredsupplemental. Neither the mouse or dog studies showed clear adverse effects. However,neurotoxic effects were observed in the rat with respect to maze performance, EEG readingsand brain cholinesterase activities. As the changes in maze performance were manifested soonafter the advent of dietary exposure, they were consistent with an acute effect. Three 4-weekrepeat dose dermal studies using 99.49%, 44.82% and 80.07% formulations were alsoconducted. Carbaryl inhibited both RBC and brain cholinesterases at a LOEL dose of 50mg/kg/day (99.49% and 80.07% formulations). Except for possible weight decrements and localirritation noted with the 99.49% formulation, there were no other effects.

Subchronic NOELs and LOELs are summarized in Table III-8.

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2. Laboratory animal studiesa. Oral exposureMice. Dange (1998) administered carbaryl (purity, 98.4%) in the diet to TSG p53 wild

type male mice for at least 28 days. Diets of 0, 160, 1000, 2000, 4000 or 8000 ppm were fed to10 mice per dose group in two different studies (0, 160, 1000 and 8000 ppm in one study, 0,2000 and 4000 ppm in the other). These corresponded to mean compound consumption levelsof 0, 35.7, 222.0, 424.4, 935.6 and 2107.3 mg/kg/day. All mice were necropsied on days 29 or30. Bodyweight, mortality, clinical signs and organ weights were determined, thoughhistopathology was not performed.

Neither deaths nor clinical signs were noted during the study. The 8000 ppm mice lost~14% of their initial body weight during the first study week (23.26 g at the outset vs. 20.16**grams after week 1 for the high dose animals; 22.84 g vs. 23.77 g for the controls; **p<0.01).These animals did not recover their bodyweights by the end of the study (21.63** g vs. 24.89 gin controls after week 4). At 4000 ppm, the mice also sustained bodyweight losses during thefirst week (21.54 g at the outset vs. 21.19** g after week 1 for the 4000 ppm animals; 21.63 gvs. 23.16 g for the controls). By study termination the weight differences between the controlsand 4000 ppm animals amounted to ~6%, though the differences were not statisticallysignificant. Food consumption was statistically increased at 8000 ppm during the second week(6.16** g/day vs. 4.97 g/day in controls) and at 4000 ppm during the first week (5.82* g/day vs.4.97 g/day in controls). The relative liver weights (compared to total bodyweight) were 6%*,12%* and 16%* higher than controls at 2000, 4000 and 8000 ppm. There were no discernibleeffects on absolute liver weight, however. Relative kidney weights were also slightly higher atthose doses, though statistical significance was not achieved. Necropsies did not revealtreatment-related abnormalities.

A conditional NOEL was set at 1000 ppm (222.0 mg/kg/day) based on the relative liverweight changes at 2000 ppm (424.4 mg/kg/day). However, since histopathology was not done, itis difficult to gauge the toxicologic significance of this change.

This study was considered to be supplemental.^^^^^^^^^^^^^^^^^^^^

Rats. Desi et al. (1974) examined the neurotoxicologic effects in male Wistar rats (Rstrain) of daily dietary exposure to carbaryl. The exposure period was up to 50 days. Anothercarbamate, Arprocarb, was also tested, though those data will not be summarized here. Thestated aim of the study was to provide information on (1) whether these compounds can beused safely over extended periods and (2) what the relationship is between cholinesteraseinhibition and the observed neurotoxicity.

Rats received carbaryl (Sevin 85 WP) through the feed, which was administered at 10 gof feed/day/100 g body weight in order to ensure precise dosing. The final carbaryl doses were10 and 20 mg active ingredient/kg/day. Animals were evaluated by means of: (1) T-mazeexperiments designed to determine the time to reach a goal and number of errors committed inthat process (Test #1: 8 rats/group, 50-day test, to see how carbaryl affects the rate that ratslearn how to negotiate the maze; Test #2: rats previously trained over a 15-day period tonegotiate the maze were subjected to a 50-day test, 8 rats/group, to see how the pesticideaffected the performance of the pre-learned task.); (2) EEG exams, which employed twofrontooccipital electrodes on unrestrained animals after the 50-day period; (3) cholinesterasedeterminations on blood and brain parts (cortical gray matter, white matter, brain stem,cerebellum), also performed after the 50-day period, with special precautions taken to preventdissociation of carbaryl from the enzyme.

During the first 2 weeks, both dose groups performed notably better in the mazes than

48

controls, achieving the goal 10-12 seconds faster at day 11 (p<0.05, for both groups). However,by day 25, there were no clear differences between treated animals and controls, a situationthat was maintained through the end of the study at day 50. A similar observation was made forerror frequency - while significantly fewer errors were made in both dose groups on day 11(p<0.001), all groups (including controls) declined to a minimum error frequency around day 22-24, followed by a general increase in error frequency in all groups after that point with no cleardifference between treated animals and controls.

If the animals were first trained in maze running for 15 days before the advent oftreatment, maze performance continued to improve somewhat in controls (maze time at the endof training = 7.9 sec; maze time at 50 days = ~5 sec). Low dose animals may have continued toimprove at a slightly higher rate than controls, though by 15 days feeding, controls and low doseanimals could not be distinguished, and by 50 days, low dose animals negotiated the maze withstatistically higher times than controls (~6 sec., vs. ~5 sec., p<0.02). On the other hand, highdose animals ceased the improvement with the advent of treatment. Their running times at days21 and 50, were statistically higher than controls (p<0.05 and p<0.02, respectively). Errorfrequencies were statistically higher in both groups following the advent of treatment.

Carbaryl increased the frequency of basal brain electrical activity in both dose groups.This was particularly true of the ( (theta) wave frequency, which was statistically increased overcontrols at both doses (p<0.01) and the $2 wave frequency, which was statistically increasedover controls at the high dose (p<0.01). Exposure to rhythmic light loading at 1.5, 5 or 11 Hz didnot change the EEG characteristics. However, “markedly accelerated electrical activity” wasseen in carbaryl-exposed animals at a stimulation rate of 18 Hz (though the data were notprovided in the report).

Animals exposed to 20 mg/kg/day carbaryl for 50 days registered statistically lowercholinesterase activities in all brain regions examined. Thus cortex, white matter, brain stem andcerebellum exhibited 60.5%, 85.8%, 56.3% and 60.9% of control activities. Animals exposed to10 mg/kg/day did not evidence statistically significant changes (though again, the data were notprovided in the report). Plasma and RBC cholinesterase activities in treated animals weresimilar to controls. Dose-dependent, statistically significant increases in protein content wereseen in all four brain regions.

The authors ascribed the increased learning ability detected in the first 2 weeks of mazetesting to “enhanced irritability” of the central nervous system. Their conviction that the CNSwas the main site of action was strengthened by the observation that “the animals were able tomove quickly even during [the] second period” (i.e., the period of decreased maze function).This was supported by the evidence that EEGs and brain cholinesterase activities were alsoaltered by carbaryl exposure.

A LOEL of 10 mg/kg/day was established in this study based on changes in mazefunction, EEG characteristics and brain cholinesterase activities at that dose. The rapidity inwhich maze performance changed as a function of exposure suggested an acute basis for theeffect. Such could not be said for the EEG and enzyme observations, which were made onlyafter 50 days of daily exposure.

This study was considered to be supplemental.^^^^^^^^^^^^^^^^^^^^

Dogs. Hamada (1991) studied the effects of carbaryl (purity, 99.3%), administered tobeagle dogs for 5 weeks by the dietary route. There were 6 dogs/sex/dose. Doses were 0, 20,45 and 125 ppm, corresponding to average systemic doses of 0, 0.59, 1.43 and 3.83 mg/kg/dayin males and 0, 0.64, 1.54 and 4.11 mg/kg/day in females.

There were neither deaths nor clinical signs throughout the study. Body weights, food

49

consumption, ophthalmoscopy, RBC cholinesterase activities (measurements done on days -11,-8, -5, 14 and 32), brain cholinesterase activities (measurements on days 37-39) and grosspathology appeared unaffected by exposure. Statistically significant depressions of plasmacholinesterase activities (measurements on days -11, -8, -5, 14 and 32) were detected in day 14males at the low and high doses (enzyme activities at increasing doses, in µM/ml, day 14: 8.9,7.3*, 8.1, 6.9*; *p#0.05). As there was no clear dose responsiveness, no sign of an effect infemales, no statistically significant effects at day 32, and the "inhibition" characteristics wereroughly shared by the same animals when measured on three separate occasions before thecommencement of dosing (eg., plasma ChE activities on day -8 were 9.1, 7.7, 8.6 and 8.3µM/ml), the depressions on day 14 were not sufficiently clear to be considered a definitefunction of carbaryl exposure. Even so, the possibility of inhibition, particularly at the high dose,was not definitively excluded.

As there were no adverse effects noted, the subchronic NOEL was set at >125 ppm (M:3.83 mg/kg/day; F: 4.11 mg/kg/day). Due to the short length of treatment, the limited parametersmeasured, the lack of histopathologic exams and the poor dose selection (i.e., too low), thisstudy was considered to be supplemental.

b. Dermal exposureRats. Austin (2002a) examined RBC and brain cholinesterase activities in Sprague-

Dawley rats, as well as local and systemic signs, during 4 weeks of daily dermal exposure (6-7hr/day, 5 days/wk) to carbaryl (99.49%). The test material, a slightly pink powder, was appliedunder gauze to moistened skin (~10% of the body surface area) at doses of 0, 20, 50 or 100mg/kg/day. There were 10 animals/sex/group. They were observed twice daily for mortality andmoribundity, while weekly observations (including on the first day of treatment) were made forclinical signs and dermal irritation. RBC cholinesterase activities were measured before thedaily application on days -4, 1, 8, 15 and 22, and within 1 hr after dose removal on days 5, 12,19 and 26. Brain cholinesterase was determined in the right half of the brain following sacrificeon day 26.

All animals survived the treatment. There were no behavioral or morphologic signsattributed to carbaryl exposure. Mean body weight gain for high dose males was statisticallylower than controls for the day 5-12 period (weight gains at ascending doses, males, day 5-12:33, 35, 34, 24* g; *p#0.05). Decreased (though non-statistically significant) mean body weightgains in high dose animals were also noted over the time periods on either side of the day 5-12period (i.e., days -3-5 and 12-19). Whether or not the statistically increased weight gain in middose males for the day 19-26 period (19, 20, 26*, 23 g; *p#0.05) was treatment related was notclear, though the lack of dose responsiveness is noted. Dermal irritation observations revealeda slight atonia (impairment of elasticity) in 1/10 and 4/10 high dose males and females,respectively.

RBC cholinesterase activities at 50 and 100 mg/kg/day were lower than parallel controlsby statistically significant amounts in those samples taken within an hour of test article removalon days 5 (% & &) and 12 (% @ 100 mg/kg/day only, & @ 50 & 100 mg/kg/day). On day 19,statistically significant inhibition was registered at 100 mg/kg/day in females only, while on day26 no inhibition was noted in either sex (Table III-5). Regardless of sampling day, inhibitoryeffects noted after a 6-7 hr dosing period may be more a function of single, rather than multiple,exposures.

RBC cholinesterase inhibition was less apparent in those samples taken before the dailydosing, with statistically significant effects noted only in high dose males on days 8 and 22. Noinhibition was noted in females. Inhibition in the pre-daily dose samples, when it was detected,might represent a effect of multiple dosing rather than an acute effect.

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Brain cholinesterase activities measured on day 26 were 15% lower than controls inmales at 50 and 100 mg/kg/day and 24% lower than controls in females at 100 mg/kg/day(p<0.05). It was not clear if the brain effect was due to a single or a multiple exposure, sincesamples were taken only after a 6-7 hr dermal exposure period on day 26.

The systemic NOEL was 20 mg/kg/day based on the observed inhibition of brain andRBC cholinesterase activities at 50 mg/kg/day. The NOEL for local dermal effects was 50mg/kg/day, corresponding to an approximate dermal dose of 0.31 mg/cm2 (assuming a bodysurface area for a 200 g rat of 325 cm2 - Harkness and Wagner [1983]), based on the atonianoted at 100 mg/kg/day.

This study was considered to be supplemental.

51

Table III-5. RBC and brain cholinesterase activities in a 4-wk carbaryl repeat-dose dermal studyin Sprague-Dawley rats (Austin, 2002a)

Carbaryl dose, males (mg/kg) Carbaryl dose, females (mg/kg)

0 20 50 100 0 20 50 100

RBC, Umol/L - Pre-daily dose assays

Day -4 1283±82.3 1272±71.199%

1338±96.5104%

1305±91.8102%

1323±91.9 1302±96.998%

1300±131.498%

1299±90.598%

Day 1 1334±95.1 1373±124.9103%

1382±121.9104%

1326±102.299%

1410±80.6 1398±74.299%

1513±143.2107%

1405±123.6100%

Day 8 1136±82.2 1081±135.395%

1150±123.4101%

1012±51.3*89%

1075±81.5 1144±94.1106%

1125±186.9105%

1199±135.4112%

Day 15 1162±116.7 1183±133.5102%

1221±104.3105%

1194±103.3103%

1172±117.2 1146±87.198%

1252±77.7107%

1254±70.2107%

Day 22 1273±90.1 1304±150.9102%

1269±89.7100%

1113±85.6*87%

1362±92.4 1291±120.195%

1215±142.589%

1232±142.490%

RBC, Umol/L - Post-daily dose assays

Day 5 1281±99.0 1308±113.8102%

1122±63.2*88%

1089±79.4*85%

1339±120.5 1363±108.0102%

1165±116.4*87%

1172±177.4*88%

Day 12 941±111.4 918±114.198%

851±83.790%

740±92.9*79%

996±91.4 961±68.596%

801±111.7*80%

865±120.2*87%

Day 19 1199±142.3 1191±110.799%

1164±112.797%

1002±118.8*84%

1211±101.2 1330±97.3110%

1199±115.699%

1188±282.398%

Day 26 1266±123.7 1360±123.8107%

1280±146.1101%

1282±170.4101%

1465±133.2 1412±144.496%

1394±146.495%

1492±219.7102%

Brain, Umol/mg - Post-daily dose assays

Day 26 40±4.8 41±3.8103%

34±4.0*85%

34±7.1*85%

45±2.9 45±4.4100%

41±4.491%

34±6.0*76%

*p<0.05

In a continuation of the repeat-dose dermal studies done for this series, Austin (2002b) appliedSevin XLR Plus (44.82% carbaryl) to ~10% of the body surface of Sprague-Dawley rats,8/sex/group, at 0, 20, 50 or 100 µl/kg/day, 6-7 hr/day, 5 days/wk, for 4 weeks. Body weight,body weight change, food consumption and dermal irritation were evaluated and were negativefor treatment-related effects. RBC cholinesterase was measured before daily exposure on days1, 8, 15 and 22, and within 1 hr after dose removal on days 5, 12, 19 and 26. Braincholinesterase activity was not measured.

High dose females showed a 12% inhibition of RBC cholinesterase activity compared tocontrols (p#0.05) on days 5 and 12 after dosing, but not on days 19 and 26. Clear test article-induced inhibition was not detected in males.

The systemic and dermal irritation NOELs were >100 µl/mg/day. The RBCcholinesterase NOEL was not determined in light of the mildness and inconsistency of the

52

cholinesterase data.This study was considered supplemental.

Austin (2002c) applied Sevin 80S (80.07% carbaryl) to ~10% of the body surface of Sprague-Dawley rats, 8/sex/group, at doses of 0, 20, 50 or 100 mg/kg/day, 6-7 hr/day, 5 days/wk, for 4weeks. The material was applied as a powder to moistened skin and covered. Body weight,food consumption, dermal irritation and clinical signs were monitored. There were no treatment-related findings. RBC cholinesterase activity was measured pretest, before dosing on days 1, 8,15 and 22, and within 1 hr after removal of the dosing material on days 5, 12, 19 and 26. Braincholinesterase was not measured. Necropsies were not performed.

RBC cholinesterase activity was inhibited by 8-20% at 50 and 100 mg/kg when sampleswere taken within the hour after dosing (p#0.05). No consistent pattern of inhibition was notedwith samples taken before the daily dose.

The NOEL for systemic effects in this study was >100 mg/kg/day. The NOEL for RBCcholinesterase inhibition was 20 mg/kg/day based on the effects noted at 50 mg/kg/day.

This study was considered to be supplemental.

53

D. CHRONIC TOXICITY AND ONCOGENICITY

1. OverviewStudies of the toxicologic consequences of chronic carbaryl exposure in rats and mice providedevidence for oncogenicity in several tissues. Most importantly from a risk assessmentperspective, carbaryl induced vascular tumors called hemangiosarcomas (and hemangiomas) ina dose-dependent fashion in male mice, enabling the calculation of an oncogenic potency valuefor carbaryl. Less clear, but also possibly dose-dependent, was the induction of hepatocellularadenomas and carcinomas in female mice. Tumor development was also evident in malemouse kidneys and rat urinary bladder, liver and thyroid. Non-oncogenic effects, includingcholinesterase inhibition and a diverse array of adverse signs were recorded in various tissues.One clearly adverse sign, cataracts, was noted in both rats and mice at the high dose in each ofthose respective studies. While cholinesterase inhibition occurred in the 1-year dog study, nounusual clinical signs were noted.

Chronic NOELs and LOELs are summarized in Table III-9.

2. Laboratory animal studiesRats. Hamada (1993a) exposed Sprague-Dawley rats to dietary carbaryl (purity, 99%) for 2years. The doses were 0, 250, 1500 and 7500 ppm, corresponding to mean systemic doses of0, 10.0, 60.2 and 349.5 mg/kg/day in males and 0, 12.6, 78.6 and 484.6 mg/kg/day in females.There were 90 rats/sex in the control and high dose groups, and 80 rats/sex in the low and middose groups. Examined parameters included mortality, clinical signs, body weights, foodconsumption, hematology, blood chemistry, ophthalmology, gross pathology, histopathologyand organ weights. Interim sacrifices on 10/sex/dose were carried out at 26 and 52 weeks.Another 10/sex from the control and high dose groups were reestablished on basal diet for 4weeks between weeks 53 and 57. Finally, 10 rats/sex/group were subjected to clinicallaboratory exams after 78 and 104 weeks and sacrificed at study termination with the remaininganimals.

There was no effect of carbaryl on mortality. Survival rates at termination were 60%,45%*, 44%* and 61% for males and 33%, 40%, 40% and 69%* for females (*p<0.05). Thebiological significance of the increased female survival at the high dose was unclear.

The following clinical signs were likely induced by carbaryl, particularly at the high dose(but not excluding the possibility that there were lower-dose effects): hunched posture (%: 2/90,3/80, 3/80, 8/90), limited use of hind limbs (%: 0/90, 2/80, 0/80, 8/90), alopecia-front limbs (&:5/90, 8/80, 8/80, 21/90), alopecia-front feet (&: 2/90, 4/80, 9/80, 20/90), alopecia-multiple sites(&: 0/90, 0/80, 2/80, 5/90), urine stains (%: 3/90, 7/80, 2/80, 21/90; &: 3/90, 10/80, 12/80, 23/90).

Statistically significant decrements in body weight were noted at the mid and high dosesin both sexes. Such effects in mid dose males were less evident after week 18. Statisticallysignificant weight decrements were also noted in low dose males at weeks 4, 17 and 21, thoughthe infrequency of this observation cast question on its toxicologic significance. By week 105,the high dose males and females weighed 65% and 55% of controls, respectively, bothstatistically significant at the 0.05 level. Mid dose animals showed decrements of 9% in males(not significant) and 18% in females (p<0.05) at week 105.

While weekly food consumption differentials never achieved statistical significance, totalconsumption over the 2-year period was reduced by a statistically significant margin at the highdose. As the high dose body weight decrements clearly exceeded the correspondingdecrements in food consumption, the body weight effects were considered evidence of systemictoxicity. Recovery animals (dosing ceased after 52 weeks) showed greater body weights thantheir main-study counterparts by week 57, though they were still less than the unexposed

54

controls. The body weight and food consumption effects for the main study animals aresummarized in Table III-6a.

Ophthalmoscopic exams at week 104 revealed a rise in cataracts at the high dose inboth genders, though the total number of animals examined was not stated (unilateral + bilateralcataract incidence, %: 4, 6, 7, 12; &: 3, 2, 4, 10). The study ophthalmologist considered these tobe incidental. However, because of the consistent rise at the high dose in both sexes and theclear effect seen in mice (Hamada, 1993b; see below), cataracts were considered to be causedby carbaryl for the purposes of this assessment.

Several hematologic parameters were altered by statistically significant margins at thehigh dose, particularly in males. These included hemoglobin ([ wk. 57), hematocrit ([ wk. 57),mean cell volume ([ wk. 27), mean cell hemoglobin ([ wks. 27 & 53), mean cell hemoglobinconcentration ([ wks. 27 & 57 in %; \ wk. 57 in &), leukocyte count (\ wk. 27, including middose), corrected leukocyte count (\ wks. 27 & 79), lymphocytes (\ wks. 27, 53, 79) andeosinophils ([ wk. 27). These changes were not considered to carry great toxicologicsignificance, and may be secondary to other changes.

Clinical chemistry also revealed statistically significant changes at the high dose in bothsexes. These included blood urea nitrogen (&, [ wk. 79), creatinine (%, \ wk. 53, including middose), total cholesterol (% & &, [ wk. 27; %, [ wks. 53, 79, 105), aspartate aminotransferase (%& &, \ wk. 27; %, \ wk. 53), alanine aminotransferase (&, \ wks. 27, 53), total protein (%, [ wk.57), creatine kinase (%, \ wk. 53) and sodium (%, [ wk. 53). The toxicologic significance ofthese changes was unclear.

Cholinesterase measurements revealed statistically significant decrements at thefollowing times: plasma ChE in high dose males & females, wks. 26 & 52 and in high dosefemales, wks. 78 & 104; RBC ChE in mid and high dose females, wks. 52, 78 & 104 and in highdose males, wks. 52, 78 & 104; brain ChE, mid and high dose females, wks. 53 & 105, mid andhigh dose males, wk. 53 and high dose males, wk. 105. The highest level of statisticallysignificant inhibition of plasma ChE was 57% (&, wk. 78). The highest level of statisticallysignificant inhibition of RBC ChE was 38% (&, wk. 104). The highest level of statisticallysignificant inhibition of brain ChE was 31% (&, wk. 53). Inhibition of brain ChE at the mid dosereached 16% in females at week 105 and 10% in males at week 53. ChE activities appear inTable III-6b.

Urinalysis data were not provided. However, the report states that they were “generallycomparable between control and treated groups”, but with increased incidences of dark urine atthe mid and high doses, and occult blood and increased erythrocytes at the high dose. Thesechanges were described as “mild, were not accompanied by evidence of renal compromise inthe biochemical data, and cannot be definitively attributed to the administration of the testmaterial.” (p. 139)

Most of the statistically significant organ weight changes were recorded as changesrelative to brain or terminal body weights at the high dose. Statistically significant mid dosechanges were all relative. Statistically significant absolute changes occurred in week 53 femalekidney (2.56, 2.47, 2.64 and 2.22* g) and liver (12.14, 12.21, 13.71, 10.23* g), and week 105female kidney (3.34, 3.14, 3.27, 2.80* g).

Gross pathologic changes were largely restricted to high dose animals at terminalsacrifice. These included pale areas in the lung (%: 0/40, 0/31, 0/31, 4/43; &: 0/22, 0/27, 0/28,4/46), pale areas in the liver (%: 0/40, 0/31, 1/31, 4/43; &: 1/22, 0/27, 0/28, 0/46), and masses inthe urinary bladder (%: 0/40, 0/31, 0/31, 2/43; &: 0/22, 0/27, 0/28, 4/46; masses discoveredduring histologic processing, %: 0/40, 0/31, 0/31, 6/43; &: 0/22, 0/27, 0/28, 4/46).

By the terminal sacrifice, both neoplastic and non-neoplastic histopathologic changeswere evident in several organs. These are summarized in Table III-6c and discussed in the

6Exophytic growth is defined in oncology as “proliferating on the exterior or surface epitheliumof an organ or other structure, in which the growth originated” (Dorland’s Illustrated Medical Dictionary,26th Edition, 1985; W.B. Saunders Company; p. 475)

7 Lipofuscin: “any one of a class of fatty pigments formed by the solution of a pigment in fat”(Dorland’s Illustrated Medical Dictionary, 26th Edition, 1985; W.B. Saunders Company; p. 750)

55

following paragraphs.Urinary bladder: There was a pronounced increase in hyperplasia at the high dose, with

hints of an increase at the mid dose, particularly in females at terminal sacrifice. Also occurringat the high dose were increased incidences of benign transitional cell papillomas and malignanttransitional cell carcinomas, squamous metaplasia, high mitotic index and atypia. Theneoplastic and hyperplastic observations were often coincident, suggesting that the hyperplasiawas preneoplastic. The report described the transitional cell papillomas and carcinomas asexophytic 6. According to the report (p. 53), the carcinomas “exhibited many of the followingmicroscopic features: (1) nuclear and cytologic atypia, (2) hyperchromasia, (3) orientation intodense sheets, with loss of normal differentiation, (4) high mitotic index, (5) squamousmetaplasia, and (6) stalk invasion. No evidence of metastasis was present.”

Kidney: While hyperplasia of the renal transitional epithelium was a common occurrencein all of the animals, this character was also increased in high dose males. One high dose maleexhibited a transitional cell carcinoma which was judged to be due to treatment.

Liver: The incidence of hepatocellular adenomas was increased in high dose females.Hepatocytic hypertrophy, which increased at the high dose in both sexes, was described as“generally centri- to mid-lobular and was graded minimal to slight in most animals” (p. 54). Highdose females exhibited an increased incidence of pigment, which was primarily localized tohepatocytes and, to a lesser extent, to reticuloendothelial cells. The report describes thispigment as “morphologically compatible with lipofuscin 7” (p. 54). Eosinophilic foci were alsoincreased in high dose females, as were intracytoplasmic hyaline inclusions, described ashaving “a vacuolated center surrounded by an outer eosinophilic lamellar coat” (p. 55), in highdose males.

Thyroid: The incidence of follicular cell hypertrophy increased greatly in high dosefemales and slightly in high dose males. The report describes this change as “graded minimal toslight and was morphologically characterized by an increased height of follicular epithelium withan associated decreased colloid” (p. 55). An increase in benign follicular cell adenomas wasnoted in high dose males, in addition to a single high dose male exhibiting a follicular cellcarcinoma. The adenomas were described as “comprised of well-differentiated cells exhibiting afollicular growth pattern. Cystic dilatation was often present within the adenomas” (p. 55).

Lung: The incidence of focal pneumonitis and alveolar foamy macrophages, changesthat were correlated with the observation of pale foci at necropsy (see above), rose at the highdose in both sexes. As stated in the report, “alveolar foamy macrophages were most severe inthe Group 4 [high dose] females and was characterized by multifocal distribution of relativelylarge pale to eosinophilic alveolar macrophages throughout the pulmonary parenchyma. Inmany animals, this macrophage infiltrate was relatively dense and was associated with a mixedinflammatory cell interstitial infiltrate, resulting in a focal pneumonitis” (p. 56). A low incidence ofalveolar hyperplasia was also noted in high dose females.

Pancreas: High dose females showed an increased incidence of acinar cellvacuolization, described by the report as “multifocal in distribution, graded minimal in mostanimals, and was characterized by the presence of numerous oval cytoplasmic vacuoles that

56

are morphologically compatible with fat” (p. 57). A low incidence of benign acinar cell adenomasin high dose females was also observed.

Sciatic nerve and adjacent muscle: An increase in sciatic nerve degeneration wasevident at the high dose despite the observation that the lesion was common even amongcontrol animals (an indication that it evolves as a natural function of aging). According to thereport, “sciatic nerve lesions in all groups were morphologically compatible with the peripheralnerve neuropathy commonly seen in aged Sprague-Dawley rats. However, there was moreextensive microscopic evidence of myelin degeneration, macrophage infiltration, eosinophilicglobular formations, axonal loss, and fibrosis in the Group 4 [high dose] males and female rats,resulting in higher severity grades for degeneration” (p. 57). Degeneration in the adjacentskeletal muscle, likely a function of the effect on nerve, also rose at the high dose amongunscheduled death animals.

Seminal vesicle: The biological significance of the decreased seminal vesicle secretionwas not clear and may have been incidental.

The NOEL for non-oncogenic systemic effects was established at 250 ppm (10.0-12.6mg/kg/day) based on (1) the inhibition of brain cholinesterase at 1500 ppm (60.2-78.6mg/kg/day) and (2) the 18% overall inhibition in female weight gain at 1500 ppm over the 2-year period. Based on the evidence for neoplasia in the urinary bladder, liver and thyroid,carbaryl is clearly carcinogenic in rats. Tumor induction was seen mainly at the high dose,which - based on the large body weight decrements, clinical signs and statistically significantplasma, RBC and brain cholinesterase inhibition - exceeded the MTD. Hepatocellular adenomasmay also have increased in mid dose females, though in a non-statistically significant manner.The mid dose approached an MTD in this study based on body weight decrements (9% and18% in males and females, respectively, at week 105) and statistically significant RBC and braincholinesterase inhibition.

This study was considered to be acceptable by FIFRA standards.

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Table III-6a. Body weights and food consumption in Sprague-Dawley rats exposed over a 2-yrperiod to dietary carbaryl (Hamada, 1993a)

Carbaryl dose (ppm), males a Carbaryl dose (ppm), females a

Time 0 250 1500 7500 0 250 1500 7500

Body weight (g)Week 1 235 234 236 235 179 176 178 175*

Week 4 385 376* 368* 299* 244 242 236* 201*

Week 17 586 569* 569* 442* 331 327 315* 243*

Week 21 620 601* 595* 457* 344 342 326* 245*

Week 53 724 716 708 526* 431 425 410* 264*

Week 79 745 736 718 523 470 463 437 281

Week 105 717 692 677 463* 510 501 450* 278*

Food consumption (g) weeks 1-102

6568 6385 6373 5407* 4918 4938 4955 4144*

* p<0.05a Mean systemic doses: 0, 10.0, 60.2 and 349.5 mg/kg/day in males and 0, 12.6, 78.6 and 484.6mg/kg/day in females

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Table III-6b. Cholinesterase activities for Sprague-Dawley rats exposed to dietary carbaryl for 2years (Hamada, 1993a)

Carbaryl dose, males (ppm) a Carbaryl dose, females (ppm) a

Time 0 250 1500 7500 0 250 1500 7500

Week -1plasmaRBCbrain

2.8 b

5.668.1

n/a c n/a n/a 4.85.669.6

n/a n/a n/a

Week 26plasmaRBCbrain

2.25.9n/a

2.1 (5) d

5.6 (5)n/a

2.1 (5)5.3 (10)n/a

1.6* (27)4.8 (19)n/a

12.95.7n/a

12.6 (2)5.1 (11)n/a

10.7 (17)5.0 (12)n/a

6.1* (53)4.3* (25)n/a

Week 52plasmaRBCbrain (wk 53)

3.06.051.3

2.8 (7)5.7 (5)50.7 (1)

2.6 (13)4.8* (20)46.1* (10)

1.8* (40)4.6* (23)37.1* (28)

11.25.851.5

11.2 (0)5.1 (12)51.8 (+1)

9.2 (18)4.3* (26)44.8* (13)

4.9* (56)3.7* (36)35.6* (31)

Week 78plasmaRBCbrain

3.46.2n/a

3.1 (9)5.5 (11)n/a

4.0 (+29)4.8* (23)n/a

2.1 (38)3.9* (37)n/a

10.15.6n/a

9.5 (6)5.3 (5)n/a

8.2 (19)4.4* (21)n/a

4.3* (57)3.9* (30)n/a

Week 104plasmaRBCbrain (wk 105)

4.05.754.4

6.4 (+60)6.6 (+16)55.1 (+1)

3.7 (7)6.0 (5)53.1 (2)

2.3 (42)4.0* (30)49.5* (9)

7.65.857.4

7.0 (8)5.4 (7)53.5 (7)

7.2 (5)4.5* (22)48.4* (16)

4.1* (46)3.6* (38)44.8* (22)

* p<0.05a Mean systemic doses: 0, 10.0, 60.2 and 349.5 mg/kg/day in males and 0, 12.6, 78.6 and 484.6mg/kg/day in females.b Plasma and RBC ChE activities expressed as µmol/ml; brain ChE activity expressed as µmol/g.c n/a, not applicabled Numbers in parentheses represent the percentage of inhibition compared to concurrent controls.

59

Table III-6c. Neoplastic and non-neoplastic changes in Sprague-Dawley rats exposed over a 2-yr period to dietary carbaryl(Hamada, 1993a)

Carbaryl dose, males (ppm) a Carbaryl dose, females (ppm) a

0 250 1500 7500 0 250 1500 7500

Urinary bladderhyperplasia

transitional cell papilloma (B c)

transitional cell carcinoma (M c)

trans. papilloma + carcinoma f

squamous metaplasia high mitotic index atypia invasion

T b

U b

TUC g

TUC h

TUTUTUTU

3/40+++

5/30+++

0/40+++

0/30++

0/68+++

0/40+++

0/30++

0/68+++

0/67+++

0/40+++

0/30+

0/40+++

0/30++

0/40+++

0/30+++

0/40+

0/30

1/317/39

0/310/390/670/310/390/670/67

0/310/390/310/390/310/390/310/39

4/316/39

0/310/390/700/310/390/700/70

0/310/390/310/390/310/390/310/39

39/43***15/28**

10/43***2/28

12/69***9/43**

2/2811/69***22/69***

6/43*1/28

10/43***2/28

5/43*3/282/430/28

0/22+++

6/47+++

0/22++

1/47+++

1/67+++

0/22++

0/47+

0/67+++

1/67+++

0/22+

0/470/22++

0/470/22+++

1/470/220/47

0/266/43

0/260/430/690/260/430/690/69

0/260/430/260/430/260/430/260/43

3/283/41

0/280/410/680/280/410/680/68

0/280/410/280/410/280/410/280/41

42/45***14/24***

5/452/24

7/67*5/451/24

6/67*13/67***

3/450/244/450/24

13/45**1/240/450/24

Kidneyhyperplasia, transitional epith.

transitional cell carcinoma (M)

suppurative pyelonephritis pelvis pigment

TUTUTUTU

8/40+++

4/30++

0/400/300/401/300/40+

0/30+

4/313/380/310/381/310/380/310/38

6/313/390/310/390/311/390/310/39

22/43**8/281/430/280/431/282/431/28

8/2213/480/220/480/22+

2/480/220/48

18/2723/430/270/430/270/430/270/43

6/2822/420/280/420/281/420/280/42

15/466/240/460/242/460/240/460/24

60

Liverpigment

hepatocellular adenoma (B)

hepatocyte hypertrophy ic4 hyaline inclusions eosinophilic cellular alteration

TU

TUC i

TUTUTU

0/402/31

0/401/311/66

0/40+++

4/310/40+++

0/31+

5/403/31

0/313/39

1/310/391/67

1/312/390/310/395/310/39

1/314/39

2/310/393/69

1/313/390/310/394/312/39

1/433/28

1/430/281/67

30/43***5/28

12/43+++

1/287/430/28

0/22+++

6/48++

0/22+

1/48++

1/64+++

2/22+++

7/48+++

0/220/484/22+

2/48+

0/276/43

0/270/430/70

4/273/430/270/435/272/43

1/286/42

2/281/423/69

2/287/420/280/424/284/42

16/46***9/24*

4/463/24

7/68*

23/46***14/24**

0/460/24

15/464/24

Thyroidhypertrophy

follicular cell adenoma (B )

follicular cell carcinoma (M )

follic. adenoma + carcinoma l

TU

TUC j

TUC k

1/400/31+++

0/40++

0/31++

0/66+++

0/400/310/66+

0/66+++

0/311/39

2/310/392/670/310/390/672/67

0/312/39

0/310/390/690/310/390/690/69

2/436/28**

6/43*2/28

8/67**1/430/281/67

9/67**

3/22+++

1/48++

0/220/48064+

1/220/480/640/64+

3/271/43

0/270/430/700/270/430/640/70

2/280/42

0/280/420/690/280/420/690/69

30/46***3/24

1/460/241/680/460/240/681/68

Lungfocal pneumonitis alveolar foamy macrophages alveolus hyperplasia

TUTUTU

6/401/31++

11/40+++

2/31+++

1/400/31

3/310/398/313/390/310/39

4/312/399/31

10/39*0/310/39

10/434/28

26/43**12/28**

0/430/28

3/22+++

5/48+++

4/22+++

9/48+++

0/22+

0/48

4/272/433/273/430/270/43

3/280/425/289/420/280/42

35/46***7/24*

42/46***16/24***

2/460/24

61

Pancreasacinar cell adenoma (B) acinar cell vacuolization

TUTU

0/400/300/400/30

0/00/370/01/37

0/00/390/00/39

0/430/280/430/28

0/22+

0/480/22+++

0/48+++

0/250/430/250/43

0/270/420/272/42

2/460/24

15/46**5/24**

Sciatic nerve & adjacentmusclenerve degeneration e

muscle degeneration

TUTU

34/40+

10/31++

2/402/31+++

31/31*11/362/312/39

31/31*21/396/314/39

42/42*17/27*

5/438/28*

22/2219/48++

0/220/48+++

24/2515/420/260/43

26/2718/421/282/42

44/4517/23**

2/454/24*

Seminal vesicledecreased secretion

TU

1/402/31++

1/23/39

1/25/39

2/438/28*

n/a d n/a n/a n/a

*,**,***: p<0.05, 0.01, 0.001 (Fisher Exact Test) - tests performed by risk assessor.+,++,+++: p<0.05, 0.01, 0.001 (Cochran-Armitage Trend Test) - tests performed by risk assessor.a Mean systemic doses: 0, 10.0, 60.2 and 349.5 mg/kg/day in males and 0, 12.6, 78.6 and 484.6 mg/kg/day in females.b T, terminal sacrifice; U, unscheduled deathsc B, benign; M, malignantd ic, intracytoplasmic; n/a, not applicablee While incidence rates for sciatic nerve degeneration were similar among dose groups, the severity of this parameter increased at the high dose inboth sexes (see text).f Sum of "at risk" urinary bladder transitional cell papillomas and transitional cell carcinomas.g Combined "at risk" urinary bladder transitional cell papilloma incidence rate from terminal sacrifices and unscheduled deaths. The number ofanimals at risk was determined by excluding those animals that died before week 42 (which is the point when the first unscheduled death occurredwith a transitional cell papilloma). The number of males dying before week 42 was 3, 3, 0 and 2 at ascending doses, making the number of "at risk"males equal to 67, 67, 70 and 69. The number of females dying before week 42 was 2, 0, 1 and 2, making the number of "at risk" females equal to67, 69, 68 and 67.h Combined "at risk" urinary bladder transitional cell carcinoma incidence rate from terminal sacrifices and unscheduled deaths. The number ofanimals at risk was determined by excluding those animals that died before week 42 (which is the point when the first unscheduled death occurredwith a transitional cell papilloma, considered to be a benign precursor for the transitional cell carcinoma). The number of males dying before week42 was 2, 3, 0 and 2 at ascending doses, making the number of "at risk" males 68, 67, 70 and 69. The number of females dying before week 42was 2, 0, 1 and 2, making the number of "at risk" females 67, 69, 68 and 67.

62

i Combined "at risk" hepatocellular adenoma incidence rate from terminal sacrifices and unscheduled deaths. The number of animals at risk wasdetermined by excluding those animals that died before week 53 - the first unscheduled death of an animal with hepatocellular adenoma occurredin week 78. It was thus considered that any unscheduled deaths before 1 year were not likely to show hepatocellular adenoma. The number ofmales dying before week 53 was 5, 3, 1 and 4 at ascending doses, making the number of "at risk" males 66, 67, 69 and 67. The number of femalesdying before week 53 was 6, 0, 1 and 2, making the number of "at risk" females 64, 70, 69 and 68.j Combined "at risk" thyroid follicular adenoma incidence rate from terminal sacrifices and unscheduled deaths. The number of animals at risk wasdetermined by excluding those animals that died before week 53 - the first unscheduled death of an animal with a thyroid follicular adenomaoccurred in week 93. It was thus considered that any unscheduled deaths before 1 year were not likely to show thyroid follicular adenomas. Thenumber of males dying before week 53 was 5, 3, 1 and 4 at ascending doses, making the number of "at risk" males 66, 67, 69 and 67. The numberof females dying before week 53 was 6, 0, 1 and 2, making the number of "at risk" females 64, 70, 69 and 68.k Combined "at risk" thyroid follicular carcinoma incidence rate from terminal sacrifices and unscheduled deaths. The number of animals at risk wasdetermined by excluding those animals that died before week 53 - the first unscheduled death of an animal with a thyroid follicular adenoma(considered a benign precursor to thyroid follicular carcinoma) occurred in week 93. It was thus considered that any unscheduled deaths before 1year were not likely to show thyroid follicular adenomas. The number of males dying before week 53 was 5, 3, 1 and 4 at ascending doses, makingthe number of "at risk" males 66, 67, 69 and 67. The number of females dying before week 53 was 6, 0, 1 and 2, making the number of "at risk"females 64, 70, 69 and 68.l Sum of "at risk" thyroid follicular adenomas and thyroid follicular carcinomas.

63

Mice. Hamada (1993b) exposed 80 CD-1 mice/sex/dose to dietary carbaryl (purity, 99.3%) fortwo years. The doses were 0, 100, 1000 and 8000 ppm, corresponding to average systemicdoses of 0, 14.73, 145.99 and 1248.93 mg/kg/day in males and 0, 18.11, 180.86 and 1440.62mg/kg/day in females. Animals were examined for mortality, clinical signs, body weights, foodconsumption, hematology, blood chemistry, ophthalmology, gross pathology, histopathologyand organ weights. Ten mice/sex/dose were sacrificed at one year for interim gross andhistopathologic exams and for organ weight determinations.

Six high dose females died during the first 7 weeks of dosing, compared to one controlfemale and no females at either the low or mid doses, respectively. There were no furtherdifferences in mortality between controls and treated animals, including males. After week 70,animals in all groups began to die more quickly, though without an overt influence of dose. Bythe end of week 104, 54, 52, 53 and 44% of the males and 50, 50, 46 and 49% of the femalessurvived. The early high dose female deaths were accompanied during the first 3 weeks by theappearance of thinness and hunched posture in ~40% of the females in that group (and in someof the males). Interestingly, this parameter was noted only sporadically after 6 weeks, thoughthere was an increased incidence, particularly at the high dose, during the final 6 months of thestudy. Other clinical observations that occurred with higher frequency at the high dose includedlanguidity, urine staining, pale body, opaque eyes, rough haircoat, dyspnea, polypnea, and fewor no feces. The latter four signs also were increased at the mid dose, though only in males forthe latter three signs.

High dose animals exhibited a prominent body weight decrement, apparent from the firststudy week through the end of the study. Weight losses were apparent during the first twoweeks in both sexes. By the end of 4 weeks, high dose males had gained only 19% of controls,while high dose females had gained only 30% of controls. Mean body weights at week 52 were38.7, 38.5, 37.6 and 34.2* g in males (high dose males had gained 66% of controls) and 32.9,32.8, 32.7 and 29.5* g in females (high dose females had gained 77% of controls) (*p<0.05). Bytermination at week 104, mean body weights were 36.7, 37.4, 37.9 and 32.4 g in males (highdose males had gained 62% of controls) and 32.3, 33.1, 32.5, and 28.0 g in females (high dosefemales had gained 68% of controls). Small statistically significant weight differences were alsonoted at the low and mid doses, particularly in males during the first 4 weeks. However, thesewere not convincingly due to carbaryl exposure since the rate of weight gain was virtuallyequivalent to the controls. Weekly food consumption was consistently statistically reduced inhigh dose females (analyses were performed at weeks 13, 26, 50, 78 and 102 only).Consumption in mid and high dose males was notably reduced after week 73 (statisticallysignificant at week 78).

Reductions were observed in RBC counts, hemoglobin and hematocrit in high-doseanimals, with statistical significance recorded at week 53 in females and week 105 in males(these were the only two measurement times). Platelet counts were statistically increased inhigh dose females at weeks 53 (1408, 1303, 1383 and 1779* th/µl) and 105 (845, 957, 1185,1568* th/µl), as were lymphocyte, corrected white blood cell and eosinophil counts at week 53.Because of their consistency (RBC parameters) and magnitude (platelet counts in females),these changes were considered due to carbaryl exposure, though a mechanism is not known.

Statistically significant reductions in RBC cholinesterase activities were recorded in midand high dose males at week 53 (7.3, 7.0, 5.6*, 5.1* µmol/ml). Statistically significant reductionsin brain cholinesterase activities were noted for mid and high dose males and females at week53 (%: 86.0, 81.3, 70.7*, 36.9*; &: 84.1, 81.1, 73.5*, 44.6* µmol/g) and for mid and high dosemales and high dose females at week 105 (%: 59.9, 59.4, 52.0*, 35.9* µmol/g; &: 62.2, 58.7,55.2, 41.0* µmol/g). The depressed activities at the low dose were possibly carbaryl related,though the small decrement and lack of statistical significance made this unclear. In addition,

8Amyloidosis: “the accumulation of amyloid [‘an abnormal complex material, most probably aglycoprotein...’] in various body tissues, which, when advanced, engulfs and obliterates parenchynmalcells and thus injures the affected organ.” (Dorland’s Illustrated Medical Dictionary, 26th Edition, 1985;W.B. Saunders Company; p. 64)

64

clinical signs were not apparent at the low dose.With the exception of an increase in internal eye opacity in high dose female

unscheduled deaths (1/33, 1/39, 0/33, 4/40), neither unscheduled deaths nor interim sacrificesrevealed carbaryl-related pathologies. Necropsies performed on terminal sacrifice animalsrevealed the following effects, mostly at the high dose: kidney mass (%: 0/37, 0/31, 0/37, 3/30),enlarged seminal vesicle (%: 15/37, 12/31, 12/37, 1/30), uterine mass (&: 8/34, 4/31, 5/32, 0/32),uterine cyst (&: 17/34, 14/31, 20/32, 6/32), and internal eye opacity (%: 1/37, 2/31, 1/37, 4/30; &:2/34, 5/31, 2/32, 16/32).

Weight differentials were noted at wk 105 in several organ systems at the high dose.These included lung (statistically decreased absolute weight at the high dose and relativeweights at the mid and high doses in females), liver / gall bladder (statistically increased relativeweights at the high dose, both genders) and kidney (statistically increased relative weights atthe high dose, both genders). Similar changes were evident at the wk 53 interim sacrifice.Absolute and relative high dose ovary weights were statistically suppressed at interim sacrifice,though not at terminal sacrifice. These organ weight changes are summarized in Table III-7a.

Several non-neoplastic and neoplastic histopathologic changes were evident, with somenoted as early as the 1-year interim sacrifice. These are recounted by tissue in the followingparagraphs and in Tables III-7b and III-7c.

Urinary bladder: The superficial transitional epithelium (umbrella cells) exhibited anincreased incidence of eosinophilic intracytoplasmic protein-like droplets at the mid and highdoses. These were evident as early as the interim (52-wk) sacrifices. No accompanyingdegeneration, necrosis, inflammation or proliferation was noted. The toxicologic significance ofthis sign was not known.

Eye: There was an increased incidence of animals bearing bilateral cataracts at thehigh dose, though this character occurred at a relatively high frequency even among controls.The incidence of unilateral cataracts was not clearly affected.

Spleen: The incidence of splenic pigmentation rose precipitously at the high doseamong interim sacrifices of both genders. By the time of the terminal sacrifices (wk. 104) therewere no differences in incidence of this character. However, a “slight” increase in severity at themid and high doses was noted (severity data not presented in Table III-7b). Increasedextramedullary hematopoiesis was noted among high dose interim sacrifices, and exhibitedslightly increased severity at terminal sacrifice (though incidence was similar to controls). Thereport suggests that both of these parameters reflected an increased splenic turnover of redblood cells with secondary extramedullary hematopoiesis. The RBC-related hematologicchanges noted above may also be related to these splenic effects.

Duodenum, colon, testis: The incidence of amyloidosis8 increased at the high dose inthese organs among the unscheduled deaths. No association with dose was found with theterminal sacrifices, however. The toxicologic significance of this observation was not clear,though it is noted that amyloidosis was listed as a prominent cause of death in this study.

Gallbladder: The incidence of subacute inflammation of the gallbladder increasedamong terminal sacrifices at all doses. The toxicologic significance of this observation wasunclear.

Oncogenic observations are summarized in the following paragraphs. Carbaryl had clear

65

oncogenic effects, as noted below in vascular tissue (many organs), kidney and liver. Vascular tissue: An increased incidence of vascular neoplasms, identified as

hemangiomas and hemangiosarcomas, was noted in males at all doses and in females at thehigh dose. Statistical significance in pairwise comparisons was evident by the mid dose inmales. The increase occurred among unscheduled deaths and terminal sacrifices, but notamong the interim sacrifices (where the incidence was zero), suggesting that the tumorsdeveloped during the second year of the study (recognizing, of course, that the low number ofinterim sacrifices may preclude positive observations). In fact, no hemangiosarcoma orhemangioma was detected before week 72. It was thus assumed that it took at least one yearfor these lesions to develop to the point of detection. The animals that died prior to one yearwere not considered to be “at risk” and were not included in the potency calculations. The finaltotal incidence rate in males (i.e., the total number of tumor-bearing animals, understanding thatmultiple valscular neoplasms were present in some animals) was 2/66, 6/66, 10/69* and 10/68*at increasing doses (*p<0.05; see footnote #4, Table III-7c). The total number of vascularneoplasms (recognizing that more than one of such tumors was present in several animals) was2/66, 9/66*, 13/69** and 18/68*** (*,**,***; p<0.05, 0.01, 0.0001, respectively) . In females the"at risk" incidence rate was 3/63, 3/70, 4/66 and 9/61. The hemangiosarcomas / hemangiomaswere primarily localized to the liver, spleen and sternum, though other organ systems showedevidence of the tumors. Dose responsiveness through the whole dose range was apparent inthe male liver only (0/66, 4/66, 5/69* and 7/68**). As explained in the report (p. 44), “nearly all ofthe vascular neoplasms were multicentric in origin, which is typical for this tumor type in CD-1mice. The vascular system was therefore considered as a single tissue. Whether an animal hada vascular tumor in a single site or in multiple sites, it was counted as having only one vascularneoplasm... and entered under the organ vascular tissue”.

Kidney: The incidence of renal tubular neoplasms increased markedly among the highdose males (unscheduled death and terminal sacrifices). Both carcinomas and adenomas weredetected. The carcinomas were described as exhibiting “solid and trabecular / vascular patternsand were comprised of moderately differentiated renal tubular epithelium. Individual cellsexhibiting nuclear karyomegaly and atypia were present. There was no evidence of metastasis”(p. 46). The adenomas “exhibited a solid growth pattern and were comprised of well-differentiated cells with only slight nuclear atypia” (p. 46).

Liver: Hepatocellular adenomas and carcinomas were notably increased among highdose females. These lesions were “comprised of moderate to well-differentiated hepatocytesand were morphologically compatible with the typical hepatocellular tumors commonly seen inaged CD-1 mice. There was no evidence of metastasis” (p. 47). Also, a hepatoblastoma wasdetected in one high dose female, though its relation to exposure was unclear.

The NOEL for non-oncogenic effects in this study was set at the low dose of 100 ppm(14.73 mg/kg/day in males, 18.11 mg/kg/day in females), based on the presence ofintracytoplasmic droplets / pigment in the bladders of both males and females at the mid andhigh doses, and the inhibition of brain and RBC cholinesterases, also at the mid and highdoses. It is also noted that there was an increased incidence of hemangiosarcomas at all doses(including the low and mid dose in males and the high dose only in females). However, the highdose exceeded the maximum tolerated dose based on the marked decrements in body weightchanges noted throughout the study, female deaths noted in the first 7 weeks, and clinicalsigns. Even so, the appearance of hemangiosarcomas and hemangiomas in males at the otherdoses supports the conclusion that carbaryl is carcinogenic to mice. This study was consideredacceptable by FIFRA guidelines.

66

Table III-7a. Effects of carbaryl on organ weights; 2 year CD-1 mouse study (Hamada, 1993b)

Carbaryl dose, males (ppm) a Carbaryl dose, females (ppm) a

0 100 1000 8000 0 100 1000 8000

Body wts. (g) Week 53 Week 105

39.637.3

40.937.6

37.138.0

36.0*32.5*

31.732.4

35.4*34.0

35.6*32.6

32.127.6*

Brain (g) (wk. 105) 0.49 0.50 0.48 0.50 0.51 0.51 0.52 0.48

Lung (wk. 105)Absolute (g)Relative to: body wt. (%) brain wt. (ratio)

0.27

0.7140.546

0.28

0.7350.564

0.30

0.8170.608

0.25

0.7580.508

0.38

1.2000.753

0.30

0.9330.578

0.24

0.7760.465*

0.22*

0.7830.461*

Liver/gall bladder(wk 105)Absolute (g)Relative to: body wt. (%) brain wt. (ratio)

2.05

5.4344.156

2.26

5.9054.585

2.14

5.7354.436

2.51

7.522*5.059

2.05

6.2584.050

2.05

6.3324.025

1.81

5.7403.483

2.09

7.338*4.324

Kidney (wk 105)Absolute (g)Relative to: body wt. (%) brain wt. (ratio)

0.77

2.0381.562

0.77

2.0161.555

0.80

2.1431.661

0.62

2.466*1.651

0.49

1.5150.982

0.50

1.5710.991

0.54

1.7021.030

0.50

1.761*1.038

Ovary (wk 53)Absolute (g)Relative to: body wt. (%) brain wt. (ratio)

n/a n/a n/a n/a 0.042

0.13240.0818

0.034

0.09550.0633

0.049

0.13730.0918

0.028*

0.0865*0.0546*

* p<0.05a Mean systemic doses: 0, 14.73, 145.99 and 1248.93 mg/kg/day in males and 0, 18.11, 180.86 and1440.62 mg/kg/day in females

67

Table III-7b. Non-neoplastic changes in CD-1 mice exposed over a 2-yr period to dietarycarbaryl (Hamada, 1993b)

Carbaryl dose, males (ppm) a Carbaryl dose, females (ppm) a

0 100 1000 8000 0 100 1000 8000 Bladderintracytoplasmicdroplets / pigment

I b

U b

T b

0/10+++

0/33+++

0/36+++

0/100/390/31

6/10**4/31*9/37**

10/10***18/40***19/30***

0/10+++

0/34+++

0/34+++

0/100/370/30

0/106/35*4/32*

10/10***19/35***25/32***

TOTAL c 0/69+++ 0/70 13/68*** 17/70*** 0/68+++ 0/67 10/67*** 44/67***

Eyecataract, bilateral

cataract, unilateral

UT

UT

0/338/37++

3/33+

5/37

1/396/31

3/395/31

2/335/37

1/3310/37

3/4012/30

7/407/30

1/365/34 +++

5/3610/34

1/396/31

3/391/31

1/383/32

3/388/32

2/3816/32**

6/387/32

TOTAL c 16/70++ 15/70 18/70 29/70* 21/70+++ 12/70 15/70 31/70

Spleenpigmentextramedullary hematopoiesis

II

0/10+++

7/101/107/10

1/37/10

9/10***10/10+

1/10+++

7/101/107/10

2/97/10

8/10**9/10

Intestineamyloidosis(duodenum)

amyloidosis (colon)

UT

UT

7/26+

2/37

0/320/37

8/346/31

0/390/31

12/290/37

0/320/37

16/360/30

1/390/30

10/333/34

0/34++

0/34

7/384/31

0/380/31

4/322/32

0/370/32

12/371/32

3/380/32

Testisamyloidosis U

T6/33++

0/374/391/31

5/320/37

13/401/30

n/a n/a n/a n/a

Gallbladderinflammation,subacute

IUT

0/100/231/37

1/91/243/30

0/90/214/36

2/100/244/30

2/103/211/34

0/92/275/30

1/101/266/32

0/90/295/31

*,**,***: p<0.05, 0.01, 0.001 (Fisher Exact Test) - tests performed by risk assessor.+,++,+++: p<0.05, 0.01, 0.001 (Cochran-Armitage Trend Test) - tests performed by risk assessor.a Mean systemic doses: 0, 14.73, 145.99 and 1248.93 mg/kg/day in males and 0, 18.11, 180.86 and1440.62 mg/kg/day in females.b T, terminal sacrifice; U, unscheduled deaths; I, interim sacrificec Totals exclude the interim sacrifices.

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Table III-7c. Neoplastic changes in CD-1 mice exposed over a 2-yr period to dietary carbaryl(Hamada, 1993b)

Carbaryl dose, males (ppm) a Carbaryl dose, females (ppm) a

0 100 1000 8000 0 100 1000 8000

Vascular tissuehemangiosarcoma (M)hemangioma (B)hemangiosarcoma (M)hemangioma (B)hemangiosarcoma (M)hemangioma (B)

I b

U b

T b

0/100/100/330/332/370/37

0/100/103/390/392/311/31

0/100/103/330/336/371/37

0/100/103/401/404/302/30

0/100/10

1/36++

0/361/341/34

0/100/103/390/390/310/31

0/100/101/381/382/320/32

0/100/10

8/38*0/381/320/32

TOTAL c

“at risk” total (% only) d2/702/66

6/706/66

10/70*10/69*

10/70*10/68*

3/70++

3/63++3/703/70

4/704/66

9/709/61 j

Kidneytubule cell adenoma (B)tubule cell carcinoma (M)tubule cell adenoma (B)tubule cell carcinoma (M)tubule cell adenoma (B)tubule cell carcinoma (M)

I

U

T

0/100/100/320/32

0/37++

0/37+++

0/100/100/390/390/310/31

0/100/100/330/330/370/37

0/100/101/400/402/30 e

3/30

0/100/100/350/350/340/34

0/100/100/390/390/310/31

0/100/100/370/370/320/32

0/100/100/380/380/320/32

TOTAL c 0/69+++ 0/70 0/70 6/70* 0/69 0/70 0/69 0/70

Liverhepatocellular adenoma (B)hepatocellular carcinoma (M)hepatocellular adenoma (B)hepatocellular carcinoma (M)hepatocellular adenoma (B)hepatocellular carcinoma (M)

I

U

T

1/10 f

0/103/323/328/373/37

0/100/101/395/396/312/31

1/100/104/331/338/37 g

2/37

0/100/102/40 6

5/406/30 g

3/30

0/100/100/350/35

0/34+++

1/34

0/100/100/391/390/310/31

0/100/100/371/371/320/32

0/100/101/382/38

6/32 6**1/32 h

TOTAL i 17/79 14/80 15/80 16/80 1/79+++ 1/80 2/79 10/80***,**: p<0.05, 0.01 (Fisher Exact Test) - tests performed by risk assessor.+,++,+++: p<0.05, 0.01, 0.001 (Cochran-Armitage Trend Test) - tests performed by risk assessor.

a Mean systemic doses: 0, 14.73, 145.99 and 1248.93 mg/kg/day in males and 0, 18.11, 180.86 and1440.62 mg/kg/day in females.

b T, terminal sacrifice; U, unscheduled deaths; I, interim sacrificec Totals exclude the interim sacrifices.d Animals dying before 53 weeks were not considered to be at risk for harboring hemangiosarcomas orhemangiomas (the time of the first male unscheduled death in which a hemangiosarcoma / hemangiomawas detected was week 72). There were 4, 4, 1 and 2 pre-week 53 deaths among males. These valueswere subtracted from the total number of animals to produce the number of animals considered to be “atrisk”.e Includes one animal with multiple kidney tubule cell adenomas.f Includes one animal with multiple hepatocellular adenomas.g Includes two animals each at the mid and high doses with multiple hepatocellular adenomas.h This animal exhibited multiple hepatocellular carcinomas.i Because of the appearance of hepatocellular adenomas in the male interim sacrifices, all animals wereconsidered to be “at risk”.j Hemangiosarcoma + hemangioma incidence in high dose females did not reach statistical significancewith a Fisher Exact test. However, the p value was 0.056.

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In a corollary study, Debruyne (1998) attempted to determine if carbaryl-exposed tissues fromthe mouse study of Hamada (1993b) were in a state of heightened cell proliferation after oneyear of exposure. Proliferative state was assessed by the extent of immunohistochemicalstaining for proliferating cell nuclear antigen (PCNA). Based on its high proliferative state, asection of rat duodenum served as the positive control. Deparaffinized female liver and malekidney sections from the 8000 ppm mice (10/group, sacrificed after 52 weeks of exposure) werecompared with parallel sections from control animals. The tissues were reacted with PCNA,amplified with a secondary antibody, exposed to streptavidin-peroxydase and further reactedwith the chromogen aminoethylcarbazol. PCNA-positive (proliferating) cells had red-stainednuclei while non-proliferating nuclei were blue. 1000 cells were evaluated per section of liverand kidney. For male kidneys, PCNA-positive renal cortical tubular cells had a mean of1.20±1.75 per 1000 cells (range of 0 to 4), while treated tissue had 3.90±2.18 (range of 1 to 7).For female hepatocytes, the control mean was 4.60±7.68 (range of 0 to 23) and treated8.33±3.84 (range of 2 to 13). The results were interpreted as of uncertain toxicologicsignificance for male kidneys and not significant for female livers, based (1) on the range ofvariability and the small difference in males and (2) on the observation that all treated femalevalues were within the control range. Thus increased cell cycling of putative target cells was notclearly demonstrated. The positive control data from the rat were not, however, included in thereport.

This study was considered to be supplemental.^^^^^^^^^^^^^^^^^^^^

The following two studies were designed to determine if carbaryl's vascular tumorigenic effect inmice is mediated through a process involving the p53 tumor suppressor gene.

Bigot (1999) attempted to validate the p53 knockout mouse system as a rapid predictor ofrodent geno-carcinogenicity, particularly with respect to vascular tumors in mice. Male mice,strain C57B1/6 Tac-[KO]Trp53N5-T, heterozygous for the p53 tumor suppressor gene, werecompared with wild type male mice for response to urethane, a genotoxic compound known toinduce vascular tumors in lifetime studies in mice, and to d-limonene, which is not considered tobe carcinogenic in mice. 20 mice per dose group were treated with 0, 1, 10 or 100 mg/kg/day ofurethane by gavage for at least 180 days, or with d-limonene at 250 mg/kg/day. Wild type micewere given vehicle only. Body weights, food consumption and clinical signs were recorded. Atnecropsy, all major organs were examined, selected organs weighed, and tissues prepared forhistopathology.

At 100 mg/kg/day urethane, only 3 animals survived to termination. Two animals died at10 mg/kg/day. A total of 18/20 mice at 100 mg/kg/day urethane had vascular neoplasms, whichwere predominantly in the liver, at 181-184 days. At 10 mg/kg/day, 1/20 had a vascular tumor.No such tumors were observed at 1 mg/kg/day or among controls. D-limonene exposureresulted in hyperplasia of the non-glandular stomach, but was negative for tumor induction.These results supported the p53 knockout mouse as a model for identifying vascular tumorsinduced by genotoxic carcinogens.

This study is considered to be supplemental.

Chuzel (1999) used the p53 knockout mouse system, which was validated above for its rapidsensitivity to genotoxic carcinogens, particularly in the vascular system, to test whether carbarylcan act to produce such tumors within a six month period. The first male unscheduled deathshowing a hemangioma / hemangiosarcoma in the study of Hamada (1993b) was detected in

70

week 72. Consequently, the study was carried out to see if such tumors appeared in the p53knockout mouse before that time, which would suggest that carbaryl acted in a similar,presumably genotoxic, manner as urethane (Bigot, 1999).

Carbaryl (99% purity) was fed in the diet to groups of 20 male mice for at least 180 days.Mice were C57B1/6 Tac-[KO]Trp53N5-T, heterozygous for the p53 tumor suppressor gene.Doses were 0, 10, 30, 100, 300, 1000 or 4000 ppm, resulting in mean achieved doses of 0,1.76, 5.21, 17.5, 51.6, 164.5 and 716.6 mg/kg/day body weight, food consumption and clinicalsigns were recorded. Selected organs were weighed and tissues prepared for histopathologicexamination. All control and high dose animals were examined, as were all decedents. Notreatment-related deaths were reported. There were some effects on body weight and foodconsumption at 1000 and 4000 ppm. The major non-neoplastic finding was the presence of anaccumulation of "globular deposits" in the umbrella cell layer of the urinary bladder. The totalincidence was 0/20, 0/20, 0/20, 11/20, 20/20, 20/20 and 20/20 at ascending doses. Theappearance was transparent, slightly yellow and birefringent at 100, 300 and 1000 ppm, andsmaller but with a red-brown color at 4000 ppm.The severity of the accumulation increased withdose. There was no reported local irritation or hypertrophy of the bladder epithelium. Relativeorgan weights were increased in heart, liver and kidney at 4000 ppm and for kidney at 1000ppm as well.

The NOEL was set at 30 ppm (5.2 mg/kg/day) based on the histopathologicobservations ("globular deposits" in the umbrella cell layer of the urinary bladder) at 100 ppm.There was no treatment-related evidence of neoplasia or preneoplasia in vascular tissue or anyorgans examined. Several spontaneous neoplasms were found, though none were present at4000 ppm. The negative result in this study lowered the possibility that carbaryl-inducedneoplasms in male CD-1 mice, including hemangioma / hemangiosarcoma, resulted fromprocesses mediated by the p53 tumor suppressor gene in a manner similar to urethane.However, genotoxicity could not be totally excluded as a mode of action for carbaryl.

This study was considered to be supplemental.^^^^^^^^^^^^^^^^^^^^

The following two open literature studies examine the question of whether carbaryl canmodulate tumor production in mice in the context of stimulation by other carcinogens. The first,by Triolo et al. (1982), shows an increase in the number of lung tumors when two gavagetreatments with benzo[a]pyrene were accompanied by 20 weeks of exposure to dietary carbaryl.The second, by Shukla et al. (1992), shows that carbaryl has skin tumor initiating capability in astandard initiation-promotion protocol using phorbol ester as the promoter. Taken together, thestudies emphasize that data from standard rodent oncogenicity studies do not provide acomplete picture of carbaryl's oncogenic effects.

Triolo et al. (1982) studied the effects of dietary carbaryl on benzo[a]pyrene (BP)-induced lungtumor production (dietary toxaphene was also examined, but will not be discussed here).Female A/J mice, 11-31 animals per treatment, received feed containing 0 (5% corn oil) or 1000ppm carbaryl for 20 weeks, with the choice of dose based on preliminary data indicating noeffect on body weight gain. Three mg BP was administered by intubation on study days 7 and21. After the 20-wk period, the animals were sacrificed for tumor enumeration (only tumorsgreater than 1 mm were counted). Similarly treated mice were analyzed for liver and lung BPhydrolase (BPH), an enzyme involved in the metabolism of BP.

Carbaryl had neither a convincing nor a consistent effect on lung tumor incidence in theabsence of BP. For example, the insecticide was associated with an increase in the percentageof mice with tumors in one experiment (9% to 31%, not statistically significant, Expt. #1) and a

71

decrease in another experiment (23% to 10%, Expt. #2). The number of tumors per mouseincreased slightly in both experiments, though in non-statistically significant manner (Expt. #1from 1.0±0.0 to 1.2±2.2; Expt. #2 from 1.1±0.0 to 1.3±0.3). However, in the only experimentconducted in the presence of BP, carbaryl increased the percentage of mice with tumors from88% to 100% (not statistically significant) and the number of tumors per mouse from 3.7±0.6 to5.7±1.4 (p<0.05). Assay of BPH activity in non-BP-treated animals showed no statisticallysignificant effects in liver or lung. In the presence of BP, a statistically significant increase inBPH activity, from 3.06±0.14 pm/mg protein to 3.86±0.11 pm/mg protein (p<0.025), was notedin the lung, but not in the liver. The authors speculated that the increased lung enzyme activitymay be mechanistically related to the increased tumor production in the same organ, thoughthis will require further experimental verification.

Shukla et al. (1992) examined the ability of carbaryl to act as a complete carcinogen, initiatorand / or promoter following dermal exposure in female Swiss albino mice (20 per dose group).Each experiment ran for ~52 weeks (promotion treatment continued for 51 weeks afterinitiation).

Expt. #1 (complete carcinogenesis): Group I - untreated controls; Group II - 5 µgbenzo[a]pyrene (BP), 3x/wk; Group III - 100 mg/kg carbaryl, 3x/wk; Group IV - vehicle control,100 µl acetone, 3x/wk. Result: tumors were identified only in Group II (100% of survivorsformed skin tumors by the end of the study).

Expt. #2 (initiation): Group I - untreated controls; Group II - single treatment with 100mg/kg carbaryl, followed 1 week later by 5 µg 12-O-tetradecanoyl phorbol-13-acetate (TPA),3x/wk; Group III - multiple treatments (3x/wk for 3 weeks) with 100 mg/kg carbaryl, followed 1week later by 5 µg TPA, 3x/wk; Group IV - single treatment with 52 µg DMBA, followed 1 weeklater by 5 µg TPA, 3x/wk; Group V - multiple treatments (3x/wk for 3 weeks) with 100 mg/kgcarbaryl, followed 1 week later by 100 µl acetone, 3x/wk; Group VI - multiple treatments(3x/wkfor 3 weeks) with 100 µl acetone, followed 1 week later by 5 µg TPA, 3x/wk. Result: 2/17survivors from Group II (single carbaryl treatment initiation protocol), 8/13 survivors from GroupIII (multiple carbaryl treatment initiation protocol), and 16/16 survivors from Group IV (singleDMBA treatment initiation protocol) showed skin tumors; no other group showed tumors.

Expt. #3 (promotion): Group I - untreated controls; Group II - single treatment with 52 µgDMBA, followed 1 week later by 100 mg/kg carbaryl, 3x/wk; Group III - single treatment with 52µg DMBA, followed 1 week later by 5 µg TPA, 3x/wk; Group IV - single treatment with 100 µlacetone, followed 1 week later by 100 mg/kg carbaryl, 3x/wk; Group V - single treatment with 52µg DMBA, followed 1 week later by 100 µl acetone, 3x/wk. Result: only Group III (DMBAinitiation, TPA promotion) resulted in tumors (16/16 survivors).

These results indicate that while carbaryl was negative for complete carcinogenesis andfor promotion, it does indeed act as an initiator in the mouse 2-stage skin carcinogenesisprotocol. All tumors were considered benign in nature (pedunculated and flat squamous cellpapillomas, flat squamous cell papillomas, keratoacanthomas and mixed type tumors).

^^^^^^^^^^^^^^^^^^^^

Dogs. Hamada (1987) exposed 6 beagles/sex/dose group to carbaryl (purity, 99%) in the dietfor one year. The doses were 0, 125, 400 and 1250 ppm, corresponding to average systemicdoses of 0, 3.4, 11.2 and 33.8 mg/kg/day in males and 0, 3.7, 11.0 and 34.4 mg/kg/day infemales. Twice daily observations were made for mortality / moribundity, once daily for clinicalsigns. Body weight and food consumption were determined weekly, plasma and RBCcholinesterase activities three times prior to treatment (weeks -3, -2 and -1) and during weeks 5,13, 26 and 52. Brain cholinesterase activity was determined at study termination. Additional

72

laboratory studies measured conventional hematologic, clinical chemical and urinalysisparameters at weeks -2, 13, 26 and 52. Ophthalmologic exams were conducted before theinitiation of treatment and at termination. Necropsies, organ weight determinations andhistopathology were also executed at termination.

There were neither deaths nor clinical signs attributable to carbaryl during the study.Nonetheless, high dose females gained less weight than controls throughout. This decrementachieved statistical significance between weeks 0-5 only (female weight gain, ascending doses,weeks 0-5: 1.0, 1.1, 1.0, 0.5* kg; *p<0.05), consistent with slightly lowered food consumption foreach period (not statistically significant). There were statistically significant increases in whiteblood cell counts among high dose males at week 26 (10.3, 10.7, 10.4, 13.4* Th/µl) and 52(10.3, 11.1, 9.9, 15.2* Th/µl), and in segmented neutrophil counts at week 52 (7.0, 8.2, 7.5,11.4* Th/µl). High dose females showed statistical decrements in albumin levels at allmeasurement intervals (eg., at week 52: 3.5, 3.5, 3.4, 3.2* g/dl).

Cholinesterase activities were suppressed at all time points, often by statisticallysignificant margins (Table III-8). For brain cholinesterase, the level of inhibition reached 36% atthe high dose, though even at the low dose a statistically significant 20% level of inhibition wasnoted in females. RBC cholinesterase inhibition as high as 56% was noted at the high dose(week 5), with non-statistically significant inhibition as high as 14% (week 13) noted at the lowdose. Plasma cholinesterase inhibition reached 66% (week 5) at the high dose, with statisticallysignificant inhibition as high as 23% (week 13) noted at the low dose.

Gross necropsies were unremarkable. Organ weight determinations revealed asignificant increase in absolute liver weight in high dose males (242, 255, 269, 301* g; *p<0.05),though a corresponding effect was not evident in females. A statistically significant decrement inthyroid weight relative to body weight was also noted in males (0.011, 0.009, 0.010, 0.008*), butwas not accorded biological significance. Histopathology did not reveal lesions that were clearlydependent on carbaryl exposure.

The LOEL was set at 125 ppm (3.4-3.7 mg/kg/day), based on cholinesterase inhibition(brain, RBC and plasma). Because this was the low dose, a corresponding NOEL was not set.This study was deemed acceptable by FIFRA standards.

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Table III-8. Suppression of cholinesterase activities in beagle dogs by dietary carbaryl; 1-yrstudy (Hamada, 1987)

Carbaryl dose (ppm), males a Carbaryl dose (ppm), females a

Time 0 125 400 1250 0 125 400 1250

Plasma ChE, µmol/ml

Week -1 8.5±2.02 8.5±1.02 8.1±1.58 7.8±1.50 8.8±1.04 7.4±1.02 8.9±0.96 9.0±1.40

Week 5 8.5±1.83 7.3±1.0486% b

5.4±1.12*64%

2.9±0.84*34%

8.1±1.47 6.3±0.73*78%

5.6±0.82*69%

3.2±0.81*40%

Week 13 8.6±1.94 7.5±1.1687%

5.7±1.07*66%

3.7±0.99*43%

8.6±0.91 6.6±0.77*77%

6.2±1.15*72%

3.7±0.71*43%

Week 26 8.6±1.98 7.4±1.0586%

5.6±1.02*65%

3.5±1.00*41%

8.9±1.02 7.2±1.48*81%

6.6±1.04*74%

4.0±0.92*45%

Week 52 8.1±2.49 7.8±1.3196%

5.7±1.21*70%

3.4±1.14*42%

7.7±1.24 6.8±1.2088%

7.0±1.71 91%

4.1±1.08*53%

RBC ChE, µmol/ml

Week -1 7.6±1.66 7.4±1.45 7.5±1.59 5.6±0.81 9.4±2.17 9.3±1.23 8.9±1.03 10.0±0.94

Week 5 7.3±1.42 6.5±1.2389%

5.6±0.90*77%

3.20±0.73*44%

10.5±1.99 9.1±1.55 87%

6.9±0.76*66%

6.5±0.79*62%

Week 13 7.2±1.43 6.2±1.4686%

5.2±0.61*72%

3.7±0.84*51%

8.6±1.85 8.3±1.66 97%

6.1±0.68*71%

6.1±0.76*71%

Week 26 8.0±1.21 7.5±1.1894%

6.5±0.94 81%

4.3±0.87*54%

10.4±1.66 9.5±1.2491%

7.4±0.95*71%

6.6±0.99*63%

Week 52 8.5±1.77 7.9±1.50 93%

6.8±0.89 80%

4.0±0.55*47%

10.0±2.03 9.3±1.26 93%

8.2±1.0982%

7.0±0.64*70%

Brain ChE, µmol/g

Week 52 11.3±3.41 9.7±2.90 86%

7.7±2.07 68%

8.5±1.38 75%

9.0±1.23 7.2±0.64*80%

7.0±1.19*78%

5.8±0.48*64%

*p<0.05a Equivalent to average systemic doses of 0, 3.4, 11.2 and 33.8 mg/kg/day in males and 0, 3.7, 11.0 and34.4 mg/kg/day in females. b Percent of concurrent control activities.

74

Table III-9. NOEL and LOEL values for subchronic and chronic toxicity studies on carbaryl

Species,strain

Study type &exposure regimen Effects at LOEL NOEL LOEL Reference f

Subchronic studies:

Dog, Beagle 5-wk dietary none 125 ppma (M: 3.83mg/kg/day; F: 4.11mg/kg/day)

>125 ppm1 (M:3.83 mg/kg/day; F:4.11 mg/kg/day)

SupplementalHamada(1991)

Mouse,TSG p53wild type

4-wk dietary, malesonly

[relative liver wt. b 1000 ppm (222mg/kg/day)

2000 ppm (424mg/kg/day)

SupplementalDange(1998)

Rat, Wistar 50-day dietary,males only

\ maze function, \ brain ChEactivity, altered EEG patterns

<10 mg/kg/day 10 mg/kg/day SupplementalDesi et al.(1974)

Rat,Sprague-Dawley

4-wk dermal c systemic: no systemic toxicitylocal: atoniaChE: inhibition of brain & RBCChE

systemic: 100mg/kg/daya local: 50mg/kg/dayChE: 20 mg/kg/day

systemic: >100mg/kg/daya local: 100mg/kg/dayChE: 50 mg/kg/day

SupplementalAustin(2002a)

Chronic studies:

Dog, Beagle 1-yr dietary e \ brain, RBC and plasma ChEactivity

<125 ppm (3.4-4.7mg/kg/day)

125 ppm (3.4-4.7mg/kg/day)

AcceptableHamada(1987)

Mouse, CD-1

2-yr dietary bladder histopathologic effects,inhibition of brain & RBC ChE d

100 ppm (~14.73mg/kg/day)

1000 ppm (~145.99mg/kg/day)

AcceptableHamada(1993b)

p53 Mouse,CD-1(C57B1/6Tac-[KO]Trp53N5-T)

6-month dietary globular deposits in the umbrellacell layer of the urinary bladder

30 ppm (~5.2mg/kg/day)

100 ppm (17.5ppm)

SupplementalChuzel(1999)

Rat,Sprague-Dawley

2-yr dietary \ wt. gain and \ brain ChE activity 250 ppm (10.0-12.6mg/kg/day)

1500 ppm (60.2-78.6 mg/kg/day)

AcceptableHamada(1993a);

a Highest dose tested.b This LOEL determinant was considered conditional - there was no histopathology done to determine ifthe increased relative liver weight was adverse in nature.c Dermal exposure was for 5 days/wk, 6 hr/day.d There was also an increase in hemangiosarcomas at all doses in the Hamada (1993b) mouse study.e The 1-yr dog dietary study represents the critical chronic study. Benchmark dose calculations indicate anLED10 of 0.5 mg/kg/day.f The designation "Acceptable" indicates that the study was successfully completed according to FIFRAguidelines. "Supplemental" indicates that the study was not conducted according to FIFRA guidelines;however, such studies were reviewed and considered to contribute to the general genotoxic picture of thechemical.

75

E. GENOTOXICITY

1. OverviewCarbaryl failed to produce gene mutations in four of the five in vitro studies reviewed, includingtwo FIFRA-compliant studies and two supplemental studies. Carbaryl did produce mutations toouabain resistance in one supplemental study in V79 Chinese hamster fibroblasts. Carbarylalso caused chromosomal aberrations in four of six studies, including one FIFRA-compliantstudy. Of those four positive studies, only one was in vivo, and that was in Allium cepa (oniontree), which was of questionable relevance to mammalian systems. Both of the negativechromosomal aberration studies (one FIFRA-compliant, one supplemental) were performed invivo. Two of the four reviewed DNA damage studies were positive. Both of these studies weresupplemental and both were performed in vitro. The two negative studies, one in vivo and onein vitro, were FIFRA-compliant.

One reviewed study demonstrated that nitrosocarbaryl could be produced from carbaryland nitrite under acidic in vitro conditions. A separate study showed that nitrosocarbaryl causedchromosomal aberrations in Chinese hamster fibroblasts. Finally, one study in V79 Chinesehamster fibroblasts showed that, like carbaryl, the carbaryl metabolite %-naphthol was toxic andinduced c-mitosis, an aberrant form of mitosis that may reflect effects on mitotic spindleformation.

The results of the genotoxicity tests are summarized in Table III-10.

2. Gene mutationLawlor (1989) studied the potential mutagenicity of carbaryl (99.3% purity) in the AmesSalmonella reverse mutation assay. The tester strains were TA1535, TA1537, TA1538, TA98and TA100. Two trials were conducted, with and without Aroclor 1254-induced male Sprague-Dawley rat liver microsomes, using triplicate platings at a range of doses. A preliminary testindicated cytotoxicity at and above 667 µg/plate. Use of positive control substances indicatedthe appropriate sensitivity of the tester strains. Trial 1: 0 (DMSO), 5, 10, 50, 100, 500, 1000µg/plate; Trial 2: 0 (DMSO), 10, 50, 100, 500, 1000, 2000 µg/plate. There was no evidence foran increased reversion rate at any carbaryl concentration. Carbaryl was not considered to bemutagenic in this assay.

The study was considered acceptable according to FIFRA guidelines.^^^^^^^^^^^^^^^^^^^^

Young (1989) studied the potential mutagenicity of carbaryl (99.3% purity) in the Chinesehamster ovary cell / HGPRT forward mutation assay both with and without an Aroclor 1254-induced rat liver microsomal activation system. There were two trials, each using a singleculture per concentration. Without activation, trial 1: 0 (DMSO), 0.001, 0.01, 0.03, 0.05, 0.08,0.1, 0.15, 0.2, 0.3 (toxic) mg/ml; trial 2: 0 (DMSO), 0.01, 0.05, 0.1, 0.15, 0.2, 0.25 (toxic), 0.3(toxic) mg/ml. With activation, trial 1: 0 (DMSO), 0.001, 0.01, 0.03, 0.05, 0.08, 0.1, 0.15, 0.2, 0.3(toxic) mg/ml; in trial 2, only one concentration could be scored due to cytotoxicity with a new lotof S9 microsomes; trial 3: 0 (DMSO), 0.001, 0.005, 0.01, 0.02, 0.04, 0.06, 0.08, 0.1 (toxic), 0.13(toxic) mg/ml. There was no reproducible increase in forward mutations. Carbaryl was notconsidered to be mutagenic in this assay.

This study was considered acceptable according to FIFRA guidelines.^^^^^^^^^^^^^^^^^^^^

Ahmed et al. (1977a) studied the ability of carbaryl and three other pesticides (chlordane,dieldrin and 2,4-D-fluid) to induce ouabain-resitant mutants in V79 Chinese hamster cells. Cell

76

survival in the presence of 1 µM ouabain was determined using a concentration range of 0.1 -1000 µM. For the mutation assay, thirty 9-cm plates were seeded with 105 cells/plate, followed 4hours later by the addition of 10 µM pesticide (calculated to generate survival of 40-75%). After48 hours, 1 mM ouabain was added. Resistant colonies were enumerated 1 week later.

Under these conditions, carbaryl, chlordane, dieldrin and 2,4-D-fluid induced mutationfrequencies (per 104 survivors) of 15.3, 26.9, 16.4 and 25.5, respectively (control frequency:1.8). Percent survival was 66, 44.4, 77.8 and 41.3 (controls: 93). Subculture of resistantcolonies in the presence of ouabain showed that resistance was maintained, thus indicating thatthe change was heritable.

This study was considered to be supplemental. 3. Chromosomal aberrationsWeil (1972) studied the potential for carbaryl-induced dominant lethal mutations in rats (strainnot identified) as part of a 3-generation reproductive toxicity, teratology and mutagenicity study.Animals were dosed 5 days/week with carbaryl (99.6% purity) in feed at 0, 7, 25,100 or 200mg/kg/day, by gavage in corn oil at 0, 3, 7, 25 or 100 mg/kg/day, or in feed containing corn oil at0 or 100 mg/kg/day. The F2a males were withdrawn at 7 months old and mated weekly withunexposed females for 10 weeks. The feeding study (pure and with corn oil) evidenced nodose-related or consistent differences from controls, resulting in a NOEL of 200 mg/kg/day. Thegavage study resulted in a significant reduction in mean implants or viable fetuses at 100mg/kg/day for the week 8 matings only: 12.5 vs. 14.0 (controls) and 11.5 vs. 14.0 (controls),respectively. As this was not regarded as meaningful, the gavage NOEL was set at 100mg/kg/day.

This study was deemed supplemental.^^^^^^^^^^^^^^^^^^^^

Murli (1989) studied the potential for carbaryl-induced chromosomal aberrations in vitro usingChinese hamster ovary (CHO)-WBL cells. Duplicate cultures were exposed to carbaryl (99.3%purity), without activation, to 0 (negative and solvent), 7.5, 10, 25, 50 or 75 µg/ml for 17.5 hoursincubation, with harvest at 20 hours. Further duplicates were exposed, with S9 microsomalactivation, to 0 (negative and solvent), 150, 200, 250 or 300 µg/ml for 2 hr with harvest at 20and 30 hours. In both cases, the positive controls were functional. The harvest times werebased on a preliminary study with BrdUrd staining for determination of cell cycles. Cytotoxicitywas evident at around 25 µg/ml in the absence and 200 µg/ml in the presence of S9microsomes. No increase in aberrations was detected in the absence of an S9 activationsystem. However, in the presence of S9, an increase in aberrations/cell, percent cells withaberrations and percent cells with >1 aberration at both harvest times was detected at all doses.Dose responsiveness was not evident. Thus the lowest effective level of carbaryl was notdetermined. The types of aberrations seen included chromatid and chromosome gaps,chromatid and chromosome breaks, interstitial deletions, triradials, quadriradials, complexrearrangements and dicentrics. Carbaryl is considered to be active in this assay in the presenceof an S9 activating system.

This study was considered acceptable by FIFRA guidelines.^^^^^^^^^^^^^^^^^^^^

Marshall (1996) studied the potential for carbaryl to induce micronuclei in vivo in the bonemarrow erythrocytes of treated CD-1 mice. Animals were dosed with carbaryl (99.9% purity) in0.5% carboxymethylcellulose at doses of 0, 50, 100 or 200 mg/kg/day for two consecutive days.Five animals/sex/dose were sacrificed after a further 24 or 48 hours. Cyclophosphamide was

77

used as the positive control and was functional. At 200 mg/kg the animals showed lethargy,which lasted ~2 hours after the first dose, with eye closure in 3 females and eye secretions inone. Body weight loss was detected in 2 males and 10 females at the high dose. For eachanimal, 2000 polychromatic erythrocytes were scored for micronuclei and the PCE/NCE ratiowas reported. Carbaryl did not induce micronuclei in this study.

This study was considered acceptable by FIFRA guidelines.^^^^^^^^^^^^^^^^^^^^

Ishidate and Odashima (1977) screened 134 compounds (including carbaryl andnitrosocarbaryl) for their ability to produce chromosomal aberrations in vitro in a clonal sublineof a Chinese hamster fibroblast line. Each chemical was tested at three doses, including the50% growth inhibition dose. Following 6-48 hr of exposure, the cells were treated with colcemid,trypsinized, incubated in hypotonic KCl solution, fixed, a few drops of suspension applied to aclean slide, which was then dried and stained. One hundred well-spread metaphases wereexamined for chromatid gaps, chromatid breaks, chromatid or chromosomal translocations, ringformation, fragmentation / pulverization and polyploidy.

Sixty three of 134 compounds were negative (defined as less than 4.9% cells withaberrations), 17 / 134 were suspicious (5.0% - 9.9% with aberrations) and 54 / 134 werepositive (> 10% positive cells). Carbaryl (referred to as naphthyl-N-methylcarbamate) generated35.0% aberrations after 48 hours at a maximum effective dose of 0.03 mg/ml (1.5x10-4 M). Thetypes of aberrations included chromatid gaps (predominant), chromatid / chromosomal breaks(predominant), translocations (predominant), ring formation and fragmentation. Nitrosocarbaryl(referred to as naphthyl-N-nitroso-N-methylcarbamate) generated 81.0% aberrations after 24hours at a maximum effective dose of 0.015 mg/kg (0.7x10-4 M). The types of aberrationsincluded chromatid gaps, chromatid / chromosomal breaks (predominant), translocations(predominant) and ring formation.

This study was considered to be supplemental. ^^^^^^^^^^^^^^^^^^^^

Soderpalm-Berndes and Onfelt (1988) studied the effects of carbaryl and %-naphthol on mitosisin V79 Chinese hamster fibroblasts. Of particular interest was the possible role of antioxidants(selenite and %-tocopherol) in modulating the toxic response. Parameters followed included (1)survival (measured as post treatment colonizing percentage following trypsinization); (2) c-mitosis (not precisely defined in the report, though presumably an aberrant mitotic form;measured after fixation of cells grown directly on microscope slides) and monopolar mitoticconfigurations (basically indicators of the location of the metaphase chromosomes in mitoticcells); (3) TCA-soluble sulfhydryls (i.e., non-protein sulfhydryls - NPSH - considered torepresent mostly reduced glutathione) and protein sulfhydryls (PSH - presumably an indicationof the extent of macromolecular crosslinking); (4) various enzyme activities (glutathione-S-transferase, selenium-dependent glutathione peroxidase and glutathione disulfide reductase); (5) ATP measurements; and (6) lipid peroxidation (using the "thiobarbituric acid test").

(1) In the absence of antioxidants, carbaryl and %-naphthol were toxic (i.e., inhibitedcolony formation upon subculture) in the 200-400 µM range. Addition of %-tocopherolameliorated this response somewhat.

(2) Induction of c-mitosis in the absence of antioxidants passed the 10% point between50 and 100 µM carbaryl, reaching 60-70% at 400 µM. In the presence of antioxidants the 10%point occurred between 100 and 200 µM, with c-mitosis reaching 37-42% at 400 µM carbaryl. %-naphthol was less efficient in inducing c-mitosis. In addition, the number of metaphase cells witha normal-shaped morphology and centrally located chromosomes decreased from nearly 100%

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to less than 50% in the presence of 400 µM carbaryl, having been replaced by elongated cellswith chromosomes located at one pole. The antioxidants appeared to have little effect on thisprocess.

(3) Carbaryl treatment between 25 and 400 µM resulted in a dose-dependent decreasein NPSH (100% in controls, 88% at 25 µM, 32% at 400 µM) and, to a lesser extent, PSH (97%at 25 µM, 79% at 400 µM). Neither %-tocopherol nor selenite affected NPSH levels, thoughthere may have been a %-tocopherol-based protective effect on PSH levels at 200 and 400 µMcarbaryl. %-Naphthol had no effect on NPSH or PSH levels.

(4) %-Tocopherol treatment increased glutathione-S-transferase activity by 39% in theabsence of carbaryl and by 13% in the presence of 400 µM carbaryl. Selenite increasedselenium-dependent glutathione peroxidase activity by 50% in the absence of carbaryl and by12% in the presence of 400 µM carbaryl.

(5) In the absence of glucose, both carbaryl and %-naphthol reduced the amount ofcellular ATP, particularly at 200 and 400 µM. The investigators suspect that %-naphthol(produced from carbaryl metabolism) may be an uncoupler of oxidative phosphorylation.

(6) Lipid peroxidation was increased in a dose-dependent manner between 25 (~110%of controls) and 400 µM (~170% of controls) carbaryl. Selenite and %-tocopherol both greatlyreduced the peroxidation.

The investigators concluded from these data that carbaryl affects mitotic spindleformation, possibly through a decrease (reversible and irreversible) in cellular levels ofglutathione S-transferase activity or through an increase in lipid peroxidation (which may itselfbe a manifestation of lowered glutathione S-transferase activity). They discounted a role forglutathione S-transferase or lipid peroxidation in the formation of monopolar metaphaseconfigurations.

This study was considered to be supplemental.^^^^^^^^^^^^^^^^^^^^

Grover et al. (1989) examined the ability of carbaryl to induce mutations in the Salmonellahistidine reversion assay and chormosomal aberrations in root meristems of Allium cepa.

Carbaryl was negative in the Salmonella assay (three strains tested: TA98, TA102 andTA1535) both in the absence and presence of S9 and S14 microsomes (the latter were derivedfrom wheat seedlings). Doses tested were 0, 1, 5, 10, 50, 100, 500, 1000, 5000 and 10,000µg/plate. Depending on the strain and the presence/absence of activating microsomes, toxicitybecame evident between 1000 and 5000 µg/plate.

Incubation of A. cepa root tips in solutions containing 0, 0.1, 0.4, 0.7, 1.0 or 1.3%carbaryl depressed the mitotic rate and induced mitotic and chromosomal abnormalities in theexposed cells both in the presence and absence of S14 microsomes, essentially at all doses.While the relevance of the root tip assay to mammalian cells in vitro or in vivo is not known,these results are consistent with other studies on carbaryl which indicate that it disturbs mitosisand chromosomal integrity.

This study was considered to be supplemental.

4. DNA damageCifone (1989) studied the potential for carbaryl to induce unscheduled DNA synthesis in vitro inprimary hepatocytes isolated from adult male Fischer 344 rats. Cultures were exposed tocarbaryl (99.3% purity) at 0 (DMSO), 0.5, 1, 2.5, 5, 10 or 25 µg/ml (trial 1), or 0 (DMSO), 5, 7.5,10, 15, 20 or 25 µg/ml (trial 2). Higher concentrations were also tested, though the level oftoxicity seen at those concentrations was inconsistent with a valid test. 150 cells perconcentration from triplicate coverslips were scored. A small increase in labeled nuclei was

79

noted at 10 µg/ml in trial 1 (average % nuclei with $6 grains = 20.4, vs. 4.7 in solvent controls,3.3-6.7% in the remaining doses [including 25 µg/ml], and 99.3% in the presence of 2-acetylaminofluorene [2-AAF]). However, the lack of a dose response, the non-reproducibility intrial 2, and the absence of an increase in net nuclear grains at any dose, make it unlikely thatcarbaryl was active in this assay. In conclusion, these data were not supportive of an inductiverole for carbaryl in unscheduled DNA synthesis in this study.

This study was considered acceptable by FIFRA guidelines.^^^^^^^^^^^^^^^^^^^^

Sagelsdorff (1994) studied the potential for hepatic protein- and DNA- binding by carbaryl inmale CD-1 mice. Covalent binding of [1-14C-naphthyl]--carbaryl to chromatin protein and to DNAwas determined using 5 groups of 4 - 6 animals per group. Group 1: one dose of 75 mg/kglabeled carbaryl by gavage; Group 2: fed 8000 ppm carbaryl for 13 days prior to a single doseas for Group 1; Group 3: untreated (used for controls of the extraction procedures); Group 4: fed8000 ppm carbaryl for 14 days; Group 5: untreated. Groups 4 and 5 were not processed.Urinary excretion was measured for a single animal from Groups 1 and 2 over 24 hours andfound to be 33% and 31%, respectively, of the administered dose. Fecal excretion was notmeasured. Livers from 2 animals of the same group were pooled for processing - they werehomogenized, chromatin precipitated, deproteinated and DNA further pruified onhydroxyapatite, dialyzed and precipitated with ethanol. Chromatin protein was precipitated withacetone and dissolved in 1% SDS several times. Radioactivity was determined by liquidscintillation counting. Binding was determined as a function of mg protein and mg DNA. Thepmol/mg binding to protein ranged from 7 to 11, with no difference between groups 1 and 2. ForDNA, binding (dpm/mg) was <5.99 with an 80% counting efficiency and a limit of detection of2.7 cpm over background. The Covalent Binding Index (CBI) was calculated to be <0.1 as amaximum DNA-binding ability. This result gives no indication for a genotoxic potential forcarbaryl mediated by DNA binding. The CBIs for strong hepatocarcinogens (eg., aflatoxin B1)are orders of magnitude higher.

This study was deemed acceptable by FIFRA standards.^^^^^^^^^^^^^^^^^^^^

Ahmed et al. (1977b) studied the ability of carbaryl and 12 other pesticides to induceunscheduled DNA synthesis (UDS) in SV-40 transformed human cells (VA-4) in vitro, both in thepresence and absence of an S9 microsomal activating system. VA-4 cells can be propagatedindefinitely in culture and exhibit similar DNA repair characteristics to the human primaryfibroblast cultures, Detroit-500 and WI-38. Cells were seeded onto 11.22 mm coverslips in 100-mm dishes at 104/cm2. Twenty four hours later hydroxyurea was added to inhibitsemiconservative DNA synthesis. 3H-thymidine, hydroxyurea and the test article (±S9) wereadded after 5 further hours. Coverslips were removed at intervals of 1, 3, 5, 8 and 12 hours,fixed, hydrated, mounted onslides, dipped in photo emulsion, kept under dark conditions for 4days, developed, fixed and stained. The number of grains per nucleus were counted. Vehicle(acetone) and non-vehicle controls were run. In a second technique, the effect of carbaryl onphotolysis-induced DNA fragmentation at 313 nm was measured using alkaline sucrosegradients..

Carbaryl, at concentrations of 1 - 1000 µM, activated UDS both in the absence andpresence of S9 microsomes. This was evident at the p<0.05 level of significance. For example,after 8 hr, 100 µM carbaryl produced 17.4±2.0 grains / nucleus compared to 2.0±0.7 grains /nucleus in controls. The BUdR experiment produced 0.5, 0.6 and 1.5 breaks/108 daltons atcarbaryl concentrations of 1, 10 and 100 µM carbaryl, respectively.

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This study was considered to be supplemental.^^^^^^^^^^^^^^^^^^^^

Onfelt and Klasterska (1984) examined sister chromatid exchanges (SCE) and mutations tothioguanine resistance (TGR) in V79 Chinese hamster cells after treatment with carbaryl.Exponentially growing cells were exposed to 50 or 100 µM carbaryl dissolved in acetone (final[acetone] = 0.25%) for 3 hours. Cultures destined for cytologic examination (SCE) were thentreated with BrdUrd at 37°C for 24 hr in the dark, with colcemid added 2 hours before harvest.They were then processed for chromosome visualization. Cultures destined for TGR testingwere trypsinized, resuspended and tested with the selective agent.

TGR testing was negative at both carbaryl concentrations. Addition of S9 microsomes or10 mM glutathione did not change this result, though cellular toxicity was decreased. Carbaryltreatment resulted in a dose-dependent increase in SCE; at ascending doses, the averagenumber of SCEs in cells with 21/22 chromosomes was 7.85±0.27, 10.00±0.47 and 15.06±0.44*(*p<0.01). The presence of S9 microsomes attenuated this response.

This study was considered to be supplemental.

5. Formation and genotoxicity / carcinogenicity of nitrosocarbarylEisenbrand et al. (1975) have examined the pH dependence of nitrosocarbaryl production fromcarbaryl and nititrite in vitro. 10-3 or 10-4 M carbaryl was incubated with a fivefold molar excess ofnitrite at 37°C in a closed vessel. The target pH values were maintained by addition of HCl orNaOH in a pH-stat, with the reaction stopped after 15 or 60 minutes by addition of amidosulfonicacid. After extraction with dichloromethane and roto-evaporation of the organic phase, the N-nitrosocarbaryl was quantitated colorimetrically against a prepared standard.

The carcinogenicity of N-nitrosocarbaryl was also examined in this study. Eight male and8 female Wistar rats received single subcutaneous injections of 1000 mg/kg N-nitrosocarbaryl,with 8 controls of unspecified sex treated with the Livio oil vehicle. N-nitrosocarbaryl was alsoadministered by gavage to 37 male and female rats (22 rats of either sex served as untreatedcontrols) at single doses ranging from 200 to 1500 mg/kg in 10% starch paste.

At 10-3 M carbaryl / 0.1 N HCl / pH 1, the conversion to N-nitrosocarbaryl was 1.2% and1.7% at 15 and 60 minutes, respectively. At pH 2 that conversion was 0.1 and 0.2%, while at pH3 it was 0.05 and 0.1%. In the presence of a stronger acid (1 N HCl - the pH was not specified),the conversion was 3.2% and 2.2%, with the decline at 60 minutes attributed to instability underthose conditions (maximum N-nitrosocarbaryl stability occurs at pH 3-5). At 10-4 M carbaryl / 0.1N HCl / pH 1, the conversion was 0.9% at 60 min.

Fifteen of the 16 animals treated subcutaneously with 1000 mg/kg N-nitrosocarbaryldeveloped tumors at the injection site, with 14 of those animals dying by day 450. One animalwas still tumor-free at 630 days. In contrast, the single oral administration produced no toxiceffects and no tumors through 21 months.

This study is considered supplemental.^^^^^^^^^^^^^^^^^^^^

Regan et al. (1976) investigated the ability of carbaryl and nitrosocarbaryl to induce DNA single-strand breaks in cultured human skin fibroblasts. The fibroblast DNA was labeled by overnightincubation with 3H-thymidine or with 32PO2. The labeled cells were incubated with 10-4 Mcarbaryl or 10-4 M NO-carbaryl for 1 hour followed by two washes in growth medium andassayed either immediately or after 20 hours of further incubation. 10,000 cells were layeredonto an alkaline sucrose gradient in 0.2 ml of 1 M NaOH, allowed to stand for 1 hour andcentrifuged for 3 hr at 30,000 rpm. Extracted DNA was also subjected to cesium chloride

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gradient centrifugation for 65 hours at 30,000 rpm.Sucrose gradient sedimentation profiles of cellular DNA, both immediately after and 20

hours after a 1-hour exposure to 10-4 M carbaryl, showed no differences from untreated cells.Similar treatment with NO-carbaryl, however, showed a marked decrease in sedimentation rateboth immediately after and 20 hours after exposure. This was interpreted as evidence forinduction of single-strand breaks or induction of alkali-labile bonds. A similar result was obtainedafter a 2-minute NO-carbaryl incubation. Further analysis generated a conclusion that the alkalibreaks occurred every 8-18x106 daltons. Cesium chloride analysis using 3H- and 14C-labeledNO-carbaryl suggested that the methyl residue, as opposed to the naphthalene ring residue,bound irreversibly to the DNA.

This study was considered to be supplemental.

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Table III-10. Genotoxic effects of carbaryl

Test type /system

Species /strain /culture

Dose or concentration S9 Result Comments / Reference

Gene mutation:Ames test, S.typhimurium(in vitro)

TA 1535,1537, 1538,98, 100

Trial 1: 0, 5, 10, 50, 100, 500,1000 µg/plate; Trial 2: 0, 10,50, 100, 500, 1000, 2000µg/plate

± Negative Acceptable a

Lawlor (1989)

Ames test, S.typhimurium(in vitro)

TA 98, 102,1535

0, 1, 5, 10, 50, 100, 500, 1000,5000, 10,000 µg/plate

± Negative Supplemental a

Grover et al. (1989)

CHO/HGPRT forwardmutationassay (invitro)

Chinesehamster ovarycells

2 trials, 0 - 0.3 mg/ml ± Negative AcceptableYoung (1989)

Ouabainresistance (invitro)

V79 Chinesehamsterfibroblasts

0.1 - 1000 µM - Positive SupplementalAhmed et al. (1977a)

Thioguanineresistance (invitro)

V79 Chinesehamsterfibroblasts

0, 50 or 100 µM ± Negative SupplementalOnfelt & Klasterska (1984)

Chromosomal aberration:Dominantlethalmutations (in vivo)

Rat #1: in feed at 0, 7, 25,100 or200 mg/kg/day#2: by gavage in corn oil at 0,3, 7 25 or 100 mg/kg/day#3: in feed containing corn oilat 0 or 100 mg/kg/day

n/a Negative SupplementalWeil (1972)

Aberrationtest (in vitro)

CHO-WBLcells

-S9: 0, 7.5, 10, 25, 50 or 75µg/ml +S9: 0, 150, 200, 250 or 300µg/ml

± -S9: Negative+S9: Positive

AcceptableMurli (1989)

Aberrationtest (in vitro)

Chinesehamsterfibroblasts

3 doses, including the 50%growth inhibition dose (max.effective dose = 0.03 mg/ml)

- Positive SupplementalIshidate & Odashima (1977)

Micronucleiin bonemarrowRBCs (invivo)

CD-1 mice 0, 50, 100 or 200 mg/kg/day(for two consecutive days)

n/a Negative Acceptable Marshall (1996)

Aberrationtest (in vivo)

Rootmeristems ofAllium cepa

0, 0.1, 0.4, 0.7, 1.0 or 1.3% ± b Positive SupplementalGrover et al. (1989)

Mitoticspindleabnormalities (in vitro)

V79 Chinesehamsterfibroblasts

0, 25, 50, 100, 200 or 400 µM - Positive SupplementalSoderpalm-Berndes & Onfelt (1988)

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DNA damage:UnscheduledDNAsynthesis (invitro)

SV-40transformedhuman cells(VA-4)

0, 1, 10, 100 or 1000 µM ± Positive ± S9 SupplementalAhmed et al. (1977b)

UnscheduledDNAsynthesis (invitro)

Primaryhepatocytesfrom Fischer344 rats

Trial 1: 0, 0.5, 1, 2.5, 5, 10, 25µg/mlTrial 2: 0, 5, 7.5, 10, 15, 20 or25 µg/ml

- Negative AcceptableCifone (1989)

Sisterchromatidexchange (invitro)

V79 Chinesehamsterfibroblasts

0, 50 or 100 µM ± Positive(particularly w/oS9)

SupplementalOnfelt & Klasterska (1984)

Protein andDNA bindingin liver (invivo)

CD-1 mice (%) 14C-carbaryl @ 75 mg/kgeither as a single dose or after13 days of 8000 ppm dietarycarbaryl

n/a Negative AcceptableSagelsdorff (1994)

a The designation "Acceptable" indicates that the study was successfully completed according to FIFRAguidelines. "Supplemental" indicates that the study was not conducted according to FIFRA guidelines;however, such studies were reviewed and considered to contribute to the general genotoxic picture of thechemical.b S14 microsomes from wheat seedlings were used in this study.

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F. REPRODUCTIVE TOXICITY

1. OverviewLaboratory animal studies from the older Russian literature (1965-1974) revealedhistopathologic changes in male reproductive tissues and sperm in various species afterexposure to carbaryl. Unfortunately, with two exceptions (the studies of Rybakova [1966] andShtenberg and Rybakova [1968], which are summarized below), these studies were notavailable in useful translation. Nonetheless, recent studies by Pant et al. (1995, 1996) using ratsexposed by gavage, were confirmatory. Several US-based studies have been negative for malereproductive and histopathologic effects, though they employed a dietary, as opposed to agavage, exposure regimen. This raised the possibility that the method of oral exposure is acrucial determinant for carbaryl toxicity in the male reproductive system. In addition, many of thelatter studies did not examine sperm morphology, making it impossible to determine thehistopathologic status of the reproductive system.

In light of these mixed results from laboratory animal studies, an early epidemiologicinvestigation of testicular function among carbaryl-exposed factory workers was undertaken(Wyrobek et al.,1981). This study was designed to determine if spermatogenic effects haveoccurred in human occupational settings. The results of Wyrobek's study suggested thatcarbaryl may induce spermatogenic toxicity. Furthermore, a more recent study of carbarylfactory workers from China showed statistically higher levels of sperm chromosomal aberrationsand DNA damage in an occupationally exposed population (Xia et al., 2005). In two studies,Meeker et al. (2004a and 2004b) noted an association between 1-naphthol levels in the urineand certain sperm toxicity parameters (decreased sperm concentrations, decreased spermmotility and increased DNA single strand breaks resulting in high Tail% in comet assays).However, it was not known for certain if the 1-naphthol originated as carbaryl or as napthalene.Possible reproductive effects of carbaryl were also considered in a recent epidemiologic studyof male pesticide exposure and pregnancy outcome among farm families in Ontario, Canada(Savitz et al., 1997). In that study, the adjusted odds ratio for miscarriage rose in conjunctionwith carbaryl exposure, suggesting that exposure of reproductive-aged males could result inclinically manifested toxicity.

All of these studies are summarized below and in Table III-10.

2. Human epidemiologic studiesWyrobek et al. (1981) examined semen samples for spermatogenic abnormalities from a cohortof 50 male carbaryl factory workers (current employees or former workers with at least one yearof factory experience) and 34 controls (workers providing samples as part of their pre-employment medical examinations). The men were assigned to one of three exposure groups:control (i.e., the new hires), low dose (supervisors, foremen, substitutes and maintenanceworkers) and high dose (full-time baggers and operators), though many of the comparisonswere made only between controls and exposed workers (i.e., low dose and high dosecombined). Rankings were also done according to (1) the number of years of work with carbaryland (2) whether or not the exposures were current or had occurred in the past (i.e., "previouslyexposed workers"). The latter group represented 19 of the 49 total exposed men analyzed forsperm morphology; these workers exhibited an average time since employment of 6.3±3.9years (range = 1-12 years).

The carbaryl air concentrations in the facility were not determined for this study, thoughair sampling data generated by the company’s industrial hygiene program provided an indicationof the range of values encountered. Thus three samples from the operations area yielded airconcentrations between 0.36 and 14.21 mg/m3 (mean = 4.9 mg/m3), 22 samples from the

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distribution area ranged between 0.03 and 1.8 mg/m3 (mean = 0.347 mg/m3), and 36 personalmonitoring samples from the same area ranged between 0.0 and 1.8 mg/m3 (mean = 0.439mg/m3).

A single semen sample was collected per participant after three days of sexualabstinence. Sperm counts and ejaculate volumes were determined. Sperm morphologic defectswere elucidated histologically on 500 fixed and stained sperm / sample. Fluorescence assayswere conducted to determine the number of sperm carrying double fluorescent bodies,considered evidence for the presence of two Y chromosomes (an abnormality likely due tomeiotic nondisjunction). Blood samples were collected to determine testosterone, FSH and LHlevels. The roles of possible confounding factors such as age, smoking, recent illness and drugintake were elucidated by multiple regression analysis. Correlations among semen parameters,blood parameters and personal histories were identified using correlation analysis.

Statistically significant differences between groups in sperm counts were not observed.For example, the mean count for entire control group was 128.7x106/ml (n=34), compared to140.7x106/ml (n=48) for the exposed group. Age-matched groups (18-40 yr) showed counts of 124.7x106/ml (controls, n=33) vs. 120.3x106/ml (exposed, n=26). However, a non-statisticallysignificant elevation of oligospermic individuals (i.e., those with sperm count < 20x106/ml) wasobserved in the exposed group (control = 2/34 vs. exposed = 7/48; p=0.1) which may havebiological significance.

There was an increase in the number of abnormally shaped sperm in the carbaryl-exposed population. For example, control samples for the entire 18-40 yr group showed41.8±2.2% of sperm rated as abnormal (n=33), while the parallel value for the 18-40 yr currentlyexposed samples was 57.9±3.4% (n=18; p<0.001). Similarly, control samples from the 18-40 yrgroup without confounding factors showed 42.0±2.7% of sperm rated as abnormal (n=22), whilethe parallel value from the 18-40 yr currently exposed samples without confounders was56.2±4.3 (n=14; p<0.01). The percentage of abnormal sperm in currently exposed men groupedin the high exposure group (n=19) was not appreciably different from currently exposed mengrouped with the low exposure group (n=11), though both groups differed from controls (n=34).

Among the 30 currently exposed workers examined, there was a significant negativecorrelation between the number of years exposed to carbaryl and the percent abnormal sperm(r= -0.42, p<0.025). The authors provided three possible explanations for this unexpectedfinding: (1) longer-term workers had graduated to less-exposed positions, (2) biologic orpharmacologic adaptation had occurred with the longer exposures (eg., repair processes hadbeen induced), and (3) over time, selection for less-affected males had occurred. None of theserationales were explored in the study.

The authors also recognized a statistically significant negative correlation between ageand percent abnormal sperm in the currently exposed group (r= -0.55, p<0.005). As the meanage of the carbaryl-exposed group (40.7±10.0 yr) statistically exceeded that of the controls(26.6±5.6 yr, p<0.001), the negative correlation between age and percent abnormalities wasstrong evidence that the higher age of the exposed group did not account for the increasedpercent abnormalities in that group. They note, in addition, that a statistically significantcorrelation between age and percent abnormal sperm was not seen among the controls(r=0.07).

Previously exposed workers, defined above as men with an average time since carbaryl-related employment of 6.3±3.9 years (range = 1-12 years), showed a somewhat higherincidence of abnormal sperm than controls, though this achieved statistical significance onlywhen the entire cohort was considered (i.e., when confounders were included). The proportionof teratospermic men, defined as those with greater than 60% abnormal sperm forms, rose inthe exposed population from 4/34 in controls to 9/30 in currently exposed and 5/19 in previously

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exposed men. When the two latter groups were combined, creating a teratospermic incidence of14/49, statistical significance was not achieved (p=0.06).

Assays for fluorescent bodies were conducted on semen samples from 17 highexposure men and 17 controls. While, as expected, these groups showed statistically differentpercent abnormal sperm percentages (41.2±2.5% in controls vs. 52.6±3.6% in high exposuregroup; p<0.01), there was no statistically significant difference in percent sperm with twofluorescent bodies (0.8±0.2% in controls vs. 1.0±0.3% in exposed) nor in percent sperm withone fluorescent body (44.7±0.9% in controls vs. 44.3±1.0% in exposed).

Attempts to correlate sperm abnormalities, sperm with double fluorescent bodies, FSH,LH and testosterone, failed. However, a correlation was seen between exposed men with spermcounts of less than 80x106 sperm/ml and percent abnormal sperm. There were 18 men in thesub-80x106/ml category, showing 64.0±3.8% abnormal sperm vs. 29 men in the plus-80x106

sperm/ml category, who showed 43.6±1.8% abnormal sperm, p<0.01. While this correlation didnot track carbaryl exposure history, it did suggest a relationship between shape abnormalitiesand sperm counts.

These data reveal a correlation between the percent abnormal sperm and exposure tocarbaryl under occupational circumstances. It is unclear if the extent of this effect would lead toreproductive or teratogenic problems in individuals, though the authors cite other studies inhuman populations that correlate spontaneous abortions, reduced sperm counts and markedincreases in sperm abnormalities. The strength of this study was limited by small group sizes,imperfect knowledge of the actual exposure concentrations and the possibility that unknownxenobiotics played a role in the exposed cohort. Nonetheless, these results are considered toreflect a carbaryl-mediated effect, especially as several possible confounders were pursued andeliminated.

********************

Savitz et al. (1997) examined pregnancy outcomes in Ontario farm families as a function of farmactivities or pesticide exposures that occurred to the adult husbands within 3 months ofconception. This time window was appropriate for capturing effects mediated indirectly throughdamage to sperm. Pregnant mothers older than 44 years were not included. Using the 1986Canadian Census of Agriculture, 2946 couples from 2693 eligible farms were identified, with3984 pregnancies ultimately examined.

Exposure was classified using a self-administered activities checklist which includedreference to the use of specific pesticides (including carbaryl) by the husbands. A judgementwas made concerning the plausibility of direct pesticide exposure exceeding one month. Apositive judgement led to a classification as “exposed”. Four possible pregnancy outcomes wereenumerated: miscarriage, small for gestational age (SGA), preterm delivery and sex ratio. Oddsratios were calculated using the group of men with “no activity” or “no chemical activity” as thereferent populations.

Carbaryl usage, when combined with activities defined generally as “crop herbicideapplication”, produced an adjusted odds ratio of 1.9 for miscarriage (95% confidence limits, 1.1-3.1). If carbaryl usage was combined with the reporting category of “application of cropinsecticides and fungicides”, the adjusted odds ratio rose to 2.1 (95% confidence limits, 1.1-4.1).“Application of crop insecticides and fungicides” alone (i.e., without carbaryl usage) resulted inan adjusted odds ratio of 1.1 (0.8-1.6). Combination of carbaryl usage with use of “yardherbicides” produced an adjusted odds ratio of 1.3 (95% confidence limits, 0.6-2.5). None of theother pregnancy outcome parameters was associated with an elevated odds ratio.

While the odds ratios were consistent with a role for carbaryl-induced sperm damage inmiscarriage, the exposure conditions were not well understood and the reported odds ratio

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ranges too great to establish clear effects. Consequently, the usefulness of this study in a riskassessment context was limited to providing support for other data that provide a clearer link togenotoxic or male reproductive effects.

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Meeker et al. (2004a) studied the relationship between urinary levels of 1-naphthol (1N, aprimary carbaryl metabolite as well as a metabolite of napththalene) and various spermparameters in humans. Subjects were recruited from a pool of 330 men seeking diagnoses froma Boston infertility clinic. They were primarily white (82%), 36.2±5.5 years, 72% never havingsmoked. Subjects were excluded if they had highly concentrated or dilute urine samples asdetermined by creatinine concentrations or specific gravity. The chlorpyrifos metabolite 3,5,6-trichloro-2-pyridinol (TCPY) was also measured, though those results will not be discussedhere.

The parameters measured included sperm concentration, motility and morphology. Themorphologic parameters were generated using 200 sperm / donor under the “Tygerberg StrictCriteria”. The motion parameters were measured by computer-aided semen analysis (CASA),incorporating the following outcomes: VAP (mathematically smoothed velocity) and VSL(straight line velocity) - both measures of sperm “progression” - and VCL (curvilinear velocity),ALH (amplitude of lateral head displacement) and BCF (beat cross frequency), measures ofsperm “vigor”. Several of the motion parameters were combined to portray “straightness” (STR= [VSL÷VAP] x 100) and “linearity” (LIN = [VSL ÷ VCL] x 100).

Odds ratios (OR) for spermatotoxicity increased when comparing dichotomized spermparameters from men in the lowest 1N urinary tertile with those in the middle and high tertiles.For example, ORs for below-reference sperm concentrations were 1.0#, 4.2* and 4.2* atincreasing 1N urinary tertiles (*p<0.05; #p<0.01 for trend). ORs for sperm motility were 1.0#, 2.5*and 2.4* (*p<0.05; #p<0.01 for trend). No statistically significant effect was seen on spermmorphology, though there was a suggestion of an effect: 1.0, 1.4 and 1.6.

Of the CASA motion parameters examined, a statistically significant inverse associationwas identified for urinary 1N and VSL (regression coefficient = -1.64; p<0.02). Inverseassociations also existed for VCL (-1.98) and LIN (-0.79), though statistical significance was notattained.

The strengths of the study resided in its size, high participation rate and the use ofbiologically relevant markers of exposure. Weaknesses included the inability to unambiguouslyidentify carbaryl as the source of 1N and the use of a single urinary sample to estimate the 3-month carbaryl (or naphthalene) exposure. However, with respect to the latter, the authors citetheir own in press study showing that this was indeed a valid indicator of exposure. In addition,it was difficult to know if the subject population, which consisted of men seeking diagnoses fortheir infertility, biased the results. In any event, it appears that an interquartile increase inurinary 1N level may be associated with a 4% decrease in sperm motility. This could generatean increase in subfertile men among those whose sperm are already trending toward the bottomof the motility spectrum.

In a parallel study, Meeker et al. (2004b) tracked DNA damage in human sperm as a function of1-naphthol and TCPY concentrations in the urine (TCPY is a metabolite of chlorpyrifos; as in theprevious study, the TCPY results will not be summarized here). DNA damage was assessedusing a modified "comet" assay, which is based on the electrophoretic distances traveled bynegatively-charged DNA molecules from single sperm cells toward a positive electrode. Thesemovements form a characteristic comet tail, the shape of which is indicative of toxic damagedue to the creation of DNA fragments, etc. Two hundred and sixty subjects were recruited from

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a pool of 368 men seeking diagnoses in a Boston infertility clinic. They were primarily white(82%), with a mean age of 36.1±5.6 years. 74% of the cohort had never smoked, while 9% werecurrent smokers. Subjects were excluded if they had concentrated or dilute urine samples. Thiswas determined primarily by urinary specific gravity measurements, but also by urinarycreatinine concentrations. Of the original subject pool, there were 19 azoospermic men (i.e.,semen with no sperm cells) among a total of 74 subjects whose semen was, for variousreasons, not analyzed. 1N was determined in a single urinary sample from each subject.

The comet assays were performed under neutral conditions with 50 µl semen-agarosemixtures embedded between additional layers of agarose on electrophoretic glass slides. Afterdissolving the cell membranes in lysing solution and treating with RNase and proteinase K todissolve chromatin, the slides were subjected to electrophoresis for 1 hr, fixed, dried, stainedand observed under a fluorescence microscope. Comet tail parameters, including comet extent,tail distributed moment (TDM; an integrated measure of the distance and intensity of cometfragments) and percent of the total DNA in the tail (Tail%), were established for 100 sperm /sample using specialized computer software. Cells with tails greater than 300 µm were too longto analyze with the software. As this condition (CHD) was considered to result from severe DNAdamage, such cells were enumerated and used as an additional measure of DNA damage.

A highly statistically significant association was found between Tail% and 1N: theregression coefficient was 4.13 (p=0.0003; 95% confidence limits, 1.92-6.32). Thus for aninterquartile range increase in 1N, the Tail% significantly increased by 4.13%. Regressioncoefficients were negative for comet extent and TDM, but they did not achieve statisticalsignificance. However, stratifying the data by comet extent revealed a statistically significantnegative association between Tail% and TDM. This suggested that there was at least someassociation between 1N and TDM. However, the apparent inverse relationship was unexpected.Since TDM is an integrated value (dependent both on distance and intensity), the authorsspeculated that it may reflect the type of DNA damage that occurred. For example, a cell thathas high Tail% and low TDM may reflect a predominance of single strand breaks, while a cellwith low Tail% and high TDM may reflect a predominance of double strand breaks. The authors'analysis suggests that carbaryl produces single strand breaks resulting in high Tail%.

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Xia et al. (2005) examined the question of whether carbaryl exposure to workers in a pesticidefactory in Changzhou, China disposed them to spermatotoxicity. The study included a total of 46sperm donors, age 21-48 years, all nonsmokers and nonregular drinkers. Sixteen were carbarylworkers who had both worked in the plant for more than 1 year and had worked therecontinuously for the 6 months prior to sampling. An internal control group of 12 individualsworked in the same complex, but were isolated from the pesticide facility. An external controlgroup of 18 individuals with no history of carbaryl exposure came from other professions. Therewere no significant age or work year differences between groups.

The following sperm parameters were gauged: semen volume, sperm concentration,sperm number, sperm motility (using the CASA program referred to above in Meeker et al.,2004a) and sperm morphologic abnormalities (using fixed and stained sperm). Modified TUNELassays (deoxy-nucleotidyl transferase-mediated dUTP-biotin nick end-labeling) were performedto determine the percent DNA fragmentation. Multicolor FISH assays (fluorescence in situhybridization) were performed to detect chromosome aberrations on the X and Y chromosomesand on chromosome 18 using DNA probes specific to the centromeric regions.

No significant differences were noted for semen volume, sperm concentration, spermnumber and sperm motility. Morphologic abnormalities did exhibit a statistical increase, with20.50±6.71% among internal controls, 15.92±7.58% among external controls and

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25.25±4.90%** among the carbaryl-exposed group (**p<0.01 compared to external controls).This was due primarily to statistically significant increases in head abnormalities (9.85±5.12%vs. 7.56±3.61% vs. 11.72±4.93%*; p<0.05) and tail abnormalities (8.73±4.10% vs. 6.60±4.78%vs. 10.82±3.09%**).

TUNEL assays showed a statistically significant increase in the percentage of cells withfragmented DNA in the carbaryl-exposed population: 13.36±12.17% in internal controls,13.92±7.15% in external controls, 21.04±8.88%* in the carbaryl-exposed group (p<0.05compared to both internal and external controls).

Disomic sperm appeared to increase in the carbaryl-exposed group as revealed in theFISH assays. Thus the percentage of XY18 sperm in internal control, external control andcarbaryl-exposed groups was 0.280±0.076%, 0.177±0.080% and 0.281±0.102%** (p<0.01compared to external controls). The percentage of YY18 sperm was 0.134±0.052%,0.079±0.042% and 0.185±0.083%** (p<0.01 compared to external controls; p<0.05 compared tointernal controls). The percentage of X1818 sperm was 0.093±0.053%, 0.051±0.028% and0.113±0.070%* (p<0.05 compared to external controls). The percentage of Y1818 was0.076±0.031%, 0.052±0.043% and 0.119±0.055%** (p<0.01 compared to external controls;p<0.05 compared to internal controls).

The FISH assays also revealed a possible increase in nullisomic sperm in the carbaryl-exposed group. The percentage of sperm nullisomic for sex chromosomes in internal control,external control and carbaryl-exposed groups was 0.383±0.099%, 0.277±0.077% and0.426±0.174%** (p<0.01 compared to external controls). The percentage of sperm nullisomicfor chromosome 18 was 0.222±0.062%, 0.139±0.043% and 0.268±0.126%* (p<0.05 comparedto internal controls).

These results were consistent with a role for carbaryl in the induction of chromosomalaberrations and DNA fragmentation in human sperm. Carbaryl also appeared to be associatedwith an increased incidence of men with sperm morphologic abnormalities.

3. Laboratory animal studiesa. Contract laboratory studies

A two-generation reproductive toxicity study in CD rats was conducted by Tyl et al. (2001). F0animals, 30/sex/dose (enough to yield at least 20 pregnant rats/dose), received carbaryl (99.1%purity) in the feed for 10 weeks at doses of 0, 75, 300 and 1500 ppm ad libitum. Calculatedcarbaryl intakes for the F0 and F1 parental animals were 5-6 mg/kg/day at 75 ppm, 21-36mg/kg/day at 300 ppm and 92-136 mg/kg/day at 1500 ppm. The pre-breeding period wasfollowed by a 2-week mating period within treatment groups, with exposure continuing, toproduce the F1 generation. F0 males were necropsied at the time of delivery. F1 litters wereculled to 10 on postnatal day (pnd) 4 and weaned on pnd 21, at which time the F0 females werenecropsied along with up to 3 F1 weanlings/sex/litter. Thirty F1 parental animals/sex/dose werethen chosen to produce the F2 generation. They were exposed to dietary carbaryl at the samedoses for 10 weeks, mated within their dose groups over a 2-week period, and the F1 parentsand F2 pups sacrificed and analyzed over the same time spans as for the previous generation.Standard observations were made at appropriate intervals for clinical signs, body weightchanges, feed consumption, reproductive performance, reproductive system histology /histopathology and organ weights.

There were no treatment-related clinical signs in either sex. Precoital and gestationalperiods were comparable among groups of both generations. Mean estrus cycle length wasslightly longer in F0 females at 1500 ppm (4.77 days) compared with controls (4.59 days), but (1) the effect was not statistically significant, and (2) estrus cycle lengths among F1 females

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were similar across dose groups. In light of the human epidemiological studies, the olderRussian studies, and those of Pant et al. (1995, 1996), all summarized in this section, it ispertinent to mention that there were no effects on F0 or F1 parental epididymal sperm counts,motility, morphology, homogenization-resistant spermatid head counts, daily sperm productionor efficiency of daily sperm production.

Food consumption among F0 males was slightly decreased at 1500 ppm, with someintervals showing statistical significance when expressed on a g/day basis. However,consumption on a g/kg/day basis was similar across dose groups. F0 females showed nodifferences in food consumption. Similar to the F0 males, F1 males showed lower g/day foodconsumption at 1500 ppm, though g/kg/day consumption was actually higher. The same wastrue for F1 females.

Mean pre-breeding body weights were consistently statistically suppressed at 1500 ppmamong F0 and F1 animals of both sexes. These were largely reflective of statistical decrementsin weight gain during the first pre-breeding week of exposure (Table III-11). There was alsosome indication that weight gains among the 300 ppm animals were suppressed, particularlyamong F1 males. Maternal body weight gains were suppressed at 1500 ppm in both the F0 andF1 generations, though lactational weight gains appeared little affected, or were increased, bycarbaryl exposure. Mean F1 and F2 pup body weights tended to be suppressed at 1500 ppm,particularly as the lactational period progressed (Table III-11, pup body weights, postnatal days0 and 21).

Pup survival measurements indicated possible treatment effects at 300 and 1500 ppm.Though the data were not as statistically robust as the body weight data, statistical linear trendswere detected in survival indices for F1-day 14 pups, F2-day 4 pups and F2-day 7 pups (Table III-11). The mean number of live pups / litter, F1-pnd 4 (precull) did not appear affected. However,the same parameter for the F2 pups was statistically depressed at the mid and high doses(Table III-11).

Both male and female F1 pups appeared to sustain statistically significant developmentaldelays at 1500 ppm. In males this was represented by a delay in the time of preputialseparation, while in females it was represented by a delay in vaginal opening (Table III-11).Because the F2 pups were sacrificed at weaning, similar measurements were not made forthem. However, anogenital distance measurements on F2 pups did not suggest an effect.

Necropsies on parental animals and pups, F0- F1-F2, did not reveal treatment-relatedeffects.

The parental NOEL was set at 75 ppm (5-6 mg/kg/day), based on reduced body weightgains at 300 and 1500 ppm. Because no effects on reproductive indices were detected, thereproductive NOEL was set at >1500 ppm (92-136 mg/kg/day). The pup NOEL was set at 75ppm, based on increased pup mortality, reduced body weights and delayed developmentalindices at 1500 ppm and increased F2 mortality, pnd 0-4, at 300 and 1500 ppm. Thiscorresponded to a parental intake of 5-6 mg/kg/day, though nothing is known of the carbarylintake in the pups (carbaryl concentrations in milk were not determined).

This study was acceptable by FIFRA guidelines.

Table III-11 . Effect of dietary carbaryl on reproductive parameters in CD rats (Tyl et al., 2001)

Carbaryl concentration in diet (ppm) a

0 75 300 1500

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Body wt. gain, pre-breeding days 0-7 (g)F0 % F0 & F1 %F1 &

58.924.564.640.1

58.624.563.140.4

54.623.4

58.6*37.8

45.2**17.9***54.2**36.3*

Body wt. gain, gestation days 0-20 (g)F0 &F1 &

138.1140.1

130.2137.2

132.0134.3

121.0***115.3***

Body wt. gain, postnatal days 0-21 (g)F0 &F1 &

9.38.5

3.35.7

12.610.8

14.415.8

Pup body wts. (g)F1, postnatal day 0F1, postnatal day 21F2, postnatal day 0F2, postnatal day 21

6.3448.796.27

50.91

6.6849.466.51

52.30

6.4150.736.58

49.68

6.0943.46***

6.0040.39***

Pup survival index (%)F1, 4-dayF1, 7-dayF1, 14-dayF2, 4-dayF2, 7-dayF2, 14-day

98.499.799.7+

98.3++

100.0+

98.6

99.1100.0100.098.799.699.6

95.099.699.292.096.094.8

98.199.395.488.993.096.6

Mean live pups / litter (precull)F1, postnatal day 4F2, postnatal day 4

13.915.4++

13.313.9

13.912.7*

14.312.5**

Pup developmental indicatorsF1 %, day of preputial separation b

F1 &, day of vaginal opening b41.630.6

41.531.3

41.731.3

43.7**32.0**

*, **, ***: p<0.05, 0.01, 0.001+, ++: p<0.05, 0.01 (trend test)a Calculated carbaryl intakes for the F0 and F1 parental animals were 5-6 mg/kg/day at 75 ppm, 21-36mg/kg/day at 300 ppm and 92-136 mg/kg/day at 1500 ppm.b Because the F2 pups were sacrificed at weaning, similar developmental measurements were not madefor them.

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b. Studies from the open literature - oral gavage exposureRybakova (1966) studied the effects of gavage dosing with carbaryl (100% purity) in rats(“mixed albino”) and mice (acute only; strain not stated). Control animals were treated with thevehicle, sunflower oil. Acute, subchronic and chronic exposure regimens were employed. Asmany of the observed effects involved reproductive tissues, this study is most relevant to thissection of the RCD.

Acute. The LD50 for female rats and mice was 437.5±70.6 mg/kg and 515±79.2 mg/kg,respectively. Clinical signs were not reported.

Subchronic. Male and female rats (32/sex/dose) were treated by gavage with 0 and 50mg/kg/day carbaryl for 50 days. The following effects were noted in exposed animals: (1) 8-

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10% weight gain decrement, (2) decrements in butyrylcholinesterase (27%) andacetylcholinesterase (41%; the tissue of origin was not stated), (3) significant decrease inadrenal ascorbic acid levels (amount not stated; p<0.001), (4) 40.4% mean decrease inspermatozoa motility, (5) 11.3% mean delay in the estrus cycle, (6) 50% mean prolongation ofdiestrus, (7) a decrease in the “period of heat” from 1.34 to 1.05 days, (8) increase in theexcretion of gonadotropic hypophyseal hormones was reported in immature mice, thoughneither the causative dose nor the specific hormones was reported, (9) adrenal and liverweights were increased by 20% and 28%, respectively.

Chronic. In the chronic phase of this study, 24 rats/sex/dose were treated by gavagewith carbaryl at 0, 7, 14 and 70 mg/kg/day for 12 months. Toxicity testing was performed at 3, 6,9 and 12 months. The following observations were made: (1) no overt toxicity, (2) 6-8%decrement in weight gain at the low and mid doses, with the high dose generating a “statisticallysignificant loss of weight (p<0.001) throughout the experiment” (data not provided), (3) meancholinesterase activities decreased by 3.3%, 32.5% and 94% at 12 months (tissue of origin notstated), (4) 15-30% increase in adrenal weight at the low and mid doses and a 43% rise at thehigh dose, paralleled by a dose-dependent expansion of the zona glomerulosa, with unusualmitotic patterning, (5) adrenal ascorbic acid levels lowered by non-statistically significantamounts, (6) sperm motility inhibited in a dose-dependent fashion, achieving statisticalsignificance at the mid and high doses at 6 and 9 months, and at all three doses at 12 months(% inhibition of motility at 6 months at increasing doses: 5%, 13%**, 40%***; 9 months: 7%,16%**, 56%***; 12 months: 22%***, 36%***, 74%***; **,***p<0.01, 0.001), (7) seminiferoustubules with a dose-dependent edema of the interstitial tissue, desquamation of thespermatogenic epithelium and destruction of the parenchyma, (8) estrus cycle lengthsincreased by 10%, 20% and 70%, resulting from increases in the diestrus phase length, (9)increased number of corpora lutea and atretic follicles (data not provided), (10) a bioassaysuggested that carbaryl exposure increased the secretion of gonadotrophic hormones (fewdetails provided), (11) other histopathologic effects noted in liver and kidneys.

While many effects were indicated by this study, very little actual data were provided.Nonetheless, the evidence for reproductive toxicity was supportive of similar findings from otherstudies (particularly oral gavage studies) and thus considered relevant in the current context.

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Shtenberg and Rybakova (1968) administered carbaryl (100% active material) by oral gavage toalbino rats (strain not identified) on a daily basis for 12 months. Doses were 0 (vehicle andvolume not identified), 7, 14 or 70 mg/kg/day. Initial examinations were followed by observationsconducted at 3-month intervals. The following parameters were evaluated: survival, generalhealth, motor activity, body weight, blood butyryl- and acetylcholinesterase, duration ofspermatozoal motility, status of the estrus cycle (vaginal smears), gonadotropic function,terminal adrenal, thyroid and reproductive organ histology, adrenal lipid content, thyroidfunction, pituitary (hypophyseal) glucoprotein analysis, and stress testing (by fasting) attermination.

Statistically significant body weight gain decrements were detected “throughout theexperiment” at 14 and 70 mg/kg/day (p<0.001), but not at 7 mg/kg/day (data not provided).Blood butyryl- and acetylcholinesterase were inhibited from the first measurement at 3 months.

The “duration of spermatozoal motility” was statistically suppressed at the two highdoses at 6 and 9 months, and at all three doses at 12 months (duration of motility at increasingdoses, 12 month assay: 40.6, 31.5***, 25.8***, 10.6*** min). Histopathologic changes, observedin the testes at all doses in a dose-dependent fashion, included edema of interstitial tissue,destruction and desquamation of germinal epithelium and reduction in the number of

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spermatocytes and spermatids.Gonadotropic function was evaluated in a bioassay involving the injection of

homogenized pituitary glands from treated animals into immature recipient mice. According tothe report (p. 464), “whereas the hypophyseal homogenate from rats given carbaryl at a level of7 mg/kg/day for 12 months increased the weight of the ovaries and uterus in immature recipientmice by an average of 23 and 49%, respectively, the hypophyseal homogenate from rats given70 mg carbaryl/kg increase the weight of the ovaries by 51.5% and of the uterus by 123%compared with the weight of these organs in control mice.” The report goes on to claim thathistology of hypophyses from treated rats showed evidence of increased cell size, loss ofgranules and hyalinization of the cytoplasm. The authors feel that these changes were at theroot of the observed reproductive gland disturbances.

Histopathologic changes in the adrenal glands of rats receiving 7 mg/kg/day were alsoreported (p. 464): “an increase in the size and mitotic activity of cells in the zona glomerulosa.Enlarged cells, either binuclear or containing a large nucleus, were present in the fascicularzone. There was also an increase in lipids compared with the controls.”

By 3 months, the length of the estrus cycles in high dose females was statisticallyincreased. By 6 months, both mid and high dose animals had statistically longer cycles, asituation that was maintained through 12 months (estrus cycle length, 12 months: 4.56, 5.07,5.81** and 7.75*** days; **, ***p<0.002, 0.001).

Absorption and excretion of 131I in the thyroid was also impaired by carbaryl exposure,indicated “by a reduction in the rate of absorption and excretion of 131I and its rather lowrecovery, in comparison with the controls. Thus at the two lowest dosage levels, 131I-absorptionreached a peak within the first 4-6 hr and represented on average 16% of the administered 131I.In contrast, corresponding figures in the control group were 2-4 hr and 18%, while in animalsgiven 70 mg carbaryl/kg/day the peak of 131I-absorption was reached only after 20 hr andrepresented 10.2% of the administered dose. After 24 hr, rats on the two lowest dose levels hadabsorbed, on average, 10.5-9.6% of 131I, as against 10.4% in the controls. In contrast, rats onthe highest level had absorbed much less iodine (only 6.8%; p<0.001). After reaching a peak,thyroid activity began to decrease gradually. The slower rate of 131I-absorption at the 70mg/kg/day level may be regarded as an indication of a decrease in the functional activity of thethyroid. In the thyroids of these animals, the follicular epithelium in the central areas wasflattened, follicles were enlarged and the colloid was more dense and basophilic... In theperipheral areas, changes in the follicular epithelium and colloid were less pronounced. At the 7and 14 mg/kg/day levels, too, the structure of thyroid tissue differed from that of the controls,although to a lesser degree than in the rats receiving 70 mg/kg/day.” (pp. 464-466).

The authors hypothesize that the endocrine effects noted in this study may have beensecondary to effects on the pituitary gland. The (subchronic) LOEL for this study was 7mg/kg/day, based on reduced sperm motility, effects on hypophyseal and thyroid function, andhypophyseal, adrenal and thyroid histopathology. A NOEL was not set.

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Dikshith et al. (1976) treated male albino rats (strain not stated, though they originated in acolony maintained by the Industrial Toxicology Research Centre, Lucknow, India) with carbaryl(99.0% pure) by oral gavage at doses of 0 (1 ml peanut oil) and 200 mg/kg, 3 days/week, for 90days. There were 7 animals/dose. Histopathologic analysis was conducted on liver, kidney,testes and epididymis. Biochemical analysis was also conducted as follows: liver and testes -succinic dehydrogenase, adenosine triphosphatase, alkaline phosphatase and acidphosphatase; liver - glucose-6-phosphatase; brain and blood - AChE. A further 7 animals/dosewere mated with unexposed females after the 90-day exposure period. When the females were

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deemed pregnant (by examination of vaginal smears for sperm), they were separated andallowed to complete the pregnancy. Litters were evaluated for weight and numbers of pupsborn. Pups were observed for 10 days post partum.

Though one animal each from the control and treated groups died on days 18 and 32,respectively, there were no signs of carbaryl-induced toxicity in any animal throughout the study.The report further states (p.163) that (1) “there were no gross abnormalities in the liver, kidney,testis, and epididymis of the experimental rats” and (2) “microscopic examination of theseorgans also did not present significant histological changes”. However, one of the micrographsshowed a testicular tubule from a treated rat apparently filled with debris along with a moregeneral enlargement of the interstitium (Fig. 4, p. 166). It is not clear from the report thathistopathology was actually carried out on control tissues.

The following enzymes showed statistically significant changes when assayed after the90-day period (*p<0.05; **p<0.01; ***p<0.001): testis - succinic dehydrogenase (control vs.treated, 2.96±0.17 vs. 3.49±0.13* nm/min/mg protein), adenosine triphosphatase (72.31±1.61vs. 83.43±3.83* nm/min/mg protein); liver - glucose-6-phosphatase (83.08±4.25 vs.100.16±5.41* nm/min/mg protein); blood - AChE (8.15±0.45 vs. 5.30±0.56*** µmol/ml/10 min); brain - AChE (0.96±0.02 vs. 0.85±0.04* µmol/100 µl of 10% homogenate/10 min).

Though no data were provided, the report states that there were no significant effects onthe rate of pregnancy, litter size, number of offspring born, or on pup health and viability through10 days.

The report minimizes the importance of any of the histological or biochemical changesnoted above. It does not explain the apparent pathology noted in the abovementioned testicularmicrograph. While it is possible that gavage treatment of male rats did not precipitate overteffects on fertility or pup viability, it is unclear why such a high dose (200 mg/kg; i.e., very nearthe LD50), provided 3 times per week over a 90-day period, did not result in clinical signs. Sinceno analytical data were available, one cannot be sure of the actual dose delivered.

This report has clear inadequacies in data reporting and analytical analysis. It is includedhere because it specifically examined male rat reproductive tissues after gavage treatment withcarbaryl.

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Kitagawa et al. (1977) treated four male Wistar rats by gavage with carbaryl (purity not stated).The dose was applied for one year at 3 mg/rat/week (it is assumed that this was done with asingle weekly dosing, though the actual dosing regimen was not stated in the report). With anapproximate weight of 200 g at the start of the study, this would have been equivalent to about15 mg/kg/week, or about 2 mg/kg/day if administered daily (though the report did not providethis information). Four control rats were gavaged with physiological saline (volume notprovided). The pancreas, adrenal gland and testis were analyzed for histopathologic changesfollowing sacrifice.

Examination of the testicular slides indicated “an obvious reduction in the number of thecells in the seminiferous tubules, especially in spermatogonia and in spermatozoa” (p. 55.) Amicrograph from a treated and from a control testis seemed to support this statement, thoughthe prevalence of the effect (i.e., the number of animals affected vs. controls) was not reported.There also appeared to be a reduction in the number and size of Langerhans islets in thepancreas. Effects on the adrenals were unremarkable.

A summary of this study was included here because of the attempt to detect testicularhistopathology, which is relevant to the discussion of potential carbaryl-induced reproductiveeffects.

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Narotsky and Kavlock (1995) examined the possible reproductive and developmental effects ofcarbaryl (purity, 99%), along with nine other xenobiotics, in pregnant Fischer 344 rats. Animalswere treated by gavage between gestation days 6-19 inclusive. Carbaryl doses were 0 (corn oilvehicle, 21 rats), 78 (16 rats) and 104 (16 rats) mg/kg/day. The high dose was selected basedon companion study which provided evidence for toxicity in nonpregnant females. The low dosewas set at 75% of the high dose. The animals were observed throughout the study for toxicity.Maternal body weights were determined on gestation days 6, 8, 10, 13, 16 and 20. Pups wereexamined and counted on post natal days 1, 3 and 6, and collectively weighed on post nataldays 1 and 6.

Tremors, motor depression and lacrimation were noted, usually during the first threedays of treatment, while jaw clonus (repetitive contractions) occurred throughout the treatmentperiod. As the dose levels corresponding to these signs were not explicitly reported, it isassumed that they occurred at both treatment doses. The first two days of treatment resulted instatistically significant weight losses at both doses (data were only expressed graphically;weight gains at 0, 78 and 104 mg/kg/day were ~2.5, ~-8*** and ~-9*** g, respectively;***p<0.001), while the gestation day 6-20 period produced a statistically significant decrement atthe low dose and a statistically significant loss at the high dose (~16.5 g, ~8 g** and ~-1.5 g***;**,*** p<0.01, 0.001). Pup weights were suppressed by ~6% at the high dose on postnatal day 1(p<0.001). By pnd day 6 there were no statistically significant differences among dose groups,though the mean high dose litter weights were ~5% less than controls. Two of the 13 pregnantdams (15%) sustained complete resorption at the high dose.

In this study, the observed developmental toxicity of carbaryl occurred at doses thatinduce parallel maternal toxicity.

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Pant et al. (1995) administered carbaryl (99.2% purity) by oral gavage to male Wistar rats on a5-days/wk basis for 90 days. The doses were 0 (0.2 ml peanut oil), 50 or 100 mgcarbaryl/kg/day, 8 rats/dose. After terminal sacrifice on day 91, the reproductive organs wereremoved and weighed. One testis/rat was preserved for histopathology, while the other washomogenized for assay of testicular enzymes. Sperm counts and motility determinations werecarried out using epididymal sperm.

Carbaryl-exposed rats were reportedly lethargic, though no details were provided as todoses, timing or numbers of animals affected. Body weights were reportedly statisticallydepressed by 60 days at the high dose, showing a >20% deficit by day 90 (data were onlypresented graphically). No effects on testicular, accessory sex organ or epididymidal weightswere observed, though again, actual data were not provided.

Testicular glucose-6-P-dehydrogenase (associated with premeiotic germ cells) andsorbitol dehydrogenase (associated with pachytene spermatocyte maturation) were suppressedat the high dose (G6PDH activities at ascending doses: 89.1, 79.1, 26.3* nmol/min/mg protein;SDH: 3.18, 2.94, 1.63*; p<0.05). Testicular lactate dehydrogenase (associated with germlineelements of the testes; inversely proportional with sperm maturation) and (-glutamyltranspeptidase (marker enzyme for Sertoli cell function) were statistically increased at bothdoses (LDH: 244, 390*, 500* nmol/min/mg; (GT: 23.2, 37.3*, 58.3*).

Total epididymal sperm counts and percent sperm motilities were statistically decreasedat both doses (sperm counts/epididymis: 10x107, 6x107*, 4x107*; sperm motility: 89.5%, 67.5%*,33.1%*). The total percent sperm abnormalities were increased at both doses (18.7%, 46.3%*,56.0%*), reflecting increases for each type of abnormality (banana head, detached head, neckcurved, curved, bent, tail round, tail short, tail looped).

9 Data for the parameters discussed in the summary of the Collins et al. study in gerbils are asfollows:

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Carbaryl caused several histopathologic changes in the testes. These includedcongestion, edema, depressed spermatogenesis and accumulations of cellular and acellularmasses in the seminiferous tubular lumen.

The LOEL for subchronic toxicity was <50 mg/kg/day, based on testicular enzyme,sperm and testicular histopathologic changes. This study was considered to be supplemental.

Pant et al. (1996) conducted a follow-up study to establish a NOEL for spermatotoxic effects inthe rat and to determine if young rats were more susceptible to such effects than older rats. Sixyoung and 6 old male Druckrey rats/dose were exposed by gavage to carbaryl (99.2% purity) at0 (0.2 ml peanut oil), 25, 50 or 100 mg/kg/day, 5 days/week, for 60 days. Body weights weredetermined at initiation and at terminal sacrifice (day 61), after which the reproductive organs(testes, epididymides, seminal vesicles, ventral prostate and coagulating glands) were removedand weighed.

The authors state that no overt toxicity was detected and that weight gains weresuppressed at 50 and 100 mg/kg/day, though the actual data were not supplied. The young ratsexhibited statistically significant absolute weight deficits at 100 mg/kg/day for the testes,epididymides, seminal vesicle, ventral prostate and coagulating gland, though again, the datawere not provided. This was apparently not the case for the adult rats. Relative weight deficitswere not observed in either the adult or the young rats.

Effects on sperm parameters were seen only at 50 and 100 mg/kg/day, and may havebeen severe in the young rats, though the data on this aspect were not robust. Sperm countsper epididymis in young rats were, at ascending doses, 8.0x107, 8.2x107, 6.0x107* and 5.0x107*(p<0.05). In older rats they were 8.0x107, 8.5x107, 7.0x107*and 6.0x107*. Percent motile spermin young rats was 86.0%, 85.0%, 65.0%* and 49.1%*, while in older rats it was 88.3%, 85.8%,75.0%* and 65.0*. Percent abnormal sperm in young rats was 10.5%, 11.3%, 19.8% and33.7%, while in older rats it was 10.3%, 11.1%, 16.1% and 23.1% (apparently statisticalsignificance was not achieved). According to the report, some abnormalities (bent up or downacrosomes) appeared only in the younger rats.

The NOEL for damage to the male reproductive system was set at 25 mg/kg/day, basedon a LOEL of 50 mg/kg/day. This study was considered supplemental.

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c. Studies from the open literature - dietary or intraperitoneal exposureCollins et al. (1971) studied the reproductive effects of carbaryl in Mongolian gerbils (Merionesunguiculatus), comparing the results to a parallel study in Osborne-Mendel rats (data notsummarized here). Gerbils were fed diets containing carbaryl (99% pure) at 0, 2000, 4000, 6000or 10,000 ppm for 100 days starting at weaning. Forty control pairs were then mated, along with30 pairs for each dose group except for the high dose, which had 18. Non-survival of high doseF2b males made it necessary to reuse F2a males to generate the F3b generation. Litters wereobserved on the day of birth to determine the number of stillborn and liveborn young and forabnormalities. They were observed again on post partum day (ppd) 4 for number and conditionof the living pups. At weaning, F3a and F3b animals from the 0 and 6000 ppm groups werepreserved for histopathology.

Impairment of fertility was evident at the high dose, becoming certain with the F2generation. Statistically significant effects at other doses were less clearly related to exposure 9.

Fertility index at increasing doses, 1st mating-2nd mating, F1 generation: 95%-89%, 83%-84%,77%*-78%, 93%-79%, 83%-64%; F2 generation: 98%-100%, 97%-93%, 93%-93%, 90%-93%, 60%*-33%**; F3 generation: 100%-98%, 87%*-81%*, 93%-89%, 95%-81%*, 50%*-0%**; *p<0.05,**p<0.01.

Mean litter size, 1st mating-2nd mating, F1 generation: 4.90-4.26, 4.27-3.60, 3.97-4.13, 4.50-3.61,4.00-3.00; F2 generation: 5.70-5.23, 5.07-4.55, 4.47*-4.79, 4.50*-5.00, 3.20*-1.33*; F3 generation: 5.68-5.27, 4.43**-4.12**, 4.93-4.61, 5.14-4.21, 3.00-0.00*; *p<0.05, **p<0.01.

Mean liveborn per female mated, 1st mating-2nd mating, F1 generation: 4.67-4.13, 4.13-3.56, 3.67-4.00, 3.80-3.36, 3.06*-2.57; F2 generation: 5.60-5.10, 4.80-4.24, 3.90**-4.50, 4.03**-4.56, 3.00**-1.33**; F3 generation: 5.60-4.27, 4.20**-4.00*, 4.60*-4.39, 4.59-3.86**, 3.00-0.00**; *p<0.05,**p<0.01.

Mean survivors to day 4 per female mated, 1st mating-2nd mating, F1 generation: 3.55-3.32, 2.37-2.68, 2.20*-2.57, 2.23*-1.93*, 0.94**-1.00**; F2 generation: 4.70-4364, 3.57*-3.31*, 2.30**-2.46**,1.97**-2.30**, 1.40**-0.67**; F3 generation: 4.52-4.47, 3.03**-3.12*, 2.33**-2.50**, 2.82**-1.81**,1.50*-0.00**; *p<0.05, **p<0.01.

Mean survivors to day 21 per female mated, 1st mating-2nd mating, F1 generation: 3.30-3.16, 2.33-2.48, 2.07-2.43, 2.10-1.86, 0.56**-0.79**; F2 generation: 4.17-4.26, 3.43-3.17, 2.17**-2.18**, 1.60**-2.15**, 1.20**-0.67**; F3 generation: 4.02-3.95, 2.73**-2.77*, 2.07**-2.36**, 2.27**-1.76**, 1.50-0.00**; *p<0.05, **p<0.01.

Mean male weanling weight in grams, 1st mating-2nd mating, F1 generation: 15.1-14.5, 15.4-15.6,11.1*-14.0, 13.1*-13.6, 13.2**-13.4; F2 generation: 14.1-13.9, 13.6-13.3, 13.6-14.0, 13.0-13.3, 11.8**-NSW [no survivors to weaning]; F3 generation: 14.2-14.4, 13.4-14.4, 12.9**-13.4, 13.3-12.9, 11.5**-NSW; *p<0.05, **p<0.01.

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The mean number of pups per litter was convincingly decreased at the high dose, thoughstatistically significant decrements were also noted at 2000, 4000 and 6000 ppm. The meannumber of liveborn pups per litter exhibited similar behavior, i.e., significant, but not clearlydose-responsive, effects at dose levels as low as 2000 ppm and clear effects at 10,000 ppm. The mean number of survivors to day 4 was reduced at all dose levels. The mean number ofsurvivors to day 21 was probably also reduced at doses as low as 2000 ppm. Weanling weightswere decreased at 4000 ppm and up. This was particularly true for males.

Adult body weights and food consumption were not monitored in this study, precludingcalculation of internal doses. Nonetheless, using 100 g as the average adult gerbil weight and 8g/day as the average food consumption (Harkness and Wagner, 1983), the high dose of 10,000ppm would correspond to an internal dose of approximately 800 mg/kg/day, with the lowerdoses proportionally smaller. Though clear dose responsiveness was not evident in somecases, a reproductive LOEL was set at 2000 ppm (~160 mg/kg/day) based on statisticallysignificant decreases in the mean numbers of liveborn pups per litter, the mean number ofsurvivors to days 4 and 21, and the mean weanling weights at that dose and above. However,the internal dose calculations assume that these relatively high dietary carbaryl levels had noeffect on food consumption or body weight. As this assumption could not be proven, theresultant internal doses, as well as the calculated internal dose LOEL, should be viewed withcaution and only in support of more authoritative data. While the authors were persuaded thatparallel rat data indicated that rats may have been less sensitive than gerbils, this was notaltogether clear from inspection of that data. At any rate, in view of the very high doses and theunusual rat strain, the rat data were not summarized for this document.

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Jordan et al. (1975) subjected male Balb mice to daily injections of Karbatox 75 (carbaryl; puritynot stated) for 10 and 20 days (propoxur was also tested, though those data will not bediscussed here). The number of treated mice was not reported. The dose was 20 mg/kg/day.

No histopathologic effects were seen in testicular, liver or kidney sections, nor werethere karyotypic changes in spleen or testicular tissues. However, there were statisticallysignificant increases in nuclear volume in neurosecretory cells of the hypothalamus (nucleussupraopticus: 362.57 µ3 in controls, 408.61 µ3 in treated animals; nucleus paraventricularis:312.18 µ3 in controls, 359.34 µ3 in treated animals) and in the number of Gomori stained-positive glial cells per 0.076 mm2 of the nucleus habenulae (controls: 5.75, treated animals:6.88). The authors speculated that the increase in Gomori stained cells was a responsedesigned to protect the brain from xenobiotic-induced toxicity. No speculation was offered toexplain the cell volume changes, but it might be inferred that they may lead to further endocrineor reproductive effects.

This summary was included because it attempted to measure potential testicularhistopathology, which is relevant to the discussion of possible carbaryl effects, and because itprovided evidence for possible effects on neurosecretory cells in the brain.

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Osterloh et al. (1983) examined the testicular effects in C57BL mice of intraperitoneal exposureto 10 separate pesticides, including carbaryl (99.8% purity). Four of these compounds wereknown testicular toxins (dibromochloropropane, dinitrobutylphenol, Ordram and Benomyl) andthree were known mutagens (dibromochloropropane, chlorbenzilate and atrazine). Carbaryl wasadministered on 5 consecutive days to 4 male mice/dose at 0 (corn oil alone),12, 25, 50, 100,200, 400 and 800 mg/kg/day. The mice were sacrificed on day 35, and the morphology of 200sperm per mouse assessed by oil immersion microscopy. In addition, testicular weights andtotal epididymal sperm counts were determined. Methyl methanesulfonate served as thepositive control substance.

Carbaryl had no effect on any of the testicular parameters measured, even at levelsabove the LD50 for this compound (LD50 = 108-650 mg/kg; Cranmer [1986]). Similarly, none ofthe other compounds elicited testicular toxicity. The authors speculated that this assay may berelatively insensitive to the effects of recognized testicular toxins, either because the mouse wasresistant to testicular effects of these particular xenobiotics or the assay was improperly timedvis a vis the spermatogenic cycle. Though the authors don’t mention it, the intraperitoneal routemay also not be optimal for testicular toxicity. In any case, the apparent negativity ofintraperitoneally administered carbaryl on sperm morphologic parameters in this study shouldbe viewed with caution, particularly in the context of positive observations from other studies.

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Table III-12. NOEL and LOEL values in laboratory animal studies on the reproductive toxicity ofcarbaryl

Species,strain

Study type &exposureregimen

Effects at LOELNOEL(mg/kg/day)

LOEL(mg/kg/day) Reference

CD rat 2-gen. repro.,dietary

parental: \ wt. gains

repro.: no effect at HDT a

pup: [ F2 mortality

parental: 5-6mg/kg/dayrepro.: >92-136mg/kg/daypup: 75 ppm b

parental: 21-36mg/kg/dayrepro.: >92-136mg/kg/daypup: 300 ppm b

AcceptableTyl et al.(2001)

Rat (strainnotidentified)

12-month oralgavage

\ sperm motility, effects onhypophyseal & thyroidfunction, and adrenal & thyroidhistopath.

<7 mg/kg/day(LDT) a

7 mg/kg/day(LDT) a

SupplementalShtenberg &Rybakova(1968)

Wistar rat(% only)

90-day oralgavage

changes in testicular enzymelevels, and sperm / testicularhistopath.

<50 mg/kg/day(LDT)1

50 mg/kg/day(LDT)1

SupplementalPant et al.(1995)

Druckreyrat (%only)

60-day oralgavage

damage to the % reproductivesystem

25 mg/kg/day 50 mg/kg/day SupplementalPant et al.(1996)

Mongoliangerbil

100-day dietary repro.: \ # liveborn pups, \ #survivors (days 4-21), \weanling weights

repro.: <2000ppm (~160mg/kg/day) (LDT) a, c

repro.: 2000ppm (~160mg/kg/day)(LDT) 1,3

SupplementalCollins et al.(1971)

a HDT, high dose tested; LDT, low dose testedb This value is expressed as a dietary concentration because it was not possible to determine actualcarbaryl intake in the pups.c The internal dose levels in the gerbil study were calculated using published values for average bodyweight and food consumption in that species (Harkness and Wagner, 1983). Use of these default bodyweight and food consumption values was based on the unproven assumption that they were unaffected bythe carbaryl intake.

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G. DEVELOPMENTAL TOXICITY

1. OverviewDevelopmental toxicity studies in rats, rabbits and mice did not indicate specific problemsstemming from carbaryl exposures. There were, however, indications from two studies in theopen literature that carbaryl is a developmental toxin in beagle dogs. The extent to whichdevelopmental toxicity occurs in the absence of maternal toxicity and the relevance of the dog inthe context of a human health risk assessment are considered in later sections of thisassessment.

The results of the developmental toxicity studies are summarized in Table III-13.

2. Laboratory animal studiesa. Rats - gavage

Pregnant, sperm positive, CD rats, 25/dose group, received carbaryl (99.0% purity) by gavageat 0 (0.5% methylcellulose 400; 10 ml/kg), 1, 4 or 30 mg/kg/day, on gestation days (gd) 6-20(Repetto-Larsay [1998]). Maternal body weights were determined on gd 0 and 6-21. Clinicalobservations were performed daily. The dams were sacrificed on gd 21, after which graviduterine weights, number of corpora lutea and number and status of implantations weredetermined. Live fetuses were removed and examined and their placental weights measured.Approximately half of the live fetuses were fixed and dissected for internal examination. Theremaining half were eviscerated, fixed and stained for skeletal examination.

No deaths occurred in any dose group. At 30 mg/kg/day, 18/25 dams registered at leastone occurrence of increased salivation within 20 minutes of administration, disappearing byabout 1 hr. This observation was made primarily between gd 14 and 20, though in two animals itwas noted as early as gd 7. Statistically significant decrements in maternal body weight gainwere noted at 30 mg/kg/day over the entire gestation period (weight gains at ascending doses,gd 6-21: 132.76, 137.76, 132.48, 96.88** g; **p<0.01), with marked effects noted within one dayof the commencement of dosing (weight gains, gd 6-7: 3.16, 4.76, 3.04, -3.12** g; **p<0.01).These effects were accompanied, and probably caused by, decreases in food consumption atthe high dose (food consumption at ascending doses, gd 6-9: 27.74, 28.04, 28.49, 22.90**g/day; **p<0.01). Clear treatment effects were not evident for the following parameters:maternal necropsies, corpora lutea, implantations, preimplantation loss, post implantation loss,resorptions, dead fetuses and gender ratio. Mean fetal body weights were reduced in astatistically significant manner at the high dose for both males and females (mean male fetusweights: 5.56, 5.56, 5.46, 5.10** g; mean female fetus weights: 5.24, 5.20, 5.25, 4.87** g). Thenumber of live fetuses classified as runts (defined as those with body weight #75% of controlmeans) rose at the high dose, with a statistically significant effect in evidence when the datawere expressed on a per litter basis (incidence of runts, fetal data: 0/377, 3/389, 3/377, 8/389;litter data: 0/25, 2/25, 3/25, 6/25*; *p<0.05). Incomplete or absent ossification of the 7th cervicalcentrum, incomplete ossification of the 5th sternebra and non ossification of the 1st metacarpaewere increased at 30 mg/kg/day. These were considered to reflect the lower fetal weights at thehigh dose, which in turn may have resulted from lower maternal weight gains at that dose.

The maternal NOEL was set at 4 mg/kg/day, based on clinical signs and suppressedbody weight gains at 30 mg/kg/day. The developmental NOEL was also 4 mg/kg/day, based onlower fetal body weights and ossification delays at 30 mg/kg/day. This study was acceptable byFIFRA guideline standards.

b. Rabbits and mice - gavage

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Timed-pregnant New Zealand White rabbits were exposed to carbaryl (99% purity) by gavageon gestation days (gd) 6-29 (Tyl et al. [1999]). There were 22 animals/dose. Doses were 0(0.5% aqueous methylcellulose; 2 ml/kg), 5, 50 or 150 mg/kg/day. Dose selection was based ona rangefinding study using 100 mg/kg/day as the high dose. In that study, plasma ChE wasinhibited to 41% of control and RBC ChE to 80.1% of control (not statistically significant) at 10mg/kg/day.

Clinical observations were made twice daily during the dosing period. Maternal bodyweights were determined every three days between gd 0 and 27, and again on gd 29 and 30.Food consumption w as monitored throughout. Blood was drawn for plasma and RBC ChEdeterminations on gd 25. Terminal sacrifices were carried out on gd 30, 1-1.5 days beforeparturition, followed by maternal necropsy and determination of litter and fetal status.

There were no deaths attributed to carbaryl exposure, though one doe each at 0 and 5mg/kg/day and two does at 50 mg/kg/day died on days 29 and 30. There were also no maternalclinical signs attributed to exposure. Maternal weight gains were statistically significantlysuppressed at 150 mg/kg/day for gd 6-9 (at ascending doses: 69.4, 62.4, 31.3, -74.8** g;**p<0.01), 29-30 and 6-30 (529.1, 524.4, 453.3, 325.9** g). Weight gains also tended to be lessat 50 mg/kg/day, though statistical significance was not achieved. Food consumption was eithernot notably affected or was, at 50 mg/kg/day, increased (food consumption, gd 6-29: 41.6, 43.6,49.8**, 40.0 g/kg/day). Both plasma and RBC ChE, measured on gd 25, were suppressed at 50and 150 mg/kg/day by statistically significant margins (plasma ChE: 211, 183, 114**, 67**mU/ml; RBC ChE: 1083, 1019, 679**, 796** mU/ml).

Uterine examinations revealed no treatment effects on numbers of corpora lutea,implantation sites, pre- or postimplantation loss, number of live fetuses/litter or gender ratio.However, the mean fetal body weights were statistically suppressed at the high dose (%: 52.69,51.29, 50.48, 47.44* g; &: 50.40, 49.76, 50.42, 45.34** g). While the number of fetuses withskeletal malformations showed a small increase at the high dose (0/153, 0/174, 0/137, 2/171),both observations were due to fused sternebrae and occurred in a single litter. This could not beclearly ascribed to carbaryl exposure.

The maternal NOEL was set at 5 mg/kg/day, based on suppression of RBC and plasmaChEs at 50 and 150 mg/kg/day. The developmental NOEL was set at 50 mg/kg/day, based onreduced fetal body weights observed at 150 mg/kg/day. This study was considered to beacceptable by FIFRA guidelines.

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Murray et al. (1979) examined the teratogenic potential of carbaryl (99.0% purity) in NewZealand White rabbits and CF-1 mice after oral gavage (both species) or dietary (mice only)exposure. Doses were designed to approximate MTDs determined in preliminary studies.Pregnant rabbits were treated by gavage with 0 (1 ml cottonseed oil/kg), 150 or 200 mg/kg/daycarbaryl on gestation days (gd) 6-18. Pregnant mice were either treated by gavage with 0 (5 mlcottonseed oil/kg), 100 or 150 mg/kg/day on gd 6-15, or through the diet to 0 or 2830 ppm on gd4-5 and to 0 or 5660 ppm (~1166 mg/kg/day) on gd 6-15. There were 13-20 rabbits/dose (twoseparate groups were run as concurrent controls with each dose) and 23-44 mice/dose(includes both exposure routes). The animals were observed daily during gestation for clinicalsigns, with maternal body weights established at predetermined intervals. Conventionalobservations were conducted for pregnancy status and fetal condition (external, soft tissue andskeletal observations).

Rabbits, gavage. Diarrhea was observed at 200 mg/kg/day only (quantitative data notprovided). One death occurred among the controls and one among the 150 mg/kg/day group.These were not attributed to carbaryl exposure. Both controls and dosed animals lost weight

10 Omphalocele is defined as a “protrusion, at birth, of part of the intestine through a large defectin the abdominal wall at the umbilicus, the proturding bowel being covered only by a thin transparentmembrane composed of amnion and peritoneum” (Dorland’s Illustrated Medical Dictionary, 26th edition,page 921). It is considered to be an external malformation.

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over the gestation day 6-11 period, though the latter decrements were statistically greater thanthe controls (controls vs. 150 mg/kg/day, gestation days 6-11: -0.03±0.09 kg vs. -0.15±0.10* kg;controls vs. 200 mg/kg/day, -0.03±0.07 kg vs. -0.31±0.10* kg; *p<0.05).

There was no effect on the mean number of live fetuses per litter, though there was amarginal, non-statistically significant increase in resorptions at both doses (resorptions per litter,control vs. 150 mg/kg/day, 0.8±1.2 vs. 1.3±2.8; control vs. 200 mg/kg/day, 0.5±1.1 vs. 1.5±1.9).

Fetal body weights were reduced at both doses, though only the lower dose achievedstatistical significance (control vs. 150 mg/kg/day, 37.9±5.4 g vs. 34.0±3.4* g; control vs. 200mg/kg/day, 39.2±4.2 g vs. 36.7±3.8 g). Fetuses also were slightly smaller in size, though not bystatistically significant margins (fetal crown-rump length, control vs. 150 mg/kg/day, 93.5±5.9mm vs. 91.1±3.6 mm; control vs. 200 mg/kg/day, 96.3±4.1 mm vs. 93.8±3.6 mm).Omphalocele10 occurred at statistically higher rates among the 200 mg/kg/day animals thanamong controls (control vs. 150 mg/kg/day, total fetuses [total litters], 0/113 [0/14] vs. 1/149[1/17]; control vs. 200 mg/kg/day, 0/113 [0/13] vs. 6/82 [4/12]*). The four dams that gave birth topups exhibiting this malformation sustained the greatest gestation day 6-11 mean weight loss(440 g). Single cases of omphalocele, hemivertebrae and conjoined nostrils with missing nasalseptum were observed at 150 mg/kg/day, but statistical significance was not achieved.

The developmental LOEL in rabbits was 150 mg/kg/day based on the increase inomphalocele at 150 and 200 mg/kg/day. The single incidence of this malformation at 150mg/kg/day was considered to be exposure-related because of the extremely low incidenceamong historical controls (laboratory historical controls revealed only 2 cases among 338litters). The maternal LOEL in rabbits was 150 mg/kg/day based on statistically significantweight gain deficits at 150 and 200 mg/kg/day. Neither developmental nor maternal NOELswere determined. As noted in the report (p. 87), “the individual dams which had offspring withomphalocele were among those which demonstrated the greatest degree of maternal toxicity”(though the individual data required to verify this statement were not provided in the report). Asimilar statement was not made with respect to the single incidence at 150 mg/kg/day. It couldnot therefore be stated with assurance that omphalocele occurred only in the presence ofmaternal toxicity.

Mice, gavage and diet. Maternal toxicity was noted at the 150 mg/kg/day gavage dose.There were 10/37* deaths, compared to 0/41 among controls and 1/23 among animals gavagedat 100 mg/kg/day (*p<0.05). In addition, salivation, ataxia and lethargy were noted at 150mg/kg/day. No clinical signs were noted among controls or low dose animals. Animals exposedto 5660 ppm carbaryl in the feed (~1166 mg/kg/day) exhibited neither deaths nor clinical signs.Mean dam weight gains, gd 6-9, were statistically reduced in the high dose gavage animals(weight gains at 0, 100 and 150 mg/kg/day: 2±1, 2±2 and 0±2* g). Animals exposed through thediet did not show a significant weight gain decrement between gd 6-9 (weight gains at 0 and5660 ppm: 2±1 and 1±2 g), but did between gd 10-15 (11±4 and 7±4* g). There was astatistically significant increase at the high gavage dose in the number of pregnancies detectedby sodium sulfide stain only, a procedure that was conducted only on those animals thatappeared not to be pregnant (0/12, 1/2 and 4/7*). Implantations per dam, live fetuses per litter,resorptions per litter and sex ratio were not affected under any treatment regimen. However,fetal body weights were significantly reduced in the group exposed through the diet to 5660 ppm

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carbaryl (1.02±0.12 vs. 0.80±0.14* g), as was the fetal crown-rump length (24.1±1.3 mm vs.22.2±1.8* g). Skull and sternebral ossification delays were also reported at that dose, thoughquantitative data were not provided. The fetal growth and ossification effects in the dietarilyexposed animals probably reflected the reduced maternal weight gains during the gd 10-15period. The dams exposed by gavage did not exhibit such effects, though it is noted that thegavage doses were much lower than the dietary dose. No statistically significant increase inmalformations was noted by either exposure route, though two incidences of hemivertebra andfused ribs were noted in the dietarily exposed group.

The developmental NOEL in mice treated by oral gavage was >150 mg/kg/day (nodevelopmental adverse effects were noted). The maternal NOEL in gavaged mice was 100mg/kg/day based on deaths, cholinergic signs and weight gain deficits (gd 6-9) at 150mg/kg/day.

A developmental NOEL was not established for mice treated through the diet. Thedevelopmental LOEL for dietarily exposed mice was 5660 ppm (1166 mg/kg/day), based ondecreased fetal body weights, decreased fetal crown-rump lengths and ossification delays. Amaternal NOEL was also not established for these animals. The maternal LOEL was 5660 ppm(1166 mg/kg/day), based on decreased maternal body weight gains.

c. Dogs - dietarySmalley et al. (1968) (with additional discussion and data in Cranmer [1986]) exposed beagledogs to dietary carbaryl (99.9% pure) at 0, 3.125, 6.25, 12.5, 25 or 50 mg/kg/day. Each dog wasfed once daily with 35 g of feed per kg body weight. Females were mated in estrus with onemale on day 1 and a second male on day 3. Dosing began between days 3 and 6 after mating,continuing until the end of gestation (avg. gestation length, 62 days). The number of femalesper dose group varied between 16 (concurrent controls) and 8 (high dose). Clinical observationswere made on a daily basis. Body weights were recorded weekly for dams and pups.Necropsies were performed at weaning (8 wk). Cholinesterase activities were not measured.

There were neither clinical signs nor discernable effects on maternal body weightsduring gestation. Dystocia, defined in this study as a “pattern” of difficult births (delayed deliveryaccompanied by restlessness, anorexia, fever, and the presence of a green-black, foul-smellingvaginal discharge; also, placental separation and atonic uterine musculature were evident insome cases), was seen in dosed animals, though a dose-response was not apparent: Thenumber of dams showing dystocia / number bred was, at increasing doses: 0/16, 3/10, 3/10,5/18, 3/9, 3/8. One female from each of three dose groups (6.25, 25 and 50 mg/kg/day) showedevidence of conception but all of the resultant fetuses died. According to the report (p. 396),“The uteri in these cases showed four to six evenly spaced round prominences of the same sizein each animal. On incision, it was found that the masses were encapsulated, closely adherentto the uterine mucosa, and composed of yellow-green caseous material with foci ofcalcification.” The number of implantations per litter and the number of resorptions per litterwere reported only for the dosed animals (i.e., not for the controls). Implantations per litter were,at increasing doses: nr (not reported), 8.7, 9.6, 6.1, 6.5 and 6.0. Resorptions per litter were: nr,3.1, 4.7, 1.2, 2.7 and 2.5. It appeared, therefore, that carbaryl exposure at 12.5 mg/kg/day andabove may have caused decreased implantation, though without control data it was not possibleto state this with assurance. Conception was notably reduced at the high dose only: 81%, 70%,80%, 89%, 78%, 37%. No pups were born alive at the high dose: 81%, 66%, 62%, 38%, 60%,0%.

While the mean pup weights were similar among dose groups at birth, the rate of pupweight gain in the combined dose groups was less than the control group. For example,inspection of the pup weight graph indicates about a 33% disparity between controls and

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combined dose groups by week 8 (weaning). Unfortunately, since the mean pup weights ateach dose were not provided, it was impossible to determine the minimum dose required forsuch weight gain effects. All pups exhibited normal avid nursing behavior, though dosed pupscried more and sustained higher mortality.

The percent of pups weaned decreased with dose (73%, 60%, 50%, 23%, 39%, 0%),though the cause of death was not determined. The number of litters containing pups withabnormalities appeared to rise with treatment above 3.125 mg/kg (0/13, 0/7, 1/7, 3/16, 3/6, 1/2;historical controls: 3/313), though the small numbers of animals, particularly at the high dose,precluded a definitive statement of dose responsiveness. The abnormalities included“abdominal-thoracic fissures with varying degrees of intestinal agenesis and displacement,varying degrees of brachygnathia, ecaudate pups [i.e., without a tail], failure of skeletalformation, failure of liver development, and superfluous phalanges” (p. 392).

Thus serious developmental and teratogenic effects of carbaryl were evident in thisstudy. The absence of maternal clinical signs distinct from the dystocia noted at parturition wasnotable. Limitations on numbers of animals, common for a dog study, curtailed the ability todocument dose responsiveness and statistical significance.

The maternal LOEL was set at the low dose of 3.125 mg/kg/day based on the dystocianoted at all dose levels. Consequently, a maternal NOEL was not set, despite the fact that nomaternal clinical signs outside of dystocia were observed. Implantations were suppressed atand above 12.5 mg/kg/day, an observation which may indicate either general maternal toxicityor a more specific degeneration of the uterine environment making it unfavorable toimplantation. It should be noted that, unlike the FIFRA-compliant rat or rabbit studies, wherefetal exposure commences after implantation and is limited to the period of organogenesis,dosing in the present study commenced on gestation day 3 and continued throughout gestationand weaning.

The developmental NOEL was 3.125 mg/kg/day based on teratogenic abnormalities inpups detected at both the litter and individual animal levels at doses as low as 6.25 mg/kg/day.There was insufficient data on pup weight gain decrements to include that parameter as aNOEL determinant. This study is considered to be supplemental.

^^^^^^^^^^^^^^^^^^^^

Immings et al. (1969) studied the effects of dietary carbaryl (purity, 99.84%) in pregnant beaglesand their offspring. Four untreated males acted as sires. Dosing commenced on gestation day1, continuing through pup weaning at 6 weeks of age. Twelve females/group were dosed at 0, 2,5 and 12.5 mg/kg/day. Body weights were determined weekly. Each animal was presented with200 grams of dosed feed mixed with 45 grams of canned beef. Food consumption was notrecorded and the report does not state whether or not the whole presentation was consumedevery day; consequently, there was uncertainty about the actual delivered doses. Gestationlength, numbers of viable and stillborn pups and mean litter weights were determined at birth,followed by culling of the litters to six. Mean pup weight was determined at weaning. Pupautopsies were performed only when considered necessary by the veterinarian.

Table III-13 summarizes the maternal and pup data. Of the mated females, 9/12, 7/12,9/12 and 9/12 became pregnant. One female in each carbaryl-exposed group died. The deathreported at 2 mg/kg/day was an animal killed in extremis on day 48 due to poor health andconvulsions. The mid and high dose deaths occurred at parturition; signs were not reported forthose animals. The pattern of pregnancies and maternal deaths did not clearly implicatecarbaryl. While the presence of convulsions in the low dose death might be construed ascholinergic, the absence of this sign at higher doses may indicate that it was not related tocarbaryl exposure. The time of occurrence (day 48) for a sign that is more likely to be acute in

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nature, in addition to the absence of other cholinergic signs, also supported a non-carbaryl-dependent etiology. Effects of carbaryl on maternal body weight were not apparent.

Carbaryl exposure may have increased the incidence of stillbirths at the top two doses(p<0.01). There was even a hint of a similar effect at the low dose (p>0.05). The increasedstillbirth incidence was present at both the fetal and litter levels. It should be noted, however,that all the pups from the two animals dying during parturition were stillborn (high dose female#5030 Y 8 pups; mid dose female #5575 Y 4 pups), as were all 5 pups from one mid dosefemale (#5202) that aborted on day 41. If these were excluded from the data, the incidence ofstillborn pups at increasing doses was 1/45, 3/33, 7/37* and 6/49 (*p<0.05). The litter incidencewas 1/9, 3/7, 4/7 and 4/8. While these adjusted data were weaker, they remained consistentwith a carbaryl-mediated effect, even at the low dose.

Also indicated was an increased number of pup deaths commencing 24 hours after birthin treated groups. The report noted that 18 of these deaths occurred in litters arising frommatings that occurred during a specific 2-month time period, arguing that the increase may havebeen due to an infectious agent (evidence for this could not be deciphered from the report).Since a greater proportion of these particular matings occurred in animals destined to be treatedwith carbaryl (i.e., only one control litter and one low dose litter were among these matings,compared to 4 mid dose and 4 high dose litters), the investigators felt that the increase amongtreatment groups constituted a “statistical quirk”. The pup mortality ratios between 24 hours and6 weeks which exclude these affected litters appear to bear this out. However, removing theseanimals from consideration is regarded as speculative, as it remains possible that the deathswere related to carbaryl exposure regardless of the presence or absence of infection. It shouldalso be noted that a litter effect did not manifest in these data.

Abnormalities were detected in the pups at the mid and high doses. These includedumbilical hernia, cleft palate, fat-like mass in the heart, intussuception of the ileum into thecolon, extravasation of blood in the myocardium and unilateral microphthalmia. The reportstates that, with one exception, all of these signs occurred in litters produced from the allegedlyproblematic 2-month mating period. However, this cannot be viewed as certain. Finally, two of 8pups from a mid-dose litter showed incomplete ossification of the 13th rib, though no otherskeletal abnormalities were noted.

A developmental LOEL of 2 mg/kg/day was set for this study based on the non-statistically significant increase in stillbirths at that dose. Because it was the low dose, adevelopmental NOEL was not determined. On a per-litter basis, statistical significance wasachieved only at the mid dose, though the incidences at the low and high doses weresuggestive of an effect. Also increasing at the mid and high doses were number of viable pupdeaths commencing 24 hours after birth and the occurrence of visceral abnormalities among thepups. Carbaryl-related maternal effects were not reported in this study. Consequently, thematernal LOEL was >12.5 mg/kg/day. Because fetal effects occurred at lower doses thanmaternal effects, carbaryl may be a developmental toxin in the dog. Nonetheless, the problemsnoted in the study should be recognized.

The primary deficiencies in this study included a lack of dose analysis, no necropsiesperformed on the mothers, mother’s ages not reported, and the high dose may not have beensufficient. This study is considered to be supplemental.

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Table III-13. Effect of subchronic exposure to dietary carbaryl on pregnant beagle dogs andtheir offspring; Immings et al. (1969)

Dose (mg/kg/day)

Effects 0 2 5 12.5

Maternal

Mated females 12 12 12 12

Number pregnant 9 7 9 9

Maternal deaths 0 1a 1 b 1 b

Offspring

Total birthsMean births / litter

455.0

334.7

465.1

576.3

Live births Live births / litter

444.9

304.3

303.3

434.8

Stillbirths / total pups[# available litters]

1/45 (2%)[1/9] (11%)

3/33 (9%)[3/7] (43%)

16/46** (35%)[6/9]* (67%)

14/57** (25%)[5/9] (56%)

Deaths (0-24 hr) / total pups[# available litters]

1/44 (2%)[1/9] (11%)

0/30 (0%)[0/7] (0%)

0/30 (0%)[0/7 c] (0%)

1/43 (2%)[1/8 d] (13%)

Deaths (24-48 hr) / total pups[# available litters]

0/43 (0%)[0/9] (0%)

2/30 (7%)[1/7] (14%)

2/30 (7%)[2/73] (29%)

4/42 (10%)[3/84] (38%)

Deaths (48 hr - 6 wk weaning) / total pups[# available litters]

5/43 (12%)[4/9] (44%)

10/28* (36%)[3/7] (43%)

9/28* (32%)[5/73] (71%)

12/38* (32%)[5/84] (63%)

Deaths (24 hr - 6 wk weaning) / total pups[# available litters]

5/43 (12%)[4/9] (44%)

12/30** (40%)[4/7] (57%)

11/30* (37%)[5/73] (71%)

16/42** (38%)[6/84] (75%)

Removing affected litters: e

Deaths (24 hr - 6 wk weaning) / total pups[# available litters]

5/39 (13%)[4/8] (50%)

10/25* (40%)[3/6] (50%)

7/15* (47%)[3/3] (100%)

4/18 (22%)[2/4] (50%)

Total pup mortality[# available litters]

7/45 (16%)[6/9] (67%)

15/33** (45%)[7/7] (100%)

27/46** (59%)[9/9] (100%)

31/57** (54%)[9/9] (100%)

a This low-dose mother was killed in extremis on day 48 with convulsions and in poor general health.b The mid and high-dose maternal deaths occurred at parturition on days 54 and 61, respectively.c Two mid-dose litters experienced total litter loss at birth. Consequently, the number of available litterswas reduced from 9 to 7 for all deaths of fetuses that were born alive.d One high-dose litter experienced total litter loss at birth. Consequently, the number of available litterswas reduced from 9 to 8 for all deaths of fetuses that were born alive.e Litters born from matings during a certain 2-month span are removed from consideration here due to theauthors’ suspicion of illness (see text).

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Table III-14. NOEL and LOEL values for studies on the developmental toxicity of carbaryl

Species,strain

Study type &exposure regimen Effects at LOEL

NOEL(mg/kg/day)

LOEL(mg/kg/day) Reference

CD rat oral gavage,gestation days 6-20

maternal: clinical signs(salivation) & suppressed body wt.gains

dvp.: \ fetal body wts. &ossification delays

maternal: 4mg/kg/day

dvp.: 4 mg/kg/day

maternal: 30mg/kg/day

dvp.: 30 mg/kg/day

Acceptable c

Repetto-Larsay (1998)

NZWrabbit

oral gavage,gestation days 6-29

maternal: \ RBC and plasma ChE

dvp.: \ fetal body wts.

maternal: 5mg/kg/day

dvp.: 50 mg/kg/day

maternal: 50mg/kg/day

dvp.: 150mg/kg/day

AcceptableTyl et al.(1999)

NZWrabbit

oral gavage,gestation days 6-18

maternal: \ body wt. gain

dvp.: omphalocele

maternal: <150mg/kg/day (LDT) a

dvp.: <150mg/kg/day (LDT)1

maternal: 150mg/kg/day (LDT)1

dvp.: 150mg/kg/day (LDT)1

Supplemental c

Murray et al.(1979)

CF-1 mouse oral gavage,gestation days 6-15

maternal: deaths, \ body wt. gain,clinical signs

dvp.: no adverse effects noted

maternal: 100mg/kg/day

dvp.: >150mg/kg/day (HDT)1

maternal: 150mg/kg/day (HDT)1

dvp.: >150mg/kg/day (HDT)1

SupplementalMurray et al.(1979)

CF-1 mouse dietary, gestationdays 4-15

maternal: \ body wt. gain

dvp.: \ fetal body wts., \ fetalcrown-rump length, ossificationdelays

maternal: <1166 mg/kg/day (HDT &LDT)1

dvp.: <1166mg/kg/day (HDT &LDT)1

maternal: 1166 mg/kg/day (HDT &LDT)1

dvp.: 1166mg/kg/day (HDT &LDT)1

SupplementalMurray et al.(1979)

Beagle dog dietary, gestationday 3 - parturition(~gd 62) b

maternal: dystocia

dvp.: teratogenic abnormalities(abdominal-thoracic fissures,brachygnathia, ecaudate pups,failure of skeletal formation,failure of liver development,superfluous phalanges

maternal: <3.125mg/kg/day

dvp.: 3.125mg/kg/day

maternal: 3.125mg/kg/day

dvp.: 6.25mg/kg/day

SupplementalSmalley et al.(1968)

Beagle dog dietary, gestationday 1 - weaning(pup age 6 wk)

maternal: no adverse effects noted

dvp.: [ stillbirths

maternal: >12.5mg/kg/day (HDT)

dvp.: <2 mg/kg/day(LDT)

maternal: >12.5mg/kg/day (HDT)

dvp.: 2 mg/kg/day(LDT)

SupplementalImmings et al.(1969)

a HDT, high dose tested; LDT, low dose testedb Dietary exposure probably continued through weaning, 8 weeks post partum, though the report was notexplicit on this point.c The designation "Acceptable" indicates that the study was successfully completed according to FIFRAguidelines. "Supplemental" indicates that the study was not conducted according to FIFRA guidelines;however, such studies were reviewed and considered to contribute to the general genotoxic picture of thechemical.

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H. DEVELOPMENTAL NEUROTOXICITY

Robinson and Broxup (1997) exposed 32 pregnant CD rats/dose to carbaryl (99.1% purity) bydaily gavage from gestation day (gd) 6 through post partum day (ppd) 10 inclusive. Doses were0 (aqueous 0.5% carboxymethylcellulose / 0.1% Tween 80, 10 ml/kg/day), 0.1, 1 or 10mg/kg/day. Twenty-six animals from each group were examined for developmental neurotoxicityand 6 were examined for cholinesterase activity (plasma, whole blood and brain). The F1generation, consisting of 3 males and 3 females, was weaned at day 21.

F0 animals were checked twice daily for mortality and toxic signs. Body weights weredetermined on gd 0, 6, 9, 12, 15, 18 and 20, and again on ppd 0, 4, 7, 11, 13 and 21. Modifiedfunctional observational batteries were performed 0.5-2 hr post dose on all days in which bodyweights were determined, excepting ppd 0. Gross pathology was done on ppd 21-23.

Dams destined for cholinesterase determinations were weighed on ppd 10. Bloodsamples were obtained predose on gd 6, and 1 hr post dose (i.e., at the time of peak effect) ongd 6, 15 and 20, and on ppd 4 and 10 for blood ChE assays. Brains were removed, weighedand analyzed for ChE on ppd 10.

Pups were weighed on ppd 0, 4, 7, 11, 13, 17 and 21. Litters were culled to 4/sex/litteron ppd 4. Tooth eruption was assessed from ppd 7 and eye opening from ppd 12. 1/sex/litterwere subjected to neuropathology or brain weight determinations on ppd 11. Motor activity testswere performed in figure-8 mazes on 1/sex/litter for 1 hr on ppd 13, 17 and 21. Litters wereweaned on ppd 21 to provide the F1 adult generation.

F1 adults were weighed weekly and examined twice daily for mortality and clinical signs.For females, vaginal opening was assessed from ppd 26 until development of this character.For males, preputial separation was assessed from ppd 34 until development of this character.Motor activity was assessed on ppd 60. Auditory startle habituation was measured on ppd 22 &60. Passive avoidance tests were conducted on ppd 23 and 24. “E” water maize testing wasconducted between ppd 60 and 65. Animals not selected for the F1 generation were sacrificed,necropsied and brain weights determined at weaning. Brains from 6 high dose and 6 controlpups/sex were subjected to histopathology and brain morphometry. At approximately 10 weeksof age, at least 12/sex/group underwent perfusion fixation. Neuropathology was conducted on agiven fraction of these animals. Neural morphometry was conducted on a further 6 F1 adultsfrom the control and high doses.

Results, F0 animals (only females tested). There were neither treatment-relateddeaths nor signs detected in twice daily examinations. Reduced weight gains were noted at 10mg/kg/day for the gd 6-9 period: 6.6, 7.7, 7.2 and 0.5** grams (**p<0.01) at ascending doses.FOB testing at 10 mg/kg/day revealed an increased incidence in dams with pinpoint pupils on alloccasions during the dosing period (p<0.05-0.005), as well as in dams with slight tremors orslight ataxic gait on many occasions (Table III-15a). Slight hypotonic gait also increased at 10mg/kg/day (statistically significant at gd 18, p<0.01), and possibly increased at 1 mg/kg/day(statistically significant at gd 12, p<0.05). However, the overall gait data were not sufficientlyrobust at 1 mg/kg to make a definitive determination on this point. A graphic representation ofthe slight hypotonic gait data appears below in Figure 2. The FOB data were also suggestive ofan increase in slight tremors at 1 and 10 mg/kg/day, though the incidence numbers, particularlyat 1 mg/kg, were low.

RBC ChE activity was suppressed by statistically significant margins at the high dose ongd 20 and ppd 10 (Table III-15b). Suppression was noted on other measurement days as well,but didn’t achieve statistical significance. Brain ChE was statistically suppressed at the highdose on ppd 10, the only measurement day. The same trend was apparent for plasma ChE,though statistical significance was not indicated at any dose. Gross pathology did not reveal an

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effect of carbaryl. The number of dead pups increased at the high dose (mean number / litter atascending doses: 0.1, 0.1, 0.1, 0.3). Because it fell within the historical control range (0.0-0.9),the authors did not ascribe toxicologic significance to this effect. However, an effect of carbarylon pup death could not be ruled out.

F1 pups. There were no unambiguous effects of carbaryl in the F1 pups, though meanmotor activity counts for day 13 females were elevated at 10 mg/kg/day at each of the sixmeasurement intervals (mean counts for all intervals at ascending doses: 67.1±75.6, 75.1±63.3,52.1±55.8, 111.0±114.8). Though these failed to achieve statistical significance, theirconsistency at all measurement intervals suggested the possibility of a treatment effect. Evenso, it is noted that wide variability in the individual data led to very large standard deviations,decreasing the robustness of this particular data set. These data were not considered sufficientto establish a LOEL value. Some brain morphometric measurements showed differencesbetween control and high dose animals in both F1 pups sacrificed on ppd 11 and F1 adultssacrificed on ppd 70. However, as these results were inconsistent in degree and direction (i.e.,smaller or larger morphometric distances), they were also difficult to attribute unambiguously tocarbaryl exposure.

F1 adults. There were no clear effects of carbaryl in the F1 adults.The LOEL determination for maternal effects hinged on whether or not the incidence of

FOB signs was sufficiently robust at 1 mg/kg to support values of regulatory significance. At 10mg/kg, very clear body weight gain decrements, RBC and brain cholinesterase inhibition, andFOB signs (pinpoint pupils, slight tremors, slight ataxic gait and slight hypotonic gait) werepresent. These endpoints, in the absence of signs at 1 mg/kg, would set the maternal NOEL at1 mg/kg. However, there was weaker evidence from the FOB data for effects - slight hypotonicgait in particular, but also slight tremors - at 1 mg/kg. Benchmark dose analysis of the slighthypotonic gait data produced an LED10 of 0.25 mg/kg (see section IV.1.a.). Both 1 mg/kg and0.25 mg/kg were used to gauge the potential acute risk from exposure to carbaryl. The NOELfor developmental effects was set at the high dose of 10 mg/kg/day, with no LOEL establishedfor developmental endpoints. It was nonetheless recognized that elevated motor activity countsat 10 mg/kg/day in day 13 F1 females may have resulted from carbaryl exposure. This study was deemed acceptable according to FIFRA standards.

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Table III-15a. Selected functional observational battery observations in F0 females during theperiod of dosing with carbaryl (gd 6 - ppd 10), F0 females (Robinson and Broxup [1997])

Carbaryl dose (mg/kg/day)

Control 0.1 1.0 10.0

Slight hypotonic gait gd 6 a, c

gd 9 c gd 12 c gd 15 c gd 18 c gd 20 c ppd 4 a

ppd 7 ppd 11 ppd 13 ppd 21

6/23 (26.1) b

7/26 (26.9)5/26 (19.2)7/25 (28.0)5/25 (20.0)9/25 (36.0)3/21 (14.3)5/21 (23.8)8/21 (38.1)4/21 (19.0)1/21 (4.8)

7/26 (26.9)2/26 (7.7)

5/26 (19.2)11/26 (42.3)10/26 (38.5)5/26 (19.2)3/23 (13.0)6/23 (26.1)5/23 (21.7)5/23 (21.7)1/23 (4.3)

7/26 (26.9)10/26 (38.5)

13/26 (50.0)*14/26 (53.8)11/26 (42.3)11/26 (42.3)7/24 (29.2)9/24 (37.5)6/24 (25.0)3/24 (12.5)3/24 (12.5)

11/23 (47.8)11/26 (42.3)11/26 (42.3)10/26 (38.5)

15/26 (57.7)**13/26 (50.0)4/24 (16.7)8/24 (33.3)7/24 (29.2)6/24 (25.0)6/24 (25.0)

Slight ataxic gait gd 6 gd 9 gd 12 gd 15 gd 18 gd 20 ppd 4 ppd 7 ppd 11 ppd 13 ppd 21

0/23 (0)0/26 (0)0/26 (0)0/25 (0)0/25 (0)0/25 (0)0/21 (0)0/21 (0)0/21 (0)0/21 (0)0/21 (0)

0/26 (0)0/26 (0)0/26 (0)0/26 (0)0/26 (0)0/26 (0)0/23 (0)0/23 (0)0/23 (0)0/23 (0)0/23 (0)

0/26 (0)0/26 (0)0/26 (0)0/26 (0)0/26 (0)0/26 (0)0/24 (0)0/24 (0)0/24 (0)0/24 (0)0/24 (0)

2/23 (8.7)1/26 (3.8)2/26 (7.7)0/26 (0)0/26 (0)

1/26 (3.8)3/24 (12.5)

0/24 (0)0/24 (0)0/24 (0)0/24 (0)

Slight tremors gd 6 gd 9 gd 12 gd 15 gd 18 gd 20 ppd 4 ppd 7 ppd 11 ppd 13 ppd 21

1/23 (4.3)0/26 (0)0/26 (0)0/25 (0)0/25 (0)0/25 (0)0/21 (0)0/21 (0)0/21 (0)0/21 (0)0/21 (0)

2/26 (7.7)0/26 (0)

1/26 (3.8)0/26 (0)0/26 (0)0/26 (0)0/23 (0)0/23 (0)0/23 (0)0/23 (0)0/23 (0)

2/26 (7.7)2/26 (7.7)0/26 (0)0/26 (0)

1/26 (3.8)0/26 (0)

1/24 (4.2)0/24 (0)0/24 (0)0/24 (0)0/24 (0)

5/23 (21.7)4/26 (15.4)3/26 (11.5)

0/26 (0)4/26 (15.4)

8/26 (30.8)***1/24 (4.2)0/24 (0)0/24 (0)0/24 (0)0/24 (0)

Pinpoint pupils gd 6 gd 9 gd 12 gd 15 gd 18 gd 20 ppd 4 ppd 7 ppd 11 ppd 13 ppd 21

0/23 (0)0/26 (0)

1/26 (3.8)2/25 (8.0)1/25 (4.0)1/25 (4.0)0/21 (0)0/21 (0)0/21 (0)0/21 (0)0/21 (0)

1/26 (3.8)0/26 (0)0/26 (0)

3/26 (11.5)1/26 (3.8)0/26 (0)

1/23 (4.3)0/23 (0)

1/23 (4.3)0/23 (0)0/23 (0)

0/26 (0)0/26 (0)0/26 (0)0/26 (0)

2/26 (7.7)1/26 (3.8)0/24 (0)

3/24 (12.5)0/24 (0)0/24 (0)0/24 (0)

9/23 (39.1)***4/26 (15.4)7/26 (26.9)*

12/26 (46.2)***13/26 (50.0)***16/26 (61.5)***

6/24 (25.0)*12/24 (50.0)***

0/24 (0)0/24 (0)0/24 (0)

111

Moderate dilation ofpupils gd 6 gd 9 gd 12 gd 15 gd 18 gd 20 ppd 4 ppd 7 ppd 11 ppd 13 ppd 21

2/23 (9)4/26 (15)2/26 (8)2/25 (8)3/25 (12)7/25 (28)0/21 (0)3/21 (14)2/21 (10)1/21 (5)1/21 (5)

7/26 (27)5/26 (19)0/26 (0) q4/26 (15)4/26 (15)

10/26 (38)1/23 (4)6/21 (29)4/23 (17)2/23 (9)3/23 (13)

5/26 (19)2/26 (8)2/26 (8)2/26 (8)4/26 (15)5/26 (19)1/24 (4)4/24 (17)4/24 (17)2/24 (8)3/24 (13)

1/23 (4)1/26 (4) q

0/26 (0) qq0/26 (0) qq

1/26 (4)0/26 (0) qq

0/24 (0)5/24 (21)8/24 (33)2/24 (8)1/24 (4)

Signs (per animal basis) d

gd 6 gd 9 gd 12 gd 15 gd 18 gd 20 ppd 4 ppd 7 ppd 11 ppd 13 ppd 21

6/23 (26.1)7/26 (26.9)6/26 (23.1)8/25 (32.0)6/25 (24.0)9/25 (36.0)3/21 (14.3)6/21 (28.6)8.21 (38.1)4/21 (19.0)1/21 (4.8)

7/26 (26.9)2/26 (7.7)

5/26 (19.2)12/26 (46.2)10/26 (38.5)5/26 (19.2)3/23 (13.0)7/23 (30.4)5/23 (21.7)5/23 (21.7)3/23 (13.0)

7/26 (26.9)10/26 (38.5)

13/26 (50.0)*14/26 (53.8)12/26 (46.2)10/26 (38.5)7/24 (29.2)12/24 (50.0)6/24 (25.0)3/24 (12.5)3/24 (12.5)

16/23 (69.6)***12/26 (46.2)

14/26 (53.8)*12/26 (46.2)

18/26 (69.2)**18/26 (69.2)*11/24 (45.8)*17/24 (70.8)**

7/24 (29.2)6/24 (25.0)6/24 (25.0)

* Fisher exact test, p<0.05; **Fisher exact test, p<0.01; ***Fisher exact test, p<0.005. These statisticaltests were executed by the risk assessor. q Fisher exact test, p>0.95; qq Fisher exact test, p>0.99. These statistical tests were executed by the riskassessor.a Abbreviations: gd, gestation day; ppd, post partum dayb Numbers in parentheses are the incidence rates expressed in percentages.c Shirley's non-parametric test using incidences between gd 6 and gd 20 indicates the presence ofstatistically significant responses at 1 and 10 mg/kg/day for slight hypotonic gait.d Includes animals in which more than one sign was noted. Only positive signs were considered (i.e., thedecline in incidence of moderate dilation of pupils was not included).

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Table III-15b. RBC, plasma and brain cholinesterase activities in F0 female CD rats during theperiod of dosing with carbaryl (gd 6 - ppd 10) (Robinson and Broxup [1997])

Carbaryl dose (mg/dg/day)

Control 0.1 1.0 10.0

RBC ChE (U/L) gd 6 a gd 15 gd 20 ppd 4 a ppd 10

988.3±204.711127.0±172.191173.7±86.84844.3±170.02894.3±14.84

990.0±129.77 (100.2)1245.8±195.29 (110.5)1171.7±91.94 (99.8)869.3±181.60 (103.0)938.0±91.64 (104.9)

913.5±272.84 (92.4)1203.5±249.12 (106.8)1251.2±179.24 (106.6)943.0±113.56 (111.7)933.0±127.11 (104.3)

800.0±194.49 (80.9)1064.3±325.46 (94.4)845.4±93.90** (72.0)752.2±127.43 (89.1)643.2±41.25** (71.9)

Plasma ChE (U/L) gd 6 a gd 15 gd 20 ppd 4 a ppd 10

844.8±287.11981.7±335.65

1049.0±129.73729.0±140.22560.0±103.26

964.4±209.26 (114.2)1097.5±207.81 (111.8)1134.2±212.91 (108.1)696.7±190.06 (95.6)491.2±66.55 (87.7)

902.0±333.78 (106.8)1149.5±419.31 (117.1)1124.2±291.13 (107.2)702.0±234.21 (96.3)539.2±164.74 (96.3)

697.8±240.35 (82.6)975.0±314.37 (99.3)644.0±134.76 (61.4)498.2±66.44 (68.3)359.0±81.32 (64.1)

Brain ChE (U/g) ppd 10 5.9±0.04 6.2±0.22 (104.7) 5.8±0.16 (97.9) 3.4±0.58** (58.2)

a Abbreviations: gd, gestation day; ppd, post partum dayParenthetical values represent percent of concurrent controls.

11 Superimposition of data points resulted in less than six identifiable points / dose in this figure.

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Figure 2. Scatter plot depicting the fraction of animals exhibiting slight hypotonic gait on each ofsix examination days11; the dotted line is a representation of the average response at the dosestested.

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I. TOXICITY OF THE CARBARYL DEGRADATES AND METABOLITES

1. 1-NaphtholHuman exposure to 1-naphthol likely occurs through the metabolism of carbaryl or naphthalene.Exposure is also plausible through the use of this chemical in microscopy, as a coupler incosmetic hair dyes, or in the manufacture of dyes and intermediates (CIR Expert Panel [1989]).Poole and Buckley (1989), citing a 1980 EPA TSCA review, stated that, "In humans a largeingestion of naphthol can cause nephritis, vomiting, circulatory collapse, anaemia, convulsionsand death, and if sufficient quantities are absorbed through the skin, injury to the cornea andlens of the eye and also the kidney may occur". Reviews from two cosmetics industry panels(the Cosmetics Indgredient Review Panel [CIR Expert Panel [1989] and the ScientificCommittee on Cosmetic Products and Non-Food Products Intended for Consumers [SCCNFP,2001]) summarized the limited data available on the mammalian toxicity of 1-naphthol, usinglargely the same database of studies. As indicated by the citations below, much of the followinginformation is derived from those reviews, with specific study references to be found withinthem. In addition, short TSCA (Toxic Substances Control Act) summaries were available. Thesesummaries are quoted below along with their references.

Pharmacokinetics. Male mice receiving 1-naphthol by oral gavage (corn oil vehicle) showed a24-hr elimination of 68% in the urine and 13% in the feces; the major metabolites were 1-naphthyl glucuronide and 1-naphthyl sulfate. Intraperitoneal injection of Sprague-Dawley ratswith 7.5 µm/kg 1-naphthol (2-methoxyethanol vehicle) resulted in 83.5% urinary elimination /16.5% tissue retention at 4 hr and 91.0% urinary elimination / 1.4% fecal elimination / 7.6%tissue retention at 48 hr. In a separate study, 1-naphthol labeled with 14C at the 1-carbon wasadministered intraperitoneally to cats, pigs and rats at a dose of 25 mg/kg; at 24 hr, 91% of theradioactivity had been excreted in the urine of cats (98% sulfate conjugate,1.4% glucuronideconjugate), 81% in the pig (32% sulfate, 66% glucuronide) and 59% in the rat (53% sulfate,47% glucuronide). Incubation of radiolabeled 1-naphthol with human blood for 24 hr resulted inthe binding of 97.6% to plasma (92.8% of that in albumin, 3.6% in heavy lipoprotein and 3.6% inlight lipoprotein fractions). In the same study, injection of mice with 1-naphthol, followed after 10min by sacrifice and blood centrifuation showed 20-30% in the RBC fraction; the plasma fractionshowed 43% associated with albumin and 43% with lipoproteins. A very limited study usingthree male volunteers determined that 1-naphthol contained in an ointment was rapidlyabsorbed. (CIR Expert Panel, 1989)

Acute oral toxicity. LD50, rats: 2300 (1700-3300) mg/kg - study #1; 2590 mg/kg - study #2. (SCCNFP, 2001)

Poole and Buckley (1989), in the acute dosing section of a larger study (subchronic sectionbelow), treated two CD1 mice/sex/dose with 1-naphthol by gavage. The doses were 0-untreatedcontrol, 0-vehicle control (vehicle: propane-1,2-diol : water, 1:1), 0.5, 1 or 2 g/kg 1-naphthol.Survivors were observed for up to 2 weeks post dose. Sacrifice was followed by post mortemexam, blood analysis (clinical chemistry and hematology), and fixation of major organs forhistolopathologic analysis.

All high dose mice were killed in extremis between 15 and 90 minutes after dosing. Theyexhibited tremors, abnormal respiration and collapse. All mid dose animals survived, exhibiting,then recovering from, subdued behavior and piloerection. Low dose animals also showed thesesigns (in addition to labored breathing); one low dose animal was killed in extremis 2 hr postdose, while the other three animals survived.

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Histopathologic changes were noted as follows. Kidney: (1) both high dose males, onelow dose male and both mid dose females exhibited "eosinophilic deposits in the lumen of thedistal tubules and collecting ducts associated with degeneration of the distal tubular epithelia"; (2) one mid dose male and both mid dose females exhibited "papillary necrosis with anassociated intravascular thrombosis"; (3) both mid dose females exhibited "marked dilatation ofboth cortical medullary tubules". Gut: (1) all but one of the mid and low dose mice exhibited"focal splitting of the squamous epithelium, which was generally associated with vascularcongestion and an acute inflammatory cell infiltration"; (2) all high dose mice, one male and onefemale mouse and one low dose male exhibited "sloughing of the superficial epithelium of theglandular mucosa... generally, this change was associated with vascular congestion and anacute inflammatory cell infiltration". There were no effects noted on hematologic or clinicalchemical parameters (though it is noted that blood was not obtained from those animalssacrificed in extremis).

An acute LOEL was set at the low dose of 0.5 g/kg, based on death and histopathologicchanges in the kidneys and gut. An acute NOEL was not determined.

This study was considered to be supplemental.

TSCA submissions: "1-Naphthol (CAS # 90-15-3) was evaluated for acute oral toxicity. The testsubstance was administered by stomach intubation to non-fasted male albino Harlan-Wistarrats. The observed LD50 was 2.38 (1.56 to 3.65) g/kg, and 1.87 (1.27 to 2.76) g/kg for youngand older adult rats, respectively. No further information was submitted.[UNION CARBIDE CORP; Temik and Other Materials Miscellaneous Single Dose Peroral andParenteral LD50 Assays and Some Joint Action Studies; 01/20/70; EPA No. FYI-OTS-0885-0443; Fiche No. OTS0000443-0]**UNREVIEWED**"

"1-Naphthol (CAS # 90-15-3) was evaluated for acute oral toxicity. The test substance wasadministered as a 50% solution in peanut oil. Rats receiving lethal doses suffered from diarrheaand died within 18 hours after treatment. Pathological examination indicated congestion andedema of the lungs; albumin in the kidney tubules; and superficial necrosis of the stomach. Theapproximate lethal dose (ALD) was calculated to be 1000 mg/kg.[Letter to USEPA Regarding the Enclosed Acute and Chronic Oral Toxicity Studies on 1-Ethoxy-4-Nitrobenzene with Attachments (Sanitized); 11/27/91; EPA No. 86-920000378S; Fiche No.OTS0533716]**UNREVIEWED**"

Acute dermal toxicity. TSCA submission: "1-Naphthol (CAS # 90-15-3) was evaluated foracute dermal toxicity. The test substance was administered to 5 albino rabbits at a dosage of10,000 mg/kg. No mortality and no signs of intoxication occurred. Dermal irritation consisted ofmoderate erythema and edema. Gross autopsy revealed no significant findings.[Summary Results Concerning an Acute Oral LD50, Acute Eye Irritation, Primary Skin & EyeIrritation Indexes & 28-Day Subacute Feeding Studies with Cover Sheet & Letter (Sanitized);00/00/00; EPA No. 86-920000514S; Fiche No. OTS0533803]**UNREVIEWED**"

Acute / sub-acute inhalation toxicity. Four adult dogs (splenectomized 4-8 yr prior) wereexposed for four 7-10 min periods, 4 times/day, for 4 days to 3% 1-naphthol (deodorizedkerosene vehicle). The study ran for 10 days. Other than the observation that one of the fourdogs exhibited at least a doubling in the number of reticulocytes on days 7 and 10, there wereno effects noted. (CIR Expert Panel, 1989)

Subchronic oral toxicity. "1-Naphthol orally administered to rats (20 males and 20 females)

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for 12 weeks (5 times a week) showed that the dose of 20 mg/kg b.w./day (10 ml/kg) does notrepresent a toxic cumulative dose." (SCCNFP, 2001)

Poole and Buckley (1989), in the subchronic dosing section of their study (for the acute section,see above), treated five CD1 mice/sex/group with daily gavage doses for 30 consecutive days.The doses were 0-untreated control, 0-vehicle control (vehicle: propane-1,2-diol : water, 1:1),50, 100 and 200 mg/kg. Sacrifice on day 31 was followed by post mortem exam, blood analysis(clinical chemistry and hematology), and fixation of major organs for histolopathologic analysis.

Two high dose males were sacrificed in extremis on study days 4 and 20, respectively.Both of these animals "showed evidence of focal mucosal erosion of the gandular stomach withsome evidence of healing and peeling of the mucosa of the forestomach. The lesions werebelieved to have contributed to the poor clinical condition of the mice." A third high dose malealso showed focal erosion of the glandular stomach, but survived. All females survivedtreatment, with none of the high dose animals showing gastric lesions.

While clear dose-related effects were not observed for clincal chemical parameters,hematologic analysis did reveal an apparent dose-related rise in white blood cell counts amongfemales (at increasing doses the WBC counts in females were 7.64-untreated control, 6.24-treated control, 9.45, 10.5 and 12.2 x 109 / L) , though this was less clear in males (4.88-untreated control, 4.48-treated control, 7.13, 8.10, and 6.35 x 109 / L). The report claims thatthese increases were within the historical control range for the laboratory.

Body weight gains were suppressed at all doses, though a dose relation was notevident. Thus weight gains in control males and females was 4.9±2.3 g and 4.4±1.7 g,respectively, while in the combined dose groups they were 1.7±1.4 and 1.6±1.4 g.

A subchronic LOEL was set at the low dose 50 mg/kg, based on weight gain decrementsand possible effects on female white blood cell counts. A subchronic NOEL was not determined.

This study was considered to be supplemental.

Subchronic dermal toxicity. "A formulation containing 1-naphthol (0.5%), mixed 1:1 withhydrogen peroxide, topically applied [1 hr/day] for 13 weeks (twice weekly) on abraded andintact skin of rabbit showed no evident toxic effect." (SCCNFP [2001])

Chronic toxicity and carcinogenicity dermal route. "One oxidative formulation (7403, mixed1:1 with 6% hydrogen peroxide) containing 0.5% 1-naphthol was tested on Swiss Webster miceby [once weekly] dermal application (0.05 ml/cm2 x 21 months). No adverse effects werereported." (SCCNFP, 2001). In addition, there was no evidence for carcinogenicity. (CIR ExpertPanel [1989])

Irritation (skin). "The compound was applied to intact and abraded skin of rabbit at doses of2.5% (0.5% aqueous gum tragacanth solution with 0.05% sodium sulphite, pH=7); it resulted notirritating [sic] after reading at 24 and 72 hours (primary irritation index = 0). No signs of irritancywere noted." (SCCNFP [2001])

Skin irritation was tested in guinea pigs with three lots of 1-naphthol applied as a 3%suspension, 0.5 ml per animal, to a shaved area of 1 in2. Minor irritation was detected with twolots at 24 hr, but not at 48 or 72 hr. (CIR Expert Panel [1989])

"When applied to the skin of rabbits for 24 h, 500 mg of 1-naphthol caused severe irritation.Moderate irritation of the skin was observed when rabbits were treated with 550 mg 1-naphtholin open patches." (CIR Expert Panel [1989])

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TSCA submission: "1-Naphthol (CAS # 90-15-3) was evaluated for primary dermal irritation.The test substance was administered at a dosage of 500 mg to the intact and abraded skin of 6albino rabbits. Moderate to severe erythema and edema was noted after 72 hours (irritationscore of 7.09/8.00).[Summary Results Concerning an Acute Oral LD50, Acute Eye Irritation, Primary Skin & EyeIrritation Indexes & 28-Day Subacute Feeding Studies with Cover Sheet & Letter (Sanitized);00/00/00; EPA No. 86-920000514S; Fiche No. OTS0533803]**UNREVIEWED**"

Irritation (mucous membranes). "The compound was instilled into one eye of 12 rabbits atconcentrations of 0.5% - 1.5% - 2.0% - 2.5% w/v (0.5% in aqueous gum tragacanth with 0.05%sodium sulphite, 3 animals/dose) and the eyes were washed out 10 sec after treatment. Theresults (ocular reaction evaluated at 1 h and 1-2-3-4-7 days) showed the minimum irritant level,between 1.5% and 2.0%: positive reactions were observed in 2/3 of the rabbits at 2.0% w/v and1/3 of the rabbits at 2.5% w/v." (SCCNFP [2001])

"When applied to the surface of rabbit eyes, 1-naphthol caused damage to the cornealepithelium at a grade of 9 on a scale of 1-10. 1-Naphthol, 1 mg, when instilled into the eyes ofrabbits, caused severe irritation." (CIR Expert Panel [1989])

TSCA submission: "1-Naphthol (CAS # 90-15-3) was evaluated for primary eye irritation. Thetest substance was administered at a dosage of 100 mg to 6 albino rabbits. Slight to moderateeffects of the cornea, iris, and conjunctivae were noted (irritation score of 61.7/110).[Summary Results Concerning an Acute Oral LD50, Acute Eye Irritation, Primary Skin & EyeIrritation Indexes & 28-Day Subacute Feeding Studies with Cover Sheet & Letter (Sanitized);00/00/00; EPA No. 86-920000514S; Fiche No. OTS0533803]**UNREVIEWED**"

Sensitization. "1-Naphthol (3% in water with 2.0% Natrosol, 2% Tween 80, 0.05% Sodiumsulphite and 10% isopropanole) showed no allergic reaction in guinea pig by open epicutaneousmethod." (SCCNFP [2001])

"Sensitization was induced in 20 guinea pigs by simultaneously intradermal injections in theshoulder region of 0.1 ml of Freund's Complete Adjuvant (FCA), 0.1 ml 1-naphthol (0.1% inwater) and a 1:1 mixture of test compound and 0.05 ml Adjuvant at day 0. The test compoundwas dermally applied (0.1% in water) 7 days later, under occlusion, on the injection site for 48hours. 14 days later the guinea pigs were challenged by dermal application on the flank with0.1% and 0.05% of 1-naphthol (aqueous solutions), under occlusion for 24 hours. The resultsevaluated after 24 and 48 hours of challenge showed that 1-naphthol was not a sensitiser inguinea pigs. Result: The sensitisation capacity was not properly assessed because the choiceof concentration, for induction and challenge, may have been too low." (SCCNFP [2001])

Teratogenicity / embryotoxicity. "A formulation containing 1-naphthol (0.5%, 1:1 withhydrogen peroxide) was topically applied [2 ml/kg/day or 10 mg/kg/day] to the shaven skin ofrats on day 1-4-7-10-13-16-19 of gestation. Only a significant reduction of the mean number ofcorpora lutea was observed between treated and two control groups (12.85 vs. 15.35 or 13.55).There was no evidence of any teratogenic or other adverse effect in the developing embryo /foetus." (SCCNFP [2001])

"25 female Sprague-Dawley Albino rats/group; Dosage 20, 40, 80 mg/kg bw. 1-Naphthol dailyday 6 to 15 of gestation; Blank control (solvent); positive control 15 mg/kg/ vit. A; Acknowledged

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methodologies. Results: At any dose level no treatment related effects. No maternal norembryonic or foetal signs attributable to the test substance. In conclusion no maternal orembryo-toxicity, no incidence of embryo-lethality or growth retarding effects; no teratogenicity upto the highest tested dose of 80 mg/kg." (SCCNFP [2001])

Mutagenicity / genotoxicity. The following studies were summarized by the CIR Expert Panel,1989:

‚ Nine Salmonella / Ames studies using various strains were negative. Onestudy was positive in strain TA1538, with a maximal effect at 500 mg/plate in thepresence of S9 microsomes (negative in three other strains). One study waspositive in five strains in the absense of S9 microsomes.

‚ Two mutagenicity / DNA repair assays in various E. Coli strains, ±S9microsomes, were negative.

‚ A Rec assay in B. subtilis, was positive in the absence of S9 and negativein the presence of S9.

‚ Micronucleus assays in rat and mouse bone marrow were negative.

‚ Examination of lymphocytes from men and women who had dyed theirhair every 3-6 weeks for 11 months showed no effects on sister chromatidexchanges or chromosomal aberrations.

‚ Rat bone marrow cells were negative for chromosome aberrations.

‚ The mouse lymphoma cell line L5178Y did not show gene mutationsupon in vitro exposure.

‚ Unscheduled DNA synthesis did not occur in rat hepatocytes in responseto 1-naphthol exposure.

‚ An in vivo multigenerational Basc test in Drosophila was negative.

In the context of a discussion of genotoxicity, it should also be recalled that 1-naphthol, likecarbaryl, induced an aberrant form of mitosis called c-mitosis that may reflect effects on mitoticspindle formation (Soderpalm-Berndes and Onfelt [1988] - see discussion above, sectionIII.E.3.).

In vitro cytotoxicity. 1-Naphthol was cytotoxic in several in vitro systems, including sarcomaBP 8 cells, chick embryo trachea organ cultures, rat primary hepatocytes, HeLa cells andhuman skin fibroblasts. (CIR Expert Panel [1989])

2. MethylamineMethylamine is produced upon hydrolytic breakdown of carbaryl, which occurs under alkalineconditions. This compound is known for its irritant properties to eyes, nose and throat upon briefexposures to 20 - 100 ppm. Severe methylamine exposure may lead to pulmonary edema. Theoral LD50 in rats is 100 - 200 mg/kg (Proctor et al, 1988). Shelby et al. (1987) demonstrated

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positivity in the L5178Y mutagenicity assay. Gavage exposure of mice to 122 mg/kgmethylamine for 5 days produced a statistically significant 27% drop in white blood cell counts(Keil et al. [1996]).

Regulatory limits. The OSHA PEL for methylamine is 10 ppm. The ACGIH TLV (TWA) is 5 ppm,with a STEL of 15 ppm.

12 Post gestational exposures were not included in the analysis because the animals appeared lesssensitive following the end of pregnancy.

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IV. RISK ASSESSMENT

A. HAZARD IDENTIFICATION

1. Non-oncogenic effectsa. Acute oral toxicity

The most sensitive acute (or short-term) toxicologic endpoints for carbaryl were identified in thegavage developmental neurotoxicity study of Robinson and Broxup (1997). Because theputative effects at 1 mg/kg were not definitive, two acute regulatory values were derived fromthis study.

(1) A NOEL of 1 mg/kg, based largely on clear, statistically significant FOBsigns (slight hypotonic gait, slight ataxic gait, slight tremors and pinpoint pupils)observed at the high dose of 10 mg/kg, was established. Since those signs werepresent on the first day of dosing (gd 6), they were unmistakably acute in nature,though effects seen at any time during the FOB testing were arguably acute (seethe discussion of carbaryl disposition in mammalian systems below). In addition,a statistically significant decrease in bodyweight gain at 10 mg/kg/day was notedat the first post dosing measurement on gd 9. This also represented an acute ornear-acute effect, as the measurement was made only three days after the startof dosing. It is not known if the lowered cholinesterase activities observed at 10mg/kg (statistically significant in RBCs at gd 20 and ppd 10, and in brain at ppd10, the only day the brain enzyme was assayed) were acute or required severaldaily exposures. However, it is noted that RBC cholinesterase activities weresuppressed by almost 20% (p>0.05) even at the first post dosing measurementon gd 6.

(2) A "lower bound on the effective dose at the 10% level" (LED10) of 0.25 mg/kgwas obtained through benchmark dose (BMD) modeling applied to the slighthypotonic gait incidence data gathered during gestation. While these data werenot as robust as the FOB and body weight data at 10 mg/kg used to support the1 mg/kg NOEL designated in #1 above, they nonetheless represented a plausiblereflection of cholinergic effects even at the mid dose of 1 mg/kg.

BMD is a method by which a threshold, or benchmark dose, is established for atoxicologic endpoint using mathematically fitted curves to model the data overmost or all of the dose range. The benchmark response level for slight hypotonicgait was set to 10%, a value generally used by DPR to characterize mildtoxicologic signs. Because of carbaryl’s propensity for clearance from the ratsystem in less than 24 hours (Struble, 1994) and the relatively rapiddecarbamylation reaction (t0.5 = 40 min [cf., Cranmer, 1985]), all of the FOB testsconducted during the gestation period were considered to represent separate,but equivalent, acute scenarios 12. Consequently, the gestational data sets werecombined to generate a normalized mean incidence rate, as noted in Table IV-1.

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Use of mean data in the BMD analysis was preferable to use of data from anyday in isolation, as it minimized the random fluctuations noted in single day tests.

Initial attempts to model the full mean data set using the algorithms available inUSEPA’s BMD application version 1.3 were inappropriate because theyunderestimated responsiveness between 0.1 and 1 mg/kg, the dose-responseregion of primary interest. This was due to the pronounced leveling of the curveabove 1 mg/kg (Figure 2), which led to underestimation of the slope between 0.1and 1 mg/kg and resultant LED10 values higher than a putative effect level at 1mg/kg. However, deletion of the top dose resulted in an appropriate curve fitusing the probit algorithm (Appendix I). As noted, the resultant LED10 was 0.25mg/kg (ED10 = 0.47 mg/kg).

Three acute toxicity studies from the same laboratory established low dose acute LOELs at 10mg/kg in the rat, similar to the level at which there were overt clinical signs, body weight gaindeficits and suppressed cholinesterase activities in the study of Robinson and Broxup (1997).These were considered supportive both of the 1 mg/kg NOEL and the 0.25 mg/kg LED10.

(1) The acute gavage study of Brooks and Broxup (1995b) demonstrated clearinhibition of all cholinesterases (including brain cholinesterase) at this dose. Forexample, at 0.5 hr post dose, brain cholinesterase activities at 10, 50 and 125mg/kg were 46%, 23% and 18% of concurrent controls, respectively, whilefemale activities were 54%, 24% and 22% of controls. Benchmark dose analysisusing the Hill algorithm of the male data yielded LED10 (ED10) values of 0.61(0.94) mg/kg. Marked inhibition was also seen for plasma cholinesterase in thisstudy, though somewhat less inhibition occurred with RBC cholinesterase.Recovery was substantial by 24 hr.

(2) Brooks and Broxup (1995c) demonstrated a low dose rat acute gavage LOELof 10 mg/kg based on cholinesterase inhibition at 1 hr post dose in a studydesigned to examine the time course of inhibition. In particular, braincholinesterase was inhibited to 57%-73% of control activities at that time.

(3) A study of neurobehavioral and neuromorphologic effects of carbaryl afteracute gavage exposure established a low dose LOEL of 10 mg/kg (Brooks et al.,1995). This was based on a statistically significant reduction in motor activitycounts in both sexes over a 60-minute period in both sexes on the day of dosing.

In a study from a separate laboratory, Moser (2007) demonstrated dose-dependent, statisticallysignificant brain ChE inhibition in pnd11 rats at gavage doses as low as the lowest tested doseof 3 mg/kg. This resulted in a LED10 (ED10) determination of 1.14 (1.46) mg/kg using benchmarkdose methodology - essentially the same as the critical acute NOEL of 1 mg/kg and reasonablyclose to the LED10 of 0.25 mg/kg.

Support for the critical acute NOEL and LED10 designations also came from the rat 50-dayneurotoxicity study (Desi et al., 1974). Changes in maze performance, including faster goalattainment with fewer errors, were evident soon after the commencement of dietary exposure at10 and 20 mg/kg/day carbaryl, the only doses tested. These early changes were probably acutein nature. They were followed some weeks later by other changes, including slower goal

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attainment and more frequent errors, which probably represented responses to subchronicexposures.

Two older dog developmental toxicity studies from the open literature indicated additionaleffects at a similar dose range (Smalley et al., 1968; Immings et al., 1969). While these studiesinvolved multiple dosing regimes, the possibility that the some of the effects were due to asingle dose could not be discounted. These studies are discussed below in section IV.1.A.c.

Support for these regulatory values was also forthcoming in the acute inhalation toxicity study ofWeinberg (2008), which established an LED10 of 5.5 mg/m3 by BMD analysis from the results ofa single 3-hr exposure. This was based on inhibition of brain cholinesterase activity at a lowdose of 10 mg/m3 (1.2 mg/kg, calculated using the default breathing rate of 0.96 m3/kg) infemales. The LED10 (ED10) was equivalent to an internal dose of 0.66 (1.59) mg/kg, abouthalfway between the critical acute NOEL of 1 mg/kg and the LED10 of 0.25 mg/kg.

Table IV-1. Incidence of slight hypotonic gait during gestation in female CD rats, including mean valuesnormalized to 26 animals (Robinson and Broxup, 1997)

Carbaryl dose (mg/kg/day)

Control 0.1 1.0 10.0

Slight hypotonic gait gd 6 a

gd 9 gd 12 gd 15 gd 18 gd 20

6/23 (26.1) b

7/26 (26.9)5/26 (19.2)7/25 (28.0)5/25 (20.0)9/25 (36.0)

7/26 (26.9)2/26 (7.7)

5/26 (19.2)11/26 (42.3)10/26 (38.5)5/26 (19.2)

7/26 (26.9)10/26 (38.5)

13/26 (50.0)*14/26 (53.8)11/26 (42.3)11/26 (42.3)

11/23 (47.8)11/26 (42.3)11/26 (42.3)10/26 (38.5)

15/26 (57.7)**13/26 (50.0)

Slight hypotonic gait (mean) 6.8/26 (26.2) 6.7/27 (25.8) 11.0/26 (42.3) 12/1/26 (46.5)* Fisher exact test, p<0.05; **Fisher exact test, p<0.01. These statistical tests were executed by the risk assessor.a Abbreviation: gd, gestation day.b Numbers in parentheses are the incidence rates expressed in percentages.

b. Chronic oral toxicityThe critical chronic oral LOEL was based on inhibition of brain cholinesterase activity at the lowdose of 3.4 mg/kg/day (actually, 3.7 mg/kg/day in females and 3.4 mg/kg/day in males) in the 1-yr dog dietary study (Hamada [1987]). The brain cholinesterase data, which evidencedstatistically significant 20% inhibition in females at 3.7 mg/kg/day compared to controls (14%non-statistically significant inhibition in males at 3.4 mg/kg/day; however, it was the latter dosethat was used to determine the LOEL), was collected after 52 weeks of exposure. The RBCcholinesterase showed statistically significant inhibition at the mid and high doses (11.0 / 11.2and 33.8 / 34.4 mg/kg/day, respectively) at all treatment intervals (weeks 5, 13, 26 and 52),while non-statistically significant inhibition was detected at the low dose (up to 14% in males atweek 13 and 13% in females at week 5, the first measurement). Plasma cholinesterase activiteswere statistically suppressed in females at all doses for weeks 5, 13 and 26 (up to 23% at thelow dose). Statistical significance in males occurred at the mid and high doses only.

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The benchmark dose approach was employed to estimate a regulatory chronic LED10 value.The Hill algorithm for continuous data generated the most appropriate curve to fit the femaleWeek 52 brain cholinesterase data. Neither the power nor polynomial algorithms generatedcomparable curves, either because AIC analysis indicated a higher value or because the overlycomplex curve shapes were considered unlikely to represent biological process. A 10%benchmark response rate was chosen in recognition of the fact that neither overt clinical signsnor histopathology were observed throughout the study, even at the high dose of ~34mg/kg/day. Appendix II provides the details for the Hill algorithm calculations.

The critical chronic LED10 for brain cholinesterase inhibition in females using the Hill algorithmwas 0.5 mg/kg/day (ED10 = 1.7 mg/kg/day). This value will be used to evaluate the non-oncogenic risks from annual (i.e., chronic) exposure to carbaryl.

c. Reproductive and developmental toxicitySeveral epidemiologic studies indicate that carbaryl may have reproductive and/ordevelopmental impacts (Wyrobek et al., 1981; Savitz et al., 1996; Meeker et al., 2004a and2004b; and Xia et al. 2005)). These are discussed below under Risk Appraisal, sectionsV.A.1.c. and V.A.1.d.. In addition, two studies in which pregnant beagle dogs were exposed tocarbaryl throughout gestation (and until weaning in one study) indicated toxicologic effects bothin the mothers and offspring. To the extent that some of these effects may have been acute(which was difficult to determine from the data as presented), they are considered supportive ofthe critical acute NOEL and LED10 based on the relatively low doses employed.

Smalley et al. (1968) observed an increase in dystocia - described as a “pattern” of difficultbirths (delayed delivery accompanied by restlessness, anorexia, fever, and the presence of agreen-black, foul-smelling vaginal discharge; also, placental separation and atonic uterinemusculature were evident in some cases) - in beagles exposed at a LOEL dose of 3.125mg/kg/day. The number of dams with dystocia / number bred at 0, 3.125, 6.25, 12.5, 25 and 50mg/kg/day were 0/16, 3/10, 3/10, 5/18, 3/9 and 3/8, respectively. In addition, the followingobservations were recorded in the Smalley study:

(1) One female from each of three dose groups (6.25, 25 and 50 mg/kg/day)sustained total fetal deaths, an observation which could not be dissociated fromcarbaryl exposure.

(2) While the mean pup weights were similar among dose groups at birth, therate of pup weight gain in the combined dose groups was less than the controlgroup by about 33%. Since pup weight data for individual dose groups was notreported, the implication was that the dose groups were not distinguishable inthis regard.

(3) The percent of pups weaned decreased with dose (73%, 60%, 50%, 23%,39%, 0%), though the cause of pup death was not reported. The association ofeffect with dose, particularly at the two lower doses (3.125 and 6.25 mg/kg/day),was not incontrovertible, as few animals were tested. But the consistency withthe other observed effects made a relationship with carbaryl exposure possible.

(4) The number of litters containing pups with abnormalities - including“abdominal-thoracic fissures with varying degrees of intestinal agenesis and

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displacement, varying degrees of brachygnathia, ecaudate pups (i.e., without atail], failure of skeletal formation, failure of liver development, and superfluousphalanges” [p. 392]) - increased with treatment above 3.125 mg/kg: 0/13, 0/7,1/7, 3/16, 3/6, 1/2; historical controls: 3/313).

A developmental LOEL of 2 mg/kg/day was set in the study of Immings et al. (1969) based on anon-statistically significant increase in stillborn beagle dogs at that dose (Table III-12). Statisticalsignificance was achieved at the mid and high doses when examined on a per-pup basis,though only at the mid dose when examined on a per-litter basis. Pup deaths, particularly thoseoccurring after 24 hr post partum, also increased at 2 mg/kg, though there was concern thatmany of these animals were conceived during a period of elevated maternal illness. An effect atthe litter level was not observed (see Table III-12 with its preceding discussion). Abnormalities -including umbilical hernia, cleft palate, fat-like mass in the heart, intussuception of the ileum intothe colon, extravasation of blood in the myocardium and unilateral microphthalmia - weredetected in the pups at the mid (5 mg/kg/day) and high doses (12.5 mg/kg/day). The co-incidence with the stillbirths and pup deaths was also attributed by the authors to maternalillness during the mating period. However, the proximity of the effective dose range in the twodog studies supported the possibility that there was an actual treatment effect.

d. GenotoxicityWith positive indications in one of five gene mutation studies, four of six chromosomalaberration studies and two of four DNA damage studies reviewed, carbaryl should be viewed asa potentially genotoxic compound. However, with the exception of one positive chomosomeaberration study in Allium cepa (onion tree), a system that was of questionable relevance tomammalian systems, all of the positive studies were performed in vitro. In general, positive invitro assays may be less relevant to the whole organism than positive in vivo results, thoughthey may provide mechanistic insights in some cases.

One study demonstrated that nitrosocarbaryl could be produced from carbaryl and nitrite underacidic in vitro conditions. A separate study showed that nitrosocarbaryl caused chromosomalaberrations in Chinese hamster fibroblasts. Finally, one study in V79 Chinese hamsterfibroblasts showed that, like carbaryl, the carbaryl metabolite %-naphthol was toxic and inducedc-mitosis, an aberrant form of mitosis that may have reflected effects on mitotic spindleformation.

2. OncogenicityOverview. Carbaryl administered through the diet was oncogenic to both mice and rats in two-year studies. Dietary exposure in mice led to hemangiosarcomas and hemangiomas in bothsexes, hepatocellular carcinomas and adenomas in females, and kidney tubular adenomas andcarcinomas in males (Table III-7c) (Hamada [1993b]). Tumors did not appear within a 6-monthtime frame in p53 knockout mice (Chuzel [1999]), suggesting that, unlike the urethane positivecontrol, carbaryl’s effects in mice may not have involved the p53 gene product. However,carbaryl increased the lung tumor yield generated by two gavage exposures in mice tobenzo[a]pyrene (Triolo et al. [1982]) and showed initiating capability in a standard mouse skininitiation-promotion assay (Shukla et al. [1992]).

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Dietary exposure in rats led to carcinomas and papillomas of the urinary bladder in both sexes,hepatocellular adenomas in females and thyroid follicular cell adenomas and carcinomas inmales (Table III-6c) (Hamada [1993a]). These were accompanied by possibly preneoplasticsigns such as cellular hypertrophy or hyperplasia, squamous metaplasia, high mitotic indexand/or atypia. In view of the positive genotoxicity tests (see previous section), it is premature toexclude genotoxicity as a possible driver in carbaryl-induced cancers in rodents, though directevidence for genotoxically-driven tumors was lacking.

Mice. In view of the tendency of male mice to form hemangiosarcomas / hemangiomas at lowerdoses than were seen for the other tumors in this species, as well as the corroborating evidencefrom comparative benchmark dose analyses of all of the relevant mouse tumor data (see below;hemangiosarcoma / hemangioma, hepatocellular adenoma / carcinoma, kidney tubule celladenoma / carcinoma), the human cancer risk was evaluated using the male mousehemangiosarcoma / hemangioma data (Hamada [1993b]). Further support for use of thisdataset came from knowledge that, while the high dose exceeded the maximum tolerated dose(MTD; this was based on early female deaths, body weight decrements and clinical signs - seesection III.D.2. for a complete discussion), the mid and low doses did not. In addition, it shouldbe recalled that carbaryl was genotoxic in several in vitro studies.

Hemangiosarcoma is defined as “a malignant tumor formed by proliferation of endothelial andfibroblastic tissue” (Dorland’s Medical Dictionary, 26th edition, p. 587). Hemangioma is definedas “a benign tumor made up of new-formed blood vessels” (Dorland’s, p. 587). The moreencompassing term angiosarcoma includes “all lesions labeled hemangiosarcoma,lymphangiosarcoma, and malignant hemangiosarcoma, since it remains uncertain whetherthese lesions are derived from blood vascular or lymphatic endothelium, or perhaps from either”(Fletcher and McKee, 1992). The latter definition is mentioned in this context because itemphasizes the unsure cellular origin of this type of tumor.

Incidences of hemangiomas and hemagiosarcomas were combined as recommended by theNational Toxicology Program (McConnell et al. [1986]). This reflects the conviction that theunderlying tumorigenic process was similar for the benign and malignant types. A dose-responsive increase was noted in males (dose response of “at risk” males: 2/66, 6/66, 10/69*and 10/68* at 0, 14.73, 145.99 and 1248.93 mg/kg/day; *p<0.05; Table III-6c). Statisticalsignificance in a Fisher pairwise test was achieved by the mid dose, though the increasebetween the control and low dose suggested that an effect was present even there. Femalesevinced a similar response, though it was manifest only at the highest dose and never attainedpairwise statistical significance (dose response of “at risk” females: 3/63, 3/70, 4/66 and 9/61 at0, 18.11, 180.86 and 1440.62 mg/kg/day [Table III-6c]). A USEPA-sponsored reanalysis of thethe pathology slides generated very similar results with respect to all tumors noted, both in themouse and rat (USEPA, 2002b). However, small changes with respect to incidence ofhemangiosarcomas alone in male mice, from 2/66, 5/66, 9/69* and 7/69 (calculated from theincidences of this lesion among interim, unscheduled and terminal sacrifices) to 1/66, 6/66*,8/69* and 8/68*, emphasized the likliehood that a tumorigenic response was present even at thelow dose in the mouse study.

Fourteen separate algorithms available in USEPA’s version 1.3.2 benchmark dose (BMD)program were compared as potential models for the male vascular tumor data. Theeffectiveness of each model was assessed by consideration of the goodness of fit (through chi-squared residuals and p-values), analysis of deviance (through the AIC numbers), and

13 Adenoma: “a benign epithelial tumor in which the cells form recognizable glandular structuresor in which the cells are clearly derived from glandular epithelium” (Dorland’s Illustrated MedicalDictionary, 26th Edition, 1985; W.B. Saunders Company; p. 31).

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inspection of the curves for biological plausibility. Because the MTD was clearly exceeded at thehigh dose, resulting in a pharmacologic or metabolic profile of little relevance to humansexposed to low doses, it was excluded from the BMD analysis.

The quantal linear model emerged as the most appropriate for this dataset (see Appendix III forthe full computer read-out of the male data). The resultant potency value for male mice, definedas the slope of the dose-risk relation, was 1.45x10-3 mg/kg/day-1 at the 95% upper bound ondose (i.e., the LED) and 7.2x10-4 mg/kg/day-1 at the maximum likelihood estimate (i.e., the ED).The LED / ED ratio was 2.01. The uncertainties inherent in this derivation of the male slopevalue are discussed in the Risk Appraisal section (V.A.2.).

In order to use the potency value to estimate risk to human populations, the mouse internaldoses were converted to equivalent human doses and the human potency values calculated.Extrapolation of the mouse doses to humans was done by multiplying those doses by aninterspecies scaling factor, using the ratio of animal-to-human bodyweight to the 1/4 power (USEPA [1992]): The mean wk. 53 male body weight was 38.4±2.2 g. Accordingly, the scalingfactor was:

(BWtA / BWtH)0.25 = (0.0384 kg / 70 kg)0.25 = 0.153

Thus the mean male mouse internal doses of 0, 14.73, 145.99 and 1248.93 mg/kg/day wereconverted to equivalent human doses of 0, 2.12, 21.02 and 179.85 mg/kg/day, from which thepotency values were obtained (after deleting the high dose) by benchmark dose analysis usingthe quantal linear model. Thus the human oncogenic potency was 1.01x10-2 mg/kg/day-1 at the95% upper bound (based on the LED) and 5.03x10-3 mg/kg/day-1 at the maximum likelihoodestimate (based on the ED). The 95% UB potency value was used to calculate the oncogenicrisk from long term exposure to carbaryl (section V.C.2.).

Rats. Dietary exposure to carbaryl in rats resulted in transitional cell papillomas and transitionalcell carcinomas of the urinary bladder (both sexes), hepatocellular adenomas (females), thyroidfollicular cell adenomas and, possibly, follicular cell carcinomas (males) (Hamada, 1993a).These inductions were accompanied by hyperplasia, hypertrophy, squamous metaplasia, highmitotic index and / or atypia, which might be considered preneoplastic lesions.

With the possible exception of the liver tumors (see below), all tumor inductions occurred at thehigh dose (Table III-6c), which exceeded the MTD as determined by the large body weightdecrements occurring at that dose (35% in males, 45% in females by study termination), as wellas by the appearance of clinical signs and plasma, RBC and brain cholinesterase inhibition.Consequently, use of high dose data from this study for a quantitative risk evaluation was notindicated, as illness-inducing exposures may generate pharmacologic and/or metabolic profilesin the organism that are irrelevant to extended human exposures at low doses. There were,however, intimations of a rise in hepatocellular adenomas 13 in mid dose females, since the “atrisk” rate was 1/64, 0/70, 3/69 and 7/68* (*p<0.05). In addition, a reanalysis of pathology slidesconducted by the registrant and reported upon by US EPA (2002b) cited preneoplastic changes

14 These changes were not noted in the original report of Hamada, 1993a. Also, thehistopathology data from the terminal animals did not change significantly between the reports.

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at the mid and high doses in the week 53 interim sacrifice animals 14. These included not onlyliver lesions (hepatocellular hypertrophy in mid and high dose males and in high dose females),but also transitional epithelial hyperplasia of the urinary bladder (mid and high dose males andhigh dose females) and hyperplasia of the cuboidal epithelium lining the papillary surface of therenal pelvis (mid and high dose males). US EPA (2002b) stated in the case of the urinarybladder that actual tumors may eventually have developed had the mid dose of 1500 ppm beensomewhat higher:

The MDT [i.e., the mid dose tested of 1500 ppm] was judged to be belowadquate for testing the carcinogenic potential of carbaryl. At this dose, there wasno effect on body weight / body weight gain and only minor ChEI (less than 20%inhibition of plasma, RBC and brain ChE in males and females at week 53,except for 26% inhibition of RBC in females; at week 105, only female RBC andbrain ChE were decreased (22% and 16%, respectively). The CARC [the CancerAssessment Review Committee] noted that the MDT male rats had transitionalcell hyperplasia of the bladder, a preneoplastic lesion, at the week 53 necropsy.If the dose had been adequate, bladder tumors seen at the HDT may haveoccurred at the MDT. (US EPA, 2002b; p. 10)

However, despite US EPA's contention that the mid dose did not exceed an MTD, the 9% and18% body weight gain decrements in males and females, respectively, at that dose at 105weeks (calculated from the weight gain data in Table III-6a) suggested that the mid dose was atleast close to an MTD, as stated above in the summary of the study (section III.D.2.). Inaddition, the mid dose female hepatocellular adenoma incidence rate was similar to that in middose males, where there was no evidence of a dose-response relation for this tumor type (1/66,1/67, 3/69, 1/67 at ascending doses). This may reflect the fact that the 4.3% incidence rate atthat dose did not exceed the published historical control range of 0-6.3% for this tumor in femaleSprague-Dawley rats (CPRC, 1994, quoted in USEPA, 2002b). These considerations raised thepossibility that the mid dose incidence in females was either unrelated to carbaryl exposure oroccurred at a dose too high for consideration in a quantitative risk assessment.

One further point should be made with regard to the rat study. As noted above, the US EPAargued that the mid dose bladder preneoplasias at week 53 found in the reanalysis may havedeveloped into full tumors at a higher (but presumably still sub-MTD) dose. Their contention thatthe mid dose was below the MTD supported the qualitative relevance of the study to cancer riskassessment, particularly as the animals did develop bladder papillomas and carcinomas at theactual high dose. On the other hand, had the MTD been exceeded (as occurred at the highdose), it might have called into question the dosing regimen, and with it the relevance of thestudy to cancer risk assessment. DPR's view is that, while an MTD may have been approached,the multiplicity of tumors at the high dose combined with the presence of preneoplasias and thesuggestion of an effect on hepatocellular adenomas at the mid dose lended support to thequantitative potency analysis carried out in the mouse.

15 In actuality, the DEEM-FCID analysis considered 350 food items, all of which were derivedfrom the tolerances listed in the Federal Register (Volume 73, Number 176 - Sept. 10, 2008).

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B. DIETARY EXPOSURE ASSESSMENT

1. IntroductionUnder the California Food Safety Act (AB-2161; Bronzan and Jones [1989]), the Department ofPesticide Regulation conducts acute and chronic dietary exposure assessments to evaluate therisk of human exposure to a pesticide in food. Two separate approaches are used to estimatethe risk: (1) risk is determined for the total dietary exposure based on measured residue levelson all commodities with established federal tolerances, and (2) risk is estimated for exposure toan individual commodity at the tolerance level (see section VI. Tolerance Assessment).

Dietary exposure is the product of the amount of food that is consumed and the concentration ofthe pesticide residue in that food. The total exposure in an individual’s diet for a defined timeperiod is the sum of exposure from all foods consumed within that period, in various forms andas ingredients in processed food items.

Two distinct pieces of information are required to assess dietary exposure: (1) the amount ofthe pesticide residue in food, and (2) the food consumption (including drinking water). Forestimating the acute exposure either the highest residue values at or below the tolerance or thedistribution of residues are considered. In contrast, for chronic exposure the mean residuevalues are considered. Acute exposure is calculated on a per-user basis, which includes in thedistribution of exposures only the days of survey that at least one commodity with potentialpesticide residues is consumed. Chronic exposure to pesticides is generally calculated usingper-capita mean consumption estimates.

2. Consumption data and dietary exposureThe Dietary Exposure Evaluation Model (DEEM-FCID®, version 2.03; Exponent Inc.,http://www.exponent.com/home.html) was used as the dietary exposure software in thisanalysis. The food / drinking water consumption pattern was based on data generated by theUnited States Department of Agriculture (USDA) through its 1994-1998 Continuing Survey ofFood Intake by Individuals (CSFII). The 1994-1998 dataset included the 1994-1996 foodconsumption survey along with the 1998 Supplemental Children’s Survey (CSFII 1998). Riskestimates, expressed as margins of exposure (MOEs), were provided for the average USpopulation and 18 selected population subgroups. These subgroups were defined bygeographic regions, gender, ethnicity or age, and included infants (nursing and non-nursing)and children.

For acute exposure estimates, one-day consumption data comprised all of the several dozencommodities that carry tolerances for carbaryl. These include raw agricultural commdities, meat,dairy and drinking water (see Table IV-2) 15. In the initial analysis, the consumption of eachcommodity by each member of a population subgroup was multiplied by a single residue value(point estimate) to generate a deterministic risk assessment. This single residue value waseither the highest measured or, in cases in which no residues were detected, the limit ofdetection (LOD). In cases in which more than one LOD was used, as occasionally occurredwhen there were data for more than one year, the highest LOD was chosen.

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In order to refine the acute assessment toward a more representative probability of populationalexposure, the entire range of measured residue levels was then considered in a distributional(Monte Carlo) analysis. One-half of the LOD value was assigned to those samples in theresidue data file not yielding detectable residue levels (i.e., were below the LOD). In one case -olives - residue data came from a field trial in which all of the twelve samples registereddetections. These were used to construct an artificial RDF using a percent crop treated value of2% and setting all values except for the measured residue values to the LOD.

For chronic exposure estimates, the average food consumption of each population subgroupwas multiplied by the mean residue value. The dosage estimates for both acute and chronicexposure were expressed in units of ppm (µg/kg/day).

3. Exposure to carbaryl and 1-naphthol in foodResidue levels of carbaryl were determined for all food items with carbaryl tolerances, asindicated above. The tolerance values were published in the Federal Register (Volume 73,Number 176 - Sept. 10, 2008). Because the carbaryl metabolite 1-naphthol is included in thetolerances for all commodities except dillweed, an accounting of possible risks from exposure tothat compound was called for. The PDP system included 1-naphthol in its measurements for2004-2007. Far fewer measurements were made in the previous years, making the data fromthose years of limited value.

In 2004, carbaryl residues were detected in 396 of the 10,273 samples tested under PDP(3.9%), while 1-naphthol was detected in 26 of 1820 samples tested (1.4%). In 2005, carbarylresidues were detected in 343 of the 10,127 samples tested under PDP (3.4%), while 1-naphthol was detected in 32 of the 2796 samples tested (1.1%). In all cases in which 1-naphtholwas detected during this 2-year span, carbaryl was also detected, though the reverse was notthe case. This meant that the conditions that were likely to preserve naphthol in a givencommodity also preserved carbaryl.

In most instances in which both compounds were detected in 2004 and 2005, the parentcompound was present at higher levels than the degradate. Thus in 2004, for 23 of the 26 dualdetections the naphthol / carbaryl ratio was 0.37±0.22. For 3 of the 26 dual detections, naphtholresidues were higher than carbaryl (by 1.10-fold, 5.67-fold and 24.00-fold). In 2005, 24 of the 32dual detections showed higher carbaryl residues than naphthol, with a naphthol / carbaryl ratioof 0.50±0.25; eight of the 32 dual detections showed higher naphthol residues than carbaryl,with a ratio of 2.16±1.52. In 2005, four additional measurements were made in pork products, allof which showed serious over-tolerances for both carbaryl and 1-naphthol. The naphthol-to-carbaryl ratio for those samples was 1.33±1.05.

Though it is true that about two-thirds of the carbaryl-positive samples did not contain 1-naphthol at detectable levels, the variegated nature of the combined residue data rendersimpossible valid generalizations of the relative residues of the parent compound and degradate.All that can be said is that if the assumption is made that the two compounds are of equivalenttoxicity, the risks estimated when only carbaryl exposure is considered may be lower than the"actual" risk.

However, potential residues of the carbaryl metabolite 1-naphthol were not included in thisanalysis for the following reasons:

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1) The acute oral toxicity of 1-naphthol was substantially less than that forcarbaryl. The acute LD50 for 1-naphthol in rats was 2300-2590 mg/kg (SCCNFP[2001]), compared to LD50s for carbaryl of 233-840 mg/kg in the same species(section III.B.3. above).

2) The only available acute LOEL for 1-naphthol, 0.5 g/kg, based on death andhistopathologic changes in the kidneys and gut of rats (Poole and Buckley[1989]), was substantially higher than the critical acute LED10 of 0.25 mg/kg forcarbaryl, which was based on cholinergic signs and symptoms at a LOEL of 1mg/kg (Robinson and Broxup [1997]).

3) Subchronic oral toxicity was also observed at higher doses for 1-naphtholthan for carbaryl. Poole and Buckley (1989) established an oral subchronic LOELof 50 mg/kg/day for 1-naphthol in rats, based on weight gain decrements andpossible effects on white blood cell counts in females. While a critical subchronicNOEL or LED10 was not established in this assessment, and LED10 of 0.5mg/kg/day was noted based on dose-dependent inhibition of brain cholinesteraseactivity starting at a low dose of 3.4 mg/kg/day in the 1-yr dog dietary study ofHamada (1987).

4) As 1-naphthol results from the decarbamylation of carbaryl, the likelihood thatit is an effective cholinesterase inhibitor is low. This is an important considerationin view of the high probability that both the acute and chronic risk estimates werebased on cholinesterase inhibition. It should be noted, however, that themechanism of carbaryl-mediated carcinogenesis is not understood. If 1-naphtholis carcinogenic, and if it exerts its influence at the same dose as carbaryl, theoncogenic risk estimate obtained by considering carbaryl alone may beunderstated.

4. Residue data sourcesThe residue data for carbaryl used in this assessment were derived overwhelmingly from theUSDA’s Pesticide Data Program (PDP). Data collected by the Food and Drug Administrationwere used for blueberries and raspberries. Field trial residue studies submitted by carbarylregistrants to support tolerances were used for olives, olive oil, sunflower seeds and sunfloweroil.

The USDA Pesticide Data Program (www.ams.usda.gov/science/pdp/download.htm). ThePDP was specifically designed to generate pesticide residue data for risk assessments. Since1991, PDP data have been collected annually from ten states (including California) at producemarkets and chain store distribution centers close to the consumer level. As described in theAnnual Summary of the Pesticide Data Program for the 2007 calendar year, “PDP samplingprocedures were designed to capture residues in the food supply as close as possible to thetime of consumption. PDP concentrates its efforts to provide realistic pesticide residue data onfoods that are most often consumed by infants and children and incorporates recommendationsmade in 1993 by the National Academy of Sceinces (NAS) in its report ‘Pesticides in the Dietsof Infants and Children.’” The current assessment utilizes carbaryl residue data collected mostlybetween 2004 and 2007. Earlier PDP data were used in cases where more recent data were notavailable.

16 Walnuts, for which no PDP data were available, presented a unique case. The Tier 2 point estimate forwalnuts was taken from the almond point estimate value, as indicated in the surrogate methodology detailed here.However, the tolerance of 1 ppm for walnuts was 10-fold that of almonds (0.1 ppm), suggesting that the almondresidue value may have less relevance to walnuts than surrogates used for other commodities in this assessment, allof which bore the same tolerance as those commodities.

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PDP data were available for many of the commodities with established tolerances for carbaryl(Table IV-2). These were split in the DEEM-FCID® analysis into 350 total food items, eleven ofwhich were again split into subcategories ("food forms") for both the acute and chronic analysesdue to the availability of processing data on those forms and the conviction, borne out inpreliminary DEEM-FCID runs, that the data on those relatively highly-consumed commoditieswould materially affect the calculated exposure. With the exception of three commodities - cornsyrup, soybeans and finished drinking water - all of the PDP-based samples were collected inCalifornia. This resulted in risk estimates that bore particular relevance to California consumers.

For the Tier 2 / point estimate analysis, appropriate representative commodities (“surrogates”)originating from the same crop group were used in all cases in which residue data on a givencommodity were not available (see crop group tables, 40CFR 180.41).The high point estimatevalues were assigned to such commodities from monitored surrogates within the same cropgroup (Table IV-2) 16. For the Tier 3 / distributional analysis, the decision to use a surrogate wasbased on examination of the Critical Exposure Commodity (CEC) report for the Tier 2 andpreliminary Tier 3 analyses (see below). Where the CEC report indicated that there wassufficient consumption of a particular commodity to make a potentially substantial contribution tooverall exposure (i.e., greater than 5% of the total exposure), surrogate distribution data wereused. In all such Tier 3 cases, the crop treated value was set to 100%. The commodity /surrogate pairs used in the Tier 3 assessment were as follows: crop group 5B - turnip greens /collard; crop group 9A - honeydew melon / cantaloupe; crop group 11 - pear juice / pear; cropgroup 12 - apricot / nectarine; apricot juice / nectarine; dried apricot / nectarine; crop group 13A- raspberry juice / raspberry, blackberry juice / blackberry; crop group O - strawberry juice /strawberry.

Carbaryl residues were detected in at least one sample from the following commodities underPDP (except where another source is indicated): crop groups 1A and 1B - none; crop groups 1Cand 1D - frozen potato, sweet potato; crop group 2 - none; crop group 4A - lettuce, freshspinach; crop group 4B - celery; crop group 5A - broccoli; crop group 5B - collard, kale; cropgroup 6 - none; crop group 6A - bean (snap/succulent/frozen), pea (fresh/frozen/canned); cropgroup 6B - none; crop group 8 - eggplant, sweet bell pepper, tomato paste; crop group 9A -cantaloupe, watermelon; crop group 9B - cucumber, summer squash; crop group 10 - grapefruit,orange, orange juice; crop group 11 - apple, apple juice, apple sauce, pear; crop group 12 -cherry, nectarine, peach, plum (prune/fresh), plum (prune/dried); crop group 13A - raspberry(FDA); crop group 13B - blueberry (FDA); crop group 14 - none; crop group 15 - rice; crop group19A - none; crop group 20 - sunflower seed (field trial); crop group O - asparagus, banana,cranberry, grape, grape juice, olive (field trial), olive oil (field trial) onion, pineapple, strawberry,drinking water (“finished”); crop group M - pork fat, pork muscle; crop group D - milk, heavycream.

Carbaryl residues were not detected under PDP for the following commodities, necessitatinguse in those cases of the LOD for the point estimate determinations: crop groups 1A and 1B -

17 In the case of olives, an artificial RDF file was constructed assuming a total sample number of600. The 12 residue detect samples (i.e., every sample) along with the 2% crop treated value reported bythe USEPA (USEPA, 2007) were also used.

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carrot; crop groups 1C and 1D - potato, crop group 2 - none; crop group 4A - canned spinach;crop group 4B - none; crop group 5A - none; crop group 5B - none; crop group 6 - soybean;crop group 6A - beans (snap/succulent/canned); crop group 6B - none; crop group 8 - tomato;crop group 9A - none; crop group 9B - winter squash; crop group 10 - none; crop group 11 -none; crop group 12 - none; crop group 13A - none; crop group 13B - none; crop group 14 -almond; crop group 15 - sweet corn, corn syrup, wheat, wheat flour; crop group 19A - none; crop group 20 - sunflower oil (field trial); crop group O - peanut butter, bottled water; crop groupM - beef fat, beef liver, beef muscle; crop group D - none.

FDA monitoring program. The Food and Drug Administration monitors pesticide residues inimported foods and in domestic foods shipped via interstate commerce. FDA also collectsincidence and residue level data on particular commodity / pesticide pairings. These functionsare related to its tolerance enforcement mandate. Though some processed commodities areexamined, FDA generally samples unwashed whole raw agricultural commodities, unlike thePDP program. Domestic sampling is executed as close to the point of production as possible,while sampling of imports occurs at the point of entry into the USA. Raspberry and blueberryresidue data, which was supplied to DPR by the USEPA, originated with the FDA monitoringprogram.

Field trial data. Field trial studies are submitted by pesticide registrants to support the settingof tolerances. Because these studies are usually conducted under the maximum applicationrates for the proposed label, with sampling carried out on the treated commodities, field trialdata are not preferable to PDP or FDA data in the generation of dietary exposure analyses. Inthe current assessment, field trial data were used only in cases where data from the othersources were not available: sunflower seeds (Robinson [1995a]), sunflower oil (Robinson[1995b]) olives (Macy and Lee [1995])17 and olive oil (point estimate value supplied directly bythe USEPA [USEPA, 2007]).

Finally, one commodity with a tolerance, oysters, had no entry in the DEEM program and thuswas omitted from the analysis. While it was not expected that carbaryl exposure from oysterswould comprise a substantial part of the total dietary exposure to carbaryl, the absence of thiscommodity from DEEM was, at the very least, a possible source of underestimation of thatexposure.

5. Acute exposureDPR uses a tiered approach to estimate acute dietary exposure to pesticides (DPR [2002]).Each succeeding tier refines the residue values assigned to commodities in the preceding tier.Tier 1 employs the tolerance value for each commodity, while Tier 2 is based on the highestresidue value or limit of detection (LOD) for those same commodities. Tiers 1 and 2 represent“deterministic” approaches to exposure assessment. Tier 3 comprises the distributional (MonteCarlo) approach, by which the measured distribution of the residue values for a givencommodity, rather than a single point value, is taken into account (all tiers consider thedistribution of consumption in the various subpopulations). As is clearly evident for carbaryl, theTier 3 level of refinement was necessary to generate a realistic picture of the acute dietary

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exposure and potential risk. The results of the tiered approach are summarized in the followingparagraphs.

Tier 1. Setting commodity residues at tolerance levels resulted in total exposure estimatessubstantially higher than the level considered as health protective for all examinedsubpopulations based on the calculation of Margin of Exposure (MOE = LED10 / exposureconcentration) (data not shown). An MOE of 100 or greater is considered health protective incases such as this one in which the toxicity data come from experiments in laboratory animals.As it is extremely unlikely that all commodities within an eating occasion would contain residuesat the federal tolerance level, refinement of the exposure estimates in at the Tier 2 level wasnecessary.

Tier 2. Tier 2 utilized the highest of the measured residue values or LOD. In practice, thisrequired the following assumptions: (a) all consumed foods contained the highest reportedresidue below the tolerance, (b) pesticide residues below the LOD were equal to the LOD, (c)all crops with tolerances were treated with the pesticide, and (d) residue concentrations did notvary from the time of sampling to the time of consumption.

Table IV-2 provides the residue values used in Tier 2 for carbaryl. As noted above, PDP datawere used for the bulk of the commodities bearing tolerances, with field trial data used forolives, olive oil, sunflower seeds and sunflower oil, and FDA data used for raspberries andblueberries. With one exception, either the highest measured residue value or the highest LOD(i.e., when no residue was detected) was used as the final point estimate. In the case of cactus,for which no residue data were available from PDP, FDA or field trials, the highest of all of theLODs for any commodity used in DEEM, 0.025 ppm, was substituted for a point estimate.Oysters, for which a tolerance exists, were excluded from the analysis because DEEM-FCID®

had no category for that item.

Changes in food hydration state or processing will also alter residue concentrations from thosemeasured in the raw commodities. The following processing / dehydration multipliers were usedas they appear in the USEPA Revised dietary exposure analysis on carbaryl (USEPA [2007])and entered into the DEEM-FCID® Acute Module (version 2.03) as "adjustment factor 2": apples- juice (used in this assessment for pear juice but not apple juice, as PDP data were availableon the latter commodity): 0.37; apples - dried (used for apples and pears): 2.58; cabbage -cooking (used for cabbage, brussels sprouts and kohlrabi): 0.1; lemon peel: 1.16; orange peel:1.27; corn grain - corn oil: 0.25; olives - olive oil: 0.81; okra - cooking: 0.66; okra -cooking/steaming: 0.18 (used for frying and non-specific preparation); peas - cooking: 0.15;peanuts - peanut oil: 0.29; pineapple - pineapple juice and pineapple peeled fruit: 0.54; plums -dried: 0.15; potatoes - dried: 0.4; potatoes - fried: 0.04; potatoes - baked: 1.2; potatoes - boiled:2.5; rice - polished (white): 0.03; rice - bran: 0.4; soybean - oil: 0.005; sugarbeets (used forsugar and molassess): 0.04; tomatoes - puree (used for paste): 0.65; tomatoes - juice: 0.52;tomatoes - dried: 0.52; wheat - germ: 0.65; wheat - bran: 1.03.

In addition, default processing factors from DEEM® (version 7.6) were included in this analysis,as follows: apricots - dried: 6.0; bananas - dried: 3.9; beef - dried: 1.92; cherries - juice: 1.5;corn grain / sugar, high fructose corn syrup (used for corn syrup) - 1.5; cranberries - juice: 1.1;grapefruit - juice: 2.1; lemon - juice: 2.0; lime - juice: 2.0; peach - dried: 7.0; pineapple - dried:5.0; plum / prune - juice: 1.4; potato - flour: 6.5; tangerine - juice: 2.3.

18 In other words, inclusion of percent crop treated data allowed “non-detect” samples to be seteither at 0 mg/kg or at the LOD. This is explained in the calculation that appears in the next paragraph.

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In general, the highest exposures were predicted for infants and young children (1-2 yr and 3-5yr age groups in particular). Lower exposures were predicted for adults. Ethnicity andgeographic localization were of somewhat less importance than age for the Tier 2 analysis.Table IV-3 contains the point estimate exposures at the 95th and 99th user-day percentiles(defined as the estimated percentile of user-days falling below the calculated exposure).

The acute Critical Exposure Commodity (CEC) analysis identified blueberries, peaches,apricots, apples, asparagus, olives, grapes and strawberries as making substantial (i.e., >5%)contributions to the acute dietary exposure of the highest exposure groups (infants, children 1-2yr and children 3-5 yr) under Tier 2. The high contributing commodities in the US population asa whole included apples, asparagus and blueberries. For a complete Tier 2 contributor analysis,see Appendix VI-3.

Tier 3. Due to the low MOEs generated in the Tier 2 analysis (see section IV.C.5.a. below), adistributional (Monte Carlo) analysis was initiated as the next refining step of the acute dietaryexposure assessment. This approach combined pesticide residue and commodity consumptionto produce a distribution of potential exposures for the selected subpopulations. Theseexposure estimates, shown in Table IV-3, also incorporated information on the percentage ofthe crop that was treated with carbaryl (PCT), so that the actual use pattern for that crop wasreflected in the exposure patterns generated. PCT data for each commodity were taken directlyfrom USEPA's dietary analysis (USEPA, 2007), which in turn obtained the data from their ownBiological and Economical Analysis Division (BEAD). Several of the commodities wereconsidered to be “blended”, i.e., they contained contributions from many different harvests. PCTwas set to 100% for these commodities because it was assumed that there were potentialresidues in all samples 18. Included in the blended category were soybeans, tomato paste,orange juice, apple juice, apple sauce, grape juice, peanut butter, drinking water, bottled water,milk and heavy cream. PCT was also set to 100% for imported commodities (bananas andpineapples) and for all meat products.

Residue data files (RDFs) were constructed for all commodities for which there were adequatedata. Such files consisted of all of the residue values for that commodity, along with the totalnumber of samples assayed. The proportion of that total expected to have no residue at all wascalculated using the PCT value, with the remaining samples set to half of the LOD. Thus:

# @ 0.5xLOD = (total #) - (# @ zero + # with residue detections)

As with the point estimates, the Monte Carlo estimates were highest for infants (particularly non-nursing infants <1 yr) and young children in the 1-2 yr age group when assessing the 99.9th

percentile. At the 95th percentile, the “non-hispanic / non-white / non-black” population (assumedto be Asian) was also among the more highly exposed. The least exposed populations tendedto be older youths and adults.

The acute Critical Exposure Commodity (CEC) analysis identified cherries, rice, blueberries,peaches, pineapples, and plums as major contributors (i.e., >5%) for the infant and children 1-2yr subpopulations. For non-hispanic / non-white / non-black subpopulation, the major

135

contributors were chinese cabbage and mustard greens. For the US population as a whole,cherries and plums were the major contributors. For a complete contributor accounting in theMonte Carlo analysis, see Appendix VI-5.

6. Chronic exposureFor estimates of chronic exposure, the average value of all pesticide residues detected on acommodity was multiplied by the average annual consumption determined for eachsubpopulation. The population average daily consumption distribution was used to reflect theconsumption patterns of individuals over time. Residue levels below the LOD were set at 1/2 ofthat limit. PCT adjustments were not made for any commodity in the chronic analysis becausethe MOEs calculated assuming 100% PCT were greater than 100, obviating the need for furtherrefinement. Even so, estimated average PCT values from USEPA's Dietary Risk Assesment onCarbaryl (USEPA [2007]) were included in Table IV-2 (along with the calculated chronic residuelevels) for possible later use. As with the acute analysis, PDP was the predominant data sourcein the chronic analysis, except in cases where the data were based on field trials or FDA data.Calculations for oncogenicity using the 95% upper bound on the dose-tumor slope also usedthe chronic exposure data.

The DEEM-FCID®-generated chronic exposure estimates appear in Table IV-4. Children 1-2 yrexhibited the highest exposures, followed by non-nursing infants <1 yr and all infants. Exposurefor the US population as a whole was notably lower. Inspection of the CEC analysis indicatesthat stone fruits (apricots in particular) were the major contributors to chronic carbaryl exposurefor non-nursing infants <1 yr. For children 1-2 yr the major contributors were stone fruits andolives, while for all infants they were stone fruits. Olives were the main contributor for the USpopulation as a whole.

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Table IV-2. Anticipated Carbaryl Residues for Acute and Chronic Dietary Exposure Assessment - arrangement by crop group

Commodity Source of data Toler.(ppm)

detectedsamples / totalsamples

Detectedresidues (ppm)

LOD range(ppm)

PCT max - avg a

Acute residue (ppm) Chronicresidue (ppm) d

Pt. estimate b Monte Carlo c

Crop groups 1A and 1AB - Root vegetables

Carrot PDP, 2007PDP, 2006

.5 0 / 7440 / 744

n/a .002 - .006 6% - 4% 0.006 RDF1 0.001

Beets, garden (root)Beets, sugar (root)BurdockCeleriacChicory rootGinsengHorseradishParsley (turnip root)ParsnipRadishRadish (Oriental)RutabagaSalsify (root)Turnip (root)

PDP, 2007PDP, 2006

2 0 / 7440 / 744

n/a .002 - .006 100% - 100% 0.006 (carrot)

Crop group 1CD - Tuber and corm vegetables

Potato PDP, 2002PDP, 2001PDP, 2000

2 0 / 3700 / 7330 / 369

n/an/an/a

.008

.008

.008

3% - 2% 0.008 RDF2 0.004

Potato (frozen) PDP, 2007PDP, 2006

2 5 / 8000 / 744

.002n/a

.001 - .002 5% - <1% 0.002 RDF3 0.001

Sweet potato PDP, 2004PDP, 2003

0.2 0 / 6531 / 734

n/a.013

.002

.002 - .00838% - 17% 0.013 RDF4 0.002522

137

ArrowrootArtichoke, Jerusal.CassavaDasheen, cormGingerTanierTumeric, cormYam, trueYam bean

PDP, 2004PDP, 2003

0.2 0 / 6531 / 734

n/a.013

.002

.002 - .008100% - 100% 0.013 (sweet

potato)

Crop group 2 - Leaves of root and tuber vegetables

Beets, garden, topChicory, topDasheen leafRadish topRadish, Oriental topSalsify, top

PDP, 2006 22 8 / 511 .0005 - .093 .0003 - .002 100% - 100% 0.093 (freshspinach)

Crop group 4A - Leafy greens

Lettuce PDP, 2005PDP, 2004

10 1 / 7433 / 743

.004

.003 - .005.0003 - .002.001 - .002

4% - 2% 0.005 RDF5 0.001012

Spinach (fresh) PDP, 2006 22 8 / 511 .0005 - .093 .0003 - .002 2% - 1% 0.093 RDF6 0.001

Spinach (canned) PDP, 2004 22 0 / 371 n/a .008 2% - 1% 0.008 RDF7 0.0042

Dandelion leavesEndiveParsley leaves

PDP, 2006 22 8 / 511 .0005 - .093 .0003 - .002 100% - 100%

100% - 5%

0.093 (freshspinach)

Crop group 4B - Leafy petioles

Celery PDP, 2007 3 6 / 739 .0005 - 4.8 .0003 - .002 4% - 1% 4.8 f RDF8 0.001

CardoonCeltuceFennel, FlorenceRhubarbSwiss chard

PDP, 2007 3 6 / 739 .0005 - 4.8 .0003 - .002 100% - 100% 4.8 (celery) f 4.8 (celery) e, f

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Crop group 5A - Brassica: head and stem

Broccoli PDP, 2007PDP, 2006

10 2 / 7360 / 185

.001 - .003n/a

.001 6% - 3% 0.003 RDF9 0.0005

Broccoli, ChineseBrussels sproutCabbageCabbage, Chinese, napaCabbage, Chinese, mustardCauliflowerKohlrabi

PDP, 2007PDP, 2006

10 2 / 7360 / 185

.001 - .003n/a

.001 100% - 100%

5% - <1%

<2.5% - <1%

0.003 (broccoli)

Crop group 5B - Brassica: leafy greens

Collard PDP, 2007PDP, 2006

10 2 / 3530 / 86

.61 - 1.7n/a

.002 - .010

.002 / .01011% - 5% 1.7 RDF10 0.001

Kale PDP, 2007PDP, 2006

10 1 / 3830 / 98

.23n/a

.002 - .010

.002 - .0102% - 1% 0.23 RDF11 0.001

Broccoli raabCabbage, Chinese,bok choyMustard, greensRape, greensTurnip, greens

PDP, 2007PDP, 2006

10 2 / 3530 / 86

.61 - 1.7n/a

.002 - .010

.002 - .010100% - 100% 1.7 (collard) RDF80 (collard

data for turnipgreens only)

Crop group 6 - Soybean

Soybean PDP, 2005PDP, 2004

.5 0 / 6680 / 586

n/an/a

.003

.003100% - 100% /blended

0.003 RDF12 0.0015

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Crop group 6A - Edible-pod legume vegetables

Bean, snap,succulent (greenbeans)

Bean, snap,succulent, canned(green beans)

Bean, snap,succulent, frozen(green beans)

PDP, 2007PDP, 2005

PDP, 2004

PDP, 2005

10

10

10

7 / 7392 / 181

0 / 185

5 / 555

.011 - .32

.017 - .53

n/a

.003 - .071

.002 - .010

.002 - .010

.002 - .010

.002 - .010

14% - 10% 0.53

0.010

0.071

RDF71

RDF72

RDF73

0.001909

0.001

0.001088

Pea, edible podded,succulent (sweetpeas)

PDP, 2006 (frozen)PDP, 2003 (frozen)PDP, 2002 (can./froz.)PDP, 2001

10 1 / 7220 / 540 / 1220 / 54

.052n/an/an/a

.002 - .010

.008

.008

.008

1% - 1% 0.052 RDF74 0.002543

Crop group 6B - Dried shelled peas / beans (except soybeans)

Bean, black, seedBean, broad, seedBean, cowpea, seedBean, greatnorthern, seedBean, kidney, seedBean, lima, seedBean, mung, seedBean, navy, seedBean, pink, seedBean, pinto, seedChickpea, seedGuar, seedLentil, seedPea, dryPea, pigeon, seed

PDP, 2005PDP, 2004

.5 0 / 6680 / 586

n/an/a

.003

.003100% - 100% 0.003 (soybean)

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Crop group 8 - Fruiting vegetables

Eggplant PDP, 2006PDP, 2005

5 12 / 74022 / 736

.017 - .18

.017 - .14.010 13% - 9% 0.18 RDF13 0.007439

Sweet bell pepper PDP, 2004PDP, 2003PDP, 2002

5 40 / 55854 / 7419 / 186

.001 - .81

.002 - .65

.002 - .55

.001

.001

.001

12% - 5% 0.81 RDF14 0.025591

Tomato PDP, 2007 5 0 / 741 n/a .006 9% - 6% 0.006 RDF15 0.003

Tomato, paste(canned)

PDP, 2001 5 2 / 369 .018 - .043 .011 100% - 100% /blended

0.043 RDF16 0.0055

Okra PDP, 2004PDP, 2003PDP, 2002

5 40 / 55854 / 7419 / 186

.001 - .81

.002 - .65

.002 - .55

.001

.001

.001

100% - 100% 0.81 (sweet bellpepper)

Tomatillo PDP, 2007 5 0 / 741 n/a .006 100% - 100% 0.006 (tomato)

Tomato canned andpuree

PDP, 2001 5 2 / 369 .018 - .043 .011 100% - 100% 0.043 (tomato,canned)

RDF16 (cannedtomato pastedata)

Crop group 9A - Curcurbits: melons

Cantaloupe PDP, 2005PDP, 2004

3 20 / 55826 / 742

.003 - .11

.003 - .61.002 - .008.002 - .008

13% - 9% 0.61 RDF17 0.001896

Watermelon PDP, 2006PDP, 2005

3 1 / 5500 / 182

.007n/a

.002 - .010

.002 - .01012% - 8% 0.007 RDF18 0.001

CasabaHoneydew melon

PDP, 2005PDP, 2004

3 20 / 55826 / 742

.003 - .11

.003 - .61.002 - .008.002 - .008

100% - 100% 0.61(cantaloupe)

RDF78(cantaloupedata forhoneydew only)

Crop group 9B - Curcurbits: squash / cucumbers

Cucumber PDP, 2004PDP, 2003PDP, 2002

3 14 / 55726 / 73911 / 183

.003 - .043

.013 - .20

.013 - .063

.002 - .010

.008

.008

22% - 7% 0.20 RDF19 0.003901

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Squash, summer PDP, 2007PDP, 2006

3 1 / 7420 / 186

.003n/a

.002 - .006

.002 - .00624% - 13% 0.003 RDF29 0.001010

Squash, winter PDP, 2006PDP, 2005PDP, 2004

3 0 / 3690 / 7310 / 364

n/an/an/a

.002 - .008

.002 - .008

.002 - .008

24% - 13% 0.008 RDF30 0.001

Balsam pearChayote fruit

PDP, 2004PDP, 2003PDP, 2002

3 14 / 55726 / 73911 / 183

.003 - .043

.013 - .20

.013 - .063

.002 - .010

.008

.008

100% - 100% 0.20(cucumber)

Chinese waxgourdPumpkin

PDP, 2006PDP, 2005PDP, 2004

3 0 / 3690 / 7310 / 364

n/an/an/a

.002 - .008

.002 - .008

.002 - .008

100% - 100% 0.008 (wintersquash)

Crop group 10 - Citrus fruits

Grapefruit PDP, 2006PDP, 2005

10 3 / 74313 / 719

.003

.003 - .039.002 - .006.002 - .006

11% - 6% 0.039 RDF31 0.001018

Orange PDP, 2005PDP, 2004

10 14 / 74114 / 742

.003 - .12

.003 - .059.002 - .010.002 - .010

4% - 2% 0.12 RDF32 0.001536

Orange juice PDP, 2006PDP, 2005PDP, 2004

10 165 / 55740 / 74421 / 186

.002 - .016

.003 - .017

.003 - .010

.001 - .010

.002 - .010

.002 - .010

100% - 100% /blended

0.017 RDF33 0.001581

Grapefruit juice PDP, 2006PDP, 2005

10 3 / 74313 / 719

.003

.003 - .039.002 - .006.002 - .006

100% - 100% 0.039(grapefruit)

Citrus citronCitrus hybridCitrus oilKumquatLemonLemon juiceLimeLime juicePummeloTangerineTangerine juice

PDP, 2005PDP, 2004

10 14 / 74114 / 742

.003 - .12

.003 - .059.002 - .010.002 - .010

100% - 100%

<2.5% - <1%

10% - 5%

0.12 (orange)

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Crop group 11 - Pome fruits

Apple PDP, 2005PDP, 2004

12 53 / 74366 / 744

.0005 - .32

.0005 - .49.0003 - .002.0003 - .002

35% - 24% 0.49 RDF34 0.005804

Apple juice PDP, 2007 12 14 / 368 .003 - .031 .002 - .020 100% - 100% /blended

0.031 RDF35 0.001937

Apple sauce PDP, 2006 12 165 / 744 .0005 - .23 .0003 - .002 100% - 100% /blended

0.23 RDF36 0.003683

Pear PDP, 2005PDP, 2004

12 61 / 55541 / 741

.003 - .33

.003 - .46.002 - .010.002 - .010

5% - 3% 0.46 RDF37 0.004646

CrabappleLoquatQuince

PDP, 2005PDP, 2004

12 53 / 74366 / 744

.0005 - .32

.0005 - .49.0003 - .002.0003 - .002

100% - 100% 0.49 (apple)

Pear juice PDP, 2005PDP, 2004

12 61 / 55541 / 741

.003 - .33

.003 - .46.002 - .010.002 - .010

5% - 1% 0.46 (pear) RDF37 (pear)

Crop group 12 - Stone fruits

Cherry PDP, 2007 10 68 / 419 .003 - .84 .002 - .004 33% - 22% 0.84 RDF38 0.026422

Nectarine PDP, 2007 10 35 / 563 .010 - 1.5 .006 13% - 6% 1.5 RDF39 0.010707

Peach PDP, 2007PDP, 2006

10 87 / 55525 / 90

.002 - .67

.002 - .45.001 - .002.001 - .002

13% - 6% 0.67 RDF40 0.008962

Plum (prune, fresh) PDP, 2006PDP, 2005

10 50 / 51549 / 573

.017 - .56

.017 - .11.010.010

8% - 5% 0.56 RDF41 0.006179

Plum (dried) PDP, 2006PDP, 2005

10 1 / 2247 / 153

.043

.017 - .45.010.010

5% - <1% 0.45 RDF42 0.005

Cherry juice PDP, 2007 10 68 / 419 .003 - .84 .002 - .004 100% - 100% 0.84 (cherry)

ApricotApricot (dried)

PDP, 2007 10 35 / 563 .010 - 1.5 .006 100% - 100% 1.5 (nectarine) RDF77(nectarine)

Peach juice PDP, 2007PDP, 2006

10 87 / 55525 / 90

.002 - .67

.002 - .45.001 - .002.001 - .002

100% - 100% 0.67 (peach)

Plum, prune, freshPlum, prune, juice

PDP, 2006PDP, 2005

10 50 / 51549 / 573

.017 - .56

.017 - .11.010.010

100% - 100% 0.56 (plum)

143

Crop group 13A - Caneberry group

Raspberry FDA, year not known j 10 51 / 247 .005 - 3.79 not known j 7% - 3% 3.79 RDF43 0.092575

Raspberry juice FDA, year not known j 10 51 / 247 .005 - 3.79 not known j 7% - 3% 3.79 RDF43(raspberry)

0.092575

BlackberryBlackberry juiceBoysenberryDewberryLoganberry

FDA, year not known j 10 51 / 247 .005 - 3.79 not known j 100% - 100% 3.79 (raspberry) RDF79(raspberry datafor blackberryand blackberryjuice only)

Crop group 13B - Bushberry group

Blueberry FDA, year not known j 10 23 / 212 .005 - 9.7 .002 44% - 22% 9.7 RDF44 0.094618

CurrantElderberryGooseberryHuckleberry

FDA, year not known j 10 23 / 212 .005 - 9.7 .002 100% -100% 9.7 (blueberry)

Crop group 14 - Tree nuts

Almond PDP, 2007 0.1 0 / 361 n/a .015 1% - 1% 0.015 RDF45 0.0075

Brazil nutButternutCashewChestnutFilbertHickory nutMacademia nutPecanPistachioWalnut k

PDP, 2007 0.1

1

0 / 361 n/a .015 100% -100%

15% - 10%5% - 5%

0.015 (almond)

Crop group 15 - Cereal grains

144

Sweet corn PDP, 2003 (frozen)PDP, 2002 (can./froz.)PDP, 2001 (canned)

.02 0 / 5470 / 7270 / 181

n/an/an/a

.008

.008

.008

1% - 1% 0.008 RDF48 0.004

Corn syrup PDP, 1998PDP, 1999

5 0 / 2980 / 140

n/an/a

.006

.0061% - 1% 0.006 RDF49 0.003

Rice PDP, 2000PDP, 2001PDP, 2002

5 3 / 17811 / 4362 / 417

.010 - .040

.010 - .038

.010

.006

.006

.006

1% - 1% 0.040 RDF50 0.003548

Wheat PDP, 2006PDP, 2005

1 0 / 6870 / 634

n/an/a

.006

.0061% - 1% 0.006 RDF51 0.003

Wheat flour PDP, 2003PDP, 2004

3 0 / 6060 / 725

n/an/a

.006

.0061% - 1% 0.006 RDF52 0.003

Sorghum grainSorghum syrup

PDP, 2003 (frozen)PDP, 2002 (can./froz.)PDP, 2001 (canned)

.02 0 / 5470 / 7270 / 181

n/an/an/a

.008

.008

.008

0.008 (sweetcorn)

Millett PDP, 2006PDP, 2005

1 0 / 6870 / 634

n/an/a

.006

.0060.006 (wheat)

Crop group 19A - Herbs

DillweedParsley, dried leaf

PDP, 2006 22 8 / 511 .0005 - .093 .0003 - .002 100% - 100% 0.093 (freshspinach)

Crop group 20 - Oilseed

Sunflower seed Field trial, 1995 h .5 8 / 20 <.02 - .129 .02 100% - 100% /blended

0.129

Sunflower oil Field trial, 1995 i 1 0 / 4 n/a <.02 7 100% - 100% /blended

0.02

Flaxseed oil Field trial, 1995 1 0 / 4 n/a <.02 7 100% - 100% 0.02 (sunfloweroil)

Crop group O - Other

145

Asparagus PDP, 2003PDP, 2003 (canned)PDP, 2002

15 5 / 3510 / 3546 / 708

.013 - 2.5n/a.020 - 15

.008 - .010

.008 - .010

.008 - .020

45% - 35% 15 - fresh

0.010 - canned

RDF53RDF54(canned)

0.0046650.004609(canned)

Banana PDP, 2007PDP, 2006

5 1 / 7441 / 742

.003

.003.002 - .010.002 - .010

100% - 100%(imported)

0.003 RDF55 0.001012

Cactus (prickly pearfruit and pad)

no measurements 5 forfruit, 12for pad

n/a n/a n/a 100% - 100% 0.025 0.025

Cranberry PDP, 2006 3 12 / 316 .003 .002 - .018 68% - 32% 0.003 RDF56 0.001267

Grape PDP, 2005PDP, 2004

10 34 / 73935 / 738

.003 - .47

.003 - .58.002 - .010.002 - .010

10% - 7% 0.58 RDF57 0.00915

Grape juice PDP, 1999PDP, 1998

10 290 / 714245 / 665

.003 - .086

.007 - .044.002 - .025.004 - .025

100% - 100% /blended

0.086 RDF58 0.004838

Raisin PDP, 2007PDP, 2006

10 4 / 3729 / 372

.003 - .12

.008 - .036.002 - .006.002 - .006

10% - 7% 0.12 RDF59 0.001051

Olive Field trial, 1995 g 10 12 / 12 .83 - 9.83 .01 2% - 1% 9.83 RDF76

Olive oil Field trial USEPA (2007b) cited - details of study not available 0.077 0.077

Peanut butter PDP, 2006 .05 0 / 739 n/a .010 100% - 100% /blended

0.010 RDF60 0.005

Pineapple PDP, 2000PDP, 2001PDP, 2002

2 4 / 3647 / 7309 / 360

.017 - .043

.013 - .060

.013 - .11

.008 - .010

.008 - .010

.008 - .010

100% - 100%(import)

0.11 RDF61 0.004927

Strawberry PDP, 2005PDP, 2004

4 21 / 73336 / 729

.003 - .44

.003 - 1.1.002.002

27% - 17% 1.1 RDF62 0.003625

Water, drinking(“finished water”)

PDP, 2007PDP, 2006PDP, 2005

no tol. 0 / 3690 / 3651 / 374

n/an/a19 ppt

12 - 23 ppt 12 - 23 ppt4.7 - 23 ppt

100% - 100% 0.000019 RDF63 0.000009

Water, bottled PDP, 2006PDP, 2005

no tol. 0 / 3670 / 211

n/an/a

7.5 ppt7.5 ppt

100% - 100% 0.0000075 RDF64 0.000004

Peanut PDP, 2006 .05 0 / 739 n/a .010 0.010 (peanutbutter)

0.010 (peanutbutter data)

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Strawberry juice PDP, 2005PDP, 2004

4 21 / 73336 / 729

.003 - .44

.003 - 1.1.002.002

27% - 17% 1.1 RDF62(strawberrydata)

Crop group M - Meat

Beef, fat18 PDP, 2001PDP, 2002

.5 0 / 2700 / 301

n/a 14 ppb14 ppb

100% - 100% 0.014 0.014 0.007

Beef, liver PDP, 2001PDP, 2002

3 0 / 3110 / 313

n/a 3.6 ppb 100% - 100% 0.0036 0.0036 0.0018

Beef, muscle PDP, 2001PDP, 2002

1 0 / 2850 / 310

n/a 3.6 ppb 100% - 100% 0.0036 0.0036 0.0018

Pork, fat PDP, 2005 .5 7 / 352 .001 - .0986 .0006 100% - 100% 0.0986 0.0986 0.003

Pork, muscle PDP, 2005 1 10 / 352 .0005 - .0066 .30 100% - 100% 0.0066 0.0066 0.000182

Goat, meatHorse, meatSheep, meat

PDP, 2001PDP, 2002

1 0 / 2850 / 310

n/a 3.6 ppb 100% - 100% 0.0036 (beefmuscle)

Beef, meat by-productsBeef, kidneyGoat, meat by-productsGoat kidneyGoat liverSheep, meat by-productsSheep kidneySheep liver

PDP, 2001PDP, 2002

3 0 / 3110 / 313

n/a 3.6 ppb 100% - 100% 0.0036 (beefliver)

Goat fatSheep fat

PDP, 2001PDP, 2002

.5 0 / 2700 / 301

n/a 14 ppb14 ppb

100% - 100% 0.014 (beef fat)

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Crop group D - Dairy products

Milk PDP, 2005PDP, 2004

1 2 / 7460 / 739

.000083n/a

.000050

.00012100% - 100% /blended

0.000083 RDF70 0.000043

Milk (heavy cream) PDP, 2007PDP, 2005

0.3 0 / 7422 / 369

n/a.0008 - .0036

.025

.0005100% - 100% /blended

0.0036 RDF75 0.008384

Note: this table includes only the most significant crops in the appropriate crop groups. For a complete listing of commodities included in the dietaryanalysis, see Appendix xxx.

a Percent crop treated data were retrieved from the USEPA’s Acute, Probabilistic Aggregate Dietary (Food and Drinking Water) Exposure and RiskAssessments for the Reregistration Eligibility Decision (USEPA, 2007a). "Max" refers to the estimated maximum value used for the acuteassessment. "Avg" refers to the weighted average value used for the chronic assessment. Both values are listed for each commodity ("max" valuefirst, then "avg" value), as indicated by the USEPA data. If surrogate data are used, it is so indicated.b Point estimates, expressed in units of ppm (µg/kg/day), represent the highest residue detection value measured from any of the latest 1-3 years ofPDP testing. If insufficient data were available from these years, earlier data were accessed. In cases for which neither PDP data nor a suitablereplacement crop were available, FDA or field test data were consulted. In cases in which no residues were detected, the highest Limit of Detectionvalue was used as the point estimate. For PDP-based data, nearly all commodities were sampled in California. The exceptions to this were cornsyrup, soybeans and “finished” drinking water. Surrogates were used within crop groups.c Monte Carlo estimations were carried out using residue data files (RDFs) set up for each commodity for which residue distribution data wereavailable. In cases where a surrogate was used, it is indicated in parentheses under the RDF number in this column.d Chronic residue estimates represent the average of all measured residue values. In the case of non-detections, one-half of the LOD value wasused. Percent crop treated data were not applied to the chronic residue calculation.e When surrogates were used in the Monte Carlo analysis, percent crop treated values were set to 100%.f Acute point estimates for celery and for commodities which used celery PDP data were set at the celery tolerance of 3 ppm because of thetolerance excedence measurement of 4.8 ppm. Monte Carlo and chronic estimations utilized the entire residue data set for celery.g Olive field trial: Macy and Lee (1995)h Sunflower seed field trial: Robinson (1995a)i Sunflower oil field trial: Robinson (1995b)

j Residue data for various types of berries were provided by the USEPA.k The Tier 2 point estimate for walnuts, which used almond data as a surrogate, presented a unique case. See text footnote #16.

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149

Table IV-3. Acute dietary exposure to carbaryl: point estimates and Monte Carlo estimates a

Point estimates, mg/kg/day Monte Carlo estimates, mg/kg/day

Population subgroup 95th percentile b

99th percentile

95th percentile b

99th percentile

99.9th

percentile

1. US population .006153 .015857 .000432 .001579 .006066

2. Western region .007187 .017583 .000551 .001968 .007500

3. Hispanics .005234 .011574 .000511 .001827 .007651

4. Non-hispanic whites .006434 .017359 .000391 .001410 .006483

5. Non-hispanic blacks .005274 .010680 .000447 .001544 .005429

6. Non-hispanic / non-white / non-black

.007145 .013094 .001059 .003179 .005331

7. All infants .014589 .037382 .000661 .002532 .010644

8. Nursing infants <1 yr .013898 .026562 .000431 .001308 .004201

9. Non-nursing infants <1yr

.014953 .037608 ..000771 ..002810 .012796

10. Females 13+ (preg./notlact.) c

.004960 .010054 .000373 .001983 .001991

11. Females 13+ (lactating) c .004357 .008433 .000334 .000639 .001439

12. Children 1-2 yr .014194 .031084 .000905 .002291 .010476

13. Children 3-5 yr .011654 .024534 .000799 .002066 .008455

14. Children 6-12 yr .007621 .018623 .000524 .001393 .007275

15. Youth 13-19 yr .004087 .011155 .000357 .001209 .004290

16. Adults 20-49 yr .004308 .011805 .000345 .001255 .003584

17. Adults 50+ yr .005240 .015709 .000329 .002170 .007442

18. Females 13-49 yr .004568 .012001 .000325 .001240 .003564

19. M/F 16-70 yr .004546 .012049 .000344 .001403 .004354a These estimates were generated by the DEEM-FCID® program, which utilized consumption data from1994-1996 USDA food consumption survey along with the 1998 Supplemental Children’s Survey (CSFII1998). Point estimates from the PDP program were the high estimates or high LODs on each commoditybearing a tolerance that was assayed in that program. Monte Carlo analysis was based on 500 iterations,a seed number of 10, and incorporated PCT data on non-blended residue distributions (PCT was set to100% for blended commodities). All residue distribution files (RDFs) came from the PDP data base, withthe exception of the artificial RDF constructed for olives, which utilized field trial data, and the RDFs forraspberries and blueberries, which originated with the FDA.b Estimated percentile of user-days falling below the calculated exposure.c The total number of user days for “Females 13+ (preg./not lactating)” and “Females 13+ (lactating)” were140 and 80, respectively. These sample sizes were very small compared to the other subpopulations, for

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which the total user days ranged between 583 (“Nursing infants <1 yr”) and 40,223 (“US population”). Therepresentativeness of the two former populations was therefore subject to uncertainty.

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Table IV-4. Chronic dietary exposure to carbaryl

Chronic exposure estimates, PDP datamg/kg/day aPopulation subgroup

1. US population 0.000287

2. Western region 0.000364

3. Hispanics 0.000266

4. Non-hispanic whites 0.000291

5. Non-hispanic blacks 0.000251

6. Non-hispanic / non- white / non-black 0.000379

7. All infants 0.000503

8. Nursing infants <1 yr 0.000235

9. Non-nursing infants <1 yr 0.000604

10. Females 13+ (preg./not lact.) 0.000193

11. Females 13+ (lactating) 0.000244

12. Children 1-2 yr 0.000655

13. Children 3-5 yr 0.000483

14. Children 6-12 yr 0.000322

15. Youth 13-19 yr 0.000225

16. Adults 20-49 yr 0.000253

17. Adults 50+ yr 0.000263

18. Females 13-49 yr 0.000249

19. Males/Females 16-70 yr (Not reported: DEEM-FCID® did not include this populationin its chronic program)

a All non-detects were set at half of the highest LOD value measured for each commodity.

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C. RISK CHARACTERIZATION

1. Acute risk estimation - deterministic and distributional approachesAcute dietary risk estimates using the deterministic (point estimate) and distributional (MonteCarlo) exposure predictions appear in Table IV-5. This table contains MOEs derived from thelargely PDP-based exposure estimates. Both critical regulatory values used to assess acute risk - the acute NOEL of 1 mg/kg and the acute LED10 of 0.25 mg/kg - were derived from the ratdevelopmental neurotoxicity study of Robinson and Broxup (1997). The former value was basedon clear FOB signs and statistically significant on body weight gain decrements at 10 mg/kg.The latter was based on the induction of slight hypotonic gait at 1 mg/kg. These endpoints wererelevant to dietary assessment because they were established in a study that employed oralgavage as the route of exposure.

NOEL = 1 mg/kg. Tier 2 / point estimate-derived acute MOEs (Table IV-5) calculated using aNOEL of 1 mg/kg were below the health protective standard of 100 for several subpopulationsat the 95th user day percentile. These included all infants (MOE=68), nursing infants <1 yr(MOE=68), non-nursing infants <1 yr (MOE=64), children 1-2 yr (MOE=68) and children 3-5 yr(MOE=84). At the 99th user day percentile, all populations except for lactating females 13+ hadMOEs less than 100, with MOEs reaching as low as 24 for all infants and non-nursing infants <1yr. A refined Tier 3 / Monte carlo analysis was triggered because of these low values.

As expected, the Monte Carlo-derived MOEs were higher than the corresponding pointestimates, commensurate with their lower calculated exposures. There were no subpopulationsexhibiting MOEs below 100 at the 95 or 99th user day percentiles using Monte Carlo analysis.However, at the 99.9th percentile, three subpopulations showed MOEs below 100: all infants(MOE=91), non-nursing infants <1 yr (MOE=76) and children 1-2 (MOE=92).

LED10 = 0.25 mg/kg. As the Tier 2 / point estimate data show (Table IV-5), all subpopulationsexhibited acute MOEs less than the health protective standard of 100 at the 95th and 99th userday percentiles. The lowest MOEs at any percentile were found among infants, reaching 6 atthe 99th percentile and 16 at the 95th percentile for non-nursing infants <1 yr. Furthermore,MOEs of 6 and 19 at the 99th and 95th percentiles, respectively, were determined for allinfants, and 9 and 17 for nursing infants <1 yr. Because these values were so low, Tier 3 /Monte Carlo analysis was triggered.

Again, the Monte Carlo-derived MOEs were higher than the corresponding point estimates dueto their lower calculated exposures. Even so, with two exceptions, all MOEs at the 99.9thpercentile fell below the health-protective standard of 100 (those exceptions, females 13+pregnant / non-nursing and females 13+ years nursing, did not provide reliable exposureestimates due to the very low number of user days available for analysis - see footnote “c”,Table IV-3). As with the point estimate data, the lowest MOEs occurred among infants andyoung children 1-2 years, reaching 19 for non-nursing infants <1 yr at the 99.9th percentile.Even at the 99th percentile there were many subpopulations registering MOEs below 100,including one (non-hispanic non-white non-black) that included adults. All subpopulationsshowed MOEs greater than 100 at the 95th percentile in the Monte Carlo analysis.

2. Chronic risk estimation

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Chronic dietary risk estimates appear in Table IV-6. The chronic LED10 of 0.5 mg/kg/day(ED10=1.7 mg/kg/day) was used to assess chronic dietary risk. It was determined by applyingbenchmark dose modeling (Hill algorithm) to the brain cholinesterase activity profile in femalebeagle dogs after 52 weeks of dietary exposure to carbaryl (Hamada [1987]). Statisticallysignificant inhibition was noted at all doses, including the low dose of 3.7 mg/kg/day. As theMOEs ranged between 827 (non-nursing infants <1 yr) and over 2000 (including, interestingly,nursing infants), a chronic dietary health concern was not indicated.

3. Oncogenic risk estimationThe oncogenic dietary risk estimate for the US population also appears in Table IV-6. The 95%upper bound potency estimate of 1.01x10-2 mg/kg/day-1 (quantal linear algorithm) was used inthis calculation. The resulting risk value, 2.90x10-6 for the US population, exceeded the targetvalue of 10-6 used to distinguish negligible and non-negligible levels of oncogenic risk in adultpopulations. The highest risk level of 3.83x10-6 was calculated for the non-hispanic / non-white /non-black subpopulation. The lowest risk level of 2.54x10-6 was calculated for the non-hispanicblack subpopulation.

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Table IV-5. Acute dietary margins of exposure calculated using two regulatory endpoint valuesand two approaches to exposure estimation (point estimate and Monte Carlo a)

Point estimate MOEs b Monte Carlo MOEs b

Population subgroup 95th percentile c

99th percentile

95th percentile c

99th percentile

99.9th

percentile

1. US population 160 / 40 60 / 15 2312 / 578 632 / 158 164 / 41

2. Western region 136 / 34 56 / 14 1812 ./ 453 508 / 127 132 / 33

3. Hispanics 188 / 47 84 / 21 1956 / 489 544 / 136 128 / 32

4. Non-hispanic whites 152 / 38 56 / 14 2552 / 638 708 / 177 152 / 38

5. Non-hispanic blacks 188 / 47 92 / 23 2236 / 559 644 / 161 184 / 46

6. Non-hispanic / non-white / non-black

136 / 34 67 / 19 940 / 235 312 / 78 184 / 46

7. All infants 68 / 17 24 / 6 1512 / 378 392 / 98 92 / 23

8. Nursing infants <1 yr 68 / 17 36 / 9 2316 / 579 764 / 191 236 / 59

9. Non-nursing infants <1yr

64 / 16 24 / 6 1296 / 324 352 / 88 76 / 19

10. Females 13+ (preg./notlact.) d

200 / 50 96 / 24 2680 / 670 504 / 126 500 / 125

11. Females 13+ (lactating)d 228 / 57 116 / 29 2996 / 749 1564 / 391 692 / 173

12. Children 1-2 yr 68 / 17 32 / 8 1104 / 276 436 / 109 92 / 23

13. Children 3-5 yr 84 / 21 40 / 10 1252 / 313 484 / 121 116 / 29

14. Children 6-12 yr 128 / 32 52 / 13 1908 / 477 716 / 179 136 / 34

15. Youth 13-19 yr 244 / 61 88 / 22 2800 / 700 824 / 206 232 / 58

16. Adults 20-49 yr 232 / 58 84 / 21 2900 / 725 796 / 199 276 / 69

17. Adults 50+ yr 188 / 47 60 / 15 3032 / 758 460 / 115 132 / 33

18. Females 13-49 yr 216 / 54 80 / 20 3076 / 769 804 / 201 280 / 70

19. M/F 16-70 yr 216 / 54 80 / 20 2900 / 725 712 / 178 228 / 57a For details regarding the inputs to the DEEM-FCID® program, see the text and footnote “a”, Table IV-3.b MOE (margin of exposure) = NOEL / exposure dose or LED10 / exposure dose. The NOEL = 1 mg/kg; theLED10 = 0.25 mg/kg. The first value in the top line of each box represents the MOE calculated with the 1mg/kg NOEL, the second with the 0.25 mg/kg LED10. The precise MOE may differ slightly from thequotient of the NOEL (or LED) ÷ exposure dose due to rounding. This may be accented with the 1 mg/kgMOE because it was calculated by multiplying the DEEM-derived 0.25 mg/kg MOE by 4. c Estimated percentile of user-days falling below the calculated exposure.d See footnote “c”, Table IV-3.

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Table IV-6. Chronic dietary margins of exposure (MOEs) and oncogenic risk values

Chronic MOEs a, PDP datamg/kg/day

Oncogenic risk a

Population subgroup

1. US population 1741 2.90x10-6

2. Western region 1373 3.68x10-6

3. Hispanics 1882 2.68x10-6

4. Non-hispanic whites 1719 2.94x10-6

5. Non-hispanic blacks 1990 2.54x10-6

6. Non-hispanic / non-white / non-black

1320 3.83x10-6

7. All infants 995 not reported

8. Nursing infants <1 yr 2128 not reported

9. Non-nursing infants<1 yr

827 not reported

10. Females 13+(preg./not lact.) 3

2590 not reported

11. Females 13+(lactating) 3

2046 not reported

12. Children 1-2 yr 763 not reported

13. Children 3-5 yr 1036 not reported

14. Children 6-12 yr 1554 not reported

15. Youth 13-19 yr 2219 not reported

16. Adults 20-49 yr 1973 not reported

17. Adults 50+ yr 1903 not reported

18. Females 13-49 yr 2004 not reported

19. Males/Females 16-70 yr

Not reported: DEEM-FCID® does not includethis population in its chronic program.

not reported

a The DEEM-FCID® program was used with the following input parameters: critical chronic LED10=0.5mg/kg/day, 95% upper bound on oncogenic potency = 1.00 x 10-3 mg/kg/day-1

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V. RISK APPRAISAL

Risk assessment is the process by which the toxicity of a compound is compared to thepotential for human exposure under specific conditions, in order to estimate the possible risk tohuman health. Every risk assessment has inherent limitations relating to the relevance andquality of the available toxicity and exposure data. Assumptions and extrapolations areincorporated into the hazard identification, dose-response assessment and exposure-assessment processes. This results in uncertainty in the risk characterization, which integratesthe information from the preceding three processes. Qualitatively, risk assessments for allchemicals have similar uncertainties. However, the magnitude of the uncertainty varies with theavailability and quality of toxicity and exposure data, and the relevance of that data to theanticipated exposure scenarios;

In the following sections, the specific areas of uncertainty associated with the characterization ofhealth risks from dietary exposure of both workers and the general public to carbaryl and itsprimary metabolite are described.

A. HAZARD IDENTIFICATION

Selection of the appropriate laboratory animal toxicity studies to characterize human risk is acentral task of pesticide risk assessment. Two factors influence the selection process: (1) thescientific quality of the studies in question, including the reliability of the data used to supportthe selection of critical LOELs, NOELs and LEDs, and (2) the relevance of the routes ofexposure employed in those studies to the anticipated routes of human exposure in the field.These factors are discussed in the following sections as they relate to acute and annual(chronic) exposure to carbaryl.

1. Non-oncogenic effectsa. Acute oral toxicity

NOEL = 1 mg/kg. Acutely induced FOB signs - slight tremors, slight hypotonic gait, slight ataxicgait and pinpoint pupils - combined with body weight gain decrements in pregnant rats at agavage dose of 10 mg/kg (Robinson and Broxup, 1997) formed the basis for the critical acuteNOEL determination for carbaryl. The strength of this determination lay partly in the clarity of theincidence data - their statistical significance and unarguably acute nature - and partly in thesupport forthcoming from three additional acute oral gavage studies from the same laboratory.Each of those studies established cholinergic LOELs at 10 mg/kg/day, but did not establishNOELs (Brooks and Broxup, 1995b and 1995c; Brooks et al., 1995). Further support came fromthe rat acute gavage study by Moser (2007) which established LED10s (ED10) of 1.1 (1.5) mg/kgbased on brain cholinesterase inhibition and 0.78 (1.11) mg/kg based on RBC cholinesteraseinhibition in postnatal day 11 animals, and from the acute inhalation toxicity study of Weinberg(2008), which established an LED10 (ED10) based on brain cholinesterase inhibition that wasequivalent to an internal dose of 0.66 (1.59) mg/kg, about halfway between the critical acuteNOEL of 1 mg/kg and the LED10 of 0.25 mg/kg..

The major uncertainty lay in the distinct possibility that cholinergic signs - particularly slighthypotonic gait, but possibly also slight tremors - were also present at 1 mg/kg, making that dosea LOEL rather than a NOEL. The uncertainties surrounding a LOEL determination at 1 mg/kgare discussed in the following paragraphs.

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LED10 = 0.25 mg/kg. Acutely induced slight hypotonic gait occurring in the course of FOBtesting in pregnant rats at 1 mg/kg (Robinson and Broxup, 1997) was the basis for the criticalacute oral LED10 determination of 0.25 mg/kg for carbaryl. There were several uncertaintiesassociated with this determination:

1. In six FOB tests conducted during gestation and five conducted within 21 days of theend of gestation, statistical significance with respect to controls was achieved only onceat 1 mg/kg (gd 12; p<0.05) and once at 10 mg/kg (gd 18; p<0.01). In fact, the statisticalsignificance observed at 1 mg/kg on gd 12 was not supported by an equivalentstatistically significant response at 10 mg/kg on the same day. The low level of statisticalverification of the effect accentuated the possibility that slight hypotonic gait was not aresponse to carbaryl exposure, at least at 1 mg/kg. However, examination of the dose-response curve in Figure 1 conflicts with this scenario, as does the dose responsivenessevident when the data were averaged over the entire gestation period (Table IV-1, whichis represented, in effect, by the line in Figure 1).

2. An effect of dosing on slight hypotonic gait may not have appeared until gd 9 (i.e., afterfour applications) or gd 12, when a statistically significant increase was noted at 1mg/kg. No effect was discernable at 1 mg/kg on gd 6. Thus the timing of the slighthypotonic gait effect might not be consistent with a classically acute response, if definedas occurring as a result of a single dose. However, as explained above in the HazardIdentification section (IV.A.1.a.), carbaryl’s propensity for clearance from the rat systemin less than 24 hours (Struble, 1994) combined with its relatively fast decoupling from thecholinesterase enzyme were considered strong evidence that each FOB test comprisedan independent acute assay of carbaryl’s neurotoxic effects.

3. Most of the FOB parameters appearing in Table III-15a were classified by theinvestigators as “slight” responses (“slight hypotonic gait”, “slight ataxic gait”, “slighttremors”). This emphasized the subjectivity of the data, since a judgment of "slight" inthe hands of one observer either may not have sufficed for a notification or beenclassified as moderate in the eyes of another evaluator.

4. The most scientifically credible route toward establishing an acute regulatory value usingthe incidence data for slight hypotonic gait was to model those data using the BMDapproach. This avoided the pitfalls associated with setting LOEL and NOEL values,allowing more of the data set to be used to determine the critical value. However, therewere uncertainties inherent in the BMD approach. First, there was uncertaintyassociated with chosen benchmark response level of 10%, since it was not known ifslight hypotonic gait comprised a centrally or peripherally-based response. If centrally-based, for example, the risk represented by slight hypotonic gait might be bettercharacterized by a benchmark response level of 5% rather than 10%, which isassociated with milder effects. Second, the decision to delete the top dose, which wasmade in order to generate a curve of appropriate fit and an LED10 value of lower than 1mg/kg (a dose that almost certainly generated effects), added uncertainty since itignored actual data gathered in the experiment. Third, the choice of the probit functionover other algorithms added uncertainty because each algorithm generated differentLED10 and ED10 values. And fourth, the decision to model the data using normalizedmean incidence rates, which was a consequence of considering all of the FOB tests tobe acute in nature, added uncertainty because it implied that data from single test days

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represented fluctuations around a mean. While this was considered the more likelyscenario, it remained possible that it underestimated the sensitivity of the system.

Uncertainty was also introduced into the critical study and the support studies with the gavageapproach, as food intake over a single "eating occasion" was likely to result in more gradualpesticide exposure than would occur after gavage. Depending on the pharmacokinetics ofcarbaryl toxicity, in particular whether acute toxicity is most influenced by the highest achievedconcentration or the total concentration over a finite time span (i.e., the area under the time-vs.-concentration curve), gavage dosing may generate a more severe response than acute dietaryexposure. Also, decarbamylation of impacted cholinesterases may be more prominent underdietary, as opposed to gavage, exposure scenarios, due to the more gradual pesticide-enzymeinteraction. Reactivation of cholinesterases over the exposure period would act to lessen thedietary response.

b. Chronic oral toxicityThe critical chronic oral LED10 of 0.5 mg/kg/day was based on inhibition of brain ChE activityafter 1 year of exposure in dogs at a low dose of 3.4 mg/kg/day (actually, 3.7 mg/kg/day infemales and 3.4 mg/kg/day in males; Hamada [1987]). The absence of both clinical signs andhistopathology throughout the study, even at the high dose of 34 mg/kg/day, leaves open thepossibility that the LED10 value was too low, since the enzyme inhibition was independent ofovert toxicity. This uncertainty was offset by two considerations, however. First, the absence ofovert toxicity does not necessarily signal a complete absence of toxicity, as subtle effects onlearning or memory were not addressed. And second, brain ChE suppression is considered byDPR to be an adverse effect in and of itself because it is mechanistically tied to cholinergictoxicity (DPR [2002b]).

It is noted that the critical chronic oral LED10 (0.5 mg/kg/day) was higher than the critical acuteoral LED10 (0.25 mg/kg), which may be considered unusual. However, this situation is not likelyto compromise human health; protection against untoward acute effects at lower dose levelswould ensure protection against chronic effects, regardless of their nature, resulting fromexposure at higher doses.

c. Reproductive and developmental toxicityEpidemiologic and laboratory animal data suggest that carbaryl may have adverse reproductiveand/or developmental impacts. The following points may be made concerning the epidemiologicstudies:

1. The relative risk for miscarriage approximately doubled in a cohort ofagricultural workers when carbaryl usage by males was combined with one oftwo other exposure categories, including “crop herbicide application” and“application of crop insecticides and fungicides” (Savitz et al. [1997]).

2. Wyrobek et al. (1981) failed to establish “a definitive link between carbarylexposure and human seminal defects” among workers and ex-workers in acarbaryl production facility. However, their data were suggestive of an increase inoligospermia (sperm count <20x106/ml) and teratospermia (>60% abnormalsperm forms) in that population.

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3. Sperm toxicity among workers in a carbaryl production facility was evidentin a recent study from China (Xia et al. [2005]). This was noted through theincreased morphologic abnormalities, disomic and nullisomic sperm and percentages of sperm with fragmented DNA,

4. Meeker et al (2004a and 2004b) demonstrated a positive correspondencebetween urinary levels of 1-naphthol, a primary carbaryl metabolite, and variousindicators of sperm toxicity among males seeking diagnoses in an infertility clinic.

The epidemiologic studies did not, however, make unambiguous associations between effectsand specific xenobiotic exposures. The extent of carbaryl exposure, both with regard to timespan and dose, was ill-defined and did not exclude the possibility of exposure to other riskfactors. Where carbaryl exposure was suggested by the presence of a urinary metabolite, thepossibility remained that the metabolite was generated from another xenobiotic - thus thestudies of Meeker et al. (2004a and 2004b) did not unambiguously attribute the presence of 1-naphthol in the urine of subfertile males to carbaryl exposure, especially as that metabolite canalso be generated from exposure to naphthalene. The study of Wyrobek et al. (1981), whichsuggested that oligospermia may be increased in carbaryl factory workers, was carried outusing low subject numbers. Possibly as a consequence, the measured effects showed lowstatistical confidence (though it might be argued that low statistical confidence in a small studyshould tilt the interpretation toward a positive association). However, a more recent examinationof carbaryl factory workers from China also provided evidence for sperm toxicity (Xia et al.[2005]). In reporting the increase in relative risk for miscarriage in wives of husbands workingwith carbaryl in agricultural settings, Savitz et al. (1997) also could not exclude a role for otherchemical and environmental stressors. Taken as a whole, the epidemiologic studies suggestedpotential reproductive problems in exposed males, though the data were considered supportiveas opposed to conclusive.

Reproductive and developmental toxicity concerns were also raised in laboratory animalstudies, as noted here:

1. In the most recent and most complete gavage studies to date, Pant et al.(1995, 1996) demonstrated impacts on testicular enzymes, sperm counts, spermmotility, sperm morphology and testicular morphology in rats at a daily carbaryldose of 50 mg/kg/day (5 days/week, 90 days).

2. Chronic administration of carbaryl to rats suggested adverse impacts onsperm motility, seminiferous tubule morphology, estrus cycle lengths,gonadotropic hormone levels and corpora lutea / atretic follicle numbers at dosesas low as 7 mg/kg/day (Shtenberg and Rybakova [1968]).

3. Collins et al. (1971) demonstrated impairments in several reproductiveindices in gerbils, including fertility, pups per litter, liveborn pups per litter, pupsurvival to days 4 and 21, and weanling weights at doses as low as ~160mg/kg/day.

4. Smalley et al. (1968) demonstrated severe dystocia and otherreproductive effects in pregnant beagle dogs after dietary exposure of themothers to carbaryl at doses as low as 3.125 mg/kg/day and developmental

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effects in their offspring at 6.25 mg/kg/day. In addition, Immings et al. (1969),also working with pregnant beagles, showed an increase in stillbirths at as low as2 mg/kg/day and an increase in post partum pup deaths at 5 mg/kg/day. Thesestudies are discussed below.

5. In a small gavage study in rats, Kitagawa et al. (1977) providedhistological evidence for decreases in spermatogonia and spermatozoa numbersin the seminiferous tubules during a 1-year gavage study at an approximate doseof 15 mg/kg/week.

As was the case for the epidemiologic studies, there were caveats in regards to the laboratoryanimal studies. In particular, the means of oral exposure (gavage bolus vs. dietary) may have abearing, at least in the rat, where bolus dosing was often used. Bolus exposures result in moreimmediate and higher blood levels of a test article than dietary exposure. A guideline rat dietaryreproductive toxicity study did not reveal carbaryl-induced effects on F0 or F1 reproductiveindices, parental epididymal sperm counts, sperm motility / morphology, homogenization-resistant spermatid head counts, daily sperm production or efficiency of daily sperm production(Tyl et al., 2001). There were, however, deleterious effects on pup body weights and survival, aswell as delays in developmental parameters. A dietary study in gerbils showed impairments inseveral reproductive indices, including fertility, pups per litter, liveborn pups per litter, pupsurvival to days 4 and 21, and weanling weights (Collins et al., 1971), though the relevance ofthe gerbil system in a risk assessment framework was not clear since this species is rarelyexamined. Several open literature gavage studies (Rybokova, 1966; Shtenberg and Rybakova,1968; Kitagawa et al., 1977; Pant et al., 1995, 1996) suggested histotoxicity in the malereproductive system of the rat, though standard reproductive indices were not measured. In arat gavage study, Dikshith et al. (1976) observed no significant effects on the rate of pregnancy,litter size, number of offspring born, or on pup health and viability through 10 days after exposedmales were mated with unexposed females, though carbaryl-induced changes in two testicularenzymes, succinic dehydrogenase and adenosine triphosphatase, were identified. Osterloh etal. (1983) did not observe effects on testicular parameters after intraperitoneal injections of malemice were carried out over a 5-day period. It was not clear if the negative result in this case wasdue to species insensitivity, an ineffective exposure route or other unknown factors.

As noted above, two older dog studies (Smalley et al., 1968; Immings et al., 1969) showedreproductive and developmental toxicity at dose levels similar to those employed in the criticalacute oral study of Robinson and Broxup (1997). Protection provided by the critical acute NOELmay extend to these effects, though it is noted that the Immings study did not establish a NOELfor stillbirths. However, there were caveats in the dog studies regarding the clarity of the doseresponse and the applicability of the dog data to humans, which are delineated below:

(1) While both studies showed toxic effects of carbaryl in pregnant beagles andtheir offspring, neither produced dose response relations sufficiently convincingto set regulatory levels. For a more complete discussion of the dose responserelations and other issues arising in the dog reproductive studies, see sectionIV.A.1.c. above.

(2) Knaak and coworkers (Knaak et al., 1965, 1968; Knaak and Sullivan, 1967)concluded that carbaryl metabolism in dogs differs from that in rats and humans. Knaak considered that dogs, unlike the latter two species, do not liberate 1-

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naphthol for glucuronidation or sulfation. Dogs may also be unable to hydroxylatecarbaryl. If true, such characteristics could make it difficult for dogs to mountadequate detoxification reactions, making them more sensitive to carbaryl-induced toxicity (though Knaak concluded that dogs conjugate the molecule"directly" and excrete it relatively efficiently [Knaak and Sullivan, 1967]). Dogsalso appear to excrete a higher portion of the carbaryl dose in the fecal fractionthan rats.

If Knaak is correct, a dog-specific carbaryl risk would require that theunexcreted ligand was either toxic (as might obtain if more unmetabolizedcarbaryl or more bioactive metabolites were available) or that the dog isinherently more sensitive to carbaryl and its derivatives. Neither of thesepossibilities has been demonstrated.

(3) The length of exposure required to elicit the reproductive and developmentaleffects in dogs was unclear since exposures occured over the entire 2-month doggestation period in the Smalley study and continued through the pre-weaningperiod in the Immings study. As such, it was difficult to determine if the effectswere acute or subchronic in nature.

(4) Khera (1976) noted that, unlike other mammals, the dog sheds immaturediploid ova, which then undergo a period of maturation and reduction to haploidybefore being receptive to sperm. This could generate an altered reproductivesensitivity to xenobiotics in the dog, decreasing its relevancy as a model forpotential effects in the human. However, there is no evidence at this time tosupport such a claim regarding carbaryl's toxicity to dogs. Indeed, the dogsystem provided the critical chronic oral value (see section b. below), which wascertainly independent of purported effects on the chromosome content ofgametes.

(5) As open literature studies, there was no empirical assurance that the carbarylused for dosing did not contain impurities. However, this must be viewed ashypothetical, as the presence or absence of impurities in those studies was notreported. If indeed such toxicologically significant impurities exist, their propertiesare not known even 40+ years after the dog studies were carried out.

Even considering the possible caveats to the use of dog studies, data from rats, rabbits andmice showed some developmental impact, though probably not without accompanying maternaltoxicity. In a guideline-compliant rat study, Repetto-Larsay (1998) noted an increase in theoccurrence of fetal runts - defined as those with body weight #75% of control means -accompanied by delayed or absent ossification in newborns following maternal gavage at 30mg/kg/day. These were probably related to the suppressed maternal weight gains noted at thatdose. A guideline rabbit study also demonstrated a tendency toward low birth weights at thehigh dose of 150 mg/kg/day (Tyl et al. [1999]). Murray et al. (1979) noted a single incidence ofomphalocele in a newborn rabbit after gestational exposure of the mothers to 150 mg/kg/daycarbaryl by gavage. In view of the extremely low historical control rate from this laboratory (2cases from 338 litters) and the fact that incidence rose to six newborns spread over 4 litters at200 mg/kg/day, it was concluded that omphalocele was likely to be carbaryl induced.Bodyweight loss and diarrhea were notably present in mothers bearing offspring with

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omphalocele. In the same report, dietary exposure of pregnant mice to 1166 mg/kg/day led toreduced maternal weight gains and fetal growth and ossification delays.

d. GenotoxicityAs noted above in section IV.A.1.f., carbaryl showed positive responses in one of five genemutation studies, four of six chromosomal aberration studies and two of four DNA damagestudies reviewed. However, all of the relevant positive studies were performed in vitro. Thecarbaryl metabolites nitrosocarbaryl and %-naphthol may also be genotoxic, though again, thishas been indicated only in in vitro studies.

The positive genotoxicity tests may have significance in the context of a carbaryl riskassessment in view of the clear oncogenicity and possible reproductive and developmentaltoxicity of this compound.

2. OncogenicityComparison of the dose ranges for several carbaryl-induced tumors in mice and rats suggestedthat the induction of hemangiosarcomas plus hemangiomas (H+H) in male mice was the mostappropriate endpoint for oncogenic risk analysis. This was based on the tendency of the mousesystem to develop this tumor at relatively low carbaryl doses. Since it was clear that H+Hincreased in several organ systems, it was assumed that development of these vascular tumorsin all organ systems reflected the same biological process (McConnell et al. [1986]). Thisassumption, which allowed use of the combined organ system data for benchmark doseanalysis, had uncertainties, particularly as it was not known if carbaryl’s access to, or metabolichandling by, each organ was strictly equivalent. In this regard, examination of H+H incidence inthe male liver -0/66, 4/66, 5/69* and 7/68**; (*,**; p<0.05, 0.01, respectively) - supports theplausibility of a low dose effect and suggests that the liver could indeed have special sensitivity.In fact, a dose-response relation for H+H was not apparent in any other organ in which thesetumors appeared. Furthermore, if the incidence rate for total number of H+H neoplasms ratherthan the per-animal incidence rate is examined - 2/66, 9/66*, 13/69** and 18/68*** (*,**,***;p<0.05, 0.01, 0.0001, respectively) - low dose responsiveness is quite evident.

Low dose linearity was assumed in the H+H data modeling. The ability of carbaryl to induceH+H was extrapolated to zero dose after deleting the top dose, as discussed in section IV.A.2above. An assumption of linearity may be valid in cases in which genetic damage plays acausative role. In the present case, carbaryl was clastogenic in four of six structuralchromosome aberration tests and two of four DNA damage studies (though as noted in theprevious section, the relevant positive studies were conducted in vitro). However, there was nodirect evidence that carbaryl-induced H+H was caused by genotoxicity. Furthermore, a 6-monthstudy in p53 knockout mice suggested that carbaryl may not act through a p53-based process(Chuzel [1999]). Linearized kinetics were thus invoked without an assurance that theyrepresented an actual oncogenic process.

Omission of the high dose compromised one of the major attractions of the benchmark doseapproach, to wit, its ability to take into account all of the doses in the analysis. In the currentcase it might be argued that, with few animals analyzed and fewer still responding, high doseomission is questionable, especially as a small incidence “error” in any direction at the lowerdoses can severely alter the slope of the incidence curve (i.e., the calculated oncogenicpotency). Of greater concern, however, was the striking possibility that inclusion of the highdose would result in underestimation of the oncogenicity of this compound, since it lowers the

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slope of the incidence curve by a factor of nearly 10. In view of the clear evidence that the highdose exceeded the MTD, its inclusion in the potency calculation was considered to be unwise.

The assumption of low-dose linearity can be avoided by invoking a threshold and calculating aresultant MOE. Waddell (2006) provided strong evidence that threshold mechanisms areoperative for most carcinogens examined in the NTP database. If a NOEL of 1.5 mg/kg/day isestimated by dividing the oncogenic LOEL of 14.73 mg/kg/day (the lowest dose tested) by anuncertainty factor of 10, the oncogenic MOE for the most highly exposed population is 3958.While this might be regarded as a low risk because it is higher that 100, it should be noted thatoncogenic risk has rarely (if ever) been assessed in this way; consequently, a standard ofnegligible risk has not been established. USEPA’s guidance document on cancer riskassessment (USEPA, 2005b) states that “a no-observed-adverse-effect level (NOAEL)generally is not used for assessing carcinogenic response when one or more models can befitted to the data”, which is the case here. In any case, the present data do not provide directevidence for a threshold mechanism, leaving such calculations in the speculative realm.

There are major uncertainties inherent in extrapolating tumor data from rodents to humans. Onefacet of the species extrapolation problem that is particularly relevant to the current caseconcerns the relationship between spontaneous incidence and chemical inducibility forparticular tumors. Does a high spontaneous incidence rate translate to a high level of chemicalinducibility? And vice versa, would a low spontaneous rate be associated with a low level ofinducibility? It is recognized, for example, that Strain A mice, an effective experimental systemfor the induction of lung tumors by cigarette smoke, will form lung tumors spontaneously withage (cf. Rubin, 2001). In the case of hemangiosarcomas, Pegg and Short (2006) pointed tomuch higher spontaneous incidence rates among rats and mice than among humans, raisingthe question of whether humans would also manifest a lesser response to a hemangiosarcoma-inducing chemical like carbaryl. The human hemangiosarcoma incidence rate as reported in theNational Cancer Institute SEER database, was 0.21 new cases per 100,000 people (0.00021%)between 1996 and 2000, with the tumors occurring most commonly in skin structures from thehead and neck. By contrast, the spontaneous incidence rate for B6C3F1 mice in the NationalToxicology Program database was 5.4% in males and 2.7% in females (range: 0-12%). Therange in Wistar rats was 0-3.4%. In addition to skin, spontaneous rodent hemangiosarcomasare commonly detected in liver, spleen, bone marrow and lymph nodes. The tendency of mice(particularly male mice) to form hemangiosarcomas, both spontaneously and through chemicalinduction, was also illustrated in a two-year study of mice exposed to metam sodium in drinkingwater (Horner, 1994; DPR, 2005). While there are no specific data to support a contention thathumans are intrinsically less sensitive to hemangiosarcoma-inducing chemicals, the possibilityshould at least be acknowledged.

Finally, uncertainties in the oncogenic, reproductive and developmental risk analyses arise fromour lack of knowledge of the effects of carbaryl degradates on these processes. This isparticularly relevant in view of the fact that residues of the carbaryl degradate 1-naphthol havebeen detected in some food commodity samples.

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B. DIETARY EXPOSURE ASSESSMENT

Uncertainties in the dietary exposure assessment fall into three major categories: (1) parameteruncertainty, (2) model uncertainty, and (3) scenario uncertainty (Peterson et al., 2001).

1. Parameter uncertainty Sources of parameter uncertainty in the dietary exposure assessment included the degree of completeness of the food residue database, the representativeness of that database to real-world exposures, the use of surrogate data, and the possible presence of sampling or reportingerrors. Carbaryl residue estimates were based largely on PDP data, with resort to FDA and fieldtrial data on particular commodities when PDP data were unavailable. In general, PDP is thedatabase of choice for risk assessment because it is statistically designed for that purpose.Certainly with regard to the refinements represented by the Monte Carlo approach (including theuse of residue distributions, percent crop treated data and processing data), PDP data aredesirable, as they represent a statistically randomized approach, with samples "chosen close tothe time and point of consumption (i.e., distribution centers rather than farmgate)" (PDP, 2004).Furthermore, PDP aims its residue determinations at foods likely to be consumed by infants andchildren, which is advantageous because these are subpopulations particularly susceptible toeffects induced by dietary exposure.

Several commodities - including carrots, canned spinach, soybeans, beans(snap/succulent/canned), tomatoes, winter squash, sweet corn, corn syrup, wheat, wheat flour,sunflower oil (field trial), peanut butter, bottled watter, beef fat, beef liver and beef muscle -produced no detectable residues. This meant that, for the point estimate determination, LODvalues were used, thus adding uncertainty because the actual residue levels for thesecommodities could be anywhere between zero and the LOD. The distributional (Monte Carlo)approach was less problematic in this regard because non-blended commodity estimates werebased on an assumption that only a fraction of the non-detects were at the LOD, depending onthe percentage of the crop that was treated (PCT) (see discussion below).

Residue data from field trials were employed in the current assessment for olives, sunflower oiland sunflower seeds. Such studies were conducted to determine the highest residue level thatcan result from maximum legal use of the pesticide. Field trial applications did not reflect actualuse patterns; the resultant residue data were used only because other data sources wereunavailable. As such, they almost certainly represented overestimates of exposure from thosecommodities. Fortunately, none of these commodities emerged as major contributors in eitherthe point estimate or distributional analyses, having little influence on the reliability of the overallrisk estimates.

Surrogate crops were assigned when residue data from PDP, FDA or field trials were notavailable for commodities with tolerances. The commodity / surrogate pairs used in thisassessment were derived from the crop group categorizations in 40CFR; they are listed insection IV.B.5.d. and in Table IV-2. The use of surrogates added obvious uncertainties to theanalysis.

Uncertainties in the dietary exposure assessment also arose from the consumption datacontained in the 1994-1998 CSFII survey. There are several possible sources for this type ofuncertainty, including the representativeness of actual dietary consumption, reporting errors, orvariation in dietary habits during or after the consumption period. This was particularly evident

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for two subpopulations: females 13+/pregnant/not nursing and females 13+/nursing. There wereso few user days represented for these groups (140 and 80, respectively) that the resultantexposure and risk estimates were considered to be unreliable.

2. Model uncertainty The 95th and 99th user day percentiles were presented in this assessment as estimated high-endexposures when the single highest detected residue or LOD was used for commodities withtolerances (i.e., in the Tier 2 / deterministc estimate). Acute dietary exposures to carbaryl,calculated at those exposure levels using the Tier 2 estimates indicated a health concern evenat the 95th percentile, as MOEs for all subpopulations were below the health protectivestandard of 100. However, these values represent, at best, high upper bound estimates ofdietary risk.

Because the point estimate data suggested the presence of risk when Tier 2 assumptions weremade, a more refined distributional modeling approach (Tier 3 / Monte Carlo) was initiated. Forthis assessment, the 95th, 99th and 99.9th percentiles were used for this analysis. Residuedistribution and PCT information were incorporated for all commodities for which distributionaldata were available, resulting in the creation of a series of residue distribution files using PDP-based data. With a few exceptions made for commodities lacking residue data that weresurrogated because preliminary analysis indicated a probability of high contribution to theexposure profile, the remaining commodities retained their point estimate values. By virtue oftheir lower consumption, they did not make a substantial contribution to the total carbarylconsumption.

Tier 3 analysis generated MOEs less than 100 for three subpopulations at the 99.9th user daypercentile using 1 mg/kg as the critical toxicology value and for all subpopulations using 0.25mg/kg as the critical toxicology value. In the latter case, the only exception was females13+/nursing, for which the data were unreliable (see above). Several subpopulations, includingnon-hispanic black, non-hispaninc / non-white / non-black, all infants, non-nursing infants,children 1-2 yr and adults 50+ yr, registered sub-100 MOEs using the 0.25 mg/kg criticaltoxicology value even at the 99th percentile. All MOEs exceeded the health-protective target of100 at the 95th percentile using 0.25 mg/kg and at the 95th and 99th percentiles using 1 mg/kg.These calculations were, however, subject to a major uncertainty related to incompleteness ofthe residue data base. Despite the high number of RDFs (~70) - which functioned to lower theoverall exposure estimates because they resulted in the great majority of residues within a dataset to be set to zero or to the LOD (depending on the PCT) - residue levels for many highlyconsumed commodities were maintained at the point estimate levels assigned to them in theTier 2 analysis due to the absence of specific data. This resulted in a certain overestimate ofexposure, since most of the the 350 commodities included in the analysis were in this category.A rough sense of the extent of this overestimation is gained by assigning RDFs to allcommodities within a crop group, making virtually every commodity with a reasonable surrogatesubject to a residue distribution. Using this approach with the 0.25 mg/kg LED10, MOEs at the99.9th percentile were 59 for all infants (i.e., ~4-fold greater than the MOE of 14 reported inTable IV-5), 57 for nursing infants <1 yr (~2-fold greater), 59 for non-nursing infants <1 yr (~4-fold greater), 59 for children 1-2 yr (~4-fold greater) and 64 for children 3-5 yr (~3-fold greater).All other subpopulations showed 99.9th percentile MOEs greater than 100. For example, theMOE for the US population was 146, ~4-fold greater than the corresponding MOE in Table IV-5.All 99th and 95th percentile MOEs were well over 100.

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This exercise suggests that the exposure estimates at the 99.9th percentile could be as muchas 4-5-fold less than those reported here (with consequent MOEs 4-5-fold greater). Of coursethe exercise imposed its own uncertainties, since RDFs, including their attendant percent croptreated values, were applied as surrogates to commodities for which there were no data.However, it also emphasizes the seriousness of the risk imposed by dietary carbaryl, particularlyto infants and young children, as these subpopulations continued to register low MOEs evenwhen surrogate distributions were applied to virtually all commodities lacking specific data.

A similar uncertainty pertained to the chronic analysis, as surrogate high acute point estimateswere applied to commodities lacking specific data. This resulted in certain overestimation ofexposure and understimation of MOEs, since chronic residue values were the average ofresidue values determined in many samples (including a majority of non-detects, which were setat one-half of the LOD value). However, as no subpopulation registered a chronic MOE lowerthan 869 (non-nursing infants), this point serves only to further discount the potential for riskstemming from chronic exposure to carbaryl.

Finally, it is worth noting that the distributional files included several blended commodities. Assuch, the “distributions” for those commodities did not include any samples that were set tozero, since blending was considered to represent a mixture of treated and untreatedcommodities. Nonetheless, this probably resulted in overestimates of acute exposure, sincepotential "zero" or sub-LOD values were removed from the analysis.

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C. RISK CHARACTERIZATION

1. Non-oncogenic riskNon-oncogenic risk was evaluated by use of the margin of exposure ratio, equivalent to thecritical NOEL or LED divided by the anticipated exposure. A MOE of 100 or more is consideredsufficiently protective of human health when the NOEL of LED for an adverse effect is derivedfrom an animal study, as was the case in this assessment. The MOE of 100 assumes thathumans are 10 times more sensitive than the most sensitive laboratory animals and that there isa 10-fold variation in sensitivity within the human population. Uncertainties were introduced intothe MOE calculations by uncertainties in both the LED and exposure terms, and were recountedin detail in the preceding paragraphs.

The MOEs for acute dietary exposure were calculated using either of two critical toxicologicvalues: (1) a critical NOEL of 1 mg/kg based on cholinergic signs detected with FOB testingand decrements in body weight gain in pregnant rats at 10 mg/kg (Robinson and Broxup, 1997);or (2) a critical acute LED10 of 0.25 mg/kg, based on the induction of slight hypotonic gait at theLOEL dose of 1 mg/kg in pregnant rats in the same study (Robinson and Broxup, 1997). Theresidue exposure data were derived predominantly from the PDP database.

Tier 2 analysis using point estimates established at the highest residue level measured or, inthe case of no detections, at the high LOD, generated MOEs lower than 100 at both the 95th and99th user day percentiles with either critical toxicology value, triggering distributional (Tier 3)analyses in both cases. MOEs from Tier 3 analysis were above the health protective standard of100 at the 95th and 99th user day percentiles for all of the subpopulations analyzed when aNOEL of 1 mg/kg was used. However, three subpopulations fell under 100 at the 99.9th

percentile, indicating a potential acute risk. When 0.25 mg/kg was used, MOEs were lower than100 for several subpopulations at the 99th percentile and nearly all subpopulations at the 99.9th

percentile. To the extent that these values were based on an LED10 extrapolated from data in alaboratory animal study (see discussion in section V.A.1.a. in particular), they should beconsidered uncertain. The exposure terms were refined by Tier 3 distributional analyses, whichattempted to model the residue database in as "realistic" a manner as the data allowed throughthe Monte Carlo approach. However, the absence of residue data on many commodities mayhave resulted in as much as a 4-5-fold overestimation of total exposure, since these valueswere set at the highest residue value measured (see discussion above, section V.B.2.). Evenwith this consideration, Monte Carlo analysis generated MOEs less than 100 for severalsubpopulations at the 99.9th percentile.

The MOEs for chronic dietary exposure were calculated using (1) the critical chronic LED10 of0.5 mg/kg/day, based on inhibition of brain cholinesterase activity at 3.4 mg/kg/day and above indogs at 52 weeks (Hamada, 1987), and (2) mean exposure data derived mostly from the PDPdatabase. As these MOEs were uniformly high even without the incorporation of percent croptreated data (lowest MOE = 763), it was considered unlikely that chronic dietary exposurepresented an appreciable chronic health risk.

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2. Oncogenic riskOncogenic risk is expressed as the product of the projected exposure multiplied by the 95%upper bound on potency. The resultant unitless value represents the total extra cases expectedas a result of "lifetime" exposure to carbaryl. In the context of the DEEM-FCID®-based dietaryassessment, the amortized lifetime exposure is essentially the same as the chronic exposureoutput for the various adult subpopulations, which is why the range of oncogenic risk values,2.54x10-6 and 3.83x10-6, was calculated based on the average exposure indicated for thosegroups. Because they were more than the negligible risk standart 10-6, dietary consumption ofcarbaryl was considered to constitute an oncogenic risk.

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D. CRITICAL TOXICITY ENDPOINTS AND RISK CALCULATIONS - USEPA vs. DPR

USEPA outlined their endpoints for carbaryl in a Reregistration Eligibility Decision document(RED) dated September 2007 (USEPA, 2007a) and in a more specific chapter on toxicity datedJune 2007 (USEPA, 2007b). Their conclusions are summarized and compared to the valuesestablished in the present document in the following paragraphs and in Table V-1.

Acute oral toxicity. USEPA's acute "point of departure" (PoD) was 1.1 mg/kg, an LED10 valuederived from brain cholinesterase inhibition data in postnatal day 11 rats (Moser, 2007). TheUSEPA PoD was essentially equivalent to DPR's critical acute NOEL of 1 mg/kg, but ~4-foldgreater than DPR's critical acute LED10 of 0.25 mg/kg. Combined with DPR's more selective useof surrogate residue data files in the Tier 3 / Monte Carlo exposure analysis (see section V.B.2.above), these critical values largely account for the differences between the two agencies intheir estimation of risk. (DPR also used, wherever possible, only residue data collected inCalifornia.) USEPA concluded that dietary exposure to carbaryl was lower than their targetvalue of 100% of the "acute population adjusted dose" (aPAD) at the 99.9th user day percentilefor all subpopulations analyzed. For example, the aPAD was 29% for the US population(equivalent to a MOE of 345), 40% for all infants (equivalent to a MOE of 250) and 60% forchildren 1-2 yr (equivalent to a MOE of 167). Equivalent Tier 3 MOEs calculated by DPR forthose subpopulations at the 99.9th percentile were 164, 92 and 92 (NOEL = 1 mg/kg) and 41, 23and 23 (LED10 = 0.25 mg/kg). DPR thus anticipates a higher level of risk from dietary exposureto carbaryl, regardless of the critical acute toxicity term used to calculate MOEs.

Chronic oral toxicity. USEPA did not estimate a chronic PoD for carbaryl, as it did notconsider that carbaryl, with its rapid dissociation from the cholinesterase enzyme, posed achronic risk (USEPA, 2007b). DPR's chronic oral LED10 of 0.5 mg/kg/day (ED10 = 1.7 mg/kg/day)was derived using benchmark dose methodology applied to cholinesterase inhibition data in the1-year dog study of Hamada (1987). In any case, the lowest chronic MOE calculated by DPR,763 for children 1-2 yr, was considered to represent a negligible risk due to chronic dietaryexposure.

Oncogenicity. USEPA regards carbaryl as a "likely human carcinogen" (USEPA, 2007b).USEPA and DPR agreed that the formation of hemangiosarcomas in male mice, observed inthe 2-year study of Hamada (1993b), was the most sensitive oncogenic endpoint (though DPRincluded hemangiomas). The 95% upper bound human equivalent potency slope valuescalculated by the two agencies were not similar, however, differing by a factor of 11.5-fold(USEPA: 8.75x10-4 mg/kg/day-1; DPR: 1.01x10-2 mg/kg/day-1). The major source of thisdiscrepancy was almost certainly DPR's choice to eliminate the high dose in conducting thepotency analysis (see discussion in sections IV.A.2 and V.A.2). USEPA's consequent risk value,2.8x10-8 for the US population did not exceed the negligible risk standard of 10-6. DPR's range ofrisk values, 2.54x10-6 - 3.83x10-6 for the adult populations analyzed, clearly did exceed thatstandard.

Reproductive and developmental toxicity. USEPA did not discuss either of the dogreproductive / developmental studies that evidenced toxicity (Smalley et al., 1968; Immings etal., 1969), nor was the dog metabolism study of Knaak et al. (1967) considered. A 1976 USEPAmemo written by Dr. Neil Chernoff discounting the relevance of the dog data to humantoxicology was assumed to constitute USEPA's current position on this issue and probably

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underlaid their decision not to consider the dog studies in the RED (Chernoff [1976]). Dr.Chernoff's position is quoted below:

"I feel that with the exception of the dog, in cases where severe maternal toxicityhas not been observed there have been no consistent adverse reproductive orfetotoxic effects induced by carbaryl. The positive effects seen in the dog mustbe evaluated in light of its reported unusual metabolism. In the other specieswhere positive effects have been shown, these effects must be considered interms of maternal toxicity induced by the treatment, and the extremely high doselevels used. I feel that the use of such experiments which test for the maximumpotential of a compound to induce effects is necessary to indicate types of effectsto be looked for at lower dose levels (and such studies are regularly done in mylaboratory). I do not feel that such studies should be afforded importantconsideration in the overall toxicological evaluation of safety for the continueduse of carbaryl. I feel, therefore, that the evidence to date does not indicate thatcontinued use of carbaryl would pose a reproductive or fetotoxic threat to man."

In contrast to USEPA, this assessment treats the dog studies at some length, as it did notconsider the observed maternal, fetal and perinatal toxicity to be necessarily contravened by theavailable dog metabolism data.

In general, USEPA did not express a high level of concern about the potential for reproductiveor developmental toxicity, as the NOELs in the contract studies that they examined were higherthan the critical acute PoD of 1.1 mg/kg. Application of a Food Quality Protection Act safetyfactor of 1 reflected this view. DPR viewed reproductive toxicity mainly through the lens ofepidemiologic studies, which indicated potential reproductive problems in males. DPR alsoconsidered the developmental toxicity evident in the beagle study discussed above to reflect apotential developmental risk.

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Table V-1. Critical toxicity endpoints for carbaryl: USEPA vs. DPR

Study type USEPA RED (USEPA, 2007a & 2007b) DPR

Acute toxicity,regulator value#1

Moser, 2007Acute toxicity - ratLOEL value not determined (brain ChEI)

LED10 = 1.1 mg/kgRfD & aPAD a = 0.01 mg/kg

Robinson & Broxup, 1997Developmental ntx - rat

NOEL = 1 mg/kgRfD b = 0.01 mg/kg

Acute toxicity,regulator value#2

Moser, 2007Acute toxicity - ratLOEL value not determined (brain ChEI)

LED10 = 1.1 mg/kgRfD & aPAD a = 0.01 mg/kg

Robinson & Broxup, 1997Developmental ntx - ratLOEL value not determined (increased slighthypotonic gait)LED10 = 0.25 mg/kgRfD b = 0.0025 mg/kg

Chronic toxicity n/a (USEPA did not consider carbaryl to pose achronic toxicity risk)

Hamada, 19871-year chronic - dogLOEL = 3.1 mg/kg/day (brain / RBC / plasma ChEI)LED10 = 0.5 mg/kg/day

RfD 1 = 0.005 mg/kg

Oncogenicity Hamada, 1993b2-year chronic / onco - mouseDose-dependent hemangiosarcomas

95% UB potency = 8.75x10-4

Hamada, 1993b2-year chronic / onco - mouseDose-dependent hemangiosarcomas / hemangiomas95% UB potency = 1.01x10-2

a Abbreviations: RfD, reference dose; aPAD, acute population adjusted dose. In the case of USEPA'scarbaryl RED, the aPAD and RfD are equivalent (i.e., both 1/100 of the acute LED10).b DPR reference doses are calculated in section VII.

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VI. ISSUES RELATED TO THE FOOD QUALITY PROTECTION ACT

The Food Quality Protection Act of 1996 mandated the USEPA to “upgrade its risk assessmentprocess as part of the tolerance setting procedures” (USEPA [1997a and b]). The improvementsto risk assessment were based on recommendations made in the 1993 National Academy ofSciences report, “Pesticides in the Diets of Infants and Children” (NAS [1993]). The Act requiredan explicit finding that tolerances are safe for children. USEPA was required to use an extra 10-fold safety factor to take into account potential pre- and post-natal developmental toxicity andthe completeness of the data, unless USEPA determined, based on reliable data, that adifferent margin would be safe. In addition, the USEPA must consider available information on:1) aggregate exposure from all non-occupational sources; 2) effects of cumulative exposure tothe pesticide and other substances with common mechanisms of toxicity; 3) the effects of inutero exposure; and 4) the potential for endocrine disrupting effects.

Aggregate exposure. Only a single route of exposure, oral, was considered for this document.Aggregate exposure (i.e., exposure to a chemical by various routes) will be assessed at a laterdate when exposure estimates from other routes become available.

Cumulative exposure. USEPA is currently evaluating the potential for cumulative exposure toN-methyl carbamate pesticides. We will await the outcome of that evaluation before rendering ajudgement on cumulative risk.

In utero effects. Several lines of evidence suggest that carbaryl may have developmentaleffects: (1) epidemiologic studies in human populations have associated carbaryl exposure withsperm deficits or disorders (Savitz et al. [1997]; Wyrobek et al. [1981]; Xia et al. [2005]; Meekeret al. [2004a and 2004b]); (2) two older dog studies demonstrated developmental impacts whenfetuses were exposed through the maternal diet (Smalley et al. [1968]; Immings et al. [1969]); (3) several animal studies evidenced direct carbaryl effects on sperm and/or spermatogenictissue (Rybakova [1966]; Shtenberg and Rybakova [1968]; Pant et al. [1995, 1996]; Kitagawa etal. [1977]; (4) several in vitro genotoxicity studies showed positive effects of carbaryl; and (5) aguideline rat reproductive study showed increased pup mortality, reduced body weights anddelayed developmental indices at 1500 ppm (92-136 mg/kg/day) and increased F2 mortality, pnd0-4, at 300 (5-6 mg/kg/day) and 1500 ppm (Tyl et al. [2001]). However, the relevance of thedog system to humans has been questioned in regard to the fetal and developmental effects(see discussions in sections III.G.2.c., IV.A.1.a, V.A.1.a, V.A.1.c., V.A.1.d. and V.D.). Neither ofthe guideline developmental toxicity studies (Tyl et al. [1999], in rabbits; Repetto-Larsay [1998],in rats), showed developmental effects of this nature in rats or rabbits, though the issue ofspermatogenic defects was not specifically addressed. Finally, no direct evidence of birthdefects has been reported in human populations, despite many years of carbaryl usage. In viewof these competing considerations, this assessment does not make a recommendationregarding reproductive or developmental toxicity. At the very least, this will await the submissionof more contemporary studies in the dog system.

Endocrine effects. The mechanisms by which carbaryl disrupts canine pregnancies or inducestesticular toxicity are unknown, though it remains possible that endocrine pathways areinvolved. Nonetheless, the extent of endocrine involvement, if any, in such effects should beapproached with specifically designed studies.

VII. REFERENCE DOSES (RfDs)

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Oral doses of carbaryl below a calculated reference dose (RfD) were considered unlikely topose a risk to human health. RfDs were calculated for acute and chronic dietary exposurescenarios by dividing the critical oral NOELs by an uncertainty factor of 100. All of theuncertainties that accompanied selection of this endpoint were applicable to this calculation(see section V.A.). Potential exposures sustained under occupational scenarios, either by thedermal or inhalation routes, were outside the scope of this analysis. The RfDs calculated belowwere most relevant to the general population exposed through the diet. Two such values werecalculated for acute oral exposure, reflecting the critical acute NOEL of 1 mg/kg and the criticalacute LED10 of 0.25 mg/kg.

1. Critical acute NOEL = 1 mg/kg

RfD = critical acute NOEL ÷ 100critical acute oral NOEL = 1 mg/kg

RfDacute = 1 mg/kg ÷ 100 = 0.01 mg/kg

2. Critical acute LED10 = 0.25 mg/kg

RfD = critical acute LED10 ÷ 100critical acute oral LED10 = 0.25 mg/kg

RfDacute = 0.25 mg/kg ÷ 100 = 0.0025 mg/kg

3. Critical chronic oral NOEL = 0.5 mg/kg/day

RfD = critical chronic oral NOEL ÷ 100critical chronic oral NOEL = 0.5 mg/kg/day

RfDchronic = 0.5 mg/kg/day ÷ 100 = 0.005 mg/kg/day

In Table VII-1, the calculated oral RfDs for carbaryl are compared with the anticipated dietaryexposure ranges for the various subpopulations. If the RfDacute is established using the criticalacute NOEL of 1 mg/kg (RfDacute = 0.01 mg/kg), acute dietary exposures calculated using thepoint estimate approach at the 95th percentile exceeded the RfDacute for all infants, nursinginfants <1 yr, non-nursing infants <1 yr, children 1-2 yr and children 3-5 yr. Using the MonteCarlo approach at the 99.9th percentile, the RfDacute was exceeded for all infants, non-nursinginfants <1 yr and children 1-2 yr. If, on the other hand, the RfDacute is established using thecritical acute LED10 of 0.25 mg/kg (RfDacute = 0.0025 mg/kg), acute dietary exposures calculatedusing both the point estimate approach at the 95th percentile and the Monte Carlo approach atthe 99.9th percentile exceeded the RfDacute for all of the subpopulations yielding sufficient userday data (see footnote to Table VII-7). Thus the exposure data combined with RfDacute valuesuggest that exposure mitigation for acute effects should be considered.

By contrast, the highest chronic dietary exposure estimate, which was recorded for non-nursinginfants <yr, was only 12% of the RFDchronic. By this measure, chronic exposure to carbaryl doesnot pose a non-oncogenic risk to any sub-population and does not currently warrant mitigation.

Table VII-1. Oral reference doses (RfDs) and anticipated dietary exposures to carbaryl

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Exposure time andspecies

Endpoint LOEL and NOEL(or LED)

RfD Anticipated exposures

Acute NOELrat gavage dvpmt.ntx. study, gd 6 -ppd 10 (Robinson& Broxup, 1997)

cholinergicsigns and bodyweight gaindecrements

LOEL10 mg/kg

NOEL1 mg/kg

0.01 mg/kgdietary, 95thpercentile, Tier 2 (PE) b

0.004087 - 0.014953mg/kg/day

dietary, 99.9thpercentile, Tier 3(MC)b

0.003564 - 0.012796mg/kg/day

Acute LED10rat gavage dvpmt.ntx. study, gd 6 -ppd 10 (Robinson& Broxup, 1997)

slight hypotonicgait

LOELnot determined a

LED100.25 mg/kg

0.0025 mg/kgdietary, 95thpercentile, Tier 2 (PE) b

0.004087 - 0.014953mg/kg/day

dietary, 99.9thpercentile, Tier 3(MC)b

0.003564 - 0.012796mg/kg/day

Chronic NOELdog 1-yr dietarystudy (Hamada,1987)

brain ChEI LOEL3.4 mg/kg/day

LED100.5 mg/kg/day

0.005 mg/kg/daydietary (chronic) b

0.000225 - 0.000655mg/kg/day

a An appearance of slight hypotonic gait at 10 mg/kg was certain, though less certain at 1 mg/kg. As aconsequence, these data were subjected to benchmark dose analysis.b PE, point estimate; MC, Monte Carlo estimate. The dietary subpopulations examined are those coveredin the DEEM-FCID® dietary analysis. The dietary exposure values were taken from Tables IV-3 and IV-4.Two subpopulations - females 13+ pregnant / not nursing and females 13+ nursing - were excluded fromthis comparison due to an insufficient number of available user days for analysis.

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VIII. TOLERANCE ASSESSMENT

A tolerance is the legal maximum residue concentration of a pesticide, which may be present inor on a raw agricultural commodity or processed food. USEPA is reponsible under the FederalFood, Drug and Cosmetic Act (FFDCA) for setting tolerances for pesticide residues (Section408). The tolerances are established at levels necessary for the maximum application rate andfrequency, and are not expected to produce deleterious health effects in humans from chronicdietary exposure (USEPA, 1991).

The data requirements for the registration of pesticides and for establishment of tolerancesinclude: (1) residue chemistry (including measured residue levels from field studies), (2)environmental fate, (3) toxicology, (4) product performance (i.e., efficacy), and (5) productchemistry. The field studies must reflect the proposed uses with respect to the rate and mode ofapplication, the number and timing of applications and the proposed formulations (USEPA,1982).

In 1996, the Food Quality Protection Act (FQPA) amended the overall regulation of pesticideresidues under FIFRA and FFDCA (USEPA, 1997a). Significantly, the Delaney Clause, whichprohibited residues of cancer-causing pesticides in processed foods, was removed. However,FQPA requires scientific evidence showing that tolerances are safe for infants and children.USEPA must consider applying an additional safety factor of up to 10 to take into accountpotential pre- and post-natal developmental toxicity and completeness of the database.

FQPA also requires USEPA to reassess existing tolerances and tolerance exemptions for activeand inert ingredients by 2006 (USEPA, 1997b). Tolerance reassessments had previously beenexecuted as part of USEPA’s re-registration and Special Review processes. All label-usecommodities are evaluated using a tiered approach similar to that used for the general dietaryassessments.

In California, Assembly Bill 2161 (The Food Safety Act) requires DPR to “conduct anassessment of dietary risks associated with the consumption of produce and processed foodtreated with pesticides” (Bronzan and Jones [1989]). In situations whereby “any pesticiderepresents a dietary risk that is deleterious to health of humans, the DPR shall prohibit or takeaction to modify that use or modify the tolerance”.

A. ACUTE EXPOSUREAn acute tolerance assessment was conducted for each “high-contributor” commodity, definedfor this assessment as those commodities providing greater than 5% of the total carbarylconsumption as indicated by the Critical Exposure Contribution analysis for infants and children1-2 yr using the DEEM-FCID® Tier 2 / point estimate approach. These commodities includedblueberries, peaches, asparagus, apricots, blackberries and apples. The consumption databasecame from the USDA Continuing Survey of Food Intakes of Individuals 1994-1998 (CSFII). Theacute tolerance assessment did not address simultaneous consumption of multiple commoditiesat tolerance levels. The probability of consuming multiple commodities at such levelssignificantly decreases as the number of commodities included in the assessment increases.Consumption of even two commodities at tolerance was considered unlikely (and in any case,the MOEs were below 100 for single commodities; see below).

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The exposure levels and MOE values at the 95th exposure percentile for each analyzedcommodity is shown in Table VIII-1. It should be noted that the consumption patterns for a givensubpopulation is better represented when the survey sample size is sufficiently large (i.e., >100user days). Data from subgroup-commodity pairs with less than this amount were considered tobe unreliable. Despite this caveat, MOEs of less than 100 were indicated for every commodityexamined when there were sufficient user days available for analysis, regardless of whether 1mg/kg or 0.25 mg/kg was used as the toxicology term. Thus carbaryl tolerances should bereevaluated, as residues at the current tolerance levels result in inadequate MOEs. The dataare summarized in Table VIII-1.

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Table VIII-1. Acute dietary margins of exposure for high contributing commodities (>5%) at thecarbaryl tolerance level; 95th percentile user days

Commodity and tolerance a

Population subgroup Blueberry10 ppm

Peach 10 ppm

Asparagus15 ppm

Apricot10 ppm

Blackberry10 ppm

Apple12 ppm

1. US population MOE (95th percentile) exposure (mg/kg) unweighted user days

304 / 76.00328610472

40 / 10.02323811921

12 / 3.063893239

116 / 29.0084794723

484 / 121.0020493944

4 / 1.14885917358

2. Western region MOE (95th percentile) exposure (mg/kg) unweighted user days

336 / 84.0029432410

36 / 9.0251622854

20 / 5.04747065

84 / 21.0115971274

420 / 105.0023681055

4 / 1.1504414064

3. Hispanics MOE (95th percentile) exposure (mg/kg) unweighted user days

490 / 124.0020131051

32 / 8.0309791282

20 / 5.0476189

140 / 35.006945520

664 / 166.001503438

4 / 1.1872832066

4. Non-hispanic whites MOE (95th percentile) exposure (mg/kg) unweighted user days

268 / 67.0037277766

44 / 11.0225558687

12 / 3.064136214

92 / 23.0105753232

416 / 104.0023892630

4 / 1.14125312124

5. Non-hispanic blacks MOE (95th percentile) exposure (mg/kg) unweighted user days

492 / 123.0020221243

44 / 11.0217271458

4 / 1.2099387

688 / 172.001453772

1464 /366.000683713

4 / 1.1566322350

6. Non-hispanic / non- white /non-black MOE (95th percentile) exposure (mg/kg) unweighted user days

272 / 68.003640412

48 / 12.019714494

32 / 8.0294749

88 / 22.011033199

832 / 208.001198163

4 / 1.172082818

7. All infants MOE (95th percentile) exposure (mg/kg) unweighted user days

28 / 7.035386202

4 / 1.155827439

4 / 1.1487013

8 / 2.086223197

36 / 9.02641446

2 / 0.4291681149

8. Nursing infants <1 yr MOE exposure (mg/kg) unweighted user days

20 / 5.04688744

4 / 1.15554388

noexposure

12 / 3.06853338

48 / 12.02000313

0.379791213

9. Non-nursing infants <1 yr MOE (95th percentile) exposure (mg/kg) unweighted user days

28 / 7.033858158

4 / 1.155261351

4 / 1.1487013

8 / 2.092135156

36 / 9.02640233

2 / 0.430391936

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10. Females 13+ (preg./notlact.) MOE (95th percentile) exposure (mg/kg) unweighted user days

448 / 112.00222433

32 / 8.03018735

noexposure

48 / 12.01962510

256 / 64.0038738

4 / 1.13064148

11. Females 13+ (lactating) MOE (95th percentile) exposure (mg/kg) unweighted user days

696 / 174.00142922

56 / 14.01731122

noexposure

56 / 14.0170028

972 / 243.0010256

12 / 3.06499436

12. Children 1-2 yr MOE (95th percentile) exposure (mg/kg) unweighted user days

160 / 40.0062471241

8 / 2.0866121420

4 / 1.18756219

24 / 6.036493552

324 / 81.003085445

2 / 0.4366982655

13. Children 3-5 yr MOE (95th percentile) exposure (mg/kg) unweighted user days

180 / 45.0054623103

20 / 5.0480393311

4 / 1.14806523

128 / 32.0077351529

404 / 101.0024721391

3 / 0.2944085347

14. Children 6-12 yr MOE (95th percentile) exposure (mg/kg) unweighted user days

280 / 70.0035591470

36 / 9.0250991541

4 / 1.20948513

216 / 54.004557716

516 / 129.001931671

4 / 1.1336442112

15. Youth 13-19 yr MOE (95th percentile) exposure (mg/kg) unweighted user days

404 / 101.002453584

56 / 14.017622593

20 / 5.0437374

332 / 83.002987281

596 / 149.001671256

8 / 2.085884731

16. Adults 20-49 yr MOE (95th percentile) exposure (mg/kg) unweighted user days

344 / 86.0028751841

52 / 13.0180961920

12 / 3.06887459

144 / 36.006894621

564 / 141.001771497

16 / 4.0544402372

17. Adults 50+ yr MOE (95th percentile) exposure (mg/kg) unweighted user days

384 / 96.0025892031

52 / 13.0181062697

16 / 4.053899118

88 / 22.010982830

552 / 138.001809638

20 / 5.0455792992

18. Females 13-49 yr MOE (95th percentile) exposure (mg/kg) unweighted user days

348 / 87.0028651245

48 / 12.0201261340

12 / 3.06868229

200 / 50.004984501

648 / 162.001536409

16 / 4.0622561634

19. Males/Females 16-70 yr MOE (95th percentile) exposure (mg/kg) unweighted user days

344 / 86.0028833588

56 / 14.0173604064

16 / 4.058082137

160 / 40.0062311307

504 / 126.0019821058

16 / 4.0528754810

Note: An acute tolerance assessment was conducted for carbaryl residues on each commodity whichregistered higher than 5% dietary contribution in the Tier II DEEM-FCID® point estimate for infants and forchildren 1-2 yr. The carbaryl residue level for each commodity was set at the tolerance. The DEEM-FCID®

program was used with the following input parameters: (1) USDA CSFII 1994-1998, and (2) an acute

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NOEL of 1 mg/kg or an acute LED10 0.25 mg/kg. The first value in the top line of each box represents theMOE calculated with the 1 mg/kg NOEL, the second with the 0.25 mg/kg LED10. The precise MOE maydiffer slightly from the quotient of the NOEL (or LED) ÷ exposure dose due to rounding. This may beaccented with the 1 mg/kg MOE because it was calculated by multiplying the DEEM-derived 0.25 mg/kgMOE by 4. The acute dietary exposure was calculated at the 95th percentile of user days for all of thepopulation subgroups examined in the dietary assessment.a Tolerances were listed in the Federal Register, Vol. 73, No. 176, Sept. 10, 2008.

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B. CHRONIC EXPOSUREA chronic exposure assessment using residue levels set to the established carbaryl toleranceswas not attempted. It was highly improbable that single or multiple commodities containingpesticide levels at tolerance would be consumed habitually. This conclusion was supported bydata from both the federal and DPR pesticide monitoring programs which indicated that only aminute fraction of all sampled commodities contained residue levels at or above the establishedtolerance.

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IX. CONCLUSIONS

A dietary risk characterization was carried out for the insecticide carbaryl. It includes a completetoxicity profile and summaries of carbaryl's environmental fate, current uses and illness / injuryreports for the years 1992-2007, in addition to a dietary exposure assessment and riskcharacterization for 19 different human subpopulations. Laboratory investigations indicated apotential for toxicity under various exposure routes and times of exposure, including some thatindicate that carbaryl is oncogenic. The document also reviews several laboratory andepidemiologic studies that suggest that carbaryl may have adverse impacts on reproductionand/or development. Acute and chronic dietary exposure scenarios were considered for the riskcharacterization aspect of this document. Because the critical LED10s were based on laboratoryanimal studies, a margin of exposure (MOE) of 100 was considered sufficiently protective ofhuman health.

Critical NOELs, LEDs and cancer potency values. The following values, based on laboratoryanimal studies, were established for carbaryl (including two acute oral values from the samestudy representing endpoints of stronger or weaker experimental support):

‚ Acute oral NOEL: 1 mg/kg - based on the appearance of cholinergic signs detectedin FOB testing (slight tremors, slight hypotonic gait, slight ataxic gait and pinpoint pupils) andbody weight gain decrements at 10 mg/kg.

‚ Acute oral LED10: 0.25 mg/kg - based on induction of slight hypotonic gait in a ratgavage study over the dose range of 0.1 - 10 mg/kg.

‚ Chronic oral LED10: 0.5 mg/kg/day - based on inhibition of brain cholinesteraseactivity in a 1-yr dog dietary study.

‚ Human equivalent cancer potency value: 1.01x10-2 mg/kg/day-1 (the 95% upperbound estimate) and 4.29x10-4 mg/kg/day-1 (maximum likelihood estimate) - based onhemangiosarcomas and hemangiomas in both sexes in a mouse two-year feeding study.

‚ Reproductive and developmental toxicity: Evidence originating in non-guidelinestudies, both of an epidemiologic and laboratory animal nature, suggested the possibility thatcarbaryl could have reproductive and/or developmental impacts. However, based on insufficientdata, this assessment does not present a risk evaluation regarding reproductive ordevelopmental toxicity.

Dietary risk characterization. A dietary exposure and risk evaluation was conducted for 19subpopulations, and included all commodities for which carbaryl tolerances exist, in addition todrinking water.

‚ Acute toxicity (NOEL = 1 mg/kg): Margins of exposure (MOEs) based on the highestresidue determination for each commodity (Tier 2) were below the health protective standard of100 for several subpopulations at the 95th user day percentile. At the 99th user day percentile,most populations showed MOEs less than 100, reaching as low as 24 for all infants and non-nursing infants <1 yr. A refined Tier 3 / Monte Carlo analysis was triggered because of theselow values.

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There were no subpopulations exhibiting MOEs below 100 at the 95 or 99th user daypercentiles using Monte Carlo analysis (Tier 3). However, at the 99.9th percentile, threesubpopulations exhibited MOEs below 100: all infants (MOE=91), non-nursing infants <1 yr(MOE=76) and children 1-2 (MOE=92).

‚ Acute toxicity (LED10 = 0.25 mg/kg): Margins of exposure (MOEs) based on thehighest residue determination for each commodity (Tier 2) were below the health protectivestandard of 100 for all subpopulations at the 95th and 99th user day percentiles. The lowestMOEs at any percentile were found among infants, reaching 6 at the 99th percentile and 16 atthe 95th percentile for non-nursing infants <1 yr. For all infants these values were 6 and 19,respectively, while for nursing infants <1 yr they were 9 and 17. Because these values were solow, Tier 3 / Monte Carlo analysis was triggered.

Monte Carlo-derived MOEs at the 99.9th percentile fell below the health-protective standard of100 for almost all subpopulations. As with the point estimate data, the lowest MOEs occurredamong infants and young children 1-2 years, reaching 19 for non-nursing infants <1 yr at the99.9th percentile. Even at the 99th percentile there were many subpopulations registering MOEsbelow 100, including one (non-hispanic non-white non-black) that included adults. Allsubpopulations showed MOEs greater than 100 at the 95th percentile in the Monte Carloanalysis.

‚ Chronic toxicity: As with acute exposure, the highest predicted chronic exposure wasto children 1-2 yr, generating a MOE of 763. A chronic dietary health concern was,consequently, not indicated for carbaryl.

‚ Oncogenic risk: Oncogenic risk ranged between 2.54x10-6 and 3.83x10-6 for the adultpopulations analyzed. As this range was greater than the health-protective target value of 10-6,dietary consumption of carbaryl was considered to constitute an oncogenic risk.

Reference doses (RfDs). Oral doses of carbaryl below a calculated RfD were consideredunlikely to pose a risk to human health. RfDs were calculated for acute and chronic dietaryexposure scenarios by dividing the critical oral NOEL or LED10 values by an uncertainty factor of100 to account for variations in sensitivity in animal and human populations.

‚ RfDacute = 0.01 mg/kg if the acute NOEL of 1 mg/kg is used in the RfD calculation.Acute dietary exposures calculated using the point estimate approach at the 95th percentileexceeded the RfDacute for all infants, nursing infants <1 yr, non-nursing infants <1 yr, children 1-2yr and children 3-5 yr. Using the Monte Carlo approach at the 99.9th percentile, the RfDacute wasexceeded for all infants, non-nursing infants <1 yr and children 1-2 yr. These data suggest thatmitigation of carbaryl in food sources may be warranted.

‚ RfDacute = 0.0025 mg/kg if the acute LED10 of 0.25 mg/kg is used in the RfDcalculation. Acute dietary exposures calculated using both the point estimate approach at the95th percentile and the Monte Carlo approach at the 99.9th percentile exceeded the RfDacute forall of the subpopulations that yielded sufficient user day data. These data also suggest thatmitigation of carbaryl in food sources may be warranted.

‚ RfDchronic = 0.005 mg/kg/day. This value exceeded all chronic dietary exposureestimates.

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Tolerance assessment. A separate acute tolerance assessment was conducted for each“high-contributor” commodity, defined for the tolerance assessment as those commoditiesproviding greater than 5% of the total carbaryl consumption in the Tier 2 point estimatecalculations at the 95th percentile as indicated by the Critical Exposure Contribution analysis forinfants and children 1-2 yr. These commodities included blueberries, peaches, asparagus,apricots, blackberries and apples. MOEs of less than 100 were indicated for every commodityexamined where there were sufficient user days available, regardless of which critical acutetoxicity value was used in the DEEM calculation. Consequently, many tolerance values maywarrant reevaluation.

A chronic exposure assessment using residue levels set to the established carbaryl toleranceswas not attempted, as it was highly improbable that single or multiple commodities containingpesticide levels at tolerance would be consumed habitually.

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Appendix I. Benchmark dose extrapolation for induction of slight hypotonic gait inpregnant Sprague-Dawley rats (Robinson and Broxup, 1997)

Robinson and Broxup (1997) rat acute neurotoxicity study with carbarylSlight hypotonic gait data in males (top dose deleted)Probit model; slope parameter not restrictedRisk type: "Extra risk"

10% benchmark response: ==================================================================== Probit Model $Revision: 2.1 $ $Date: 2000/02/26 03:38:53 $ Input Data File:C:\BMDS\DATA\CARBARYL_HYPOTONIC_GAIT_NORMALIZED_MEAN_GD_6_TO_20.(d) Gnuplot Plotting File: C:\BMDS\DATA\CARBARYL_HYPOTONIC_GAIT_NORMALIZED_MEAN_GD_6_TO_20.plt Wed May 06 09:39:08 2009 ====================================================================

BMDS MODEL RUN ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ The form of the probability function is:

P[response] = CumNorm(Intercept+Slope*Dose),

0.1

0.2

0.3

0.4

0.5

0.6

0 0.2 0.4 0.6 0.8 1

Frac

tion

Affe

cted

dose

Probit Model with 0.95 Confidence Level

09:39 05/06 2009

BMDL BMD

ProbitBMD Lower Bound

196

where CumNorm(.) is the cumulative normal distribution function

Dependent variable = COLUMN3 Independent variable = COLUMN1 Slope parameter is not restricted

Total number of observations = 3 Total number of records with missing values = 0 Maximum number of iterations = 250 Relative Function Convergence has been set to: 1e-008 Parameter Convergence has been set to: 1e-008

Default Initial (and Specified) Parameter Values background = 0 Specified intercept = -0.648276 slope = 0.454457

Asymptotic Correlation Matrix of Parameter Estimates

( *** The model parameter(s) -background have been estimated at a boundary point, or have been specified by the user, and do not appear in the correlation matrix )

intercept slope

intercept 1 -0.65

slope -0.65 1

Parameter Estimates

Variable Estimate Std. Err. intercept -0.658436 0.198162 slope 0.461902 0.326088

Analysis of Deviance Table

Model Log(likelihood) Deviance Test DF P-value Full model -47.3395 Fitted model -47.3503 0.0215168 1 0.8834

197

Reduced model -48.3536 2.02813 2 0.3627

AIC: 98.7005

Goodness of Fit

Scaled Dose Est._Prob. Expected Observed Size Residual ------------------------------------------------------------------------ 0.0000 0.2551 6.582 7 26 0.0983 0.1000 0.2702 6.944 7 26 -0.1083 1.0000 0.4221 10.974 11 26 0.01013

Chi-square = 0.02 DF = 1 P-value = 0.8834

Benchmark Dose Computation

Specified effect = 0.1

Risk Type = Extra risk

Confidence level = 0.95

BMD = 0.470798

BMDL = 0.249141

198

Appendix II. Benchmark dose extrapolation for brain cholinesterase inhibition in femaledogs after 52 weeks of exposure to dietary carbaryl (Hamada, 1987)

Hamada (1987) dog 1-yr dietary study with carbarylBrain cholinesterase data in femalesHill model, n>1Risk type: "Relative risk"

10% benchmark response:==================================================================== Hill Model. $Revision: 2.1 $ $Date: 2000/10/11 21:21:23 $ Input Data File: D:\BMDS\UNSAVED1.(d) Gnuplot Plotting File: D:\BMDS\UNSAVED1.plt Mon Dec 05 15:53:22 2005 ====================================================================

BMDS MODEL RUN ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ The form of the response function is:

Y[dose] = intercept + v*dose^n/(k^n + dose^n)

Dependent variable = MEAN

199

Independent variable = dose rho is set to 0 Power parameter restricted to be greater than 1 A constant variance model is fit

Total number of dose groups = 4 Total number of records with missing values = 0 Maximum number of iterations = 250 Relative Function Convergence has been set to: 1e-008 Parameter Convergence has been set to: 1e-008

Default Initial Parameter Values alpha = 0.670558 rho = 0 Specified intercept = 9 v = -3.2 n = 1.2784 k = 3.28889

Asymptotic Correlation Matrix of Parameter Estimates

( *** The model parameter(s) -n have been estimated at a boundary point, or have been specified by the user, and do not appear in the correlation matrix )

alpha rho intercept v k

alpha 1 0 0 0 0

rho 0 1 0 0 0

intercept 0 0 1 0 0

v 0 0 0 1 0

k 0 0 0 0 1

Parameter Estimates

Variable Estimate Std. Err. alpha 0.812608 1 rho 0 1 intercept 8.95158 1

200

v -3.35799 1 n 1 NA k 4.65005 1

NA - Indicates that this parameter has hit a bound implied by some inequality constraint and thus has no standard error.

Table of Data and Estimated Values of Interest

Dose N Obs Mean Obs Std Dev Est Mean Est Std Dev Chi^2 Res.------ --- -------- ----------- -------- ----------- ----------

0 6 9 1.23 8.95 0.901 0.0537 3.7 6 7.2 0.64 7.46 0.901 -0.292 11 6 7 1.19 6.59 0.901 0.453 34.4 6 5.8 0.48 5.99 0.901 -0.215

Model Descriptions for likelihoods calculated

Model A1: Yij = Mu(i) + e(ij) Var{e(ij)} = Sigma^2

Model A2: Yij = Mu(i) + e(ij) Var{e(ij)} = Sigma(i)^2

Model R: Yi = Mu + e(i) Var{e(i)} = Sigma^2

Degrees of freedom for Test A1 vs fitted <= 0

Likelihoods of Interest

Model Log(likelihood) DF AIC A1 -8.444034 5 26.888069 A2 -5.016409 8 26.032817 fitted -9.509932 4 27.019865 R -21.130889 2 46.261778

Test 1: Does response and/or variances differ among dose levels (A2 vs. R) Test 2: Are Variances Homogeneous (A1 vs A2)

201

Test 3: Does the Model for the Mean Fit (A1 vs. fitted)

Tests of Interest

Test -2*log(Likelihood Ratio) Test df p-value

Test 1 32.229 6 <.0001 Test 2 6.85525 3 0.07666 Test 3 2.1318 0 NA

The p-value for Test 1 is less than .05. There appears to be adifference between response and/or variances among the dose levels.It seems appropriate to model the data

The p-value for Test 2 is greater than .05. A homogeneous variance model appears to be appropriate here

NA - Degrees of freedom for Test 3 are less than or equal to 0. The Chi-Square test for fit is not valid Benchmark Dose ComputationSpecified effect = 0.1

Risk Type = Relative risk

Confidence level = 0.95

BMD = 1.69014

BMDL = 0.46739

202

Appendix III. Benchmark dose extrapolation for hemangiosarcoma / hemangioma data inmale mice (Hamada, 1993b)

Quantal linear model; top dose deleted (10% benchmark dose lines included in graph)

To calculate the oncogenic potency at a risk of 10-6:

risk ÷ dose (i.e., LED10 x 10-5) = potency10-6 ÷ (69.045 x 10-5) = 1.45 x 10-3 (mg/kg/day)-1

Hamada (1993b) mouse 2-yr dietary oncogenicity study with carbarylHemangiosarcoma / hemangioma data in malesQuantal linear modelRisk type: "Extra risk"==================================================================== Quantal Linear Model $Revision: 2.2 $ $Date: 2000/03/17 22:27:16 $ Input Data File: C:\BMDS\DATA\CARBARYL_MOUSE_ONCO_HAMADA_1993.(d) Gnuplot Plotting File: C:\BMDS\DATA\CARBARYL_MOUSE_ONCO_HAMADA_1993.plt Tue Jan 19 11:19:27 2010 ====================================================================

BMDS MODEL RUN ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~

0

0.05

0.1

0.15

0.2

0.25

0.3

0.35

0 50 100 150 200 250

Frac

tion

Affe

cted

dose

Quantal Linear Model with 0.95 Confidence Level

11:19 01/19 2010

BMDL BMD

Quantal LinearBMD Lower Bound

203

The form of the probability function is:

P[response] = background + (1-background)*[1-EXP(-slope*dose)]

Dependent variable = COLUMN3 Independent variable = COLUMN1

Total number of observations = 3 Total number of records with missing values = 0 Maximum number of iterations = 250 Relative Function Convergence has been set to: 1e-008 Parameter Convergence has been set to: 1e-008

Default Initial (and Specified) Parameter Values Background = 0.0373134 Slope = 0.00085274 Power = 1 Specified

Asymptotic Correlation Matrix of Parameter Estimates

( *** The model parameter(s) -Power have been estimated at a boundary point, or have been specified by the user, and do not appear in the correlation matrix )

Background Slope

Background 1 -0.52

Slope -0.52 1

Parameter Estimates

Variable Estimate Std. Err. Background 0.0516686 0.0221186 Slope 0.000763212 0.000410313

Analysis of Deviance Table

Model Log(likelihood) Deviance Test DF P-value

204

Full model -57.6212 Fitted model -58.4014 1.5605 1 0.2116 Reduced model -60.6016 5.96091 2 0.05077

AIC: 120.803

Goodness of Fit

Scaled Dose Est._Prob. Expected Observed Size Residual ------------------------------------------------------------------------ 0.0000 0.0517 3.410 2 66 -0.7841 14.7300 0.0623 4.110 6 66 0.9628 145.9900 0.1517 10.464 10 69 -0.1559

Chi-square = 1.57 DF = 1 P-value = 0.2108

Benchmark Dose Computation

Specified effect = 0.1

Risk Type = Extra risk

Confidence level = 0.95

BMD = 138.049

BMDL = 69.045

205

Appendix IV. Benchmark dose extrapolation for brain cholinesterase inhibition data infemale rats following acute inhalation exposure (Weinberg, 2008)

Weinberg (2008) rat acute inhalation toxicity study with carbarylBrain cholinesterase inhibition data in malesPower modelRisk type: "Relative risk"

==================================================================== Power Model. $Revision: 2.1 $ $Date: 2000/10/11 20:57:36 $ Input Data File: C:\BMDS\UNSAVED1.(d) Gnuplot Plotting File: C:\BMDS\UNSAVED1.plt Fri Mar 20 16:06:46 2009 ====================================================================

BMDS MODEL RUN ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ The form of the response function is:

Y[dose] = control + slope * dose^power

Dependent variable = MEAN Independent variable = COLUMN1

38000

40000

42000

44000

46000

48000

50000

52000

54000

0 10 20 30 40 50 60 70

Mea

n R

espo

nse

dose

Power Model with 0.95 Confidence Level

16:06 03/20 2009

BMDBMDL

Power

206

rho is set to 0 The power is not restricted A constant variance model is fit

Total number of dose groups = 4 Total number of records with missing values = 0 Maximum number of iterations = 250 Relative Function Convergence has been set to: 1e-008 Parameter Convergence has been set to: 1e-008

Default Initial Parameter Values alpha = 4.73226e+006 rho = 0 Specified control = 51181 slope = -813.168 power = 0.616791

Asymptotic Correlation Matrix of Parameter Estimates

alpha rho control slope power

alpha 1 -1 -0.096 0.15 0.14

rho -1 1 0.096 -0.15 -0.14

control -0.096 0.096 1 -0.63 -0.49

slope 0.15 -0.15 -0.63 1 0.97

power 0.14 -0.14 -0.49 0.97 1

Parameter Estimates

Variable Estimate Std. Err. alpha 4.40772e+006 2.01428e+008 rho 0 4.25088 control 51313.4 925.597 slope -1432.98 732.141 power 0.493027 0.11873

Table of Data and Estimated Values of Interest

207

Dose N Obs Mean Obs Std Dev Est Mean Est Std Dev Chi^2 Res.------ --- -------- ----------- -------- ----------- ----------

0 5 5.12e+004 2.41e+003 5.13e+004 2.1e+003 -0.0631 10 5 4.78e+004 2.97e+003 4.69e+004 2.1e+003 0.439 27 5 4.28e+004 1.4e+003 4.4e+004 2.1e+003 -0.573 65 5 4.05e+004 1.53e+003 4.01e+004 2.1e+003 0.197

Model Descriptions for likelihoods calculated

Model A1: Yij = Mu(i) + e(ij) Var{e(ij)} = Sigma^2

Model A2: Yij = Mu(i) + e(ij) Var{e(ij)} = Sigma(i)^2

Model R: Yi = Mu + e(i) Var{e(i)} = Sigma^2

Likelihoods of Interest

Model Log(likelihood) DF AIC A1 -161.467702 5 332.935403 A2 -159.577513 8 335.155026 fitted -162.988677 4 333.977355 R -179.187770 2 362.375539

Test 1: Does response and/or variances differ among dose levels (A2 vs. R) Test 2: Are Variances Homogeneous (A1 vs A2) Test 3: Does the Model for the Mean Fit (A1 vs. fitted)

Tests of Interest

Test -2*log(Likelihood Ratio) df p-value

Test 1 39.2205 6 <.00001 Test 2 3.78038 3 0.2862 Test 3 3.04195 1 0.08114

The p-value for Test 1 is less than .05. There appears to be adifference between response and/or variances among the dose levels.It seems appropriate to model the data

208

The p-value for Test 2 is greater than .05. A homogeneous variance model appears to be appropriate here

The p-value for Test 3 is greater than .05. The model chosen appears to adequately describe the data

Benchmark Dose ComputationSpecified effect = 0.1

Risk Type = Relative risk

Confidence level = 0.95

BMD = 13.294

BMDL = 5.51202

209

Appendix IV (continued). Summary of benchmark dose analysis for brain cholinesteraseinhibition following acute inhalation exposure (2nd cohort) (Weinberg, 2008)

Relative risk, values expressed as mg/m3

ED05 LED05 ED10 LED10

Male brain

Linear n/a n/a n/a n/a

Polynomial n/a n/a n/a n/a

Power (power >1) 12.95 10.82 15.90 21.65

Power (unrestricted power) 8.31 3.04 20.40 11.56

Hill (n>1) 14.51 10.46 19.47 12.91

Hill (n unrestricted) 14.51 10.46 19.47 12.91

Female brain

Linear n/a n/a n/a n/a

Polynomial n/a n/a n/a n/a

Power (power >1) 15.93 12.00 31.87 26.00

Power (unrestricted power) 3.26 0.65 13.29 5.51

Hill (n>1) 8.13 3.72 14.15 9.29

Hill (n unrestricted) 8.13 3.15 14.15 9.45

210

Appendix V. DEEM-FCID® Acute Dietary Exposure Assessment and Risk Calculations -Point Estimate (Tier 2) and Monte Carlo (Tier 3)

V-1. Acute Residue Levels - Point Estimate and Monte Carlos ApproachesFilename: H:\ARubin\Corel\CARBARYL\NEW DIETARY August 2009\DEEM files\cbl point estimate1.R98Chemical: carbarylRfD(Chronic): 0 mg/kg bw/day NOEL(Chronic): 0 mg/kg bw/dayRfD(Acute): 0 mg/kg bw/day NOEL(Acute): 0 mg/kg bw/dayDate created/last modified: 12-10-2009/10:36:46/14 Program ver. 2.03--------------------------------------------------------------------------------

EPA Crop Commodity Name Def Res Adj.Factors RDL Comment Code Grp (ppm) #1 #2 Pntr-------- ---- ------------------------------- ---------- ------ ------ --- -------01010500 1AB Beet, garden, roots 0.006000 1.000 1.000 PDP, 2 Full comment: PDP, 2006-7 (carrot)01010501 1AB Beet, garden, roots-babyfood 0.006000 1.000 1.000 PDP, 2 Full comment: PDP, 2006-7 (carrot)01010520 1A Beet, sugar 0.006000 1.000 0.040 PDP, 2 Full comment: PDP, 2006-7 (carrot)01010521 1A Beet, sugar-babyfood 0.006000 1.000 0.040 PDP, 2 Full comment: PDP, 2006-7 (carrot)01010530 1A Beet, sugar, molasses 0.006000 1.000 0.040 PDP, 2 Full comment: PDP, 2006-7 (carrot)01010531 1A Beet, sugar, molasses-babyfood 0.006000 1.000 0.040 PDP, 2 Full comment: PDP, 2006-7 (carrot)01010670 1AB Burdock 0.006000 1.000 1.000 PDP, 2 Full comment: PDP, 2006-7 (carrot)01010780 1AB Carrot 0.006000 1.000 1.000 1 PDP, 2 Full comment: PDP, 2006-701010781 1AB Carrot-babyfood 0.006000 1.000 1.000 1 PDP, 2 Full comment: PDP, 2006-701010790 1AB Carrot, juice 0.006000 1.000 1.000 PDP, 2 Full comment: PDP, 2006-701010840 1AB Celeriac 0.006000 1.000 1.000 PDP, 2 Full comment: PDP, 2006-7 (carrot)01011000 1AB Chicory, roots 0.006000 1.000 1.000 PDP, 2 Full comment: PDP, 2006-7 (carrot)01011680 1AB Ginseng, dried 0.006000 1.000 1.000 PDP, 2 Full comment: PDP, 2006-7 (carrot)01011900 1AB Horseradish 0.006000 1.000 1.000 PDP, 2 Full comment: PDP, 2006-7 (carrot)01012500 1AB Parsley, turnip rooted 0.006000 1.000 1.000 PDP, 2 Full comment: PDP, 2006-7 (carrot)01012510 1AB Parsnip 0.006000 1.000 1.000 PDP, 2 Full comment: PDP, 2006-7 (carrot)01012511 1AB Parsnip-babyfood 0.006000 1.000 1.000 PDP, 2 Full comment: PDP, 2006-7 (carrot)01013140 1AB Radish, roots 0.006000 1.000 1.000 PDP, 2 Full comment: PDP, 2006-7 (carrot)01013160 1AB Radish, Oriental, roots 0.006000 1.000 1.000 PDP, 2 Full comment: PDP, 2006-7 (carrot)01013270 1AB Rutabaga 0.006000 1.000 1.000 PDP, 2 Full comment: PDP, 2006-7 (carrot)01013310 1AB Salsify, roots 0.006000 1.000 1.000 PDP, 2 Full comment: PDP, 2006-7 (carrot)01013880 1AB Turnip, roots 0.006000 1.000 1.000 PDP, 2 Full comment: PDP, 2006-7 (carrot)01030150 1CD Arrowroot, flour 0.013000 1.000 1.000 PDP, 2 Full comment: PDP, 2003-4 (sweet potato)01030151 1CD Arrowroot, flour-babyfood 0.013000 1.000 1.000 PDP, 2 Full comment: PDP, 2003-4 (sweet potato)01030170 1CD Artichoke, Jerusalem 0.013000 1.000 1.000 PDP, 2 Full comment: PDP, 2003-4 (sweet potato)

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01030820 1CD Cassava 0.013000 1.000 1.000 PDP, 2 Full comment: PDP, 2003-4 (sweet potato)01030821 1CD Cassava-babyfood 0.013000 1.000 1.000 PDP, 2 Full comment: PDP, 2003-4 (sweet potato)01031390 1CD Dasheen, corm 0.013000 1.000 1.000 PDP, 2 Full comment: PDP, 2003-4 (sweet potato)01031660 1CD Ginger 0.013000 1.000 1.000 PDP, 2 Full comment: PDP, 2003-4 (sweet potato)01031661 1CD Ginger-babyfood 0.013000 1.000 1.000 PDP, 2 Full comment: PDP, 2003-4 (sweet potato)01031670 1CD Ginger, dried 0.013000 1.000 1.000 PDP, 2 Full comment: PDP, 2003-4 (sweet potato)01032960 1C Potato, chips 0.008000 1.000 0.040 2 PDP, 2 Full comment: PDP, 2000-201032970 1C Potato, dry (granules/ flakes) 0.008000 1.000 0.400 2 PDP, 2 Full comment: PDP, 2000-201032971 1C Potato, dry (granules/ flakes)-b 0.008000 1.000 0.400 2 PDP, 2 Full comment: PDP, 2000-201032980 1C Potato, flour 0.008000 1.000 6.500 2 PDP, 2 Full comment: PDP, 2000-201032981 1C Potato, flour-babyfood 0.008000 1.000 6.500 2 PDP, 2 Full comment: PDP, 2000-201032990 1C Potato, tuber, w/peel 210-Cooked; Fresh or N/S; Cook Meth N/S 0.008000 1.000 1.000 2 PDP, 2 Full comment: PDP, 2000-2 211-Cooked; Fresh or N/S; Baked 0.008000 1.000 1.200 2 PDP, 2 Full comment: PDP, 2000-2 212-Cooked; Fresh or N/S; Boiled 0.008000 1.000 2.500 2 PDP, 2 Full comment: PDP, 2000-2 213-Cooked; Fresh or N/S; Fried 0.008000 1.000 0.040 2 PDP, 2 Full comment: PDP, 2000-201032991 1C Potato, tuber, w/peel-babyfood 0.008000 1.000 1.000 2 PDP, 2 Full comment: PDP, 2000-201033000 1C Potato, tuber, w/o peel 110-Uncooked; Fresh or N/S; Cook Meth N/S 0.008000 1.000 1.000 2 PDP, 2 Full comment: PDP, 2000-2 210-Cooked; Fresh or N/S; Cook Meth N/S 0.008000 1.000 1.000 2 PDP, 2 Full comment: PDP, 2000-2 211-Cooked; Fresh or N/S; Baked 0.008000 1.000 1.200 2 PDP, 2 Full comment: PDP, 2000-2 212-Cooked; Fresh or N/S; Boiled 0.008000 1.000 2.500 2 PDP, 2 Full comment: PDP, 2000-2 213-Cooked; Fresh or N/S; Fried 0.008000 1.000 0.040 2 PDP, 2 Full comment: PDP, 2000-2 221-Cooked; Frozen; Baked 0.008000 1.000 1.000 2 PDP, 2 Full comment: PDP, 2000-2 223-Cooked; Frozen; Fried 0.008000 1.000 0.040 2 PDP, 2 Full comment: PDP, 2000-2 232-Cooked; Dried; Boiled 0.008000 1.000 2.500 2 PDP, 2 Full comment: PDP, 2000-2 233-Cooked; Dried; Fried 0.008000 1.000 0.040 2 PDP, 2 Full comment: PDP, 2000-2 240-Cooked; Canned; Cook Meth N/S 0.008000 1.000 1.000 2 PDP, 2 Full comment: PDP, 2000-2 242-Cooked; Canned; Boiled 0.008000 1.000 2.500 2 PDP, 2 Full comment: PDP, 2000-2 252-Cooked; Cured etc; Boiled 0.008000 1.000 2.500 2 PDP, 2 Full comment: PDP, 2000-2

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253-Cooked; Cured etc; Fried 0.008000 1.000 0.040 2 PDP, 2 Full comment: PDP, 2000-201033001 1C Potato, tuber, w/o peel-babyfood 0.008000 1.000 1.000 2 PDP, 2 Full comment: PDP, 2000-201033660 1CD Sweet potato 0.013000 1.000 1.000 4 PDP, 2 Full comment: PDP, 2003-401033661 1CD Sweet potato-babyfood 0.013000 1.000 1.000 4 PDP, 2 Full comment: PDP, 2003-401033710 1CD Tanier, corm 0.013000 1.000 1.000 PDP, 2 Full comment: PDP, 2003-4 (sweet potato)01033870 1CD Turmeric 0.013000 1.000 1.000 PDP, 2 Full comment: PDP, 2003-4 (sweet potato)01034060 1CD Yam, true 0.013000 1.000 1.000 PDP, 2 Full comment: PDP, 2003-4 (sweet potato)01034070 1CD Yam bean 0.013000 1.000 1.000 PDP, 2 Full comment: PDP, 2003-4 (sweet potato)02000510 2 Beet, garden, tops 0.093000 1.000 1.000 PDP, 2 Full comment: PDP, 2006 (spinach)02001010 2 Chicory, tops 0.093000 1.000 1.000 PDP, 2 Full comment: PDP, 2006 (spinach)02001400 2 Dasheen, leaves 0.093000 1.000 1.000 PDP, 2 Full comment: PDP, 2006 (spinach)02003150 2 Radish, tops 0.093000 1.000 1.000 PDP, 2 Full comment: PDP, 2006 (spinach)02003170 2 Radish, Oriental, tops 0.093000 1.000 1.000 PDP, 2 Full comment: PDP, 2006 (spinach)02003320 2 Salsify, tops 0.093000 1.000 1.000 PDP, 2 Full comment: PDP, 2006 (spinach)04011380 4A Dandelion, leaves 0.093000 1.000 1.000 PDP, 2 Full comment: PDP, 2006 (spinach)04011500 4A Endive 0.093000 1.000 1.000 PDP, 2 Full comment: PDP, 2006 (spinach)04012040 4A Lettuce, head 0.005000 1.000 1.000 5 PDP, 2 Full comment: PDP, 2004-504012050 4A Lettuce, leaf 0.005000 1.000 1.000 5 PDP, 2 Full comment: PDP, 2004-504012480 4A Parsley, leaves 0.093000 1.000 1.000 PDP, 2 Full comment: PDP, 2006 (spinach)04013550 4A Spinach 110-Uncooked; Fresh or N/S; Cook Meth N/S 0.093000 1.000 1.000 6 PDP, 2 Full comment: PDP, 2006 210-Cooked; Fresh or N/S; Cook Meth N/S 0.093000 1.000 1.000 6 PDP, 2 Full comment: PDP, 2006 211-Cooked; Fresh or N/S; Baked 0.093000 1.000 1.000 6 PDP, 2 Full comment: PDP, 2006 212-Cooked; Fresh or N/S; Boiled 0.093000 1.000 1.000 6 PDP, 2 Full comment: PDP, 2006 213-Cooked; Fresh or N/S; Fried 0.093000 1.000 1.000 6 PDP, 2 Full comment: PDP, 2006 215-Cooked; Fresh or N/S; Boiled/baked 0.093000 1.000 1.000 6 PDP, 2 Full comment: PDP, 2006 220-Cooked; Frozen; Cook Meth N/S 0.093000 1.000 1.000 6 PDP, 2 Full comment: PDP, 2006 221-Cooked; Frozen; Baked 0.093000 1.000 1.000 6 PDP, 2 Full comment: PDP, 2006 222-Cooked; Frozen; Boiled 0.093000 1.000 1.000 6 PDP, 2 Full comment: PDP, 2006 232-Cooked; Dried; Boiled 0.093000 1.000 1.000 6 PDP, 2 Full comment: PDP, 2006 240-Cooked; Canned; Cook Meth N/S 0.008000 1.000 1.000 7 PDP, 2

213

Full comment: PDP, 2004 242-Cooked; Canned; Boiled 0.008000 1.000 1.000 7 PDP, 2 Full comment: PDP, 200404013551 4A Spinach-babyfood 240-Cooked; Canned; Cook Meth N/S 0.008000 1.000 1.000 7 PDP, 2 Full comment: PDP, 200404020760 4B Cardoon 3.000000 1.000 1.000 PDP, 2 Full comment: PDP, 2007 (celery tolerance excedence)04020850 4B Celery 3.000000 1.000 1.000 8 PDP, 2 Full comment: PDP, 2007 (tolerance excedence)04020851 4B Celery-babyfood 3.000000 1.000 1.000 8 PDP, 2 Full comment: PDP, 2007 (tolerance excedence)04020860 4B Celery, juice 3.000000 1.000 1.000 PDP, 2 Full comment: PDP, 2007 (tolerance excedence)04020870 4B Celtuce 3.000000 1.000 1.000 PDP, 2 Full comment: PDP, 2007 (celery tolerance excedence)04021520 4B Fennel, Florence 3.000000 1.000 1.000 PDP, 2 Full comment: PDP, 2007 (celery tolerance excedence)04023220 4B Rhubarb 3.000000 1.000 1.000 PDP, 2 Full comment: PDP, 2007 (celery tolerance excedence)04023670 4B Swiss chard 3.000000 1.000 1.000 PDP, 2 Full comment: PDP, 2007 (celery tolerance excedence)05010610 5A Broccoli 0.003000 1.000 1.000 9 PDP, 2 Full comment: PDP, 2006-705010611 5A Broccoli-babyfood 0.003000 1.000 1.000 9 PDP, 2 Full comment: PDP, 2006-7 (broccoli)05010620 5A Broccoli, Chinese 0.003000 1.000 1.000 PDP, 2 Full comment: PDP, 2006-7 (broccoli)05010640 5A Brussels sprouts 110-Uncooked; Fresh or N/S; Cook Meth N/S 0.003000 1.000 1.000 PDP, 2 Full comment: PDP, 2006-7 (broccoli) 212-Cooked; Fresh or N/S; Boiled 0.003000 1.000 0.100 PDP, 2 Full comment: PDP, 2006-7 (broccoli) 222-Cooked; Frozen; Boiled 0.003000 1.000 0.100 PDP, 2 Full comment: PDP, 2006-7 (broccoli)05010690 5A Cabbage 110-Uncooked; Fresh or N/S; Cook Meth N/S 0.003000 1.000 1.000 PDP, 2 Full comment: PDP, 2006-7 (broccoli) 150-Uncooked; Cured etc; Cook Meth N/S 0.003000 1.000 1.000 PDP, 2 Full comment: PDP, 2006-7 (broccoli) 210-Cooked; Fresh or N/S; Cook Meth N/S 0.003000 1.000 0.100 PDP, 2 Full comment: PDP, 2006-7 (broccoli) 211-Cooked; Fresh or N/S; Baked 0.003000 1.000 0.100 PDP, 2 Full comment: PDP, 2006-7 (broccoli) 212-Cooked; Fresh or N/S; Boiled 0.003000 1.000 0.100 PDP, 2 Full comment: PDP, 2006-7 (broccoli) 213-Cooked; Fresh or N/S; Fried 0.003000 1.000 0.100 PDP, 2 Full comment: PDP, 2006-7 (broccoli) 221-Cooked; Frozen; Baked 0.003000 1.000 0.100 PDP, 2 Full comment: PDP, 2006-7 (broccoli) 230-Cooked; Dried; Cook Meth N/S 0.003000 1.000 0.100 PDP, 2 Full comment: PDP, 2006-7 (broccoli) 232-Cooked; Dried; Boiled 0.003000 1.000 0.100 PDP, 2 Full comment: PDP, 2006-7 (broccoli) 240-Cooked; Canned; Cook Meth N/S 0.003000 1.000 0.100 PDP, 2 Full comment: PDP, 2006-7 (broccoli) 242-Cooked; Canned; Boiled 0.003000 1.000 0.100 PDP, 2

214

Full comment: PDP, 2006-7 (broccoli) 245-Cooked; Canned; Boiled/baked 0.003000 1.000 0.100 PDP, 2 Full comment: PDP, 2006-7 (broccoli) 250-Cooked; Cured etc; Cook Meth N/S 0.003000 1.000 0.100 PDP, 2 Full comment: PDP, 2006-7 (broccoli) 255-Cooked; Cured etc; Boiled/baked 0.003000 1.000 0.100 PDP, 2 Full comment: PDP, 2006-7 (broccoli)05010710 5A Cabbage, Chinese, napa 0.003000 1.000 1.000 PDP, 2 Full comment: PDP, 2006-7 (broccoli)05010720 5A Cabbage, Chinese, mustard 0.003000 1.000 1.000 PDP, 2 Full comment: PDP, 2006-7 (broccoli)05010830 5A Cauliflower 0.003000 1.000 1.000 PDP, 2 Full comment: PDP, 2006-7 (broccoli)05011960 5A Kohlrabi 0.003000 1.000 1.000 PDP, 2 Full comment: PDP, 2006-7 (broccoli)05020630 5B Broccoli raab 1.700000 1.000 1.000 PDP, 2 Full comment: PDP, 2006-7 (collards)05020700 5B Cabbage, Chinese, bok choy 1.700000 1.000 1.000 PDP, 2 Full comment: PDP, 2006-7 (collards)05021170 5B Collards 1.700000 1.000 1.000 10 PDP, 2 Full comment: PDP, 2006-705021940 5B Kale 0.230000 1.000 1.000 11 PDP, 2 Full comment: PDP, 2006-705022290 5B Mustard greens 1.700000 1.000 1.000 PDP, 2 Full comment: PDP, 2006-7 (collards)05023180 5B Rape greens 1.700000 1.000 1.000 PDP, 2 Full comment: PDP, 2006-7 (collards)05023890 5B Turnip, greens 1.700000 1.000 1.000 80 PDP, 2 Full comment: PDP, 2006-7 (collards)06003470 6 Soybean, seed 0.003000 1.000 1.000 12 PDP, 2 Full comment: PDP, 2004-506003480 6 Soybean, flour 0.003000 1.000 1.000 PDP, 2 Full comment: PDP, 2004-5 (soybeans)06003481 6 Soybean, flour-babyfood 0.003000 1.000 1.000 PDP, 2 Full comment: PDP, 2004-5 (soybeans)06003490 6 Soybean, soy milk 0.003000 1.000 1.000 PDP, 2 Full comment: PDP, 2004-5 (soybeans)06003491 6 Soybean, soy milk-babyfood or in 0.003000 1.000 1.000 PDP, 2 Full comment: PDP, 2004-5 (soybeans)06003500 6 Soybean, oil 0.003000 1.000 0.005 PDP, 2 Full comment: PDP, 2004-5 (soybeans)06003501 6 Soybean, oil-babyfood 0.003000 1.000 0.005 PDP, 2 Full comment: PDP, 2004-5 (soybeans)06010430 6A Bean, snap, succulent 0.530000 1.000 1.000 71 PDP, 2 Full comment: PDP, 2005 & 2007 (green beans)06010431 6A Bean, snap, succulent-babyfood 0.530000 1.000 1.000 71 PDP, 2 Full comment: PDP, 2005 & 2007 (green beans)06012570 6A Pea, edible podded, succulent 110-Uncooked; Fresh or N/S; Cook Meth N/S 0.052000 1.000 1.000 74 PDP 20 Full comment: PDP 2001-3, 2006 (sweet peas) 210-Cooked; Fresh or N/S; Cook Meth N/S 0.052000 1.000 0.150 74 PDP 20 Full comment: PDP 2001-3, 2006 (sweet peas) 212-Cooked; Fresh or N/S; Boiled 0.052000 1.000 0.150 74 PDP 20 Full comment: PDP 2001-3, 2006 (sweet peas) 213-Cooked; Fresh or N/S; Fried 0.052000 1.000 0.150 74 PDP 20 Full comment: PDP 2001-3, 2006 (sweet peas) 220-Cooked; Frozen; Cook Meth N/S 0.052000 1.000 0.150 74 PDP 20 Full comment: PDP 2001-3, 2006 (sweet peas) 221-Cooked; Frozen; Baked 0.052000 1.000 0.150 74 PDP 20 Full comment: PDP 2001-3, 2006 (sweet peas)

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06030300 6C Bean, black, seed 0.003000 1.000 1.000 PDP 20 Full comment: PDP 2004-5 (soybeans)06030320 6C Bean, broad, seed 0.003000 1.000 1.000 PDP 20 Full comment: PDP 2004-5 (soybeans)06030340 6C Bean, cowpea, seed 0.003000 1.000 1.000 PDP 20 Full comment: PDP 2004-5 (soybeans)06030350 6C Bean, great northern, seed 0.003000 1.000 1.000 PDP 20 Full comment: PDP 2004-5 (soybeans)06030360 6C Bean, kidney, seed 0.003000 1.000 1.000 PDP 20 Full comment: PDP 2004-5 (soybeans)06030380 6C Bean, lima, seed 0.003000 1.000 1.000 PDP 20 Full comment: PDP 2004-5 (soybeans)06030390 6C Bean, mung, seed 0.003000 1.000 1.000 PDP 20 Full comment: PDP 2004-5 (soybeans)06030400 6C Bean, navy, seed 0.003000 1.000 1.000 PDP 20 Full comment: PDP 2004-5 (soybeans)06030410 6C Bean, pink, seed 0.003000 1.000 1.000 PDP 20 Full comment: PDP 2004-5 (soybeans)06030420 6C Bean, pinto, seed 0.003000 1.000 1.000 PDP 20 Full comment: PDP 2004-5 (soybeans)06030980 6C Chickpea, seed 0.003000 1.000 1.000 PDP 20 Full comment: PDP 2004-5 (soybeans)06030981 6C Chickpea, seed-babyfood 0.003000 1.000 1.000 PDP 20 Full comment: PDP 2004-5 (soybeans)06030990 6C Chickpea, flour 0.003000 1.000 1.000 PDP 20 Full comment: PDP 2004-5 (soybeans)06031820 6C Guar, seed 0.003000 1.000 1.000 PDP 20 Full comment: PDP 2004-5 (soybeans)06031821 6C Guar, seed-babyfood 0.003000 1.000 1.000 PDP 20 Full comment: PDP 2004-5 (soybeans)06032030 6C Lentil, seed 0.003000 1.000 1.000 PDP 20 Full comment: PDP 2004-5 (soybeans)06032560 6C Pea, dry 0.003000 1.000 1.000 PDP 20 Full comment: PDP 2004-5 (soybeans)06032561 6C Pea, dry-babyfood 0.003000 1.000 1.000 PDP 20 Full comment: PDP 2004-5 (soybeans)06032580 6C Pea, pigeon, seed 0.003000 1.000 1.000 PDP 20 Full comment: PDP 2004-5 (soybeans)08001480 8 Eggplant 0.180000 1.000 1.000 13 PDP, 2 Full comment: PDP, 2005-608002340 8 Okra 150-Uncooked; Cured etc; Cook Meth N/S 0.810000 1.000 1.000 PDP, 2 Full comment: PDP, 2002-4 (sweet bell peppers) 210-Cooked; Fresh or N/S; Cook Meth N/S 0.810000 1.000 0.610 PDP, 2 Full comment: PDP, 2002-4 (sweet bell peppers) 212-Cooked; Fresh or N/S; Boiled 0.810000 1.000 0.180 PDP, 2 Full comment: PDP, 2002-4 (sweet bell peppers) 213-Cooked; Fresh or N/S; Fried 0.810000 1.000 0.610 PDP, 2 Full comment: PDP, 2002-4 (sweet bell peppers) 220-Cooked; Frozen; Cook Meth N/S 0.810000 1.000 0.610 PDP, 2 Full comment: PDP, 2002-4 (sweet bell peppers) 222-Cooked; Frozen; Boiled 0.810000 1.000 0.180 PDP, 2 Full comment: PDP, 2002-4 (sweet bell peppers) 240-Cooked; Canned; Cook Meth N/S 0.810000 1.000 0.610 PDP, 2 Full comment: PDP, 2002-4 (sweet bell peppers) 242-Cooked; Canned; Boiled 0.810000 1.000 0.180 PDP, 2 Full comment: PDP, 2002-4 (sweet bell peppers)08002700 8 Pepper, bell 0.810000 1.000 1.000 14 PDP, 2 Full comment: PDP, 2002-408002701 8 Pepper, bell-babyfood 0.810000 1.000 1.000 14 PDP, 2 Full comment: PDP, 2002-408002710 8 Pepper, bell, dried 0.810000 1.000 1.000 14 PDP, 2

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Full comment: PDP, 2002-408002711 8 Pepper, bell, dried-babyfood 0.810000 1.000 1.000 14 PDP, 2 Full comment: PDP, 2002-408002720 8 Pepper, nonbell 0.810000 1.000 1.000 PDP, 2 Full comment: PDP, 2002-408002721 8 Pepper, nonbell-babyfood 0.810000 1.000 1.000 PDP, 2 Full comment: PDP, 2002-408002730 8 Pepper, nonbell, dried 0.810000 1.000 1.000 PDP, 2 Full comment: PDP, 2002-408003740 8 Tomatillo 0.006000 1.000 1.000 PDP, 2 Full comment: PDP, 2007 (tomato)08003750 8 Tomato 0.006000 1.000 1.000 15 PDP, 2 Full comment: PDP, 200708003751 8 Tomato-babyfood 0.006000 1.000 1.000 15 PDP, 2 Full comment: PDP, 200708003760 8 Tomato, paste 0.011000 1.000 0.650 16 PDP, 2 Full comment: PDP, 2001 (canned tomato paste)08003761 8 Tomato, paste-babyfood 0.011000 1.000 0.650 16 PDP, 2 Full comment: PDP, 2001 (canned tomato paste)08003770 8 Tomato, puree 0.011000 1.000 0.650 16 PDP, 2 Full comment: PDP, 2001 (canned tomato paste)08003771 8 Tomato, puree-babyfood 0.011000 1.000 0.650 16 PDP, 2 Full comment: PDP, 2001 (canned tomato paste)08003780 8 Tomato, dried 0.006000 1.000 0.520 PDP, 2 Full comment: PDP, 2007 (tomato)08003781 8 Tomato, dried-babyfood 0.006000 1.000 0.520 PDP, 2 Full comment: PDP, 2007 (tomato)08003790 8 Tomato, juice 0.011000 1.000 0.520 PDP, 2 Full comment: PDP, 2001 (canned tomato)09010750 9A Cantaloupe 0.610000 1.000 1.000 17 PDP, 2 Full comment: PDP, 2004-509010800 9A Casaba 0.610000 1.000 1.000 PDP, 2 Full comment: PDP, 2004-5 (cantaloupe)09011870 9A Honeydew melon 0.610000 1.000 1.000 78 PDP, 2 Full comment: PDP, 2004-5 (cantaloupe)09013990 9A Watermelon 0.007000 1.000 1.000 18 PDP, 2 Full comment: PDP, 2005-609014000 9A Watermelon, juice 0.007000 1.000 1.000 PDP, 2 Full comment: PDP, 2005-609020210 9B Balsam pear 0.200000 1.000 1.000 PDP, 2 Full comment: PDP, 2002-4 (cucumber)09020880 9B Chayote, fruit 0.200000 1.000 1.000 PDP, 2 Full comment: PDP, 2002-4 (cucumber)09021020 9B Chinese waxgourd 0.008000 1.000 1.000 PDP, 2 Full comment: PDP, 2004-6 (winter squash)09021350 9B Cucumber 0.200000 1.000 1.000 19 PDP, 2 Full comment: PDP, 2002-409023080 9B Pumpkin 0.008000 1.000 1.000 PDP, 2 Full comment: PDP, 2004-6 (winter squash)09023090 9B Pumpkin, seed 0.008000 1.000 1.000 PDP, 2 Full comment: PDP, 2004-6 (winter squash)09023560 9B Squash, summer 0.003000 1.000 1.000 29 PDP, 2 Full comment: PDP, 2006-709023561 9B Squash, summer-babyfood 0.003000 1.000 1.000 29 PDP, 2 Full comment: PDP, 2006-709023570 9B Squash, winter 0.008000 1.000 1.000 30 PDP, 2 Full comment: PDP, 2004-609023571 9B Squash, winter-babyfood 0.008000 1.000 1.000 30 PDP, 2 Full comment: PDP, 2004-610001060 10 Citrus citron 0.120000 1.000 1.000 PDP, 2 Full comment: PDP, 2004-5 (orange)10001070 10 Citrus hybrids 0.120000 1.000 1.000 PDP, 2 Full comment: PDP, 2004-5 (orange)10001080 10 Citrus, oil 0.120000 1.000 1.000 PDP, 2 Full comment: PDP, 2004-5 (orange)10001800 10 Grapefruit 0.039000 1.000 1.000 31 PDP, 2 Full comment: PDP, 2005-610001810 10 Grapefruit, juice 0.039000 1.000 2.100 PDP, 2

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Full comment: PDP, 2005-6 (grapefruit)10001970 10 Kumquat 0.120000 1.000 1.000 PDP, 2 Full comment: PDP, 2004-5 (orange)10001990 10 Lemon 0.120000 1.000 1.000 PDP, 2 Full comment: PDP, 2004-5 (orange)10002000 10 Lemon, juice 0.120000 1.000 2.000 PDP, 2 Full comment: PDP, 2004-5 (orange)10002001 10 Lemon, juice-babyfood 0.120000 1.000 2.000 PDP, 2 Full comment: PDP, 2004-5 (orange)10002010 10 Lemon, peel 0.120000 1.000 1.160 PDP, 2 Full comment: PDP, 2004-5 (orange)10002060 10 Lime 0.120000 1.000 1.000 PDP, 2 Full comment: PDP, 2004-5 (orange)10002070 10 Lime, juice 0.120000 1.000 2.000 PDP, 2 Full comment: PDP, 2004-5 (orange)10002071 10 Lime, juice-babyfood 0.120000 1.000 2.000 PDP, 2 Full comment: PDP, 2004-5 (orange)10002400 10 Orange 0.120000 1.000 1.000 32 PDP, 2 Full comment: PDP, 2004-510002410 10 Orange, juice 0.017000 1.000 1.000 33 PDP, 2 Full comment: PDP, 2004-610002411 10 Orange, juice-babyfood 0.017000 1.000 1.000 33 PDP, 2 Full comment: PDP, 2004-610002420 10 Orange, peel 0.120000 1.000 1.270 PDP, 2 Full comment: PDP, 2004-5 (orange)10003070 10 Pummelo 0.120000 1.000 1.000 PDP, 2 Full comment: PDP, 2004-5 (orange)10003690 10 Tangerine 0.120000 1.000 1.000 PDP, 2 Full comment: PDP, 2004-5 (orange)10003700 10 Tangerine, juice 0.120000 1.000 2.300 PDP, 2 Full comment: PDP, 2004-5 (orange)11000070 11 Apple, fruit with peel 0.490000 1.000 1.000 34 PDP, 2 Full comment: PDP, 2004-511000080 11 Apple, peeled fruit 0.490000 1.000 1.000 34 PDP, 2 Full comment: PDP, 2004-511000081 11 Apple, peeled fruit-babyfood 0.490000 1.000 1.000 34 PDP, 2 Full comment: PDP, 2004-511000090 11 Apple, dried 0.490000 1.000 2.580 PDP, 2 Full comment: PDP, 2004-5 (apple)11000091 11 Apple, dried-babyfood 0.490000 1.000 2.580 PDP, 2 Full comment: PDP, 2004-5 (apple)11000100 11 Apple, juice 0.031000 1.000 1.000 35 PDP, 2 Full comment: PDP, 200711000101 11 Apple, juice-babyfood 0.031000 1.000 1.000 35 PDP, 2 Full comment: PDP, 200711000110 11 Apple, sauce 0.230000 1.000 1.000 36 PDP, 2 Full comment: PDP, 200611000111 11 Apple, sauce-babyfood 0.230000 1.000 1.000 36 PDP, 2 Full comment: PDP, 200611001290 11 Crabapple 0.490000 1.000 1.000 PDP, 2 Full comment: PDP, 2004-5 (apple)11002100 11 Loquat 0.490000 1.000 1.000 PDP, 2 Full comment: PDP, 2004-5 (apple)11002660 11 Pear 0.460000 1.000 1.000 37 PDP, 2 Full comment: PDP, 2004-511002661 11 Pear-babyfood 0.460000 1.000 1.000 37 PDP, 2 Full comment: PDP, 2004-511002670 11 Pear, dried 0.460000 1.000 2.580 PDP, 2 Full comment: PDP, 2004-511002680 11 Pear, juice 0.460000 1.000 0.370 37 PDP, 2 Full comment: PDP, 2004-5 (pear)11002681 11 Pear, juice-babyfood 0.460000 1.000 0.370 37 PDP, 2 Full comment: PDP, 2004-5 (pear)11003100 11 Quince 0.490000 1.000 1.000 PDP, 2 Full comment: PDP, 2004-5 (apple)12000120 12 Apricot 1.500000 1.000 1.000 77 PDP, 2 Full comment: PDP, 2007 (nectarine)12000121 12 Apricot-babyfood 1.500000 1.000 1.000 77 PDP, 2

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Full comment: PDP, 2007 (nectarine)12000130 12 Apricot, dried 1.500000 1.000 6.000 77 PDP, 2 Full comment: PDP, 2007 (nectarine)12000140 12 Apricot, juice 1.500000 1.000 1.000 77 PDP, 2 Full comment: PDP, 2007 (nectarine)12000141 12 Apricot, juice-babyfood 1.500000 1.000 1.000 77 PDP, 2 Full comment: PDP, 2007 (nectarine)12000900 12 Cherry 0.840000 1.000 1.000 38 PDP, 2 Full comment: PDP, 200712000901 12 Cherry-babyfood 0.840000 1.000 1.000 38 PDP, 2 Full comment: PDP, 200712000910 12 Cherry, juice 0.840000 1.000 1.500 PDP, 2 Full comment: PDP, 2007 (cherry)12000911 12 Cherry, juice-babyfood 0.840000 1.000 1.500 PDP, 2 Full comment: PDP, 2007 (cherry)12002300 12 Nectarine 1.500000 1.000 1.000 39 PDP, 2 Full comment: PDP, 200712002600 12 Peach 110-Uncooked; Fresh or N/S; Cook Meth N/S 0.670000 1.000 1.000 40 PDP, 2 Full comment: PDP, 2006-7 120-Uncooked; Frozen; Cook Meth N/S 0.670000 1.000 1.000 40 PDP, 2 Full comment: PDP, 2006-7 130-Uncooked; Dried; Cook Meth N/S 0.670000 1.000 7.000 40 PDP, 2 Full comment: PDP, 2006-7 210-Cooked; Fresh or N/S; Cook Meth N/S 0.670000 1.000 1.000 40 PDP, 2 Full comment: PDP, 2006-7 211-Cooked; Fresh or N/S; Baked 0.670000 1.000 1.000 40 PDP, 2 Full comment: PDP, 2006-7 213-Cooked; Fresh or N/S; Fried 0.670000 1.000 1.000 40 PDP, 2 Full comment: PDP, 2006-7 221-Cooked; Frozen; Baked 0.670000 1.000 1.000 40 PDP, 2 Full comment: PDP, 2006-7 223-Cooked; Frozen; Fried 0.670000 1.000 1.000 40 PDP, 2 Full comment: PDP, 2006-7 240-Cooked; Canned; Cook Meth N/S 0.670000 1.000 1.000 40 PDP, 2 Full comment: PDP, 2006-712002601 12 Peach-babyfood 0.670000 1.000 1.000 40 PDP, 2 Full comment: PDP, 2006-712002610 12 Peach, dried 0.670000 1.000 7.000 PDP, 2 Full comment: PDP, 2006-712002611 12 Peach, dried-babyfood 0.670000 1.000 7.000 PDP, 2 Full comment: PDP, 2006-712002620 12 Peach, juice 0.670000 1.000 1.000 PDP, 2 Full comment: PDP, 2006-7 (peach)12002621 12 Peach, juice-babyfood 0.670000 1.000 1.000 PDP, 2 Full comment: PDP, 2006-7 (peach)12002850 12 Plum 0.560000 1.000 1.000 41 PDP, 2 Full comment: PDP, 2005-612002851 12 Plum-babyfood 0.560000 1.000 1.000 41 PDP, 2 Full comment: PDP, 2005-612002860 12 Plum, prune, fresh 0.560000 1.000 1.000 41 PDP, 2 Full comment: PDP, 2005-6 (plum)12002861 12 Plum, prune, fresh-babyfood 0.560000 1.000 1.000 41 PDP, 2 Full comment: PDP, 2005-6 (plum)12002870 12 Plum, prune, dried 0.450000 1.000 1.000 42 PDP, 2 Full comment: PDP, 2005-612002871 12 Plum, prune, dried-babyfood 0.450000 1.000 1.000 42 PDP, 2 Full comment: PDP, 2005-612002880 12 Plum, prune, juice 0.560000 1.000 1.400 PDP, 2 Full comment: PDP, 2005-6 (plum)12002881 12 Plum, prune, juice-babyfood 0.560000 1.000 1.400 PDP, 2

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Full comment: PDP, 2005-6 (plum)13010550 13A Blackberry 3.790000 1.000 1.000 79 FDA, d Full comment: FDA, data from USEPA (raspberry)13010560 13A Blackberry, juice 3.790000 1.000 1.000 79 FDA, d Full comment: FDA, data from USEPA (raspberry)13010561 13A Blackberry, juice-babyfood 3.790000 1.000 1.000 79 FDA, d Full comment: FDA, data from USEPA (raspberry)13010580 13A Boysenberry 3.790000 1.000 1.000 FDA, d Full comment: FDA, data from USEPA (raspberry)13011420 13A Dewberry 3.790000 1.000 1.000 FDA, d Full comment: FDA, data from USEPA (raspberry)13012080 13A Loganberry 3.790000 1.000 1.000 FDA, d Full comment: FDA, data from USEPA (raspberry)13013200 13A Raspberry 3.790000 1.000 1.000 43 FDA, d Full comment: FDA, data from USEPA13013201 13A Raspberry-babyfood 3.790000 1.000 1.000 43 FDA, d Full comment: FDA, data from USEPA13013210 13A Raspberry, juice 3.790000 1.000 1.000 43 FDA, d Full comment: FDA, data from USEPA13013211 13A Raspberry, juice-babyfood 3.790000 1.000 1.000 43 FDA, d Full comment: FDA, data from USEPA13020570 13B Blueberry 9.700000 1.000 1.000 44 FDA, d Full comment: FDA, data from USEPA13020571 13B Blueberry-babyfood 9.700000 1.000 1.000 44 FDA, d Full comment: FDA, data from USEPA13021360 13B Currant 9.700000 1.000 1.000 FDA, d Full comment: FDA, data from USEPA13021370 13B Currant, dried 9.700000 1.000 1.000 FDA, d Full comment: FDA, data from USEPA13021490 13B Elderberry 9.700000 1.000 1.000 FDA, d Full comment: FDA, data from USEPA13021740 13B Gooseberry 9.700000 1.000 1.000 FDA, d Full comment: FDA, data from USEPA13021910 13B Huckleberry 9.700000 1.000 1.000 FDA, d Full comment: FDA, data from USEPA14000030 14 Almond 0.015000 1.000 1.000 45 PDP, 2 Full comment: PDP, 200714000031 14 Almond-babyfood 0.015000 1.000 1.000 45 PDP, 2 Full comment: PDP, 200714000040 14 Almond, oil 0.015000 1.000 1.000 PDP, 2 Full comment: PDP, 200714000041 14 Almond, oil-babyfood 0.015000 1.000 1.000 PDP, 2 Full comment: PDP, 200714000590 14 Brazil nut 0.015000 1.000 1.000 PDP, 2 Full comment: PDP, 2007 (almond)14000680 14 Butternut 0.015000 1.000 1.000 PDP, 2 Full comment: PDP, 2007 (almond)14000810 14 Cashew 0.015000 1.000 1.000 PDP, 2 Full comment: PDP, 2007 (almond)14000920 14 Chestnut 0.015000 1.000 1.000 PDP, 2 Full comment: PDP, 2007 (almond)14001550 14 Filbert 0.015000 1.000 1.000 PDP, 2 Full comment: PDP, 2007 (almond)14001560 14 Filbert, oil 0.015000 1.000 1.000 PDP, 2 Full comment: PDP, 2007 (almond)14001850 14 Hickory nut 0.015000 1.000 1.000 PDP, 2 Full comment: PDP, 2007 (almond)14002130 14 Macadamia nut 0.015000 1.000 1.000 PDP, 2 Full comment: PDP, 2007 (almond)14002690 14 Pecan 0.015000 1.000 1.000 PDP, 2 Full comment: PDP, 2007 (almond)14002820 14 Pistachio 0.015000 1.000 1.000 PDP, 2 Full comment: PDP, 2007 (almond)14003910 14 Walnut 0.015000 1.000 1.000 PDP, 2 Full comment: PDP, 2007 (almond)15001200 15 Corn, field, flour 0.008000 1.000 1.000 PDP, 2 Full comment: PDP, 2001-3 (frozen / canned corn)15001201 15 Corn, field, flour-babyfood 0.008000 1.000 1.000 PDP, 2

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Full comment: PDP, 2001-3 (frozen / canned corn)15001210 15 Corn, field, meal 0.008000 1.000 1.000 PDP, 2 Full comment: PDP, 2001-3 (frozen / canned corn)15001211 15 Corn, field, meal-babyfood 0.008000 1.000 1.000 PDP, 2 Full comment: PDP, 2001-3 (frozen / canned corn)15001220 15 Corn, field, bran 0.008000 1.000 1.000 PDP, 2 Full comment: PDP, 2001-3 (frozen / canned corn)15001230 15 Corn, field, starch 0.008000 1.000 1.000 PDP, 2 Full comment: PDP, 2001-3 (frozen / canned corn)15001231 15 Corn, field, starch-babyfood 0.008000 1.000 1.000 PDP, 2 Full comment: PDP, 2001-3 (frozen / canned corn)15001240 15 Corn, field, syrup 0.006000 1.000 1.500 49 PDP, 1 Full comment: PDP, 1998-915001241 15 Corn, field, syrup-babyfood 0.006000 1.000 1.500 49 PDP, 1 Full comment: PDP, 1998-915001250 15 Corn, field, oil 0.008000 1.000 0.250 PDP, 2 Full comment: PDP, 2001-3 (frozen / canned corn)15001251 15 Corn, field, oil-babyfood 0.008000 1.000 1.000 PDP, 2 Full comment: PDP, 2001-3 (frozen / canned corn)15001260 15 Corn, pop 0.008000 1.000 1.000 PDP, 2 Full comment: PDP, 2001-3 (frozen / canned corn)15001270 15 Corn, sweet 0.008000 1.000 1.000 48 PDP, 2 Full comment: PDP, 2001-3 (frozen / canned corn)15001271 15 Corn, sweet-babyfood 0.008000 1.000 1.000 48 PDP, 2 Full comment: PDP, 2001-3 (frozen / canned corn)15002260 15 Millet, grain 0.006000 1.000 1.000 PDP, 2 Full comment: PDP, 2005-6 (wheat)15003230 15 Rice, white 0.040000 1.000 0.030 50 PDP, 2 Full comment: PDP, 2000-215003231 15 Rice, white-babyfood 0.040000 1.000 0.030 50 PDP, 2 Full comment: PDP, 2000-215003240 15 Rice, brown 0.040000 1.000 1.000 50 PDP, 2 Full comment: PDP, 2000-215003241 15 Rice, brown-babyfood 0.040000 1.000 1.000 50 PDP, 2 Full comment: PDP, 2000-215003250 15 Rice, flour 0.040000 1.000 1.000 PDP, 2 Full comment: PDP, 2000-215003251 15 Rice, flour-babyfood 0.040000 1.000 1.000 PDP, 2 Full comment: PDP, 2000-215003260 15 Rice, bran 0.040000 1.000 0.400 PDP, 2 Full comment: PDP, 2000-215003261 15 Rice, bran-babyfood 0.040000 1.000 0.400 PDP, 2 Full comment: PDP, 2000-215003440 15 Sorghum, grain 0.008000 1.000 1.000 PDP, 2 Full comment: PDP, 2001-3 (frozen / canned corn)15003450 15 Sorghum, syrup 0.008000 1.000 1.000 PDP, 2 Full comment: PDP, 2001-3 (frozen / canned corn)15004010 15 Wheat, grain 0.006000 1.000 1.000 51 PDP, 2 Full comment: PDP, 2005-615004011 15 Wheat, grain-babyfood 0.006000 1.000 1.000 51 PDP, 2 Full comment: PDP, 2005-615004020 15 Wheat, flour 0.006000 1.000 1.000 52 PDP, 2 Full comment: PDP, 2003-415004021 15 Wheat, flour-babyfood 0.006000 1.000 1.000 52 PDP, 2 Full comment: PDP, 2003-415004030 15 Wheat, germ 0.006000 1.000 0.650 PDP, 2 Full comment: PDP, 2005-6 (wheat)15004040 15 Wheat, bran 0.006000 1.000 1.030 PDP, 2 Full comment: PDP, 2005-6 (wheat)19011440 19A Dillweed 0.093000 1.000 1.000 PDP, 2 Full comment: PDP, 2006 (spinach)19012490 19A Parsley, dried leaves 0.093000 1.000 1.000 PDP, 2 Full comment: PDP, 2006 (spinach)19012491 19A Parsley, dried leaves-babyfood 0.093000 1.000 1.000 PDP, 2 Full comment: PDP, 2006 (spinach)20001630 20 Flaxseed, oil 0.020000 1.000 1.000 Field Full comment: Field trial, 1995 (sunflower oil)20003640 20 Sunflower, seed 0.012900 1.000 1.000 Field

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Full comment: Field trial, 199520003650 20 Sunflower, oil 0.020000 1.000 1.000 Field Full comment: Field trial, 199520003651 20 Sunflower, oil-babyfood 0.020000 1.000 1.000 Field Full comment: Field trial, 199521000440 M Beef, meat 0.003600 1.000 1.000 PDP, 2 Full comment: PDP, 2001-221000441 M Beef, meat-babyfood 0.003600 1.000 1.000 PDP, 2 Full comment: PDP, 2001-221000450 M Beef, meat, dried 0.003600 1.000 1.920 PDP, 2 Full comment: PDP, 2001-221000460 M Beef, meat byproducts 0.003600 1.000 1.000 PDP, 2 Full comment: PDP, 2001-2 (beef liver)21000461 M Beef, meat byproducts-babyfood 0.003600 1.000 1.000 PDP, 2 Full comment: PDP, 2001-2 (beef liver)21000470 M Beef, fat 0.014000 1.000 1.000 PDP, 2 Full comment: PDP, 2001-221000471 M Beef,fat-babyfood 0.014000 1.000 1.000 PDP, 2 Full comment: PDP, 2001-221000480 M Beef, kidney 0.003600 1.000 1.000 PDP, 2 Full comment: PDP, 2001-2 (beef liver)21000490 M Beef, liver 0.003600 1.000 1.000 PDP, 2 Full comment: PDP, 2001-221000491 M Beef, liver-babyfood 0.003600 1.000 1.000 PDP, 2 Full comment: PDP, 2001-223001690 M Goat, meat 0.003600 1.000 1.000 PDP, 2 Full comment: PDP, 2001-2 (beef muscle)23001700 M Goat, meat byproducts 0.003600 1.000 1.000 PDP, 2 Full comment: PDP, 2001-2 (beef liver)23001710 M Goat, fat 0.014000 1.000 1.000 PDP, 2 Full comment: PDP, 2001-2 (beef fat)23001720 M Goat, kidney 0.003600 1.000 1.000 PDP, 2 Full comment: PDP, 2001-2 (beef liver)23001730 M Goat, liver 0.003600 1.000 1.000 PDP, 2 Full comment: PDP, 2001-2 (beef liver)24001890 M Horse, meat 0.003600 1.000 1.000 PDP, 2 Full comment: PDP, 2001-2 (beef muscle)25002900 M Pork, meat 0.006600 1.000 1.000 PDP, 2 Full comment: PDP, 200525002901 M Pork, meat-babyfood 0.006600 1.000 1.000 PDP, 2 Full comment: PDP, 200525002920 M Pork, meat byproducts 0.006600 1.000 1.000 PDP, 2 Full comment: PDP, 2005 (pork muscle)25002921 M Pork, meat byproducts-babyfood 0.006600 1.000 1.000 PDP, 2 Full comment: PDP, 2005 (pork muscle)25002930 M Pork, fat 0.098600 1.000 1.000 PDP, 2 Full comment: PDP, 200525002931 M Pork, fat-babyfood 0.098600 1.000 1.000 PDP, 2 Full comment: PDP, 200525002940 M Pork, kidney 0.006600 1.000 1.000 PDP, 2 Full comment: PDP, 2005 (pork muscle)25002950 M Pork, liver 0.006600 1.000 1.000 PDP, 2 Full comment: PDP, 2005 (pork muscle)26003390 M Sheep, meat 0.003600 1.000 1.000 PDP, 2 Full comment: PDP, 2001-2 (beef muscle)26003391 M Sheep, meat-babyfood 0.003600 1.000 1.000 PDP, 2 Full comment: PDP, 2001-2 (beef muscle)26003400 M Sheep, meat byproducts 0.003600 1.000 1.000 PDP, 2 Full comment: PDP, 2001-2 (beef liver)26003410 M Sheep, fat 0.014000 1.000 1.000 PDP, 2 Full comment: PDP, 2001-2 (beef fat)26003411 M Sheep, fat-babyfood 0.014000 1.000 1.000 PDP, 2 Full comment: PDP, 2001-2 (beef fat)26003420 M Sheep, kidney 0.003600 1.000 1.000 PDP, 2 Full comment: PDP, 2001-2 (beef liver)26003430 M Sheep, liver 0.003600 1.000 1.000 PDP, 2 Full comment: PDP, 2001-2 (beef liver)27002220 D Milk, fat 0.003600 1.000 1.000 75 PDP, 2

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Full comment: PDP, 2005, 2007 (heavy cream)27002221 D Milk, fat - baby food/infant for 0.003600 1.000 1.000 75 PDP, 2 Full comment: PDP, 2005, 2007 (heavy cream)27012230 D Milk, nonfat solids 0.000083 1.000 1.000 PDP, 2 Full comment: PDP, 2004-527012231 D Milk, nonfat solids-baby food/in 0.000083 1.000 1.000 PDP, 2 Full comment: PDP, 2004-5 (milk)27022240 D Milk, water 0.000083 1.000 1.000 70 PDP, 2 Full comment: PDP, 2004-5 (milk)27022241 D Milk, water-babyfood/infant form 0.000083 1.000 1.000 70 PDP, 2 Full comment: PDP, 2004-5 (milk)27032251 D Milk, sugar (lactose)-baby food/ 0.000083 1.000 1.000 PDP, 2 Full comment: PDP, 2004-5 (milk)86011000 O Water, direct, tap 0.000019 1.000 1.000 63 PDP, 2 Full comment: PDP, 2005-7 (drinking water)86012000 O Water, direct, bottled 0.000008 1.000 1.000 64 PDP, 2 Full comment: PDP, 2005-6 (bottled water)86013000 O Water, direct, other 0.000019 1.000 1.000 PDP, 2 Full comment: PDP, 2005-7 (drinking water)86014000 O Water, direct, source-NS 0.000019 1.000 1.000 PDP, 2 Full comment: PDP, 2005-7 (drinking water)86021000 O Water, indirect, tap 0.000019 1.000 1.000 63 PDP, 2 Full comment: PDP, 2005-7 (drinking water)86022000 O Water, indirect, bottled 0.000008 1.000 1.000 64 PDP, 2 Full comment: PDP, 2005-6 (bottled water)86023000 O Water, indirect, other 0.000019 1.000 1.000 PDP, 2 Full comment: PDP, 2005-7 (drinking water)86024000 O Water, indirect, source-NS 0.000019 1.000 1.000 PDP, 2 Full comment: PDP, 2005-7 (drinking water)95000190 O Asparagus 110-Uncooked; Fresh or N/S; Cook Meth N/S 15.000000 1.000 1.000 53 PDP, 2 Full comment: PDP, 2002-4 212-Cooked; Fresh or N/S; Boiled 15.000000 1.000 1.000 53 PDP, 2 Full comment: PDP, 2002-4 213-Cooked; Fresh or N/S; Fried 15.000000 1.000 1.000 53 PDP, 2 Full comment: PDP, 2002-4 222-Cooked; Frozen; Boiled 15.000000 1.000 1.000 53 PDP, 2 Full comment: PDP, 2002-4 242-Cooked; Canned; Boiled 15.000000 1.000 1.000 54 PDP, 2 Full comment: PDP, 2002-495000230 O Banana 110-Uncooked; Fresh or N/S; Cook Meth N/S 0.003000 1.000 1.000 55 PDP, 2 Full comment: PDP, 2006-7 120-Uncooked; Frozen; Cook Meth N/S 0.003000 1.000 1.000 55 PDP, 2 Full comment: PDP, 2006-7 130-Uncooked; Dried; Cook Meth N/S 0.003000 1.000 3.900 55 PDP, 2 Full comment: PDP, 2006-7 211-Cooked; Fresh or N/S; Baked 0.003000 1.000 1.000 55 PDP, 2 Full comment: PDP, 2006-7 212-Cooked; Fresh or N/S; Boiled 0.003000 1.000 1.000 55 PDP, 2 Full comment: PDP, 2006-7 213-Cooked; Fresh or N/S; Fried 0.003000 1.000 1.000 55 PDP, 2 Full comment: PDP, 2006-7 223-Cooked; Frozen; Fried 0.003000 1.000 1.000 55 PDP, 2 Full comment: PDP, 2006-7 240-Cooked; Canned; Cook Meth N/S 0.003000 1.000 1.000 55 PDP, 2 Full comment: PDP, 2006-795000730 O Cactus 0.025000 1.000 1.000 no dat

223

Full comment: no data - used highest LOD from other commodities95001300 O Cranberry 0.003000 1.000 1.000 56 PDP, 2 Full comment: PDP, 200695001301 O Cranberry-babyfood 0.003000 1.000 1.000 56 PDP, 2 Full comment: PDP, 200695001310 O Cranberry, dried 0.003000 1.000 1.000 PDP, 2 Full comment: PDP, 200695001320 O Cranberry, juice 0.003000 1.000 1.100 PDP, 2 Full comment: PDP, 200695001321 O Cranberry, juice-babyfood 0.003000 1.000 1.100 PDP, 2 Full comment: PDP, 200695001750 O Grape 0.580000 1.000 1.000 57 PDP, 2 Full comment: PDP, 2004-595001760 O Grape, juice 0.086000 1.000 1.000 58 PDP, 1 Full comment: PDP, 1998-995001761 O Grape, juice-babyfood 0.086000 1.000 1.000 58 PDP, 1 Full comment: PDP, 1998-995001780 O Grape, raisin 0.120000 1.000 1.000 59 PDP, 2 Full comment: PDP, 2006-795001790 O Grape, wine and sherry 0.086000 1.000 1.000 59 PDP, 1 Full comment: PDP, 1998-9 (grape juice)95002350 O Olive 9.830000 1.000 1.000 76 Field Full comment: Field trial, 199595002360 O Olive, oil 0.077000 1.000 1.000 Field Full comment: Field trial, 1995 (olive)95002630 O Peanut 0.010000 1.000 1.000 60 PDP, 2 Full comment: PDP, 2006 (peanut butter)95002640 O Peanut, butter 0.010000 1.000 1.000 60 PDP, 2 Full comment: PDP, 200695002650 O Peanut, oil 0.010000 1.000 0.290 PDP, 2 Full comment: PDP, 2006 (peanut butter)95002790 O Pineapple 0.110000 1.000 0.540 61 PDP, 2 Full comment: PDP, 2000-295002791 O Pineapple-babyfood 0.110000 1.000 0.540 61 PDP, 2 Full comment: PDP, 2000-295002800 O Pineapple, dried 0.110000 1.000 5.000 PDP, 2 Full comment: PDP, 2000-2 (pineapple)95002810 O Pineapple, juice 0.110000 1.000 0.540 PDP, 2 Full comment: PDP, 2000-2 (pineapple)95002811 O Pineapple, juice-babyfood 0.110000 1.000 0.540 PDP, 2 Full comment: PDP, 2000-2 (pineapple)95003590 O Strawberry 1.100000 1.000 1.000 62 PDP, 2 Full comment: PDP, 2004-595003591 O Strawberry-babyfood 1.100000 1.000 1.000 62 PDP, 2 Full comment: PDP, 2004-595003600 O Strawberry, juice 1.100000 1.000 1.000 62 PDP, 2 Full comment: PDP, 2004-5 (strawberry)95003601 O Strawberry, juice-babyfood 1.100000 1.000 1.000 62 PDP, 2 Full comment: PDP, 2004-5 (strawberry)

224

V-2. Acute Dietary Exposures and Risk Estimates - Point Estimate Approach

California Department of Pesticide Regulation Ver. 2.02DEEM-FCID ACUTE Analysis for CARBARYL (1994-98 data)Residue file: cbl point estimate 1.R98 Adjustment factor #2 used.Analysis Date: 12-10-2009/11:54:36 Residue file dated: 12-10-2009/10:36:46/14NOEL (Acute) = 0.250000 mg/kg body-wt/dayDaily totals for food and foodform consumption used.Run Comment: "Carbaryl point estimate run #11 - 12.10.09"===============================================================================

U.S. Population Daily Exposure Analysis /a--------------- (mg/kg body-weight/day) per Capita per User ----------- ----------- Mean 0.001705 0.001707 Standard Deviation 0.004102 0.004104 Standard Error of mean 0.000020 0.000020 Margin of Exposure 2/ 146 146

Percent of Person-Days that are User-Days = 99.86%

Estimated percentile of user-days falling below calculated exposure in mg/kg body-wt/day with Margin of Exposure (MOE)

Percentile Exposure MOE Percentile Exposure MOE ---------- ---------- --------- ---------- ---------- --------- 10.00 0.000050 4,958 90.00 0.003921 63 20.00 0.000103 2,419 95.00 0.006153 40 30.00 0.000210 1,191 97.50 0.009310 26 40.00 0.000396 631 99.00 0.015857 15 50.00 0.000657 380 99.50 0.022347 11 60.00 0.001024 244 99.75 0.034439 7 70.00 0.001531 163 99.90 0.052155 4 80.00 0.002284 109

Estimated percentile of per-capita days falling below calculated exposure in mg/kg body-wt/day with Margin of Exposure (MOE)

Percentile Exposure MOE Percentile Exposure MOE ---------- ---------- --------- ---------- ---------- --------- 10.00 0.000050 5,013 90.00 0.003916 63 20.00 0.000102 2,440 95.00 0.006147 40 30.00 0.000208 1,201 97.50 0.009300 26 40.00 0.000394 634 99.00 0.015846 15 50.00 0.000654 382 99.50 0.022335 11 60.00 0.001022 244 99.75 0.034415 7 70.00 0.001528 163 99.90 0.052094 4 80.00 0.002281 109-------------------------------------------------------------------------------a/ Analysis based on all two-day participant records in CSFII 1994-98 with 2 days of valid drinking water records.2/ Margin of Exposure = NOEL/ Dietary Exposure

225

Western region Daily Exposure Analysis -------------- (mg/kg body-weight/day) per Capita per User ----------- ----------- Mean 0.001949 0.001954 Standard Deviation 0.004150 0.004154 Standard Error of mean 0.000043 0.000043 Margin of Exposure 128 127

Percent of Person-Days that are User-Days = 99.76%

Estimated percentile of user-days falling below calculated exposure in mg/kg body-wt/day with Margin of Exposure (MOE)

Percentile Exposure MOE Percentile Exposure MOE ---------- ---------- --------- ---------- ---------- --------- 10.00 0.000059 4,260 90.00 0.004712 53 20.00 0.000123 2,029 95.00 0.007187 34 30.00 0.000253 987 97.50 0.010156 24 40.00 0.000485 514 99.00 0.017583 14 50.00 0.000797 313 99.50 0.025792 9 60.00 0.001229 203 99.75 0.032897 7 70.00 0.001811 138 99.90 0.049620 5 80.00 0.002692 92

Estimated percentile of per-capita days falling below calculated exposure in mg/kg body-wt/day with Margin of Exposure (MOE)

Percentile Exposure MOE Percentile Exposure MOE ---------- ---------- --------- ---------- ---------- --------- 10.00 0.000058 4,346 90.00 0.004706 53 20.00 0.000122 2,055 95.00 0.007176 34 30.00 0.000251 995 97.50 0.010147 24 40.00 0.000482 518 99.00 0.017545 14 50.00 0.000790 316 99.50 0.025787 9 60.00 0.001225 204 99.75 0.032885 7 70.00 0.001809 138 99.90 0.049597 5 80.00 0.002685 93

226

Hispanics Daily Exposure Analysis --------- (mg/kg body-weight/day) per Capita per User ----------- ----------- Mean 0.001424 0.001426 Standard Deviation 0.002782 0.002783 Standard Error of mean 0.000038 0.000038 Margin of Exposure 175 175

Percent of Person-Days that are User-Days = 99.89%

Estimated percentile of user-days falling below calculated exposure in mg/kg body-wt/day with Margin of Exposure (MOE)

Percentile Exposure MOE Percentile Exposure MOE ---------- ---------- --------- ---------- ---------- --------- 10.00 0.000052 4,769 90.00 0.003630 68 20.00 0.000104 2,407 95.00 0.005234 47 30.00 0.000187 1,339 97.50 0.007416 33 40.00 0.000329 759 99.00 0.011574 21 50.00 0.000564 443 99.50 0.015062 16 60.00 0.000888 281 99.75 0.019818 12 70.00 0.001415 176 99.90 0.034364 7 80.00 0.002104 118

Estimated percentile of per-capita days falling below calculated exposure in mg/kg body-wt/day with Margin of Exposure (MOE)

Percentile Exposure MOE Percentile Exposure MOE ---------- ---------- --------- ---------- ---------- --------- 10.00 0.000052 4,813 90.00 0.003628 68 20.00 0.000103 2,424 95.00 0.005232 47 30.00 0.000186 1,346 97.50 0.007410 33 40.00 0.000328 761 99.00 0.011566 21 50.00 0.000563 444 99.50 0.015057 16 60.00 0.000886 282 99.75 0.019815 12 70.00 0.001414 176 99.90 0.034362 7 80.00 0.002102 118

227

Non-hispanic whites Daily Exposure Analysis ------------------- (mg/kg body-weight/day) per Capita per User ----------- ----------- Mean 0.001801 0.001804 Standard Deviation 0.004329 0.004332 Standard Error of mean 0.000026 0.000026 Margin of Exposure 138 138

Percent of Person-Days that are User-Days = 99.85%

Estimated percentile of user-days falling below calculated exposure in mg/kg body-wt/day with Margin of Exposure (MOE)

Percentile Exposure MOE Percentile Exposure MOE ---------- ---------- --------- ---------- ---------- --------- 10.00 0.000053 4,747 90.00 0.004038 61 20.00 0.000107 2,329 95.00 0.006434 38 30.00 0.000228 1,097 97.50 0.009931 25 40.00 0.000433 577 99.00 0.017359 14 50.00 0.000712 351 99.50 0.025901 9 60.00 0.001083 230 99.75 0.038590 6 70.00 0.001604 155 99.90 0.056383 4 80.00 0.002346 106

Estimated percentile of per-capita days falling below calculated exposure in mg/kg body-wt/day with Margin of Exposure (MOE)

Percentile Exposure MOE Percentile Exposure MOE ---------- ---------- --------- ---------- ---------- --------- 10.00 0.000052 4,799 90.00 0.004032 61 20.00 0.000106 2,349 95.00 0.006422 38 30.00 0.000226 1,106 97.50 0.009918 25 40.00 0.000431 580 99.00 0.017345 14 50.00 0.000709 352 99.50 0.025894 9 60.00 0.001081 231 99.75 0.038568 6 70.00 0.001601 156 99.90 0.056349 4 80.00 0.002343 106

228

Non-hispanic blacks Daily Exposure Analysis ------------------- (mg/kg body-weight/day) per Capita per User ----------- ----------- Mean 0.001306 0.001308 Standard Deviation 0.003967 0.003969 Standard Error of mean 0.000055 0.000055 Margin of Exposure 191 191

Percent of Person-Days that are User-Days = 99.87%

Estimated percentile of user-days falling below calculated exposure in mg/kg body-wt/day with Margin of Exposure (MOE)

Percentile Exposure MOE Percentile Exposure MOE ---------- ---------- --------- ---------- ---------- --------- 10.00 0.000038 6,575 90.00 0.003264 76 20.00 0.000080 3,123 95.00 0.005274 47 30.00 0.000142 1,761 97.50 0.007571 33 40.00 0.000261 957 99.00 0.010680 23 50.00 0.000437 571 99.50 0.013499 18 60.00 0.000676 370 99.75 0.018918 13 70.00 0.001118 223 99.90 0.030796 8 80.00 0.001766 141

Estimated percentile of per-capita days falling below calculated exposure in mg/kg body-wt/day with Margin of Exposure (MOE)

Percentile Exposure MOE Percentile Exposure MOE ---------- ---------- --------- ---------- ---------- --------- 10.00 0.000038 6,649 90.00 0.003260 76 20.00 0.000079 3,147 95.00 0.005271 47 30.00 0.000141 1,768 97.50 0.007569 33 40.00 0.000260 961 99.00 0.010678 23 50.00 0.000436 573 99.50 0.013493 18 60.00 0.000673 371 99.75 0.018912 13 70.00 0.001115 224 99.90 0.030794 8 80.00 0.001764 141

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Non-hisp/non-white/non-black Daily Exposure Analysis ---------------------------- (mg/kg body-weight/day) per Capita per User ----------- ----------- Mean 0.001918 0.001921 Standard Deviation 0.003027 0.003029 Standard Error of mean 0.000069 0.000069 Margin of Exposure 130 130

Percent of Person-Days that are User-Days = 99.83%

Estimated percentile of user-days falling below calculated exposure in mg/kg body-wt/day with Margin of Exposure (MOE)

Percentile Exposure MOE Percentile Exposure MOE ---------- ---------- --------- ---------- ---------- --------- 10.00 0.000062 4,018 90.00 0.004804 52 20.00 0.000130 1,917 95.00 0.007145 34 30.00 0.000286 874 97.50 0.008943 27 40.00 0.000541 462 99.00 0.013094 19 50.00 0.000910 274 99.50 0.020986 11 60.00 0.001335 187 99.75 0.027210 9 70.00 0.002008 124 99.90 0.030260 8 80.00 0.002978 83

Estimated percentile of per-capita days falling below calculated exposure in mg/kg body-wt/day with Margin of Exposure (MOE)

Percentile Exposure MOE Percentile Exposure MOE ---------- ---------- --------- ---------- ---------- --------- 10.00 0.000062 4,063 90.00 0.004798 52 20.00 0.000129 1,934 95.00 0.007139 35 30.00 0.000284 880 97.50 0.008939 27 40.00 0.000539 464 99.00 0.013093 19 50.00 0.000908 275 99.50 0.020985 11 60.00 0.001326 188 99.75 0.027206 9 70.00 0.002002 124 99.90 0.030260 8 80.00 0.002975 84

230

All infants Daily Exposure Analysis ----------- (mg/kg body-weight/day) per Capita per User ----------- ----------- Mean 0.003514 0.003864 Standard Deviation 0.007497 0.007774 Standard Error of mean 0.000138 0.000150 Margin of Exposure 71 64

Percent of Person-Days that are User-Days = 90.95%

Estimated percentile of user-days falling below calculated exposure in mg/kg body-wt/day with Margin of Exposure (MOE)

Percentile Exposure MOE Percentile Exposure MOE ---------- ---------- --------- ---------- ---------- --------- 10.00 0.000017 14,329 90.00 0.010302 24 20.00 0.000035 7,164 95.00 0.014589 17 30.00 0.000087 2,868 97.50 0.021019 11 40.00 0.000255 979 99.00 0.037382 6 50.00 0.000957 261 99.50 0.047049 5 60.00 0.002221 112 99.75 0.055886 4 70.00 0.004107 60 99.90 0.072433 3 80.00 0.006448 38

Estimated percentile of per-capita days falling below calculated exposure in mg/kg body-wt/day with Margin of Exposure (MOE)

Percentile Exposure MOE Percentile Exposure MOE ---------- ---------- --------- ---------- ---------- --------- 10.00 0.000002 136,721 90.00 0.009802 25 20.00 0.000021 11,898 95.00 0.014039 17 30.00 0.000044 5,705 97.50 0.019959 12 40.00 0.000125 1,997 99.00 0.035081 7 50.00 0.000550 454 99.50 0.045608 5 60.00 0.001756 142 99.75 0.055623 4 70.00 0.003469 72 99.90 0.072328 3 80.00 0.005865 42

231

Nursing infants (<1 yr old) Daily Exposure Analysis --------------------------- (mg/kg body-weight/day) per Capita per User ----------- ----------- Mean 0.002345 0.003499 Standard Deviation 0.005976 0.007017 Standard Error of mean 0.000207 0.000291 Margin of Exposure 106 71

Percent of Person-Days that are User-Days = 67.02%

Estimated percentile of user-days falling below calculated exposure in mg/kg body-wt/day with Margin of Exposure (MOE)

Percentile Exposure MOE Percentile Exposure MOE ---------- ---------- --------- ---------- ---------- --------- 10.00 0.000010 23,992 90.00 0.010595 23 20.00 0.000021 11,996 95.00 0.013898 17 30.00 0.000031 7,997 97.50 0.017511 14 40.00 0.000093 2,698 99.00 0.026562 9 50.00 0.000489 511 99.50 0.057398 4 60.00 0.001655 151 99.75 0.072229 3 70.00 0.003702 67 99.90 0.072524 3 80.00 0.005930 42

Estimated percentile of per-capita days falling below calculated exposure in mg/kg body-wt/day with Margin of Exposure (MOE)

Percentile Exposure MOE Percentile Exposure MOE ---------- ---------- --------- ---------- ---------- --------- 10.00 0.000000 >1,000,000 90.00 0.007605 32 20.00 0.000000 >1,000,000 95.00 0.012265 20 30.00 0.000000 >1,000,000 97.50 0.015297 16 40.00 0.000011 22,896 99.00 0.023190 10 50.00 0.000026 9,446 99.50 0.037981 6 60.00 0.000097 2,586 99.75 0.057784 4 70.00 0.000985 253 99.90 0.072427 3 80.00 0.003724 67

232

Non-nursing infants (<1 yr old) Daily Exposure Analysis ------------------------------- (mg/kg body-weight/day) per Capita per User ----------- ----------- Mean 0.003955 0.003956 Standard Deviation 0.007951 0.007952 Standard Error of mean 0.000173 0.000173 Margin of Exposure 63 63

Percent of Person-Days that are User-Days = 99.98%

Estimated percentile of user-days falling below calculated exposure in mg/kg body-wt/day with Margin of Exposure (MOE)

Percentile Exposure MOE Percentile Exposure MOE ---------- ---------- --------- ---------- ---------- --------- 10.00 0.000020 12,435 90.00 0.010214 24 20.00 0.000041 6,036 95.00 0.014953 16 30.00 0.000106 2,356 97.50 0.021314 11 40.00 0.000342 731 99.00 0.037608 6 50.00 0.001045 239 99.50 0.047161 5 60.00 0.002384 104 99.75 0.048245 5 70.00 0.004217 59 99.90 0.069167 3 80.00 0.006567 38

Estimated percentile of per-capita days falling below calculated exposure in mg/kg body-wt/day with Margin of Exposure (MOE)

Percentile Exposure MOE Percentile Exposure MOE ---------- ---------- --------- ---------- ---------- --------- 10.00 0.000020 12,461 90.00 0.010213 24 20.00 0.000041 6,052 95.00 0.014953 16 30.00 0.000106 2,359 97.50 0.021312 11 40.00 0.000340 734 99.00 0.037607 6 50.00 0.001043 239 99.50 0.047161 5 60.00 0.002383 104 99.75 0.048244 5 70.00 0.004217 59 99.90 0.069166 3 80.00 0.006567 38

233

Females 13+ (preg/not nursing) Daily Exposure Analysis ------------------------------ (mg/kg body-weight/day) per Capita per User ----------- ----------- Mean 0.001299 0.001299 Standard Deviation 0.001808 0.001808 Standard Error of mean 0.000153 0.000153 Margin of Exposure 192 192

Percent of Person-Days that are User-Days = 100.00%

Estimated percentile of user-days falling below calculated exposure in mg/kg body-wt/day with Margin of Exposure (MOE)

Percentile Exposure MOE Percentile Exposure MOE ---------- ---------- --------- ---------- ---------- --------- 10.00 0.000054 4,657 90.00 0.003049 81 20.00 0.000149 1,677 95.00 0.004960 50 30.00 0.000299 836 97.50 0.006674 37 40.00 0.000496 503 99.00 0.010054 24 50.00 0.000606 412 99.50 0.011048 22 60.00 0.000929 269 99.75 0.011061 22 70.00 0.001416 176 99.90 0.011069 22 80.00 0.002000 124

Estimated percentile of per-capita days falling below calculated exposure in mg/kg body-wt/day with Margin of Exposure (MOE)

Percentile Exposure MOE Percentile Exposure MOE ---------- ---------- --------- ---------- ---------- --------- 10.00 0.000054 4,657 90.00 0.003049 81 20.00 0.000149 1,677 95.00 0.004960 50 30.00 0.000299 836 97.50 0.006674 37 40.00 0.000496 503 99.00 0.010054 24 50.00 0.000606 412 99.50 0.011048 22 60.00 0.000929 269 99.75 0.011061 22 70.00 0.001416 176 99.90 0.011069 22 80.00 0.002000 124

234

Females 13+ (nursing) Daily Exposure Analysis --------------------- (mg/kg body-weight/day) per Capita per User ----------- ----------- Mean 0.001350 0.001350 Standard Deviation 0.001568 0.001568 Standard Error of mean 0.000175 0.000175 Margin of Exposure 185 185

Percent of Person-Days that are User-Days = 100.00%

Estimated percentile of user-days falling below calculated exposure in mg/kg body-wt/day with Margin of Exposure (MOE)

Percentile Exposure MOE Percentile Exposure MOE ---------- ---------- --------- ---------- ---------- --------- 10.00 0.000114 2,188 90.00 0.003120 80 20.00 0.000193 1,298 95.00 0.004357 57 30.00 0.000370 676 97.50 0.005868 42 40.00 0.000561 445 99.00 0.008433 29 50.00 0.000930 268 99.50 0.008452 29 60.00 0.001149 217 99.75 0.008461 29 70.00 0.001541 162 99.90 0.008466 29 80.00 0.002246 111

Estimated percentile of per-capita days falling below calculated exposure in mg/kg body-wt/day with Margin of Exposure (MOE)

Percentile Exposure MOE Percentile Exposure MOE ---------- ---------- --------- ---------- ---------- --------- 10.00 0.000114 2,188 90.00 0.003120 80 20.00 0.000193 1,298 95.00 0.004357 57 30.00 0.000370 676 97.50 0.005868 42 40.00 0.000561 445 99.00 0.008433 29 50.00 0.000930 268 99.50 0.008452 29 60.00 0.001149 217 99.75 0.008461 29 70.00 0.001541 162 99.90 0.008466 29 80.00 0.002246 111

235

Children 1-2 yrs Daily Exposure Analysis ---------------- (mg/kg body-weight/day) per Capita per User ----------- ----------- Mean 0.004773 0.004773 Standard Deviation 0.009215 0.009215 Standard Error of mean 0.000144 0.000144 Margin of Exposure 52 52

Percent of Person-Days that are User-Days = 100.00%

Estimated percentile of user-days falling below calculated exposure in mg/kg body-wt/day with Margin of Exposure (MOE)

Percentile Exposure MOE Percentile Exposure MOE ---------- ---------- --------- ---------- ---------- --------- 10.00 0.000238 1,052 90.00 0.010093 24 20.00 0.000650 384 95.00 0.014194 17 30.00 0.001268 197 97.50 0.018902 13 40.00 0.002014 124 99.00 0.031084 8 50.00 0.002913 85 99.50 0.049344 5 60.00 0.003847 64 99.75 0.071039 3 70.00 0.005180 48 99.90 0.145400 1 80.00 0.006806 36

Estimated percentile of per-capita days falling below calculated exposure in mg/kg body-wt/day with Margin of Exposure (MOE)

Percentile Exposure MOE Percentile Exposure MOE ---------- ---------- --------- ---------- ---------- --------- 10.00 0.000238 1,052 90.00 0.010093 24 20.00 0.000650 384 95.00 0.014194 17 30.00 0.001268 197 97.50 0.018902 13 40.00 0.002014 124 99.00 0.031084 8 50.00 0.002913 85 99.50 0.049344 5 60.00 0.003847 64 99.75 0.071039 3 70.00 0.005180 48 99.90 0.145400 1 80.00 0.006806 36

236

Children 3-5 yrs Daily Exposure Analysis ---------------- (mg/kg body-weight/day) per Capita per User ----------- ----------- Mean 0.003835 0.003835 Standard Deviation 0.006227 0.006227 Standard Error of mean 0.000068 0.000068 Margin of Exposure 65 65

Percent of Person-Days that are User-Days = 100.00%

Estimated percentile of user-days falling below calculated exposure in mg/kg body-wt/day with Margin of Exposure (MOE)

Percentile Exposure MOE Percentile Exposure MOE ---------- ---------- --------- ---------- ---------- --------- 10.00 0.000191 1,306 90.00 0.008526 29 20.00 0.000445 562 95.00 0.011654 21 30.00 0.000883 283 97.50 0.015971 15 40.00 0.001516 164 99.00 0.024534 10 50.00 0.002227 112 99.50 0.038927 6 60.00 0.003113 80 99.75 0.050805 4 70.00 0.004289 58 99.90 0.070046 3 80.00 0.005817 42

Estimated percentile of per-capita days falling below calculated exposure in mg/kg body-wt/day with Margin of Exposure (MOE)

Percentile Exposure MOE Percentile Exposure MOE ---------- ---------- --------- ---------- ---------- --------- 10.00 0.000191 1,306 90.00 0.008526 29 20.00 0.000445 562 95.00 0.011654 21 30.00 0.000883 283 97.50 0.015971 15 40.00 0.001516 164 99.00 0.024534 10 50.00 0.002227 112 99.50 0.038927 6 60.00 0.003113 80 99.75 0.050805 4 70.00 0.004289 58 99.90 0.070046 3 80.00 0.005817 42

237

Children 6-12 yrs Daily Exposure Analysis ----------------- (mg/kg body-weight/day) per Capita per User ----------- ----------- Mean 0.002313 0.002313 Standard Deviation 0.005308 0.005308 Standard Error of mean 0.000083 0.000083 Margin of Exposure 108 108

Percent of Person-Days that are User-Days = 100.00%

Estimated percentile of user-days falling below calculated exposure in mg/kg body-wt/day with Margin of Exposure (MOE)

Percentile Exposure MOE Percentile Exposure MOE ---------- ---------- --------- ---------- ---------- --------- 10.00 0.000099 2,536 90.00 0.005230 47 20.00 0.000196 1,274 95.00 0.007621 32 30.00 0.000380 658 97.50 0.010402 24 40.00 0.000683 365 99.00 0.018623 13 50.00 0.001160 215 99.50 0.028977 8 60.00 0.001680 148 99.75 0.037449 6 70.00 0.002297 108 99.90 0.062508 3 80.00 0.003186 78

Estimated percentile of per-capita days falling below calculated exposure in mg/kg body-wt/day with Margin of Exposure (MOE)

Percentile Exposure MOE Percentile Exposure MOE ---------- ---------- --------- ---------- ---------- --------- 10.00 0.000099 2,536 90.00 0.005230 47 20.00 0.000196 1,274 95.00 0.007621 32 30.00 0.000380 658 97.50 0.010402 24 40.00 0.000683 365 99.00 0.018623 13 50.00 0.001160 215 99.50 0.028977 8 60.00 0.001680 148 99.75 0.037449 6 70.00 0.002297 108 99.90 0.062508 3 80.00 0.003186 78

238

Youth 13-19 yrs Daily Exposure Analysis --------------- (mg/kg body-weight/day) per Capita per User ----------- ----------- Mean 0.001104 0.001104 Standard Deviation 0.002229 0.002229 Standard Error of mean 0.000045 0.000045 Margin of Exposure 226 226

Percent of Person-Days that are User-Days = 100.00%

Estimated percentile of user-days falling below calculated exposure in mg/kg body-wt/day with Margin of Exposure (MOE)

Percentile Exposure MOE Percentile Exposure MOE ---------- ---------- --------- ---------- ---------- --------- 10.00 0.000042 5,890 90.00 0.002710 92 20.00 0.000077 3,257 95.00 0.004087 61 30.00 0.000125 2,007 97.50 0.005613 44 40.00 0.000216 1,156 99.00 0.011155 22 50.00 0.000371 673 99.50 0.014904 16 60.00 0.000613 407 99.75 0.019459 12 70.00 0.001019 245 99.90 0.026616 9 80.00 0.001649 151

Estimated percentile of per-capita days falling below calculated exposure in mg/kg body-wt/day with Margin of Exposure (MOE)

Percentile Exposure MOE Percentile Exposure MOE ---------- ---------- --------- ---------- ---------- --------- 10.00 0.000042 5,890 90.00 0.002710 92 20.00 0.000077 3,257 95.00 0.004087 61 30.00 0.000125 2,007 97.50 0.005613 44 40.00 0.000216 1,156 99.00 0.011155 22 50.00 0.000371 673 99.50 0.014904 16 60.00 0.000613 407 99.75 0.019459 12 70.00 0.001019 245 99.90 0.026616 9 80.00 0.001649 151

239

Adults 20-49 yrs Daily Exposure Analysis ---------------- (mg/kg body-weight/day) per Capita per User ----------- ----------- Mean 0.001252 0.001252 Standard Deviation 0.002980 0.002980 Standard Error of mean 0.000031 0.000031 Margin of Exposure 199 199

Percent of Person-Days that are User-Days = 99.98%

Estimated percentile of user-days falling below calculated exposure in mg/kg body-wt/day with Margin of Exposure (MOE)

Percentile Exposure MOE Percentile Exposure MOE ---------- ---------- --------- ---------- ---------- --------- 10.00 0.000043 5,825 90.00 0.002860 87 20.00 0.000081 3,092 95.00 0.004308 58 30.00 0.000146 1,709 97.50 0.006316 39 40.00 0.000285 876 99.00 0.011805 21 50.00 0.000490 509 99.50 0.017205 14 60.00 0.000772 323 99.75 0.025581 9 70.00 0.001159 215 99.90 0.044563 5 80.00 0.001750 142

Estimated percentile of per-capita days falling below calculated exposure in mg/kg body-wt/day with Margin of Exposure (MOE)

Percentile Exposure MOE Percentile Exposure MOE ---------- ---------- --------- ---------- ---------- --------- 10.00 0.000043 5,833 90.00 0.002860 87 20.00 0.000081 3,095 95.00 0.004308 58 30.00 0.000146 1,711 97.50 0.006316 39 40.00 0.000285 876 99.00 0.011805 21 50.00 0.000490 509 99.50 0.017204 14 60.00 0.000772 323 99.75 0.025579 9 70.00 0.001159 215 99.90 0.044562 5 80.00 0.001750 142

240

Adults 50+ yrs Daily Exposure Analysis -------------- (mg/kg body-weight/day) per Capita per User ----------- ----------- Mean 0.001635 0.001636 Standard Deviation 0.003694 0.003694 Standard Error of mean 0.000039 0.000039 Margin of Exposure 152 152

Percent of Person-Days that are User-Days = 99.98%

Estimated percentile of user-days falling below calculated exposure in mg/kg body-wt/day with Margin of Exposure (MOE)

Percentile Exposure MOE Percentile Exposure MOE ---------- ---------- --------- ---------- ---------- --------- 10.00 0.000051 4,882 90.00 0.003492 71 20.00 0.000121 2,062 95.00 0.005240 47 30.00 0.000276 905 97.50 0.007843 31 40.00 0.000494 506 99.00 0.015709 15 50.00 0.000746 335 99.50 0.025807 9 60.00 0.001085 230 99.75 0.038289 6 70.00 0.001531 163 99.90 0.053767 4 80.00 0.002174 114

Estimated percentile of per-capita days falling below calculated exposure in mg/kg body-wt/day with Margin of Exposure (MOE)

Percentile Exposure MOE Percentile Exposure MOE ---------- ---------- --------- ---------- ---------- --------- 10.00 0.000051 4,889 90.00 0.003492 71 20.00 0.000121 2,064 95.00 0.005239 47 30.00 0.000276 905 97.50 0.007843 31 40.00 0.000494 506 99.00 0.015705 15 50.00 0.000746 335 99.50 0.025806 9 60.00 0.001085 230 99.75 0.038288 6 70.00 0.001531 163 99.90 0.051157 4 80.00 0.002174 114

241

Females 13-49 yrs Daily Exposure Analysis ----------------- (mg/kg body-weight/day) per Capita per User ----------- ----------- Mean 0.001309 0.001309 Standard Deviation 0.003045 0.003045 Standard Error of mean 0.000040 0.000040 Margin of Exposure 190 190

Percent of Person-Days that are User-Days = 100.00%

Estimated percentile of user-days falling below calculated exposure in mg/kg body-wt/day with Margin of Exposure (MOE)

Percentile Exposure MOE Percentile Exposure MOE ---------- ---------- --------- ---------- ---------- --------- 10.00 0.000039 6,371 90.00 0.002979 83 20.00 0.000079 3,171 95.00 0.004568 54 30.00 0.000145 1,724 97.50 0.006530 38 40.00 0.000300 833 99.00 0.012001 20 50.00 0.000513 487 99.50 0.017171 14 60.00 0.000808 309 99.75 0.026352 9 70.00 0.001250 200 99.90 0.049063 5 80.00 0.001848 135

Estimated percentile of per-capita days falling below calculated exposure in mg/kg body-wt/day with Margin of Exposure (MOE)

Percentile Exposure MOE Percentile Exposure MOE ---------- ---------- --------- ---------- ---------- --------- 10.00 0.000039 6,371 90.00 0.002979 83 20.00 0.000079 3,171 95.00 0.004568 54 30.00 0.000145 1,724 97.50 0.006530 38 40.00 0.000300 833 99.00 0.012001 20 50.00 0.000513 487 99.50 0.017171 14 60.00 0.000808 309 99.75 0.026352 9 70.00 0.001250 200 99.90 0.049063 5 80.00 0.001848 135

242

Custom demographics 1: Adults 16-70 yrAll SeasonsAll RegionsSex: M/F-all/All RacesAge-Low: 16 yrs High: 70 yrs--------------------------------------

Daily Exposure Analysis (mg/kg body-weight/day) per Capita per User ----------- ----------- Mean 0.001318 0.001318 Standard Deviation 0.003080 0.003081 Standard Error of mean 0.000023 0.000023 Margin of Exposure 189 189

Percent of Person-Days that are User-Days = 99.98%

Estimated percentile of user-days falling below calculated exposure in mg/kg body-wt/day with Margin of Exposure (MOE)

Percentile Exposure MOE Percentile Exposure MOE ---------- ---------- --------- ---------- ---------- --------- 10.00 0.000043 5,764 90.00 0.002991 83 20.00 0.000084 2,982 95.00 0.004546 54 30.00 0.000157 1,590 97.50 0.006666 37 40.00 0.000311 803 99.00 0.012049 20 50.00 0.000526 475 99.50 0.019095 13 60.00 0.000822 304 99.75 0.025910 9 70.00 0.001224 204 99.90 0.044827 5 80.00 0.001824 137

Estimated percentile of per-capita days falling below calculated exposure in mg/kg body-wt/day with Margin of Exposure (MOE)

Percentile Exposure MOE Percentile Exposure MOE ---------- ---------- --------- ---------- ---------- --------- 10.00 0.000043 5,770 90.00 0.002990 83 20.00 0.000084 2,985 95.00 0.004546 54 30.00 0.000157 1,592 97.50 0.006666 37 40.00 0.000311 804 99.00 0.012049 20 50.00 0.000526 475 99.50 0.019093 13 60.00 0.000821 304 99.75 0.025910 9 70.00 0.001224 204 99.90 0.044826 5 80.00 0.001824 137

243

V-3. Acute Dietary Critical Exposure Contribution Analysis - Point Estimate Approach

xxxCalifornia Department of Pesticide RegulationDEEM-FCID Acute Critical Exposure Contribution Analysis (Ver 2.02)CSFII 1994-98Residue file = H:\ARubin\Corel\CARBARYL\NEW DIETARY August 2009\DEEM files\cbl pointestimate 1.R98Acute report = H:\ARubin\Corel\CARBARYL\NEW DIETARY August 2009\DEEM files\CLpe11.AC7Date and time of analysis: 12-10-2009 11:54:23Daily totals for food and foodform consumption used.Adjustment factor #2 used.Minimum exposure contribution = 1%Exposures divided by body weight

Subpopulations: 1 U.S. Population 2 Western region 3 Hispanics 4 Non-hispanic whites 5 Non-hispanic blacks 6 Non-hisp/non-white/non-black 7 All infants 8 Nursing infants (<1 yr old) 9 Non-nursing infants (<1 yr old) 10 Females 13+ (preg/not nursing) 11 Females 13+ (nursing) 12 Children 1-2 yrs 13 Children 3-5 yrs 14 Children 6-12 yrs 15 Youth 13-19 yrs 16 Adults 20-49 yrs 17 Adults 50+ yrs 18 Females 13-49 yrs 19 Custom demographics 1: Adults 16-70 yr

================================================================================U.S. PopulationLow percentile for CEC records: 95 Exposure (mg/day) = 0.006147High percentile for CEC records: 100 Exposure (mg/day) = 0.238165Number of actual records in this interval: 4147

Critical foods/foodforms for this population (as derived from these records): N=number of appearances in all records (including duplicates) %=percent of total exposure for all records (including duplicates)

Food, FF, N , Percent, Food Name --------, ---, -----, -------, -------------11000070, 110, 1220, 8.70%, Apple, fruit with peel-Uncooked; Fresh or N/S; CookMeth N/S95000190, 212, 143, 7.49%, Asparagus-Cooked; Fresh or N/S; Boiled13020570, 110, 485, 5.58%, Blueberry-Uncooked; Fresh or N/S; Cook Meth N/S95000190, 242, 65, 5.43%, Asparagus-Cooked; Canned; Boiled95001750, 110, 607, 4.39%, Grape-Uncooked; Fresh or N/S; Cook Meth N/S13020570, 211, 451, 4.28%, Blueberry-Cooked; Fresh or N/S; Baked95002350, 240, 223, 3.46%, Olive-Cooked; Canned; Cook Meth N/S95003590, 110, 505, 3.41%, Strawberry-Uncooked; Fresh or N/S; Cook Meth N/S 9010750, 110, 375, 2.93%, Cantaloupe-Uncooked; Fresh or N/S; Cook Meth N/S13020571, 240, 84, 2.93%, Blueberry-babyfood-Cooked; Canned; Cook Meth N/S12002601, 240, 238, 2.75%, Peach-babyfood-Cooked; Canned; Cook Meth N/S 4020850, 110, 464, 2.48%, Celery-Uncooked; Fresh or N/S; Cook Meth N/S12002600, 240, 576, 2.42%, Peach-Cooked; Canned; Cook Meth N/S

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12002300, 110, 134, 2.17%, Nectarine-Uncooked; Fresh or N/S; Cook Meth N/S13013200, 240, 349, 1.47%, Raspberry-Cooked; Canned; Cook Meth N/S12002600, 110, 274, 1.40%, Peach-Uncooked; Fresh or N/S; Cook Meth N/S95003600, 240, 503, 1.39%, Strawberry, juice-Cooked; Canned; Cook Meth N/S11002661, 240, 180, 1.37%, Pear-babyfood-Cooked; Canned; Cook Meth N/S 6010430, 242, 312, 1.36%, Bean, snap, succulent-Cooked; Canned; Boiled11000110, 212, 311, 1.32%, Apple, sauce-Cooked; Fresh or N/S; Boiled 5021170, 212, 69, 1.24%, Collards-Cooked; Fresh or N/S; Boiled13020570, 120, 91, 1.18%, Blueberry-Uncooked; Frozen; Cook Meth N/S11000111, 240, 265, 1.18%, Apple, sauce-babyfood-Cooked; Canned; Cook Meth N/S11002660, 110, 174, 1.13%, Pear-Uncooked; Fresh or N/S; Cook Meth N/S 4020850, 212, 382, 1.08%, Celery-Cooked; Fresh or N/S; Boiled11000100, 110, 833, 1.01%, Apple, juice-Uncooked; Fresh or N/S; Cook Meth N/S95003590, 240, 335, 0.96%, Strawberry-Cooked; Canned; Cook Meth N/S12000121, 240, 88, 0.96%, Apricot-babyfood-Cooked; Canned; Cook Meth N/S12000130, 130, 25, 0.93%, Apricot, dried-Uncooked; Dried; Cook Meth N/S13020570, 214, 79, 0.92%, Blueberry-Cooked; Fresh or N/S; Fried/baked11002660, 240, 230, 0.83%, Pear-Cooked; Canned; Cook Meth N/S13013200, 110, 351, 0.75%, Raspberry-Uncooked; Fresh or N/S; Cook Meth N/S 6010431, 240, 151, 0.74%, Bean, snap, succulent-babyfood-Cooked; Canned; CookMeth N/S95001760, 110, 254, 0.73%, Grape, juice-Uncooked; Fresh or N/S; Cook Meth N/S12000120, 240, 325, 0.63%, Apricot-Cooked; Canned; Cook Meth N/S 4020850, 210, 213, 0.60%, Celery-Cooked; Fresh or N/S; Cook Meth N/S13010550, 240, 332, 0.59%, Blackberry-Cooked; Canned; Cook Meth N/S11000081, 240, 166, 0.58%, Apple, peeled fruit-babyfood-Cooked; Canned; CookMeth N/S 6010430, 212, 256, 0.58%, Bean, snap, succulent-Cooked; Fresh or N/S; Boiled95000190, 222, 17, 0.57%, Asparagus-Cooked; Frozen; Boiled12000141, 240, 70, 0.55%, Apricot, juice-babyfood-Cooked; Canned; Cook MethN/S95001760, 240, 525, 0.53%, Grape, juice-Cooked; Canned; Cook Meth N/S13013210, 110, 25, 0.50%, Raspberry, juice-Uncooked; Fresh or N/S; Cook MethN/S 9011870, 110, 74, 0.49%, Honeydew melon-Uncooked; Fresh or N/S; Cook MethN/S 5023890, 212, 36, 0.44%, Turnip, greens-Cooked; Fresh or N/S; Boiled12002850, 110, 86, 0.42%, Plum-Uncooked; Fresh or N/S; Cook Meth N/S10002400, 110, 282, 0.41%, Orange-Uncooked; Fresh or N/S; Cook Meth N/S 4020850, 242, 34, 0.31%, Celery-Cooked; Canned; Boiled13013200, 120, 44, 0.27%, Raspberry-Uncooked; Frozen; Cook Meth N/S11002681, 240, 69, 0.27%, Pear, juice-babyfood-Cooked; Canned; Cook Meth N/S95002350, 211, 82, 0.26%, Olive-Cooked; Fresh or N/S; Baked95003600, 210, 220, 0.26%, Strawberry, juice-Cooked; Fresh or N/S; Cook MethN/S10002410, 110, 501, 0.25%, Orange, juice-Uncooked; Fresh or N/S; Cook Meth N/S13010561, 240, 15, 0.25%, Blackberry, juice-babyfood-Cooked; Canned; CookMeth N/S12000910, 210, 217, 0.22%, Cherry, juice-Cooked; Fresh or N/S; Cook Meth N/S 6010430, 222, 75, 0.22%, Bean, snap, succulent-Cooked; Frozen; Boiled12000910, 110, 15, 0.22%, Cherry, juice-Uncooked; Fresh or N/S; Cook Meth N/S95001750, 210, 217, 0.21%, Grape-Cooked; Fresh or N/S; Cook Meth N/S 8002700, 110, 155, 0.21%, Pepper, bell-Uncooked; Fresh or N/S; Cook Meth N/S 9021350, 110, 188, 0.20%, Cucumber-Uncooked; Fresh or N/S; Cook Meth N/S11002660, 210, 217, 0.20%, Pear-Cooked; Fresh or N/S; Cook Meth N/S 8002700, 210, 97, 0.20%, Pepper, bell-Cooked; Fresh or N/S; Cook Meth N/S11000101, 240, 177, 0.20%, Apple, juice-babyfood-Cooked; Canned; Cook Meth N/S13013201, 240, 77, 0.20%, Raspberry-babyfood-Cooked; Canned; Cook Meth N/S12002851, 240, 50, 0.20%, Plum-babyfood-Cooked; Canned; Cook Meth N/S12002880, 110, 20, 0.20%, Plum, prune, juice-Uncooked; Fresh or N/S; CookMeth N/S95001750, 240, 325, 0.19%, Grape-Cooked; Canned; Cook Meth N/S95003590, 120, 29, 0.19%, Strawberry-Uncooked; Frozen; Cook Meth N/S13020570, 213, 29, 0.18%, Blueberry-Cooked; Fresh or N/S; Fried 5023890, 242, 10, 0.16%, Turnip, greens-Cooked; Canned; Boiled

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95003600, 110, 19, 0.16%, Strawberry, juice-Uncooked; Fresh or N/S; Cook MethN/S12000120, 110, 20, 0.16%, Apricot-Uncooked; Fresh or N/S; Cook Meth N/S12002861, 240, 23, 0.16%, Plum, prune, fresh-babyfood-Cooked; Canned; CookMeth N/S12000900, 110, 125, 0.15%, Cherry-Uncooked; Fresh or N/S; Cook Meth N/S11000100, 240, 253, 0.15%, Apple, juice-Cooked; Canned; Cook Meth N/S 4020851, 240, 34, 0.14%, Celery-babyfood-Cooked; Canned; Cook Meth N/S 5022290, 212, 17, 0.13%, Mustard greens-Cooked; Fresh or N/S; Boiled 5021170, 242, 8, 0.13%, Collards-Cooked; Canned; Boiled 4023220, 240, 6, 0.12%, Rhubarb-Cooked; Canned; Cook Meth N/S13020570, 240, 96, 0.12%, Blueberry-Cooked; Canned; Cook Meth N/S 4020850, 215, 47, 0.12%, Celery-Cooked; Fresh or N/S; Boiled/baked13021910, 110, 1, 0.11%, Huckleberry-Uncooked; Fresh or N/S; Cook Meth N/S13013200, 211, 96, 0.11%, Raspberry-Cooked; Fresh or N/S; Baked12002620, 110, 8, 0.11%, Peach, juice-Uncooked; Fresh or N/S; Cook Meth N/S 9021350, 240, 138, 0.11%, Cucumber-Cooked; Canned; Cook Meth N/S95001761, 240, 67, 0.10%, Grape, juice-babyfood-Cooked; Canned; Cook Meth N/S10002410, 120, 217, 0.10%, Orange, juice-Uncooked; Frozen; Cook Meth N/S 4020850, 232, 19, 0.10%, Celery-Cooked; Dried; Boiled12002610, 130, 10, 0.10%, Peach, dried-Uncooked; Dried; Cook Meth N/S13010550, 110, 14, 0.09%, Blackberry-Uncooked; Fresh or N/S; Cook Meth N/S10002000, 110, 102, 0.08%, Lemon, juice-Uncooked; Fresh or N/S; Cook Meth N/S95001780, 130, 127, 0.08%, Grape, raisin-Uncooked; Dried; Cook Meth N/S13010550, 211, 5, 0.08%, Blackberry-Cooked; Fresh or N/S; Baked95003590, 211, 96, 0.08%, Strawberry-Cooked; Fresh or N/S; Baked13020570, 210, 22, 0.07%, Blueberry-Cooked; Fresh or N/S; Cook Meth N/S12000901, 240, 25, 0.07%, Cherry-babyfood-Cooked; Canned; Cook Meth N/S12000130, 211, 27, 0.07%, Apricot, dried-Cooked; Fresh or N/S; Baked12000900, 240, 119, 0.07%, Cherry-Cooked; Canned; Cook Meth N/S12000140, 240, 27, 0.07%, Apricot, juice-Cooked; Canned; Cook Meth N/S 5022290, 242, 4, 0.07%, Mustard greens-Cooked; Canned; Boiled95002810, 110, 50, 0.06%, Pineapple, juice-Uncooked; Fresh or N/S; Cook MethN/S95002810, 240, 167, 0.06%, Pineapple, juice-Cooked; Canned; Cook Meth N/S12002620, 240, 6, 0.06%, Peach, juice-Cooked; Canned; Cook Meth N/S11002680, 240, 60, 0.06%, Pear, juice-Cooked; Canned; Cook Meth N/S13010550, 120, 16, 0.06%, Blackberry-Uncooked; Frozen; Cook Meth N/S13013210, 120, 15, 0.06%, Raspberry, juice-Uncooked; Frozen; Cook Meth N/S 1033000, 212, 182, 0.06%, Potato, tuber, w/o peel-Cooked; Fresh or N/S;Boiled 8002700, 211, 84, 0.05%, Pepper, bell-Cooked; Fresh or N/S; Baked 5023890, 222, 2, 0.05%, Turnip, greens-Cooked; Frozen; Boiled13013211, 240, 15, 0.05%, Raspberry, juice-babyfood-Cooked; Canned; Cook MethN/S 4023670, 212, 4, 0.05%, Swiss chard-Cooked; Fresh or N/S; Boiled11000080, 211, 24, 0.05%, Apple, peeled fruit-Cooked; Fresh or N/S; Baked 4020850, 211, 17, 0.04%, Celery-Cooked; Fresh or N/S; Baked12000911, 240, 21, 0.04%, Cherry, juice-babyfood-Cooked; Canned; Cook MethN/S 4023220, 211, 5, 0.04%, Rhubarb-Cooked; Fresh or N/S; Baked12000900, 211, 22, 0.04%, Cherry-Cooked; Fresh or N/S; Baked95001760, 120, 16, 0.04%, Grape, juice-Uncooked; Frozen; Cook Meth N/S95000190, 110, 2, 0.04%, Asparagus-Uncooked; Fresh or N/S; Cook Meth N/S 4020850, 240, 9, 0.04%, Celery-Cooked; Canned; Cook Meth N/S11000070, 211, 9, 0.04%, Apple, fruit with peel-Cooked; Fresh or N/S; Baked95001790, 110, 52, 0.04%, Grape, wine and sherry-Uncooked; Fresh or N/S; CookMeth N/S 8002340, 210, 8, 0.04%, Okra-Cooked; Fresh or N/S; Cook Meth N/S10001810, 110, 28, 0.04%, Grapefruit, juice-Uncooked; Fresh or N/S; Cook MethN/S95002790, 240, 53, 0.04%, Pineapple-Cooked; Canned; Cook Meth N/S10002000, 210, 108, 0.04%, Lemon, juice-Cooked; Fresh or N/S; Cook Meth N/S11000100, 120, 27, 0.04%, Apple, juice-Uncooked; Frozen; Cook Meth N/S11000110, 210, 10, 0.03%, Apple, sauce-Cooked; Fresh or N/S; Cook Meth N/S

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10003690, 110, 20, 0.03%, Tangerine-Uncooked; Fresh or N/S; Cook Meth N/S12002881, 240, 8, 0.03%, Plum, prune, juice-babyfood-Cooked; Canned; CookMeth N/S 6010430, 110, 7, 0.03%, Bean, snap, succulent-Uncooked; Fresh or N/S; CookMeth N/S13013210, 240, 27, 0.03%, Raspberry, juice-Cooked; Canned; Cook Meth N/S11000080, 240, 9, 0.03%, Apple, peeled fruit-Cooked; Canned; Cook Meth N/S11000090, 130, 10, 0.03%, Apple, dried-Uncooked; Dried; Cook Meth N/S12002600, 120, 13, 0.03%, Peach-Uncooked; Frozen; Cook Meth N/S 8002700, 215, 40, 0.03%, Pepper, bell-Cooked; Fresh or N/S; Boiled/baked 8002700, 213, 31, 0.03%, Pepper, bell-Cooked; Fresh or N/S; Fried13010560, 120, 1, 0.03%, Blackberry, juice-Uncooked; Frozen; Cook Meth N/S 5020700, 210, 18, 0.03%, Cabbage, Chinese, bok choy-Cooked; Fresh or N/S;Cook Meth N/S95002350, 212, 4, 0.03%, Olive-Cooked; Fresh or N/S; Boiled10003700, 240, 41, 0.03%, Tangerine, juice-Cooked; Canned; Cook Meth N/S 9010750, 240, 3, 0.03%, Cantaloupe-Cooked; Canned; Cook Meth N/S 8002700, 212, 22, 0.03%, Pepper, bell-Cooked; Fresh or N/S; Boiled12000900, 120, 12, 0.02%, Cherry-Uncooked; Frozen; Cook Meth N/S 5021940, 212, 20, 0.02%, Kale-Cooked; Fresh or N/S; Boiled95003601, 240, 15, 0.02%, Strawberry, juice-babyfood-Cooked; Canned; CookMeth N/S12002621, 240, 7, 0.02%, Peach, juice-babyfood-Cooked; Canned; Cook Meth N/S 4013550, 212, 26, 0.02%, Spinach-Cooked; Fresh or N/S; Boiled 4020860, 110, 3, 0.02%, Celery, juice-Uncooked; Fresh or N/S; Cook Meth N/S12000120, 232, 1, 0.02%, Apricot-Cooked; Dried; Boiled12002600, 211, 15, 0.02%, Peach-Cooked; Fresh or N/S; Baked 9010800, 110, 1, 0.02%, Casaba-Uncooked; Fresh or N/S; Cook Meth N/S95002350, 210, 5, 0.02%, Olive-Cooked; Fresh or N/S; Cook Meth N/S10002000, 130, 37, 0.02%, Lemon, juice-Uncooked; Dried; Cook Meth N/S95002350, 215, 1, 0.02%, Olive-Cooked; Fresh or N/S; Boiled/baked 6010430, 210, 8, 0.02%, Bean, snap, succulent-Cooked; Fresh or N/S; CookMeth N/S13020570, 230, 4, 0.02%, Blueberry-Cooked; Dried; Cook Meth N/S 5021170, 222, 1, 0.02%, Collards-Cooked; Frozen; Boiled 8002700, 240, 12, 0.02%, Pepper, bell-Cooked; Canned; Cook Meth N/S11000090, 211, 36, 0.02%, Apple, dried-Cooked; Fresh or N/S; Baked15003251, 230, 50, 0.02%, Rice, flour-babyfood-Cooked; Dried; Cook Meth N/S 9013990, 110, 49, 0.02%, Watermelon-Uncooked; Fresh or N/S; Cook Meth N/S 4013550, 222, 10, 0.01%, Spinach-Cooked; Frozen; Boiled 5022290, 222, 1, 0.01%, Mustard greens-Cooked; Frozen; Boiled10002000, 240, 32, 0.01%, Lemon, juice-Cooked; Canned; Cook Meth N/S 8002720, 212, 10, 0.01%, Pepper, nonbell-Cooked; Fresh or N/S; Boiled12002870, 130, 14, 0.01%, Plum, prune, dried-Uncooked; Dried; Cook Meth N/S11002670, 130, 8, 0.01%, Pear, dried-Uncooked; Dried; Cook Meth N/S13010580, 120, 16, 0.01%, Boysenberry-Uncooked; Frozen; Cook Meth N/S12002600, 210, 11, 0.01%, Peach-Cooked; Fresh or N/S; Cook Meth N/S 8002340, 220, 1, 0.01%, Okra-Cooked; Frozen; Cook Meth N/S95002811, 240, 27, 0.01%, Pineapple, juice-babyfood-Cooked; Canned; Cook MethN/S13010580, 240, 25, 0.01%, Boysenberry-Cooked; Canned; Cook Meth N/S95002790, 110, 20, 0.01%, Pineapple-Uncooked; Fresh or N/S; Cook Meth N/S10002070, 240, 24, 0.01%, Lime, juice-Cooked; Canned; Cook Meth N/S11002680, 110, 8, 0.01%, Pear, juice-Uncooked; Fresh or N/S; Cook Meth N/S 8002720, 110, 7, 0.01%, Pepper, nonbell-Uncooked; Fresh or N/S; Cook MethN/S12000120, 211, 2, 0.01%, Apricot-Cooked; Fresh or N/S; Baked95001760, 210, 38, 0.01%, Grape, juice-Cooked; Fresh or N/S; Cook Meth N/S 5021940, 242, 3, 0.01%, Kale-Cooked; Canned; Boiled12000140, 110, 5, 0.01%, Apricot, juice-Uncooked; Fresh or N/S; Cook MethN/S 6010430, 213, 9, 0.01%, Bean, snap, succulent-Cooked; Fresh or N/S; Fried10002070, 110, 10, 0.01%, Lime, juice-Uncooked; Fresh or N/S; Cook Meth N/S 1032990, 212, 25, 0.01%, Potato, tuber, w/peel-Cooked; Fresh or N/S; Boiled10001800, 110, 24, 0.01%, Grapefruit-Uncooked; Fresh or N/S; Cook Meth N/S

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10001810, 240, 17, 0.01%, Grapefruit, juice-Cooked; Canned; Cook Meth N/S10002410, 240, 28, 0.01%, Orange, juice-Cooked; Canned; Cook Meth N/S13010580, 110, 4, 0.01%, Boysenberry-Uncooked; Fresh or N/S; Cook Meth N/S11000091, 230, 13, 0.01%, Apple, dried-babyfood-Cooked; Dried; Cook Meth N/S 4020850, 213, 8, 0.01%, Celery-Cooked; Fresh or N/S; Fried95002810, 120, 10, 0.01%, Pineapple, juice-Uncooked; Frozen; Cook Meth N/S 1033661, 240, 26, 0.01%, Sweet potato-babyfood-Cooked; Canned; Cook Meth N/S25002930, 210, 23, 0.01%, Pork, fat-Cooked; Fresh or N/S; Cook Meth N/S95003600, 120, 3, 0.01%, Strawberry, juice-Uncooked; Frozen; Cook Meth N/S 4020850, 214, 1, 0.01%, Celery-Cooked; Fresh or N/S; Fried/baked 8002720, 240, 12, 0.01%, Pepper, nonbell-Cooked; Canned; Cook Meth N/S 6010430, 215, 2, 0.01%, Bean, snap, succulent-Cooked; Fresh or N/S;Boiled/baked 8001480, 214, 8, 0.01%, Eggplant-Cooked; Fresh or N/S; Fried/baked10001810, 120, 2, 0.01%, Grapefruit, juice-Uncooked; Frozen; Cook Meth N/S 8002720, 210, 10, 0.01%, Pepper, nonbell-Cooked; Fresh or N/S; Cook Meth N/S 5020700, 150, 4, 0.01%, Cabbage, Chinese, bok choy-Uncooked; Cured etc;Cook Meth N/S 8002700, 222, 3, 0.01%, Pepper, bell-Cooked; Frozen; Boiled10002000, 120, 6, 0.00%, Lemon, juice-Uncooked; Frozen; Cook Meth N/S15003250, 230, 25, 0.00%, Rice, flour-Cooked; Dried; Cook Meth N/S 8002730, 212, 17, 0.00%, Pepper, nonbell, dried-Cooked; Fresh or N/S; Boiled 8002340, 213, 4, 0.00%, Okra-Cooked; Fresh or N/S; Fried 8002730, 210, 21, 0.00%, Pepper, nonbell, dried-Cooked; Fresh or N/S; CookMeth N/S13021360, 110, 2, 0.00%, Currant-Uncooked; Fresh or N/S; Cook Meth N/S25002930, 213, 14, 0.00%, Pork, fat-Cooked; Fresh or N/S; Fried15003240, 232, 8, 0.00%, Rice, brown-Cooked; Dried; Boiled11000090, 230, 11, 0.00%, Apple, dried-Cooked; Dried; Cook Meth N/S11000070, 213, 1, 0.00%, Apple, fruit with peel-Cooked; Fresh or N/S; Fried 8002340, 150, 2, 0.00%, Okra-Uncooked; Cured etc; Cook Meth N/S 8002720, 215, 5, 0.00%, Pepper, nonbell-Cooked; Fresh or N/S; Boiled/baked25002930, 250, 9, 0.00%, Pork, fat-Cooked; Cured etc; Cook Meth N/S15003251, 240, 13, 0.00%, Rice, flour-babyfood-Cooked; Canned; Cook Meth N/S 4013550, 211, 5, 0.00%, Spinach-Cooked; Fresh or N/S; Baked12000140, 120, 10, 0.00%, Apricot, juice-Uncooked; Frozen; Cook Meth N/S10002070, 120, 11, 0.00%, Lime, juice-Uncooked; Frozen; Cook Meth N/S 8002720, 150, 7, 0.00%, Pepper, nonbell-Uncooked; Cured etc; Cook Meth N/S15001240, 240, 13, 0.00%, Corn, field, syrup-Cooked; Canned; Cook Meth N/S 8002700, 214, 1, 0.00%, Pepper, bell-Cooked; Fresh or N/S; Fried/baked95002800, 130, 4, 0.00%, Pineapple, dried-Uncooked; Dried; Cook Meth N/S 8002700, 150, 6, 0.00%, Pepper, bell-Uncooked; Cured etc; Cook Meth N/S15001270, 242, 12, 0.00%, Corn, sweet-Cooked; Canned; Boiled 8003770, 240, 14, 0.00%, Tomato, puree-Cooked; Canned; Cook Meth N/S12002860, 232, 4, 0.00%, Plum, prune, fresh-Cooked; Dried; Boiled 1033000, 211, 11, 0.00%, Potato, tuber, w/o peel-Cooked; Fresh or N/S; Baked11000070, 150, 1, 0.00%, Apple, fruit with peel-Uncooked; Cured etc; CookMeth N/S11000110, 240, 5, 0.00%, Apple, sauce-Cooked; Canned; Cook Meth N/S13021370, 130, 1, 0.00%, Currant, dried-Uncooked; Dried; Cook Meth N/S10002411, 240, 5, 0.00%, Orange, juice-babyfood-Cooked; Canned; Cook MethN/S 8002700, 221, 3, 0.00%, Pepper, bell-Cooked; Frozen; Baked 9021350, 150, 5, 0.00%, Cucumber-Uncooked; Cured etc; Cook Meth N/S12000910, 240, 7, 0.00%, Cherry, juice-Cooked; Canned; Cook Meth N/S12002860, 110, 1, 0.00%, Plum, prune, fresh-Uncooked; Fresh or N/S; CookMeth N/S25002930, 253, 11, 0.00%, Pork, fat-Cooked; Cured etc; Fried10001990, 110, 3, 0.00%, Lemon-Uncooked; Fresh or N/S; Cook Meth N/S 8002720, 213, 2, 0.00%, Pepper, nonbell-Cooked; Fresh or N/S; Fried10002001, 240, 7, 0.00%, Lemon, juice-babyfood-Cooked; Canned; Cook Meth N/S95003600, 211, 3, 0.00%, Strawberry, juice-Cooked; Fresh or N/S; Baked 8001480, 212, 4, 0.00%, Eggplant-Cooked; Fresh or N/S; Boiled11000110, 221, 1, 0.00%, Apple, sauce-Cooked; Frozen; Baked 8002720, 230, 3, 0.00%, Pepper, nonbell-Cooked; Dried; Cook Meth N/S

248

15001241, 240, 7, 0.00%, Corn, field, syrup-babyfood-Cooked; Canned; CookMeth N/S95001780, 210, 4, 0.00%, Grape, raisin-Cooked; Fresh or N/S; Cook Meth N/S95001780, 211, 5, 0.00%, Grape, raisin-Cooked; Fresh or N/S; Baked95001780, 230, 7, 0.00%, Grape, raisin-Cooked; Dried; Cook Meth N/S 8003770, 210, 6, 0.00%, Tomato, puree-Cooked; Fresh or N/S; Cook Meth N/S10003700, 110, 2, 0.00%, Tangerine, juice-Uncooked; Fresh or N/S; Cook MethN/S95002350, 213, 1, 0.00%, Olive-Cooked; Fresh or N/S; Fried 5020700, 110, 1, 0.00%, Cabbage, Chinese, bok choy-Uncooked; Fresh or N/S;Cook Meth N/S 4013550, 110, 5, 0.00%, Spinach-Uncooked; Fresh or N/S; Cook Meth N/S 4020850, 150, 1, 0.00%, Celery-Uncooked; Cured etc; Cook Meth N/S95002791, 240, 5, 0.00%, Pineapple-babyfood-Cooked; Canned; Cook Meth N/S11000080, 213, 2, 0.00%, Apple, peeled fruit-Cooked; Fresh or N/S; Fried95000190, 213, 1, 0.00%, Asparagus-Cooked; Fresh or N/S; Fried15003240, 210, 4, 0.00%, Rice, brown-Cooked; Fresh or N/S; Cook Meth N/S10002000, 211, 3, 0.00%, Lemon, juice-Cooked; Fresh or N/S; Baked 4013551, 240, 4, 0.00%, Spinach-babyfood-Cooked; Canned; Cook Meth N/S95002360, 900, 3, 0.00%, Olive, oil-Refined; FF N/A; Cook Meth N/S10003700, 120, 3, 0.00%, Tangerine, juice-Uncooked; Frozen; Cook Meth N/S 9023571, 240, 5, 0.00%, Squash, winter-babyfood-Cooked; Canned; Cook MethN/S 6010430, 240, 2, 0.00%, Bean, snap, succulent-Cooked; Canned; Cook Meth N/S 8003750, 215, 4, 0.00%, Tomato-Cooked; Fresh or N/S; Boiled/baked 1010781, 240, 5, 0.00%, Carrot-babyfood-Cooked; Canned; Cook Meth N/S 9020210, 212, 1, 0.00%, Balsam pear-Cooked; Fresh or N/S; Boiled 8003770, 212, 4, 0.00%, Tomato, puree-Cooked; Fresh or N/S; Boiled11002680, 120, 3, 0.00%, Pear, juice-Uncooked; Frozen; Cook Meth N/S 8002711, 240, 3, 0.00%, Pepper, bell, dried-babyfood-Cooked; Canned; CookMeth N/S25002930, 230, 4, 0.00%, Pork, fat-Cooked; Dried; Cook Meth N/S15001241, 230, 4, 0.00%, Corn, field, syrup-babyfood-Cooked; Dried; CookMeth N/S 6010430, 221, 2, 0.00%, Bean, snap, succulent-Cooked; Frozen; Baked 8001480, 215, 1, 0.00%, Eggplant-Cooked; Fresh or N/S; Boiled/baked12002860, 211, 1, 0.00%, Plum, prune, fresh-Cooked; Fresh or N/S; Baked95002790, 210, 3, 0.00%, Pineapple-Cooked; Fresh or N/S; Cook Meth N/S10001070, 110, 1, 0.00%, Citrus hybrids-Uncooked; Fresh or N/S; Cook MethN/S 1032990, 211, 4, 0.00%, Potato, tuber, w/peel-Cooked; Fresh or N/S; Baked 8002710, 212, 1, 0.00%, Pepper, bell, dried-Cooked; Fresh or N/S; Boiled 1033000, 210, 2, 0.00%, Potato, tuber, w/o peel-Cooked; Fresh or N/S; CookMeth N/S10002000, 212, 1, 0.00%, Lemon, juice-Cooked; Fresh or N/S; Boiled15003240, 211, 3, 0.00%, Rice, brown-Cooked; Fresh or N/S; Baked25002931, 240, 2, 0.00%, Pork, fat-babyfood-Cooked; Canned; Cook Meth N/S 1033660, 242, 1, 0.00%, Sweet potato-Cooked; Canned; Boiled15001270, 212, 3, 0.00%, Corn, sweet-Cooked; Fresh or N/S; Boiled 8003790, 240, 3, 0.00%, Tomato, juice-Cooked; Canned; Cook Meth N/S95003600, 213, 2, 0.00%, Strawberry, juice-Cooked; Fresh or N/S; Fried95001780, 232, 1, 0.00%, Grape, raisin-Cooked; Dried; Boiled11000110, 211, 2, 0.00%, Apple, sauce-Cooked; Fresh or N/S; Baked25002930, 240, 2, 0.00%, Pork, fat-Cooked; Canned; Cook Meth N/S11000080, 221, 2, 0.00%, Apple, peeled fruit-Cooked; Frozen; Baked95001790, 210, 3, 0.00%, Grape, wine and sherry-Cooked; Fresh or N/S; CookMeth N/S 8002730, 240, 3, 0.00%, Pepper, nonbell, dried-Cooked; Canned; Cook MethN/S 6003490, 210, 2, 0.00%, Soybean, soy milk-Cooked; Fresh or N/S; Cook MethN/S 4013550, 215, 1, 0.00%, Spinach-Cooked; Fresh or N/S; Boiled/baked 1010780, 212, 3, 0.00%, Carrot-Cooked; Fresh or N/S; Boiled12000910, 120, 2, 0.00%, Cherry, juice-Uncooked; Frozen; Cook Meth N/S15004020, 211, 3, 0.00%, Wheat, flour-Cooked; Fresh or N/S; Baked

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8001480, 211, 1, 0.00%, Eggplant-Cooked; Fresh or N/S; Baked 1033660, 211, 2, 0.00%, Sweet potato-Cooked; Fresh or N/S; Baked 1032981, 240, 1, 0.00%, Potato, flour-babyfood-Cooked; Canned; Cook MethN/S 1033660, 212, 2, 0.00%, Sweet potato-Cooked; Fresh or N/S; Boiled25002930, 211, 2, 0.00%, Pork, fat-Cooked; Fresh or N/S; Baked15003250, 232, 2, 0.00%, Rice, flour-Cooked; Dried; Boiled11000080, 232, 1, 0.00%, Apple, peeled fruit-Cooked; Dried; Boiled 8003790, 212, 2, 0.00%, Tomato, juice-Cooked; Fresh or N/S; Boiled25002930, 242, 2, 0.00%, Pork, fat-Cooked; Canned; Boiled 1033660, 210, 2, 0.00%, Sweet potato-Cooked; Fresh or N/S; Cook Meth N/S11000080, 210, 1, 0.00%, Apple, peeled fruit-Cooked; Fresh or N/S; Cook MethN/S15001270, 222, 2, 0.00%, Corn, sweet-Cooked; Frozen; Boiled 4020850, 221, 1, 0.00%, Celery-Cooked; Frozen; Baked95000730, 110, 1, 0.00%, Cactus-Uncooked; Fresh or N/S; Cook Meth N/S15003241, 240, 2, 0.00%, Rice, brown-babyfood-Cooked; Canned; Cook Meth N/S 8003750, 240, 1, 0.00%, Tomato-Cooked; Canned; Cook Meth N/S15001240, 130, 2, 0.00%, Corn, field, syrup-Uncooked; Dried; Cook Meth N/S 8003750, 212, 2, 0.00%, Tomato-Cooked; Fresh or N/S; Boiled 8002340, 212, 1, 0.00%, Okra-Cooked; Fresh or N/S; Boiled95001750, 120, 1, 0.00%, Grape-Uncooked; Frozen; Cook Meth N/S15001241, 130, 2, 0.00%, Corn, field, syrup-babyfood-Uncooked; Dried; CookMeth N/S95001780, 110, 1, 0.00%, Grape, raisin-Uncooked; Fresh or N/S; Cook Meth N/S11000090, 210, 1, 0.00%, Apple, dried-Cooked; Fresh or N/S; Cook Meth N/S 1034070, 110, 1, 0.00%, Yam bean-Uncooked; Fresh or N/S; Cook Meth N/S 1032980, 213, 1, 0.00%, Potato, flour-Cooked; Fresh or N/S; Fried25002901, 240, 1, 0.00%, Pork, meat-babyfood-Cooked; Canned; Cook Meth N/S25002930, 212, 1, 0.00%, Pork, fat-Cooked; Fresh or N/S; Boiled95002790, 211, 1, 0.00%, Pineapple-Cooked; Fresh or N/S; Baked20003640, 211, 1, 0.00%, Sunflower, seed-Cooked; Fresh or N/S; Baked15003250, 210, 1, 0.00%, Rice, flour-Cooked; Fresh or N/S; Cook Meth N/S25002930, 221, 1, 0.00%, Pork, fat-Cooked; Frozen; Baked 6010430, 211, 1, 0.00%, Bean, snap, succulent-Cooked; Fresh or N/S; Baked21000440, 211, 1, 0.00%, Beef, meat-Cooked; Fresh or N/S; Baked 4011500, 110, 1, 0.00%, Endive-Uncooked; Fresh or N/S; Cook Meth N/S 6003490, 230, 1, 0.00%, Soybean, soy milk-Cooked; Dried; Cook Meth N/S15003241, 230, 1, 0.00%, Rice, brown-babyfood-Cooked; Dried; Cook Meth N/S 4013550, 242, 1, 0.00%, Spinach-Cooked; Canned; Boiled95001780, 213, 1, 0.00%, Grape, raisin-Cooked; Fresh or N/S; Fried 1010780, 242, 1, 0.00%, Carrot-Cooked; Canned; Boiled 1010780, 222, 1, 0.00%, Carrot-Cooked; Frozen; Boiled15004020, 231, 1, 0.00%, Wheat, flour-Cooked; Dried; Baked 9021350, 212, 1, 0.00%, Cucumber-Cooked; Fresh or N/S; Boiled15001241, 210, 1, 0.00%, Corn, field, syrup-babyfood-Cooked; Fresh or N/S;Cook Meth N/S 1010790, 110, 1, 0.00%, Carrot, juice-Uncooked; Fresh or N/S; Cook Meth N/S 8002720, 211, 1, 0.00%, Pepper, nonbell-Cooked; Fresh or N/S; Baked 1033660, 215, 1, 0.00%, Sweet potato-Cooked; Fresh or N/S; Boiled/baked21000470, 211, 1, 0.00%, Beef, fat-Cooked; Fresh or N/S; Baked15001231, 240, 1, 0.00%, Corn, field, starch-babyfood-Cooked; Canned; CookMeth N/S 8003790, 110, 1, 0.00%, Tomato, juice-Uncooked; Fresh or N/S; Cook Meth N/S95001320, 110, 1, 0.00%, Cranberry, juice-Uncooked; Fresh or N/S; Cook MethN/S95000230, 110, 1, 0.00%, Banana-Uncooked; Fresh or N/S; Cook Meth N/S

250

Western regionLow percentile for CEC records: 95 Exposure (mg/day) = 0.007176High percentile for CEC records: 100 Exposure (mg/day) = 0.238165Number of actual records in this interval: 894

Critical foods/foodforms for this population (as derived from these records): N=number of appearances in all records (including duplicates) %=percent of total exposure for all records (including duplicates)

Food, FF, N , Percent, Food Name --------, ---, -----, -------, -------------95000190, 212, 46, 9.80%, Asparagus-Cooked; Fresh or N/S; Boiled11000070, 110, 297, 8.61%, Apple, fruit with peel-Uncooked; Fresh or N/S; CookMeth N/S13020570, 110, 114, 5.55%, Blueberry-Uncooked; Fresh or N/S; Cook Meth N/S95001750, 110, 128, 4.89%, Grape-Uncooked; Fresh or N/S; Cook Meth N/S12002300, 110, 51, 4.02%, Nectarine-Uncooked; Fresh or N/S; Cook Meth N/S95002350, 240, 57, 3.68%, Olive-Cooked; Canned; Cook Meth N/S 9010750, 110, 91, 3.38%, Cantaloupe-Uncooked; Fresh or N/S; Cook Meth N/S13020571, 240, 17, 3.31%, Blueberry-babyfood-Cooked; Canned; Cook Meth N/S95003590, 110, 137, 3.28%, Strawberry-Uncooked; Fresh or N/S; Cook Meth N/S95000190, 242, 10, 2.96%, Asparagus-Cooked; Canned; Boiled 4020850, 110, 99, 2.93%, Celery-Uncooked; Fresh or N/S; Cook Meth N/S13020570, 211, 76, 2.76%, Blueberry-Cooked; Fresh or N/S; Baked13020570, 120, 20, 2.74%, Blueberry-Uncooked; Frozen; Cook Meth N/S13013200, 240, 117, 2.42%, Raspberry-Cooked; Canned; Cook Meth N/S12002600, 240, 143, 1.91%, Peach-Cooked; Canned; Cook Meth N/S95003590, 240, 114, 1.52%, Strawberry-Cooked; Canned; Cook Meth N/S13013200, 110, 92, 1.48%, Raspberry-Uncooked; Fresh or N/S; Cook Meth N/S12002600, 110, 63, 1.35%, Peach-Uncooked; Fresh or N/S; Cook Meth N/S12002601, 240, 27, 1.25%, Peach-babyfood-Cooked; Canned; Cook Meth N/S11002660, 110, 50, 1.23%, Pear-Uncooked; Fresh or N/S; Cook Meth N/S12000120, 240, 114, 1.14%, Apricot-Cooked; Canned; Cook Meth N/S11000110, 212, 64, 1.14%, Apple, sauce-Cooked; Fresh or N/S; Boiled12000130, 130, 9, 1.13%, Apricot, dried-Uncooked; Dried; Cook Meth N/S 4020850, 212, 101, 1.09%, Celery-Cooked; Fresh or N/S; Boiled13020570, 214, 23, 1.08%, Blueberry-Cooked; Fresh or N/S; Fried/baked11002660, 240, 60, 1.07%, Pear-Cooked; Canned; Cook Meth N/S13013210, 110, 10, 0.96%, Raspberry, juice-Uncooked; Fresh or N/S; Cook MethN/S13013200, 120, 14, 0.90%, Raspberry-Uncooked; Frozen; Cook Meth N/S11000100, 110, 171, 0.86%, Apple, juice-Uncooked; Fresh or N/S; Cook Meth N/S13010550, 240, 106, 0.85%, Blackberry-Cooked; Canned; Cook Meth N/S95003600, 240, 87, 0.84%, Strawberry, juice-Cooked; Canned; Cook Meth N/S95000190, 222, 4, 0.77%, Asparagus-Cooked; Frozen; Boiled11002661, 240, 24, 0.74%, Pear-babyfood-Cooked; Canned; Cook Meth N/S11000111, 240, 39, 0.71%, Apple, sauce-babyfood-Cooked; Canned; Cook Meth N/S 6010430, 242, 39, 0.63%, Bean, snap, succulent-Cooked; Canned; Boiled95001760, 110, 59, 0.58%, Grape, juice-Uncooked; Fresh or N/S; Cook Meth N/S12002850, 110, 21, 0.56%, Plum-Uncooked; Fresh or N/S; Cook Meth N/S 4020850, 242, 13, 0.55%, Celery-Cooked; Canned; Boiled 5021170, 212, 7, 0.54%, Collards-Cooked; Fresh or N/S; Boiled 9011870, 110, 17, 0.54%, Honeydew melon-Uncooked; Fresh or N/S; Cook MethN/S10002400, 110, 88, 0.54%, Orange-Uncooked; Fresh or N/S; Cook Meth N/S 4020850, 210, 46, 0.53%, Celery-Cooked; Fresh or N/S; Cook Meth N/S12000121, 240, 12, 0.48%, Apricot-babyfood-Cooked; Canned; Cook Meth N/S13021910, 110, 1, 0.46%, Huckleberry-Uncooked; Fresh or N/S; Cook Meth N/S12000120, 110, 14, 0.43%, Apricot-Uncooked; Fresh or N/S; Cook Meth N/S11000081, 240, 27, 0.42%, Apple, peeled fruit-babyfood-Cooked; Canned; CookMeth N/S12000141, 240, 10, 0.29%, Apricot, juice-babyfood-Cooked; Canned; Cook MethN/S

251

6010431, 240, 19, 0.28%, Bean, snap, succulent-babyfood-Cooked; Canned; CookMeth N/S13010561, 240, 3, 0.28%, Blackberry, juice-babyfood-Cooked; Canned; CookMeth N/S13020570, 213, 10, 0.28%, Blueberry-Cooked; Fresh or N/S; Fried12000900, 110, 33, 0.26%, Cherry-Uncooked; Fresh or N/S; Cook Meth N/S 6010430, 212, 38, 0.26%, Bean, snap, succulent-Cooked; Fresh or N/S; Boiled95003600, 110, 7, 0.25%, Strawberry, juice-Uncooked; Fresh or N/S; Cook MethN/S95003600, 210, 52, 0.23%, Strawberry, juice-Cooked; Fresh or N/S; Cook MethN/S 4020850, 215, 24, 0.23%, Celery-Cooked; Fresh or N/S; Boiled/baked10002410, 110, 90, 0.21%, Orange, juice-Uncooked; Fresh or N/S; Cook Meth N/S13013201, 240, 16, 0.21%, Raspberry-babyfood-Cooked; Canned; Cook Meth N/S95001750, 240, 93, 0.21%, Grape-Cooked; Canned; Cook Meth N/S95002350, 211, 12, 0.20%, Olive-Cooked; Fresh or N/S; Baked12000140, 240, 11, 0.20%, Apricot, juice-Cooked; Canned; Cook Meth N/S12000910, 210, 50, 0.20%, Cherry, juice-Cooked; Fresh or N/S; Cook Meth N/S95001750, 210, 50, 0.19%, Grape-Cooked; Fresh or N/S; Cook Meth N/S 4020851, 240, 7, 0.18%, Celery-babyfood-Cooked; Canned; Cook Meth N/S11002660, 210, 50, 0.18%, Pear-Cooked; Fresh or N/S; Cook Meth N/S 8002700, 210, 23, 0.18%, Pepper, bell-Cooked; Fresh or N/S; Cook Meth N/S 8002700, 110, 27, 0.17%, Pepper, bell-Uncooked; Fresh or N/S; Cook Meth N/S11002681, 240, 12, 0.16%, Pear, juice-babyfood-Cooked; Canned; Cook Meth N/S 6010430, 222, 14, 0.15%, Bean, snap, succulent-Cooked; Frozen; Boiled95003590, 211, 24, 0.15%, Strawberry-Cooked; Fresh or N/S; Baked 4023670, 212, 3, 0.15%, Swiss chard-Cooked; Fresh or N/S; Boiled 4023220, 240, 2, 0.14%, Rhubarb-Cooked; Canned; Cook Meth N/S95001760, 240, 56, 0.13%, Grape, juice-Cooked; Canned; Cook Meth N/S 9021350, 110, 31, 0.13%, Cucumber-Uncooked; Fresh or N/S; Cook Meth N/S10002410, 120, 55, 0.13%, Orange, juice-Uncooked; Frozen; Cook Meth N/S95002810, 110, 25, 0.12%, Pineapple, juice-Uncooked; Fresh or N/S; Cook MethN/S13010560, 120, 1, 0.12%, Blackberry, juice-Uncooked; Frozen; Cook Meth N/S12002620, 240, 2, 0.12%, Peach, juice-Cooked; Canned; Cook Meth N/S12002620, 110, 4, 0.11%, Peach, juice-Uncooked; Fresh or N/S; Cook Meth N/S 9021350, 240, 34, 0.11%, Cucumber-Cooked; Canned; Cook Meth N/S13010550, 120, 3, 0.10%, Blackberry-Uncooked; Frozen; Cook Meth N/S13010550, 110, 4, 0.10%, Blackberry-Uncooked; Fresh or N/S; Cook Meth N/S12002851, 240, 5, 0.10%, Plum-babyfood-Cooked; Canned; Cook Meth N/S10002000, 110, 21, 0.10%, Lemon, juice-Uncooked; Fresh or N/S; Cook Meth N/S11000101, 240, 23, 0.09%, Apple, juice-babyfood-Cooked; Canned; Cook Meth N/S11000070, 211, 3, 0.09%, Apple, fruit with peel-Cooked; Fresh or N/S; Baked12002861, 240, 4, 0.08%, Plum, prune, fresh-babyfood-Cooked; Canned; CookMeth N/S 9010800, 110, 1, 0.08%, Casaba-Uncooked; Fresh or N/S; Cook Meth N/S95001790, 110, 20, 0.07%, Grape, wine and sherry-Uncooked; Fresh or N/S; CookMeth N/S 4020850, 232, 3, 0.07%, Celery-Cooked; Dried; Boiled95002350, 215, 1, 0.07%, Olive-Cooked; Fresh or N/S; Boiled/baked 4023220, 211, 1, 0.07%, Rhubarb-Cooked; Fresh or N/S; Baked13020570, 240, 20, 0.07%, Blueberry-Cooked; Canned; Cook Meth N/S12000910, 110, 2, 0.07%, Cherry, juice-Uncooked; Fresh or N/S; Cook Meth N/S12000900, 211, 4, 0.07%, Cherry-Cooked; Fresh or N/S; Baked95000190, 110, 1, 0.06%, Asparagus-Uncooked; Fresh or N/S; Cook Meth N/S95001761, 240, 15, 0.06%, Grape, juice-babyfood-Cooked; Canned; Cook Meth N/S95001780, 130, 26, 0.06%, Grape, raisin-Uncooked; Dried; Cook Meth N/S12000130, 211, 6, 0.06%, Apricot, dried-Cooked; Fresh or N/S; Baked11002680, 240, 13, 0.06%, Pear, juice-Cooked; Canned; Cook Meth N/S 8002700, 215, 21, 0.06%, Pepper, bell-Cooked; Fresh or N/S; Boiled/baked13013200, 211, 21, 0.06%, Raspberry-Cooked; Fresh or N/S; Baked13013211, 240, 3, 0.06%, Raspberry, juice-babyfood-Cooked; Canned; Cook MethN/S95002350, 212, 2, 0.06%, Olive-Cooked; Fresh or N/S; Boiled 8002700, 213, 13, 0.05%, Pepper, bell-Cooked; Fresh or N/S; Fried

252

13013210, 240, 9, 0.05%, Raspberry, juice-Cooked; Canned; Cook Meth N/S 8002700, 211, 18, 0.05%, Pepper, bell-Cooked; Fresh or N/S; Baked 9010750, 240, 2, 0.05%, Cantaloupe-Cooked; Canned; Cook Meth N/S 4020850, 211, 4, 0.05%, Celery-Cooked; Fresh or N/S; Baked12002610, 130, 4, 0.05%, Peach, dried-Uncooked; Dried; Cook Meth N/S11000100, 120, 7, 0.04%, Apple, juice-Uncooked; Frozen; Cook Meth N/S 8002720, 212, 6, 0.04%, Pepper, nonbell-Cooked; Fresh or N/S; Boiled12000901, 240, 4, 0.04%, Cherry-babyfood-Cooked; Canned; Cook Meth N/S12002621, 240, 2, 0.04%, Peach, juice-babyfood-Cooked; Canned; Cook Meth N/S12000900, 240, 20, 0.04%, Cherry-Cooked; Canned; Cook Meth N/S11002670, 130, 4, 0.04%, Pear, dried-Uncooked; Dried; Cook Meth N/S11000100, 240, 17, 0.04%, Apple, juice-Cooked; Canned; Cook Meth N/S 5021940, 212, 4, 0.04%, Kale-Cooked; Fresh or N/S; Boiled11000080, 211, 3, 0.03%, Apple, peeled fruit-Cooked; Fresh or N/S; Baked11000090, 130, 4, 0.03%, Apple, dried-Uncooked; Dried; Cook Meth N/S12000900, 120, 2, 0.03%, Cherry-Uncooked; Frozen; Cook Meth N/S95001760, 120, 5, 0.03%, Grape, juice-Uncooked; Frozen; Cook Meth N/S13010550, 211, 1, 0.03%, Blackberry-Cooked; Fresh or N/S; Baked10002000, 210, 20, 0.03%, Lemon, juice-Cooked; Fresh or N/S; Cook Meth N/S10003690, 110, 4, 0.03%, Tangerine-Uncooked; Fresh or N/S; Cook Meth N/S 8002700, 240, 3, 0.03%, Pepper, bell-Cooked; Canned; Cook Meth N/S95003590, 120, 6, 0.02%, Strawberry-Uncooked; Frozen; Cook Meth N/S 5023890, 212, 1, 0.02%, Turnip, greens-Cooked; Fresh or N/S; Boiled95003601, 240, 3, 0.02%, Strawberry, juice-babyfood-Cooked; Canned; CookMeth N/S95003600, 120, 1, 0.02%, Strawberry, juice-Uncooked; Frozen; Cook Meth N/S 1033000, 212, 18, 0.02%, Potato, tuber, w/o peel-Cooked; Fresh or N/S;Boiled12002880, 110, 2, 0.02%, Plum, prune, juice-Uncooked; Fresh or N/S; CookMeth N/S12000911, 240, 3, 0.02%, Cherry, juice-babyfood-Cooked; Canned; Cook MethN/S 6010430, 213, 5, 0.02%, Bean, snap, succulent-Cooked; Fresh or N/S; Fried13020570, 210, 3, 0.02%, Blueberry-Cooked; Fresh or N/S; Cook Meth N/S11000110, 210, 2, 0.02%, Apple, sauce-Cooked; Fresh or N/S; Cook Meth N/S 4013550, 212, 8, 0.02%, Spinach-Cooked; Fresh or N/S; Boiled 5020700, 210, 6, 0.02%, Cabbage, Chinese, bok choy-Cooked; Fresh or N/S;Cook Meth N/S10002070, 110, 3, 0.02%, Lime, juice-Uncooked; Fresh or N/S; Cook Meth N/S 8002720, 240, 5, 0.02%, Pepper, nonbell-Cooked; Canned; Cook Meth N/S95002350, 210, 1, 0.02%, Olive-Cooked; Fresh or N/S; Cook Meth N/S13010580, 240, 8, 0.02%, Boysenberry-Cooked; Canned; Cook Meth N/S13021360, 110, 2, 0.02%, Currant-Uncooked; Fresh or N/S; Cook Meth N/S12002600, 211, 3, 0.02%, Peach-Cooked; Fresh or N/S; Baked10003700, 240, 10, 0.01%, Tangerine, juice-Cooked; Canned; Cook Meth N/S95002810, 240, 11, 0.01%, Pineapple, juice-Cooked; Canned; Cook Meth N/S 9013990, 110, 10, 0.01%, Watermelon-Uncooked; Fresh or N/S; Cook Meth N/S 6010430, 210, 2, 0.01%, Bean, snap, succulent-Cooked; Fresh or N/S; CookMeth N/S10002000, 130, 5, 0.01%, Lemon, juice-Uncooked; Dried; Cook Meth N/S12000120, 211, 1, 0.01%, Apricot-Cooked; Fresh or N/S; Baked11002680, 110, 3, 0.01%, Pear, juice-Uncooked; Fresh or N/S; Cook Meth N/S12002870, 130, 4, 0.01%, Plum, prune, dried-Uncooked; Dried; Cook Meth N/S95002790, 110, 5, 0.01%, Pineapple-Uncooked; Fresh or N/S; Cook Meth N/S95002810, 120, 5, 0.01%, Pineapple, juice-Uncooked; Frozen; Cook Meth N/S 8002720, 215, 3, 0.01%, Pepper, nonbell-Cooked; Fresh or N/S; Boiled/baked10002000, 240, 8, 0.01%, Lemon, juice-Cooked; Canned; Cook Meth N/S95002790, 240, 6, 0.01%, Pineapple-Cooked; Canned; Cook Meth N/S 8002720, 210, 6, 0.01%, Pepper, nonbell-Cooked; Fresh or N/S; Cook Meth N/S13021370, 130, 1, 0.01%, Currant, dried-Uncooked; Dried; Cook Meth N/S11000090, 211, 5, 0.01%, Apple, dried-Cooked; Fresh or N/S; Baked 8002700, 212, 4, 0.01%, Pepper, bell-Cooked; Fresh or N/S; Boiled12002860, 110, 1, 0.01%, Plum, prune, fresh-Uncooked; Fresh or N/S; CookMeth N/S10002000, 120, 1, 0.01%, Lemon, juice-Uncooked; Frozen; Cook Meth N/S

253

13020570, 230, 1, 0.01%, Blueberry-Cooked; Dried; Cook Meth N/S15003251, 230, 6, 0.01%, Rice, flour-babyfood-Cooked; Dried; Cook Meth N/S25002930, 213, 6, 0.01%, Pork, fat-Cooked; Fresh or N/S; Fried12002600, 210, 2, 0.01%, Peach-Cooked; Fresh or N/S; Cook Meth N/S95003600, 211, 3, 0.01%, Strawberry, juice-Cooked; Fresh or N/S; Baked13010580, 110, 1, 0.01%, Boysenberry-Uncooked; Fresh or N/S; Cook Meth N/S11000110, 221, 1, 0.01%, Apple, sauce-Cooked; Frozen; Baked 8002340, 210, 1, 0.01%, Okra-Cooked; Fresh or N/S; Cook Meth N/S11000091, 230, 2, 0.01%, Apple, dried-babyfood-Cooked; Dried; Cook Meth N/S 8001480, 214, 2, 0.01%, Eggplant-Cooked; Fresh or N/S; Fried/baked 8002700, 150, 2, 0.01%, Pepper, bell-Uncooked; Cured etc; Cook Meth N/S12000140, 110, 1, 0.00%, Apricot, juice-Uncooked; Fresh or N/S; Cook MethN/S95001760, 210, 5, 0.00%, Grape, juice-Cooked; Fresh or N/S; Cook Meth N/S10002070, 240, 3, 0.00%, Lime, juice-Cooked; Canned; Cook Meth N/S95002800, 130, 2, 0.00%, Pineapple, dried-Uncooked; Dried; Cook Meth N/S 4020850, 150, 1, 0.00%, Celery-Uncooked; Cured etc; Cook Meth N/S 1033661, 240, 4, 0.00%, Sweet potato-babyfood-Cooked; Canned; Cook Meth N/S10001800, 110, 3, 0.00%, Grapefruit-Uncooked; Fresh or N/S; Cook Meth N/S15003240, 210, 3, 0.00%, Rice, brown-Cooked; Fresh or N/S; Cook Meth N/S 1032990, 212, 3, 0.00%, Potato, tuber, w/peel-Cooked; Fresh or N/S; Boiled10003700, 110, 1, 0.00%, Tangerine, juice-Uncooked; Fresh or N/S; Cook MethN/S 8002720, 110, 1, 0.00%, Pepper, nonbell-Uncooked; Fresh or N/S; Cook MethN/S 8002730, 212, 2, 0.00%, Pepper, nonbell, dried-Cooked; Fresh or N/S; Boiled 6010430, 110, 1, 0.00%, Bean, snap, succulent-Uncooked; Fresh or N/S; CookMeth N/S12002860, 211, 1, 0.00%, Plum, prune, fresh-Cooked; Fresh or N/S; Baked 8002710, 212, 1, 0.00%, Pepper, bell, dried-Cooked; Fresh or N/S; Boiled25002930, 210, 2, 0.00%, Pork, fat-Cooked; Fresh or N/S; Cook Meth N/S15001270, 242, 3, 0.00%, Corn, sweet-Cooked; Canned; Boiled13010580, 120, 2, 0.00%, Boysenberry-Uncooked; Frozen; Cook Meth N/S13013210, 120, 2, 0.00%, Raspberry, juice-Uncooked; Frozen; Cook Meth N/S 1033000, 211, 2, 0.00%, Potato, tuber, w/o peel-Cooked; Fresh or N/S; Baked95002811, 240, 2, 0.00%, Pineapple, juice-babyfood-Cooked; Canned; Cook MethN/S10001810, 110, 2, 0.00%, Grapefruit, juice-Uncooked; Fresh or N/S; Cook MethN/S25002930, 250, 1, 0.00%, Pork, fat-Cooked; Cured etc; Cook Meth N/S 4013550, 215, 1, 0.00%, Spinach-Cooked; Fresh or N/S; Boiled/baked10001810, 240, 2, 0.00%, Grapefruit, juice-Cooked; Canned; Cook Meth N/S11000110, 240, 1, 0.00%, Apple, sauce-Cooked; Canned; Cook Meth N/S 4013551, 240, 2, 0.00%, Spinach-babyfood-Cooked; Canned; Cook Meth N/S 8003750, 215, 2, 0.00%, Tomato-Cooked; Fresh or N/S; Boiled/baked15003250, 230, 2, 0.00%, Rice, flour-Cooked; Dried; Cook Meth N/S12000910, 240, 1, 0.00%, Cherry, juice-Cooked; Canned; Cook Meth N/S15001240, 240, 1, 0.00%, Corn, field, syrup-Cooked; Canned; Cook Meth N/S 8002730, 210, 2, 0.00%, Pepper, nonbell, dried-Cooked; Fresh or N/S; CookMeth N/S 1033660, 212, 2, 0.00%, Sweet potato-Cooked; Fresh or N/S; Boiled10002000, 211, 1, 0.00%, Lemon, juice-Cooked; Fresh or N/S; Baked25002930, 242, 2, 0.00%, Pork, fat-Cooked; Canned; Boiled25002930, 230, 2, 0.00%, Pork, fat-Cooked; Dried; Cook Meth N/S 1032990, 211, 2, 0.00%, Potato, tuber, w/peel-Cooked; Fresh or N/S; Baked 4020850, 221, 1, 0.00%, Celery-Cooked; Frozen; Baked 4013550, 211, 1, 0.00%, Spinach-Cooked; Fresh or N/S; Baked12002600, 120, 1, 0.00%, Peach-Uncooked; Frozen; Cook Meth N/S12000140, 120, 1, 0.00%, Apricot, juice-Uncooked; Frozen; Cook Meth N/S95001780, 110, 1, 0.00%, Grape, raisin-Uncooked; Fresh or N/S; Cook Meth N/S 9021350, 150, 1, 0.00%, Cucumber-Uncooked; Cured etc; Cook Meth N/S11000090, 210, 1, 0.00%, Apple, dried-Cooked; Fresh or N/S; Cook Meth N/S 1034070, 110, 1, 0.00%, Yam bean-Uncooked; Fresh or N/S; Cook Meth N/S95002791, 240, 1, 0.00%, Pineapple-babyfood-Cooked; Canned; Cook Meth N/S25002930, 240, 1, 0.00%, Pork, fat-Cooked; Canned; Cook Meth N/S

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9023571, 240, 1, 0.00%, Squash, winter-babyfood-Cooked; Canned; Cook MethN/S 8002711, 240, 1, 0.00%, Pepper, bell, dried-babyfood-Cooked; Canned; CookMeth N/S 8002720, 230, 1, 0.00%, Pepper, nonbell-Cooked; Dried; Cook Meth N/S95002790, 211, 1, 0.00%, Pineapple-Cooked; Fresh or N/S; Baked10002070, 120, 1, 0.00%, Lime, juice-Uncooked; Frozen; Cook Meth N/S15003240, 232, 1, 0.00%, Rice, brown-Cooked; Dried; Boiled25002930, 221, 1, 0.00%, Pork, fat-Cooked; Frozen; Baked21000440, 211, 1, 0.00%, Beef, meat-Cooked; Fresh or N/S; Baked25002930, 253, 1, 0.00%, Pork, fat-Cooked; Cured etc; Fried 4013550, 110, 1, 0.00%, Spinach-Uncooked; Fresh or N/S; Cook Meth N/S15001241, 230, 1, 0.00%, Corn, field, syrup-babyfood-Cooked; Dried; CookMeth N/S15004020, 231, 1, 0.00%, Wheat, flour-Cooked; Dried; Baked 9021350, 212, 1, 0.00%, Cucumber-Cooked; Fresh or N/S; Boiled15003251, 240, 1, 0.00%, Rice, flour-babyfood-Cooked; Canned; Cook Meth N/S 8002720, 211, 1, 0.00%, Pepper, nonbell-Cooked; Fresh or N/S; Baked95001790, 210, 1, 0.00%, Grape, wine and sherry-Cooked; Fresh or N/S; CookMeth N/S15004020, 211, 1, 0.00%, Wheat, flour-Cooked; Fresh or N/S; Baked21000470, 211, 1, 0.00%, Beef, fat-Cooked; Fresh or N/S; Baked15001241, 130, 1, 0.00%, Corn, field, syrup-babyfood-Uncooked; Dried; CookMeth N/S

255

HispanicsLow percentile for CEC records: 95 Exposure (mg/day) = 0.005232High percentile for CEC records: 100 Exposure (mg/day) = 0.162091Number of actual records in this interval: 641

Critical foods/foodforms for this population (as derived from these records): N=number of appearances in all records (including duplicates) %=percent of total exposure for all records (including duplicates)

Food, FF, N , Percent, Food Name --------, ---, -----, -------, -------------11000070, 110, 247, 16.05%, Apple, fruit with peel-Uncooked; Fresh or N/S; CookMeth N/S95001750, 110, 103, 7.04%, Grape-Uncooked; Fresh or N/S; Cook Meth N/S13020570, 110, 63, 4.55%, Blueberry-Uncooked; Fresh or N/S; Cook Meth N/S12002300, 110, 24, 4.22%, Nectarine-Uncooked; Fresh or N/S; Cook Meth N/S 9010750, 110, 48, 4.04%, Cantaloupe-Uncooked; Fresh or N/S; Cook Meth N/S95003590, 110, 83, 3.93%, Strawberry-Uncooked; Fresh or N/S; Cook Meth N/S 4020850, 110, 64, 3.76%, Celery-Uncooked; Fresh or N/S; Cook Meth N/S 4020850, 212, 113, 3.23%, Celery-Cooked; Fresh or N/S; Boiled12002600, 110, 55, 2.77%, Peach-Uncooked; Fresh or N/S; Cook Meth N/S11002660, 110, 43, 2.42%, Pear-Uncooked; Fresh or N/S; Cook Meth N/S12002600, 240, 82, 2.42%, Peach-Cooked; Canned; Cook Meth N/S12002601, 240, 26, 2.39%, Peach-babyfood-Cooked; Canned; Cook Meth N/S95000190, 212, 4, 2.38%, Asparagus-Cooked; Fresh or N/S; Boiled13020570, 211, 28, 2.31%, Blueberry-Cooked; Fresh or N/S; Baked95000190, 242, 3, 1.90%, Asparagus-Cooked; Canned; Boiled13013200, 110, 61, 1.34%, Raspberry-Uncooked; Fresh or N/S; Cook Meth N/S10002400, 110, 93, 1.28%, Orange-Uncooked; Fresh or N/S; Cook Meth N/S11000100, 110, 135, 1.27%, Apple, juice-Uncooked; Fresh or N/S; Cook Meth N/S95002350, 240, 17, 1.27%, Olive-Cooked; Canned; Cook Meth N/S11000111, 240, 29, 1.23%, Apple, sauce-babyfood-Cooked; Canned; Cook Meth N/S13013200, 240, 35, 1.12%, Raspberry-Cooked; Canned; Cook Meth N/S11002661, 240, 15, 1.05%, Pear-babyfood-Cooked; Canned; Cook Meth N/S13020571, 240, 6, 1.00%, Blueberry-babyfood-Cooked; Canned; Cook Meth N/S 4020850, 210, 30, 0.94%, Celery-Cooked; Fresh or N/S; Cook Meth N/S 4020850, 215, 38, 0.93%, Celery-Cooked; Fresh or N/S; Boiled/baked13010561, 240, 6, 0.86%, Blackberry, juice-babyfood-Cooked; Canned; CookMeth N/S95003600, 240, 48, 0.81%, Strawberry, juice-Cooked; Canned; Cook Meth N/S 6010430, 242, 25, 0.81%, Bean, snap, succulent-Cooked; Canned; Boiled12002850, 110, 21, 0.80%, Plum-Uncooked; Fresh or N/S; Cook Meth N/S95001760, 110, 35, 0.75%, Grape, juice-Uncooked; Fresh or N/S; Cook Meth N/S95003590, 240, 35, 0.74%, Strawberry-Cooked; Canned; Cook Meth N/S 6010430, 212, 58, 0.71%, Bean, snap, succulent-Cooked; Fresh or N/S; Boiled12000130, 130, 3, 0.70%, Apricot, dried-Uncooked; Dried; Cook Meth N/S12000121, 240, 10, 0.65%, Apricot-babyfood-Cooked; Canned; Cook Meth N/S11002660, 240, 33, 0.64%, Pear-Cooked; Canned; Cook Meth N/S12002620, 110, 4, 0.63%, Peach, juice-Uncooked; Fresh or N/S; Cook Meth N/S 4020850, 242, 6, 0.59%, Celery-Cooked; Canned; Boiled12000141, 240, 11, 0.55%, Apricot, juice-babyfood-Cooked; Canned; Cook MethN/S12000120, 240, 34, 0.54%, Apricot-Cooked; Canned; Cook Meth N/S11000110, 212, 20, 0.52%, Apple, sauce-Cooked; Fresh or N/S; Boiled13010550, 240, 40, 0.50%, Blackberry-Cooked; Canned; Cook Meth N/S 9011870, 110, 6, 0.49%, Honeydew melon-Uncooked; Fresh or N/S; Cook MethN/S12002620, 240, 5, 0.47%, Peach, juice-Cooked; Canned; Cook Meth N/S13020570, 214, 5, 0.46%, Blueberry-Cooked; Fresh or N/S; Fried/baked10002410, 110, 101, 0.42%, Orange, juice-Uncooked; Fresh or N/S; Cook Meth N/S12000120, 110, 8, 0.41%, Apricot-Uncooked; Fresh or N/S; Cook Meth N/S11002681, 240, 17, 0.38%, Pear, juice-babyfood-Cooked; Canned; Cook Meth N/S11000101, 240, 34, 0.37%, Apple, juice-babyfood-Cooked; Canned; Cook Meth N/S95001760, 240, 44, 0.35%, Grape, juice-Cooked; Canned; Cook Meth N/S

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12000910, 110, 2, 0.33%, Cherry, juice-Uncooked; Fresh or N/S; Cook Meth N/S12002880, 110, 4, 0.31%, Plum, prune, juice-Uncooked; Fresh or N/S; CookMeth N/S12000140, 240, 9, 0.31%, Apricot, juice-Cooked; Canned; Cook Meth N/S 6010431, 240, 12, 0.31%, Bean, snap, succulent-babyfood-Cooked; Canned; CookMeth N/S95002350, 211, 11, 0.29%, Olive-Cooked; Fresh or N/S; Baked95002350, 212, 5, 0.26%, Olive-Cooked; Fresh or N/S; Boiled13013210, 110, 1, 0.26%, Raspberry, juice-Uncooked; Fresh or N/S; Cook MethN/S 4020850, 232, 5, 0.26%, Celery-Cooked; Dried; Boiled12002861, 240, 4, 0.25%, Plum, prune, fresh-babyfood-Cooked; Canned; CookMeth N/S 8002700, 215, 37, 0.24%, Pepper, bell-Cooked; Fresh or N/S; Boiled/baked95001750, 240, 48, 0.23%, Grape-Cooked; Canned; Cook Meth N/S95001761, 240, 20, 0.22%, Grape, juice-babyfood-Cooked; Canned; Cook Meth N/S 9010750, 240, 3, 0.21%, Cantaloupe-Cooked; Canned; Cook Meth N/S10002410, 120, 45, 0.21%, Orange, juice-Uncooked; Frozen; Cook Meth N/S 4020851, 240, 5, 0.21%, Celery-babyfood-Cooked; Canned; Cook Meth N/S95003600, 110, 3, 0.20%, Strawberry, juice-Uncooked; Fresh or N/S; Cook MethN/S 8002700, 210, 16, 0.20%, Pepper, bell-Cooked; Fresh or N/S; Cook Meth N/S11000081, 240, 8, 0.17%, Apple, peeled fruit-babyfood-Cooked; Canned; CookMeth N/S13013211, 240, 6, 0.17%, Raspberry, juice-babyfood-Cooked; Canned; Cook MethN/S13020570, 120, 11, 0.16%, Blueberry-Uncooked; Frozen; Cook Meth N/S 8002700, 110, 22, 0.16%, Pepper, bell-Uncooked; Fresh or N/S; Cook Meth N/S12000900, 110, 25, 0.15%, Cherry-Uncooked; Fresh or N/S; Cook Meth N/S12000900, 240, 22, 0.15%, Cherry-Cooked; Canned; Cook Meth N/S13020570, 213, 4, 0.14%, Blueberry-Cooked; Fresh or N/S; Fried 9021350, 110, 19, 0.13%, Cucumber-Uncooked; Fresh or N/S; Cook Meth N/S10002000, 110, 17, 0.13%, Lemon, juice-Uncooked; Fresh or N/S; Cook Meth N/S 9021350, 240, 29, 0.13%, Cucumber-Cooked; Canned; Cook Meth N/S11002680, 240, 6, 0.12%, Pear, juice-Cooked; Canned; Cook Meth N/S95002810, 110, 14, 0.12%, Pineapple, juice-Uncooked; Fresh or N/S; Cook MethN/S 5021170, 212, 1, 0.11%, Collards-Cooked; Fresh or N/S; Boiled11000100, 240, 25, 0.11%, Apple, juice-Cooked; Canned; Cook Meth N/S 8002720, 212, 11, 0.11%, Pepper, nonbell-Cooked; Fresh or N/S; Boiled12002621, 240, 4, 0.10%, Peach, juice-babyfood-Cooked; Canned; Cook Meth N/S13020570, 240, 14, 0.10%, Blueberry-Cooked; Canned; Cook Meth N/S 6010430, 222, 6, 0.10%, Bean, snap, succulent-Cooked; Frozen; Boiled95003600, 210, 16, 0.09%, Strawberry, juice-Cooked; Fresh or N/S; Cook MethN/S95002350, 210, 3, 0.09%, Olive-Cooked; Fresh or N/S; Cook Meth N/S 8002700, 213, 9, 0.09%, Pepper, bell-Cooked; Fresh or N/S; Fried12000910, 210, 16, 0.08%, Cherry, juice-Cooked; Fresh or N/S; Cook Meth N/S95001750, 210, 16, 0.08%, Grape-Cooked; Fresh or N/S; Cook Meth N/S95003601, 240, 6, 0.07%, Strawberry, juice-babyfood-Cooked; Canned; CookMeth N/S11002660, 210, 16, 0.07%, Pear-Cooked; Fresh or N/S; Cook Meth N/S13013201, 240, 5, 0.07%, Raspberry-babyfood-Cooked; Canned; Cook Meth N/S 1033000, 212, 29, 0.07%, Potato, tuber, w/o peel-Cooked; Fresh or N/S;Boiled12000901, 240, 3, 0.06%, Cherry-babyfood-Cooked; Canned; Cook Meth N/S12002851, 240, 5, 0.05%, Plum-babyfood-Cooked; Canned; Cook Meth N/S95002810, 240, 16, 0.05%, Pineapple, juice-Cooked; Canned; Cook Meth N/S 4013550, 212, 5, 0.05%, Spinach-Cooked; Fresh or N/S; Boiled 8002700, 212, 9, 0.05%, Pepper, bell-Cooked; Fresh or N/S; Boiled 8002700, 240, 3, 0.05%, Pepper, bell-Cooked; Canned; Cook Meth N/S 8002700, 211, 11, 0.05%, Pepper, bell-Cooked; Fresh or N/S; Baked95001780, 130, 13, 0.05%, Grape, raisin-Uncooked; Dried; Cook Meth N/S95003590, 211, 4, 0.04%, Strawberry-Cooked; Fresh or N/S; Baked 4020850, 211, 2, 0.04%, Celery-Cooked; Fresh or N/S; Baked

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10001810, 120, 3, 0.04%, Grapefruit, juice-Uncooked; Frozen; Cook Meth N/S95001760, 120, 2, 0.04%, Grape, juice-Uncooked; Frozen; Cook Meth N/S13013200, 120, 4, 0.03%, Raspberry-Uncooked; Frozen; Cook Meth N/S 5020700, 210, 3, 0.03%, Cabbage, Chinese, bok choy-Cooked; Fresh or N/S;Cook Meth N/S12000900, 211, 2, 0.03%, Cherry-Cooked; Fresh or N/S; Baked10003700, 240, 10, 0.03%, Tangerine, juice-Cooked; Canned; Cook Meth N/S 9013990, 110, 10, 0.03%, Watermelon-Uncooked; Fresh or N/S; Cook Meth N/S10002070, 110, 1, 0.03%, Lime, juice-Uncooked; Fresh or N/S; Cook Meth N/S12002610, 130, 2, 0.03%, Peach, dried-Uncooked; Dried; Cook Meth N/S13013210, 240, 6, 0.03%, Raspberry, juice-Cooked; Canned; Cook Meth N/S13010580, 240, 6, 0.03%, Boysenberry-Cooked; Canned; Cook Meth N/S10001810, 110, 6, 0.02%, Grapefruit, juice-Uncooked; Fresh or N/S; Cook MethN/S 8002720, 240, 2, 0.02%, Pepper, nonbell-Cooked; Canned; Cook Meth N/S10002000, 240, 9, 0.02%, Lemon, juice-Cooked; Canned; Cook Meth N/S10003690, 110, 2, 0.02%, Tangerine-Uncooked; Fresh or N/S; Cook Meth N/S11000110, 210, 1, 0.02%, Apple, sauce-Cooked; Fresh or N/S; Cook Meth N/S15003251, 230, 9, 0.02%, Rice, flour-babyfood-Cooked; Dried; Cook Meth N/S13020570, 230, 1, 0.02%, Blueberry-Cooked; Dried; Cook Meth N/S10001990, 110, 4, 0.02%, Lemon-Uncooked; Fresh or N/S; Cook Meth N/S12002860, 110, 1, 0.02%, Plum, prune, fresh-Uncooked; Fresh or N/S; CookMeth N/S 6010430, 210, 2, 0.02%, Bean, snap, succulent-Cooked; Fresh or N/S; CookMeth N/S 8002720, 210, 6, 0.02%, Pepper, nonbell-Cooked; Fresh or N/S; Cook Meth N/S 1032990, 212, 7, 0.01%, Potato, tuber, w/peel-Cooked; Fresh or N/S; Boiled10002411, 240, 4, 0.01%, Orange, juice-babyfood-Cooked; Canned; Cook MethN/S10002070, 240, 6, 0.01%, Lime, juice-Cooked; Canned; Cook Meth N/S13020570, 210, 1, 0.01%, Blueberry-Cooked; Fresh or N/S; Cook Meth N/S 8002720, 213, 1, 0.01%, Pepper, nonbell-Cooked; Fresh or N/S; Fried11000080, 110, 1, 0.01%, Apple, peeled fruit-Uncooked; Fresh or N/S; CookMeth N/S15003250, 230, 8, 0.01%, Rice, flour-Cooked; Dried; Cook Meth N/S 9020880, 210, 1, 0.01%, Chayote, fruit-Cooked; Fresh or N/S; Cook Meth N/S11000080, 211, 1, 0.01%, Apple, peeled fruit-Cooked; Fresh or N/S; Baked95002790, 240, 6, 0.01%, Pineapple-Cooked; Canned; Cook Meth N/S25002930, 210, 7, 0.01%, Pork, fat-Cooked; Fresh or N/S; Cook Meth N/S95002790, 110, 4, 0.01%, Pineapple-Uncooked; Fresh or N/S; Cook Meth N/S10002000, 210, 8, 0.01%, Lemon, juice-Cooked; Fresh or N/S; Cook Meth N/S95003590, 120, 4, 0.01%, Strawberry-Uncooked; Frozen; Cook Meth N/S11000091, 230, 3, 0.01%, Apple, dried-babyfood-Cooked; Dried; Cook Meth N/S11000090, 211, 2, 0.01%, Apple, dried-Cooked; Fresh or N/S; Baked10002000, 130, 2, 0.01%, Lemon, juice-Uncooked; Dried; Cook Meth N/S25002930, 213, 5, 0.01%, Pork, fat-Cooked; Fresh or N/S; Fried10002410, 240, 4, 0.01%, Orange, juice-Cooked; Canned; Cook Meth N/S 8002720, 215, 5, 0.01%, Pepper, nonbell-Cooked; Fresh or N/S; Boiled/baked 8003750, 215, 5, 0.01%, Tomato-Cooked; Fresh or N/S; Boiled/baked13013200, 211, 3, 0.01%, Raspberry-Cooked; Fresh or N/S; Baked 8002730, 210, 5, 0.01%, Pepper, nonbell, dried-Cooked; Fresh or N/S; CookMeth N/S12002600, 210, 1, 0.01%, Peach-Cooked; Fresh or N/S; Cook Meth N/S12002600, 120, 4, 0.01%, Peach-Uncooked; Frozen; Cook Meth N/S12000900, 120, 3, 0.01%, Cherry-Uncooked; Frozen; Cook Meth N/S95002810, 120, 2, 0.01%, Pineapple, juice-Uncooked; Frozen; Cook Meth N/S12002881, 240, 1, 0.01%, Plum, prune, juice-babyfood-Cooked; Canned; CookMeth N/S11000090, 230, 2, 0.01%, Apple, dried-Cooked; Dried; Cook Meth N/S 4020850, 213, 1, 0.01%, Celery-Cooked; Fresh or N/S; Fried 4013551, 240, 3, 0.01%, Spinach-babyfood-Cooked; Canned; Cook Meth N/S12000910, 240, 2, 0.01%, Cherry, juice-Cooked; Canned; Cook Meth N/S95001780, 211, 3, 0.01%, Grape, raisin-Cooked; Fresh or N/S; Baked 8002730, 212, 4, 0.01%, Pepper, nonbell, dried-Cooked; Fresh or N/S; Boiled11000090, 130, 1, 0.01%, Apple, dried-Uncooked; Dried; Cook Meth N/S

258

8001480, 215, 1, 0.01%, Eggplant-Cooked; Fresh or N/S; Boiled/baked11002670, 130, 1, 0.01%, Pear, dried-Uncooked; Dried; Cook Meth N/S13013210, 120, 2, 0.01%, Raspberry, juice-Uncooked; Frozen; Cook Meth N/S13010550, 120, 2, 0.01%, Blackberry-Uncooked; Frozen; Cook Meth N/S13010580, 120, 2, 0.01%, Boysenberry-Uncooked; Frozen; Cook Meth N/S 8003770, 240, 4, 0.01%, Tomato, puree-Cooked; Canned; Cook Meth N/S25002930, 230, 3, 0.00%, Pork, fat-Cooked; Dried; Cook Meth N/S10002060, 110, 1, 0.00%, Lime-Uncooked; Fresh or N/S; Cook Meth N/S95001790, 110, 2, 0.00%, Grape, wine and sherry-Uncooked; Fresh or N/S; CookMeth N/S 8002720, 110, 2, 0.00%, Pepper, nonbell-Uncooked; Fresh or N/S; Cook MethN/S10001800, 110, 1, 0.00%, Grapefruit-Uncooked; Fresh or N/S; Cook Meth N/S 8002700, 150, 1, 0.00%, Pepper, bell-Uncooked; Cured etc; Cook Meth N/S12000140, 120, 2, 0.00%, Apricot, juice-Uncooked; Frozen; Cook Meth N/S10001810, 240, 2, 0.00%, Grapefruit, juice-Cooked; Canned; Cook Meth N/S25002930, 250, 1, 0.00%, Pork, fat-Cooked; Cured etc; Cook Meth N/S95002811, 240, 2, 0.00%, Pineapple, juice-babyfood-Cooked; Canned; Cook MethN/S 8003770, 210, 2, 0.00%, Tomato, puree-Cooked; Fresh or N/S; Cook Meth N/S25002930, 211, 2, 0.00%, Pork, fat-Cooked; Fresh or N/S; Baked10002070, 120, 2, 0.00%, Lime, juice-Uncooked; Frozen; Cook Meth N/S15001240, 240, 3, 0.00%, Corn, field, syrup-Cooked; Canned; Cook Meth N/S 8003790, 212, 2, 0.00%, Tomato, juice-Cooked; Fresh or N/S; Boiled11000110, 240, 1, 0.00%, Apple, sauce-Cooked; Canned; Cook Meth N/S15003240, 232, 1, 0.00%, Rice, brown-Cooked; Dried; Boiled95002800, 130, 1, 0.00%, Pineapple, dried-Uncooked; Dried; Cook Meth N/S 8002720, 211, 2, 0.00%, Pepper, nonbell-Cooked; Fresh or N/S; Baked 1010790, 110, 2, 0.00%, Carrot, juice-Uncooked; Fresh or N/S; Cook Meth N/S95001780, 110, 1, 0.00%, Grape, raisin-Uncooked; Fresh or N/S; Cook Meth N/S11000110, 211, 1, 0.00%, Apple, sauce-Cooked; Fresh or N/S; Baked 1034070, 110, 1, 0.00%, Yam bean-Uncooked; Fresh or N/S; Cook Meth N/S25002930, 253, 2, 0.00%, Pork, fat-Cooked; Cured etc; Fried95002360, 900, 2, 0.00%, Olive, oil-Refined; FF N/A; Cook Meth N/S12002870, 130, 1, 0.00%, Plum, prune, dried-Uncooked; Dried; Cook Meth N/S25002930, 240, 1, 0.00%, Pork, fat-Cooked; Canned; Cook Meth N/S 9014000, 110, 1, 0.00%, Watermelon, juice-Uncooked; Fresh or N/S; Cook MethN/S10003700, 120, 1, 0.00%, Tangerine, juice-Uncooked; Frozen; Cook Meth N/S12000911, 240, 1, 0.00%, Cherry, juice-babyfood-Cooked; Canned; Cook MethN/S11002680, 120, 1, 0.00%, Pear, juice-Uncooked; Frozen; Cook Meth N/S10002000, 120, 1, 0.00%, Lemon, juice-Uncooked; Frozen; Cook Meth N/S 1010780, 212, 1, 0.00%, Carrot-Cooked; Fresh or N/S; Boiled 1033661, 240, 1, 0.00%, Sweet potato-babyfood-Cooked; Canned; Cook Meth N/S 1032990, 211, 1, 0.00%, Potato, tuber, w/peel-Cooked; Fresh or N/S; Baked 8003750, 212, 1, 0.00%, Tomato-Cooked; Fresh or N/S; Boiled15003251, 240, 1, 0.00%, Rice, flour-babyfood-Cooked; Canned; Cook Meth N/S12000910, 120, 1, 0.00%, Cherry, juice-Uncooked; Frozen; Cook Meth N/S11000100, 120, 1, 0.00%, Apple, juice-Uncooked; Frozen; Cook Meth N/S95003600, 120, 1, 0.00%, Strawberry, juice-Uncooked; Frozen; Cook Meth N/S 1010781, 240, 1, 0.00%, Carrot-babyfood-Cooked; Canned; Cook Meth N/S15001271, 240, 1, 0.00%, Corn, sweet-babyfood-Cooked; Canned; Cook Meth N/S25002900, 211, 1, 0.00%, Pork, meat-Cooked; Fresh or N/S; Baked 8003770, 232, 1, 0.00%, Tomato, puree-Cooked; Dried; Boiled 8003770, 212, 1, 0.00%, Tomato, puree-Cooked; Fresh or N/S; Boiled15001270, 212, 1, 0.00%, Corn, sweet-Cooked; Fresh or N/S; Boiled 9023560, 212, 1, 0.00%, Squash, summer-Cooked; Fresh or N/S; Boiled10002000, 211, 1, 0.00%, Lemon, juice-Cooked; Fresh or N/S; Baked

259

Non-hispanic whitesLow percentile for CEC records: 95 Exposure (mg/day) = 0.006422High percentile for CEC records: 100 Exposure (mg/day) = 0.238165Number of actual records in this interval: 2792

Critical foods/foodforms for this population (as derived from these records): N=number of appearances in all records (including duplicates) %=percent of total exposure for all records (including duplicates)

Food, FF, N , Percent, Food Name --------, ---, -----, -------, -------------95000190, 212, 128, 9.57%, Asparagus-Cooked; Fresh or N/S; Boiled11000070, 110, 771, 7.25%, Apple, fruit with peel-Uncooked; Fresh or N/S; CookMeth N/S13020570, 110, 387, 6.71%, Blueberry-Uncooked; Fresh or N/S; Cook Meth N/S95000190, 242, 58, 6.51%, Asparagus-Cooked; Canned; Boiled13020570, 211, 352, 4.69%, Blueberry-Cooked; Fresh or N/S; Baked95002350, 240, 185, 4.30%, Olive-Cooked; Canned; Cook Meth N/S95001750, 110, 404, 3.71%, Grape-Uncooked; Fresh or N/S; Cook Meth N/S95003590, 110, 374, 3.49%, Strawberry-Uncooked; Fresh or N/S; Cook Meth N/S13020571, 240, 67, 3.43%, Blueberry-babyfood-Cooked; Canned; Cook Meth N/S 9010750, 110, 273, 2.90%, Cantaloupe-Uncooked; Fresh or N/S; Cook Meth N/S12002601, 240, 163, 2.62%, Peach-babyfood-Cooked; Canned; Cook Meth N/S12002600, 240, 398, 2.36%, Peach-Cooked; Canned; Cook Meth N/S 4020850, 110, 320, 2.26%, Celery-Uncooked; Fresh or N/S; Cook Meth N/S12002300, 110, 81, 1.69%, Nectarine-Uncooked; Fresh or N/S; Cook Meth N/S13013200, 240, 275, 1.60%, Raspberry-Cooked; Canned; Cook Meth N/S13020570, 120, 71, 1.56%, Blueberry-Uncooked; Frozen; Cook Meth N/S11002661, 240, 144, 1.51%, Pear-babyfood-Cooked; Canned; Cook Meth N/S95003600, 240, 346, 1.40%, Strawberry, juice-Cooked; Canned; Cook Meth N/S 6010430, 242, 221, 1.33%, Bean, snap, succulent-Cooked; Canned; Boiled11000110, 212, 236, 1.31%, Apple, sauce-Cooked; Fresh or N/S; Boiled11000111, 240, 193, 1.20%, Apple, sauce-babyfood-Cooked; Canned; Cook Meth N/S12002600, 110, 185, 1.15%, Peach-Uncooked; Fresh or N/S; Cook Meth N/S12000121, 240, 67, 1.10%, Apricot-babyfood-Cooked; Canned; Cook Meth N/S95003590, 240, 263, 1.04%, Strawberry-Cooked; Canned; Cook Meth N/S13020570, 214, 61, 0.97%, Blueberry-Cooked; Fresh or N/S; Fried/baked11000100, 110, 558, 0.94%, Apple, juice-Uncooked; Fresh or N/S; Cook Meth N/S11002660, 110, 109, 0.90%, Pear-Uncooked; Fresh or N/S; Cook Meth N/S11002660, 240, 146, 0.81%, Pear-Cooked; Canned; Cook Meth N/S 4020850, 212, 227, 0.79%, Celery-Cooked; Fresh or N/S; Boiled95000190, 222, 17, 0.78%, Asparagus-Cooked; Frozen; Boiled13013200, 110, 260, 0.77%, Raspberry-Uncooked; Fresh or N/S; Cook Meth N/S 6010431, 240, 116, 0.76%, Bean, snap, succulent-babyfood-Cooked; Canned; CookMeth N/S95001760, 110, 171, 0.73%, Grape, juice-Uncooked; Fresh or N/S; Cook Meth N/S11000081, 240, 131, 0.64%, Apple, peeled fruit-babyfood-Cooked; Canned; CookMeth N/S13010550, 240, 253, 0.63%, Blackberry-Cooked; Canned; Cook Meth N/S12000120, 240, 252, 0.62%, Apricot-Cooked; Canned; Cook Meth N/S13013210, 110, 20, 0.61%, Raspberry, juice-Uncooked; Fresh or N/S; Cook MethN/S12000141, 240, 48, 0.57%, Apricot, juice-babyfood-Cooked; Canned; Cook MethN/S 6010430, 212, 157, 0.53%, Bean, snap, succulent-Cooked; Fresh or N/S; Boiled95001760, 240, 363, 0.50%, Grape, juice-Cooked; Canned; Cook Meth N/S 9011870, 110, 50, 0.43%, Honeydew melon-Uncooked; Fresh or N/S; Cook MethN/S 4020850, 210, 115, 0.39%, Celery-Cooked; Fresh or N/S; Cook Meth N/S12000130, 130, 15, 0.38%, Apricot, dried-Uncooked; Dried; Cook Meth N/S13013200, 120, 37, 0.37%, Raspberry-Uncooked; Frozen; Cook Meth N/S12002850, 110, 54, 0.36%, Plum-Uncooked; Fresh or N/S; Cook Meth N/S95003600, 210, 171, 0.29%, Strawberry, juice-Cooked; Fresh or N/S; Cook MethN/S

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11002681, 240, 47, 0.27%, Pear, juice-babyfood-Cooked; Canned; Cook Meth N/S12002851, 240, 41, 0.26%, Plum-babyfood-Cooked; Canned; Cook Meth N/S12000910, 210, 169, 0.25%, Cherry, juice-Cooked; Fresh or N/S; Cook Meth N/S 4020850, 242, 20, 0.25%, Celery-Cooked; Canned; Boiled95002350, 211, 56, 0.24%, Olive-Cooked; Fresh or N/S; Baked10002400, 110, 138, 0.24%, Orange-Uncooked; Fresh or N/S; Cook Meth N/S95001750, 210, 169, 0.24%, Grape-Cooked; Fresh or N/S; Cook Meth N/S13013201, 240, 61, 0.23%, Raspberry-babyfood-Cooked; Canned; Cook Meth N/S11002660, 210, 169, 0.22%, Pear-Cooked; Fresh or N/S; Cook Meth N/S 8002700, 110, 107, 0.22%, Pepper, bell-Uncooked; Fresh or N/S; Cook Meth N/S95003590, 120, 20, 0.22%, Strawberry-Uncooked; Frozen; Cook Meth N/S 9021350, 110, 136, 0.21%, Cucumber-Uncooked; Fresh or N/S; Cook Meth N/S12000910, 110, 9, 0.20%, Cherry, juice-Uncooked; Fresh or N/S; Cook Meth N/S 6010430, 222, 47, 0.20%, Bean, snap, succulent-Cooked; Frozen; Boiled10002410, 110, 264, 0.18%, Orange, juice-Uncooked; Fresh or N/S; Cook Meth N/S12000900, 110, 99, 0.17%, Cherry-Uncooked; Fresh or N/S; Cook Meth N/S13010561, 240, 7, 0.17%, Blackberry, juice-babyfood-Cooked; Canned; CookMeth N/S95001750, 240, 221, 0.17%, Grape-Cooked; Canned; Cook Meth N/S13020570, 213, 21, 0.17%, Blueberry-Cooked; Fresh or N/S; Fried 4023220, 240, 6, 0.16%, Rhubarb-Cooked; Canned; Cook Meth N/S11000101, 240, 106, 0.16%, Apple, juice-babyfood-Cooked; Canned; Cook Meth N/S12002861, 240, 17, 0.16%, Plum, prune, fresh-babyfood-Cooked; Canned; CookMeth N/S13021910, 110, 1, 0.15%, Huckleberry-Uncooked; Fresh or N/S; Cook Meth N/S12002880, 110, 15, 0.15%, Plum, prune, juice-Uncooked; Fresh or N/S; CookMeth N/S 8002700, 210, 51, 0.14%, Pepper, bell-Cooked; Fresh or N/S; Cook Meth N/S13013200, 211, 85, 0.14%, Raspberry-Cooked; Fresh or N/S; Baked 5023890, 212, 8, 0.14%, Turnip, greens-Cooked; Fresh or N/S; Boiled11000100, 240, 168, 0.14%, Apple, juice-Cooked; Canned; Cook Meth N/S12000120, 110, 11, 0.13%, Apricot-Uncooked; Fresh or N/S; Cook Meth N/S95003600, 110, 12, 0.12%, Strawberry, juice-Uncooked; Fresh or N/S; Cook MethN/S13010550, 110, 12, 0.12%, Blackberry-Uncooked; Fresh or N/S; Cook Meth N/S12002610, 130, 6, 0.11%, Peach, dried-Uncooked; Dried; Cook Meth N/S13020570, 240, 56, 0.11%, Blueberry-Cooked; Canned; Cook Meth N/S 9021350, 240, 90, 0.11%, Cucumber-Cooked; Canned; Cook Meth N/S13010550, 211, 5, 0.11%, Blackberry-Cooked; Fresh or N/S; Baked 4020851, 240, 19, 0.10%, Celery-babyfood-Cooked; Canned; Cook Meth N/S13020570, 210, 22, 0.10%, Blueberry-Cooked; Fresh or N/S; Cook Meth N/S10002410, 120, 142, 0.09%, Orange, juice-Uncooked; Frozen; Cook Meth N/S95001780, 130, 102, 0.09%, Grape, raisin-Uncooked; Dried; Cook Meth N/S 5021170, 212, 6, 0.09%, Collards-Cooked; Fresh or N/S; Boiled95003590, 211, 80, 0.08%, Strawberry-Cooked; Fresh or N/S; Baked 4020850, 232, 11, 0.08%, Celery-Cooked; Dried; Boiled95001761, 240, 39, 0.08%, Grape, juice-babyfood-Cooked; Canned; Cook Meth N/S12000130, 211, 24, 0.08%, Apricot, dried-Cooked; Fresh or N/S; Baked10002000, 110, 67, 0.08%, Lemon, juice-Uncooked; Fresh or N/S; Cook Meth N/S13010550, 120, 12, 0.08%, Blackberry-Uncooked; Frozen; Cook Meth N/S13013210, 120, 11, 0.08%, Raspberry, juice-Uncooked; Frozen; Cook Meth N/S 4023670, 212, 4, 0.07%, Swiss chard-Cooked; Fresh or N/S; Boiled12000901, 240, 16, 0.07%, Cherry-babyfood-Cooked; Canned; Cook Meth N/S12000900, 240, 65, 0.06%, Cherry-Cooked; Canned; Cook Meth N/S 4023220, 211, 5, 0.06%, Rhubarb-Cooked; Fresh or N/S; Baked95002810, 240, 107, 0.05%, Pineapple, juice-Cooked; Canned; Cook Meth N/S95000190, 110, 2, 0.05%, Asparagus-Uncooked; Fresh or N/S; Cook Meth N/S 4020850, 240, 8, 0.05%, Celery-Cooked; Canned; Cook Meth N/S 8002700, 211, 57, 0.05%, Pepper, bell-Cooked; Fresh or N/S; Baked11002680, 240, 44, 0.05%, Pear, juice-Cooked; Canned; Cook Meth N/S11000070, 211, 7, 0.05%, Apple, fruit with peel-Cooked; Fresh or N/S; Baked11000080, 211, 17, 0.05%, Apple, peeled fruit-Cooked; Fresh or N/S; Baked95001790, 110, 44, 0.05%, Grape, wine and sherry-Uncooked; Fresh or N/S; CookMeth N/S95001760, 120, 12, 0.05%, Grape, juice-Uncooked; Frozen; Cook Meth N/S

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12000911, 240, 16, 0.05%, Cherry, juice-babyfood-Cooked; Canned; Cook MethN/S 1033000, 212, 106, 0.05%, Potato, tuber, w/o peel-Cooked; Fresh or N/S;Boiled10001810, 110, 20, 0.04%, Grapefruit, juice-Uncooked; Fresh or N/S; Cook MethN/S95002810, 110, 26, 0.04%, Pineapple, juice-Uncooked; Fresh or N/S; Cook MethN/S10003690, 110, 18, 0.04%, Tangerine-Uncooked; Fresh or N/S; Cook Meth N/S 5023890, 222, 1, 0.04%, Turnip, greens-Cooked; Frozen; Boiled 6010430, 110, 6, 0.04%, Bean, snap, succulent-Uncooked; Fresh or N/S; CookMeth N/S12000140, 240, 15, 0.04%, Apricot, juice-Cooked; Canned; Cook Meth N/S12000900, 211, 17, 0.04%, Cherry-Cooked; Fresh or N/S; Baked11000090, 130, 8, 0.04%, Apple, dried-Uncooked; Dried; Cook Meth N/S10002000, 210, 82, 0.04%, Lemon, juice-Cooked; Fresh or N/S; Cook Meth N/S 4020850, 211, 11, 0.04%, Celery-Cooked; Fresh or N/S; Baked11000110, 210, 8, 0.04%, Apple, sauce-Cooked; Fresh or N/S; Cook Meth N/S95002790, 240, 35, 0.04%, Pineapple-Cooked; Canned; Cook Meth N/S13013210, 240, 16, 0.04%, Raspberry, juice-Cooked; Canned; Cook Meth N/S11000080, 240, 7, 0.04%, Apple, peeled fruit-Cooked; Canned; Cook Meth N/S11000100, 120, 19, 0.03%, Apple, juice-Uncooked; Frozen; Cook Meth N/S13013211, 240, 7, 0.03%, Raspberry, juice-babyfood-Cooked; Canned; Cook MethN/S 8002340, 210, 4, 0.03%, Okra-Cooked; Fresh or N/S; Cook Meth N/S12000120, 232, 1, 0.03%, Apricot-Cooked; Dried; Boiled10003700, 240, 23, 0.03%, Tangerine, juice-Cooked; Canned; Cook Meth N/S 9010800, 110, 1, 0.03%, Casaba-Uncooked; Fresh or N/S; Cook Meth N/S12000900, 120, 9, 0.03%, Cherry-Uncooked; Frozen; Cook Meth N/S95002350, 215, 1, 0.02%, Olive-Cooked; Fresh or N/S; Boiled/baked12002881, 240, 5, 0.02%, Plum, prune, juice-babyfood-Cooked; Canned; CookMeth N/S13020570, 230, 4, 0.02%, Blueberry-Cooked; Dried; Cook Meth N/S10002000, 130, 34, 0.02%, Lemon, juice-Uncooked; Dried; Cook Meth N/S 4020850, 215, 11, 0.02%, Celery-Cooked; Fresh or N/S; Boiled/baked 6010430, 210, 6, 0.02%, Bean, snap, succulent-Cooked; Fresh or N/S; CookMeth N/S11002670, 130, 6, 0.02%, Pear, dried-Uncooked; Dried; Cook Meth N/S11000090, 211, 27, 0.02%, Apple, dried-Cooked; Fresh or N/S; Baked 8002700, 212, 8, 0.02%, Pepper, bell-Cooked; Fresh or N/S; Boiled12002600, 211, 10, 0.02%, Peach-Cooked; Fresh or N/S; Baked 5022290, 212, 2, 0.02%, Mustard greens-Cooked; Fresh or N/S; Boiled95003601, 240, 7, 0.01%, Strawberry, juice-babyfood-Cooked; Canned; CookMeth N/S13010580, 120, 12, 0.01%, Boysenberry-Uncooked; Frozen; Cook Meth N/S12002870, 130, 11, 0.01%, Plum, prune, dried-Uncooked; Dried; Cook Meth N/S 5021170, 242, 1, 0.01%, Collards-Cooked; Canned; Boiled 5023890, 242, 2, 0.01%, Turnip, greens-Cooked; Canned; Boiled95002350, 210, 3, 0.01%, Olive-Cooked; Fresh or N/S; Cook Meth N/S11002680, 110, 7, 0.01%, Pear, juice-Uncooked; Fresh or N/S; Cook Meth N/S12002600, 210, 9, 0.01%, Peach-Cooked; Fresh or N/S; Cook Meth N/S15003251, 230, 27, 0.01%, Rice, flour-babyfood-Cooked; Dried; Cook Meth N/S 9013990, 110, 29, 0.01%, Watermelon-Uncooked; Fresh or N/S; Cook Meth N/S 8002700, 213, 13, 0.01%, Pepper, bell-Cooked; Fresh or N/S; Fried12000120, 211, 2, 0.01%, Apricot-Cooked; Fresh or N/S; Baked95002811, 240, 23, 0.01%, Pineapple, juice-babyfood-Cooked; Canned; Cook MethN/S 4020860, 110, 2, 0.01%, Celery, juice-Uncooked; Fresh or N/S; Cook Meth N/S12000140, 110, 3, 0.01%, Apricot, juice-Uncooked; Fresh or N/S; Cook MethN/S12002600, 120, 7, 0.01%, Peach-Uncooked; Frozen; Cook Meth N/S95001760, 210, 30, 0.01%, Grape, juice-Cooked; Fresh or N/S; Cook Meth N/S 5021940, 212, 7, 0.01%, Kale-Cooked; Fresh or N/S; Boiled 5020700, 210, 7, 0.01%, Cabbage, Chinese, bok choy-Cooked; Fresh or N/S;Cook Meth N/S

262

5022290, 242, 1, 0.01%, Mustard greens-Cooked; Canned; Boiled10002000, 240, 17, 0.01%, Lemon, juice-Cooked; Canned; Cook Meth N/S 4013550, 222, 5, 0.01%, Spinach-Cooked; Frozen; Boiled10002070, 240, 15, 0.01%, Lime, juice-Cooked; Canned; Cook Meth N/S 5021940, 242, 1, 0.01%, Kale-Cooked; Canned; Boiled10001800, 110, 20, 0.01%, Grapefruit-Uncooked; Fresh or N/S; Cook Meth N/S12002620, 110, 1, 0.01%, Peach, juice-Uncooked; Fresh or N/S; Cook Meth N/S 4020850, 214, 1, 0.01%, Celery-Cooked; Fresh or N/S; Fried/baked13010580, 110, 2, 0.01%, Boysenberry-Uncooked; Fresh or N/S; Cook Meth N/S95002790, 110, 11, 0.01%, Pineapple-Uncooked; Fresh or N/S; Cook Meth N/S 6010430, 215, 2, 0.01%, Bean, snap, succulent-Cooked; Fresh or N/S;Boiled/baked95002810, 120, 8, 0.01%, Pineapple, juice-Uncooked; Frozen; Cook Meth N/S12002621, 240, 3, 0.01%, Peach, juice-babyfood-Cooked; Canned; Cook Meth N/S 8001480, 214, 6, 0.01%, Eggplant-Cooked; Fresh or N/S; Fried/baked10002070, 110, 8, 0.01%, Lime, juice-Uncooked; Fresh or N/S; Cook Meth N/S13010580, 240, 14, 0.01%, Boysenberry-Cooked; Canned; Cook Meth N/S 8002720, 240, 8, 0.01%, Pepper, nonbell-Cooked; Canned; Cook Meth N/S10002000, 120, 5, 0.01%, Lemon, juice-Uncooked; Frozen; Cook Meth N/S 1033661, 240, 21, 0.01%, Sweet potato-babyfood-Cooked; Canned; Cook Meth N/S10002410, 240, 16, 0.01%, Orange, juice-Cooked; Canned; Cook Meth N/S 8002720, 110, 3, 0.01%, Pepper, nonbell-Uncooked; Fresh or N/S; Cook MethN/S 8002340, 213, 4, 0.01%, Okra-Cooked; Fresh or N/S; Fried 1032990, 212, 12, 0.01%, Potato, tuber, w/peel-Cooked; Fresh or N/S; Boiled 8002720, 210, 7, 0.01%, Pepper, nonbell-Cooked; Fresh or N/S; Cook Meth N/S25002930, 210, 13, 0.01%, Pork, fat-Cooked; Fresh or N/S; Cook Meth N/S13021360, 110, 2, 0.01%, Currant-Uncooked; Fresh or N/S; Cook Meth N/S 4020850, 213, 4, 0.01%, Celery-Cooked; Fresh or N/S; Fried 8002700, 215, 9, 0.00%, Pepper, bell-Cooked; Fresh or N/S; Boiled/baked 6010430, 213, 5, 0.00%, Bean, snap, succulent-Cooked; Fresh or N/S; Fried11000070, 213, 1, 0.00%, Apple, fruit with peel-Cooked; Fresh or N/S; Fried10001810, 120, 1, 0.00%, Grapefruit, juice-Uncooked; Frozen; Cook Meth N/S 4013550, 212, 6, 0.00%, Spinach-Cooked; Fresh or N/S; Boiled 8002700, 240, 7, 0.00%, Pepper, bell-Cooked; Canned; Cook Meth N/S 8002730, 212, 10, 0.00%, Pepper, nonbell, dried-Cooked; Fresh or N/S; Boiled10001810, 240, 8, 0.00%, Grapefruit, juice-Cooked; Canned; Cook Meth N/S11000090, 230, 8, 0.00%, Apple, dried-Cooked; Dried; Cook Meth N/S 4013550, 211, 5, 0.00%, Spinach-Cooked; Fresh or N/S; Baked15003240, 232, 6, 0.00%, Rice, brown-Cooked; Dried; Boiled11000091, 230, 5, 0.00%, Apple, dried-babyfood-Cooked; Dried; Cook Meth N/S 8002700, 214, 1, 0.00%, Pepper, bell-Cooked; Fresh or N/S; Fried/baked 8002720, 150, 6, 0.00%, Pepper, nonbell-Uncooked; Cured etc; Cook Meth N/S15003250, 230, 12, 0.00%, Rice, flour-Cooked; Dried; Cook Meth N/S11000070, 150, 1, 0.00%, Apple, fruit with peel-Uncooked; Cured etc; CookMeth N/S25002930, 213, 8, 0.00%, Pork, fat-Cooked; Fresh or N/S; Fried 8002720, 215, 1, 0.00%, Pepper, nonbell-Cooked; Fresh or N/S; Boiled/baked13021370, 130, 1, 0.00%, Currant, dried-Uncooked; Dried; Cook Meth N/S95002800, 130, 3, 0.00%, Pineapple, dried-Uncooked; Dried; Cook Meth N/S 8002700, 221, 3, 0.00%, Pepper, bell-Cooked; Frozen; Baked 9021350, 150, 5, 0.00%, Cucumber-Uncooked; Cured etc; Cook Meth N/S 8002730, 210, 8, 0.00%, Pepper, nonbell, dried-Cooked; Fresh or N/S; CookMeth N/S11000110, 240, 4, 0.00%, Apple, sauce-Cooked; Canned; Cook Meth N/S12000140, 120, 7, 0.00%, Apricot, juice-Uncooked; Frozen; Cook Meth N/S15003251, 240, 9, 0.00%, Rice, flour-babyfood-Cooked; Canned; Cook Meth N/S 1033000, 211, 9, 0.00%, Potato, tuber, w/o peel-Cooked; Fresh or N/S; Baked10002070, 120, 7, 0.00%, Lime, juice-Uncooked; Frozen; Cook Meth N/S11000110, 221, 1, 0.00%, Apple, sauce-Cooked; Frozen; Baked 8002720, 230, 3, 0.00%, Pepper, nonbell-Cooked; Dried; Cook Meth N/S12002860, 232, 3, 0.00%, Plum, prune, fresh-Cooked; Dried; Boiled 8002700, 150, 3, 0.00%, Pepper, bell-Uncooked; Cured etc; Cook Meth N/S25002930, 253, 7, 0.00%, Pork, fat-Cooked; Cured etc; Fried15001240, 240, 6, 0.00%, Corn, field, syrup-Cooked; Canned; Cook Meth N/S

263

95001780, 210, 3, 0.00%, Grape, raisin-Cooked; Fresh or N/S; Cook Meth N/S15001270, 242, 6, 0.00%, Corn, sweet-Cooked; Canned; Boiled95002350, 213, 1, 0.00%, Olive-Cooked; Fresh or N/S; Fried 5020700, 110, 1, 0.00%, Cabbage, Chinese, bok choy-Uncooked; Fresh or N/S;Cook Meth N/S25002930, 250, 4, 0.00%, Pork, fat-Cooked; Cured etc; Cook Meth N/S 4020850, 150, 1, 0.00%, Celery-Uncooked; Cured etc; Cook Meth N/S95002791, 240, 5, 0.00%, Pineapple-babyfood-Cooked; Canned; Cook Meth N/S10002001, 240, 4, 0.00%, Lemon, juice-babyfood-Cooked; Canned; Cook Meth N/S12000910, 240, 3, 0.00%, Cherry, juice-Cooked; Canned; Cook Meth N/S95002360, 900, 3, 0.00%, Olive, oil-Refined; FF N/A; Cook Meth N/S 8003770, 240, 4, 0.00%, Tomato, puree-Cooked; Canned; Cook Meth N/S 9023571, 240, 5, 0.00%, Squash, winter-babyfood-Cooked; Canned; Cook MethN/S 6010430, 240, 2, 0.00%, Bean, snap, succulent-Cooked; Canned; Cook Meth N/S95001780, 211, 3, 0.00%, Grape, raisin-Cooked; Fresh or N/S; Baked12002620, 240, 1, 0.00%, Peach, juice-Cooked; Canned; Cook Meth N/S10003700, 110, 1, 0.00%, Tangerine, juice-Uncooked; Fresh or N/S; Cook MethN/S 8002711, 240, 3, 0.00%, Pepper, bell, dried-babyfood-Cooked; Canned; CookMeth N/S 5020700, 150, 1, 0.00%, Cabbage, Chinese, bok choy-Uncooked; Cured etc;Cook Meth N/S95003600, 211, 2, 0.00%, Strawberry, juice-Cooked; Fresh or N/S; Baked 8001480, 212, 2, 0.00%, Eggplant-Cooked; Fresh or N/S; Boiled15001241, 230, 4, 0.00%, Corn, field, syrup-babyfood-Cooked; Dried; CookMeth N/S 8002700, 222, 1, 0.00%, Pepper, bell-Cooked; Frozen; Boiled95001780, 230, 3, 0.00%, Grape, raisin-Cooked; Dried; Cook Meth N/S 4013550, 110, 4, 0.00%, Spinach-Uncooked; Fresh or N/S; Cook Meth N/S 8003770, 212, 3, 0.00%, Tomato, puree-Cooked; Fresh or N/S; Boiled 8003770, 210, 3, 0.00%, Tomato, puree-Cooked; Fresh or N/S; Cook Meth N/S12002860, 211, 1, 0.00%, Plum, prune, fresh-Cooked; Fresh or N/S; Baked15001241, 240, 3, 0.00%, Corn, field, syrup-babyfood-Cooked; Canned; CookMeth N/S10003700, 120, 2, 0.00%, Tangerine, juice-Uncooked; Frozen; Cook Meth N/S 8002710, 212, 1, 0.00%, Pepper, bell, dried-Cooked; Fresh or N/S; Boiled 1033000, 210, 2, 0.00%, Potato, tuber, w/o peel-Cooked; Fresh or N/S; CookMeth N/S10002000, 212, 1, 0.00%, Lemon, juice-Cooked; Fresh or N/S; Boiled 1033660, 242, 1, 0.00%, Sweet potato-Cooked; Canned; Boiled11002680, 120, 2, 0.00%, Pear, juice-Uncooked; Frozen; Cook Meth N/S15001270, 212, 3, 0.00%, Corn, sweet-Cooked; Fresh or N/S; Boiled95002790, 210, 2, 0.00%, Pineapple-Cooked; Fresh or N/S; Cook Meth N/S 1032990, 211, 3, 0.00%, Potato, tuber, w/peel-Cooked; Fresh or N/S; Baked 4013550, 215, 1, 0.00%, Spinach-Cooked; Fresh or N/S; Boiled/baked15004020, 211, 3, 0.00%, Wheat, flour-Cooked; Fresh or N/S; Baked 8001480, 211, 1, 0.00%, Eggplant-Cooked; Fresh or N/S; Baked 8003790, 240, 2, 0.00%, Tomato, juice-Cooked; Canned; Cook Meth N/S 6010430, 221, 1, 0.00%, Bean, snap, succulent-Cooked; Frozen; Baked25002930, 211, 2, 0.00%, Pork, fat-Cooked; Fresh or N/S; Baked 4013551, 240, 2, 0.00%, Spinach-babyfood-Cooked; Canned; Cook Meth N/S11000080, 210, 1, 0.00%, Apple, peeled fruit-Cooked; Fresh or N/S; Cook MethN/S 4020850, 221, 1, 0.00%, Celery-Cooked; Frozen; Baked95001790, 210, 2, 0.00%, Grape, wine and sherry-Cooked; Fresh or N/S; CookMeth N/S12000910, 120, 1, 0.00%, Cherry, juice-Uncooked; Frozen; Cook Meth N/S10002411, 240, 1, 0.00%, Orange, juice-babyfood-Cooked; Canned; Cook MethN/S25002930, 230, 2, 0.00%, Pork, fat-Cooked; Dried; Cook Meth N/S 8003750, 240, 1, 0.00%, Tomato-Cooked; Canned; Cook Meth N/S15001240, 130, 2, 0.00%, Corn, field, syrup-Uncooked; Dried; Cook Meth N/S 8002340, 212, 1, 0.00%, Okra-Cooked; Fresh or N/S; Boiled95001750, 120, 1, 0.00%, Grape-Uncooked; Frozen; Cook Meth N/S

264

15001241, 130, 2, 0.00%, Corn, field, syrup-babyfood-Uncooked; Dried; CookMeth N/S25002931, 240, 1, 0.00%, Pork, fat-babyfood-Cooked; Canned; Cook Meth N/S95003600, 120, 1, 0.00%, Strawberry, juice-Uncooked; Frozen; Cook Meth N/S11000090, 210, 1, 0.00%, Apple, dried-Cooked; Fresh or N/S; Cook Meth N/S 1010780, 212, 2, 0.00%, Carrot-Cooked; Fresh or N/S; Boiled11000080, 213, 1, 0.00%, Apple, peeled fruit-Cooked; Fresh or N/S; Fried25002930, 240, 1, 0.00%, Pork, fat-Cooked; Canned; Cook Meth N/S 1010781, 240, 2, 0.00%, Carrot-babyfood-Cooked; Canned; Cook Meth N/S95003600, 213, 1, 0.00%, Strawberry, juice-Cooked; Fresh or N/S; Fried 6003490, 210, 1, 0.00%, Soybean, soy milk-Cooked; Fresh or N/S; Cook MethN/S 1032980, 213, 1, 0.00%, Potato, flour-Cooked; Fresh or N/S; Fried 1033660, 211, 1, 0.00%, Sweet potato-Cooked; Fresh or N/S; Baked25002901, 240, 1, 0.00%, Pork, meat-babyfood-Cooked; Canned; Cook Meth N/S11000110, 211, 1, 0.00%, Apple, sauce-Cooked; Fresh or N/S; Baked15003240, 211, 1, 0.00%, Rice, brown-Cooked; Fresh or N/S; Baked20003640, 211, 1, 0.00%, Sunflower, seed-Cooked; Fresh or N/S; Baked15003250, 210, 1, 0.00%, Rice, flour-Cooked; Fresh or N/S; Cook Meth N/S 6010430, 211, 1, 0.00%, Bean, snap, succulent-Cooked; Fresh or N/S; Baked 4011500, 110, 1, 0.00%, Endive-Uncooked; Fresh or N/S; Cook Meth N/S15003241, 230, 1, 0.00%, Rice, brown-babyfood-Cooked; Dried; Cook Meth N/S 1033660, 212, 1, 0.00%, Sweet potato-Cooked; Fresh or N/S; Boiled95001780, 213, 1, 0.00%, Grape, raisin-Cooked; Fresh or N/S; Fried 1010780, 242, 1, 0.00%, Carrot-Cooked; Canned; Boiled 8002730, 240, 1, 0.00%, Pepper, nonbell, dried-Cooked; Canned; Cook MethN/S 1010780, 222, 1, 0.00%, Carrot-Cooked; Frozen; Boiled15004020, 231, 1, 0.00%, Wheat, flour-Cooked; Dried; Baked11000080, 221, 1, 0.00%, Apple, peeled fruit-Cooked; Frozen; Baked15001270, 222, 1, 0.00%, Corn, sweet-Cooked; Frozen; Boiled15001241, 210, 1, 0.00%, Corn, field, syrup-babyfood-Cooked; Fresh or N/S;Cook Meth N/S 1033660, 215, 1, 0.00%, Sweet potato-Cooked; Fresh or N/S; Boiled/baked15003241, 240, 1, 0.00%, Rice, brown-babyfood-Cooked; Canned; Cook Meth N/S15003240, 210, 1, 0.00%, Rice, brown-Cooked; Fresh or N/S; Cook Meth N/S 8003790, 212, 1, 0.00%, Tomato, juice-Cooked; Fresh or N/S; Boiled15001231, 240, 1, 0.00%, Corn, field, starch-babyfood-Cooked; Canned; CookMeth N/S 8003790, 110, 1, 0.00%, Tomato, juice-Uncooked; Fresh or N/S; Cook Meth N/S95001320, 110, 1, 0.00%, Cranberry, juice-Uncooked; Fresh or N/S; Cook MethN/S95000230, 110, 1, 0.00%, Banana-Uncooked; Fresh or N/S; Cook Meth N/S

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Non-hispanic blacksLow percentile for CEC records: 95 Exposure (mg/day) = 0.005271High percentile for CEC records: 100 Exposure (mg/day) = 0.214837Number of actual records in this interval: 563

Critical foods/foodforms for this population (as derived from these records): N=number of appearances in all records (including duplicates) %=percent of total exposure for all records (including duplicates)

Food, FF, N , Percent, Food Name --------, ---, -----, -------, -------------11000070, 110, 164, 10.60%, Apple, fruit with peel-Uncooked; Fresh or N/S; CookMeth N/S 5021170, 212, 70, 10.36%, Collards-Cooked; Fresh or N/S; Boiled12000130, 130, 6, 5.04%, Apricot, dried-Uncooked; Dried; Cook Meth N/S95001750, 110, 76, 4.92%, Grape-Uncooked; Fresh or N/S; Cook Meth N/S13020570, 211, 54, 4.29%, Blueberry-Cooked; Fresh or N/S; Baked12002601, 240, 38, 3.86%, Peach-babyfood-Cooked; Canned; Cook Meth N/S95000190, 242, 1, 3.47%, Asparagus-Cooked; Canned; Boiled 5023890, 212, 32, 3.24%, Turnip, greens-Cooked; Fresh or N/S; Boiled12002600, 240, 78, 2.91%, Peach-Cooked; Canned; Cook Meth N/S11000110, 212, 48, 2.52%, Apple, sauce-Cooked; Fresh or N/S; Boiled95003600, 240, 99, 2.25%, Strawberry, juice-Cooked; Canned; Cook Meth N/S 6010430, 242, 61, 2.22%, Bean, snap, succulent-Cooked; Canned; Boiled13020571, 240, 8, 2.02%, Blueberry-babyfood-Cooked; Canned; Cook Meth N/S12002300, 110, 14, 1.98%, Nectarine-Uncooked; Fresh or N/S; Cook Meth N/S95003590, 110, 30, 1.92%, Strawberry-Uncooked; Fresh or N/S; Cook Meth N/S 9010750, 110, 31, 1.62%, Cantaloupe-Uncooked; Fresh or N/S; Cook Meth N/S 5023890, 242, 7, 1.28%, Turnip, greens-Cooked; Canned; Boiled 4020850, 110, 59, 1.25%, Celery-Uncooked; Fresh or N/S; Cook Meth N/S12002600, 110, 20, 1.20%, Peach-Uncooked; Fresh or N/S; Cook Meth N/S95000190, 212, 6, 1.19%, Asparagus-Cooked; Fresh or N/S; Boiled11002660, 240, 49, 1.14%, Pear-Cooked; Canned; Cook Meth N/S11000100, 110, 103, 1.14%, Apple, juice-Uncooked; Fresh or N/S; Cook Meth N/S11000111, 240, 30, 1.09%, Apple, sauce-babyfood-Cooked; Canned; Cook Meth N/S 6010431, 240, 18, 1.06%, Bean, snap, succulent-babyfood-Cooked; Canned; CookMeth N/S 5021170, 242, 7, 1.03%, Collards-Cooked; Canned; Boiled11002660, 110, 15, 0.96%, Pear-Uncooked; Fresh or N/S; Cook Meth N/S 5022290, 212, 12, 0.90%, Mustard greens-Cooked; Fresh or N/S; Boiled 4020850, 212, 29, 0.90%, Celery-Cooked; Fresh or N/S; Boiled11002661, 240, 16, 0.90%, Pear-babyfood-Cooked; Canned; Cook Meth N/S95001760, 240, 98, 0.86%, Grape, juice-Cooked; Canned; Cook Meth N/S95001760, 110, 40, 0.81%, Grape, juice-Uncooked; Fresh or N/S; Cook Meth N/S 6010430, 212, 24, 0.79%, Bean, snap, succulent-Cooked; Fresh or N/S; Boiled95002350, 240, 14, 0.77%, Olive-Cooked; Canned; Cook Meth N/S13013200, 240, 21, 0.76%, Raspberry-Cooked; Canned; Cook Meth N/S 4020850, 210, 47, 0.72%, Celery-Cooked; Fresh or N/S; Cook Meth N/S10002400, 110, 46, 0.70%, Orange-Uncooked; Fresh or N/S; Cook Meth N/S 5022290, 242, 4, 0.59%, Mustard greens-Cooked; Canned; Boiled13020570, 214, 5, 0.57%, Blueberry-Cooked; Fresh or N/S; Fried/baked11000081, 240, 18, 0.52%, Apple, peeled fruit-babyfood-Cooked; Canned; CookMeth N/S95003590, 240, 21, 0.52%, Strawberry-Cooked; Canned; Cook Meth N/S12000121, 240, 8, 0.48%, Apricot-babyfood-Cooked; Canned; Cook Meth N/S10002410, 110, 104, 0.44%, Orange, juice-Uncooked; Fresh or N/S; Cook Meth N/S12000141, 240, 9, 0.43%, Apricot, juice-babyfood-Cooked; Canned; Cook MethN/S12002880, 110, 1, 0.42%, Plum, prune, juice-Uncooked; Fresh or N/S; CookMeth N/S12002850, 110, 10, 0.42%, Plum-Uncooked; Fresh or N/S; Cook Meth N/S 9011870, 110, 8, 0.39%, Honeydew melon-Uncooked; Fresh or N/S; Cook MethN/S 6010430, 222, 12, 0.38%, Bean, snap, succulent-Cooked; Frozen; Boiled

266

8002700, 210, 16, 0.38%, Pepper, bell-Cooked; Fresh or N/S; Cook Meth N/S13010550, 240, 25, 0.36%, Blackberry-Cooked; Canned; Cook Meth N/S11000101, 240, 30, 0.32%, Apple, juice-babyfood-Cooked; Canned; Cook Meth N/S13020570, 120, 9, 0.32%, Blueberry-Uncooked; Frozen; Cook Meth N/S 5021170, 222, 3, 0.31%, Collards-Cooked; Frozen; Boiled11002681, 240, 6, 0.31%, Pear, juice-babyfood-Cooked; Canned; Cook Meth N/S12000120, 240, 22, 0.27%, Apricot-Cooked; Canned; Cook Meth N/S95001750, 240, 48, 0.27%, Grape-Cooked; Canned; Cook Meth N/S 4020851, 240, 6, 0.26%, Celery-babyfood-Cooked; Canned; Cook Meth N/S95003590, 120, 6, 0.25%, Strawberry-Uncooked; Frozen; Cook Meth N/S11000100, 240, 47, 0.24%, Apple, juice-Cooked; Canned; Cook Meth N/S13020570, 110, 12, 0.22%, Blueberry-Uncooked; Fresh or N/S; Cook Meth N/S13020570, 240, 28, 0.21%, Blueberry-Cooked; Canned; Cook Meth N/S 4020850, 232, 6, 0.21%, Celery-Cooked; Dried; Boiled95002350, 211, 5, 0.21%, Olive-Cooked; Fresh or N/S; Baked12000910, 110, 2, 0.20%, Cherry, juice-Uncooked; Fresh or N/S; Cook Meth N/S95003600, 210, 19, 0.20%, Strawberry, juice-Cooked; Fresh or N/S; Cook MethN/S12002620, 110, 3, 0.19%, Peach, juice-Uncooked; Fresh or N/S; Cook Meth N/S 5023890, 222, 1, 0.19%, Turnip, greens-Cooked; Frozen; Boiled12000910, 210, 19, 0.18%, Cherry, juice-Cooked; Fresh or N/S; Cook Meth N/S95001761, 240, 5, 0.17%, Grape, juice-babyfood-Cooked; Canned; Cook Meth N/S95001750, 210, 19, 0.17%, Grape-Cooked; Fresh or N/S; Cook Meth N/S 8002700, 110, 22, 0.16%, Pepper, bell-Uncooked; Fresh or N/S; Cook Meth N/S 9021350, 110, 19, 0.16%, Cucumber-Uncooked; Fresh or N/S; Cook Meth N/S11002660, 210, 19, 0.16%, Pear-Cooked; Fresh or N/S; Cook Meth N/S12002861, 240, 2, 0.15%, Plum, prune, fresh-babyfood-Cooked; Canned; CookMeth N/S10002000, 110, 22, 0.14%, Lemon, juice-Uncooked; Fresh or N/S; Cook Meth N/S 8002340, 210, 4, 0.14%, Okra-Cooked; Fresh or N/S; Cook Meth N/S13013201, 240, 8, 0.14%, Raspberry-babyfood-Cooked; Canned; Cook Meth N/S12002881, 240, 3, 0.14%, Plum, prune, juice-babyfood-Cooked; Canned; CookMeth N/S95002810, 110, 8, 0.13%, Pineapple, juice-Uncooked; Fresh or N/S; Cook MethN/S10001810, 240, 7, 0.12%, Grapefruit, juice-Cooked; Canned; Cook Meth N/S 5022290, 222, 1, 0.12%, Mustard greens-Cooked; Frozen; Boiled12000900, 240, 31, 0.11%, Cherry-Cooked; Canned; Cook Meth N/S12002600, 120, 3, 0.11%, Peach-Uncooked; Frozen; Cook Meth N/S95002810, 240, 34, 0.11%, Pineapple, juice-Cooked; Canned; Cook Meth N/S13020570, 213, 1, 0.10%, Blueberry-Cooked; Fresh or N/S; Fried95003600, 110, 1, 0.10%, Strawberry, juice-Uncooked; Fresh or N/S; Cook MethN/S 8002340, 220, 1, 0.10%, Okra-Cooked; Frozen; Cook Meth N/S 1033000, 212, 31, 0.09%, Potato, tuber, w/o peel-Cooked; Fresh or N/S;Boiled12000901, 240, 4, 0.09%, Cherry-babyfood-Cooked; Canned; Cook Meth N/S12002600, 211, 6, 0.09%, Peach-Cooked; Fresh or N/S; Baked 5021940, 212, 12, 0.08%, Kale-Cooked; Fresh or N/S; Boiled 4020850, 215, 6, 0.07%, Celery-Cooked; Fresh or N/S; Boiled/baked95002790, 240, 10, 0.07%, Pineapple-Cooked; Canned; Cook Meth N/S12000900, 211, 3, 0.07%, Cherry-Cooked; Fresh or N/S; Baked95001780, 130, 17, 0.06%, Grape, raisin-Uncooked; Dried; Cook Meth N/S12000900, 110, 5, 0.06%, Cherry-Uncooked; Fresh or N/S; Cook Meth N/S12000140, 240, 4, 0.06%, Apricot, juice-Cooked; Canned; Cook Meth N/S13013200, 110, 11, 0.06%, Raspberry-Uncooked; Fresh or N/S; Cook Meth N/S 4013550, 222, 4, 0.06%, Spinach-Cooked; Frozen; Boiled11002680, 240, 7, 0.06%, Pear, juice-Cooked; Canned; Cook Meth N/S 8002700, 213, 5, 0.06%, Pepper, bell-Cooked; Fresh or N/S; Fried10002410, 120, 19, 0.05%, Orange, juice-Uncooked; Frozen; Cook Meth N/S11000080, 240, 2, 0.05%, Apple, peeled fruit-Cooked; Canned; Cook Meth N/S11000080, 211, 4, 0.05%, Apple, peeled fruit-Cooked; Fresh or N/S; Baked10003700, 240, 8, 0.05%, Tangerine, juice-Cooked; Canned; Cook Meth N/S13013210, 110, 2, 0.05%, Raspberry, juice-Uncooked; Fresh or N/S; Cook MethN/S

267

4020850, 211, 2, 0.05%, Celery-Cooked; Fresh or N/S; Baked11000100, 120, 2, 0.05%, Apple, juice-Uncooked; Frozen; Cook Meth N/S 9021350, 240, 19, 0.04%, Cucumber-Cooked; Canned; Cook Meth N/S 4013550, 212, 6, 0.04%, Spinach-Cooked; Fresh or N/S; Boiled12000911, 240, 3, 0.04%, Cherry, juice-babyfood-Cooked; Canned; Cook MethN/S10002000, 240, 7, 0.04%, Lemon, juice-Cooked; Canned; Cook Meth N/S12002621, 240, 1, 0.04%, Peach, juice-babyfood-Cooked; Canned; Cook Meth N/S 6010430, 213, 2, 0.04%, Bean, snap, succulent-Cooked; Fresh or N/S; Fried12000130, 211, 1, 0.03%, Apricot, dried-Cooked; Fresh or N/S; Baked10002070, 240, 5, 0.03%, Lime, juice-Cooked; Canned; Cook Meth N/S11000070, 211, 2, 0.03%, Apple, fruit with peel-Cooked; Fresh or N/S; Baked 8002700, 211, 4, 0.03%, Pepper, bell-Cooked; Fresh or N/S; Baked15003251, 230, 14, 0.03%, Rice, flour-babyfood-Cooked; Dried; Cook Meth N/S10002000, 210, 12, 0.03%, Lemon, juice-Cooked; Fresh or N/S; Cook Meth N/S95003590, 211, 5, 0.03%, Strawberry-Cooked; Fresh or N/S; Baked12002620, 240, 1, 0.03%, Peach, juice-Cooked; Canned; Cook Meth N/S 5020700, 210, 1, 0.02%, Cabbage, Chinese, bok choy-Cooked; Fresh or N/S;Cook Meth N/S13013200, 211, 4, 0.02%, Raspberry-Cooked; Fresh or N/S; Baked12002851, 240, 4, 0.02%, Plum-babyfood-Cooked; Canned; Cook Meth N/S 8002700, 212, 3, 0.02%, Pepper, bell-Cooked; Fresh or N/S; Boiled 9013990, 110, 7, 0.02%, Watermelon-Uncooked; Fresh or N/S; Cook Meth N/S15003240, 210, 3, 0.02%, Rice, brown-Cooked; Fresh or N/S; Cook Meth N/S10002410, 240, 7, 0.02%, Orange, juice-Cooked; Canned; Cook Meth N/S 8002720, 110, 1, 0.02%, Pepper, nonbell-Uncooked; Fresh or N/S; Cook MethN/S11000090, 211, 3, 0.02%, Apple, dried-Cooked; Fresh or N/S; Baked13013200, 120, 3, 0.02%, Raspberry-Uncooked; Frozen; Cook Meth N/S95002811, 240, 3, 0.02%, Pineapple, juice-babyfood-Cooked; Canned; Cook MethN/S 1032990, 212, 7, 0.01%, Potato, tuber, w/peel-Cooked; Fresh or N/S; Boiled 8002700, 215, 3, 0.01%, Pepper, bell-Cooked; Fresh or N/S; Boiled/baked95002790, 110, 3, 0.01%, Pineapple-Uncooked; Fresh or N/S; Cook Meth N/S13013210, 240, 5, 0.01%, Raspberry, juice-Cooked; Canned; Cook Meth N/S13010580, 240, 5, 0.01%, Boysenberry-Cooked; Canned; Cook Meth N/S10002000, 130, 4, 0.01%, Lemon, juice-Uncooked; Dried; Cook Meth N/S 1033661, 240, 4, 0.01%, Sweet potato-babyfood-Cooked; Canned; Cook Meth N/S25002930, 250, 5, 0.01%, Pork, fat-Cooked; Cured etc; Cook Meth N/S 4020850, 242, 1, 0.01%, Celery-Cooked; Canned; Boiled 8002700, 222, 2, 0.01%, Pepper, bell-Cooked; Frozen; Boiled 5021940, 242, 1, 0.01%, Kale-Cooked; Canned; Boiled25002930, 210, 7, 0.01%, Pork, fat-Cooked; Fresh or N/S; Cook Meth N/S 8003770, 240, 8, 0.01%, Tomato, puree-Cooked; Canned; Cook Meth N/S11000080, 213, 2, 0.01%, Apple, peeled fruit-Cooked; Fresh or N/S; Fried10002411, 240, 2, 0.01%, Orange, juice-babyfood-Cooked; Canned; Cook MethN/S95001780, 230, 5, 0.01%, Grape, raisin-Cooked; Dried; Cook Meth N/S10001800, 110, 3, 0.01%, Grapefruit-Uncooked; Fresh or N/S; Cook Meth N/S15001270, 242, 4, 0.01%, Corn, sweet-Cooked; Canned; Boiled12002860, 232, 1, 0.01%, Plum, prune, fresh-Cooked; Dried; Boiled 4020850, 213, 1, 0.01%, Celery-Cooked; Fresh or N/S; Fried11000090, 230, 4, 0.01%, Apple, dried-Cooked; Dried; Cook Meth N/S12002610, 130, 1, 0.01%, Peach, dried-Uncooked; Dried; Cook Meth N/S15003251, 240, 3, 0.01%, Rice, flour-babyfood-Cooked; Canned; Cook Meth N/S15001240, 240, 5, 0.01%, Corn, field, syrup-Cooked; Canned; Cook Meth N/S10002000, 211, 3, 0.01%, Lemon, juice-Cooked; Fresh or N/S; Baked 8002730, 210, 4, 0.01%, Pepper, nonbell, dried-Cooked; Fresh or N/S; CookMeth N/S 8002720, 210, 1, 0.01%, Pepper, nonbell-Cooked; Fresh or N/S; Cook Meth N/S95001760, 210, 3, 0.01%, Grape, juice-Cooked; Fresh or N/S; Cook Meth N/S10002001, 240, 3, 0.01%, Lemon, juice-babyfood-Cooked; Canned; Cook Meth N/S15001241, 240, 3, 0.01%, Corn, field, syrup-babyfood-Cooked; Canned; CookMeth N/S

268

10001070, 110, 1, 0.01%, Citrus hybrids-Uncooked; Fresh or N/S; Cook MethN/S 1010781, 240, 3, 0.00%, Carrot-babyfood-Cooked; Canned; Cook Meth N/S10002070, 120, 2, 0.00%, Lime, juice-Uncooked; Frozen; Cook Meth N/S 1033000, 211, 1, 0.00%, Potato, tuber, w/o peel-Cooked; Fresh or N/S; Baked15003250, 230, 3, 0.00%, Rice, flour-Cooked; Dried; Cook Meth N/S11000091, 230, 1, 0.00%, Apple, dried-babyfood-Cooked; Dried; Cook Meth N/S 8002720, 240, 1, 0.00%, Pepper, nonbell-Cooked; Canned; Cook Meth N/S25002930, 213, 2, 0.00%, Pork, fat-Cooked; Fresh or N/S; Fried 1032981, 240, 1, 0.00%, Potato, flour-babyfood-Cooked; Canned; Cook MethN/S25002930, 253, 3, 0.00%, Pork, fat-Cooked; Cured etc; Fried 1033660, 210, 2, 0.00%, Sweet potato-Cooked; Fresh or N/S; Cook Meth N/S13010580, 120, 2, 0.00%, Boysenberry-Uncooked; Frozen; Cook Meth N/S13010550, 120, 2, 0.00%, Blackberry-Uncooked; Frozen; Cook Meth N/S13013210, 120, 2, 0.00%, Raspberry, juice-Uncooked; Frozen; Cook Meth N/S13010580, 110, 1, 0.00%, Boysenberry-Uncooked; Fresh or N/S; Cook Meth N/S13010550, 110, 1, 0.00%, Blackberry-Uncooked; Fresh or N/S; Cook Meth N/S25002931, 240, 1, 0.00%, Pork, fat-babyfood-Cooked; Canned; Cook Meth N/S10003690, 110, 1, 0.00%, Tangerine-Uncooked; Fresh or N/S; Cook Meth N/S 8002730, 212, 2, 0.00%, Pepper, nonbell, dried-Cooked; Fresh or N/S; Boiled 4020850, 240, 1, 0.00%, Celery-Cooked; Canned; Cook Meth N/S10001810, 110, 1, 0.00%, Grapefruit, juice-Uncooked; Fresh or N/S; Cook MethN/S12000140, 110, 1, 0.00%, Apricot, juice-Uncooked; Fresh or N/S; Cook MethN/S12000900, 120, 1, 0.00%, Cherry-Uncooked; Frozen; Cook Meth N/S11000090, 130, 1, 0.00%, Apple, dried-Uncooked; Dried; Cook Meth N/S11002670, 130, 1, 0.00%, Pear, dried-Uncooked; Dried; Cook Meth N/S 1033660, 211, 1, 0.00%, Sweet potato-Cooked; Fresh or N/S; Baked 8003770, 212, 1, 0.00%, Tomato, puree-Cooked; Fresh or N/S; Boiled 6003490, 230, 1, 0.00%, Soybean, soy milk-Cooked; Dried; Cook Meth N/S 8003770, 210, 1, 0.00%, Tomato, puree-Cooked; Fresh or N/S; Cook Meth N/S15003250, 232, 1, 0.00%, Rice, flour-Cooked; Dried; Boiled 8002700, 221, 1, 0.00%, Pepper, bell-Cooked; Frozen; Baked15001270, 222, 1, 0.00%, Corn, sweet-Cooked; Frozen; Boiled 8002730, 240, 1, 0.00%, Pepper, nonbell, dried-Cooked; Canned; Cook MethN/S 8002700, 240, 1, 0.00%, Pepper, bell-Cooked; Canned; Cook Meth N/S12000910, 240, 1, 0.00%, Cherry, juice-Cooked; Canned; Cook Meth N/S 8003750, 212, 1, 0.00%, Tomato-Cooked; Fresh or N/S; Boiled 6003490, 210, 1, 0.00%, Soybean, soy milk-Cooked; Fresh or N/S; Cook MethN/S12000140, 120, 1, 0.00%, Apricot, juice-Uncooked; Frozen; Cook Meth N/S

269

Non-hisp/non-white/non-blackLow percentile for CEC records: 95 Exposure (mg/day) = 0.007139High percentile for CEC records: 100 Exposure (mg/day) = 0.042695Number of actual records in this interval: 181

Critical foods/foodforms for this population (as derived from these records): N=number of appearances in all records (including duplicates) %=percent of total exposure for all records (including duplicates)

Food, FF, N , Percent, Food Name --------, ---, -----, -------, -------------11000070, 110, 54, 8.94%, Apple, fruit with peel-Uncooked; Fresh or N/S; CookMeth N/S95001750, 110, 28, 7.61%, Grape-Uncooked; Fresh or N/S; Cook Meth N/S 4020850, 110, 22, 4.73%, Celery-Uncooked; Fresh or N/S; Cook Meth N/S95003590, 110, 22, 4.30%, Strawberry-Uncooked; Fresh or N/S; Cook Meth N/S12002300, 110, 10, 3.84%, Nectarine-Uncooked; Fresh or N/S; Cook Meth N/S13020570, 110, 23, 3.76%, Blueberry-Uncooked; Fresh or N/S; Cook Meth N/S95000190, 212, 5, 3.32%, Asparagus-Cooked; Fresh or N/S; Boiled12002601, 240, 11, 3.27%, Peach-babyfood-Cooked; Canned; Cook Meth N/S 5021170, 212, 5, 2.61%, Collards-Cooked; Fresh or N/S; Boiled11002660, 110, 10, 2.54%, Pear-Uncooked; Fresh or N/S; Cook Meth N/S12002600, 240, 27, 2.51%, Peach-Cooked; Canned; Cook Meth N/S13013200, 240, 22, 2.40%, Raspberry-Cooked; Canned; Cook Meth N/S13020571, 240, 3, 2.31%, Blueberry-babyfood-Cooked; Canned; Cook Meth N/S95000190, 242, 2, 2.16%, Asparagus-Cooked; Canned; Boiled95002350, 240, 9, 2.13%, Olive-Cooked; Canned; Cook Meth N/S13020570, 214, 7, 2.00%, Blueberry-Cooked; Fresh or N/S; Fried/baked 9010750, 110, 11, 1.94%, Cantaloupe-Uncooked; Fresh or N/S; Cook Meth N/S13020570, 211, 11, 1.83%, Blueberry-Cooked; Fresh or N/S; Baked12000120, 240, 22, 1.73%, Apricot-Cooked; Canned; Cook Meth N/S95003590, 240, 22, 1.64%, Strawberry-Cooked; Canned; Cook Meth N/S11002660, 240, 12, 1.64%, Pear-Cooked; Canned; Cook Meth N/S 4020850, 210, 12, 1.49%, Celery-Cooked; Fresh or N/S; Cook Meth N/S12002600, 110, 12, 1.49%, Peach-Uncooked; Fresh or N/S; Cook Meth N/S 9011870, 110, 7, 1.47%, Honeydew melon-Uncooked; Fresh or N/S; Cook MethN/S 4020850, 242, 7, 1.44%, Celery-Cooked; Canned; Boiled11000111, 240, 12, 1.33%, Apple, sauce-babyfood-Cooked; Canned; Cook Meth N/S11000110, 212, 9, 1.19%, Apple, sauce-Cooked; Fresh or N/S; Boiled 6010430, 242, 11, 1.14%, Bean, snap, succulent-Cooked; Canned; Boiled11000100, 110, 37, 1.07%, Apple, juice-Uncooked; Fresh or N/S; Cook Meth N/S13010550, 240, 20, 1.06%, Blackberry-Cooked; Canned; Cook Meth N/S 4020850, 212, 22, 0.97%, Celery-Cooked; Fresh or N/S; Boiled12000121, 240, 4, 0.91%, Apricot-babyfood-Cooked; Canned; Cook Meth N/S95003600, 110, 1, 0.76%, Strawberry, juice-Uncooked; Fresh or N/S; Cook MethN/S12000141, 240, 3, 0.74%, Apricot, juice-babyfood-Cooked; Canned; Cook MethN/S 6010430, 212, 15, 0.71%, Bean, snap, succulent-Cooked; Fresh or N/S; Boiled10002400, 110, 22, 0.68%, Orange-Uncooked; Fresh or N/S; Cook Meth N/S13010560, 120, 1, 0.67%, Blackberry, juice-Uncooked; Frozen; Cook Meth N/S95001760, 110, 11, 0.66%, Grape, juice-Uncooked; Fresh or N/S; Cook Meth N/S10002410, 110, 48, 0.65%, Orange, juice-Uncooked; Fresh or N/S; Cook Meth N/S11002661, 240, 3, 0.63%, Pear-babyfood-Cooked; Canned; Cook Meth N/S13020570, 213, 2, 0.59%, Blueberry-Cooked; Fresh or N/S; Fried95002350, 211, 5, 0.54%, Olive-Cooked; Fresh or N/S; Baked 5022290, 212, 3, 0.53%, Mustard greens-Cooked; Fresh or N/S; Boiled12002850, 110, 4, 0.46%, Plum-Uncooked; Fresh or N/S; Cook Meth N/S12000120, 110, 2, 0.46%, Apricot-Uncooked; Fresh or N/S; Cook Meth N/S13010561, 240, 2, 0.44%, Blackberry, juice-babyfood-Cooked; Canned; CookMeth N/S11000081, 240, 7, 0.41%, Apple, peeled fruit-babyfood-Cooked; Canned; CookMeth N/S

270

13013200, 110, 19, 0.38%, Raspberry-Uncooked; Fresh or N/S; Cook Meth N/S 9021350, 110, 12, 0.37%, Cucumber-Uncooked; Fresh or N/S; Cook Meth N/S95003600, 240, 7, 0.36%, Strawberry, juice-Cooked; Canned; Cook Meth N/S 8002700, 110, 9, 0.33%, Pepper, bell-Uncooked; Fresh or N/S; Cook Meth N/S 5021170, 242, 1, 0.31%, Collards-Cooked; Canned; Boiled 4020851, 240, 3, 0.30%, Celery-babyfood-Cooked; Canned; Cook Meth N/S95001750, 240, 16, 0.28%, Grape-Cooked; Canned; Cook Meth N/S12002620, 110, 1, 0.28%, Peach, juice-Uncooked; Fresh or N/S; Cook Meth N/S 8002700, 210, 9, 0.27%, Pepper, bell-Cooked; Fresh or N/S; Cook Meth N/S 6010431, 240, 2, 0.25%, Bean, snap, succulent-babyfood-Cooked; Canned; CookMeth N/S95001760, 240, 12, 0.24%, Grape, juice-Cooked; Canned; Cook Meth N/S 5023890, 242, 1, 0.23%, Turnip, greens-Cooked; Canned; Boiled 5021940, 212, 4, 0.21%, Kale-Cooked; Fresh or N/S; Boiled11000101, 240, 9, 0.18%, Apple, juice-babyfood-Cooked; Canned; Cook Meth N/S95003600, 210, 6, 0.17%, Strawberry, juice-Cooked; Fresh or N/S; Cook MethN/S13013201, 240, 3, 0.16%, Raspberry-babyfood-Cooked; Canned; Cook Meth N/S 8002700, 240, 1, 0.15%, Pepper, bell-Cooked; Canned; Cook Meth N/S 4020850, 211, 2, 0.15%, Celery-Cooked; Fresh or N/S; Baked 5023890, 212, 1, 0.14%, Turnip, greens-Cooked; Fresh or N/S; Boiled11002681, 240, 3, 0.14%, Pear, juice-babyfood-Cooked; Canned; Cook Meth N/S95003600, 120, 1, 0.14%, Strawberry, juice-Uncooked; Frozen; Cook Meth N/S95002810, 110, 2, 0.13%, Pineapple, juice-Uncooked; Fresh or N/S; Cook MethN/S 5020700, 210, 5, 0.13%, Cabbage, Chinese, bok choy-Cooked; Fresh or N/S;Cook Meth N/S 9021350, 240, 4, 0.13%, Cucumber-Cooked; Canned; Cook Meth N/S 8002700, 211, 7, 0.13%, Pepper, bell-Cooked; Fresh or N/S; Baked12000910, 210, 5, 0.12%, Cherry, juice-Cooked; Fresh or N/S; Cook Meth N/S95001750, 210, 5, 0.11%, Grape-Cooked; Fresh or N/S; Cook Meth N/S 4013550, 212, 8, 0.11%, Spinach-Cooked; Fresh or N/S; Boiled 4020850, 215, 2, 0.11%, Celery-Cooked; Fresh or N/S; Boiled/baked11002660, 210, 5, 0.11%, Pear-Cooked; Fresh or N/S; Cook Meth N/S 6010430, 222, 3, 0.10%, Bean, snap, succulent-Cooked; Frozen; Boiled 1033000, 212, 11, 0.10%, Potato, tuber, w/o peel-Cooked; Fresh or N/S;Boiled13020570, 240, 5, 0.09%, Blueberry-Cooked; Canned; Cook Meth N/S13013211, 240, 2, 0.09%, Raspberry, juice-babyfood-Cooked; Canned; Cook MethN/S12000130, 211, 1, 0.09%, Apricot, dried-Cooked; Fresh or N/S; Baked11000110, 210, 1, 0.08%, Apple, sauce-Cooked; Fresh or N/S; Cook Meth N/S13013200, 211, 5, 0.08%, Raspberry-Cooked; Fresh or N/S; Baked10002410, 120, 6, 0.08%, Orange, juice-Uncooked; Frozen; Cook Meth N/S95001761, 240, 4, 0.07%, Grape, juice-babyfood-Cooked; Canned; Cook Meth N/S11000100, 240, 7, 0.07%, Apple, juice-Cooked; Canned; Cook Meth N/S12000900, 240, 5, 0.07%, Cherry-Cooked; Canned; Cook Meth N/S11000100, 120, 2, 0.06%, Apple, juice-Uncooked; Frozen; Cook Meth N/S95003590, 211, 6, 0.06%, Strawberry-Cooked; Fresh or N/S; Baked95001780, 130, 3, 0.06%, Grape, raisin-Uncooked; Dried; Cook Meth N/S12002600, 211, 1, 0.05%, Peach-Cooked; Fresh or N/S; Baked12000911, 240, 1, 0.05%, Cherry, juice-babyfood-Cooked; Canned; Cook MethN/S 6010430, 213, 2, 0.04%, Bean, snap, succulent-Cooked; Fresh or N/S; Fried 8002700, 213, 3, 0.04%, Pepper, bell-Cooked; Fresh or N/S; Fried95001790, 110, 2, 0.04%, Grape, wine and sherry-Uncooked; Fresh or N/S; CookMeth N/S95003601, 240, 2, 0.04%, Strawberry, juice-babyfood-Cooked; Canned; CookMeth N/S11000091, 230, 1, 0.04%, Apple, dried-babyfood-Cooked; Dried; Cook Meth N/S12000900, 110, 4, 0.03%, Cherry-Uncooked; Fresh or N/S; Cook Meth N/S 8002700, 212, 1, 0.03%, Pepper, bell-Cooked; Fresh or N/S; Boiled 5021940, 242, 1, 0.03%, Kale-Cooked; Canned; Boiled13020570, 120, 2, 0.03%, Blueberry-Uncooked; Frozen; Cook Meth N/S10002000, 110, 2, 0.03%, Lemon, juice-Uncooked; Fresh or N/S; Cook Meth N/S

271

12002600, 210, 1, 0.03%, Peach-Cooked; Fresh or N/S; Cook Meth N/S95000190, 213, 1, 0.02%, Asparagus-Cooked; Fresh or N/S; Fried10003700, 240, 3, 0.02%, Tangerine, juice-Cooked; Canned; Cook Meth N/S 8002700, 215, 1, 0.02%, Pepper, bell-Cooked; Fresh or N/S; Boiled/baked 4020850, 213, 2, 0.02%, Celery-Cooked; Fresh or N/S; Fried95002810, 240, 4, 0.02%, Pineapple, juice-Cooked; Canned; Cook Meth N/S 9013990, 110, 2, 0.02%, Watermelon-Uncooked; Fresh or N/S; Cook Meth N/S95002790, 240, 2, 0.02%, Pineapple-Cooked; Canned; Cook Meth N/S95003600, 211, 1, 0.02%, Strawberry, juice-Cooked; Fresh or N/S; Baked12002851, 240, 1, 0.02%, Plum-babyfood-Cooked; Canned; Cook Meth N/S 8002340, 150, 1, 0.02%, Okra-Uncooked; Cured etc; Cook Meth N/S 8002720, 110, 1, 0.02%, Pepper, nonbell-Uncooked; Fresh or N/S; Cook MethN/S15003240, 232, 1, 0.02%, Rice, brown-Cooked; Dried; Boiled11000090, 211, 2, 0.02%, Apple, dried-Cooked; Fresh or N/S; Baked25002930, 250, 1, 0.02%, Pork, fat-Cooked; Cured etc; Cook Meth N/S11002680, 240, 2, 0.01%, Pear, juice-Cooked; Canned; Cook Meth N/S10002000, 240, 2, 0.01%, Lemon, juice-Cooked; Canned; Cook Meth N/S 5020700, 150, 1, 0.01%, Cabbage, Chinese, bok choy-Uncooked; Cured etc;Cook Meth N/S95001780, 232, 1, 0.01%, Grape, raisin-Cooked; Dried; Boiled13013210, 240, 1, 0.01%, Raspberry, juice-Cooked; Canned; Cook Meth N/S13010580, 240, 1, 0.01%, Boysenberry-Cooked; Canned; Cook Meth N/S12002870, 130, 1, 0.01%, Plum, prune, dried-Uncooked; Dried; Cook Meth N/S10002000, 210, 2, 0.01%, Lemon, juice-Cooked; Fresh or N/S; Cook Meth N/S95001760, 120, 1, 0.01%, Grape, juice-Uncooked; Frozen; Cook Meth N/S 8001480, 214, 2, 0.01%, Eggplant-Cooked; Fresh or N/S; Fried/baked12000901, 240, 1, 0.01%, Cherry-babyfood-Cooked; Canned; Cook Meth N/S12000140, 240, 1, 0.01%, Apricot, juice-Cooked; Canned; Cook Meth N/S 1032990, 212, 1, 0.01%, Potato, tuber, w/peel-Cooked; Fresh or N/S; Boiled12002861, 240, 1, 0.01%, Plum, prune, fresh-babyfood-Cooked; Canned; CookMeth N/S 1033000, 211, 1, 0.01%, Potato, tuber, w/o peel-Cooked; Fresh or N/S; Baked10002000, 211, 1, 0.01%, Lemon, juice-Cooked; Fresh or N/S; Baked25002930, 242, 2, 0.01%, Pork, fat-Cooked; Canned; Boiled 8002730, 212, 1, 0.01%, Pepper, nonbell, dried-Cooked; Fresh or N/S; Boiled 6010430, 221, 1, 0.01%, Bean, snap, succulent-Cooked; Frozen; Baked11000080, 221, 1, 0.01%, Apple, peeled fruit-Cooked; Frozen; Baked25002930, 210, 1, 0.01%, Pork, fat-Cooked; Fresh or N/S; Cook Meth N/S15003240, 210, 1, 0.01%, Rice, brown-Cooked; Fresh or N/S; Cook Meth N/S25002930, 213, 1, 0.01%, Pork, fat-Cooked; Fresh or N/S; Fried15001270, 242, 1, 0.01%, Corn, sweet-Cooked; Canned; Boiled13013210, 120, 1, 0.01%, Raspberry, juice-Uncooked; Frozen; Cook Meth N/S13010580, 120, 1, 0.01%, Boysenberry-Uncooked; Frozen; Cook Meth N/S13010550, 120, 1, 0.01%, Blackberry-Uncooked; Frozen; Cook Meth N/S10002410, 240, 1, 0.01%, Orange, juice-Cooked; Canned; Cook Meth N/S95002790, 211, 1, 0.00%, Pineapple-Cooked; Fresh or N/S; Baked 1033660, 212, 1, 0.00%, Sweet potato-Cooked; Fresh or N/S; Boiled12000140, 120, 1, 0.00%, Apricot, juice-Uncooked; Frozen; Cook Meth N/S25002930, 221, 1, 0.00%, Pork, fat-Cooked; Frozen; Baked21000440, 211, 1, 0.00%, Beef, meat-Cooked; Fresh or N/S; Baked15001240, 240, 1, 0.00%, Corn, field, syrup-Cooked; Canned; Cook Meth N/S 8002730, 210, 1, 0.00%, Pepper, nonbell, dried-Cooked; Fresh or N/S; CookMeth N/S 9021350, 212, 1, 0.00%, Cucumber-Cooked; Fresh or N/S; Boiled95001790, 210, 1, 0.00%, Grape, wine and sherry-Cooked; Fresh or N/S; CookMeth N/S15003251, 230, 1, 0.00%, Rice, flour-babyfood-Cooked; Dried; Cook Meth N/S21000470, 211, 1, 0.00%, Beef, fat-Cooked; Fresh or N/S; Baked

272

All infantsLow percentile for CEC records: 95 Exposure (mg/day) = 0.014039High percentile for CEC records: 100 Exposure (mg/day) = 0.162091Number of actual records in this interval: 141

Critical foods/foodforms for this population (as derived from these records): N=number of appearances in all records (including duplicates) %=percent of total exposure for all records (including duplicates)

Food, FF, N , Percent, Food Name --------, ---, -----, -------, -------------13020571, 240, 57, 35.81%, Blueberry-babyfood-Cooked; Canned; Cook Meth N/S12002601, 240, 54, 11.23%, Peach-babyfood-Cooked; Canned; Cook Meth N/S12000121, 240, 33, 6.57%, Apricot-babyfood-Cooked; Canned; Cook Meth N/S11000111, 240, 87, 6.06%, Apple, sauce-babyfood-Cooked; Canned; Cook Meth N/S95000190, 212, 3, 5.61%, Asparagus-Cooked; Fresh or N/S; Boiled13020570, 110, 10, 5.09%, Blueberry-Uncooked; Fresh or N/S; Cook Meth N/S11002661, 240, 41, 4.61%, Pear-babyfood-Cooked; Canned; Cook Meth N/S11000081, 240, 77, 3.75%, Apple, peeled fruit-babyfood-Cooked; Canned; CookMeth N/S12000141, 240, 27, 3.52%, Apricot, juice-babyfood-Cooked; Canned; Cook MethN/S13013201, 240, 53, 2.43%, Raspberry-babyfood-Cooked; Canned; Cook Meth N/S 6010431, 240, 32, 2.41%, Bean, snap, succulent-babyfood-Cooked; Canned; CookMeth N/S12002851, 240, 17, 1.06%, Plum-babyfood-Cooked; Canned; Cook Meth N/S13010561, 240, 3, 0.84%, Blackberry, juice-babyfood-Cooked; Canned; CookMeth N/S12002861, 240, 8, 0.74%, Plum, prune, fresh-babyfood-Cooked; Canned; CookMeth N/S11000101, 240, 35, 0.68%, Apple, juice-babyfood-Cooked; Canned; Cook Meth N/S11000110, 212, 6, 0.59%, Apple, sauce-Cooked; Fresh or N/S; Boiled11002681, 240, 10, 0.59%, Pear, juice-babyfood-Cooked; Canned; Cook Meth N/S12002600, 110, 3, 0.55%, Peach-Uncooked; Fresh or N/S; Cook Meth N/S12002300, 110, 1, 0.54%, Nectarine-Uncooked; Fresh or N/S; Cook Meth N/S 9011870, 110, 1, 0.45%, Honeydew melon-Uncooked; Fresh or N/S; Cook MethN/S95001761, 240, 8, 0.45%, Grape, juice-babyfood-Cooked; Canned; Cook Meth N/S12000120, 240, 3, 0.38%, Apricot-Cooked; Canned; Cook Meth N/S12000910, 110, 1, 0.35%, Cherry, juice-Uncooked; Fresh or N/S; Cook Meth N/S 9010750, 110, 2, 0.34%, Cantaloupe-Uncooked; Fresh or N/S; Cook Meth N/S 5021170, 212, 1, 0.30%, Collards-Cooked; Fresh or N/S; Boiled11000100, 110, 15, 0.28%, Apple, juice-Uncooked; Fresh or N/S; Cook Meth N/S12000911, 240, 5, 0.26%, Cherry, juice-babyfood-Cooked; Canned; Cook MethN/S13020570, 214, 1, 0.26%, Blueberry-Cooked; Fresh or N/S; Fried/baked 4020851, 240, 5, 0.22%, Celery-babyfood-Cooked; Canned; Cook Meth N/S12000901, 240, 6, 0.22%, Cherry-babyfood-Cooked; Canned; Cook Meth N/S12002850, 110, 2, 0.21%, Plum-Uncooked; Fresh or N/S; Cook Meth N/S13013211, 240, 3, 0.17%, Raspberry, juice-babyfood-Cooked; Canned; Cook MethN/S95001760, 110, 3, 0.14%, Grape, juice-Uncooked; Fresh or N/S; Cook Meth N/S95003600, 240, 2, 0.13%, Strawberry, juice-Cooked; Canned; Cook Meth N/S13013200, 240, 2, 0.13%, Raspberry-Cooked; Canned; Cook Meth N/S12002881, 240, 2, 0.11%, Plum, prune, juice-babyfood-Cooked; Canned; CookMeth N/S95001760, 240, 3, 0.11%, Grape, juice-Cooked; Canned; Cook Meth N/S12002600, 240, 4, 0.09%, Peach-Cooked; Canned; Cook Meth N/S13010550, 110, 1, 0.09%, Blackberry-Uncooked; Fresh or N/S; Cook Meth N/S95003590, 240, 2, 0.09%, Strawberry-Cooked; Canned; Cook Meth N/S95003590, 110, 3, 0.09%, Strawberry-Uncooked; Fresh or N/S; Cook Meth N/S12000900, 110, 2, 0.09%, Cherry-Uncooked; Fresh or N/S; Cook Meth N/S95001750, 110, 1, 0.08%, Grape-Uncooked; Fresh or N/S; Cook Meth N/S 4020850, 110, 1, 0.08%, Celery-Uncooked; Fresh or N/S; Cook Meth N/S

273

12002880, 110, 1, 0.07%, Plum, prune, juice-Uncooked; Fresh or N/S; CookMeth N/S95003601, 240, 3, 0.07%, Strawberry, juice-babyfood-Cooked; Canned; CookMeth N/S95003600, 210, 1, 0.07%, Strawberry, juice-Cooked; Fresh or N/S; Cook MethN/S95002811, 240, 8, 0.06%, Pineapple, juice-babyfood-Cooked; Canned; Cook MethN/S12000910, 210, 1, 0.06%, Cherry, juice-Cooked; Fresh or N/S; Cook Meth N/S13010550, 240, 2, 0.06%, Blackberry-Cooked; Canned; Cook Meth N/S12002621, 240, 2, 0.06%, Peach, juice-babyfood-Cooked; Canned; Cook Meth N/S95001750, 210, 1, 0.06%, Grape-Cooked; Fresh or N/S; Cook Meth N/S15003251, 230, 8, 0.06%, Rice, flour-babyfood-Cooked; Dried; Cook Meth N/S11002660, 210, 1, 0.05%, Pear-Cooked; Fresh or N/S; Cook Meth N/S 6010430, 242, 3, 0.05%, Bean, snap, succulent-Cooked; Canned; Boiled13013200, 110, 3, 0.05%, Raspberry-Uncooked; Fresh or N/S; Cook Meth N/S11002660, 240, 2, 0.05%, Pear-Cooked; Canned; Cook Meth N/S11000100, 240, 2, 0.04%, Apple, juice-Cooked; Canned; Cook Meth N/S13020570, 211, 2, 0.03%, Blueberry-Cooked; Fresh or N/S; Baked10002410, 110, 2, 0.03%, Orange, juice-Uncooked; Fresh or N/S; Cook Meth N/S13013200, 211, 2, 0.03%, Raspberry-Cooked; Fresh or N/S; Baked11000070, 110, 1, 0.03%, Apple, fruit with peel-Uncooked; Fresh or N/S; CookMeth N/S 6010430, 222, 1, 0.02%, Bean, snap, succulent-Cooked; Frozen; Boiled95003590, 211, 2, 0.02%, Strawberry-Cooked; Fresh or N/S; Baked11002680, 110, 1, 0.02%, Pear, juice-Uncooked; Fresh or N/S; Cook Meth N/S95001750, 240, 3, 0.02%, Grape-Cooked; Canned; Cook Meth N/S10002000, 210, 1, 0.01%, Lemon, juice-Cooked; Fresh or N/S; Cook Meth N/S95002810, 240, 1, 0.01%, Pineapple, juice-Cooked; Canned; Cook Meth N/S 1033000, 212, 2, 0.01%, Potato, tuber, w/o peel-Cooked; Fresh or N/S;Boiled11000091, 230, 1, 0.01%, Apple, dried-babyfood-Cooked; Dried; Cook Meth N/S95002790, 110, 1, 0.01%, Pineapple-Uncooked; Fresh or N/S; Cook Meth N/S10002410, 120, 1, 0.01%, Orange, juice-Uncooked; Frozen; Cook Meth N/S 4020850, 212, 1, 0.01%, Celery-Cooked; Fresh or N/S; Boiled95001760, 210, 1, 0.01%, Grape, juice-Cooked; Fresh or N/S; Cook Meth N/S95001780, 130, 1, 0.01%, Grape, raisin-Uncooked; Dried; Cook Meth N/S10002001, 240, 1, 0.01%, Lemon, juice-babyfood-Cooked; Canned; Cook Meth N/S 1032981, 240, 1, 0.01%, Potato, flour-babyfood-Cooked; Canned; Cook MethN/S15003251, 240, 1, 0.01%, Rice, flour-babyfood-Cooked; Canned; Cook Meth N/S25002931, 240, 1, 0.00%, Pork, fat-babyfood-Cooked; Canned; Cook Meth N/S

274

Nursing infants (<1 yr old)Low percentile for CEC records: 95 Exposure (mg/day) = 0.012265High percentile for CEC records: 100 Exposure (mg/day) = 0.072721Number of actual records in this interval: 41

Critical foods/foodforms for this population (as derived from these records): N=number of appearances in all records (including duplicates) %=percent of total exposure for all records (including duplicates)

Food, FF, N , Percent, Food Name --------, ---, -----, -------, -------------13020571, 240, 15, 41.14%, Blueberry-babyfood-Cooked; Canned; Cook Meth N/S12002601, 240, 17, 14.57%, Peach-babyfood-Cooked; Canned; Cook Meth N/S11000111, 240, 23, 7.09%, Apple, sauce-babyfood-Cooked; Canned; Cook Meth N/S11002661, 240, 11, 4.92%, Pear-babyfood-Cooked; Canned; Cook Meth N/S12000121, 240, 8, 4.48%, Apricot-babyfood-Cooked; Canned; Cook Meth N/S11000081, 240, 20, 3.45%, Apple, peeled fruit-babyfood-Cooked; Canned; CookMeth N/S 6010431, 240, 6, 3.41%, Bean, snap, succulent-babyfood-Cooked; Canned; CookMeth N/S12000141, 240, 8, 3.04%, Apricot, juice-babyfood-Cooked; Canned; Cook MethN/S13020570, 110, 2, 2.90%, Blueberry-Uncooked; Fresh or N/S; Cook Meth N/S12002300, 110, 1, 2.44%, Nectarine-Uncooked; Fresh or N/S; Cook Meth N/S13013201, 240, 13, 1.90%, Raspberry-babyfood-Cooked; Canned; Cook Meth N/S12002600, 110, 2, 1.12%, Peach-Uncooked; Fresh or N/S; Cook Meth N/S11000070, 110, 1, 0.95%, Apple, fruit with peel-Uncooked; Fresh or N/S; CookMeth N/S13010561, 240, 1, 0.92%, Blackberry, juice-babyfood-Cooked; Canned; CookMeth N/S 6010430, 222, 1, 0.76%, Bean, snap, succulent-Cooked; Frozen; Boiled12002861, 240, 4, 0.70%, Plum, prune, fresh-babyfood-Cooked; Canned; CookMeth N/S12002851, 240, 5, 0.69%, Plum-babyfood-Cooked; Canned; Cook Meth N/S11000101, 240, 10, 0.53%, Apple, juice-babyfood-Cooked; Canned; Cook Meth N/S13010550, 110, 1, 0.41%, Blackberry-Uncooked; Fresh or N/S; Cook Meth N/S11000110, 212, 1, 0.39%, Apple, sauce-Cooked; Fresh or N/S; Boiled13013200, 240, 1, 0.34%, Raspberry-Cooked; Canned; Cook Meth N/S11000100, 110, 4, 0.30%, Apple, juice-Uncooked; Fresh or N/S; Cook Meth N/S 4020850, 212, 1, 0.30%, Celery-Cooked; Fresh or N/S; Boiled95003590, 240, 1, 0.23%, Strawberry-Cooked; Canned; Cook Meth N/S13013211, 240, 1, 0.18%, Raspberry, juice-babyfood-Cooked; Canned; Cook MethN/S95001760, 110, 1, 0.16%, Grape, juice-Uncooked; Fresh or N/S; Cook Meth N/S13010550, 240, 1, 0.16%, Blackberry-Cooked; Canned; Cook Meth N/S12002600, 240, 2, 0.16%, Peach-Cooked; Canned; Cook Meth N/S 4013550, 212, 1, 0.15%, Spinach-Cooked; Fresh or N/S; Boiled12000120, 240, 1, 0.10%, Apricot-Cooked; Canned; Cook Meth N/S12000901, 240, 3, 0.09%, Cherry-babyfood-Cooked; Canned; Cook Meth N/S11002681, 240, 1, 0.08%, Pear, juice-babyfood-Cooked; Canned; Cook Meth N/S10002410, 110, 1, 0.08%, Orange, juice-Uncooked; Fresh or N/S; Cook Meth N/S95003601, 240, 1, 0.08%, Strawberry, juice-babyfood-Cooked; Canned; CookMeth N/S95001761, 240, 2, 0.08%, Grape, juice-babyfood-Cooked; Canned; Cook Meth N/S11002660, 240, 1, 0.07%, Pear-Cooked; Canned; Cook Meth N/S13020570, 211, 1, 0.07%, Blueberry-Cooked; Fresh or N/S; Baked13013200, 211, 1, 0.06%, Raspberry-Cooked; Fresh or N/S; Baked 6010430, 212, 1, 0.06%, Bean, snap, succulent-Cooked; Fresh or N/S; Boiled95001750, 240, 2, 0.06%, Grape-Cooked; Canned; Cook Meth N/S10003700, 240, 1, 0.05%, Tangerine, juice-Cooked; Canned; Cook Meth N/S10002000, 240, 1, 0.04%, Lemon, juice-Cooked; Canned; Cook Meth N/S95003590, 211, 1, 0.04%, Strawberry-Cooked; Fresh or N/S; Baked10002070, 240, 1, 0.03%, Lime, juice-Cooked; Canned; Cook Meth N/S15003251, 230, 1, 0.03%, Rice, flour-babyfood-Cooked; Dried; Cook Meth N/S

275

Non-nursing infants (<1 yr old)Low percentile for CEC records: 95 Exposure (mg/day) = 0.014953High percentile for CEC records: 100 Exposure (mg/day) = 0.162091Number of actual records in this interval: 99

Critical foods/foodforms for this population (as derived from these records): N=number of appearances in all records (including duplicates) %=percent of total exposure for all records (including duplicates)

Food, FF, N , Percent, Food Name --------, ---, -----, -------, -------------13020571, 240, 43, 34.98%, Blueberry-babyfood-Cooked; Canned; Cook Meth N/S12002601, 240, 36, 9.86%, Peach-babyfood-Cooked; Canned; Cook Meth N/S95000190, 212, 3, 7.30%, Asparagus-Cooked; Fresh or N/S; Boiled12000121, 240, 25, 7.07%, Apricot-babyfood-Cooked; Canned; Cook Meth N/S13020570, 110, 7, 5.74%, Blueberry-Uncooked; Fresh or N/S; Cook Meth N/S11000111, 240, 64, 5.48%, Apple, sauce-babyfood-Cooked; Canned; Cook Meth N/S11002661, 240, 30, 4.61%, Pear-babyfood-Cooked; Canned; Cook Meth N/S12000141, 240, 19, 3.70%, Apricot, juice-babyfood-Cooked; Canned; Cook MethN/S11000081, 240, 57, 3.70%, Apple, peeled fruit-babyfood-Cooked; Canned; CookMeth N/S13013201, 240, 41, 2.63%, Raspberry-babyfood-Cooked; Canned; Cook Meth N/S 6010431, 240, 29, 2.53%, Bean, snap, succulent-babyfood-Cooked; Canned; CookMeth N/S12002851, 240, 12, 1.17%, Plum-babyfood-Cooked; Canned; Cook Meth N/S12002861, 240, 5, 0.94%, Plum, prune, fresh-babyfood-Cooked; Canned; CookMeth N/S11000101, 240, 24, 0.74%, Apple, juice-babyfood-Cooked; Canned; Cook Meth N/S13010561, 240, 2, 0.74%, Blackberry, juice-babyfood-Cooked; Canned; CookMeth N/S11002681, 240, 8, 0.66%, Pear, juice-babyfood-Cooked; Canned; Cook Meth N/S11000110, 212, 5, 0.65%, Apple, sauce-Cooked; Fresh or N/S; Boiled 9011870, 110, 1, 0.59%, Honeydew melon-Uncooked; Fresh or N/S; Cook MethN/S95001761, 240, 5, 0.51%, Grape, juice-babyfood-Cooked; Canned; Cook Meth N/S12000120, 240, 1, 0.45%, Apricot-Cooked; Canned; Cook Meth N/S12000910, 110, 1, 0.45%, Cherry, juice-Uncooked; Fresh or N/S; Cook Meth N/S 9010750, 110, 2, 0.44%, Cantaloupe-Uncooked; Fresh or N/S; Cook Meth N/S 5021170, 212, 1, 0.39%, Collards-Cooked; Fresh or N/S; Boiled12000911, 240, 5, 0.34%, Cherry, juice-babyfood-Cooked; Canned; Cook MethN/S13020570, 214, 1, 0.33%, Blueberry-Cooked; Fresh or N/S; Fried/baked11000100, 110, 10, 0.27%, Apple, juice-Uncooked; Fresh or N/S; Cook Meth N/S12000901, 240, 3, 0.26%, Cherry-babyfood-Cooked; Canned; Cook Meth N/S12002600, 110, 1, 0.19%, Peach-Uncooked; Fresh or N/S; Cook Meth N/S95003600, 240, 2, 0.16%, Strawberry, juice-Cooked; Canned; Cook Meth N/S 4020851, 240, 3, 0.15%, Celery-babyfood-Cooked; Canned; Cook Meth N/S12002881, 240, 2, 0.15%, Plum, prune, juice-babyfood-Cooked; Canned; CookMeth N/S13013211, 240, 2, 0.15%, Raspberry, juice-babyfood-Cooked; Canned; Cook MethN/S95001760, 240, 3, 0.14%, Grape, juice-Cooked; Canned; Cook Meth N/S12002850, 110, 1, 0.14%, Plum-Uncooked; Fresh or N/S; Cook Meth N/S95003590, 110, 3, 0.11%, Strawberry-Uncooked; Fresh or N/S; Cook Meth N/S12000900, 110, 2, 0.11%, Cherry-Uncooked; Fresh or N/S; Cook Meth N/S12002600, 240, 2, 0.11%, Peach-Cooked; Canned; Cook Meth N/S95001750, 110, 1, 0.11%, Grape-Uncooked; Fresh or N/S; Cook Meth N/S 4020850, 110, 1, 0.10%, Celery-Uncooked; Fresh or N/S; Cook Meth N/S12002880, 110, 1, 0.10%, Plum, prune, juice-Uncooked; Fresh or N/S; CookMeth N/S95002811, 240, 7, 0.08%, Pineapple, juice-babyfood-Cooked; Canned; Cook MethN/S12002621, 240, 2, 0.07%, Peach, juice-babyfood-Cooked; Canned; Cook Meth N/S

276

95001760, 110, 1, 0.07%, Grape, juice-Uncooked; Fresh or N/S; Cook Meth N/S95003601, 240, 2, 0.06%, Strawberry, juice-babyfood-Cooked; Canned; CookMeth N/S 6010430, 242, 2, 0.06%, Bean, snap, succulent-Cooked; Canned; Boiled15003251, 230, 5, 0.05%, Rice, flour-babyfood-Cooked; Dried; Cook Meth N/S13013200, 110, 2, 0.05%, Raspberry-Uncooked; Fresh or N/S; Cook Meth N/S11000100, 240, 2, 0.05%, Apple, juice-Cooked; Canned; Cook Meth N/S 6010430, 222, 1, 0.03%, Bean, snap, succulent-Cooked; Frozen; Boiled11002660, 240, 1, 0.03%, Pear-Cooked; Canned; Cook Meth N/S13020570, 211, 1, 0.02%, Blueberry-Cooked; Fresh or N/S; Baked95002810, 240, 1, 0.02%, Pineapple, juice-Cooked; Canned; Cook Meth N/S13013200, 211, 1, 0.02%, Raspberry-Cooked; Fresh or N/S; Baked11000091, 230, 1, 0.01%, Apple, dried-babyfood-Cooked; Dried; Cook Meth N/S10002410, 110, 1, 0.01%, Orange, juice-Uncooked; Fresh or N/S; Cook Meth N/S95002790, 110, 1, 0.01%, Pineapple-Uncooked; Fresh or N/S; Cook Meth N/S95003590, 211, 1, 0.01%, Strawberry-Cooked; Fresh or N/S; Baked95001750, 240, 1, 0.01%, Grape-Cooked; Canned; Cook Meth N/S 4020850, 212, 1, 0.01%, Celery-Cooked; Fresh or N/S; Boiled95001780, 130, 1, 0.01%, Grape, raisin-Uncooked; Dried; Cook Meth N/S10002001, 240, 1, 0.01%, Lemon, juice-babyfood-Cooked; Canned; Cook Meth N/S15003251, 240, 1, 0.01%, Rice, flour-babyfood-Cooked; Canned; Cook Meth N/S 1033000, 212, 1, 0.01%, Potato, tuber, w/o peel-Cooked; Fresh or N/S;Boiled

277

Females 13+ (preg/not nursing)Low percentile for CEC records: 95 Exposure (mg/day) = 0.004960High percentile for CEC records: 100 Exposure (mg/day) = 0.011075Number of actual records in this interval: 7

Critical foods/foodforms for this population (as derived from these records): N=number of appearances in all records (including duplicates) %=percent of total exposure for all records (including duplicates)

Food, FF, N , Percent, Food Name --------, ---, -----, -------, -------------11000070, 110, 4, 22.44%, Apple, fruit with peel-Uncooked; Fresh or N/S; CookMeth N/S13020570, 110, 1, 18.78%, Blueberry-Uncooked; Fresh or N/S; Cook Meth N/S 4020850, 110, 3, 11.63%, Celery-Uncooked; Fresh or N/S; Cook Meth N/S 9010750, 110, 1, 8.34%, Cantaloupe-Uncooked; Fresh or N/S; Cook Meth N/S13013200, 240, 1, 6.01%, Raspberry-Cooked; Canned; Cook Meth N/S12000140, 240, 1, 5.61%, Apricot, juice-Cooked; Canned; Cook Meth N/S95001750, 110, 2, 5.55%, Grape-Uncooked; Fresh or N/S; Cook Meth N/S95003590, 240, 1, 4.15%, Strawberry-Cooked; Canned; Cook Meth N/S13010550, 240, 1, 2.81%, Blackberry-Cooked; Canned; Cook Meth N/S13020570, 211, 1, 2.29%, Blueberry-Cooked; Fresh or N/S; Baked12000120, 240, 1, 1.74%, Apricot-Cooked; Canned; Cook Meth N/S 4020850, 212, 1, 1.70%, Celery-Cooked; Fresh or N/S; Boiled12002600, 110, 1, 1.68%, Peach-Uncooked; Fresh or N/S; Cook Meth N/S 6010430, 213, 1, 0.97%, Bean, snap, succulent-Cooked; Fresh or N/S; Fried 4020850, 242, 1, 0.95%, Celery-Cooked; Canned; Boiled 4020850, 215, 1, 0.79%, Celery-Cooked; Fresh or N/S; Boiled/baked 8002700, 213, 1, 0.74%, Pepper, bell-Cooked; Fresh or N/S; Fried12002600, 240, 1, 0.57%, Peach-Cooked; Canned; Cook Meth N/S95001750, 240, 1, 0.47%, Grape-Cooked; Canned; Cook Meth N/S 9021350, 110, 1, 0.37%, Cucumber-Uncooked; Fresh or N/S; Cook Meth N/S10002000, 110, 1, 0.29%, Lemon, juice-Uncooked; Fresh or N/S; Cook Meth N/S10002400, 110, 1, 0.28%, Orange-Uncooked; Fresh or N/S; Cook Meth N/S 1033000, 212, 1, 0.23%, Potato, tuber, w/o peel-Cooked; Fresh or N/S;Boiled 8002700, 215, 1, 0.20%, Pepper, bell-Cooked; Fresh or N/S; Boiled/baked

278

Females 13+ (nursing)Low percentile for CEC records: 95 Exposure (mg/day) = 0.004357High percentile for CEC records: 100 Exposure (mg/day) = 0.008470Number of actual records in this interval: 5

Critical foods/foodforms for this population (as derived from these records): N=number of appearances in all records (including duplicates) %=percent of total exposure for all records (including duplicates)

Food, FF, N , Percent, Food Name --------, ---, -----, -------, -------------95003590, 110, 2, 18.43%, Strawberry-Uncooked; Fresh or N/S; Cook Meth N/S95002350, 240, 1, 13.37%, Olive-Cooked; Canned; Cook Meth N/S12002300, 110, 1, 10.11%, Nectarine-Uncooked; Fresh or N/S; Cook Meth N/S95003590, 120, 1, 9.14%, Strawberry-Uncooked; Frozen; Cook Meth N/S12002600, 110, 1, 8.66%, Peach-Uncooked; Fresh or N/S; Cook Meth N/S11000070, 110, 2, 8.52%, Apple, fruit with peel-Uncooked; Fresh or N/S; CookMeth N/S12000130, 130, 1, 8.16%, Apricot, dried-Uncooked; Dried; Cook Meth N/S 9010750, 110, 1, 7.73%, Cantaloupe-Uncooked; Fresh or N/S; Cook Meth N/S 4020850, 110, 1, 3.39%, Celery-Uncooked; Fresh or N/S; Cook Meth N/S95001750, 110, 1, 3.06%, Grape-Uncooked; Fresh or N/S; Cook Meth N/S13013200, 240, 1, 1.18%, Raspberry-Cooked; Canned; Cook Meth N/S12002860, 232, 1, 1.11%, Plum, prune, fresh-Cooked; Dried; Boiled95002350, 211, 1, 1.01%, Olive-Cooked; Fresh or N/S; Baked 9021350, 240, 1, 0.92%, Cucumber-Cooked; Canned; Cook Meth N/S95003590, 240, 1, 0.82%, Strawberry-Cooked; Canned; Cook Meth N/S10002400, 110, 1, 0.69%, Orange-Uncooked; Fresh or N/S; Cook Meth N/S13010550, 240, 1, 0.55%, Blackberry-Cooked; Canned; Cook Meth N/S 4020850, 232, 1, 0.41%, Celery-Cooked; Dried; Boiled12000120, 240, 1, 0.34%, Apricot-Cooked; Canned; Cook Meth N/S10002000, 110, 1, 0.31%, Lemon, juice-Uncooked; Fresh or N/S; Cook Meth N/S15003250, 232, 1, 0.14%, Rice, flour-Cooked; Dried; Boiled

279

Children 1-2 yrsLow percentile for CEC records: 95 Exposure (mg/day) = 0.014194High percentile for CEC records: 100 Exposure (mg/day) = 0.238165Number of actual records in this interval: 223

Critical foods/foodforms for this population (as derived from these records): N=number of appearances in all records (including duplicates) %=percent of total exposure for all records (including duplicates)

Food, FF, N , Percent, Food Name --------, ---, -----, -------, -------------95000190, 242, 12, 13.40%, Asparagus-Cooked; Canned; Boiled13020570, 110, 41, 10.97%, Blueberry-Uncooked; Fresh or N/S; Cook Meth N/S12000130, 130, 6, 5.27%, Apricot, dried-Uncooked; Dried; Cook Meth N/S13020570, 120, 8, 4.85%, Blueberry-Uncooked; Frozen; Cook Meth N/S95003590, 110, 40, 4.69%, Strawberry-Uncooked; Fresh or N/S; Cook Meth N/S95001750, 110, 43, 4.10%, Grape-Uncooked; Fresh or N/S; Cook Meth N/S95002350, 240, 17, 4.02%, Olive-Cooked; Canned; Cook Meth N/S95000190, 212, 5, 3.97%, Asparagus-Cooked; Fresh or N/S; Boiled11000070, 110, 52, 3.83%, Apple, fruit with peel-Uncooked; Fresh or N/S; CookMeth N/S12002600, 240, 37, 2.51%, Peach-Cooked; Canned; Cook Meth N/S 9010750, 110, 27, 2.49%, Cantaloupe-Uncooked; Fresh or N/S; Cook Meth N/S 5021170, 212, 8, 2.46%, Collards-Cooked; Fresh or N/S; Boiled13020570, 211, 27, 2.35%, Blueberry-Cooked; Fresh or N/S; Baked13020571, 240, 9, 2.32%, Blueberry-babyfood-Cooked; Canned; Cook Meth N/S12002300, 110, 11, 2.22%, Nectarine-Uncooked; Fresh or N/S; Cook Meth N/S 4020850, 110, 22, 2.12%, Celery-Uncooked; Fresh or N/S; Cook Meth N/S11002660, 110, 18, 1.63%, Pear-Uncooked; Fresh or N/S; Cook Meth N/S12002600, 110, 19, 1.58%, Peach-Uncooked; Fresh or N/S; Cook Meth N/S13013200, 240, 23, 1.13%, Raspberry-Cooked; Canned; Cook Meth N/S13013210, 110, 3, 1.08%, Raspberry, juice-Uncooked; Fresh or N/S; Cook MethN/S13010561, 240, 6, 1.07%, Blackberry, juice-babyfood-Cooked; Canned; CookMeth N/S11000110, 212, 23, 0.96%, Apple, sauce-Cooked; Fresh or N/S; Boiled11002681, 240, 11, 0.92%, Pear, juice-babyfood-Cooked; Canned; Cook Meth N/S11002660, 240, 18, 0.86%, Pear-Cooked; Canned; Cook Meth N/S 4020850, 212, 22, 0.85%, Celery-Cooked; Fresh or N/S; Boiled13013200, 110, 28, 0.74%, Raspberry-Uncooked; Fresh or N/S; Cook Meth N/S11000100, 110, 55, 0.71%, Apple, juice-Uncooked; Fresh or N/S; Cook Meth N/S95003600, 240, 29, 0.70%, Strawberry, juice-Cooked; Canned; Cook Meth N/S95003590, 240, 22, 0.68%, Strawberry-Cooked; Canned; Cook Meth N/S 6010430, 242, 12, 0.67%, Bean, snap, succulent-Cooked; Canned; Boiled12002601, 240, 8, 0.62%, Peach-babyfood-Cooked; Canned; Cook Meth N/S12000141, 240, 4, 0.59%, Apricot, juice-babyfood-Cooked; Canned; Cook MethN/S11002661, 240, 10, 0.57%, Pear-babyfood-Cooked; Canned; Cook Meth N/S95001760, 110, 20, 0.53%, Grape, juice-Uncooked; Fresh or N/S; Cook Meth N/S12002610, 130, 1, 0.51%, Peach, dried-Uncooked; Dried; Cook Meth N/S11000111, 240, 17, 0.48%, Apple, sauce-babyfood-Cooked; Canned; Cook Meth N/S12002880, 110, 1, 0.40%, Plum, prune, juice-Uncooked; Fresh or N/S; CookMeth N/S12000120, 240, 18, 0.36%, Apricot-Cooked; Canned; Cook Meth N/S13020570, 214, 3, 0.35%, Blueberry-Cooked; Fresh or N/S; Fried/baked13010550, 240, 18, 0.35%, Blackberry-Cooked; Canned; Cook Meth N/S12000140, 240, 2, 0.32%, Apricot, juice-Cooked; Canned; Cook Meth N/S 6010431, 240, 7, 0.31%, Bean, snap, succulent-babyfood-Cooked; Canned; CookMeth N/S 5021170, 242, 2, 0.31%, Collards-Cooked; Canned; Boiled 6010430, 212, 15, 0.31%, Bean, snap, succulent-Cooked; Fresh or N/S; Boiled 8002700, 110, 11, 0.28%, Pepper, bell-Uncooked; Fresh or N/S; Cook Meth N/S95001760, 240, 26, 0.27%, Grape, juice-Cooked; Canned; Cook Meth N/S 5023890, 242, 2, 0.25%, Turnip, greens-Cooked; Canned; Boiled

280

4020850, 210, 11, 0.24%, Celery-Cooked; Fresh or N/S; Cook Meth N/S12000120, 110, 2, 0.24%, Apricot-Uncooked; Fresh or N/S; Cook Meth N/S 4020850, 242, 3, 0.23%, Celery-Cooked; Canned; Boiled95003600, 110, 2, 0.23%, Strawberry, juice-Uncooked; Fresh or N/S; Cook MethN/S 6010430, 222, 7, 0.23%, Bean, snap, succulent-Cooked; Frozen; Boiled13013211, 240, 6, 0.21%, Raspberry, juice-babyfood-Cooked; Canned; Cook MethN/S 4020851, 240, 4, 0.21%, Celery-babyfood-Cooked; Canned; Cook Meth N/S 9011870, 110, 3, 0.20%, Honeydew melon-Uncooked; Fresh or N/S; Cook MethN/S11000081, 240, 12, 0.20%, Apple, peeled fruit-babyfood-Cooked; Canned; CookMeth N/S10002400, 110, 15, 0.20%, Orange-Uncooked; Fresh or N/S; Cook Meth N/S13013201, 240, 9, 0.18%, Raspberry-babyfood-Cooked; Canned; Cook Meth N/S 4020850, 232, 2, 0.18%, Celery-Cooked; Dried; Boiled95003590, 120, 3, 0.17%, Strawberry-Uncooked; Frozen; Cook Meth N/S10002410, 110, 25, 0.17%, Orange, juice-Uncooked; Fresh or N/S; Cook Meth N/S 5022290, 242, 1, 0.16%, Mustard greens-Cooked; Canned; Boiled12000121, 240, 2, 0.15%, Apricot-babyfood-Cooked; Canned; Cook Meth N/S95002350, 215, 1, 0.15%, Olive-Cooked; Fresh or N/S; Boiled/baked95001750, 240, 18, 0.14%, Grape-Cooked; Canned; Cook Meth N/S95003600, 210, 12, 0.13%, Strawberry, juice-Cooked; Fresh or N/S; Cook MethN/S12000910, 110, 1, 0.13%, Cherry, juice-Uncooked; Fresh or N/S; Cook Meth N/S12002850, 110, 3, 0.12%, Plum-Uncooked; Fresh or N/S; Cook Meth N/S 9021350, 110, 7, 0.12%, Cucumber-Uncooked; Fresh or N/S; Cook Meth N/S11000101, 240, 8, 0.11%, Apple, juice-babyfood-Cooked; Canned; Cook Meth N/S12000910, 210, 11, 0.11%, Cherry, juice-Cooked; Fresh or N/S; Cook Meth N/S95001761, 240, 8, 0.11%, Grape, juice-babyfood-Cooked; Canned; Cook Meth N/S13020570, 213, 2, 0.11%, Blueberry-Cooked; Fresh or N/S; Fried12002600, 120, 2, 0.10%, Peach-Uncooked; Frozen; Cook Meth N/S95001750, 210, 11, 0.10%, Grape-Cooked; Fresh or N/S; Cook Meth N/S11002660, 210, 11, 0.10%, Pear-Cooked; Fresh or N/S; Cook Meth N/S12000900, 110, 7, 0.10%, Cherry-Uncooked; Fresh or N/S; Cook Meth N/S95003601, 240, 6, 0.09%, Strawberry, juice-babyfood-Cooked; Canned; CookMeth N/S95001780, 130, 12, 0.09%, Grape, raisin-Uncooked; Dried; Cook Meth N/S95002350, 211, 4, 0.08%, Olive-Cooked; Fresh or N/S; Baked11000100, 240, 9, 0.07%, Apple, juice-Cooked; Canned; Cook Meth N/S12002851, 240, 2, 0.07%, Plum-babyfood-Cooked; Canned; Cook Meth N/S 4020850, 240, 1, 0.07%, Celery-Cooked; Canned; Cook Meth N/S95002810, 110, 5, 0.06%, Pineapple, juice-Uncooked; Fresh or N/S; Cook MethN/S10002410, 120, 8, 0.06%, Orange, juice-Uncooked; Frozen; Cook Meth N/S 4013550, 222, 3, 0.05%, Spinach-Cooked; Frozen; Boiled13020570, 240, 3, 0.05%, Blueberry-Cooked; Canned; Cook Meth N/S12002620, 110, 1, 0.05%, Peach, juice-Uncooked; Fresh or N/S; Cook Meth N/S13013200, 211, 8, 0.05%, Raspberry-Cooked; Fresh or N/S; Baked95002790, 240, 5, 0.05%, Pineapple-Cooked; Canned; Cook Meth N/S12002861, 240, 1, 0.05%, Plum, prune, fresh-babyfood-Cooked; Canned; CookMeth N/S12000901, 240, 3, 0.04%, Cherry-babyfood-Cooked; Canned; Cook Meth N/S11000100, 120, 2, 0.04%, Apple, juice-Uncooked; Frozen; Cook Meth N/S12000900, 240, 8, 0.04%, Cherry-Cooked; Canned; Cook Meth N/S12000130, 211, 2, 0.04%, Apricot, dried-Cooked; Fresh or N/S; Baked11002680, 110, 2, 0.04%, Pear, juice-Uncooked; Fresh or N/S; Cook Meth N/S95002810, 240, 8, 0.03%, Pineapple, juice-Cooked; Canned; Cook Meth N/S10002000, 110, 5, 0.03%, Lemon, juice-Uncooked; Fresh or N/S; Cook Meth N/S 8002700, 213, 2, 0.03%, Pepper, bell-Cooked; Fresh or N/S; Fried 8002700, 210, 3, 0.03%, Pepper, bell-Cooked; Fresh or N/S; Cook Meth N/S10001810, 120, 1, 0.03%, Grapefruit, juice-Uncooked; Frozen; Cook Meth N/S 8002700, 240, 3, 0.03%, Pepper, bell-Cooked; Canned; Cook Meth N/S 4013550, 212, 3, 0.03%, Spinach-Cooked; Fresh or N/S; Boiled11002680, 240, 3, 0.03%, Pear, juice-Cooked; Canned; Cook Meth N/S

281

95003590, 211, 5, 0.02%, Strawberry-Cooked; Fresh or N/S; Baked 8002720, 215, 1, 0.02%, Pepper, nonbell-Cooked; Fresh or N/S; Boiled/baked 4020850, 213, 1, 0.01%, Celery-Cooked; Fresh or N/S; Fried 8002720, 212, 1, 0.01%, Pepper, nonbell-Cooked; Fresh or N/S; Boiled10002000, 120, 1, 0.01%, Lemon, juice-Uncooked; Frozen; Cook Meth N/S12000911, 240, 1, 0.01%, Cherry, juice-babyfood-Cooked; Canned; Cook MethN/S10001810, 110, 1, 0.01%, Grapefruit, juice-Uncooked; Fresh or N/S; Cook MethN/S 8002700, 211, 2, 0.01%, Pepper, bell-Cooked; Fresh or N/S; Baked 5021940, 242, 1, 0.01%, Kale-Cooked; Canned; Boiled 1033000, 212, 2, 0.01%, Potato, tuber, w/o peel-Cooked; Fresh or N/S;Boiled 5020700, 210, 1, 0.01%, Cabbage, Chinese, bok choy-Cooked; Fresh or N/S;Cook Meth N/S12002600, 211, 1, 0.01%, Peach-Cooked; Fresh or N/S; Baked10002000, 210, 2, 0.01%, Lemon, juice-Cooked; Fresh or N/S; Cook Meth N/S 9021350, 240, 1, 0.01%, Cucumber-Cooked; Canned; Cook Meth N/S 8002720, 210, 1, 0.01%, Pepper, nonbell-Cooked; Fresh or N/S; Cook Meth N/S95001780, 210, 2, 0.01%, Grape, raisin-Cooked; Fresh or N/S; Cook Meth N/S15003240, 232, 1, 0.01%, Rice, brown-Cooked; Dried; Boiled 9013990, 110, 1, 0.01%, Watermelon-Uncooked; Fresh or N/S; Cook Meth N/S10003690, 110, 1, 0.01%, Tangerine-Uncooked; Fresh or N/S; Cook Meth N/S 1032990, 212, 1, 0.01%, Potato, tuber, w/peel-Cooked; Fresh or N/S; Boiled 8001480, 214, 1, 0.00%, Eggplant-Cooked; Fresh or N/S; Fried/baked95002811, 240, 1, 0.00%, Pineapple, juice-babyfood-Cooked; Canned; Cook MethN/S12002870, 130, 1, 0.00%, Plum, prune, dried-Uncooked; Dried; Cook Meth N/S 4013550, 215, 1, 0.00%, Spinach-Cooked; Fresh or N/S; Boiled/baked11000090, 211, 1, 0.00%, Apple, dried-Cooked; Fresh or N/S; Baked13010550, 120, 1, 0.00%, Blackberry-Uncooked; Frozen; Cook Meth N/S13013210, 120, 1, 0.00%, Raspberry, juice-Uncooked; Frozen; Cook Meth N/S13010580, 120, 1, 0.00%, Boysenberry-Uncooked; Frozen; Cook Meth N/S10003700, 240, 1, 0.00%, Tangerine, juice-Cooked; Canned; Cook Meth N/S 8002720, 150, 1, 0.00%, Pepper, nonbell-Uncooked; Cured etc; Cook Meth N/S 8002730, 212, 1, 0.00%, Pepper, nonbell, dried-Cooked; Fresh or N/S; Boiled11000090, 230, 1, 0.00%, Apple, dried-Cooked; Dried; Cook Meth N/S

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Children 3-5 yrsLow percentile for CEC records: 95 Exposure (mg/day) = 0.011654High percentile for CEC records: 100 Exposure (mg/day) = 0.149361Number of actual records in this interval: 478

Critical foods/foodforms for this population (as derived from these records): N=number of appearances in all records (including duplicates) %=percent of total exposure for all records (including duplicates)

Food, FF, N , Percent, Food Name --------, ---, -----, -------, -------------13020570, 110, 86, 8.88%, Blueberry-Uncooked; Fresh or N/S; Cook Meth N/S11000070, 110, 190, 8.68%, Apple, fruit with peel-Uncooked; Fresh or N/S; CookMeth N/S95002350, 240, 37, 6.18%, Olive-Cooked; Canned; Cook Meth N/S13020570, 211, 69, 5.84%, Blueberry-Cooked; Fresh or N/S; Baked95001750, 110, 108, 5.61%, Grape-Uncooked; Fresh or N/S; Cook Meth N/S95003590, 110, 79, 5.16%, Strawberry-Uncooked; Fresh or N/S; Cook Meth N/S12002300, 110, 37, 4.93%, Nectarine-Uncooked; Fresh or N/S; Cook Meth N/S95000190, 242, 8, 4.54%, Asparagus-Cooked; Canned; Boiled 9010750, 110, 73, 4.41%, Cantaloupe-Uncooked; Fresh or N/S; Cook Meth N/S95000190, 212, 11, 4.30%, Asparagus-Cooked; Fresh or N/S; Boiled 4020850, 110, 64, 2.59%, Celery-Uncooked; Fresh or N/S; Cook Meth N/S13020570, 120, 14, 2.29%, Blueberry-Uncooked; Frozen; Cook Meth N/S12002600, 240, 89, 2.19%, Peach-Cooked; Canned; Cook Meth N/S13013200, 240, 64, 2.19%, Raspberry-Cooked; Canned; Cook Meth N/S 5021170, 212, 10, 2.07%, Collards-Cooked; Fresh or N/S; Boiled13020570, 214, 24, 1.65%, Blueberry-Cooked; Fresh or N/S; Fried/baked13013200, 110, 56, 1.57%, Raspberry-Uncooked; Fresh or N/S; Cook Meth N/S95003600, 240, 77, 1.48%, Strawberry, juice-Cooked; Canned; Cook Meth N/S95003590, 240, 63, 1.42%, Strawberry-Cooked; Canned; Cook Meth N/S13013210, 110, 10, 1.37%, Raspberry, juice-Uncooked; Fresh or N/S; Cook MethN/S12002600, 110, 27, 1.02%, Peach-Uncooked; Fresh or N/S; Cook Meth N/S11000110, 212, 44, 1.00%, Apple, sauce-Cooked; Fresh or N/S; Boiled12000120, 240, 60, 0.91%, Apricot-Cooked; Canned; Cook Meth N/S12000130, 130, 4, 0.86%, Apricot, dried-Uncooked; Dried; Cook Meth N/S13010550, 240, 58, 0.85%, Blackberry-Cooked; Canned; Cook Meth N/S 6010430, 242, 35, 0.79%, Bean, snap, succulent-Cooked; Canned; Boiled11002660, 240, 27, 0.73%, Pear-Cooked; Canned; Cook Meth N/S11000100, 110, 105, 0.69%, Apple, juice-Uncooked; Fresh or N/S; Cook Meth N/S 4020850, 242, 8, 0.66%, Celery-Cooked; Canned; Boiled11002660, 110, 15, 0.62%, Pear-Uncooked; Fresh or N/S; Cook Meth N/S12000910, 110, 5, 0.59%, Cherry, juice-Uncooked; Fresh or N/S; Cook Meth N/S13021910, 110, 1, 0.59%, Huckleberry-Uncooked; Fresh or N/S; Cook Meth N/S13013200, 120, 5, 0.54%, Raspberry-Uncooked; Frozen; Cook Meth N/S12002850, 110, 16, 0.53%, Plum-Uncooked; Fresh or N/S; Cook Meth N/S95001760, 110, 36, 0.50%, Grape, juice-Uncooked; Fresh or N/S; Cook Meth N/S 5023890, 212, 5, 0.50%, Turnip, greens-Cooked; Fresh or N/S; Boiled 4020850, 212, 31, 0.47%, Celery-Cooked; Fresh or N/S; Boiled 5023890, 242, 4, 0.46%, Turnip, greens-Cooked; Canned; Boiled95001760, 240, 61, 0.41%, Grape, juice-Cooked; Canned; Cook Meth N/S 6010430, 212, 31, 0.41%, Bean, snap, succulent-Cooked; Fresh or N/S; Boiled 4020850, 210, 29, 0.38%, Celery-Cooked; Fresh or N/S; Cook Meth N/S95003600, 110, 5, 0.34%, Strawberry, juice-Uncooked; Fresh or N/S; Cook MethN/S 9011870, 110, 8, 0.33%, Honeydew melon-Uncooked; Fresh or N/S; Cook MethN/S10002400, 110, 37, 0.31%, Orange-Uncooked; Fresh or N/S; Cook Meth N/S95002350, 211, 14, 0.27%, Olive-Cooked; Fresh or N/S; Baked 9021350, 110, 30, 0.26%, Cucumber-Uncooked; Fresh or N/S; Cook Meth N/S12000120, 110, 5, 0.25%, Apricot-Uncooked; Fresh or N/S; Cook Meth N/S95003590, 120, 3, 0.24%, Strawberry-Uncooked; Frozen; Cook Meth N/S

283

95003600, 210, 32, 0.21%, Strawberry, juice-Cooked; Fresh or N/S; Cook MethN/S95001750, 240, 49, 0.21%, Grape-Cooked; Canned; Cook Meth N/S13020570, 213, 5, 0.21%, Blueberry-Cooked; Fresh or N/S; Fried12002620, 110, 2, 0.21%, Peach, juice-Uncooked; Fresh or N/S; Cook Meth N/S10002410, 110, 57, 0.19%, Orange, juice-Uncooked; Fresh or N/S; Cook Meth N/S 5021170, 242, 2, 0.19%, Collards-Cooked; Canned; Boiled12000910, 210, 30, 0.17%, Cherry, juice-Cooked; Fresh or N/S; Cook Meth N/S95001750, 210, 30, 0.17%, Grape-Cooked; Fresh or N/S; Cook Meth N/S 5022290, 212, 3, 0.17%, Mustard greens-Cooked; Fresh or N/S; Boiled 5023890, 222, 1, 0.16%, Turnip, greens-Cooked; Frozen; Boiled 4023220, 240, 1, 0.16%, Rhubarb-Cooked; Canned; Cook Meth N/S11002660, 210, 30, 0.16%, Pear-Cooked; Fresh or N/S; Cook Meth N/S 8002700, 110, 12, 0.15%, Pepper, bell-Uncooked; Fresh or N/S; Cook Meth N/S13010560, 120, 1, 0.15%, Blackberry, juice-Uncooked; Frozen; Cook Meth N/S 6010430, 110, 2, 0.14%, Bean, snap, succulent-Uncooked; Fresh or N/S; CookMeth N/S 9021350, 240, 19, 0.13%, Cucumber-Cooked; Canned; Cook Meth N/S 8002700, 210, 15, 0.13%, Pepper, bell-Cooked; Fresh or N/S; Cook Meth N/S13010550, 120, 2, 0.13%, Blackberry-Uncooked; Frozen; Cook Meth N/S13020571, 240, 2, 0.11%, Blueberry-babyfood-Cooked; Canned; Cook Meth N/S10002000, 110, 18, 0.11%, Lemon, juice-Uncooked; Fresh or N/S; Cook Meth N/S11000100, 240, 28, 0.10%, Apple, juice-Cooked; Canned; Cook Meth N/S 5022290, 242, 1, 0.08%, Mustard greens-Cooked; Canned; Boiled10003690, 110, 6, 0.08%, Tangerine-Uncooked; Fresh or N/S; Cook Meth N/S12000900, 110, 4, 0.08%, Cherry-Uncooked; Fresh or N/S; Cook Meth N/S95001780, 130, 18, 0.08%, Grape, raisin-Uncooked; Dried; Cook Meth N/S10002410, 120, 24, 0.07%, Orange, juice-Uncooked; Frozen; Cook Meth N/S13013210, 240, 3, 0.07%, Raspberry, juice-Cooked; Canned; Cook Meth N/S13010550, 110, 1, 0.07%, Blackberry-Uncooked; Fresh or N/S; Cook Meth N/S13020570, 210, 3, 0.06%, Blueberry-Cooked; Fresh or N/S; Cook Meth N/S 8002340, 210, 2, 0.06%, Okra-Cooked; Fresh or N/S; Cook Meth N/S 5021940, 212, 3, 0.05%, Kale-Cooked; Fresh or N/S; Boiled13020570, 240, 9, 0.05%, Blueberry-Cooked; Canned; Cook Meth N/S11000070, 211, 1, 0.05%, Apple, fruit with peel-Cooked; Fresh or N/S; Baked12002610, 130, 2, 0.05%, Peach, dried-Uncooked; Dried; Cook Meth N/S12000900, 240, 11, 0.04%, Cherry-Cooked; Canned; Cook Meth N/S 8002700, 211, 8, 0.04%, Pepper, bell-Cooked; Fresh or N/S; Baked 5021940, 242, 2, 0.04%, Kale-Cooked; Canned; Boiled 8002700, 213, 6, 0.04%, Pepper, bell-Cooked; Fresh or N/S; Fried95003590, 211, 10, 0.04%, Strawberry-Cooked; Fresh or N/S; Baked 6010430, 222, 4, 0.03%, Bean, snap, succulent-Cooked; Frozen; Boiled11000080, 240, 2, 0.03%, Apple, peeled fruit-Cooked; Canned; Cook Meth N/S13013200, 211, 10, 0.03%, Raspberry-Cooked; Fresh or N/S; Baked95003600, 120, 1, 0.03%, Strawberry, juice-Uncooked; Frozen; Cook Meth N/S95002810, 110, 5, 0.03%, Pineapple, juice-Uncooked; Fresh or N/S; Cook MethN/S 5020700, 210, 3, 0.03%, Cabbage, Chinese, bok choy-Cooked; Fresh or N/S;Cook Meth N/S12002601, 240, 3, 0.03%, Peach-babyfood-Cooked; Canned; Cook Meth N/S95002810, 240, 9, 0.03%, Pineapple, juice-Cooked; Canned; Cook Meth N/S11000111, 240, 3, 0.03%, Apple, sauce-babyfood-Cooked; Canned; Cook Meth N/S95001760, 120, 2, 0.02%, Grape, juice-Uncooked; Frozen; Cook Meth N/S11000100, 120, 4, 0.02%, Apple, juice-Uncooked; Frozen; Cook Meth N/S11002680, 240, 6, 0.02%, Pear, juice-Cooked; Canned; Cook Meth N/S 4020850, 211, 2, 0.02%, Celery-Cooked; Fresh or N/S; Baked 6010430, 213, 3, 0.02%, Bean, snap, succulent-Cooked; Fresh or N/S; Fried13010580, 120, 3, 0.02%, Boysenberry-Uncooked; Frozen; Cook Meth N/S 1033000, 212, 9, 0.02%, Potato, tuber, w/o peel-Cooked; Fresh or N/S;Boiled95002790, 240, 6, 0.02%, Pineapple-Cooked; Canned; Cook Meth N/S11000080, 211, 2, 0.02%, Apple, peeled fruit-Cooked; Fresh or N/S; Baked10002000, 210, 8, 0.02%, Lemon, juice-Cooked; Fresh or N/S; Cook Meth N/S12000900, 120, 2, 0.02%, Cherry-Uncooked; Frozen; Cook Meth N/S10002000, 130, 6, 0.02%, Lemon, juice-Uncooked; Dried; Cook Meth N/S

284

12002600, 120, 2, 0.01%, Peach-Uncooked; Frozen; Cook Meth N/S 9013990, 110, 7, 0.01%, Watermelon-Uncooked; Fresh or N/S; Cook Meth N/S 4020850, 232, 1, 0.01%, Celery-Cooked; Dried; Boiled11000090, 130, 1, 0.01%, Apple, dried-Uncooked; Dried; Cook Meth N/S12000901, 240, 1, 0.01%, Cherry-babyfood-Cooked; Canned; Cook Meth N/S11002670, 130, 1, 0.01%, Pear, dried-Uncooked; Dried; Cook Meth N/S10003700, 240, 2, 0.01%, Tangerine, juice-Cooked; Canned; Cook Meth N/S11002680, 110, 1, 0.01%, Pear, juice-Uncooked; Fresh or N/S; Cook Meth N/S12002860, 110, 1, 0.01%, Plum, prune, fresh-Uncooked; Fresh or N/S; CookMeth N/S12000121, 240, 2, 0.01%, Apricot-babyfood-Cooked; Canned; Cook Meth N/S12000130, 211, 1, 0.01%, Apricot, dried-Cooked; Fresh or N/S; Baked10002000, 240, 2, 0.01%, Lemon, juice-Cooked; Canned; Cook Meth N/S10002070, 240, 2, 0.01%, Lime, juice-Cooked; Canned; Cook Meth N/S 4020850, 213, 2, 0.01%, Celery-Cooked; Fresh or N/S; Fried11002661, 240, 2, 0.01%, Pear-babyfood-Cooked; Canned; Cook Meth N/S12000141, 240, 2, 0.01%, Apricot, juice-babyfood-Cooked; Canned; Cook MethN/S12002600, 211, 1, 0.01%, Peach-Cooked; Fresh or N/S; Baked10001800, 110, 3, 0.01%, Grapefruit-Uncooked; Fresh or N/S; Cook Meth N/S11000110, 240, 2, 0.01%, Apple, sauce-Cooked; Canned; Cook Meth N/S12002870, 130, 2, 0.01%, Plum, prune, dried-Uncooked; Dried; Cook Meth N/S 8002340, 213, 1, 0.01%, Okra-Cooked; Fresh or N/S; Fried 4020850, 215, 1, 0.01%, Celery-Cooked; Fresh or N/S; Boiled/baked 4013550, 222, 1, 0.01%, Spinach-Cooked; Frozen; Boiled95002800, 130, 1, 0.01%, Pineapple, dried-Uncooked; Dried; Cook Meth N/S 8002700, 240, 2, 0.01%, Pepper, bell-Cooked; Canned; Cook Meth N/S10001810, 240, 3, 0.00%, Grapefruit, juice-Cooked; Canned; Cook Meth N/S95003600, 211, 1, 0.00%, Strawberry, juice-Cooked; Fresh or N/S; Baked10002410, 240, 2, 0.00%, Orange, juice-Cooked; Canned; Cook Meth N/S 8002720, 150, 2, 0.00%, Pepper, nonbell-Uncooked; Cured etc; Cook Meth N/S10002000, 120, 1, 0.00%, Lemon, juice-Uncooked; Frozen; Cook Meth N/S25002930, 213, 2, 0.00%, Pork, fat-Cooked; Fresh or N/S; Fried 8002720, 230, 1, 0.00%, Pepper, nonbell-Cooked; Dried; Cook Meth N/S25002930, 210, 1, 0.00%, Pork, fat-Cooked; Fresh or N/S; Cook Meth N/S25002930, 250, 1, 0.00%, Pork, fat-Cooked; Cured etc; Cook Meth N/S 4013550, 211, 1, 0.00%, Spinach-Cooked; Fresh or N/S; Baked13010580, 240, 2, 0.00%, Boysenberry-Cooked; Canned; Cook Meth N/S 6010430, 240, 1, 0.00%, Bean, snap, succulent-Cooked; Canned; Cook Meth N/S95001760, 210, 2, 0.00%, Grape, juice-Cooked; Fresh or N/S; Cook Meth N/S 4013550, 212, 1, 0.00%, Spinach-Cooked; Fresh or N/S; Boiled 1033000, 210, 1, 0.00%, Potato, tuber, w/o peel-Cooked; Fresh or N/S; CookMeth N/S13013201, 240, 1, 0.00%, Raspberry-babyfood-Cooked; Canned; Cook Meth N/S12002851, 240, 1, 0.00%, Plum-babyfood-Cooked; Canned; Cook Meth N/S13013210, 120, 1, 0.00%, Raspberry, juice-Uncooked; Frozen; Cook Meth N/S95002360, 900, 1, 0.00%, Olive, oil-Refined; FF N/A; Cook Meth N/S 8002730, 210, 1, 0.00%, Pepper, nonbell, dried-Cooked; Fresh or N/S; CookMeth N/S 8002700, 215, 1, 0.00%, Pepper, bell-Cooked; Fresh or N/S; Boiled/baked12000140, 120, 1, 0.00%, Apricot, juice-Uncooked; Frozen; Cook Meth N/S95001780, 110, 1, 0.00%, Grape, raisin-Uncooked; Fresh or N/S; Cook Meth N/S 9021350, 150, 1, 0.00%, Cucumber-Uncooked; Cured etc; Cook Meth N/S11000081, 240, 1, 0.00%, Apple, peeled fruit-babyfood-Cooked; Canned; CookMeth N/S12000140, 240, 1, 0.00%, Apricot, juice-Cooked; Canned; Cook Meth N/S11000090, 230, 1, 0.00%, Apple, dried-Cooked; Dried; Cook Meth N/S 1032990, 212, 1, 0.00%, Potato, tuber, w/peel-Cooked; Fresh or N/S; Boiled15001270, 242, 1, 0.00%, Corn, sweet-Cooked; Canned; Boiled15003250, 230, 1, 0.00%, Rice, flour-Cooked; Dried; Cook Meth N/S

285

Children 6-12 yrsLow percentile for CEC records: 95 Exposure (mg/day) = 0.007621High percentile for CEC records: 100 Exposure (mg/day) = 0.214837Number of actual records in this interval: 228

Critical foods/foodforms for this population (as derived from these records): N=number of appearances in all records (including duplicates) %=percent of total exposure for all records (including duplicates)

Food, FF, N , Percent, Food Name --------, ---, -----, -------, -------------95000190, 212, 8, 10.80%, Asparagus-Cooked; Fresh or N/S; Boiled11000070, 110, 82, 8.74%, Apple, fruit with peel-Uncooked; Fresh or N/S; CookMeth N/S95000190, 242, 2, 8.19%, Asparagus-Cooked; Canned; Boiled95002350, 240, 21, 6.00%, Olive-Cooked; Canned; Cook Meth N/S13020570, 110, 22, 5.48%, Blueberry-Uncooked; Fresh or N/S; Cook Meth N/S13020570, 211, 33, 5.34%, Blueberry-Cooked; Fresh or N/S; Baked95003590, 110, 32, 4.70%, Strawberry-Uncooked; Fresh or N/S; Cook Meth N/S 4020850, 110, 39, 4.69%, Celery-Uncooked; Fresh or N/S; Cook Meth N/S12002300, 110, 15, 4.32%, Nectarine-Uncooked; Fresh or N/S; Cook Meth N/S95001750, 110, 32, 3.38%, Grape-Uncooked; Fresh or N/S; Cook Meth N/S 9010750, 110, 33, 3.29%, Cantaloupe-Uncooked; Fresh or N/S; Cook Meth N/S13013200, 240, 37, 2.90%, Raspberry-Cooked; Canned; Cook Meth N/S12002600, 240, 56, 2.36%, Peach-Cooked; Canned; Cook Meth N/S95003590, 240, 37, 1.96%, Strawberry-Cooked; Canned; Cook Meth N/S95000190, 222, 2, 1.64%, Asparagus-Cooked; Frozen; Boiled 6010430, 242, 18, 1.29%, Bean, snap, succulent-Cooked; Canned; Boiled13010550, 240, 36, 1.28%, Blackberry-Cooked; Canned; Cook Meth N/S95003600, 240, 25, 1.10%, Strawberry, juice-Cooked; Canned; Cook Meth N/S12000120, 240, 38, 1.08%, Apricot-Cooked; Canned; Cook Meth N/S 5021170, 212, 4, 0.89%, Collards-Cooked; Fresh or N/S; Boiled11000110, 212, 17, 0.88%, Apple, sauce-Cooked; Fresh or N/S; Boiled95003590, 120, 2, 0.84%, Strawberry-Uncooked; Frozen; Cook Meth N/S13013210, 120, 2, 0.80%, Raspberry, juice-Uncooked; Frozen; Cook Meth N/S11002660, 110, 8, 0.73%, Pear-Uncooked; Fresh or N/S; Cook Meth N/S 4020850, 212, 14, 0.71%, Celery-Cooked; Fresh or N/S; Boiled12000130, 130, 3, 0.67%, Apricot, dried-Uncooked; Dried; Cook Meth N/S12002600, 110, 9, 0.67%, Peach-Uncooked; Fresh or N/S; Cook Meth N/S 4020850, 210, 14, 0.54%, Celery-Cooked; Fresh or N/S; Cook Meth N/S12002850, 110, 5, 0.52%, Plum-Uncooked; Fresh or N/S; Cook Meth N/S13013200, 211, 6, 0.50%, Raspberry-Cooked; Fresh or N/S; Baked11002660, 240, 17, 0.47%, Pear-Cooked; Canned; Cook Meth N/S13013200, 110, 15, 0.47%, Raspberry-Uncooked; Fresh or N/S; Cook Meth N/S12000900, 110, 10, 0.46%, Cherry-Uncooked; Fresh or N/S; Cook Meth N/S95003600, 210, 22, 0.42%, Strawberry, juice-Cooked; Fresh or N/S; Cook MethN/S 5023890, 242, 1, 0.39%, Turnip, greens-Cooked; Canned; Boiled13020570, 214, 4, 0.38%, Blueberry-Cooked; Fresh or N/S; Fried/baked10002400, 110, 18, 0.37%, Orange-Uncooked; Fresh or N/S; Cook Meth N/S 5022290, 242, 1, 0.37%, Mustard greens-Cooked; Canned; Boiled12000910, 210, 22, 0.37%, Cherry, juice-Cooked; Fresh or N/S; Cook Meth N/S13020570, 213, 4, 0.35%, Blueberry-Cooked; Fresh or N/S; Fried95001750, 210, 22, 0.35%, Grape-Cooked; Fresh or N/S; Cook Meth N/S11000100, 110, 29, 0.34%, Apple, juice-Uncooked; Fresh or N/S; Cook Meth N/S 6010430, 212, 11, 0.34%, Bean, snap, succulent-Cooked; Fresh or N/S; Boiled11002660, 210, 22, 0.33%, Pear-Cooked; Fresh or N/S; Cook Meth N/S13010550, 110, 2, 0.32%, Blackberry-Uncooked; Fresh or N/S; Cook Meth N/S12000120, 232, 1, 0.31%, Apricot-Cooked; Dried; Boiled95001750, 240, 34, 0.26%, Grape-Cooked; Canned; Cook Meth N/S 9021350, 240, 13, 0.26%, Cucumber-Cooked; Canned; Cook Meth N/S12000910, 110, 1, 0.24%, Cherry, juice-Uncooked; Fresh or N/S; Cook Meth N/S12000900, 211, 3, 0.23%, Cherry-Cooked; Fresh or N/S; Baked95001760, 240, 24, 0.23%, Grape, juice-Cooked; Canned; Cook Meth N/S

286

12002620, 240, 1, 0.23%, Peach, juice-Cooked; Canned; Cook Meth N/S12000120, 110, 2, 0.23%, Apricot-Uncooked; Fresh or N/S; Cook Meth N/S95002350, 211, 5, 0.22%, Olive-Cooked; Fresh or N/S; Baked 4020850, 242, 1, 0.21%, Celery-Cooked; Canned; Boiled 9011870, 110, 1, 0.21%, Honeydew melon-Uncooked; Fresh or N/S; Cook MethN/S 6010430, 222, 4, 0.20%, Bean, snap, succulent-Cooked; Frozen; Boiled 4020850, 232, 2, 0.19%, Celery-Cooked; Dried; Boiled11000090, 130, 3, 0.18%, Apple, dried-Uncooked; Dried; Cook Meth N/S 8002700, 110, 9, 0.17%, Pepper, bell-Uncooked; Fresh or N/S; Cook Meth N/S 8002700, 210, 3, 0.17%, Pepper, bell-Cooked; Fresh or N/S; Cook Meth N/S13013210, 110, 1, 0.15%, Raspberry, juice-Uncooked; Fresh or N/S; Cook MethN/S10002410, 110, 24, 0.15%, Orange, juice-Uncooked; Fresh or N/S; Cook Meth N/S12002610, 130, 2, 0.15%, Peach, dried-Uncooked; Dried; Cook Meth N/S 9021350, 110, 11, 0.13%, Cucumber-Uncooked; Fresh or N/S; Cook Meth N/S12002620, 110, 1, 0.12%, Peach, juice-Uncooked; Fresh or N/S; Cook Meth N/S95003590, 211, 7, 0.12%, Strawberry-Cooked; Fresh or N/S; Baked11000080, 211, 2, 0.11%, Apple, peeled fruit-Cooked; Fresh or N/S; Baked12000900, 120, 1, 0.10%, Cherry-Uncooked; Frozen; Cook Meth N/S13020570, 210, 2, 0.09%, Blueberry-Cooked; Fresh or N/S; Cook Meth N/S12000130, 211, 2, 0.09%, Apricot, dried-Cooked; Fresh or N/S; Baked95002810, 110, 4, 0.08%, Pineapple, juice-Uncooked; Fresh or N/S; Cook MethN/S12000900, 240, 7, 0.08%, Cherry-Cooked; Canned; Cook Meth N/S 8002700, 240, 4, 0.07%, Pepper, bell-Cooked; Canned; Cook Meth N/S10002000, 110, 7, 0.06%, Lemon, juice-Uncooked; Fresh or N/S; Cook Meth N/S 4020850, 215, 3, 0.06%, Celery-Cooked; Fresh or N/S; Boiled/baked10002000, 210, 8, 0.06%, Lemon, juice-Cooked; Fresh or N/S; Cook Meth N/S95001760, 110, 4, 0.06%, Grape, juice-Uncooked; Fresh or N/S; Cook Meth N/S11000080, 240, 1, 0.05%, Apple, peeled fruit-Cooked; Canned; Cook Meth N/S 8002700, 211, 5, 0.05%, Pepper, bell-Cooked; Fresh or N/S; Baked 1033000, 212, 10, 0.05%, Potato, tuber, w/o peel-Cooked; Fresh or N/S;Boiled10002410, 120, 9, 0.05%, Orange, juice-Uncooked; Frozen; Cook Meth N/S13021360, 110, 1, 0.04%, Currant-Uncooked; Fresh or N/S; Cook Meth N/S95001780, 130, 4, 0.04%, Grape, raisin-Uncooked; Dried; Cook Meth N/S12002870, 130, 3, 0.04%, Plum, prune, dried-Uncooked; Dried; Cook Meth N/S11002670, 130, 2, 0.04%, Pear, dried-Uncooked; Dried; Cook Meth N/S11000100, 240, 7, 0.04%, Apple, juice-Cooked; Canned; Cook Meth N/S 8002700, 213, 5, 0.03%, Pepper, bell-Cooked; Fresh or N/S; Fried13020570, 120, 5, 0.03%, Blueberry-Uncooked; Frozen; Cook Meth N/S 8002720, 212, 1, 0.03%, Pepper, nonbell-Cooked; Fresh or N/S; Boiled13020570, 240, 3, 0.03%, Blueberry-Cooked; Canned; Cook Meth N/S10003700, 240, 5, 0.02%, Tangerine, juice-Cooked; Canned; Cook Meth N/S 8002700, 212, 1, 0.02%, Pepper, bell-Cooked; Fresh or N/S; Boiled95001760, 120, 2, 0.02%, Grape, juice-Uncooked; Frozen; Cook Meth N/S95002790, 110, 2, 0.02%, Pineapple-Uncooked; Fresh or N/S; Cook Meth N/S95001760, 210, 4, 0.02%, Grape, juice-Cooked; Fresh or N/S; Cook Meth N/S 9013990, 110, 3, 0.02%, Watermelon-Uncooked; Fresh or N/S; Cook Meth N/S11000090, 230, 3, 0.02%, Apple, dried-Cooked; Dried; Cook Meth N/S95002350, 213, 1, 0.02%, Olive-Cooked; Fresh or N/S; Fried95002800, 130, 2, 0.02%, Pineapple, dried-Uncooked; Dried; Cook Meth N/S10002000, 130, 4, 0.02%, Lemon, juice-Uncooked; Dried; Cook Meth N/S11000100, 120, 1, 0.02%, Apple, juice-Uncooked; Frozen; Cook Meth N/S10002000, 240, 3, 0.01%, Lemon, juice-Cooked; Canned; Cook Meth N/S12002860, 232, 1, 0.01%, Plum, prune, fresh-Cooked; Dried; Boiled11000080, 213, 1, 0.01%, Apple, peeled fruit-Cooked; Fresh or N/S; Fried 8002700, 215, 2, 0.01%, Pepper, bell-Cooked; Fresh or N/S; Boiled/baked95002790, 240, 2, 0.01%, Pineapple-Cooked; Canned; Cook Meth N/S11000090, 211, 2, 0.01%, Apple, dried-Cooked; Fresh or N/S; Baked10002070, 240, 2, 0.01%, Lime, juice-Cooked; Canned; Cook Meth N/S95002810, 240, 2, 0.01%, Pineapple, juice-Cooked; Canned; Cook Meth N/S10003690, 110, 1, 0.01%, Tangerine-Uncooked; Fresh or N/S; Cook Meth N/S12000910, 240, 1, 0.01%, Cherry, juice-Cooked; Canned; Cook Meth N/S

287

13013210, 240, 1, 0.01%, Raspberry, juice-Cooked; Canned; Cook Meth N/S13010580, 240, 1, 0.01%, Boysenberry-Cooked; Canned; Cook Meth N/S11002680, 240, 1, 0.00%, Pear, juice-Cooked; Canned; Cook Meth N/S15003240, 232, 1, 0.00%, Rice, brown-Cooked; Dried; Boiled10001800, 110, 1, 0.00%, Grapefruit-Uncooked; Fresh or N/S; Cook Meth N/S11000110, 211, 1, 0.00%, Apple, sauce-Cooked; Fresh or N/S; Baked 8003770, 212, 1, 0.00%, Tomato, puree-Cooked; Fresh or N/S; Boiled 1033000, 211, 1, 0.00%, Potato, tuber, w/o peel-Cooked; Fresh or N/S; Baked 1033660, 211, 1, 0.00%, Sweet potato-Cooked; Fresh or N/S; Baked13013200, 120, 1, 0.00%, Raspberry-Uncooked; Frozen; Cook Meth N/S 8002720, 210, 1, 0.00%, Pepper, nonbell-Cooked; Fresh or N/S; Cook Meth N/S

288

Youth 13-19 yrsLow percentile for CEC records: 95 Exposure (mg/day) = 0.004087High percentile for CEC records: 100 Exposure (mg/day) = 0.048055Number of actual records in this interval: 118

Critical foods/foodforms for this population (as derived from these records): N=number of appearances in all records (including duplicates) %=percent of total exposure for all records (including duplicates)

Food, FF, N , Percent, Food Name --------, ---, -----, -------, -------------95002350, 240, 23, 12.11%, Olive-Cooked; Canned; Cook Meth N/S13020570, 211, 24, 10.69%, Blueberry-Cooked; Fresh or N/S; Baked95000190, 212, 3, 8.29%, Asparagus-Cooked; Fresh or N/S; Boiled13020570, 110, 8, 6.66%, Blueberry-Uncooked; Fresh or N/S; Cook Meth N/S 4020850, 110, 28, 6.31%, Celery-Uncooked; Fresh or N/S; Cook Meth N/S 5021170, 212, 7, 4.01%, Collards-Cooked; Fresh or N/S; Boiled11000070, 110, 19, 3.75%, Apple, fruit with peel-Uncooked; Fresh or N/S; CookMeth N/S95003590, 110, 13, 3.34%, Strawberry-Uncooked; Fresh or N/S; Cook Meth N/S13013200, 240, 11, 2.94%, Raspberry-Cooked; Canned; Cook Meth N/S 9010750, 110, 14, 2.74%, Cantaloupe-Uncooked; Fresh or N/S; Cook Meth N/S95003590, 240, 11, 2.03%, Strawberry-Cooked; Canned; Cook Meth N/S13010550, 211, 2, 1.93%, Blackberry-Cooked; Fresh or N/S; Baked95001750, 110, 12, 1.93%, Grape-Uncooked; Fresh or N/S; Cook Meth N/S13013210, 110, 4, 1.81%, Raspberry, juice-Uncooked; Fresh or N/S; Cook MethN/S13020570, 214, 2, 1.49%, Blueberry-Cooked; Fresh or N/S; Fried/baked13010550, 240, 12, 1.39%, Blackberry-Cooked; Canned; Cook Meth N/S12002300, 110, 4, 1.30%, Nectarine-Uncooked; Fresh or N/S; Cook Meth N/S95002350, 211, 6, 1.25%, Olive-Cooked; Fresh or N/S; Baked12002850, 110, 5, 1.24%, Plum-Uncooked; Fresh or N/S; Cook Meth N/S 5021170, 242, 2, 1.13%, Collards-Cooked; Canned; Boiled13020570, 240, 4, 1.10%, Blueberry-Cooked; Canned; Cook Meth N/S 9010800, 110, 1, 1.10%, Casaba-Uncooked; Fresh or N/S; Cook Meth N/S 9011870, 110, 4, 1.03%, Honeydew melon-Uncooked; Fresh or N/S; Cook MethN/S95003600, 240, 9, 1.02%, Strawberry, juice-Cooked; Canned; Cook Meth N/S12002600, 110, 5, 1.01%, Peach-Uncooked; Fresh or N/S; Cook Meth N/S 4020850, 210, 4, 0.94%, Celery-Cooked; Fresh or N/S; Cook Meth N/S 4020850, 232, 1, 0.87%, Celery-Cooked; Dried; Boiled12000120, 240, 11, 0.85%, Apricot-Cooked; Canned; Cook Meth N/S95000190, 242, 1, 0.80%, Asparagus-Cooked; Canned; Boiled 8002700, 110, 17, 0.78%, Pepper, bell-Uncooked; Fresh or N/S; Cook Meth N/S95003600, 110, 3, 0.71%, Strawberry, juice-Uncooked; Fresh or N/S; Cook MethN/S12002600, 240, 14, 0.67%, Peach-Cooked; Canned; Cook Meth N/S 4020850, 212, 9, 0.64%, Celery-Cooked; Fresh or N/S; Boiled12000900, 110, 2, 0.61%, Cherry-Uncooked; Fresh or N/S; Cook Meth N/S13020570, 210, 3, 0.59%, Blueberry-Cooked; Fresh or N/S; Cook Meth N/S 4020850, 215, 3, 0.55%, Celery-Cooked; Fresh or N/S; Boiled/baked 9021350, 110, 9, 0.53%, Cucumber-Uncooked; Fresh or N/S; Cook Meth N/S12000910, 110, 1, 0.49%, Cherry, juice-Uncooked; Fresh or N/S; Cook Meth N/S 4023670, 212, 1, 0.46%, Swiss chard-Cooked; Fresh or N/S; Boiled12002620, 110, 1, 0.45%, Peach, juice-Uncooked; Fresh or N/S; Cook Meth N/S 4020850, 242, 2, 0.42%, Celery-Cooked; Canned; Boiled 5021170, 222, 1, 0.37%, Collards-Cooked; Frozen; Boiled95003590, 211, 3, 0.37%, Strawberry-Cooked; Fresh or N/S; Baked95002350, 212, 1, 0.33%, Olive-Cooked; Fresh or N/S; Boiled11000100, 110, 15, 0.32%, Apple, juice-Uncooked; Fresh or N/S; Cook Meth N/S13020570, 213, 3, 0.25%, Blueberry-Cooked; Fresh or N/S; Fried10002400, 110, 4, 0.24%, Orange-Uncooked; Fresh or N/S; Cook Meth N/S95001750, 240, 11, 0.24%, Grape-Cooked; Canned; Cook Meth N/S 6010430, 242, 2, 0.24%, Bean, snap, succulent-Cooked; Canned; Boiled

289

8002700, 211, 5, 0.21%, Pepper, bell-Cooked; Fresh or N/S; Baked 5020700, 210, 2, 0.19%, Cabbage, Chinese, bok choy-Cooked; Fresh or N/S;Cook Meth N/S95001760, 110, 4, 0.19%, Grape, juice-Uncooked; Fresh or N/S; Cook Meth N/S10002410, 110, 13, 0.17%, Orange, juice-Uncooked; Fresh or N/S; Cook Meth N/S95003600, 210, 4, 0.17%, Strawberry, juice-Cooked; Fresh or N/S; Cook MethN/S13020570, 230, 1, 0.17%, Blueberry-Cooked; Dried; Cook Meth N/S12000910, 210, 4, 0.15%, Cherry, juice-Cooked; Fresh or N/S; Cook Meth N/S 6010430, 212, 3, 0.14%, Bean, snap, succulent-Cooked; Fresh or N/S; Boiled95001750, 210, 4, 0.14%, Grape-Cooked; Fresh or N/S; Cook Meth N/S 8002700, 215, 2, 0.14%, Pepper, bell-Cooked; Fresh or N/S; Boiled/baked11002660, 210, 4, 0.13%, Pear-Cooked; Fresh or N/S; Cook Meth N/S11000110, 212, 2, 0.13%, Apple, sauce-Cooked; Fresh or N/S; Boiled 5021940, 212, 3, 0.12%, Kale-Cooked; Fresh or N/S; Boiled 5020700, 150, 1, 0.12%, Cabbage, Chinese, bok choy-Uncooked; Cured etc;Cook Meth N/S12002600, 211, 2, 0.12%, Peach-Cooked; Fresh or N/S; Baked12000130, 211, 2, 0.11%, Apricot, dried-Cooked; Fresh or N/S; Baked 4020850, 211, 2, 0.11%, Celery-Cooked; Fresh or N/S; Baked 8002720, 110, 1, 0.10%, Pepper, nonbell-Uncooked; Fresh or N/S; Cook MethN/S 9021350, 240, 3, 0.08%, Cucumber-Cooked; Canned; Cook Meth N/S95001760, 240, 5, 0.08%, Grape, juice-Cooked; Canned; Cook Meth N/S10001810, 110, 2, 0.07%, Grapefruit, juice-Uncooked; Fresh or N/S; Cook MethN/S 1033000, 212, 4, 0.06%, Potato, tuber, w/o peel-Cooked; Fresh or N/S;Boiled13020570, 120, 3, 0.06%, Blueberry-Uncooked; Frozen; Cook Meth N/S95001790, 110, 1, 0.06%, Grape, wine and sherry-Uncooked; Fresh or N/S; CookMeth N/S13013200, 211, 5, 0.06%, Raspberry-Cooked; Fresh or N/S; Baked11000090, 230, 1, 0.06%, Apple, dried-Cooked; Dried; Cook Meth N/S11002660, 110, 1, 0.05%, Pear-Uncooked; Fresh or N/S; Cook Meth N/S 8002720, 210, 2, 0.05%, Pepper, nonbell-Cooked; Fresh or N/S; Cook Meth N/S10002410, 120, 4, 0.05%, Orange, juice-Uncooked; Frozen; Cook Meth N/S 8002700, 210, 2, 0.05%, Pepper, bell-Cooked; Fresh or N/S; Cook Meth N/S11000080, 211, 1, 0.04%, Apple, peeled fruit-Cooked; Fresh or N/S; Baked10002000, 110, 4, 0.04%, Lemon, juice-Uncooked; Fresh or N/S; Cook Meth N/S11002660, 240, 2, 0.04%, Pear-Cooked; Canned; Cook Meth N/S 8002340, 240, 1, 0.03%, Okra-Cooked; Canned; Cook Meth N/S10002000, 210, 3, 0.03%, Lemon, juice-Cooked; Fresh or N/S; Cook Meth N/S 9013990, 110, 2, 0.03%, Watermelon-Uncooked; Fresh or N/S; Cook Meth N/S95002810, 110, 1, 0.02%, Pineapple, juice-Uncooked; Fresh or N/S; Cook MethN/S13013200, 110, 2, 0.02%, Raspberry-Uncooked; Fresh or N/S; Cook Meth N/S12000910, 240, 1, 0.02%, Cherry, juice-Cooked; Canned; Cook Meth N/S 1032990, 212, 2, 0.02%, Potato, tuber, w/peel-Cooked; Fresh or N/S; Boiled 8002700, 212, 1, 0.02%, Pepper, bell-Cooked; Fresh or N/S; Boiled13013200, 120, 2, 0.02%, Raspberry-Uncooked; Frozen; Cook Meth N/S 8002700, 150, 1, 0.02%, Pepper, bell-Uncooked; Cured etc; Cook Meth N/S95003600, 211, 1, 0.02%, Strawberry, juice-Cooked; Fresh or N/S; Baked95001780, 210, 1, 0.02%, Grape, raisin-Cooked; Fresh or N/S; Cook Meth N/S11000090, 211, 2, 0.02%, Apple, dried-Cooked; Fresh or N/S; Baked13013210, 240, 1, 0.02%, Raspberry, juice-Cooked; Canned; Cook Meth N/S13010580, 240, 1, 0.02%, Boysenberry-Cooked; Canned; Cook Meth N/S 4013550, 212, 1, 0.02%, Spinach-Cooked; Fresh or N/S; Boiled 8002720, 240, 2, 0.01%, Pepper, nonbell-Cooked; Canned; Cook Meth N/S13010550, 110, 1, 0.01%, Blackberry-Uncooked; Fresh or N/S; Cook Meth N/S13010580, 110, 1, 0.01%, Boysenberry-Uncooked; Fresh or N/S; Cook Meth N/S12000140, 240, 1, 0.01%, Apricot, juice-Cooked; Canned; Cook Meth N/S 8002720, 215, 1, 0.01%, Pepper, nonbell-Cooked; Fresh or N/S; Boiled/baked12000140, 110, 1, 0.01%, Apricot, juice-Uncooked; Fresh or N/S; Cook MethN/S 8003750, 215, 1, 0.01%, Tomato-Cooked; Fresh or N/S; Boiled/baked

290

4013550, 110, 1, 0.01%, Spinach-Uncooked; Fresh or N/S; Cook Meth N/S95001780, 130, 1, 0.01%, Grape, raisin-Uncooked; Dried; Cook Meth N/S 8002700, 221, 1, 0.01%, Pepper, bell-Cooked; Frozen; Baked10001800, 110, 1, 0.01%, Grapefruit-Uncooked; Fresh or N/S; Cook Meth N/S10002000, 130, 1, 0.01%, Lemon, juice-Uncooked; Dried; Cook Meth N/S10003700, 240, 1, 0.01%, Tangerine, juice-Cooked; Canned; Cook Meth N/S10003700, 110, 1, 0.01%, Tangerine, juice-Uncooked; Fresh or N/S; Cook MethN/S95003600, 213, 1, 0.01%, Strawberry, juice-Cooked; Fresh or N/S; Fried95001780, 230, 1, 0.01%, Grape, raisin-Cooked; Dried; Cook Meth N/S11002680, 240, 1, 0.01%, Pear, juice-Cooked; Canned; Cook Meth N/S10002000, 240, 1, 0.01%, Lemon, juice-Cooked; Canned; Cook Meth N/S95001760, 210, 1, 0.01%, Grape, juice-Cooked; Fresh or N/S; Cook Meth N/S95002790, 110, 1, 0.01%, Pineapple-Uncooked; Fresh or N/S; Cook Meth N/S11002680, 110, 1, 0.01%, Pear, juice-Uncooked; Fresh or N/S; Cook Meth N/S11000110, 211, 1, 0.01%, Apple, sauce-Cooked; Fresh or N/S; Baked10002070, 240, 1, 0.01%, Lime, juice-Cooked; Canned; Cook Meth N/S15001240, 240, 1, 0.01%, Corn, field, syrup-Cooked; Canned; Cook Meth N/S12000900, 240, 1, 0.01%, Cherry-Cooked; Canned; Cook Meth N/S10002070, 110, 1, 0.01%, Lime, juice-Uncooked; Fresh or N/S; Cook Meth N/S

291

Adults 20-49 yrsLow percentile for CEC records: 95 Exposure (mg/day) = 0.004308High percentile for CEC records: 100 Exposure (mg/day) = 0.096606Number of actual records in this interval: 433

Critical foods/foodforms for this population (as derived from these records): N=number of appearances in all records (including duplicates) %=percent of total exposure for all records (including duplicates)

Food, FF, N , Percent, Food Name --------, ---, -----, -------, -------------95000190, 212, 34, 18.24%, Asparagus-Cooked; Fresh or N/S; Boiled95000190, 242, 15, 12.05%, Asparagus-Cooked; Canned; Boiled95002350, 240, 80, 8.26%, Olive-Cooked; Canned; Cook Meth N/S13020570, 110, 66, 7.69%, Blueberry-Uncooked; Fresh or N/S; Cook Meth N/S13020570, 211, 54, 5.27%, Blueberry-Cooked; Fresh or N/S; Baked 4020850, 110, 95, 4.24%, Celery-Uncooked; Fresh or N/S; Cook Meth N/S12002300, 110, 48, 4.07%, Nectarine-Uncooked; Fresh or N/S; Cook Meth N/S11000070, 110, 101, 3.12%, Apple, fruit with peel-Uncooked; Fresh or N/S; CookMeth N/S95003590, 110, 60, 2.95%, Strawberry-Uncooked; Fresh or N/S; Cook Meth N/S95000190, 222, 7, 2.75%, Asparagus-Cooked; Frozen; Boiled 9010750, 110, 56, 2.66%, Cantaloupe-Uncooked; Fresh or N/S; Cook Meth N/S13013200, 240, 48, 1.88%, Raspberry-Cooked; Canned; Cook Meth N/S95001750, 110, 46, 1.64%, Grape-Uncooked; Fresh or N/S; Cook Meth N/S13013200, 110, 37, 1.35%, Raspberry-Uncooked; Fresh or N/S; Cook Meth N/S 5021170, 212, 13, 1.30%, Collards-Cooked; Fresh or N/S; Boiled95003590, 240, 47, 1.16%, Strawberry-Cooked; Canned; Cook Meth N/S 5023890, 212, 11, 1.02%, Turnip, greens-Cooked; Fresh or N/S; Boiled13020570, 120, 9, 1.00%, Blueberry-Uncooked; Frozen; Cook Meth N/S 4020850, 212, 56, 0.82%, Celery-Cooked; Fresh or N/S; Boiled12002600, 110, 23, 0.77%, Peach-Uncooked; Fresh or N/S; Cook Meth N/S 8002700, 110, 48, 0.74%, Pepper, bell-Uncooked; Fresh or N/S; Cook Meth N/S 4020850, 210, 18, 0.70%, Celery-Cooked; Fresh or N/S; Cook Meth N/S 8002700, 210, 22, 0.66%, Pepper, bell-Cooked; Fresh or N/S; Cook Meth N/S12000130, 130, 7, 0.64%, Apricot, dried-Uncooked; Dried; Cook Meth N/S13010550, 240, 45, 0.61%, Blackberry-Cooked; Canned; Cook Meth N/S12000120, 240, 45, 0.60%, Apricot-Cooked; Canned; Cook Meth N/S 9011870, 110, 22, 0.57%, Honeydew melon-Uncooked; Fresh or N/S; Cook MethN/S13020570, 213, 6, 0.43%, Blueberry-Cooked; Fresh or N/S; Fried11002660, 110, 15, 0.43%, Pear-Uncooked; Fresh or N/S; Cook Meth N/S13020570, 240, 6, 0.40%, Blueberry-Cooked; Canned; Cook Meth N/S 5022290, 212, 6, 0.40%, Mustard greens-Cooked; Fresh or N/S; Boiled95002350, 211, 17, 0.39%, Olive-Cooked; Fresh or N/S; Baked13010550, 120, 3, 0.35%, Blackberry-Uncooked; Frozen; Cook Meth N/S 4023220, 240, 1, 0.32%, Rhubarb-Cooked; Canned; Cook Meth N/S13010550, 211, 1, 0.31%, Blackberry-Cooked; Fresh or N/S; Baked12002880, 110, 5, 0.31%, Plum, prune, juice-Uncooked; Fresh or N/S; CookMeth N/S95000190, 110, 1, 0.30%, Asparagus-Uncooked; Fresh or N/S; Cook Meth N/S95001790, 110, 36, 0.30%, Grape, wine and sherry-Uncooked; Fresh or N/S; CookMeth N/S 4023220, 211, 2, 0.29%, Rhubarb-Cooked; Fresh or N/S; Baked95003600, 240, 25, 0.27%, Strawberry, juice-Cooked; Canned; Cook Meth N/S 6010430, 212, 24, 0.27%, Bean, snap, succulent-Cooked; Fresh or N/S; Boiled 5023890, 222, 1, 0.26%, Turnip, greens-Cooked; Frozen; Boiled 6010430, 242, 11, 0.25%, Bean, snap, succulent-Cooked; Canned; Boiled12002600, 240, 40, 0.25%, Peach-Cooked; Canned; Cook Meth N/S13013210, 110, 5, 0.25%, Raspberry, juice-Uncooked; Fresh or N/S; Cook MethN/S13013200, 120, 7, 0.24%, Raspberry-Uncooked; Frozen; Cook Meth N/S13013200, 211, 6, 0.24%, Raspberry-Cooked; Fresh or N/S; Baked11000070, 211, 2, 0.23%, Apple, fruit with peel-Cooked; Fresh or N/S; Baked

292

10002400, 110, 35, 0.23%, Orange-Uncooked; Fresh or N/S; Cook Meth N/S 5020700, 150, 6, 0.22%, Cabbage, Chinese, bok choy-Uncooked; Cured etc;Cook Meth N/S13010550, 110, 4, 0.21%, Blackberry-Uncooked; Fresh or N/S; Cook Meth N/S11000080, 211, 8, 0.20%, Apple, peeled fruit-Cooked; Fresh or N/S; Baked 8002720, 110, 9, 0.20%, Pepper, nonbell-Uncooked; Fresh or N/S; Cook MethN/S95003600, 110, 4, 0.20%, Strawberry, juice-Uncooked; Fresh or N/S; Cook MethN/S13020570, 214, 4, 0.19%, Blueberry-Cooked; Fresh or N/S; Fried/baked12002850, 110, 12, 0.18%, Plum-Uncooked; Fresh or N/S; Cook Meth N/S95003590, 120, 4, 0.16%, Strawberry-Uncooked; Frozen; Cook Meth N/S12000140, 240, 4, 0.15%, Apricot, juice-Cooked; Canned; Cook Meth N/S 9021350, 110, 31, 0.15%, Cucumber-Uncooked; Fresh or N/S; Cook Meth N/S 4020850, 242, 6, 0.14%, Celery-Cooked; Canned; Boiled10002410, 110, 42, 0.13%, Orange, juice-Uncooked; Fresh or N/S; Cook Meth N/S12000900, 110, 5, 0.11%, Cherry-Uncooked; Fresh or N/S; Cook Meth N/S 5021170, 222, 1, 0.10%, Collards-Cooked; Frozen; Boiled 4020850, 232, 8, 0.10%, Celery-Cooked; Dried; Boiled95001760, 110, 8, 0.10%, Grape, juice-Uncooked; Fresh or N/S; Cook Meth N/S12002620, 240, 3, 0.09%, Peach, juice-Cooked; Canned; Cook Meth N/S 5022290, 242, 1, 0.09%, Mustard greens-Cooked; Canned; Boiled10002000, 110, 27, 0.09%, Lemon, juice-Uncooked; Fresh or N/S; Cook Meth N/S95001750, 240, 26, 0.09%, Grape-Cooked; Canned; Cook Meth N/S 5020700, 210, 7, 0.08%, Cabbage, Chinese, bok choy-Cooked; Fresh or N/S;Cook Meth N/S12000120, 110, 2, 0.08%, Apricot-Uncooked; Fresh or N/S; Cook Meth N/S13010560, 110, 1, 0.08%, Blackberry, juice-Uncooked; Fresh or N/S; Cook MethN/S 5022290, 222, 1, 0.08%, Mustard greens-Cooked; Frozen; Boiled95002350, 212, 1, 0.07%, Olive-Cooked; Fresh or N/S; Boiled 8002700, 211, 15, 0.07%, Pepper, bell-Cooked; Fresh or N/S; Baked 9021350, 240, 21, 0.06%, Cucumber-Cooked; Canned; Cook Meth N/S11000110, 212, 5, 0.06%, Apple, sauce-Cooked; Fresh or N/S; Boiled12002600, 211, 3, 0.06%, Peach-Cooked; Fresh or N/S; Baked 6010430, 222, 5, 0.06%, Bean, snap, succulent-Cooked; Frozen; Boiled13010580, 110, 2, 0.06%, Boysenberry-Uncooked; Fresh or N/S; Cook Meth N/S95003590, 211, 4, 0.05%, Strawberry-Cooked; Fresh or N/S; Baked 6010430, 213, 5, 0.05%, Bean, snap, succulent-Cooked; Fresh or N/S; Fried13010580, 120, 2, 0.05%, Boysenberry-Uncooked; Frozen; Cook Meth N/S12002600, 120, 3, 0.05%, Peach-Uncooked; Frozen; Cook Meth N/S11000100, 110, 10, 0.05%, Apple, juice-Uncooked; Fresh or N/S; Cook Meth N/S 8002720, 240, 5, 0.05%, Pepper, nonbell-Cooked; Canned; Cook Meth N/S10001810, 110, 6, 0.05%, Grapefruit, juice-Uncooked; Fresh or N/S; Cook MethN/S 8002700, 150, 7, 0.05%, Pepper, bell-Uncooked; Cured etc; Cook Meth N/S 5021940, 212, 6, 0.04%, Kale-Cooked; Fresh or N/S; Boiled 8002700, 213, 4, 0.04%, Pepper, bell-Cooked; Fresh or N/S; Fried12000120, 211, 1, 0.04%, Apricot-Cooked; Fresh or N/S; Baked 8002700, 212, 3, 0.04%, Pepper, bell-Cooked; Fresh or N/S; Boiled12002620, 110, 1, 0.04%, Peach, juice-Uncooked; Fresh or N/S; Cook Meth N/S95001760, 240, 10, 0.04%, Grape, juice-Cooked; Canned; Cook Meth N/S12000900, 120, 1, 0.04%, Cherry-Uncooked; Frozen; Cook Meth N/S10002410, 120, 12, 0.03%, Orange, juice-Uncooked; Frozen; Cook Meth N/S11000070, 213, 1, 0.03%, Apple, fruit with peel-Cooked; Fresh or N/S; Fried10001800, 110, 10, 0.03%, Grapefruit-Uncooked; Fresh or N/S; Cook Meth N/S13021360, 110, 2, 0.03%, Currant-Uncooked; Fresh or N/S; Cook Meth N/S13013210, 240, 2, 0.03%, Raspberry, juice-Cooked; Canned; Cook Meth N/S12000900, 211, 6, 0.03%, Cherry-Cooked; Fresh or N/S; Baked13020570, 210, 2, 0.03%, Blueberry-Cooked; Fresh or N/S; Cook Meth N/S95001780, 130, 5, 0.03%, Grape, raisin-Uncooked; Dried; Cook Meth N/S13020570, 230, 1, 0.02%, Blueberry-Cooked; Dried; Cook Meth N/S 8002720, 150, 6, 0.02%, Pepper, nonbell-Uncooked; Cured etc; Cook Meth N/S 8002720, 210, 5, 0.02%, Pepper, nonbell-Cooked; Fresh or N/S; Cook Meth N/S

293

95002810, 110, 2, 0.02%, Pineapple, juice-Uncooked; Fresh or N/S; Cook MethN/S 8002340, 210, 2, 0.02%, Okra-Cooked; Fresh or N/S; Cook Meth N/S12000130, 211, 2, 0.02%, Apricot, dried-Cooked; Fresh or N/S; Baked10002070, 110, 4, 0.02%, Lime, juice-Uncooked; Fresh or N/S; Cook Meth N/S 4020850, 215, 2, 0.02%, Celery-Cooked; Fresh or N/S; Boiled/baked 6010430, 110, 2, 0.01%, Bean, snap, succulent-Uncooked; Fresh or N/S; CookMeth N/S 1033000, 212, 8, 0.01%, Potato, tuber, w/o peel-Cooked; Fresh or N/S;Boiled11000080, 221, 2, 0.01%, Apple, peeled fruit-Cooked; Frozen; Baked12002860, 232, 2, 0.01%, Plum, prune, fresh-Cooked; Dried; Boiled95002790, 240, 6, 0.01%, Pineapple-Cooked; Canned; Cook Meth N/S95002350, 221, 1, 0.01%, Olive-Cooked; Frozen; Baked 5020700, 110, 1, 0.01%, Cabbage, Chinese, bok choy-Uncooked; Fresh or N/S;Cook Meth N/S12002860, 211, 2, 0.01%, Plum, prune, fresh-Cooked; Fresh or N/S; Baked12000900, 210, 1, 0.01%, Cherry-Cooked; Fresh or N/S; Cook Meth N/S11002680, 110, 2, 0.01%, Pear, juice-Uncooked; Fresh or N/S; Cook Meth N/S12002610, 130, 1, 0.01%, Peach, dried-Uncooked; Dried; Cook Meth N/S 9013990, 110, 4, 0.01%, Watermelon-Uncooked; Fresh or N/S; Cook Meth N/S11000090, 211, 3, 0.01%, Apple, dried-Cooked; Fresh or N/S; Baked 4020850, 211, 2, 0.01%, Celery-Cooked; Fresh or N/S; Baked11002660, 240, 2, 0.01%, Pear-Cooked; Canned; Cook Meth N/S12000900, 240, 3, 0.01%, Cherry-Cooked; Canned; Cook Meth N/S 9020210, 212, 1, 0.01%, Balsam pear-Cooked; Fresh or N/S; Boiled10001810, 240, 2, 0.01%, Grapefruit, juice-Cooked; Canned; Cook Meth N/S 8001480, 212, 2, 0.01%, Eggplant-Cooked; Fresh or N/S; Boiled 6010430, 240, 2, 0.01%, Bean, snap, succulent-Cooked; Canned; Cook Meth N/S10002000, 240, 2, 0.01%, Lemon, juice-Cooked; Canned; Cook Meth N/S11002680, 240, 2, 0.01%, Pear, juice-Cooked; Canned; Cook Meth N/S11000080, 213, 3, 0.01%, Apple, peeled fruit-Cooked; Fresh or N/S; Fried10001810, 120, 1, 0.01%, Grapefruit, juice-Uncooked; Frozen; Cook Meth N/S 1032990, 212, 4, 0.01%, Potato, tuber, w/peel-Cooked; Fresh or N/S; Boiled12000140, 110, 2, 0.01%, Apricot, juice-Uncooked; Fresh or N/S; Cook MethN/S10003690, 110, 2, 0.01%, Tangerine-Uncooked; Fresh or N/S; Cook Meth N/S 4013550, 110, 3, 0.01%, Spinach-Uncooked; Fresh or N/S; Cook Meth N/S95002790, 110, 3, 0.01%, Pineapple-Uncooked; Fresh or N/S; Cook Meth N/S 4013550, 212, 3, 0.01%, Spinach-Cooked; Fresh or N/S; Boiled10002000, 130, 1, 0.01%, Lemon, juice-Uncooked; Dried; Cook Meth N/S11000100, 240, 3, 0.01%, Apple, juice-Cooked; Canned; Cook Meth N/S10001990, 110, 2, 0.01%, Lemon-Uncooked; Fresh or N/S; Cook Meth N/S95003600, 210, 1, 0.00%, Strawberry, juice-Cooked; Fresh or N/S; Cook MethN/S 8002700, 215, 2, 0.00%, Pepper, bell-Cooked; Fresh or N/S; Boiled/baked12000910, 210, 1, 0.00%, Cherry, juice-Cooked; Fresh or N/S; Cook Meth N/S12002870, 130, 1, 0.00%, Plum, prune, dried-Uncooked; Dried; Cook Meth N/S95001750, 210, 1, 0.00%, Grape-Cooked; Fresh or N/S; Cook Meth N/S95001750, 120, 1, 0.00%, Grape-Uncooked; Frozen; Cook Meth N/S11002660, 210, 1, 0.00%, Pear-Cooked; Fresh or N/S; Cook Meth N/S15003240, 232, 2, 0.00%, Rice, brown-Cooked; Dried; Boiled11000090, 130, 1, 0.00%, Apple, dried-Uncooked; Dried; Cook Meth N/S10002070, 120, 2, 0.00%, Lime, juice-Uncooked; Frozen; Cook Meth N/S11002670, 130, 1, 0.00%, Pear, dried-Uncooked; Dried; Cook Meth N/S10003700, 110, 1, 0.00%, Tangerine, juice-Uncooked; Fresh or N/S; Cook MethN/S95000730, 110, 1, 0.00%, Cactus-Uncooked; Fresh or N/S; Cook Meth N/S11000110, 240, 1, 0.00%, Apple, sauce-Cooked; Canned; Cook Meth N/S 8002700, 221, 1, 0.00%, Pepper, bell-Cooked; Frozen; Baked10003700, 240, 1, 0.00%, Tangerine, juice-Cooked; Canned; Cook Meth N/S 1033660, 215, 2, 0.00%, Sweet potato-Cooked; Fresh or N/S; Boiled/baked13013210, 120, 1, 0.00%, Raspberry, juice-Uncooked; Frozen; Cook Meth N/S 8003770, 210, 1, 0.00%, Tomato, puree-Cooked; Fresh or N/S; Cook Meth N/S10002070, 240, 1, 0.00%, Lime, juice-Cooked; Canned; Cook Meth N/S

294

9021350, 212, 1, 0.00%, Cucumber-Cooked; Fresh or N/S; Boiled12000910, 110, 1, 0.00%, Cherry, juice-Uncooked; Fresh or N/S; Cook Meth N/S25002930, 210, 1, 0.00%, Pork, fat-Cooked; Fresh or N/S; Cook Meth N/S12000140, 120, 1, 0.00%, Apricot, juice-Uncooked; Frozen; Cook Meth N/S 8001480, 213, 1, 0.00%, Eggplant-Cooked; Fresh or N/S; Fried95002810, 120, 1, 0.00%, Pineapple, juice-Uncooked; Frozen; Cook Meth N/S95002790, 210, 1, 0.00%, Pineapple-Cooked; Fresh or N/S; Cook Meth N/S13010580, 240, 1, 0.00%, Boysenberry-Cooked; Canned; Cook Meth N/S95002810, 240, 1, 0.00%, Pineapple, juice-Cooked; Canned; Cook Meth N/S10002000, 211, 1, 0.00%, Lemon, juice-Cooked; Fresh or N/S; Baked10003700, 120, 1, 0.00%, Tangerine, juice-Uncooked; Frozen; Cook Meth N/S15003250, 232, 1, 0.00%, Rice, flour-Cooked; Dried; Boiled

295

Adults 50+ yrsLow percentile for CEC records: 95 Exposure (mg/day) = 0.005239High percentile for CEC records: 100 Exposure (mg/day) = 0.085045Number of actual records in this interval: 450

Critical foods/foodforms for this population (as derived from these records): N=number of appearances in all records (including duplicates) %=percent of total exposure for all records (including duplicates)

Food, FF, N , Percent, Food Name --------, ---, -----, -------, -------------95000190, 212, 79, 32.48%, Asparagus-Cooked; Fresh or N/S; Boiled95000190, 242, 28, 13.54%, Asparagus-Cooked; Canned; Boiled13020570, 110, 63, 6.66%, Blueberry-Uncooked; Fresh or N/S; Cook Meth N/S13020570, 211, 46, 4.79%, Blueberry-Cooked; Fresh or N/S; Baked 4020850, 110, 109, 3.47%, Celery-Uncooked; Fresh or N/S; Cook Meth N/S95002350, 240, 43, 2.68%, Olive-Cooked; Canned; Cook Meth N/S12002300, 110, 32, 2.37%, Nectarine-Uncooked; Fresh or N/S; Cook Meth N/S 9010750, 110, 69, 2.35%, Cantaloupe-Uncooked; Fresh or N/S; Cook Meth N/S95000190, 222, 7, 2.16%, Asparagus-Cooked; Frozen; Boiled95003590, 110, 64, 2.04%, Strawberry-Uncooked; Fresh or N/S; Cook Meth N/S11000070, 110, 72, 1.81%, Apple, fruit with peel-Uncooked; Fresh or N/S; CookMeth N/S 5023890, 212, 19, 1.80%, Turnip, greens-Cooked; Fresh or N/S; Boiled 5021170, 212, 20, 1.56%, Collards-Cooked; Fresh or N/S; Boiled12002600, 110, 51, 1.49%, Peach-Uncooked; Fresh or N/S; Cook Meth N/S95001750, 110, 60, 1.36%, Grape-Uncooked; Fresh or N/S; Cook Meth N/S13013200, 120, 13, 1.27%, Raspberry-Uncooked; Frozen; Cook Meth N/S13013200, 240, 68, 1.21%, Raspberry-Cooked; Canned; Cook Meth N/S 9011870, 110, 24, 1.07%, Honeydew melon-Uncooked; Fresh or N/S; Cook MethN/S12002880, 110, 16, 0.94%, Plum, prune, juice-Uncooked; Fresh or N/S; CookMeth N/S95003590, 240, 61, 0.78%, Strawberry-Cooked; Canned; Cook Meth N/S13013200, 110, 26, 0.77%, Raspberry-Uncooked; Fresh or N/S; Cook Meth N/S 6010430, 212, 54, 0.69%, Bean, snap, succulent-Cooked; Fresh or N/S; Boiled 4023220, 240, 4, 0.57%, Rhubarb-Cooked; Canned; Cook Meth N/S 5022290, 212, 8, 0.54%, Mustard greens-Cooked; Fresh or N/S; Boiled 8002700, 110, 50, 0.51%, Pepper, bell-Uncooked; Fresh or N/S; Cook Meth N/S 4020850, 210, 26, 0.50%, Celery-Cooked; Fresh or N/S; Cook Meth N/S 8002700, 210, 25, 0.50%, Pepper, bell-Cooked; Fresh or N/S; Cook Meth N/S13010550, 240, 49, 0.46%, Blackberry-Cooked; Canned; Cook Meth N/S11002660, 110, 28, 0.46%, Pear-Uncooked; Fresh or N/S; Cook Meth N/S12000120, 240, 51, 0.46%, Apricot-Cooked; Canned; Cook Meth N/S 4023670, 212, 4, 0.45%, Swiss chard-Cooked; Fresh or N/S; Boiled12000900, 110, 10, 0.37%, Cherry-Uncooked; Fresh or N/S; Cook Meth N/S 4020850, 212, 46, 0.37%, Celery-Cooked; Fresh or N/S; Boiled12002600, 240, 38, 0.36%, Peach-Cooked; Canned; Cook Meth N/S95001790, 110, 50, 0.33%, Grape, wine and sherry-Uncooked; Fresh or N/S; CookMeth N/S12002850, 110, 17, 0.26%, Plum-Uncooked; Fresh or N/S; Cook Meth N/S12000130, 130, 6, 0.25%, Apricot, dried-Uncooked; Dried; Cook Meth N/S13020570, 120, 11, 0.23%, Blueberry-Uncooked; Frozen; Cook Meth N/S13010550, 211, 3, 0.21%, Blackberry-Cooked; Fresh or N/S; Baked 4023220, 211, 4, 0.21%, Rhubarb-Cooked; Fresh or N/S; Baked 4020860, 110, 3, 0.20%, Celery, juice-Uncooked; Fresh or N/S; Cook Meth N/S13010550, 110, 3, 0.17%, Blackberry-Uncooked; Fresh or N/S; Cook Meth N/S 6010430, 242, 13, 0.17%, Bean, snap, succulent-Cooked; Canned; Boiled 9021350, 110, 34, 0.16%, Cucumber-Uncooked; Fresh or N/S; Cook Meth N/S 5023890, 242, 2, 0.16%, Turnip, greens-Cooked; Canned; Boiled 5021170, 222, 1, 0.15%, Collards-Cooked; Frozen; Boiled95000190, 110, 1, 0.14%, Asparagus-Uncooked; Fresh or N/S; Cook Meth N/S11000110, 212, 14, 0.14%, Apple, sauce-Cooked; Fresh or N/S; Boiled95003600, 240, 21, 0.14%, Strawberry, juice-Cooked; Canned; Cook Meth N/S

296

11002660, 240, 8, 0.12%, Pear-Cooked; Canned; Cook Meth N/S10002400, 110, 27, 0.12%, Orange-Uncooked; Fresh or N/S; Cook Meth N/S 8002720, 210, 2, 0.12%, Pepper, nonbell-Cooked; Fresh or N/S; Cook Meth N/S95002350, 211, 7, 0.11%, Olive-Cooked; Fresh or N/S; Baked12000900, 211, 8, 0.11%, Cherry-Cooked; Fresh or N/S; Baked12002610, 130, 4, 0.11%, Peach, dried-Uncooked; Dried; Cook Meth N/S12002600, 120, 2, 0.10%, Peach-Uncooked; Frozen; Cook Meth N/S12000120, 110, 2, 0.08%, Apricot-Uncooked; Fresh or N/S; Cook Meth N/S10001810, 110, 15, 0.08%, Grapefruit, juice-Uncooked; Fresh or N/S; Cook MethN/S95001750, 240, 27, 0.08%, Grape-Cooked; Canned; Cook Meth N/S95003590, 211, 4, 0.08%, Strawberry-Cooked; Fresh or N/S; Baked13013210, 110, 2, 0.08%, Raspberry, juice-Uncooked; Fresh or N/S; Cook MethN/S12000130, 211, 5, 0.06%, Apricot, dried-Cooked; Fresh or N/S; Baked 5022290, 242, 1, 0.06%, Mustard greens-Cooked; Canned; Boiled12000140, 110, 1, 0.06%, Apricot, juice-Uncooked; Fresh or N/S; Cook MethN/S12002600, 211, 8, 0.06%, Peach-Cooked; Fresh or N/S; Baked11000070, 211, 2, 0.06%, Apple, fruit with peel-Cooked; Fresh or N/S; Baked 6010430, 210, 5, 0.06%, Bean, snap, succulent-Cooked; Fresh or N/S; CookMeth N/S 5021940, 212, 10, 0.06%, Kale-Cooked; Fresh or N/S; Boiled 6010430, 222, 3, 0.05%, Bean, snap, succulent-Cooked; Frozen; Boiled13020570, 213, 1, 0.05%, Blueberry-Cooked; Fresh or N/S; Fried10002000, 110, 9, 0.04%, Lemon, juice-Uncooked; Fresh or N/S; Cook Meth N/S95001760, 110, 6, 0.04%, Grape, juice-Uncooked; Fresh or N/S; Cook Meth N/S95003590, 120, 1, 0.04%, Strawberry-Uncooked; Frozen; Cook Meth N/S10001800, 110, 20, 0.04%, Grapefruit-Uncooked; Fresh or N/S; Cook Meth N/S10002410, 110, 21, 0.04%, Orange, juice-Uncooked; Fresh or N/S; Cook Meth N/S 8002340, 210, 2, 0.04%, Okra-Cooked; Fresh or N/S; Cook Meth N/S 8002720, 110, 2, 0.04%, Pepper, nonbell-Uncooked; Fresh or N/S; Cook MethN/S 8002700, 211, 7, 0.03%, Pepper, bell-Cooked; Fresh or N/S; Baked 8002720, 240, 4, 0.03%, Pepper, nonbell-Cooked; Canned; Cook Meth N/S13020570, 214, 1, 0.03%, Blueberry-Cooked; Fresh or N/S; Fried/baked95002350, 210, 3, 0.03%, Olive-Cooked; Fresh or N/S; Cook Meth N/S13020570, 230, 2, 0.03%, Blueberry-Cooked; Dried; Cook Meth N/S 4020850, 211, 2, 0.03%, Celery-Cooked; Fresh or N/S; Baked 4013550, 212, 7, 0.03%, Spinach-Cooked; Fresh or N/S; Boiled 8002700, 213, 6, 0.03%, Pepper, bell-Cooked; Fresh or N/S; Fried13020570, 210, 2, 0.03%, Blueberry-Cooked; Fresh or N/S; Cook Meth N/S11000080, 211, 4, 0.03%, Apple, peeled fruit-Cooked; Fresh or N/S; Baked13013200, 211, 6, 0.03%, Raspberry-Cooked; Fresh or N/S; Baked13010580, 120, 1, 0.03%, Boysenberry-Uncooked; Frozen; Cook Meth N/S 5020700, 210, 1, 0.03%, Cabbage, Chinese, bok choy-Cooked; Fresh or N/S;Cook Meth N/S11000100, 110, 11, 0.03%, Apple, juice-Uncooked; Fresh or N/S; Cook Meth N/S11002680, 240, 6, 0.02%, Pear, juice-Cooked; Canned; Cook Meth N/S95002810, 110, 6, 0.02%, Pineapple, juice-Uncooked; Fresh or N/S; Cook MethN/S 8001480, 214, 5, 0.02%, Eggplant-Cooked; Fresh or N/S; Fried/baked 4020850, 232, 3, 0.02%, Celery-Cooked; Dried; Boiled13021370, 130, 1, 0.02%, Currant, dried-Uncooked; Dried; Cook Meth N/S12000140, 240, 1, 0.02%, Apricot, juice-Cooked; Canned; Cook Meth N/S10002070, 110, 4, 0.02%, Lime, juice-Uncooked; Fresh or N/S; Cook Meth N/S12000900, 120, 1, 0.02%, Cherry-Uncooked; Frozen; Cook Meth N/S 6010430, 213, 3, 0.02%, Bean, snap, succulent-Cooked; Fresh or N/S; Fried13020570, 240, 4, 0.02%, Blueberry-Cooked; Canned; Cook Meth N/S 6010430, 215, 1, 0.01%, Bean, snap, succulent-Cooked; Fresh or N/S;Boiled/baked 8002700, 221, 2, 0.01%, Pepper, bell-Cooked; Frozen; Baked 8001480, 212, 4, 0.01%, Eggplant-Cooked; Fresh or N/S; Boiled 8002720, 213, 1, 0.01%, Pepper, nonbell-Cooked; Fresh or N/S; Fried12002870, 130, 2, 0.01%, Plum, prune, dried-Uncooked; Dried; Cook Meth N/S

297

8002700, 212, 6, 0.01%, Pepper, bell-Cooked; Fresh or N/S; Boiled12002860, 232, 3, 0.01%, Plum, prune, fresh-Cooked; Dried; Boiled 9021350, 240, 8, 0.01%, Cucumber-Cooked; Canned; Cook Meth N/S 8002700, 150, 3, 0.01%, Pepper, bell-Uncooked; Cured etc; Cook Meth N/S12000900, 240, 4, 0.01%, Cherry-Cooked; Canned; Cook Meth N/S10002410, 120, 8, 0.01%, Orange, juice-Uncooked; Frozen; Cook Meth N/S 4020850, 150, 1, 0.01%, Celery-Uncooked; Cured etc; Cook Meth N/S11000070, 213, 1, 0.01%, Apple, fruit with peel-Cooked; Fresh or N/S; Fried95001760, 240, 5, 0.01%, Grape, juice-Cooked; Canned; Cook Meth N/S95001780, 130, 5, 0.01%, Grape, raisin-Uncooked; Dried; Cook Meth N/S 6010430, 221, 2, 0.01%, Bean, snap, succulent-Cooked; Frozen; Baked 8002720, 150, 1, 0.01%, Pepper, nonbell-Uncooked; Cured etc; Cook Meth N/S 9013990, 110, 3, 0.01%, Watermelon-Uncooked; Fresh or N/S; Cook Meth N/S 6010430, 110, 1, 0.01%, Bean, snap, succulent-Uncooked; Fresh or N/S; CookMeth N/S 8002340, 150, 1, 0.01%, Okra-Uncooked; Cured etc; Cook Meth N/S 4020850, 242, 1, 0.01%, Celery-Cooked; Canned; Boiled 1033000, 212, 4, 0.01%, Potato, tuber, w/o peel-Cooked; Fresh or N/S;Boiled10001810, 240, 2, 0.01%, Grapefruit, juice-Cooked; Canned; Cook Meth N/S10001070, 110, 1, 0.01%, Citrus hybrids-Uncooked; Fresh or N/S; Cook MethN/S11000090, 211, 2, 0.01%, Apple, dried-Cooked; Fresh or N/S; Baked11000090, 130, 2, 0.01%, Apple, dried-Uncooked; Dried; Cook Meth N/S95002790, 110, 3, 0.01%, Pineapple-Uncooked; Fresh or N/S; Cook Meth N/S11002670, 130, 2, 0.01%, Pear, dried-Uncooked; Dried; Cook Meth N/S25002930, 213, 1, 0.00%, Pork, fat-Cooked; Fresh or N/S; Fried 8001480, 211, 1, 0.00%, Eggplant-Cooked; Fresh or N/S; Baked11000080, 221, 1, 0.00%, Apple, peeled fruit-Cooked; Frozen; Baked 8002720, 221, 1, 0.00%, Pepper, nonbell-Cooked; Frozen; Baked95002790, 240, 3, 0.00%, Pineapple-Cooked; Canned; Cook Meth N/S 1032990, 212, 3, 0.00%, Potato, tuber, w/peel-Cooked; Fresh or N/S; Boiled10002000, 211, 1, 0.00%, Lemon, juice-Cooked; Fresh or N/S; Baked10003700, 110, 1, 0.00%, Tangerine, juice-Uncooked; Fresh or N/S; Cook MethN/S 4020850, 240, 2, 0.00%, Celery-Cooked; Canned; Cook Meth N/S11000080, 232, 1, 0.00%, Apple, peeled fruit-Cooked; Dried; Boiled11002680, 110, 1, 0.00%, Pear, juice-Uncooked; Fresh or N/S; Cook Meth N/S 8002340, 212, 1, 0.00%, Okra-Cooked; Fresh or N/S; Boiled 4013550, 211, 1, 0.00%, Spinach-Cooked; Fresh or N/S; Baked10003690, 110, 1, 0.00%, Tangerine-Uncooked; Fresh or N/S; Cook Meth N/S95001750, 120, 1, 0.00%, Grape-Uncooked; Frozen; Cook Meth N/S 4020850, 215, 1, 0.00%, Celery-Cooked; Fresh or N/S; Boiled/baked95002810, 120, 1, 0.00%, Pineapple, juice-Uncooked; Frozen; Cook Meth N/S 8002730, 212, 1, 0.00%, Pepper, nonbell, dried-Cooked; Fresh or N/S; Boiled 4013550, 110, 1, 0.00%, Spinach-Uncooked; Fresh or N/S; Cook Meth N/S 8002700, 240, 1, 0.00%, Pepper, bell-Cooked; Canned; Cook Meth N/S 1033660, 210, 1, 0.00%, Sweet potato-Cooked; Fresh or N/S; Cook Meth N/S 8003790, 240, 1, 0.00%, Tomato, juice-Cooked; Canned; Cook Meth N/S11000100, 240, 1, 0.00%, Apple, juice-Cooked; Canned; Cook Meth N/S 9021350, 150, 1, 0.00%, Cucumber-Uncooked; Cured etc; Cook Meth N/S10002000, 240, 1, 0.00%, Lemon, juice-Cooked; Canned; Cook Meth N/S15003250, 232, 1, 0.00%, Rice, flour-Cooked; Dried; Boiled

298

Females 13-49 yrsLow percentile for CEC records: 95 Exposure (mg/day) = 0.004568High percentile for CEC records: 100 Exposure (mg/day) = 0.069531Number of actual records in this interval: 286

Critical foods/foodforms for this population (as derived from these records): N=number of appearances in all records (including duplicates) %=percent of total exposure for all records (including duplicates)

Food, FF, N , Percent, Food Name --------, ---, -----, -------, -------------95000190, 212, 15, 15.71%, Asparagus-Cooked; Fresh or N/S; Boiled13020570, 110, 46, 10.84%, Blueberry-Uncooked; Fresh or N/S; Cook Meth N/S95002350, 240, 51, 9.23%, Olive-Cooked; Canned; Cook Meth N/S95000190, 242, 8, 6.78%, Asparagus-Cooked; Canned; Boiled13020570, 211, 35, 4.67%, Blueberry-Cooked; Fresh or N/S; Baked 4020850, 110, 61, 4.23%, Celery-Uncooked; Fresh or N/S; Cook Meth N/S12002300, 110, 33, 4.15%, Nectarine-Uncooked; Fresh or N/S; Cook Meth N/S95003590, 110, 46, 3.81%, Strawberry-Uncooked; Fresh or N/S; Cook Meth N/S11000070, 110, 60, 3.17%, Apple, fruit with peel-Uncooked; Fresh or N/S; CookMeth N/S 9010750, 110, 35, 2.76%, Cantaloupe-Uncooked; Fresh or N/S; Cook Meth N/S95000190, 222, 4, 2.38%, Asparagus-Cooked; Frozen; Boiled95001750, 110, 39, 2.05%, Grape-Uncooked; Fresh or N/S; Cook Meth N/S13013200, 240, 33, 1.93%, Raspberry-Cooked; Canned; Cook Meth N/S 5021170, 212, 10, 1.82%, Collards-Cooked; Fresh or N/S; Boiled13020570, 120, 8, 1.55%, Blueberry-Uncooked; Frozen; Cook Meth N/S13013200, 110, 25, 1.25%, Raspberry-Uncooked; Fresh or N/S; Cook Meth N/S95003590, 240, 32, 1.15%, Strawberry-Cooked; Canned; Cook Meth N/S12002600, 110, 17, 0.92%, Peach-Uncooked; Fresh or N/S; Cook Meth N/S 5023890, 212, 7, 0.82%, Turnip, greens-Cooked; Fresh or N/S; Boiled 4020850, 212, 37, 0.81%, Celery-Cooked; Fresh or N/S; Boiled12000130, 130, 4, 0.76%, Apricot, dried-Uncooked; Dried; Cook Meth N/S 8002700, 210, 14, 0.73%, Pepper, bell-Cooked; Fresh or N/S; Cook Meth N/S13020570, 214, 5, 0.73%, Blueberry-Cooked; Fresh or N/S; Fried/baked 8002700, 110, 25, 0.70%, Pepper, bell-Uncooked; Fresh or N/S; Cook Meth N/S13020570, 240, 7, 0.69%, Blueberry-Cooked; Canned; Cook Meth N/S13010550, 211, 2, 0.65%, Blackberry-Cooked; Fresh or N/S; Baked12000120, 240, 30, 0.63%, Apricot-Cooked; Canned; Cook Meth N/S13020570, 213, 5, 0.59%, Blueberry-Cooked; Fresh or N/S; Fried 9011870, 110, 14, 0.57%, Honeydew melon-Uncooked; Fresh or N/S; Cook MethN/S13010550, 240, 32, 0.56%, Blackberry-Cooked; Canned; Cook Meth N/S 4023220, 240, 1, 0.50%, Rhubarb-Cooked; Canned; Cook Meth N/S95000190, 110, 1, 0.47%, Asparagus-Uncooked; Fresh or N/S; Cook Meth N/S 4020850, 210, 11, 0.46%, Celery-Cooked; Fresh or N/S; Cook Meth N/S12002880, 110, 4, 0.42%, Plum, prune, juice-Uncooked; Fresh or N/S; CookMeth N/S11002660, 110, 9, 0.41%, Pear-Uncooked; Fresh or N/S; Cook Meth N/S 5023890, 222, 1, 0.40%, Turnip, greens-Cooked; Frozen; Boiled 5021170, 242, 2, 0.38%, Collards-Cooked; Canned; Boiled13013200, 211, 6, 0.37%, Raspberry-Cooked; Fresh or N/S; Baked11000070, 211, 2, 0.36%, Apple, fruit with peel-Cooked; Fresh or N/S; Baked12002850, 110, 8, 0.35%, Plum-Uncooked; Fresh or N/S; Cook Meth N/S12002600, 240, 27, 0.35%, Peach-Cooked; Canned; Cook Meth N/S13010550, 110, 5, 0.34%, Blackberry-Uncooked; Fresh or N/S; Cook Meth N/S 5022290, 212, 4, 0.33%, Mustard greens-Cooked; Fresh or N/S; Boiled 6010430, 242, 6, 0.32%, Bean, snap, succulent-Cooked; Canned; Boiled13010550, 120, 2, 0.30%, Blackberry-Uncooked; Frozen; Cook Meth N/S 4020850, 242, 7, 0.30%, Celery-Cooked; Canned; Boiled 5021170, 222, 2, 0.29%, Collards-Cooked; Frozen; Boiled11000080, 211, 6, 0.29%, Apple, peeled fruit-Cooked; Fresh or N/S; Baked 6010430, 212, 18, 0.29%, Bean, snap, succulent-Cooked; Fresh or N/S; Boiled

299

95003600, 110, 3, 0.27%, Strawberry, juice-Uncooked; Fresh or N/S; Cook MethN/S95003600, 240, 12, 0.23%, Strawberry, juice-Cooked; Canned; Cook Meth N/S95001790, 110, 15, 0.22%, Grape, wine and sherry-Uncooked; Fresh or N/S; CookMeth N/S13013210, 110, 4, 0.22%, Raspberry, juice-Uncooked; Fresh or N/S; Cook MethN/S95002350, 211, 7, 0.21%, Olive-Cooked; Fresh or N/S; Baked 8002720, 110, 5, 0.17%, Pepper, nonbell-Uncooked; Fresh or N/S; Cook MethN/S 5020700, 150, 3, 0.17%, Cabbage, Chinese, bok choy-Uncooked; Cured etc;Cook Meth N/S10002400, 110, 19, 0.16%, Orange-Uncooked; Fresh or N/S; Cook Meth N/S 5022290, 242, 1, 0.14%, Mustard greens-Cooked; Canned; Boiled 9021350, 110, 22, 0.14%, Cucumber-Uncooked; Fresh or N/S; Cook Meth N/S 4023220, 211, 1, 0.12%, Rhubarb-Cooked; Fresh or N/S; Baked12002600, 211, 4, 0.12%, Peach-Cooked; Fresh or N/S; Baked12000140, 240, 3, 0.11%, Apricot, juice-Cooked; Canned; Cook Meth N/S10002410, 110, 27, 0.11%, Orange, juice-Uncooked; Fresh or N/S; Cook Meth N/S95002350, 212, 1, 0.11%, Olive-Cooked; Fresh or N/S; Boiled95001760, 110, 8, 0.11%, Grape, juice-Uncooked; Fresh or N/S; Cook Meth N/S11000110, 212, 5, 0.11%, Apple, sauce-Cooked; Fresh or N/S; Boiled13010580, 110, 3, 0.10%, Boysenberry-Uncooked; Fresh or N/S; Cook Meth N/S10002000, 110, 19, 0.09%, Lemon, juice-Uncooked; Fresh or N/S; Cook Meth N/S95003590, 120, 1, 0.09%, Strawberry-Uncooked; Frozen; Cook Meth N/S95001750, 240, 17, 0.08%, Grape-Cooked; Canned; Cook Meth N/S 9021350, 240, 14, 0.08%, Cucumber-Cooked; Canned; Cook Meth N/S95003590, 211, 4, 0.08%, Strawberry-Cooked; Fresh or N/S; Baked 6010430, 213, 4, 0.07%, Bean, snap, succulent-Cooked; Fresh or N/S; Fried 6010430, 222, 3, 0.07%, Bean, snap, succulent-Cooked; Frozen; Boiled12000120, 110, 1, 0.07%, Apricot-Uncooked; Fresh or N/S; Cook Meth N/S11000100, 110, 11, 0.06%, Apple, juice-Uncooked; Fresh or N/S; Cook Meth N/S95003600, 210, 5, 0.06%, Strawberry, juice-Cooked; Fresh or N/S; Cook MethN/S 8002700, 213, 4, 0.06%, Pepper, bell-Cooked; Fresh or N/S; Fried12000120, 211, 1, 0.06%, Apricot-Cooked; Fresh or N/S; Baked12000900, 110, 3, 0.06%, Cherry-Uncooked; Fresh or N/S; Cook Meth N/S13020570, 210, 2, 0.06%, Blueberry-Cooked; Fresh or N/S; Cook Meth N/S12002620, 110, 1, 0.06%, Peach, juice-Uncooked; Fresh or N/S; Cook Meth N/S12000910, 210, 5, 0.06%, Cherry, juice-Cooked; Fresh or N/S; Cook Meth N/S95001750, 210, 5, 0.05%, Grape-Cooked; Fresh or N/S; Cook Meth N/S13013210, 240, 3, 0.05%, Raspberry, juice-Cooked; Canned; Cook Meth N/S 4020850, 215, 4, 0.05%, Celery-Cooked; Fresh or N/S; Boiled/baked11002660, 210, 5, 0.05%, Pear-Cooked; Fresh or N/S; Cook Meth N/S 8002700, 150, 5, 0.05%, Pepper, bell-Uncooked; Cured etc; Cook Meth N/S 5020700, 210, 4, 0.05%, Cabbage, Chinese, bok choy-Cooked; Fresh or N/S;Cook Meth N/S10002410, 120, 10, 0.04%, Orange, juice-Uncooked; Frozen; Cook Meth N/S 4020850, 211, 3, 0.04%, Celery-Cooked; Fresh or N/S; Baked 8002700, 211, 5, 0.04%, Pepper, bell-Cooked; Fresh or N/S; Baked10001800, 110, 7, 0.04%, Grapefruit-Uncooked; Fresh or N/S; Cook Meth N/S10001810, 110, 3, 0.04%, Grapefruit, juice-Uncooked; Fresh or N/S; Cook MethN/S95002810, 110, 2, 0.04%, Pineapple, juice-Uncooked; Fresh or N/S; Cook MethN/S 8002720, 210, 4, 0.03%, Pepper, nonbell-Cooked; Fresh or N/S; Cook Meth N/S95001780, 130, 3, 0.03%, Grape, raisin-Uncooked; Dried; Cook Meth N/S13021360, 110, 1, 0.03%, Currant-Uncooked; Fresh or N/S; Cook Meth N/S 5021940, 212, 3, 0.03%, Kale-Cooked; Fresh or N/S; Boiled 8002720, 150, 3, 0.03%, Pepper, nonbell-Uncooked; Cured etc; Cook Meth N/S12002600, 120, 2, 0.02%, Peach-Uncooked; Frozen; Cook Meth N/S12002860, 232, 2, 0.02%, Plum, prune, fresh-Cooked; Dried; Boiled 5020700, 110, 1, 0.02%, Cabbage, Chinese, bok choy-Uncooked; Fresh or N/S;Cook Meth N/S11002680, 110, 3, 0.02%, Pear, juice-Uncooked; Fresh or N/S; Cook Meth N/S

300

10002070, 110, 4, 0.02%, Lime, juice-Uncooked; Fresh or N/S; Cook Meth N/S12000900, 210, 1, 0.02%, Cherry-Cooked; Fresh or N/S; Cook Meth N/S95001760, 240, 5, 0.02%, Grape, juice-Cooked; Canned; Cook Meth N/S13013200, 120, 4, 0.02%, Raspberry-Uncooked; Frozen; Cook Meth N/S 8002720, 240, 2, 0.02%, Pepper, nonbell-Cooked; Canned; Cook Meth N/S95002790, 240, 5, 0.02%, Pineapple-Cooked; Canned; Cook Meth N/S11002660, 240, 2, 0.02%, Pear-Cooked; Canned; Cook Meth N/S12000900, 211, 2, 0.02%, Cherry-Cooked; Fresh or N/S; Baked12002620, 240, 1, 0.01%, Peach, juice-Cooked; Canned; Cook Meth N/S 1033000, 212, 3, 0.01%, Potato, tuber, w/o peel-Cooked; Fresh or N/S;Boiled11002680, 240, 3, 0.01%, Pear, juice-Cooked; Canned; Cook Meth N/S12000900, 240, 2, 0.01%, Cherry-Cooked; Canned; Cook Meth N/S 6010430, 240, 2, 0.01%, Bean, snap, succulent-Cooked; Canned; Cook Meth N/S12002860, 211, 1, 0.01%, Plum, prune, fresh-Cooked; Fresh or N/S; Baked 8002700, 215, 3, 0.01%, Pepper, bell-Cooked; Fresh or N/S; Boiled/baked10001810, 120, 1, 0.01%, Grapefruit, juice-Uncooked; Frozen; Cook Meth N/S12000140, 110, 2, 0.01%, Apricot, juice-Uncooked; Fresh or N/S; Cook MethN/S10002000, 240, 2, 0.01%, Lemon, juice-Cooked; Canned; Cook Meth N/S10002000, 210, 3, 0.01%, Lemon, juice-Cooked; Fresh or N/S; Cook Meth N/S11000080, 221, 1, 0.01%, Apple, peeled fruit-Cooked; Frozen; Baked10001810, 240, 1, 0.01%, Grapefruit, juice-Cooked; Canned; Cook Meth N/S 4013550, 212, 3, 0.01%, Spinach-Cooked; Fresh or N/S; Boiled10001990, 110, 2, 0.01%, Lemon-Uncooked; Fresh or N/S; Cook Meth N/S13010580, 240, 2, 0.01%, Boysenberry-Cooked; Canned; Cook Meth N/S10003700, 110, 2, 0.01%, Tangerine, juice-Uncooked; Fresh or N/S; Cook MethN/S10003690, 110, 1, 0.01%, Tangerine-Uncooked; Fresh or N/S; Cook Meth N/S 8002700, 212, 1, 0.01%, Pepper, bell-Cooked; Fresh or N/S; Boiled 4020850, 232, 1, 0.01%, Celery-Cooked; Dried; Boiled95003600, 211, 1, 0.01%, Strawberry, juice-Cooked; Fresh or N/S; Baked95000730, 110, 1, 0.00%, Cactus-Uncooked; Fresh or N/S; Cook Meth N/S95002790, 110, 2, 0.00%, Pineapple-Uncooked; Fresh or N/S; Cook Meth N/S 4013550, 110, 1, 0.00%, Spinach-Uncooked; Fresh or N/S; Cook Meth N/S13010580, 120, 1, 0.00%, Boysenberry-Uncooked; Frozen; Cook Meth N/S13013210, 120, 1, 0.00%, Raspberry, juice-Uncooked; Frozen; Cook Meth N/S11000090, 211, 1, 0.00%, Apple, dried-Cooked; Fresh or N/S; Baked 8003770, 210, 1, 0.00%, Tomato, puree-Cooked; Fresh or N/S; Cook Meth N/S 8002700, 221, 1, 0.00%, Pepper, bell-Cooked; Frozen; Baked 9021350, 212, 1, 0.00%, Cucumber-Cooked; Fresh or N/S; Boiled12000910, 110, 1, 0.00%, Cherry, juice-Uncooked; Fresh or N/S; Cook Meth N/S15003240, 232, 1, 0.00%, Rice, brown-Cooked; Dried; Boiled12000140, 120, 1, 0.00%, Apricot, juice-Uncooked; Frozen; Cook Meth N/S 8001480, 213, 1, 0.00%, Eggplant-Cooked; Fresh or N/S; Fried95002790, 210, 1, 0.00%, Pineapple-Cooked; Fresh or N/S; Cook Meth N/S10003700, 240, 1, 0.00%, Tangerine, juice-Cooked; Canned; Cook Meth N/S10002070, 120, 1, 0.00%, Lime, juice-Uncooked; Frozen; Cook Meth N/S95001760, 210, 1, 0.00%, Grape, juice-Cooked; Fresh or N/S; Cook Meth N/S 1033660, 215, 1, 0.00%, Sweet potato-Cooked; Fresh or N/S; Boiled/baked 9013990, 110, 1, 0.00%, Watermelon-Uncooked; Fresh or N/S; Cook Meth N/S10002070, 240, 1, 0.00%, Lime, juice-Cooked; Canned; Cook Meth N/S15001240, 240, 1, 0.00%, Corn, field, syrup-Cooked; Canned; Cook Meth N/S11000100, 240, 1, 0.00%, Apple, juice-Cooked; Canned; Cook Meth N/S10003700, 120, 1, 0.00%, Tangerine, juice-Uncooked; Frozen; Cook Meth N/S

301

Custom demographics 1: Adults 16-70 yrLow percentile for CEC records: 95 Exposure (mg/day) = 0.004546High percentile for CEC records: 100 Exposure (mg/day) = 0.096606Number of actual records in this interval: 860

Critical foods/foodforms for this population (as derived from these records): N=number of appearances in all records (including duplicates) %=percent of total exposure for all records (including duplicates)

Food, FF, N , Percent, Food Name --------, ---, -----, -------, -------------95000190, 212, 85, 21.83%, Asparagus-Cooked; Fresh or N/S; Boiled95000190, 242, 35, 12.38%, Asparagus-Cooked; Canned; Boiled13020570, 110, 119, 7.13%, Blueberry-Uncooked; Fresh or N/S; Cook Meth N/S95002350, 240, 131, 6.39%, Olive-Cooked; Canned; Cook Meth N/S13020570, 211, 104, 5.90%, Blueberry-Cooked; Fresh or N/S; Baked 4020850, 110, 208, 3.98%, Celery-Uncooked; Fresh or N/S; Cook Meth N/S12002300, 110, 81, 3.48%, Nectarine-Uncooked; Fresh or N/S; Cook Meth N/S 9010750, 110, 135, 2.90%, Cantaloupe-Uncooked; Fresh or N/S; Cook Meth N/S11000070, 110, 176, 2.54%, Apple, fruit with peel-Uncooked; Fresh or N/S; CookMeth N/S95003590, 110, 121, 2.50%, Strawberry-Uncooked; Fresh or N/S; Cook Meth N/S95000190, 222, 12, 2.09%, Asparagus-Cooked; Frozen; Boiled95001750, 110, 111, 1.77%, Grape-Uncooked; Fresh or N/S; Cook Meth N/S 5021170, 212, 32, 1.60%, Collards-Cooked; Fresh or N/S; Boiled13013200, 240, 102, 1.55%, Raspberry-Cooked; Canned; Cook Meth N/S 5023890, 212, 31, 1.55%, Turnip, greens-Cooked; Fresh or N/S; Boiled12002600, 110, 69, 1.25%, Peach-Uncooked; Fresh or N/S; Cook Meth N/S 9011870, 110, 50, 1.06%, Honeydew melon-Uncooked; Fresh or N/S; Cook MethN/S95003590, 240, 97, 0.99%, Strawberry-Cooked; Canned; Cook Meth N/S13013200, 110, 53, 0.94%, Raspberry-Uncooked; Fresh or N/S; Cook Meth N/S 4020850, 210, 50, 0.85%, Celery-Cooked; Fresh or N/S; Cook Meth N/S13013200, 120, 21, 0.82%, Raspberry-Uncooked; Frozen; Cook Meth N/S13020570, 120, 22, 0.68%, Blueberry-Uncooked; Frozen; Cook Meth N/S 8002700, 110, 103, 0.66%, Pepper, bell-Uncooked; Fresh or N/S; Cook Meth N/S 4020850, 212, 98, 0.58%, Celery-Cooked; Fresh or N/S; Boiled 8002700, 210, 46, 0.56%, Pepper, bell-Cooked; Fresh or N/S; Cook Meth N/S13010550, 240, 88, 0.56%, Blackberry-Cooked; Canned; Cook Meth N/S 5022290, 212, 14, 0.49%, Mustard greens-Cooked; Fresh or N/S; Boiled12000130, 130, 13, 0.48%, Apricot, dried-Uncooked; Dried; Cook Meth N/S12000120, 240, 85, 0.47%, Apricot-Cooked; Canned; Cook Meth N/S 6010430, 212, 61, 0.41%, Bean, snap, succulent-Cooked; Fresh or N/S; Boiled12002880, 110, 12, 0.37%, Plum, prune, juice-Uncooked; Fresh or N/S; CookMeth N/S11002660, 110, 28, 0.35%, Pear-Uncooked; Fresh or N/S; Cook Meth N/S13010550, 211, 5, 0.33%, Blackberry-Cooked; Fresh or N/S; Baked13013210, 110, 9, 0.32%, Raspberry, juice-Uncooked; Fresh or N/S; Cook MethN/S95001790, 110, 80, 0.32%, Grape, wine and sherry-Uncooked; Fresh or N/S; CookMeth N/S13020570, 213, 9, 0.31%, Blueberry-Cooked; Fresh or N/S; Fried12002600, 240, 79, 0.31%, Peach-Cooked; Canned; Cook Meth N/S95002350, 211, 25, 0.29%, Olive-Cooked; Fresh or N/S; Baked12000900, 110, 15, 0.29%, Cherry-Uncooked; Fresh or N/S; Cook Meth N/S12002850, 110, 33, 0.29%, Plum-Uncooked; Fresh or N/S; Cook Meth N/S 4023220, 211, 7, 0.29%, Rhubarb-Cooked; Fresh or N/S; Baked 4023670, 212, 5, 0.29%, Swiss chard-Cooked; Fresh or N/S; Boiled13020570, 240, 9, 0.27%, Blueberry-Cooked; Canned; Cook Meth N/S 4023220, 240, 2, 0.24%, Rhubarb-Cooked; Canned; Cook Meth N/S95000190, 110, 2, 0.24%, Asparagus-Uncooked; Fresh or N/S; Cook Meth N/S95003600, 240, 43, 0.22%, Strawberry, juice-Cooked; Canned; Cook Meth N/S 6010430, 242, 21, 0.22%, Bean, snap, succulent-Cooked; Canned; Boiled 5021170, 222, 3, 0.19%, Collards-Cooked; Frozen; Boiled

302

10002400, 110, 58, 0.18%, Orange-Uncooked; Fresh or N/S; Cook Meth N/S 9021350, 110, 66, 0.18%, Cucumber-Uncooked; Fresh or N/S; Cook Meth N/S13010550, 120, 3, 0.17%, Blackberry-Uncooked; Frozen; Cook Meth N/S 4020850, 232, 9, 0.15%, Celery-Cooked; Dried; Boiled95003590, 211, 10, 0.14%, Strawberry-Cooked; Fresh or N/S; Baked13013200, 211, 13, 0.13%, Raspberry-Cooked; Fresh or N/S; Baked13010550, 110, 5, 0.13%, Blackberry-Uncooked; Fresh or N/S; Cook Meth N/S11000070, 211, 3, 0.13%, Apple, fruit with peel-Cooked; Fresh or N/S; Baked 5023890, 222, 1, 0.12%, Turnip, greens-Cooked; Frozen; Boiled 8002720, 110, 10, 0.12%, Pepper, nonbell-Uncooked; Fresh or N/S; Cook MethN/S11000080, 211, 12, 0.11%, Apple, peeled fruit-Cooked; Fresh or N/S; Baked 5020700, 150, 6, 0.11%, Cabbage, Chinese, bok choy-Uncooked; Cured etc;Cook Meth N/S95003600, 110, 5, 0.11%, Strawberry, juice-Uncooked; Fresh or N/S; Cook MethN/S11000110, 212, 16, 0.10%, Apple, sauce-Cooked; Fresh or N/S; Boiled95001750, 240, 59, 0.10%, Grape-Cooked; Canned; Cook Meth N/S 4020860, 110, 2, 0.10%, Celery, juice-Uncooked; Fresh or N/S; Cook Meth N/S 5023890, 242, 2, 0.10%, Turnip, greens-Cooked; Canned; Boiled10002410, 110, 68, 0.09%, Orange, juice-Uncooked; Fresh or N/S; Cook Meth N/S13020570, 214, 4, 0.09%, Blueberry-Cooked; Fresh or N/S; Fried/baked 4020850, 242, 9, 0.09%, Celery-Cooked; Canned; Boiled12002600, 120, 5, 0.09%, Peach-Uncooked; Frozen; Cook Meth N/S 5022290, 242, 2, 0.08%, Mustard greens-Cooked; Canned; Boiled12002600, 211, 12, 0.08%, Peach-Cooked; Fresh or N/S; Baked 5020700, 210, 10, 0.08%, Cabbage, Chinese, bok choy-Cooked; Fresh or N/S;Cook Meth N/S 8002340, 210, 5, 0.08%, Okra-Cooked; Fresh or N/S; Cook Meth N/S 6010430, 222, 9, 0.08%, Bean, snap, succulent-Cooked; Frozen; Boiled10002000, 110, 39, 0.07%, Lemon, juice-Uncooked; Fresh or N/S; Cook Meth N/S95001760, 110, 14, 0.07%, Grape, juice-Uncooked; Fresh or N/S; Cook Meth N/S10001810, 110, 21, 0.07%, Grapefruit, juice-Uncooked; Fresh or N/S; Cook MethN/S12002610, 130, 4, 0.07%, Peach, dried-Uncooked; Dried; Cook Meth N/S11000100, 110, 37, 0.07%, Apple, juice-Uncooked; Fresh or N/S; Cook Meth N/S12000900, 211, 11, 0.07%, Cherry-Cooked; Fresh or N/S; Baked12000140, 240, 4, 0.06%, Apricot, juice-Cooked; Canned; Cook Meth N/S11002660, 240, 10, 0.05%, Pear-Cooked; Canned; Cook Meth N/S12000130, 211, 8, 0.05%, Apricot, dried-Cooked; Fresh or N/S; Baked 8002720, 210, 8, 0.05%, Pepper, nonbell-Cooked; Fresh or N/S; Cook Meth N/S 8002700, 211, 23, 0.05%, Pepper, bell-Cooked; Fresh or N/S; Baked 5021170, 242, 1, 0.05%, Collards-Cooked; Canned; Boiled13020570, 210, 6, 0.05%, Blueberry-Cooked; Fresh or N/S; Cook Meth N/S12000120, 110, 3, 0.05%, Apricot-Uncooked; Fresh or N/S; Cook Meth N/S95003590, 120, 4, 0.05%, Strawberry-Uncooked; Frozen; Cook Meth N/S 4020850, 211, 6, 0.05%, Celery-Cooked; Fresh or N/S; Baked 8002720, 240, 7, 0.04%, Pepper, nonbell-Cooked; Canned; Cook Meth N/S 5021940, 212, 12, 0.04%, Kale-Cooked; Fresh or N/S; Boiled 9021350, 240, 29, 0.04%, Cucumber-Cooked; Canned; Cook Meth N/S13010580, 120, 3, 0.04%, Boysenberry-Uncooked; Frozen; Cook Meth N/S13010560, 110, 1, 0.04%, Blackberry, juice-Uncooked; Fresh or N/S; Cook MethN/S 5022290, 222, 1, 0.04%, Mustard greens-Cooked; Frozen; Boiled 8002700, 150, 11, 0.04%, Pepper, bell-Uncooked; Cured etc; Cook Meth N/S 8002700, 213, 10, 0.03%, Pepper, bell-Cooked; Fresh or N/S; Fried 6010430, 210, 4, 0.03%, Bean, snap, succulent-Cooked; Fresh or N/S; CookMeth N/S95002350, 212, 1, 0.03%, Olive-Cooked; Fresh or N/S; Boiled12002620, 240, 2, 0.03%, Peach, juice-Cooked; Canned; Cook Meth N/S 8002700, 212, 10, 0.03%, Pepper, bell-Cooked; Fresh or N/S; Boiled12000900, 120, 2, 0.03%, Cherry-Uncooked; Frozen; Cook Meth N/S10001800, 110, 20, 0.03%, Grapefruit-Uncooked; Fresh or N/S; Cook Meth N/S13010580, 110, 2, 0.03%, Boysenberry-Uncooked; Fresh or N/S; Cook Meth N/S 6010430, 213, 6, 0.03%, Bean, snap, succulent-Cooked; Fresh or N/S; Fried

303

10002410, 120, 21, 0.02%, Orange, juice-Uncooked; Frozen; Cook Meth N/S10002070, 110, 8, 0.02%, Lime, juice-Uncooked; Fresh or N/S; Cook Meth N/S95001760, 240, 15, 0.02%, Grape, juice-Cooked; Canned; Cook Meth N/S 4020850, 215, 6, 0.02%, Celery-Cooked; Fresh or N/S; Boiled/baked 8002720, 213, 2, 0.02%, Pepper, nonbell-Cooked; Fresh or N/S; Fried11002680, 240, 8, 0.02%, Pear, juice-Cooked; Canned; Cook Meth N/S95002810, 110, 5, 0.02%, Pineapple, juice-Uncooked; Fresh or N/S; Cook MethN/S12000120, 211, 1, 0.02%, Apricot-Cooked; Fresh or N/S; Baked12002620, 110, 1, 0.02%, Peach, juice-Uncooked; Fresh or N/S; Cook Meth N/S95001780, 130, 9, 0.02%, Grape, raisin-Uncooked; Dried; Cook Meth N/S 8001480, 214, 6, 0.02%, Eggplant-Cooked; Fresh or N/S; Fried/baked95003600, 210, 4, 0.02%, Strawberry, juice-Cooked; Fresh or N/S; Cook MethN/S13021360, 110, 2, 0.01%, Currant-Uncooked; Fresh or N/S; Cook Meth N/S13013210, 240, 2, 0.01%, Raspberry, juice-Cooked; Canned; Cook Meth N/S 4013550, 212, 9, 0.01%, Spinach-Cooked; Fresh or N/S; Boiled12000910, 210, 4, 0.01%, Cherry, juice-Cooked; Fresh or N/S; Cook Meth N/S 8001480, 212, 6, 0.01%, Eggplant-Cooked; Fresh or N/S; Boiled13021370, 130, 1, 0.01%, Currant, dried-Uncooked; Dried; Cook Meth N/S 8002720, 150, 7, 0.01%, Pepper, nonbell-Uncooked; Cured etc; Cook Meth N/S95001750, 210, 4, 0.01%, Grape-Cooked; Fresh or N/S; Cook Meth N/S12000900, 240, 7, 0.01%, Cherry-Cooked; Canned; Cook Meth N/S11002660, 210, 4, 0.01%, Pear-Cooked; Fresh or N/S; Cook Meth N/S13020570, 230, 1, 0.01%, Blueberry-Cooked; Dried; Cook Meth N/S11000080, 221, 3, 0.01%, Apple, peeled fruit-Cooked; Frozen; Baked 8002700, 221, 3, 0.01%, Pepper, bell-Cooked; Frozen; Baked95002790, 240, 10, 0.01%, Pineapple-Cooked; Canned; Cook Meth N/S 6010430, 221, 3, 0.01%, Bean, snap, succulent-Cooked; Frozen; Baked12002870, 130, 2, 0.01%, Plum, prune, dried-Uncooked; Dried; Cook Meth N/S 1033000, 212, 9, 0.01%, Potato, tuber, w/o peel-Cooked; Fresh or N/S;Boiled11002680, 110, 3, 0.01%, Pear, juice-Uncooked; Fresh or N/S; Cook Meth N/S12002860, 232, 2, 0.01%, Plum, prune, fresh-Cooked; Dried; Boiled 5020700, 110, 1, 0.01%, Cabbage, Chinese, bok choy-Uncooked; Fresh or N/S;Cook Meth N/S12002860, 211, 2, 0.01%, Plum, prune, fresh-Cooked; Fresh or N/S; Baked 4020850, 150, 1, 0.01%, Celery-Uncooked; Cured etc; Cook Meth N/S95002350, 210, 1, 0.01%, Olive-Cooked; Fresh or N/S; Cook Meth N/S12000900, 210, 1, 0.01%, Cherry-Cooked; Fresh or N/S; Cook Meth N/S11000090, 211, 5, 0.01%, Apple, dried-Cooked; Fresh or N/S; Baked10001810, 240, 3, 0.01%, Grapefruit, juice-Cooked; Canned; Cook Meth N/S95002790, 110, 5, 0.01%, Pineapple-Uncooked; Fresh or N/S; Cook Meth N/S 4020850, 240, 3, 0.01%, Celery-Cooked; Canned; Cook Meth N/S 1032990, 212, 7, 0.01%, Potato, tuber, w/peel-Cooked; Fresh or N/S; Boiled10003690, 110, 3, 0.00%, Tangerine-Uncooked; Fresh or N/S; Cook Meth N/S 9020210, 212, 1, 0.00%, Balsam pear-Cooked; Fresh or N/S; Boiled10002000, 240, 3, 0.00%, Lemon, juice-Cooked; Canned; Cook Meth N/S 8002340, 150, 1, 0.00%, Okra-Uncooked; Cured etc; Cook Meth N/S 8002700, 215, 4, 0.00%, Pepper, bell-Cooked; Fresh or N/S; Boiled/baked 4013550, 110, 4, 0.00%, Spinach-Uncooked; Fresh or N/S; Cook Meth N/S10001990, 110, 3, 0.00%, Lemon-Uncooked; Fresh or N/S; Cook Meth N/S 6010430, 240, 2, 0.00%, Bean, snap, succulent-Cooked; Canned; Cook Meth N/S10001070, 110, 1, 0.00%, Citrus hybrids-Uncooked; Fresh or N/S; Cook MethN/S 8001480, 213, 2, 0.00%, Eggplant-Cooked; Fresh or N/S; Fried10002000, 130, 2, 0.00%, Lemon, juice-Uncooked; Dried; Cook Meth N/S11000080, 213, 3, 0.00%, Apple, peeled fruit-Cooked; Fresh or N/S; Fried11000090, 130, 2, 0.00%, Apple, dried-Uncooked; Dried; Cook Meth N/S10001810, 120, 1, 0.00%, Grapefruit, juice-Uncooked; Frozen; Cook Meth N/S12000140, 110, 2, 0.00%, Apricot, juice-Uncooked; Fresh or N/S; Cook MethN/S11002670, 130, 2, 0.00%, Pear, dried-Uncooked; Dried; Cook Meth N/S 8002340, 240, 1, 0.00%, Okra-Cooked; Canned; Cook Meth N/S10002000, 211, 2, 0.00%, Lemon, juice-Cooked; Fresh or N/S; Baked

304

95001750, 120, 2, 0.00%, Grape-Uncooked; Frozen; Cook Meth N/S 8001480, 211, 1, 0.00%, Eggplant-Cooked; Fresh or N/S; Baked 8002720, 221, 1, 0.00%, Pepper, nonbell-Cooked; Frozen; Baked10002000, 210, 2, 0.00%, Lemon, juice-Cooked; Fresh or N/S; Cook Meth N/S 9013990, 110, 2, 0.00%, Watermelon-Uncooked; Fresh or N/S; Cook Meth N/S11000100, 240, 3, 0.00%, Apple, juice-Cooked; Canned; Cook Meth N/S95002810, 120, 2, 0.00%, Pineapple, juice-Uncooked; Frozen; Cook Meth N/S 8002340, 212, 1, 0.00%, Okra-Cooked; Fresh or N/S; Boiled 4013550, 211, 1, 0.00%, Spinach-Cooked; Fresh or N/S; Baked95003600, 211, 1, 0.00%, Strawberry, juice-Cooked; Fresh or N/S; Baked 6010430, 110, 1, 0.00%, Bean, snap, succulent-Uncooked; Fresh or N/S; CookMeth N/S15003240, 232, 2, 0.00%, Rice, brown-Cooked; Dried; Boiled10003700, 110, 1, 0.00%, Tangerine, juice-Uncooked; Fresh or N/S; Cook MethN/S95000730, 110, 1, 0.00%, Cactus-Uncooked; Fresh or N/S; Cook Meth N/S11000080, 210, 1, 0.00%, Apple, peeled fruit-Cooked; Fresh or N/S; Cook MethN/S11000110, 240, 1, 0.00%, Apple, sauce-Cooked; Canned; Cook Meth N/S10003700, 240, 1, 0.00%, Tangerine, juice-Cooked; Canned; Cook Meth N/S13013210, 120, 1, 0.00%, Raspberry, juice-Uncooked; Frozen; Cook Meth N/S 8003770, 210, 1, 0.00%, Tomato, puree-Cooked; Fresh or N/S; Cook Meth N/S 4013550, 222, 1, 0.00%, Spinach-Cooked; Frozen; Boiled10002070, 240, 1, 0.00%, Lime, juice-Cooked; Canned; Cook Meth N/S 9021350, 212, 1, 0.00%, Cucumber-Cooked; Fresh or N/S; Boiled12000910, 110, 1, 0.00%, Cherry, juice-Uncooked; Fresh or N/S; Cook Meth N/S25002930, 210, 1, 0.00%, Pork, fat-Cooked; Fresh or N/S; Cook Meth N/S95001780, 230, 1, 0.00%, Grape, raisin-Cooked; Dried; Cook Meth N/S12000140, 120, 1, 0.00%, Apricot, juice-Uncooked; Frozen; Cook Meth N/S95002790, 210, 1, 0.00%, Pineapple-Cooked; Fresh or N/S; Cook Meth N/S 1033660, 210, 1, 0.00%, Sweet potato-Cooked; Fresh or N/S; Cook Meth N/S13010580, 240, 1, 0.00%, Boysenberry-Cooked; Canned; Cook Meth N/S 8003790, 240, 1, 0.00%, Tomato, juice-Cooked; Canned; Cook Meth N/S10002070, 120, 1, 0.00%, Lime, juice-Uncooked; Frozen; Cook Meth N/S 4011380, 110, 1, 0.00%, Dandelion, leaves-Uncooked; Fresh or N/S; Cook MethN/S95001760, 210, 1, 0.00%, Grape, juice-Cooked; Fresh or N/S; Cook Meth N/S 9021350, 150, 1, 0.00%, Cucumber-Uncooked; Cured etc; Cook Meth N/S15003250, 232, 1, 0.00%, Rice, flour-Cooked; Dried; Boiled 1033660, 215, 1, 0.00%, Sweet potato-Cooked; Fresh or N/S; Boiled/baked 8002700, 240, 1, 0.00%, Pepper, bell-Cooked; Canned; Cook Meth N/S15001240, 240, 1, 0.00%, Corn, field, syrup-Cooked; Canned; Cook Meth N/S10003700, 120, 1, 0.00%, Tangerine, juice-Uncooked; Frozen; Cook Meth N/S 4011500, 110, 1, 0.00%, Endive-Uncooked; Fresh or N/S; Cook Meth N/S 1010780, 110, 1, 0.00%, Carrot-Uncooked; Fresh or N/S; Cook Meth N/S

305

V-4. Acute Dietary Exposures and Risk Estimates - Monte Carlo Approach

California Department of Pesticide Regulation Ver. 2.02DEEM-FCID ACUTE Analysis for CARBARYL (1994-98 data)Residue file: cbl point estimate 1.R98 Adjustment factor #2 used.Analysis Date: 12-10-2009/12:04:22 Residue file dated: 12-10-2009/10:36:46/14NOEL (Acute) = 0.250000 mg/kg body-wt/dayDaily totals for food and foodform consumption used.MC iterations = 500 MC list in residue file MC seed = 10Run Comment: "Carbaryl monte carlo run #11 - 12.10.09"===============================================================================

U.S. Population Daily Exposure Analysis /a--------------- (mg/kg body-weight/day) per Capita per User ----------- ----------- Mean 0.000128 0.000128 Standard Deviation 0.000470 0.000470 Margin of Exposure 2/ 1,953 1,950

Percent of Person-Days that are User-Days = 99.86%

Estimated percentile of user-days falling below calculated exposure in mg/kg body-wt/day with Margin of Exposure (MOE)

Percentile Exposure MOE Percentile Exposure MOE ---------- ---------- --------- ---------- ---------- --------- 10.00 0.000014 18,227 90.00 0.000228 1,096 20.00 0.000021 12,089 95.00 0.000432 578 30.00 0.000028 8,962 97.50 0.000768 325 40.00 0.000036 6,925 99.00 0.001579 158 50.00 0.000046 5,491 99.50 0.002424 103 60.00 0.000059 4,251 99.75 0.003548 70 70.00 0.000078 3,194 99.90 0.006066 41 80.00 0.000118 2,126

Estimated percentile of per-capita days falling below calculated exposure in mg/kg body-wt/day with Margin of Exposure (MOE)

Percentile Exposure MOE Percentile Exposure MOE ---------- ---------- --------- ---------- ---------- --------- 10.00 0.000014 18,362 90.00 0.000228 1,097 20.00 0.000021 12,136 95.00 0.000431 579 30.00 0.000028 8,986 97.50 0.000767 325 40.00 0.000036 6,941 99.00 0.001578 158 50.00 0.000045 5,500 99.50 0.002423 103 60.00 0.000059 4,258 99.75 0.003546 70 70.00 0.000078 3,198 99.90 0.006038 41 80.00 0.000117 2,129-------------------------------------------------------------------------------a/ Analysis based on all two-day participant records in CSFII 1994-98 with 2 days of valid drinking water records.2/ Margin of Exposure = NOEL/ Dietary Exposure.

306

Western region Daily Exposure Analysis -------------- (mg/kg body-weight/day) per Capita per User ----------- ----------- Mean 0.000153 0.000154 Standard Deviation 0.000616 0.000617 Margin of Exposure 1,631 1,627

Percent of Person-Days that are User-Days = 99.76%

Estimated percentile of user-days falling below calculated exposure in mg/kg body-wt/day with Margin of Exposure (MOE)

Percentile Exposure MOE Percentile Exposure MOE ---------- ---------- --------- ---------- ---------- --------- 10.00 0.000015 17,036 90.00 0.000270 927 20.00 0.000022 11,395 95.00 0.000551 453 30.00 0.000030 8,417 97.50 0.001008 247 40.00 0.000039 6,464 99.00 0.001968 127 50.00 0.000049 5,117 99.50 0.003027 82 60.00 0.000065 3,849 99.75 0.004241 58 70.00 0.000087 2,861 99.90 0.007500 33 80.00 0.000134 1,871

Estimated percentile of per-capita days falling below calculated exposure in mg/kg body-wt/day with Margin of Exposure (MOE)

Percentile Exposure MOE Percentile Exposure MOE ---------- ---------- --------- ---------- ---------- --------- 10.00 0.000014 17,255 90.00 0.000269 928 20.00 0.000022 11,475 95.00 0.000550 454 30.00 0.000030 8,461 97.50 0.001004 248 40.00 0.000039 6,484 99.00 0.001957 127 50.00 0.000049 5,132 99.50 0.003027 82 60.00 0.000065 3,859 99.75 0.004238 58 70.00 0.000087 2,868 99.90 0.007500 33 80.00 0.000133 1,877

307

Hispanics Daily Exposure Analysis --------- (mg/kg body-weight/day) per Capita per User ----------- ----------- Mean 0.000150 0.000150 Standard Deviation 0.000453 0.000453 Margin of Exposure 1,670 1,668

Percent of Person-Days that are User-Days = 99.89%

Estimated percentile of user-days falling below calculated exposure in mg/kg body-wt/day with Margin of Exposure (MOE)

Percentile Exposure MOE Percentile Exposure MOE ---------- ---------- --------- ---------- ---------- --------- 10.00 0.000014 17,407 90.00 0.000287 871 20.00 0.000024 10,532 95.00 0.000511 489 30.00 0.000033 7,559 97.50 0.000921 271 40.00 0.000043 5,831 99.00 0.001827 136 50.00 0.000055 4,507 99.50 0.002332 107 60.00 0.000074 3,371 99.75 0.003195 78 70.00 0.000101 2,477 99.90 0.007651 32 80.00 0.000152 1,639

Estimated percentile of per-capita days falling below calculated exposure in mg/kg body-wt/day with Margin of Exposure (MOE)

Percentile Exposure MOE Percentile Exposure MOE ---------- ---------- --------- ---------- ---------- --------- 10.00 0.000014 17,565 90.00 0.000286 873 20.00 0.000024 10,570 95.00 0.000510 489 30.00 0.000033 7,576 97.50 0.000920 271 40.00 0.000043 5,841 99.00 0.001827 136 50.00 0.000055 4,514 99.50 0.002332 107 60.00 0.000074 3,375 99.75 0.003195 78 70.00 0.000101 2,480 99.90 0.007568 33 80.00 0.000152 1,641

308

Non-hispanic whites Daily Exposure Analysis ------------------- (mg/kg body-weight/day) per Capita per User ----------- ----------- Mean 0.000119 0.000119 Standard Deviation 0.000474 0.000474 Margin of Exposure 2,095 2,092

Percent of Person-Days that are User-Days = 99.85%

Estimated percentile of user-days falling below calculated exposure in mg/kg body-wt/day with Margin of Exposure (MOE)

Percentile Exposure MOE Percentile Exposure MOE ---------- ---------- --------- ---------- ---------- --------- 10.00 0.000014 18,074 90.00 0.000207 1,205 20.00 0.000020 12,256 95.00 0.000391 638 30.00 0.000027 9,214 97.50 0.000678 368 40.00 0.000035 7,207 99.00 0.001410 177 50.00 0.000044 5,741 99.50 0.002325 107 60.00 0.000055 4,522 99.75 0.003345 74 70.00 0.000073 3,424 99.90 0.006483 38 80.00 0.000108 2,308

Estimated percentile of per-capita days falling below calculated exposure in mg/kg body-wt/day with Margin of Exposure (MOE)

Percentile Exposure MOE Percentile Exposure MOE ---------- ---------- --------- ---------- ---------- --------- 10.00 0.000014 18,202 90.00 0.000207 1,207 20.00 0.000020 12,302 95.00 0.000391 639 30.00 0.000027 9,238 97.50 0.000677 369 40.00 0.000035 7,223 99.00 0.001409 177 50.00 0.000043 5,751 99.50 0.002320 107 60.00 0.000055 4,530 99.75 0.003345 74 70.00 0.000073 3,429 99.90 0.006482 38 80.00 0.000108 2,312

309

Non-hispanic blacks Daily Exposure Analysis ------------------- (mg/kg body-weight/day) per Capita per User ----------- ----------- Mean 0.000131 0.000131 Standard Deviation 0.000427 0.000427 Margin of Exposure 1,904 1,901

Percent of Person-Days that are User-Days = 99.87%

Estimated percentile of user-days falling below calculated exposure in mg/kg body-wt/day with Margin of Exposure (MOE)

Percentile Exposure MOE Percentile Exposure MOE ---------- ---------- --------- ---------- ---------- --------- 10.00 0.000012 20,662 90.00 0.000252 990 20.00 0.000020 12,524 95.00 0.000447 559 30.00 0.000029 8,675 97.50 0.000725 344 40.00 0.000039 6,445 99.00 0.001544 161 50.00 0.000050 5,001 99.50 0.002395 104 60.00 0.000065 3,842 99.75 0.003756 66 70.00 0.000087 2,862 99.90 0.005429 46 80.00 0.000128 1,953

Estimated percentile of per-capita days falling below calculated exposure in mg/kg body-wt/day with Margin of Exposure (MOE)

Percentile Exposure MOE Percentile Exposure MOE ---------- ---------- --------- ---------- ---------- --------- 10.00 0.000012 20,813 90.00 0.000252 991 20.00 0.000020 12,584 95.00 0.000446 560 30.00 0.000029 8,704 97.50 0.000724 345 40.00 0.000039 6,458 99.00 0.001544 161 50.00 0.000050 5,010 99.50 0.002393 104 60.00 0.000065 3,848 99.75 0.003755 66 70.00 0.000087 2,866 99.90 0.005428 46 80.00 0.000128 1,956

310

Non-hisp/non-white/non-black Daily Exposure Analysis ---------------------------- (mg/kg body-weight/day) per Capita per User ----------- ----------- Mean 0.000211 0.000211 Standard Deviation 0.000547 0.000547 Margin of Exposure 1,185 1,183

Percent of Person-Days that are User-Days = 99.83%

Estimated percentile of user-days falling below calculated exposure in mg/kg body-wt/day with Margin of Exposure (MOE)

Percentile Exposure MOE Percentile Exposure MOE ---------- ---------- --------- ---------- ---------- --------- 10.00 0.000014 18,082 90.00 0.000481 519 20.00 0.000022 11,549 95.00 0.001059 235 30.00 0.000030 8,376 97.50 0.001769 141 40.00 0.000039 6,489 99.00 0.003179 78 50.00 0.000051 4,865 99.50 0.003799 65 60.00 0.000069 3,634 99.75 0.004177 59 70.00 0.000098 2,545 99.90 0.005331 46 80.00 0.000172 1,450

Estimated percentile of per-capita days falling below calculated exposure in mg/kg body-wt/day with Margin of Exposure (MOE)

Percentile Exposure MOE Percentile Exposure MOE ---------- ---------- --------- ---------- ---------- --------- 10.00 0.000014 18,280 90.00 0.000480 520 20.00 0.000022 11,604 95.00 0.001058 236 30.00 0.000030 8,399 97.50 0.001769 141 40.00 0.000038 6,503 99.00 0.003163 79 50.00 0.000051 4,876 99.50 0.003799 65 60.00 0.000069 3,642 99.75 0.004168 59 70.00 0.000098 2,550 99.90 0.005330 46 80.00 0.000172 1,456

311

All infants Daily Exposure Analysis ----------- (mg/kg body-weight/day) per Capita per User ----------- ----------- Mean 0.000178 0.000195 Standard Deviation 0.000725 0.000758 Margin of Exposure 1,407 1,279

Percent of Person-Days that are User-Days = 90.95%

Estimated percentile of user-days falling below calculated exposure in mg/kg body-wt/day with Margin of Exposure (MOE)

Percentile Exposure MOE Percentile Exposure MOE ---------- ---------- --------- ---------- ---------- --------- 10.00 0.000005 52,364 90.00 0.000344 725 20.00 0.000018 13,753 95.00 0.000661 378 30.00 0.000031 7,937 97.50 0.001244 201 40.00 0.000047 5,316 99.00 0.002532 98 50.00 0.000066 3,762 99.50 0.003598 69 60.00 0.000090 2,771 99.75 0.005782 43 70.00 0.000120 2,082 99.90 0.010644 23 80.00 0.000172 1,452

Estimated percentile of per-capita days falling below calculated exposure in mg/kg body-wt/day with Margin of Exposure (MOE)

Percentile Exposure MOE Percentile Exposure MOE ---------- ---------- --------- ---------- ---------- --------- 10.00 0.000000 800,730 90.00 0.000310 806 20.00 0.000007 34,617 95.00 0.000612 408 30.00 0.000022 11,537 97.50 0.001163 214 40.00 0.000037 6,767 99.00 0.002295 108 50.00 0.000056 4,433 99.50 0.003317 75 60.00 0.000080 3,115 99.75 0.005769 43 70.00 0.000111 2,257 99.90 0.010621 23 80.00 0.000158 1,577

312

Nursing infants (<1 yr old) Daily Exposure Analysis --------------------------- (mg/kg body-weight/day) per Capita per User ----------- ----------- Mean 0.000076 0.000114 Standard Deviation 0.000507 0.000616 Margin of Exposure 3,268 2,190

Percent of Person-Days that are User-Days = 67.02%

Estimated percentile of user-days falling below calculated exposure in mg/kg body-wt/day with Margin of Exposure (MOE)

Percentile Exposure MOE Percentile Exposure MOE ---------- ---------- --------- ---------- ---------- --------- 10.00 0.000001 170,290 90.00 0.000228 1,097 20.00 0.000004 57,288 95.00 0.000431 579 30.00 0.000010 26,013 97.50 0.000772 323 40.00 0.000019 13,461 99.00 0.001308 191 50.00 0.000032 7,777 99.50 0.001648 151 60.00 0.000051 4,946 99.75 0.002257 110 70.00 0.000071 3,542 99.90 0.004201 59 80.00 0.000115 2,173

Estimated percentile of per-capita days falling below calculated exposure in mg/kg body-wt/day with Margin of Exposure (MOE)

Percentile Exposure MOE Percentile Exposure MOE ---------- ---------- --------- ---------- ---------- --------- 10.00 0.000000 >1,000,000 90.00 0.000156 1,601 20.00 0.000000 >1,000,000 95.00 0.000302 828 30.00 0.000000 >1,000,000 97.50 0.000594 420 40.00 0.000002 161,299 99.00 0.001156 216 50.00 0.000007 35,920 99.50 0.001618 154 60.00 0.000019 13,310 99.75 0.001935 129 70.00 0.000041 6,065 99.90 0.003241 77 80.00 0.000071 3,531

313

Non-nursing infants (<1 yr old) Daily Exposure Analysis ------------------------------- (mg/kg body-weight/day) per Capita per User ----------- ----------- Mean 0.000216 0.000216 Standard Deviation 0.000788 0.000789 Margin of Exposure 1,158 1,158

Percent of Person-Days that are User-Days = 99.98%

Estimated percentile of user-days falling below calculated exposure in mg/kg body-wt/day with Margin of Exposure (MOE)

Percentile Exposure MOE Percentile Exposure MOE ---------- ---------- --------- ---------- ---------- --------- 10.00 0.000012 20,655 90.00 0.000378 661 20.00 0.000025 10,185 95.00 0.000771 324 30.00 0.000039 6,493 97.50 0.001361 183 40.00 0.000055 4,525 99.00 0.002810 88 50.00 0.000076 3,272 99.50 0.004413 56 60.00 0.000100 2,506 99.75 0.005761 43 70.00 0.000131 1,907 99.90 0.012796 19 80.00 0.000184 1,355

Estimated percentile of per-capita days falling below calculated exposure in mg/kg body-wt/day with Margin of Exposure (MOE)

Percentile Exposure MOE Percentile Exposure MOE ---------- ---------- --------- ---------- ---------- --------- 10.00 0.000012 20,708 90.00 0.000378 661 20.00 0.000025 10,195 95.00 0.000771 324 30.00 0.000038 6,496 97.50 0.001361 183 40.00 0.000055 4,527 99.00 0.002810 88 50.00 0.000076 3,274 99.50 0.004411 56 60.00 0.000100 2,507 99.75 0.005761 43 70.00 0.000131 1,907 99.90 0.012796 19 80.00 0.000184 1,356

314

Females 13+ (preg/not nursing) Daily Exposure Analysis ------------------------------ (mg/kg body-weight/day) per Capita per User ----------- ----------- Mean 0.000119 0.000119 Standard Deviation 0.000305 0.000305 Margin of Exposure 2,096 2,096

Percent of Person-Days that are User-Days = 100.00%

Estimated percentile of user-days falling below calculated exposure in mg/kg body-wt/day with Margin of Exposure (MOE)

Percentile Exposure MOE Percentile Exposure MOE ---------- ---------- --------- ---------- ---------- --------- 10.00 0.000017 15,100 90.00 0.000228 1,095 20.00 0.000022 11,296 95.00 0.000373 670 30.00 0.000029 8,625 97.50 0.000748 334 40.00 0.000036 6,867 99.00 0.001983 126 50.00 0.000046 5,439 99.50 0.001987 125 60.00 0.000057 4,389 99.75 0.001990 125 70.00 0.000074 3,382 99.90 0.001991 125 80.00 0.000090 2,770

Estimated percentile of per-capita days falling below calculated exposure in mg/kg body-wt/day with Margin of Exposure (MOE)

Percentile Exposure MOE Percentile Exposure MOE ---------- ---------- --------- ---------- ---------- --------- 10.00 0.000017 15,100 90.00 0.000228 1,095 20.00 0.000022 11,296 95.00 0.000373 670 30.00 0.000029 8,625 97.50 0.000748 334 40.00 0.000036 6,867 99.00 0.001983 126 50.00 0.000046 5,439 99.50 0.001987 125 60.00 0.000057 4,389 99.75 0.001990 125 70.00 0.000074 3,382 99.90 0.001991 125 80.00 0.000090 2,770

315

Females 13+ (nursing) Daily Exposure Analysis --------------------- (mg/kg body-weight/day) per Capita per User ----------- ----------- Mean 0.000089 0.000089 Standard Deviation 0.000142 0.000142 Margin of Exposure 2,812 2,812

Percent of Person-Days that are User-Days = 100.00%

Estimated percentile of user-days falling below calculated exposure in mg/kg body-wt/day with Margin of Exposure (MOE)

Percentile Exposure MOE Percentile Exposure MOE ---------- ---------- --------- ---------- ---------- --------- 10.00 0.000016 15,582 90.00 0.000222 1,125 20.00 0.000020 12,527 95.00 0.000334 749 30.00 0.000028 8,807 97.50 0.000577 432 40.00 0.000034 7,295 99.00 0.000639 391 50.00 0.000041 6,048 99.50 0.000647 386 60.00 0.000053 4,697 99.75 0.000887 281 70.00 0.000069 3,639 99.90 0.001439 173 80.00 0.000104 2,406

Estimated percentile of per-capita days falling below calculated exposure in mg/kg body-wt/day with Margin of Exposure (MOE)

Percentile Exposure MOE Percentile Exposure MOE ---------- ---------- --------- ---------- ---------- --------- 10.00 0.000016 15,582 90.00 0.000222 1,125 20.00 0.000020 12,527 95.00 0.000334 749 30.00 0.000028 8,807 97.50 0.000577 432 40.00 0.000034 7,295 99.00 0.000639 391 50.00 0.000041 6,048 99.50 0.000647 386 60.00 0.000053 4,697 99.75 0.000887 281 70.00 0.000069 3,639 99.90 0.001439 173 80.00 0.000104 2,406

316

Children 1-2 yrs Daily Exposure Analysis ---------------- (mg/kg body-weight/day) per Capita per User ----------- ----------- Mean 0.000292 0.000292 Standard Deviation 0.000932 0.000932 Margin of Exposure 857 857

Percent of Person-Days that are User-Days = 100.00%

Estimated percentile of user-days falling below calculated exposure in mg/kg body-wt/day with Margin of Exposure (MOE)

Percentile Exposure MOE Percentile Exposure MOE ---------- ---------- --------- ---------- ---------- --------- 10.00 0.000055 4,533 90.00 0.000587 425 20.00 0.000077 3,264 95.00 0.000905 276 30.00 0.000097 2,589 97.50 0.001319 189 40.00 0.000117 2,135 99.00 0.002291 109 50.00 0.000140 1,783 99.50 0.003294 75 60.00 0.000172 1,457 99.75 0.004753 52 70.00 0.000221 1,129 99.90 0.010476 23 80.00 0.000321 779

Estimated percentile of per-capita days falling below calculated exposure in mg/kg body-wt/day with Margin of Exposure (MOE)

Percentile Exposure MOE Percentile Exposure MOE ---------- ---------- --------- ---------- ---------- --------- 10.00 0.000055 4,533 90.00 0.000587 425 20.00 0.000077 3,264 95.00 0.000905 276 30.00 0.000097 2,589 97.50 0.001319 189 40.00 0.000117 2,135 99.00 0.002291 109 50.00 0.000140 1,783 99.50 0.003294 75 60.00 0.000172 1,457 99.75 0.004753 52 70.00 0.000221 1,129 99.90 0.010476 23 80.00 0.000321 779

317

Children 3-5 yrs Daily Exposure Analysis ---------------- (mg/kg body-weight/day) per Capita per User ----------- ----------- Mean 0.000273 0.000273 Standard Deviation 0.001024 0.001024 Margin of Exposure 916 916

Percent of Person-Days that are User-Days = 100.00%

Estimated percentile of user-days falling below calculated exposure in mg/kg body-wt/day with Margin of Exposure (MOE)

Percentile Exposure MOE Percentile Exposure MOE ---------- ---------- --------- ---------- ---------- --------- 10.00 0.000055 4,572 90.00 0.000499 500 20.00 0.000072 3,455 95.00 0.000799 313 30.00 0.000091 2,758 97.50 0.001227 203 40.00 0.000109 2,283 99.00 0.002066 121 50.00 0.000132 1,894 99.50 0.003382 73 60.00 0.000162 1,541 99.75 0.006365 39 70.00 0.000207 1,208 99.90 0.008455 29 80.00 0.000289 864

Estimated percentile of per-capita days falling below calculated exposure in mg/kg body-wt/day with Margin of Exposure (MOE)

Percentile Exposure MOE Percentile Exposure MOE ---------- ---------- --------- ---------- ---------- --------- 10.00 0.000055 4,572 90.00 0.000499 500 20.00 0.000072 3,455 95.00 0.000799 313 30.00 0.000091 2,758 97.50 0.001227 203 40.00 0.000109 2,283 99.00 0.002066 121 50.00 0.000132 1,894 99.50 0.003382 73 60.00 0.000162 1,541 99.75 0.006365 39 70.00 0.000207 1,208 99.90 0.008455 29 80.00 0.000289 864

318

Children 6-12 yrs Daily Exposure Analysis ----------------- (mg/kg body-weight/day) per Capita per User ----------- ----------- Mean 0.000170 0.000170 Standard Deviation 0.000419 0.000419 Margin of Exposure 1,468 1,468

Percent of Person-Days that are User-Days = 100.00%

Estimated percentile of user-days falling below calculated exposure in mg/kg body-wt/day with Margin of Exposure (MOE)

Percentile Exposure MOE Percentile Exposure MOE ---------- ---------- --------- ---------- ---------- --------- 10.00 0.000033 7,497 90.00 0.000328 761 20.00 0.000046 5,455 95.00 0.000524 477 30.00 0.000058 4,322 97.50 0.000832 300 40.00 0.000070 3,584 99.00 0.001393 179 50.00 0.000084 2,967 99.50 0.002065 121 60.00 0.000103 2,422 99.75 0.003361 74 70.00 0.000134 1,858 99.90 0.007275 34 80.00 0.000192 1,302

Estimated percentile of per-capita days falling below calculated exposure in mg/kg body-wt/day with Margin of Exposure (MOE)

Percentile Exposure MOE Percentile Exposure MOE ---------- ---------- --------- ---------- ---------- --------- 10.00 0.000033 7,497 90.00 0.000328 761 20.00 0.000046 5,455 95.00 0.000524 477 30.00 0.000058 4,322 97.50 0.000832 300 40.00 0.000070 3,584 99.00 0.001393 179 50.00 0.000084 2,967 99.50 0.002065 121 60.00 0.000103 2,422 99.75 0.003361 74 70.00 0.000134 1,858 99.90 0.007275 34 80.00 0.000192 1,302

319

Youth 13-19 yrs Daily Exposure Analysis --------------- (mg/kg body-weight/day) per Capita per User ----------- ----------- Mean 0.000108 0.000108 Standard Deviation 0.000315 0.000315 Margin of Exposure 2,305 2,305

Percent of Person-Days that are User-Days = 100.00%

Estimated percentile of user-days falling below calculated exposure in mg/kg body-wt/day with Margin of Exposure (MOE)

Percentile Exposure MOE Percentile Exposure MOE ---------- ---------- --------- ---------- ---------- --------- 10.00 0.000018 13,975 90.00 0.000191 1,307 20.00 0.000026 9,675 95.00 0.000357 700 30.00 0.000034 7,432 97.50 0.000571 438 40.00 0.000042 5,962 99.00 0.001209 206 50.00 0.000051 4,938 99.50 0.001747 143 60.00 0.000062 4,026 99.75 0.002427 103 70.00 0.000077 3,265 99.90 0.004290 58 80.00 0.000103 2,422

Estimated percentile of per-capita days falling below calculated exposure in mg/kg body-wt/day with Margin of Exposure (MOE)

Percentile Exposure MOE Percentile Exposure MOE ---------- ---------- --------- ---------- ---------- --------- 10.00 0.000018 13,975 90.00 0.000191 1,307 20.00 0.000026 9,675 95.00 0.000357 700 30.00 0.000034 7,432 97.50 0.000571 438 40.00 0.000042 5,962 99.00 0.001209 206 50.00 0.000051 4,938 99.50 0.001747 143 60.00 0.000062 4,026 99.75 0.002427 103 70.00 0.000077 3,265 99.90 0.004290 58 80.00 0.000103 2,422

320

Adults 20-49 yrs Daily Exposure Analysis ---------------- (mg/kg body-weight/day) per Capita per User ----------- ----------- Mean 0.000100 0.000100 Standard Deviation 0.000317 0.000317 Margin of Exposure 2,495 2,494

Percent of Person-Days that are User-Days = 99.98%

Estimated percentile of user-days falling below calculated exposure in mg/kg body-wt/day with Margin of Exposure (MOE)

Percentile Exposure MOE Percentile Exposure MOE ---------- ---------- --------- ---------- ---------- --------- 10.00 0.000013 19,722 90.00 0.000172 1,449 20.00 0.000019 13,135 95.00 0.000345 725 30.00 0.000025 9,862 97.50 0.000589 424 40.00 0.000032 7,802 99.00 0.001255 199 50.00 0.000039 6,334 99.50 0.001902 131 60.00 0.000049 5,136 99.75 0.003058 81 70.00 0.000063 3,999 99.90 0.003584 69 80.00 0.000088 2,843

Estimated percentile of per-capita days falling below calculated exposure in mg/kg body-wt/day with Margin of Exposure (MOE)

Percentile Exposure MOE Percentile Exposure MOE ---------- ---------- --------- ---------- ---------- --------- 10.00 0.000013 19,741 90.00 0.000172 1,449 20.00 0.000019 13,141 95.00 0.000345 725 30.00 0.000025 9,865 97.50 0.000589 424 40.00 0.000032 7,804 99.00 0.001255 199 50.00 0.000039 6,335 99.50 0.001902 131 60.00 0.000049 5,137 99.75 0.003058 81 70.00 0.000062 4,000 99.90 0.003584 69 80.00 0.000088 2,843

321

Adults 50+ yrs Daily Exposure Analysis -------------- (mg/kg body-weight/day) per Capita per User ----------- ----------- Mean 0.000119 0.000119 Standard Deviation 0.000494 0.000494 Margin of Exposure 2,100 2,099

Percent of Person-Days that are User-Days = 99.98%

Estimated percentile of user-days falling below calculated exposure in mg/kg body-wt/day with Margin of Exposure (MOE)

Percentile Exposure MOE Percentile Exposure MOE ---------- ---------- --------- ---------- ---------- --------- 10.00 0.000011 22,896 90.00 0.000154 1,623 20.00 0.000016 15,627 95.00 0.000329 758 30.00 0.000021 12,086 97.50 0.000861 290 40.00 0.000026 9,699 99.00 0.002170 115 50.00 0.000032 7,867 99.50 0.003300 75 60.00 0.000040 6,296 99.75 0.005172 48 70.00 0.000051 4,911 99.90 0.007442 33 80.00 0.000072 3,448

Estimated percentile of per-capita days falling below calculated exposure in mg/kg body-wt/day with Margin of Exposure (MOE)

Percentile Exposure MOE Percentile Exposure MOE ---------- ---------- --------- ---------- ---------- --------- 10.00 0.000011 22,914 90.00 0.000154 1,624 20.00 0.000016 15,634 95.00 0.000329 758 30.00 0.000021 12,089 97.50 0.000861 290 40.00 0.000026 9,701 99.00 0.002170 115 50.00 0.000032 7,869 99.50 0.003300 75 60.00 0.000040 6,297 99.75 0.005172 48 70.00 0.000051 4,911 99.90 0.007442 33 80.00 0.000072 3,449

322

Females 13-49 yrs Daily Exposure Analysis ----------------- (mg/kg body-weight/day) per Capita per User ----------- ----------- Mean 0.000098 0.000098 Standard Deviation 0.000330 0.000330 Margin of Exposure 2,558 2,558

Percent of Person-Days that are User-Days = 100.00%

Estimated percentile of user-days falling below calculated exposure in mg/kg body-wt/day with Margin of Exposure (MOE)

Percentile Exposure MOE Percentile Exposure MOE ---------- ---------- --------- ---------- ---------- --------- 10.00 0.000012 21,460 90.00 0.000175 1,425 20.00 0.000018 14,055 95.00 0.000325 769 30.00 0.000024 10,545 97.50 0.000576 433 40.00 0.000030 8,253 99.00 0.001240 201 50.00 0.000038 6,580 99.50 0.001731 144 60.00 0.000047 5,294 99.75 0.002812 88 70.00 0.000062 4,059 99.90 0.003564 70 80.00 0.000085 2,941

Estimated percentile of per-capita days falling below calculated exposure in mg/kg body-wt/day with Margin of Exposure (MOE)

Percentile Exposure MOE Percentile Exposure MOE ---------- ---------- --------- ---------- ---------- --------- 10.00 0.000012 21,460 90.00 0.000175 1,425 20.00 0.000018 14,055 95.00 0.000325 769 30.00 0.000024 10,545 97.50 0.000576 433 40.00 0.000030 8,253 99.00 0.001240 201 50.00 0.000038 6,580 99.50 0.001731 144 60.00 0.000047 5,294 99.75 0.002812 88 70.00 0.000062 4,059 99.90 0.003564 70 80.00 0.000085 2,941

323

Custom demographics 1: Adults 16-70 yrAll SeasonsAll RegionsSex: M/F-all/All RacesAge-Low: 16 yrs High: 70 yrs--------------------------------------

Daily Exposure Analysis (mg/kg body-weight/day) per Capita per User ----------- ----------- Mean 0.000104 0.000104 Standard Deviation 0.000354 0.000354 Margin of Exposure 2,397 2,397

Percent of Person-Days that are User-Days = 99.98%

Estimated percentile of user-days falling below calculated exposure in mg/kg body-wt/day with Margin of Exposure (MOE)

Percentile Exposure MOE Percentile Exposure MOE ---------- ---------- --------- ---------- ---------- --------- 10.00 0.000012 20,319 90.00 0.000171 1,462 20.00 0.000018 13,549 95.00 0.000344 725 30.00 0.000024 10,274 97.50 0.000619 403 40.00 0.000031 8,106 99.00 0.001403 178 50.00 0.000038 6,524 99.50 0.002219 112 60.00 0.000047 5,271 99.75 0.003223 77 70.00 0.000061 4,086 99.90 0.004354 57 80.00 0.000086 2,917

Estimated percentile of per-capita days falling below calculated exposure in mg/kg body-wt/day with Margin of Exposure (MOE)

Percentile Exposure MOE Percentile Exposure MOE ---------- ---------- --------- ---------- ---------- --------- 10.00 0.000012 20,335 90.00 0.000171 1,463 20.00 0.000018 13,554 95.00 0.000344 726 30.00 0.000024 10,276 97.50 0.000619 403 40.00 0.000031 8,107 99.00 0.001403 178 50.00 0.000038 6,525 99.50 0.002219 112 60.00 0.000047 5,272 99.75 0.003223 77 70.00 0.000061 4,086 99.90 0.004353 57 80.00 0.000086 2,917

324

V-5. Acute Dietary Critical Exposure Contribution Analysis - Monte Carlo Approach California Department of Pesticide RegulationDEEM-FCID Acute Critical Exposure Contribution Analysis (Ver 2.02)CSFII 1994-98Residue file = H:\ARubin\Corel\CARBARYL\NEW DIETARY August 2009\DEEM files\cbl pointestimate 1.R98Acute report = H:\ARubin\Corel\CARBARYL\NEW DIETARY August 2009\DEEM files\CLmc11.AC7Date and time of analysis: 12-10-2009 11:58:10Daily totals for food and foodform consumption used.Adjustment factor #2 used.Minimum exposure contribution = 1%Monte Carlo Iterations = 500 Seed = 10CEC records generated for first 19 iterations.Exposures divided by body weight

Subpopulations: 1 U.S. Population 2 Western region 3 Hispanics 4 Non-hispanic whites 5 Non-hispanic blacks 6 Non-hisp/non-white/non-black 7 All infants 8 Nursing infants (<1 yr old) 9 Non-nursing infants (<1 yr old) 10 Females 13+ (preg/not nursing) 11 Females 13+ (nursing) 12 Children 1-2 yrs 13 Children 3-5 yrs 14 Children 6-12 yrs 15 Youth 13-19 yrs 16 Adults 20-49 yrs 17 Adults 50+ yrs 18 Females 13-49 yrs 19 Custom demographics 1: Adults 16-70 yr

================================================================================U.S. PopulationLow percentile for CEC records: 95 Exposure (mg/day) = 0.000431High percentile for CEC records: 100 Exposure (mg/day) = 0.236331Number of actual records in this interval: 57108

Critical foods/foodforms for this population (as derived from these records): N=number of appearances in all records (including duplicates) %=percent of total exposure for all records (including duplicates)

Food, FF, N , Percent, Food Name --------, ---, -----, -------, -------------12000910, 210, 9365, 6.52%, Cherry, juice-Cooked; Fresh or N/S; Cook Meth N/S12002880, 110, 1619, 6.41%, Plum, prune, juice-Uncooked; Fresh or N/S; CookMeth N/S10002000, 110, 7173, 4.86%, Lemon, juice-Uncooked; Fresh or N/S; Cook Meth N/S 5022290, 212, 1242, 4.50%, Mustard greens-Cooked; Fresh or N/S; Boiled12000910, 110, 629, 3.64%, Cherry, juice-Uncooked; Fresh or N/S; Cook Meth N/S95002810, 110, 3881, 3.14%, Pineapple, juice-Uncooked; Fresh or N/S; Cook MethN/S11000070, 110, 2219, 2.73%, Apple, fruit with peel-Uncooked; Fresh or N/S; CookMeth N/S 8002720, 110, 2653, 2.71%, Pepper, nonbell-Uncooked; Fresh or N/S; Cook MethN/S12002620, 110, 475, 2.23%, Peach, juice-Uncooked; Fresh or N/S; Cook Meth N/S 8002340, 210, 1070, 1.96%, Okra-Cooked; Fresh or N/S; Cook Meth N/S

325

10001810, 110, 2682, 1.93%, Grapefruit, juice-Uncooked; Fresh or N/S; Cook MethN/S 4023220, 240, 152, 1.84%, Rhubarb-Cooked; Canned; Cook Meth N/S 5020700, 210, 1226, 1.71%, Cabbage, Chinese, bok choy-Cooked; Fresh or N/S;Cook Meth N/S95002810, 240, 7433, 1.64%, Pineapple, juice-Cooked; Canned; Cook Meth N/S13021910, 110, 19, 1.60%, Huckleberry-Uncooked; Fresh or N/S; Cook Meth N/S12002610, 130, 460, 1.58%, Peach, dried-Uncooked; Dried; Cook Meth N/S10003690, 110, 1630, 1.55%, Tangerine-Uncooked; Fresh or N/S; Cook Meth N/S10002000, 210, 9460, 1.48%, Lemon, juice-Cooked; Fresh or N/S; Cook Meth N/S95001750, 110, 787, 1.39%, Grape-Uncooked; Fresh or N/S; Cook Meth N/S 4023220, 211, 437, 1.34%, Rhubarb-Cooked; Fresh or N/S; Baked 8002720, 210, 2677, 1.29%, Pepper, nonbell-Cooked; Fresh or N/S; Cook Meth N/S 5022290, 242, 191, 1.29%, Mustard greens-Cooked; Canned; Boiled12000911, 240, 1034, 1.26%, Cherry, juice-babyfood-Cooked; Canned; Cook MethN/S12002620, 240, 324, 1.21%, Peach, juice-Cooked; Canned; Cook Meth N/S11000100, 110, 6354, 1.13%, Apple, juice-Uncooked; Fresh or N/S; Cook Meth N/S 4023670, 212, 190, 1.12%, Swiss chard-Cooked; Fresh or N/S; Boiled 5020700, 150, 665, 1.12%, Cabbage, Chinese, bok choy-Uncooked; Cured etc;Cook Meth N/S13020570, 211, 638, 1.05%, Blueberry-Cooked; Fresh or N/S; Baked 8002340, 220, 514, 0.98%, Okra-Cooked; Frozen; Cook Meth N/S10003700, 240, 6328, 0.93%, Tangerine, juice-Cooked; Canned; Cook Meth N/S12002881, 240, 380, 0.86%, Plum, prune, juice-babyfood-Cooked; Canned; CookMeth N/S13020570, 110, 481, 0.86%, Blueberry-Uncooked; Fresh or N/S; Cook Meth N/S10002000, 240, 6301, 0.77%, Lemon, juice-Cooked; Canned; Cook Meth N/S11000090, 211, 1893, 0.73%, Apple, dried-Cooked; Fresh or N/S; Baked 4020860, 110, 171, 0.67%, Celery, juice-Uncooked; Fresh or N/S; Cook Meth N/S10002000, 130, 1546, 0.63%, Lemon, juice-Uncooked; Dried; Cook Meth N/S13010580, 240, 5492, 0.61%, Boysenberry-Cooked; Canned; Cook Meth N/S10002070, 240, 5427, 0.60%, Lime, juice-Cooked; Canned; Cook Meth N/S 8002720, 212, 1715, 0.60%, Pepper, nonbell-Cooked; Fresh or N/S; Boiled13013200, 240, 615, 0.60%, Raspberry-Cooked; Canned; Cook Meth N/S 8002720, 213, 859, 0.57%, Pepper, nonbell-Cooked; Fresh or N/S; Fried12002600, 240, 736, 0.54%, Peach-Cooked; Canned; Cook Meth N/S10002070, 110, 913, 0.54%, Lime, juice-Uncooked; Fresh or N/S; Cook Meth N/S11000090, 130, 518, 0.54%, Apple, dried-Uncooked; Dried; Cook Meth N/S95002350, 240, 198, 0.53%, Olive-Cooked; Canned; Cook Meth N/S10001810, 240, 4323, 0.52%, Grapefruit, juice-Cooked; Canned; Cook Meth N/S25002930, 210, 8147, 0.50%, Pork, fat-Cooked; Fresh or N/S; Cook Meth N/S 5022290, 222, 95, 0.50%, Mustard greens-Cooked; Frozen; Boiled12002601, 240, 315, 0.50%, Peach-babyfood-Cooked; Canned; Cook Meth N/S12000910, 240, 3304, 0.49%, Cherry, juice-Cooked; Canned; Cook Meth N/S95001760, 240, 5167, 0.46%, Grape, juice-Cooked; Canned; Cook Meth N/S27002220, 110, 18562, 0.46%, Milk, fat-Uncooked; Fresh or N/S; Cook Meth N/S 8002340, 213, 500, 0.45%, Okra-Cooked; Fresh or N/S; Fried 8002720, 240, 1731, 0.43%, Pepper, nonbell-Cooked; Canned; Cook Meth N/S95001760, 110, 2374, 0.41%, Grape, juice-Uncooked; Fresh or N/S; Cook Meth N/S12002600, 110, 426, 0.38%, Peach-Uncooked; Fresh or N/S; Cook Meth N/S15003251, 230, 1879, 0.37%, Rice, flour-babyfood-Cooked; Dried; Cook Meth N/S13020571, 240, 114, 0.36%, Blueberry-babyfood-Cooked; Canned; Cook Meth N/S 9010800, 110, 76, 0.35%, Casaba-Uncooked; Fresh or N/S; Cook Meth N/S12002621, 240, 190, 0.33%, Peach, juice-babyfood-Cooked; Canned; Cook Meth N/S13010580, 120, 1141, 0.33%, Boysenberry-Uncooked; Frozen; Cook Meth N/S11000110, 212, 1535, 0.32%, Apple, sauce-Cooked; Fresh or N/S; Boiled25002930, 213, 3545, 0.31%, Pork, fat-Cooked; Fresh or N/S; Fried95002811, 240, 1015, 0.29%, Pineapple, juice-babyfood-Cooked; Canned; Cook MethN/S15001240, 240, 13327, 0.29%, Corn, field, syrup-Cooked; Canned; Cook Meth N/S11002660, 110, 199, 0.28%, Pear-Uncooked; Fresh or N/S; Cook Meth N/S10001810, 120, 1068, 0.28%, Grapefruit, juice-Uncooked; Frozen; Cook Meth N/S13013200, 110, 431, 0.27%, Raspberry-Uncooked; Fresh or N/S; Cook Meth N/S95002810, 120, 1231, 0.26%, Pineapple, juice-Uncooked; Frozen; Cook Meth N/S

326

9020880, 210, 247, 0.25%, Chayote, fruit-Cooked; Fresh or N/S; Cook Meth N/S10002410, 110, 5588, 0.25%, Orange, juice-Uncooked; Fresh or N/S; Cook Meth N/S15003250, 230, 2813, 0.25%, Rice, flour-Cooked; Dried; Cook Meth N/S11002670, 130, 441, 0.24%, Pear, dried-Uncooked; Dried; Cook Meth N/S25002930, 250, 4154, 0.24%, Pork, fat-Cooked; Cured etc; Cook Meth N/S10002000, 120, 1226, 0.23%, Lemon, juice-Uncooked; Frozen; Cook Meth N/S 8002700, 210, 418, 0.23%, Pepper, bell-Cooked; Fresh or N/S; Cook Meth N/S13010550, 240, 609, 0.22%, Blackberry-Cooked; Canned; Cook Meth N/S11000111, 240, 828, 0.22%, Apple, sauce-babyfood-Cooked; Canned; Cook Meth N/S15004020, 211, 13005, 0.21%, Wheat, flour-Cooked; Fresh or N/S; Baked 8002730, 210, 2265, 0.21%, Pepper, nonbell, dried-Cooked; Fresh or N/S; CookMeth N/S 4023220, 120, 38, 0.21%, Rhubarb-Uncooked; Frozen; Cook Meth N/S11002661, 240, 114, 0.20%, Pear-babyfood-Cooked; Canned; Cook Meth N/S11000100, 240, 3110, 0.19%, Apple, juice-Cooked; Canned; Cook Meth N/S11000101, 240, 1586, 0.19%, Apple, juice-babyfood-Cooked; Canned; Cook Meth N/S 8002340, 150, 153, 0.19%, Okra-Uncooked; Cured etc; Cook Meth N/S10003700, 110, 383, 0.18%, Tangerine, juice-Uncooked; Fresh or N/S; Cook MethN/S 8002700, 110, 356, 0.18%, Pepper, bell-Uncooked; Fresh or N/S; Cook Meth N/S10002070, 120, 1476, 0.18%, Lime, juice-Uncooked; Frozen; Cook Meth N/S 8002720, 150, 360, 0.16%, Pepper, nonbell-Uncooked; Cured etc; Cook Meth N/S11000091, 230, 284, 0.16%, Apple, dried-babyfood-Cooked; Dried; Cook Meth N/S11002660, 240, 178, 0.16%, Pear-Cooked; Canned; Cook Meth N/S95003590, 110, 218, 0.16%, Strawberry-Uncooked; Fresh or N/S; Cook Meth N/S11000090, 230, 969, 0.16%, Apple, dried-Cooked; Dried; Cook Meth N/S25002930, 211, 3266, 0.15%, Pork, fat-Cooked; Fresh or N/S; Baked13013210, 110, 60, 0.15%, Raspberry, juice-Uncooked; Fresh or N/S; Cook MethN/S25002930, 253, 2276, 0.15%, Pork, fat-Cooked; Cured etc; Fried13010580, 110, 249, 0.14%, Boysenberry-Uncooked; Fresh or N/S; Cook Meth N/S95002350, 211, 146, 0.14%, Olive-Cooked; Fresh or N/S; Baked10003700, 120, 1076, 0.14%, Tangerine, juice-Uncooked; Frozen; Cook Meth N/S 8002730, 212, 1529, 0.14%, Pepper, nonbell, dried-Cooked; Fresh or N/S; Boiled11000081, 240, 137, 0.12%, Apple, peeled fruit-babyfood-Cooked; Canned; CookMeth N/S21000470, 210, 5540, 0.12%, Beef, fat-Cooked; Fresh or N/S; Cook Meth N/S12000900, 110, 302, 0.11%, Cherry-Uncooked; Fresh or N/S; Cook Meth N/S95001750, 210, 449, 0.11%, Grape-Cooked; Fresh or N/S; Cook Meth N/S15003251, 240, 1197, 0.11%, Rice, flour-babyfood-Cooked; Canned; Cook Meth N/S13013200, 120, 66, 0.10%, Raspberry-Uncooked; Frozen; Cook Meth N/S13020570, 214, 54, 0.10%, Blueberry-Cooked; Fresh or N/S; Fried/baked12002300, 110, 87, 0.10%, Nectarine-Uncooked; Fresh or N/S; Cook Meth N/S21000440, 210, 4856, 0.09%, Beef, meat-Cooked; Fresh or N/S; Cook Meth N/S15001240, 110, 5817, 0.09%, Corn, field, syrup-Uncooked; Fresh or N/S; CookMeth N/S25002900, 250, 3464, 0.09%, Pork, meat-Cooked; Cured etc; Cook Meth N/S10002410, 120, 2146, 0.09%, Orange, juice-Uncooked; Frozen; Cook Meth N/S 8002720, 220, 57, 0.09%, Pepper, nonbell-Cooked; Frozen; Cook Meth N/S95003600, 240, 213, 0.09%, Strawberry, juice-Cooked; Canned; Cook Meth N/S 5020700, 110, 76, 0.09%, Cabbage, Chinese, bok choy-Uncooked; Fresh or N/S;Cook Meth N/S95002800, 130, 442, 0.08%, Pineapple, dried-Uncooked; Dried; Cook Meth N/S10002001, 240, 521, 0.08%, Lemon, juice-babyfood-Cooked; Canned; Cook Meth N/S 6010430, 242, 121, 0.08%, Bean, snap, succulent-Cooked; Canned; Boiled10001990, 110, 560, 0.08%, Lemon-Uncooked; Fresh or N/S; Cook Meth N/S12000900, 211, 111, 0.08%, Cherry-Cooked; Fresh or N/S; Baked12000121, 240, 229, 0.07%, Apricot-babyfood-Cooked; Canned; Cook Meth N/S13021360, 110, 57, 0.07%, Currant-Uncooked; Fresh or N/S; Cook Meth N/S10002400, 110, 184, 0.07%, Orange-Uncooked; Fresh or N/S; Cook Meth N/S13020570, 120, 113, 0.06%, Blueberry-Uncooked; Frozen; Cook Meth N/S 9010750, 110, 227, 0.06%, Cantaloupe-Uncooked; Fresh or N/S; Cook Meth N/S 8003770, 240, 2309, 0.06%, Tomato, puree-Cooked; Canned; Cook Meth N/S12000141, 240, 105, 0.06%, Apricot, juice-babyfood-Cooked; Canned; Cook MethN/S

327

10002000, 211, 1109, 0.06%, Lemon, juice-Cooked; Fresh or N/S; Baked11002681, 240, 35, 0.06%, Pear, juice-babyfood-Cooked; Canned; Cook Meth N/S15004020, 232, 2965, 0.06%, Wheat, flour-Cooked; Dried; Boiled25002900, 211, 1105, 0.06%, Pork, meat-Cooked; Fresh or N/S; Baked11002660, 210, 295, 0.06%, Pear-Cooked; Fresh or N/S; Cook Meth N/S 8002730, 240, 1281, 0.06%, Pepper, nonbell, dried-Cooked; Canned; Cook MethN/S13013201, 240, 72, 0.06%, Raspberry-babyfood-Cooked; Canned; Cook Meth N/S25002900, 210, 2109, 0.05%, Pork, meat-Cooked; Fresh or N/S; Cook Meth N/S12000910, 120, 987, 0.05%, Cherry, juice-Uncooked; Frozen; Cook Meth N/S25002930, 230, 889, 0.05%, Pork, fat-Cooked; Dried; Cook Meth N/S 8002720, 221, 84, 0.05%, Pepper, nonbell-Cooked; Frozen; Baked95002360, 900, 1027, 0.05%, Olive, oil-Refined; FF N/A; Cook Meth N/S15001200, 230, 2396, 0.05%, Corn, field, flour-Cooked; Dried; Cook Meth N/S11000080, 211, 59, 0.05%, Apple, peeled fruit-Cooked; Fresh or N/S; Baked 8002720, 215, 504, 0.05%, Pepper, nonbell-Cooked; Fresh or N/S; Boiled/baked95001761, 240, 336, 0.05%, Grape, juice-babyfood-Cooked; Canned; Cook Meth N/S15001210, 233, 2187, 0.05%, Corn, field, meal-Cooked; Dried; Fried95003590, 240, 92, 0.05%, Strawberry-Cooked; Canned; Cook Meth N/S25002930, 240, 323, 0.04%, Pork, fat-Cooked; Canned; Cook Meth N/S13010550, 110, 33, 0.04%, Blackberry-Uncooked; Fresh or N/S; Cook Meth N/S 8003770, 210, 1470, 0.04%, Tomato, puree-Cooked; Fresh or N/S; Cook Meth N/S13010550, 211, 18, 0.04%, Blackberry-Cooked; Fresh or N/S; Baked21000440, 213, 2295, 0.04%, Beef, meat-Cooked; Fresh or N/S; Fried25002900, 213, 1662, 0.04%, Pork, meat-Cooked; Fresh or N/S; Fried10001070, 110, 61, 0.04%, Citrus hybrids-Uncooked; Fresh or N/S; Cook MethN/S 4012480, 210, 1302, 0.04%, Parsley, leaves-Cooked; Fresh or N/S; Cook Meth N/S15001240, 130, 1954, 0.04%, Corn, field, syrup-Uncooked; Dried; Cook Meth N/S13010561, 240, 32, 0.04%, Blackberry, juice-babyfood-Cooked; Canned; CookMeth N/S21000440, 211, 1543, 0.04%, Beef, meat-Cooked; Fresh or N/S; Baked15003250, 210, 737, 0.04%, Rice, flour-Cooked; Fresh or N/S; Cook Meth N/S13020570, 213, 42, 0.04%, Blueberry-Cooked; Fresh or N/S; Fried95000230, 110, 2513, 0.04%, Banana-Uncooked; Fresh or N/S; Cook Meth N/S27002220, 120, 2316, 0.03%, Milk, fat-Uncooked; Frozen; Cook Meth N/S11000100, 120, 214, 0.03%, Apple, juice-Uncooked; Frozen; Cook Meth N/S12000120, 240, 164, 0.03%, Apricot-Cooked; Canned; Cook Meth N/S 8002340, 212, 165, 0.03%, Okra-Cooked; Fresh or N/S; Boiled13020570, 240, 175, 0.03%, Blueberry-Cooked; Canned; Cook Meth N/S15004020, 210, 1934, 0.03%, Wheat, flour-Cooked; Fresh or N/S; Cook Meth N/S95001750, 240, 145, 0.03%, Grape-Cooked; Canned; Cook Meth N/S25002930, 212, 857, 0.03%, Pork, fat-Cooked; Fresh or N/S; Boiled13021370, 130, 19, 0.03%, Currant, dried-Uncooked; Dried; Cook Meth N/S21000470, 213, 2006, 0.03%, Beef, fat-Cooked; Fresh or N/S; Fried 6010430, 212, 50, 0.03%, Bean, snap, succulent-Cooked; Fresh or N/S; Boiled13013210, 240, 234, 0.03%, Raspberry, juice-Cooked; Canned; Cook Meth N/S 8002700, 213, 74, 0.03%, Pepper, bell-Cooked; Fresh or N/S; Fried95001760, 120, 144, 0.03%, Grape, juice-Uncooked; Frozen; Cook Meth N/S10002410, 240, 1470, 0.03%, Orange, juice-Cooked; Canned; Cook Meth N/S13013200, 211, 135, 0.03%, Raspberry-Cooked; Fresh or N/S; Baked 4011500, 110, 541, 0.03%, Endive-Uncooked; Fresh or N/S; Cook Meth N/S 8002720, 230, 120, 0.03%, Pepper, nonbell-Cooked; Dried; Cook Meth N/S12000901, 240, 39, 0.03%, Cherry-babyfood-Cooked; Canned; Cook Meth N/S15001210, 230, 1660, 0.03%, Corn, field, meal-Cooked; Dried; Cook Meth N/S12000130, 130, 93, 0.03%, Apricot, dried-Uncooked; Dried; Cook Meth N/S95003600, 210, 245, 0.03%, Strawberry, juice-Cooked; Fresh or N/S; Cook MethN/S13020570, 210, 33, 0.03%, Blueberry-Cooked; Fresh or N/S; Cook Meth N/S 9020210, 212, 38, 0.03%, Balsam pear-Cooked; Fresh or N/S; Boiled95002640, 210, 1798, 0.03%, Peanut, butter-Cooked; Fresh or N/S; Cook Meth N/S13013211, 240, 21, 0.02%, Raspberry, juice-babyfood-Cooked; Canned; Cook MethN/S27002220, 232, 1042, 0.02%, Milk, fat-Cooked; Dried; Boiled 8002340, 222, 19, 0.02%, Okra-Cooked; Frozen; Boiled

328

9021350, 110, 302, 0.02%, Cucumber-Uncooked; Fresh or N/S; Cook Meth N/S 6010431, 240, 34, 0.02%, Bean, snap, succulent-babyfood-Cooked; Canned; CookMeth N/S 8002700, 211, 142, 0.02%, Pepper, bell-Cooked; Fresh or N/S; Baked15001200, 214, 1121, 0.02%, Corn, field, flour-Cooked; Fresh or N/S;Fried/baked12002610, 230, 38, 0.02%, Peach, dried-Cooked; Dried; Cook Meth N/S12000120, 110, 36, 0.02%, Apricot-Uncooked; Fresh or N/S; Cook Meth N/S21000440, 212, 1106, 0.02%, Beef, meat-Cooked; Fresh or N/S; Boiled13021370, 230, 19, 0.02%, Currant, dried-Cooked; Dried; Cook Meth N/S95002790, 240, 582, 0.02%, Pineapple-Cooked; Canned; Cook Meth N/S12000900, 240, 134, 0.02%, Cherry-Cooked; Canned; Cook Meth N/S13013210, 120, 74, 0.02%, Raspberry, juice-Uncooked; Frozen; Cook Meth N/S10002060, 110, 81, 0.02%, Lime-Uncooked; Fresh or N/S; Cook Meth N/S15004020, 231, 1188, 0.02%, Wheat, flour-Cooked; Dried; Baked 8002340, 240, 22, 0.02%, Okra-Cooked; Canned; Cook Meth N/S 6003490, 210, 178, 0.02%, Soybean, soy milk-Cooked; Fresh or N/S; Cook MethN/S 8003760, 210, 1083, 0.02%, Tomato, paste-Cooked; Fresh or N/S; Cook Meth N/S12000140, 240, 121, 0.02%, Apricot, juice-Cooked; Canned; Cook Meth N/S20003651, 900, 901, 0.02%, Sunflower, oil-babyfood-Refined; FF N/A; Cook MethN/S 8002700, 215, 86, 0.02%, Pepper, bell-Cooked; Fresh or N/S; Boiled/baked 8003770, 212, 766, 0.02%, Tomato, puree-Cooked; Fresh or N/S; Boiled21000470, 211, 892, 0.02%, Beef, fat-Cooked; Fresh or N/S; Baked 1030821, 240, 650, 0.02%, Cassava-babyfood-Cooked; Canned; Cook Meth N/S25002930, 232, 333, 0.02%, Pork, fat-Cooked; Dried; Boiled 8002720, 211, 136, 0.02%, Pepper, nonbell-Cooked; Fresh or N/S; Baked 8003790, 240, 124, 0.02%, Tomato, juice-Cooked; Canned; Cook Meth N/S12002600, 211, 31, 0.02%, Peach-Cooked; Fresh or N/S; Baked10002000, 212, 72, 0.02%, Lemon, juice-Cooked; Fresh or N/S; Boiled 1033000, 212, 191, 0.01%, Potato, tuber, w/o peel-Cooked; Fresh or N/S;Boiled13010580, 210, 19, 0.01%, Boysenberry-Cooked; Fresh or N/S; Cook Meth N/S11002680, 240, 73, 0.01%, Pear, juice-Cooked; Canned; Cook Meth N/S 9021350, 240, 208, 0.01%, Cucumber-Cooked; Canned; Cook Meth N/S27002220, 211, 926, 0.01%, Milk, fat-Cooked; Fresh or N/S; Baked95001320, 240, 461, 0.01%, Cranberry, juice-Cooked; Canned; Cook Meth N/S15001260, 230, 804, 0.01%, Corn, pop-Cooked; Dried; Cook Meth N/S13010550, 120, 64, 0.01%, Blackberry-Uncooked; Frozen; Cook Meth N/S12002600, 120, 36, 0.01%, Peach-Uncooked; Frozen; Cook Meth N/S15001231, 240, 717, 0.01%, Corn, field, starch-babyfood-Cooked; Canned; CookMeth N/S21000470, 212, 783, 0.01%, Beef, fat-Cooked; Fresh or N/S; Boiled12000130, 211, 91, 0.01%, Apricot, dried-Cooked; Fresh or N/S; Baked 8003790, 212, 190, 0.01%, Tomato, juice-Cooked; Fresh or N/S; Boiled 6010430, 222, 20, 0.01%, Bean, snap, succulent-Cooked; Frozen; Boiled95003590, 120, 9, 0.01%, Strawberry-Uncooked; Frozen; Cook Meth N/S15004020, 213, 948, 0.01%, Wheat, flour-Cooked; Fresh or N/S; Fried21000441, 240, 458, 0.01%, Beef, meat-babyfood-Cooked; Canned; Cook Meth N/S12000900, 120, 39, 0.01%, Cherry-Uncooked; Frozen; Cook Meth N/S15004020, 212, 697, 0.01%, Wheat, flour-Cooked; Fresh or N/S; Boiled15001241, 240, 269, 0.01%, Corn, field, syrup-babyfood-Cooked; Canned; CookMeth N/S15001241, 230, 260, 0.01%, Corn, field, syrup-babyfood-Cooked; Dried; CookMeth N/S27002220, 215, 643, 0.01%, Milk, fat-Cooked; Fresh or N/S; Boiled/baked 8002730, 211, 178, 0.01%, Pepper, nonbell, dried-Cooked; Fresh or N/S; Baked 2001400, 212, 19, 0.01%, Dasheen, leaves-Cooked; Fresh or N/S; Boiled15001240, 120, 804, 0.01%, Corn, field, syrup-Uncooked; Frozen; Cook Meth N/S 8002720, 232, 185, 0.01%, Pepper, nonbell-Cooked; Dried; Boiled 8002730, 213, 458, 0.01%, Pepper, nonbell, dried-Cooked; Fresh or N/S; Fried 4013551, 240, 15, 0.01%, Spinach-babyfood-Cooked; Canned; Cook Meth N/S15001241, 130, 230, 0.01%, Corn, field, syrup-babyfood-Uncooked; Dried; CookMeth N/S

329

27002220, 210, 683, 0.01%, Milk, fat-Cooked; Fresh or N/S; Cook Meth N/S11000080, 240, 7, 0.01%, Apple, peeled fruit-Cooked; Canned; Cook Meth N/S12002850, 110, 46, 0.01%, Plum-Uncooked; Fresh or N/S; Cook Meth N/S 1010790, 240, 233, 0.01%, Carrot, juice-Cooked; Canned; Cook Meth N/S25002931, 240, 246, 0.01%, Pork, fat-babyfood-Cooked; Canned; Cook Meth N/S95003600, 110, 14, 0.01%, Strawberry, juice-Uncooked; Fresh or N/S; Cook MethN/S15004010, 211, 679, 0.01%, Wheat, grain-Cooked; Fresh or N/S; Baked 8002700, 222, 15, 0.01%, Pepper, bell-Cooked; Frozen; Boiled11000110, 210, 45, 0.01%, Apple, sauce-Cooked; Fresh or N/S; Cook Meth N/S15004020, 215, 563, 0.01%, Wheat, flour-Cooked; Fresh or N/S; Boiled/baked11000070, 211, 12, 0.01%, Apple, fruit with peel-Cooked; Fresh or N/S; Baked 1033661, 240, 165, 0.01%, Sweet potato-babyfood-Cooked; Canned; Cook Meth N/S 2001010, 110, 341, 0.01%, Chicory, tops-Uncooked; Fresh or N/S; Cook Meth N/S 9011870, 110, 42, 0.01%, Honeydew melon-Uncooked; Fresh or N/S; Cook MethN/S 8002730, 232, 342, 0.01%, Pepper, nonbell, dried-Cooked; Dried; Boiled95001760, 210, 281, 0.01%, Grape, juice-Cooked; Fresh or N/S; Cook Meth N/S12002851, 240, 26, 0.01%, Plum-babyfood-Cooked; Canned; Cook Meth N/S 8002700, 150, 55, 0.01%, Pepper, bell-Uncooked; Cured etc; Cook Meth N/S13020570, 230, 7, 0.01%, Blueberry-Cooked; Dried; Cook Meth N/S95002350, 210, 11, 0.01%, Olive-Cooked; Fresh or N/S; Cook Meth N/S95002350, 212, 2, 0.01%, Olive-Cooked; Fresh or N/S; Boiled 4012480, 110, 123, 0.01%, Parsley, leaves-Uncooked; Fresh or N/S; Cook MethN/S 6030420, 232, 434, 0.01%, Bean, pinto, seed-Cooked; Dried; Boiled15004020, 230, 420, 0.01%, Wheat, flour-Cooked; Dried; Cook Meth N/S11000070, 213, 4, 0.01%, Apple, fruit with peel-Cooked; Fresh or N/S; Fried27002220, 212, 424, 0.01%, Milk, fat-Cooked; Fresh or N/S; Boiled14000810, 211, 52, 0.01%, Cashew-Cooked; Fresh or N/S; Baked25002901, 240, 190, 0.01%, Pork, meat-babyfood-Cooked; Canned; Cook Meth N/S15001200, 210, 285, 0.01%, Corn, field, flour-Cooked; Fresh or N/S; Cook MethN/S25002900, 253, 264, 0.01%, Pork, meat-Cooked; Cured etc; Fried95003590, 211, 26, 0.01%, Strawberry-Cooked; Fresh or N/S; Baked21000470, 240, 325, 0.01%, Beef, fat-Cooked; Canned; Cook Meth N/S95002630, 211, 165, 0.01%, Peanut-Cooked; Fresh or N/S; Baked 9014000, 110, 57, 0.01%, Watermelon, juice-Uncooked; Fresh or N/S; Cook MethN/S10002000, 232, 70, 0.01%, Lemon, juice-Cooked; Dried; Boiled15001210, 232, 213, 0.01%, Corn, field, meal-Cooked; Dried; Boiled 1010790, 110, 70, 0.01%, Carrot, juice-Uncooked; Fresh or N/S; Cook Meth N/S25002900, 240, 203, 0.01%, Pork, meat-Cooked; Canned; Cook Meth N/S 8002700, 212, 32, 0.00%, Pepper, bell-Cooked; Fresh or N/S; Boiled14002820, 211, 126, 0.00%, Pistachio-Cooked; Fresh or N/S; Baked15001240, 211, 440, 0.00%, Corn, field, syrup-Cooked; Fresh or N/S; Baked 4012480, 212, 172, 0.00%, Parsley, leaves-Cooked; Fresh or N/S; Boiled 1034070, 110, 40, 0.00%, Yam bean-Uncooked; Fresh or N/S; Cook Meth N/S15004020, 240, 399, 0.00%, Wheat, flour-Cooked; Canned; Cook Meth N/S15004020, 214, 330, 0.00%, Wheat, flour-Cooked; Fresh or N/S; Fried/baked11002680, 110, 13, 0.00%, Pear, juice-Uncooked; Fresh or N/S; Cook Meth N/S 5010690, 110, 327, 0.00%, Cabbage-Uncooked; Fresh or N/S; Cook Meth N/S15001231, 130, 173, 0.00%, Corn, field, starch-babyfood-Uncooked; Dried; CookMeth N/S15004010, 230, 270, 0.00%, Wheat, grain-Cooked; Dried; Cook Meth N/S27002220, 213, 283, 0.00%, Milk, fat-Cooked; Fresh or N/S; Fried 8003760, 212, 256, 0.00%, Tomato, paste-Cooked; Fresh or N/S; Boiled15003250, 212, 38, 0.00%, Rice, flour-Cooked; Fresh or N/S; Boiled14002820, 110, 19, 0.00%, Pistachio-Uncooked; Fresh or N/S; Cook Meth N/S95000730, 110, 24, 0.00%, Cactus-Uncooked; Fresh or N/S; Cook Meth N/S12000120, 211, 2, 0.00%, Apricot-Cooked; Fresh or N/S; Baked25002900, 212, 147, 0.00%, Pork, meat-Cooked; Fresh or N/S; Boiled 4020860, 240, 55, 0.00%, Celery, juice-Cooked; Canned; Cook Meth N/S95000190, 212, 61, 0.00%, Asparagus-Cooked; Fresh or N/S; Boiled27022240, 110, 367, 0.00%, Milk, water-Uncooked; Fresh or N/S; Cook Meth N/S

330

15001240, 230, 160, 0.00%, Corn, field, syrup-Cooked; Dried; Cook Meth N/S15001240, 210, 226, 0.00%, Corn, field, syrup-Cooked; Fresh or N/S; Cook MethN/S15003240, 210, 66, 0.00%, Rice, brown-Cooked; Fresh or N/S; Cook Meth N/S15003240, 232, 144, 0.00%, Rice, brown-Cooked; Dried; Boiled 8002700, 221, 14, 0.00%, Pepper, bell-Cooked; Frozen; Baked 6030420, 230, 249, 0.00%, Bean, pinto, seed-Cooked; Dried; Cook Meth N/S21000460, 210, 152, 0.00%, Beef, meat byproducts-Cooked; Fresh or N/S; CookMeth N/S21000470, 250, 110, 0.00%, Beef, fat-Cooked; Cured etc; Cook Meth N/S15001210, 211, 241, 0.00%, Corn, field, meal-Cooked; Fresh or N/S; Baked27002220, 230, 139, 0.00%, Milk, fat-Cooked; Dried; Cook Meth N/S13021370, 211, 20, 0.00%, Currant, dried-Cooked; Fresh or N/S; Baked 4013550, 242, 8, 0.00%, Spinach-Cooked; Canned; Boiled19011440, 240, 164, 0.00%, Dillweed-Cooked; Canned; Cook Meth N/S21000440, 240, 234, 0.00%, Beef, meat-Cooked; Canned; Cook Meth N/S13010560, 110, 2, 0.00%, Blackberry, juice-Uncooked; Fresh or N/S; Cook MethN/S95002790, 110, 97, 0.00%, Pineapple-Uncooked; Fresh or N/S; Cook Meth N/S15003250, 120, 108, 0.00%, Rice, flour-Uncooked; Frozen; Cook Meth N/S15001260, 231, 75, 0.00%, Corn, pop-Cooked; Dried; Baked 9023080, 211, 105, 0.00%, Pumpkin-Cooked; Fresh or N/S; Baked12000140, 110, 1, 0.00%, Apricot, juice-Uncooked; Fresh or N/S; Cook MethN/S95001320, 110, 79, 0.00%, Cranberry, juice-Uncooked; Fresh or N/S; Cook MethN/S15001200, 213, 184, 0.00%, Corn, field, flour-Cooked; Fresh or N/S; Fried15001210, 231, 226, 0.00%, Corn, field, meal-Cooked; Dried; Baked 8003750, 110, 128, 0.00%, Tomato-Uncooked; Fresh or N/S; Cook Meth N/S12000120, 232, 3, 0.00%, Apricot-Cooked; Dried; Boiled12002861, 240, 8, 0.00%, Plum, prune, fresh-babyfood-Cooked; Canned; CookMeth N/S 8002340, 242, 19, 0.00%, Okra-Cooked; Canned; Boiled 9013990, 110, 82, 0.00%, Watermelon-Uncooked; Fresh or N/S; Cook Meth N/S11000100, 210, 155, 0.00%, Apple, juice-Cooked; Fresh or N/S; Cook Meth N/S 5010830, 212, 128, 0.00%, Cauliflower-Cooked; Fresh or N/S; Boiled 8001480, 214, 14, 0.00%, Eggplant-Cooked; Fresh or N/S; Fried/baked14003910, 211, 50, 0.00%, Walnut-Cooked; Fresh or N/S; Baked10002071, 240, 101, 0.00%, Lime, juice-babyfood-Cooked; Canned; Cook Meth N/S11000080, 110, 3, 0.00%, Apple, peeled fruit-Uncooked; Fresh or N/S; CookMeth N/S21000440, 214, 118, 0.00%, Beef, meat-Cooked; Fresh or N/S; Fried/baked15001201, 230, 120, 0.00%, Corn, field, flour-babyfood-Cooked; Dried; CookMeth N/S 1033660, 212, 51, 0.00%, Sweet potato-Cooked; Fresh or N/S; Boiled15001200, 211, 119, 0.00%, Corn, field, flour-Cooked; Fresh or N/S; Baked25002930, 221, 31, 0.00%, Pork, fat-Cooked; Frozen; Baked10002070, 250, 4, 0.00%, Lime, juice-Cooked; Cured etc; Cook Meth N/S20003640, 211, 41, 0.00%, Sunflower, seed-Cooked; Fresh or N/S; Baked 1033660, 211, 68, 0.00%, Sweet potato-Cooked; Fresh or N/S; Baked 1032990, 212, 39, 0.00%, Potato, tuber, w/peel-Cooked; Fresh or N/S; Boiled15003250, 211, 80, 0.00%, Rice, flour-Cooked; Fresh or N/S; Baked21000471, 240, 135, 0.00%, Beef,fat-babyfood-Cooked; Canned; Cook Meth N/S15001210, 210, 88, 0.00%, Corn, field, meal-Cooked; Fresh or N/S; Cook MethN/S25002930, 251, 61, 0.00%, Pork, fat-Cooked; Cured etc; Baked25002920, 210, 136, 0.00%, Pork, meat byproducts-Cooked; Fresh or N/S; CookMeth N/S10002010, 230, 117, 0.00%, Lemon, peel-Cooked; Dried; Cook Meth N/S 1033000, 211, 50, 0.00%, Potato, tuber, w/o peel-Cooked; Fresh or N/S; Baked12002600, 210, 6, 0.00%, Peach-Cooked; Fresh or N/S; Cook Meth N/S 6030420, 210, 79, 0.00%, Bean, pinto, seed-Cooked; Fresh or N/S; Cook MethN/S95000730, 210, 23, 0.00%, Cactus-Cooked; Fresh or N/S; Cook Meth N/S15003250, 232, 28, 0.00%, Rice, flour-Cooked; Dried; Boiled

331

13010560, 120, 1, 0.00%, Blackberry, juice-Uncooked; Frozen; Cook Meth N/S21000440, 250, 85, 0.00%, Beef, meat-Cooked; Cured etc; Cook Meth N/S25002930, 242, 61, 0.00%, Pork, fat-Cooked; Canned; Boiled 8003790, 110, 48, 0.00%, Tomato, juice-Uncooked; Fresh or N/S; Cook Meth N/S 8003750, 212, 80, 0.00%, Tomato-Cooked; Fresh or N/S; Boiled15001230, 210, 96, 0.00%, Corn, field, starch-Cooked; Fresh or N/S; Cook MethN/S15001240, 212, 104, 0.00%, Corn, field, syrup-Cooked; Fresh or N/S; Boiled 8003770, 211, 157, 0.00%, Tomato, puree-Cooked; Fresh or N/S; Baked10001990, 210, 23, 0.00%, Lemon-Cooked; Fresh or N/S; Cook Meth N/S11000080, 213, 4, 0.00%, Apple, peeled fruit-Cooked; Fresh or N/S; Fried 8002700, 240, 5, 0.00%, Pepper, bell-Cooked; Canned; Cook Meth N/S95000190, 242, 34, 0.00%, Asparagus-Cooked; Canned; Boiled23001690, 212, 46, 0.00%, Goat, meat-Cooked; Fresh or N/S; Boiled15001200, 231, 77, 0.00%, Corn, field, flour-Cooked; Dried; Baked25002900, 251, 57, 0.00%, Pork, meat-Cooked; Cured etc; Baked15004040, 230, 84, 0.00%, Wheat, bran-Cooked; Dried; Cook Meth N/S11000070, 150, 3, 0.00%, Apple, fruit with peel-Uncooked; Cured etc; CookMeth N/S 1030820, 210, 38, 0.00%, Cassava-Cooked; Fresh or N/S; Cook Meth N/S 8002700, 250, 4, 0.00%, Pepper, bell-Cooked; Cured etc; Cook Meth N/S26003390, 210, 27, 0.00%, Sheep, meat-Cooked; Fresh or N/S; Cook Meth N/S95002810, 211, 42, 0.00%, Pineapple, juice-Cooked; Fresh or N/S; Baked20003640, 230, 59, 0.00%, Sunflower, seed-Cooked; Dried; Cook Meth N/S 6030400, 232, 86, 0.00%, Bean, navy, seed-Cooked; Dried; Boiled 6030350, 232, 86, 0.00%, Bean, great northern, seed-Cooked; Dried; Boiled14003910, 130, 40, 0.00%, Walnut-Uncooked; Dried; Cook Meth N/S 8002721, 240, 26, 0.00%, Pepper, nonbell-babyfood-Cooked; Canned; Cook MethN/S10002411, 240, 43, 0.00%, Orange, juice-babyfood-Cooked; Canned; Cook MethN/S 9023090, 211, 39, 0.00%, Pumpkin, seed-Cooked; Fresh or N/S; Baked 8003740, 210, 83, 0.00%, Tomatillo-Cooked; Fresh or N/S; Cook Meth N/S 8002730, 215, 19, 0.00%, Pepper, nonbell, dried-Cooked; Fresh or N/S;Boiled/baked 8001480, 211, 3, 0.00%, Eggplant-Cooked; Fresh or N/S; Baked20003650, 900, 53, 0.00%, Sunflower, oil-Refined; FF N/A; Cook Meth N/S95003600, 120, 4, 0.00%, Strawberry, juice-Uncooked; Frozen; Cook Meth N/S20003640, 110, 52, 0.00%, Sunflower, seed-Uncooked; Fresh or N/S; Cook MethN/S 8003750, 215, 46, 0.00%, Tomato-Cooked; Fresh or N/S; Boiled/baked23001690, 211, 19, 0.00%, Goat, meat-Cooked; Fresh or N/S; Baked27002220, 214, 41, 0.00%, Milk, fat-Cooked; Fresh or N/S; Fried/baked 9023080, 215, 19, 0.00%, Pumpkin-Cooked; Fresh or N/S; Boiled/baked 8003750, 240, 39, 0.00%, Tomato-Cooked; Canned; Cook Meth N/S 1032990, 211, 27, 0.00%, Potato, tuber, w/peel-Cooked; Fresh or N/S; Baked10002070, 212, 9, 0.00%, Lime, juice-Cooked; Fresh or N/S; Boiled 6003481, 230, 77, 0.00%, Soybean, flour-babyfood-Cooked; Dried; Cook MethN/S 1033660, 210, 27, 0.00%, Sweet potato-Cooked; Fresh or N/S; Cook Meth N/S 6010430, 210, 1, 0.00%, Bean, snap, succulent-Cooked; Fresh or N/S; CookMeth N/S 8003770, 242, 22, 0.00%, Tomato, puree-Cooked; Canned; Boiled21000470, 215, 19, 0.00%, Beef, fat-Cooked; Fresh or N/S; Boiled/baked15001230, 110, 42, 0.00%, Corn, field, starch-Uncooked; Fresh or N/S; CookMeth N/S 8003740, 110, 19, 0.00%, Tomatillo-Uncooked; Fresh or N/S; Cook Meth N/S 1031390, 212, 20, 0.00%, Dasheen, corm-Cooked; Fresh or N/S; Boiled15004010, 232, 67, 0.00%, Wheat, grain-Cooked; Dried; Boiled 1013140, 110, 39, 0.00%, Radish, roots-Uncooked; Fresh or N/S; Cook Meth N/S11002680, 120, 22, 0.00%, Pear, juice-Uncooked; Frozen; Cook Meth N/S 8002700, 214, 2, 0.00%, Pepper, bell-Cooked; Fresh or N/S; Fried/baked15001210, 212, 60, 0.00%, Corn, field, meal-Cooked; Fresh or N/S; Boiled12002870, 130, 12, 0.00%, Plum, prune, dried-Uncooked; Dried; Cook Meth N/S 6032030, 232, 48, 0.00%, Lentil, seed-Cooked; Dried; Boiled

332

8003790, 210, 28, 0.00%, Tomato, juice-Cooked; Fresh or N/S; Cook Meth N/S 1010500, 250, 26, 0.00%, Beet, garden, roots-Cooked; Cured etc; Cook MethN/S 6010430, 240, 2, 0.00%, Bean, snap, succulent-Cooked; Canned; Cook Meth N/S 6003481, 240, 60, 0.00%, Soybean, flour-babyfood-Cooked; Canned; Cook MethN/S95002630, 210, 55, 0.00%, Peanut-Cooked; Fresh or N/S; Cook Meth N/S21000440, 215, 19, 0.00%, Beef, meat-Cooked; Fresh or N/S; Boiled/baked 1030820, 240, 20, 0.00%, Cassava-Cooked; Canned; Cook Meth N/S95001790, 110, 26, 0.00%, Grape, wine and sherry-Uncooked; Fresh or N/S; CookMeth N/S 8002730, 221, 20, 0.00%, Pepper, nonbell, dried-Cooked; Frozen; Baked15001230, 230, 42, 0.00%, Corn, field, starch-Cooked; Dried; Cook Meth N/S12000120, 213, 2, 0.00%, Apricot-Cooked; Fresh or N/S; Fried 9023571, 240, 44, 0.00%, Squash, winter-babyfood-Cooked; Canned; Cook MethN/S21000440, 221, 41, 0.00%, Beef, meat-Cooked; Frozen; Baked15004010, 231, 53, 0.00%, Wheat, grain-Cooked; Dried; Baked15001260, 211, 40, 0.00%, Corn, pop-Cooked; Fresh or N/S; Baked 6032560, 232, 18, 0.00%, Pea, dry-Cooked; Dried; Boiled26003410, 210, 22, 0.00%, Sheep, fat-Cooked; Fresh or N/S; Cook Meth N/S14002690, 211, 40, 0.00%, Pecan-Cooked; Fresh or N/S; Baked15004021, 211, 42, 0.00%, Wheat, flour-babyfood-Cooked; Fresh or N/S; Baked27002220, 242, 37, 0.00%, Milk, fat-Cooked; Canned; Boiled95001750, 120, 4, 0.00%, Grape-Uncooked; Frozen; Cook Meth N/S20003640, 210, 33, 0.00%, Sunflower, seed-Cooked; Fresh or N/S; Cook Meth N/S15001210, 215, 18, 0.00%, Corn, field, meal-Cooked; Fresh or N/S;Boiled/baked95003601, 240, 4, 0.00%, Strawberry, juice-babyfood-Cooked; Canned; CookMeth N/S15004011, 230, 19, 0.00%, Wheat, grain-babyfood-Cooked; Dried; Cook Meth N/S25002920, 232, 27, 0.00%, Pork, meat byproducts-Cooked; Dried; Boiled25002930, 222, 23, 0.00%, Pork, fat-Cooked; Frozen; Boiled95002791, 240, 26, 0.00%, Pineapple-babyfood-Cooked; Canned; Cook Meth N/S11000080, 221, 1, 0.00%, Apple, peeled fruit-Cooked; Frozen; Baked95002350, 221, 1, 0.00%, Olive-Cooked; Frozen; Baked25002900, 242, 23, 0.00%, Pork, meat-Cooked; Canned; Boiled11000110, 240, 6, 0.00%, Apple, sauce-Cooked; Canned; Cook Meth N/S25002950, 210, 20, 0.00%, Pork, liver-Cooked; Fresh or N/S; Cook Meth N/S95002640, 240, 36, 0.00%, Peanut, butter-Cooked; Canned; Cook Meth N/S21000470, 221, 22, 0.00%, Beef, fat-Cooked; Frozen; Baked 8002711, 240, 5, 0.00%, Pepper, bell, dried-babyfood-Cooked; Canned; CookMeth N/S 6030400, 212, 21, 0.00%, Bean, navy, seed-Cooked; Fresh or N/S; Boiled27002220, 221, 24, 0.00%, Milk, fat-Cooked; Frozen; Baked12000140, 120, 7, 0.00%, Apricot, juice-Uncooked; Frozen; Cook Meth N/S 6030340, 232, 21, 0.00%, Bean, cowpea, seed-Cooked; Dried; Boiled 5010830, 222, 23, 0.00%, Cauliflower-Cooked; Frozen; Boiled15004020, 233, 47, 0.00%, Wheat, flour-Cooked; Dried; Fried21000470, 253, 35, 0.00%, Beef, fat-Cooked; Cured etc; Fried 1010781, 240, 25, 0.00%, Carrot-babyfood-Cooked; Canned; Cook Meth N/S25002920, 250, 35, 0.00%, Pork, meat byproducts-Cooked; Cured etc; Cook MethN/S15001230, 232, 17, 0.00%, Corn, field, starch-Cooked; Dried; Boiled 1033000, 210, 13, 0.00%, Potato, tuber, w/o peel-Cooked; Fresh or N/S; CookMeth N/S95002350, 232, 1, 0.00%, Olive-Cooked; Dried; Boiled10002420, 210, 19, 0.00%, Orange, peel-Cooked; Fresh or N/S; Cook Meth N/S 6003490, 230, 3, 0.00%, Soybean, soy milk-Cooked; Dried; Cook Meth N/S10002420, 240, 20, 0.00%, Orange, peel-Cooked; Canned; Cook Meth N/S 9023560, 212, 17, 0.00%, Squash, summer-Cooked; Fresh or N/S; Boiled15004020, 221, 39, 0.00%, Wheat, flour-Cooked; Frozen; Baked 8003771, 240, 21, 0.00%, Tomato, puree-babyfood-Cooked; Canned; Cook MethN/S 8003750, 211, 20, 0.00%, Tomato-Cooked; Fresh or N/S; Baked

333

9021350, 150, 15, 0.00%, Cucumber-Uncooked; Cured etc; Cook Meth N/S 6030400, 210, 25, 0.00%, Bean, navy, seed-Cooked; Fresh or N/S; Cook MethN/S 6030350, 210, 25, 0.00%, Bean, great northern, seed-Cooked; Fresh or N/S;Cook Meth N/S15004010, 212, 19, 0.00%, Wheat, grain-Cooked; Fresh or N/S; Boiled 8003750, 210, 21, 0.00%, Tomato-Cooked; Fresh or N/S; Cook Meth N/S 6030390, 232, 18, 0.00%, Bean, mung, seed-Cooked; Dried; Boiled95002790, 211, 22, 0.00%, Pineapple-Cooked; Fresh or N/S; Baked15004021, 240, 34, 0.00%, Wheat, flour-babyfood-Cooked; Canned; Cook Meth N/S 8003770, 221, 22, 0.00%, Tomato, puree-Cooked; Frozen; Baked 8003760, 242, 16, 0.00%, Tomato, paste-Cooked; Canned; Boiled10001800, 110, 10, 0.00%, Grapefruit-Uncooked; Fresh or N/S; Cook Meth N/S 1033660, 242, 17, 0.00%, Sweet potato-Cooked; Canned; Boiled11000090, 210, 3, 0.00%, Apple, dried-Cooked; Fresh or N/S; Cook Meth N/S15001270, 222, 9, 0.00%, Corn, sweet-Cooked; Frozen; Boiled11000080, 210, 1, 0.00%, Apple, peeled fruit-Cooked; Fresh or N/S; Cook MethN/S15003240, 211, 7, 0.00%, Rice, brown-Cooked; Fresh or N/S; Baked 1013880, 212, 23, 0.00%, Turnip, roots-Cooked; Fresh or N/S; Boiled21000470, 214, 22, 0.00%, Beef, fat-Cooked; Fresh or N/S; Fried/baked 8003761, 240, 27, 0.00%, Tomato, paste-babyfood-Cooked; Canned; Cook MethN/S 1033000, 221, 13, 0.00%, Potato, tuber, w/o peel-Cooked; Frozen; Baked 1013140, 213, 19, 0.00%, Radish, roots-Cooked; Fresh or N/S; Fried25002900, 221, 19, 0.00%, Pork, meat-Cooked; Frozen; Baked19012490, 212, 23, 0.00%, Parsley, dried leaves-Cooked; Fresh or N/S; Boiled 9010750, 240, 2, 0.00%, Cantaloupe-Cooked; Canned; Cook Meth N/S 8001480, 210, 2, 0.00%, Eggplant-Cooked; Fresh or N/S; Cook Meth N/S 8003740, 240, 18, 0.00%, Tomatillo-Cooked; Canned; Cook Meth N/S95002350, 213, 1, 0.00%, Olive-Cooked; Fresh or N/S; Fried15001220, 230, 19, 0.00%, Corn, field, bran-Cooked; Dried; Cook Meth N/S 8003760, 211, 29, 0.00%, Tomato, paste-Cooked; Fresh or N/S; Baked15001270, 242, 7, 0.00%, Corn, sweet-Cooked; Canned; Boiled27002220, 220, 23, 0.00%, Milk, fat-Cooked; Frozen; Cook Meth N/S26003391, 240, 8, 0.00%, Sheep, meat-babyfood-Cooked; Canned; Cook Meth N/S15004021, 230, 15, 0.00%, Wheat, flour-babyfood-Cooked; Dried; Cook Meth N/S10002420, 212, 15, 0.00%, Orange, peel-Cooked; Fresh or N/S; Boiled10001060, 211, 4, 0.00%, Citrus citron-Cooked; Fresh or N/S; Baked 8002720, 250, 19, 0.00%, Pepper, nonbell-Cooked; Cured etc; Cook Meth N/S 8001480, 212, 8, 0.00%, Eggplant-Cooked; Fresh or N/S; Boiled11000110, 221, 1, 0.00%, Apple, sauce-Cooked; Frozen; Baked 8003760, 213, 17, 0.00%, Tomato, paste-Cooked; Fresh or N/S; Fried25002920, 213, 18, 0.00%, Pork, meat byproducts-Cooked; Fresh or N/S; Fried 5010690, 150, 19, 0.00%, Cabbage-Uncooked; Cured etc; Cook Meth N/S21000470, 232, 19, 0.00%, Beef, fat-Cooked; Dried; Boiled15001230, 120, 18, 0.00%, Corn, field, starch-Uncooked; Frozen; Cook Meth N/S15004011, 240, 15, 0.00%, Wheat, grain-babyfood-Cooked; Canned; Cook Meth N/S15001230, 240, 20, 0.00%, Corn, field, starch-Cooked; Canned; Cook Meth N/S10002010, 240, 19, 0.00%, Lemon, peel-Cooked; Canned; Cook Meth N/S95001780, 130, 7, 0.00%, Grape, raisin-Uncooked; Dried; Cook Meth N/S 6030420, 213, 14, 0.00%, Bean, pinto, seed-Cooked; Fresh or N/S; Fried 6030360, 212, 16, 0.00%, Bean, kidney, seed-Cooked; Fresh or N/S; Boiled15001230, 221, 14, 0.00%, Corn, field, starch-Cooked; Frozen; Baked 1010501, 240, 2, 0.00%, Beet, garden, roots-babyfood-Cooked; Canned; CookMeth N/S 6010430, 221, 1, 0.00%, Bean, snap, succulent-Cooked; Frozen; Baked95002630, 112, 6, 0.00%, Peanut-Uncooked; Fresh or N/S; Boiled 6010430, 213, 1, 0.00%, Bean, snap, succulent-Cooked; Fresh or N/S; Fried 1010500, 212, 6, 0.00%, Beet, garden, roots-Cooked; Fresh or N/S; Boiled 1010780, 212, 6, 0.00%, Carrot-Cooked; Fresh or N/S; Boiled14003910, 210, 9, 0.00%, Walnut-Cooked; Fresh or N/S; Cook Meth N/S14000810, 210, 9, 0.00%, Cashew-Cooked; Fresh or N/S; Cook Meth N/S 6003480, 210, 6, 0.00%, Soybean, flour-Cooked; Fresh or N/S; Cook Meth N/S27002220, 240, 4, 0.00%, Milk, fat-Cooked; Canned; Cook Meth N/S

334

8001480, 215, 2, 0.00%, Eggplant-Cooked; Fresh or N/S; Boiled/baked 6030360, 232, 7, 0.00%, Bean, kidney, seed-Cooked; Dried; Boiled15003230, 232, 7, 0.00%, Rice, white-Cooked; Dried; Boiled 5021170, 212, 4, 0.00%, Collards-Cooked; Fresh or N/S; Boiled15004010, 213, 6, 0.00%, Wheat, grain-Cooked; Fresh or N/S; Fried13010580, 130, 3, 0.00%, Boysenberry-Uncooked; Dried; Cook Meth N/S15001270, 212, 5, 0.00%, Corn, sweet-Cooked; Fresh or N/S; Boiled15001200, 232, 2, 0.00%, Corn, field, flour-Cooked; Dried; Boiled19012490, 232, 8, 0.00%, Parsley, dried leaves-Cooked; Dried; Boiled 1013160, 210, 2, 0.00%, Radish, Oriental, roots-Cooked; Fresh or N/S; CookMeth N/S 8002710, 213, 2, 0.00%, Pepper, bell, dried-Cooked; Fresh or N/S; Fried12002850, 240, 2, 0.00%, Plum-Cooked; Canned; Cook Meth N/S 1030820, 231, 2, 0.00%, Cassava-Cooked; Dried; Baked15001210, 213, 5, 0.00%, Corn, field, meal-Cooked; Fresh or N/S; Fried 1033001, 240, 3, 0.00%, Potato, tuber, w/o peel-babyfood-Cooked; Canned;Cook Meth N/S 1032980, 242, 2, 0.00%, Potato, flour-Cooked; Canned; Boiled11000110, 211, 2, 0.00%, Apple, sauce-Cooked; Fresh or N/S; Baked 1010780, 110, 3, 0.00%, Carrot-Uncooked; Fresh or N/S; Cook Meth N/S 8003770, 232, 2, 0.00%, Tomato, puree-Cooked; Dried; Boiled15003240, 212, 1, 0.00%, Rice, brown-Cooked; Fresh or N/S; Boiled 6003481, 130, 6, 0.00%, Soybean, flour-babyfood-Uncooked; Dried; Cook MethN/S 1032981, 240, 4, 0.00%, Potato, flour-babyfood-Cooked; Canned; Cook MethN/S 8003770, 215, 4, 0.00%, Tomato, puree-Cooked; Fresh or N/S; Boiled/baked 8001480, 213, 1, 0.00%, Eggplant-Cooked; Fresh or N/S; Fried 4012040, 110, 5, 0.00%, Lettuce, head-Uncooked; Fresh or N/S; Cook Meth N/S15003240, 215, 2, 0.00%, Rice, brown-Cooked; Fresh or N/S; Boiled/baked95000230, 240, 2, 0.00%, Banana-Cooked; Canned; Cook Meth N/S 4012480, 232, 2, 0.00%, Parsley, leaves-Cooked; Dried; Boiled 8002700, 242, 2, 0.00%, Pepper, bell-Cooked; Canned; Boiled15001241, 110, 4, 0.00%, Corn, field, syrup-babyfood-Uncooked; Fresh or N/S;Cook Meth N/S15001241, 210, 2, 0.00%, Corn, field, syrup-babyfood-Cooked; Fresh or N/S;Cook Meth N/S15001230, 130, 3, 0.00%, Corn, field, starch-Uncooked; Dried; Cook Meth N/S15001200, 212, 4, 0.00%, Corn, field, flour-Cooked; Fresh or N/S; Boiled 1033000, 242, 2, 0.00%, Potato, tuber, w/o peel-Cooked; Canned; Boiled 6030300, 232, 5, 0.00%, Bean, black, seed-Cooked; Dried; Boiled 9021020, 210, 1, 0.00%, Chinese waxgourd-Cooked; Fresh or N/S; Cook MethN/S 4012480, 211, 3, 0.00%, Parsley, leaves-Cooked; Fresh or N/S; Baked15001231, 110, 1, 0.00%, Corn, field, starch-babyfood-Uncooked; Fresh orN/S; Cook Meth N/S 1031390, 213, 1, 0.00%, Dasheen, corm-Cooked; Fresh or N/S; Fried 6030380, 232, 3, 0.00%, Bean, lima, seed-Cooked; Dried; Boiled21000450, 230, 4, 0.00%, Beef, meat, dried-Cooked; Dried; Cook Meth N/S 6003470, 232, 1, 0.00%, Soybean, seed-Cooked; Dried; Boiled15003250, 110, 2, 0.00%, Rice, flour-Uncooked; Fresh or N/S; Cook Meth N/S 8002700, 232, 1, 0.00%, Pepper, bell-Cooked; Dried; Boiled 9023080, 232, 2, 0.00%, Pumpkin-Cooked; Dried; Boiled10003700, 130, 3, 0.00%, Tangerine, juice-Uncooked; Dried; Cook Meth N/S 1010500, 242, 3, 0.00%, Beet, garden, roots-Cooked; Canned; Boiled26003390, 211, 3, 0.00%, Sheep, meat-Cooked; Fresh or N/S; Baked95002790, 210, 2, 0.00%, Pineapple-Cooked; Fresh or N/S; Cook Meth N/S19012490, 242, 3, 0.00%, Parsley, dried leaves-Cooked; Canned; Boiled15004010, 210, 4, 0.00%, Wheat, grain-Cooked; Fresh or N/S; Cook Meth N/S15003241, 240, 3, 0.00%, Rice, brown-babyfood-Cooked; Canned; Cook Meth N/S21000450, 232, 1, 0.00%, Beef, meat, dried-Cooked; Dried; Boiled21000460, 212, 2, 0.00%, Beef, meat byproducts-Cooked; Fresh or N/S; Boiled 8003750, 213, 2, 0.00%, Tomato-Cooked; Fresh or N/S; Fried95001300, 240, 2, 0.00%, Cranberry-Cooked; Canned; Cook Meth N/S 5010610, 222, 3, 0.00%, Broccoli-Cooked; Frozen; Boiled

335

8002720, 242, 1, 0.00%, Pepper, nonbell-Cooked; Canned; Boiled 1034060, 210, 1, 0.00%, Yam, true-Cooked; Fresh or N/S; Cook Meth N/S 6003470, 212, 2, 0.00%, Soybean, seed-Cooked; Fresh or N/S; Boiled11000101, 230, 1, 0.00%, Apple, juice-babyfood-Cooked; Dried; Cook Meth N/S15004010, 233, 3, 0.00%, Wheat, grain-Cooked; Dried; Fried 5023890, 242, 2, 0.00%, Turnip, greens-Cooked; Canned; Boiled15003240, 230, 2, 0.00%, Rice, brown-Cooked; Dried; Cook Meth N/S 5010610, 212, 3, 0.00%, Broccoli-Cooked; Fresh or N/S; Boiled 6003470, 240, 2, 0.00%, Soybean, seed-Cooked; Canned; Cook Meth N/S 8003790, 242, 3, 0.00%, Tomato, juice-Cooked; Canned; Boiled95002640, 211, 2, 0.00%, Peanut, butter-Cooked; Fresh or N/S; Baked27002221, 240, 3, 0.00%, Milk, fat - baby food/infant formula-Cooked;Canned; Cook Meth N/S 5010830, 110, 2, 0.00%, Cauliflower-Uncooked; Fresh or N/S; Cook Meth N/S 5023890, 212, 3, 0.00%, Turnip, greens-Cooked; Fresh or N/S; Boiled26003410, 211, 2, 0.00%, Sheep, fat-Cooked; Fresh or N/S; Baked12002860, 211, 2, 0.00%, Plum, prune, fresh-Cooked; Fresh or N/S; Baked10002070, 130, 2, 0.00%, Lime, juice-Uncooked; Dried; Cook Meth N/S10002070, 210, 2, 0.00%, Lime, juice-Cooked; Fresh or N/S; Cook Meth N/S 8003790, 211, 2, 0.00%, Tomato, juice-Cooked; Fresh or N/S; Baked25002930, 252, 1, 0.00%, Pork, fat-Cooked; Cured etc; Boiled12000910, 130, 2, 0.00%, Cherry, juice-Uncooked; Dried; Cook Meth N/S15001260, 210, 2, 0.00%, Corn, pop-Cooked; Fresh or N/S; Cook Meth N/S14000030, 230, 1, 0.00%, Almond-Cooked; Dried; Cook Meth N/S 1010780, 242, 2, 0.00%, Carrot-Cooked; Canned; Boiled15001230, 211, 2, 0.00%, Corn, field, starch-Cooked; Fresh or N/S; Baked25002930, 214, 1, 0.00%, Pork, fat-Cooked; Fresh or N/S; Fried/baked 6003481, 210, 2, 0.00%, Soybean, flour-babyfood-Cooked; Fresh or N/S; CookMeth N/S 1032980, 212, 1, 0.00%, Potato, flour-Cooked; Fresh or N/S; Boiled 6003470, 210, 1, 0.00%, Soybean, seed-Cooked; Fresh or N/S; Cook Meth N/S95000230, 212, 1, 0.00%, Banana-Cooked; Fresh or N/S; Boiled21000440, 253, 2, 0.00%, Beef, meat-Cooked; Cured etc; Fried10002000, 213, 1, 0.00%, Lemon, juice-Cooked; Fresh or N/S; Fried95000230, 120, 1, 0.00%, Banana-Uncooked; Frozen; Cook Meth N/S 4012480, 213, 1, 0.00%, Parsley, leaves-Cooked; Fresh or N/S; Fried 8003770, 213, 1, 0.00%, Tomato, puree-Cooked; Fresh or N/S; Fried25002900, 252, 1, 0.00%, Pork, meat-Cooked; Cured etc; Boiled 1032990, 213, 1, 0.00%, Potato, tuber, w/peel-Cooked; Fresh or N/S; Fried 9023560, 215, 1, 0.00%, Squash, summer-Cooked; Fresh or N/S; Boiled/baked 8002710, 110, 1, 0.00%, Pepper, bell, dried-Uncooked; Fresh or N/S; CookMeth N/S21000490, 210, 1, 0.00%, Beef, liver-Cooked; Fresh or N/S; Cook Meth N/S12002860, 232, 1, 0.00%, Plum, prune, fresh-Cooked; Dried; Boiled21000440, 242, 1, 0.00%, Beef, meat-Cooked; Canned; Boiled 4013550, 222, 1, 0.00%, Spinach-Cooked; Frozen; Boiled 6032560, 242, 1, 0.00%, Pea, dry-Cooked; Canned; Boiled15001241, 211, 1, 0.00%, Corn, field, syrup-babyfood-Cooked; Fresh or N/S;Baked95001321, 240, 1, 0.00%, Cranberry, juice-babyfood-Cooked; Canned; Cook MethN/S 6032030, 212, 1, 0.00%, Lentil, seed-Cooked; Fresh or N/S; Boiled19012490, 240, 1, 0.00%, Parsley, dried leaves-Cooked; Canned; Cook Meth N/S 6003480, 230, 1, 0.00%, Soybean, flour-Cooked; Dried; Cook Meth N/S25002920, 212, 1, 0.00%, Pork, meat byproducts-Cooked; Fresh or N/S; Boiled23001710, 212, 1, 0.00%, Goat, fat-Cooked; Fresh or N/S; Boiled 8002730, 230, 1, 0.00%, Pepper, nonbell, dried-Cooked; Dried; Cook Meth N/S95001320, 120, 1, 0.00%, Cranberry, juice-Uncooked; Frozen; Cook Meth N/S95001780, 230, 1, 0.00%, Grape, raisin-Cooked; Dried; Cook Meth N/S

336

Western regionLow percentile for CEC records: 95 Exposure (mg/day) = 0.000550High percentile for CEC records: 100 Exposure (mg/day) = 0.236331Number of actual records in this interval: 12480

Critical foods/foodforms for this population (as derived from these records): N=number of appearances in all records (including duplicates) %=percent of total exposure for all records (including duplicates)

Food, FF, N , Percent, Food Name --------, ---, -----, -------, -------------13021910, 110, 19, 6.24%, Huckleberry-Uncooked; Fresh or N/S; Cook Meth N/S12000910, 210, 1699, 5.21%, Cherry, juice-Cooked; Fresh or N/S; Cook Meth N/S95002810, 110, 1355, 5.08%, Pineapple, juice-Uncooked; Fresh or N/S; Cook MethN/S 8002720, 110, 1161, 4.81%, Pepper, nonbell-Uncooked; Fresh or N/S; Cook MethN/S10002000, 110, 1612, 4.49%, Lemon, juice-Uncooked; Fresh or N/S; Cook Meth N/S 5020700, 210, 554, 4.02%, Cabbage, Chinese, bok choy-Cooked; Fresh or N/S;Cook Meth N/S11000070, 110, 565, 3.07%, Apple, fruit with peel-Uncooked; Fresh or N/S; CookMeth N/S12002880, 110, 172, 2.82%, Plum, prune, juice-Uncooked; Fresh or N/S; CookMeth N/S 4023670, 212, 95, 2.66%, Swiss chard-Cooked; Fresh or N/S; Boiled12002620, 240, 172, 2.55%, Peach, juice-Cooked; Canned; Cook Meth N/S 4023220, 211, 171, 2.34%, Rhubarb-Cooked; Fresh or N/S; Baked 4023220, 240, 57, 2.31%, Rhubarb-Cooked; Canned; Cook Meth N/S 5022290, 212, 272, 2.17%, Mustard greens-Cooked; Fresh or N/S; Boiled 8002720, 212, 756, 2.14%, Pepper, nonbell-Cooked; Fresh or N/S; Boiled10003690, 110, 500, 1.97%, Tangerine-Uncooked; Fresh or N/S; Cook Meth N/S12002620, 110, 95, 1.96%, Peach, juice-Uncooked; Fresh or N/S; Cook Meth N/S 8002720, 210, 986, 1.89%, Pepper, nonbell-Cooked; Fresh or N/S; Cook Meth N/S12000910, 110, 174, 1.89%, Cherry, juice-Uncooked; Fresh or N/S; Cook Meth N/S 5020700, 150, 133, 1.62%, Cabbage, Chinese, bok choy-Uncooked; Cured etc;Cook Meth N/S95001750, 110, 178, 1.61%, Grape-Uncooked; Fresh or N/S; Cook Meth N/S10001810, 110, 639, 1.43%, Grapefruit, juice-Uncooked; Fresh or N/S; Cook MethN/S 8002720, 240, 710, 1.21%, Pepper, nonbell-Cooked; Canned; Cook Meth N/S10002000, 210, 1699, 1.18%, Lemon, juice-Cooked; Fresh or N/S; Cook Meth N/S12002610, 130, 193, 1.16%, Peach, dried-Uncooked; Dried; Cook Meth N/S 9010800, 110, 19, 1.07%, Casaba-Uncooked; Fresh or N/S; Cook Meth N/S11000100, 110, 1162, 1.01%, Apple, juice-Uncooked; Fresh or N/S; Cook Meth N/S 8002720, 213, 274, 0.97%, Pepper, nonbell-Cooked; Fresh or N/S; Fried13013200, 240, 169, 0.84%, Raspberry-Cooked; Canned; Cook Meth N/S 8002340, 210, 95, 0.82%, Okra-Cooked; Fresh or N/S; Cook Meth N/S 4020860, 110, 57, 0.80%, Celery, juice-Uncooked; Fresh or N/S; Cook Meth N/S95002350, 240, 64, 0.80%, Olive-Cooked; Canned; Cook Meth N/S12000911, 240, 171, 0.74%, Cherry, juice-babyfood-Cooked; Canned; Cook MethN/S11000090, 130, 250, 0.73%, Apple, dried-Uncooked; Dried; Cook Meth N/S10002070, 110, 250, 0.67%, Lime, juice-Uncooked; Fresh or N/S; Cook Meth N/S11002670, 130, 212, 0.66%, Pear, dried-Uncooked; Dried; Cook Meth N/S13020570, 110, 106, 0.66%, Blueberry-Uncooked; Fresh or N/S; Cook Meth N/S 9020880, 210, 136, 0.64%, Chayote, fruit-Cooked; Fresh or N/S; Cook Meth N/S13020570, 211, 84, 0.64%, Blueberry-Cooked; Fresh or N/S; Baked10001810, 120, 291, 0.61%, Grapefruit, juice-Uncooked; Frozen; Cook Meth N/S12002621, 240, 38, 0.55%, Peach, juice-babyfood-Cooked; Canned; Cook Meth N/S13010580, 240, 970, 0.55%, Boysenberry-Cooked; Canned; Cook Meth N/S10003700, 240, 1132, 0.54%, Tangerine, juice-Cooked; Canned; Cook Meth N/S13013200, 110, 93, 0.53%, Raspberry-Uncooked; Fresh or N/S; Cook Meth N/S10002000, 240, 1163, 0.48%, Lemon, juice-Cooked; Canned; Cook Meth N/S10002000, 130, 217, 0.47%, Lemon, juice-Uncooked; Dried; Cook Meth N/S

337

11002660, 110, 74, 0.46%, Pear-Uncooked; Fresh or N/S; Cook Meth N/S12002600, 240, 133, 0.43%, Peach-Cooked; Canned; Cook Meth N/S12002600, 110, 107, 0.42%, Peach-Uncooked; Fresh or N/S; Cook Meth N/S95002810, 120, 339, 0.38%, Pineapple, juice-Uncooked; Frozen; Cook Meth N/S10002070, 240, 997, 0.37%, Lime, juice-Cooked; Canned; Cook Meth N/S95002810, 240, 802, 0.36%, Pineapple, juice-Cooked; Canned; Cook Meth N/S10003700, 110, 174, 0.36%, Tangerine, juice-Uncooked; Fresh or N/S; Cook MethN/S27002220, 110, 3382, 0.36%, Milk, fat-Uncooked; Fresh or N/S; Cook Meth N/S25002930, 210, 1523, 0.36%, Pork, fat-Cooked; Fresh or N/S; Cook Meth N/S13013200, 120, 20, 0.35%, Raspberry-Uncooked; Frozen; Cook Meth N/S12002601, 240, 48, 0.31%, Peach-babyfood-Cooked; Canned; Cook Meth N/S 8002720, 220, 38, 0.30%, Pepper, nonbell-Cooked; Frozen; Cook Meth N/S95001760, 110, 533, 0.30%, Grape, juice-Uncooked; Fresh or N/S; Cook Meth N/S13010550, 240, 138, 0.30%, Blackberry-Cooked; Canned; Cook Meth N/S10002000, 120, 300, 0.29%, Lemon, juice-Uncooked; Frozen; Cook Meth N/S13021360, 110, 57, 0.28%, Currant-Uncooked; Fresh or N/S; Cook Meth N/S10001810, 240, 760, 0.28%, Grapefruit, juice-Cooked; Canned; Cook Meth N/S13013210, 110, 24, 0.25%, Raspberry, juice-Uncooked; Fresh or N/S; Cook MethN/S15003250, 230, 489, 0.22%, Rice, flour-Cooked; Dried; Cook Meth N/S 5022290, 222, 19, 0.21%, Mustard greens-Cooked; Frozen; Boiled13010580, 120, 244, 0.21%, Boysenberry-Uncooked; Frozen; Cook Meth N/S11000090, 211, 165, 0.21%, Apple, dried-Cooked; Fresh or N/S; Baked15001240, 240, 2293, 0.20%, Corn, field, syrup-Cooked; Canned; Cook Meth N/S15003251, 230, 270, 0.20%, Rice, flour-babyfood-Cooked; Dried; Cook Meth N/S10002410, 110, 1019, 0.19%, Orange, juice-Uncooked; Fresh or N/S; Cook Meth N/S11000110, 212, 180, 0.19%, Apple, sauce-Cooked; Fresh or N/S; Boiled25002930, 213, 680, 0.19%, Pork, fat-Cooked; Fresh or N/S; Fried13010580, 110, 98, 0.18%, Boysenberry-Uncooked; Fresh or N/S; Cook Meth N/S12002300, 110, 39, 0.18%, Nectarine-Uncooked; Fresh or N/S; Cook Meth N/S25002930, 250, 643, 0.18%, Pork, fat-Cooked; Cured etc; Cook Meth N/S 8002340, 220, 38, 0.17%, Okra-Cooked; Frozen; Cook Meth N/S12000910, 240, 561, 0.17%, Cherry, juice-Cooked; Canned; Cook Meth N/S11000081, 240, 28, 0.17%, Apple, peeled fruit-babyfood-Cooked; Canned; CookMeth N/S 8002720, 215, 261, 0.16%, Pepper, nonbell-Cooked; Fresh or N/S; Boiled/baked12000900, 110, 70, 0.16%, Cherry-Uncooked; Fresh or N/S; Cook Meth N/S11002660, 240, 33, 0.16%, Pear-Cooked; Canned; Cook Meth N/S13020571, 240, 19, 0.14%, Blueberry-babyfood-Cooked; Canned; Cook Meth N/S13020570, 120, 23, 0.14%, Blueberry-Uncooked; Frozen; Cook Meth N/S25002930, 211, 610, 0.14%, Pork, fat-Cooked; Fresh or N/S; Baked95002800, 130, 193, 0.14%, Pineapple, dried-Uncooked; Dried; Cook Meth N/S 8002730, 210, 284, 0.13%, Pepper, nonbell, dried-Cooked; Fresh or N/S; CookMeth N/S 8002720, 221, 41, 0.13%, Pepper, nonbell-Cooked; Frozen; Baked15004020, 211, 1726, 0.13%, Wheat, flour-Cooked; Fresh or N/S; Baked13021370, 130, 19, 0.12%, Currant, dried-Uncooked; Dried; Cook Meth N/S11000111, 240, 105, 0.12%, Apple, sauce-babyfood-Cooked; Canned; Cook Meth N/S 8002700, 110, 78, 0.12%, Pepper, bell-Uncooked; Fresh or N/S; Cook Meth N/S11000101, 240, 208, 0.11%, Apple, juice-babyfood-Cooked; Canned; Cook Meth N/S11002661, 240, 16, 0.11%, Pear-babyfood-Cooked; Canned; Cook Meth N/S10002410, 120, 595, 0.11%, Orange, juice-Uncooked; Frozen; Cook Meth N/S95002350, 211, 25, 0.11%, Olive-Cooked; Fresh or N/S; Baked25002930, 230, 421, 0.10%, Pork, fat-Cooked; Dried; Cook Meth N/S 9020210, 212, 38, 0.10%, Balsam pear-Cooked; Fresh or N/S; Boiled 8002720, 150, 58, 0.10%, Pepper, nonbell-Uncooked; Cured etc; Cook Meth N/S13020570, 214, 16, 0.10%, Blueberry-Cooked; Fresh or N/S; Fried/baked 8002700, 210, 58, 0.09%, Pepper, bell-Cooked; Fresh or N/S; Cook Meth N/S95003590, 110, 35, 0.09%, Strawberry-Uncooked; Fresh or N/S; Cook Meth N/S95003600, 240, 39, 0.09%, Strawberry, juice-Cooked; Canned; Cook Meth N/S95002811, 240, 78, 0.09%, Pineapple, juice-babyfood-Cooked; Canned; Cook MethN/S95001750, 210, 81, 0.09%, Grape-Cooked; Fresh or N/S; Cook Meth N/S 8002730, 212, 249, 0.09%, Pepper, nonbell, dried-Cooked; Fresh or N/S; Boiled

338

10002400, 110, 47, 0.08%, Orange-Uncooked; Fresh or N/S; Cook Meth N/S15001240, 110, 1005, 0.08%, Corn, field, syrup-Uncooked; Fresh or N/S; CookMeth N/S10003700, 120, 224, 0.08%, Tangerine, juice-Uncooked; Frozen; Cook Meth N/S95001760, 240, 300, 0.08%, Grape, juice-Cooked; Canned; Cook Meth N/S10001990, 110, 186, 0.08%, Lemon-Uncooked; Fresh or N/S; Cook Meth N/S21000470, 210, 713, 0.07%, Beef, fat-Cooked; Fresh or N/S; Cook Meth N/S10002070, 120, 271, 0.07%, Lime, juice-Uncooked; Frozen; Cook Meth N/S 5020700, 110, 19, 0.07%, Cabbage, Chinese, bok choy-Uncooked; Fresh or N/S;Cook Meth N/S12002610, 230, 19, 0.07%, Peach, dried-Cooked; Dried; Cook Meth N/S10002000, 211, 346, 0.07%, Lemon, juice-Cooked; Fresh or N/S; Baked11000100, 120, 59, 0.06%, Apple, juice-Uncooked; Frozen; Cook Meth N/S 8002340, 213, 19, 0.06%, Okra-Cooked; Fresh or N/S; Fried 8002720, 230, 78, 0.06%, Pepper, nonbell-Cooked; Dried; Cook Meth N/S21000440, 210, 684, 0.06%, Beef, meat-Cooked; Fresh or N/S; Cook Meth N/S12000900, 211, 13, 0.06%, Cherry-Cooked; Fresh or N/S; Baked12000141, 240, 8, 0.06%, Apricot, juice-babyfood-Cooked; Canned; Cook MethN/S13010580, 210, 19, 0.06%, Boysenberry-Cooked; Fresh or N/S; Cook Meth N/S12000140, 240, 36, 0.06%, Apricot, juice-Cooked; Canned; Cook Meth N/S 8002730, 240, 299, 0.05%, Pepper, nonbell, dried-Cooked; Canned; Cook MethN/S25002900, 211, 206, 0.05%, Pork, meat-Cooked; Fresh or N/S; Baked25002900, 250, 459, 0.05%, Pork, meat-Cooked; Cured etc; Cook Meth N/S15001200, 214, 602, 0.05%, Corn, field, flour-Cooked; Fresh or N/S;Fried/baked11002660, 210, 59, 0.05%, Pear-Cooked; Fresh or N/S; Cook Meth N/S 6010430, 242, 16, 0.05%, Bean, snap, succulent-Cooked; Canned; Boiled12000910, 120, 220, 0.05%, Cherry, juice-Uncooked; Frozen; Cook Meth N/S 8002720, 211, 78, 0.05%, Pepper, nonbell-Cooked; Fresh or N/S; Baked15001210, 233, 462, 0.05%, Corn, field, meal-Cooked; Dried; Fried13013201, 240, 16, 0.05%, Raspberry-babyfood-Cooked; Canned; Cook Meth N/S 8003790, 240, 46, 0.05%, Tomato, juice-Cooked; Canned; Cook Meth N/S11000091, 230, 21, 0.05%, Apple, dried-babyfood-Cooked; Dried; Cook Meth N/S12000120, 110, 25, 0.05%, Apricot-Uncooked; Fresh or N/S; Cook Meth N/S95003590, 240, 24, 0.05%, Strawberry-Cooked; Canned; Cook Meth N/S 9010750, 110, 45, 0.04%, Cantaloupe-Uncooked; Fresh or N/S; Cook Meth N/S95001760, 120, 58, 0.04%, Grape, juice-Uncooked; Frozen; Cook Meth N/S15003251, 240, 145, 0.04%, Rice, flour-babyfood-Cooked; Canned; Cook Meth N/S25002900, 210, 381, 0.04%, Pork, meat-Cooked; Fresh or N/S; Cook Meth N/S25002930, 253, 189, 0.04%, Pork, fat-Cooked; Cured etc; Fried12000120, 240, 47, 0.04%, Apricot-Cooked; Canned; Cook Meth N/S 8002700, 215, 45, 0.04%, Pepper, bell-Cooked; Fresh or N/S; Boiled/baked95002360, 900, 164, 0.04%, Olive, oil-Refined; FF N/A; Cook Meth N/S13013200, 211, 28, 0.04%, Raspberry-Cooked; Fresh or N/S; Baked12000130, 130, 51, 0.04%, Apricot, dried-Uncooked; Dried; Cook Meth N/S 8002700, 213, 16, 0.03%, Pepper, bell-Cooked; Fresh or N/S; Fried13013211, 240, 6, 0.03%, Raspberry, juice-babyfood-Cooked; Canned; Cook MethN/S13010550, 211, 5, 0.03%, Blackberry-Cooked; Fresh or N/S; Baked11000090, 230, 56, 0.03%, Apple, dried-Cooked; Dried; Cook Meth N/S95001750, 240, 42, 0.03%, Grape-Cooked; Canned; Cook Meth N/S13010550, 110, 12, 0.03%, Blackberry-Uncooked; Fresh or N/S; Cook Meth N/S95000230, 110, 499, 0.03%, Banana-Uncooked; Fresh or N/S; Cook Meth N/S13010561, 240, 7, 0.03%, Blackberry, juice-babyfood-Cooked; Canned; CookMeth N/S12000121, 240, 29, 0.03%, Apricot-babyfood-Cooked; Canned; Cook Meth N/S21000440, 213, 383, 0.03%, Beef, meat-Cooked; Fresh or N/S; Fried21000440, 212, 341, 0.03%, Beef, meat-Cooked; Fresh or N/S; Boiled95003600, 210, 47, 0.03%, Strawberry, juice-Cooked; Fresh or N/S; Cook MethN/S11000100, 240, 107, 0.03%, Apple, juice-Cooked; Canned; Cook Meth N/S25002930, 212, 166, 0.03%, Pork, fat-Cooked; Fresh or N/S; Boiled 4011500, 110, 146, 0.03%, Endive-Uncooked; Fresh or N/S; Cook Meth N/S

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15001200, 230, 351, 0.03%, Corn, field, flour-Cooked; Dried; Cook Meth N/S 8003770, 210, 294, 0.03%, Tomato, puree-Cooked; Fresh or N/S; Cook Meth N/S95001761, 240, 50, 0.03%, Grape, juice-babyfood-Cooked; Canned; Cook Meth N/S11002681, 240, 7, 0.03%, Pear, juice-babyfood-Cooked; Canned; Cook Meth N/S25002900, 213, 267, 0.03%, Pork, meat-Cooked; Fresh or N/S; Fried 8003770, 240, 212, 0.03%, Tomato, puree-Cooked; Canned; Cook Meth N/S15004020, 210, 325, 0.03%, Wheat, flour-Cooked; Fresh or N/S; Cook Meth N/S12000900, 120, 10, 0.03%, Cherry-Uncooked; Frozen; Cook Meth N/S 4012480, 210, 138, 0.02%, Parsley, leaves-Cooked; Fresh or N/S; Cook Meth N/S10002001, 240, 39, 0.02%, Lemon, juice-babyfood-Cooked; Canned; Cook Meth N/S15004020, 232, 330, 0.02%, Wheat, flour-Cooked; Dried; Boiled13020570, 213, 12, 0.02%, Blueberry-Cooked; Fresh or N/S; Fried95002350, 212, 1, 0.02%, Olive-Cooked; Fresh or N/S; Boiled 9021350, 110, 65, 0.02%, Cucumber-Uncooked; Fresh or N/S; Cook Meth N/S25002930, 232, 100, 0.02%, Pork, fat-Cooked; Dried; Boiled15001240, 130, 218, 0.02%, Corn, field, syrup-Uncooked; Dried; Cook Meth N/S 8002730, 211, 43, 0.02%, Pepper, nonbell, dried-Cooked; Fresh or N/S; Baked13020570, 240, 34, 0.02%, Blueberry-Cooked; Canned; Cook Meth N/S 8003770, 212, 202, 0.02%, Tomato, puree-Cooked; Fresh or N/S; Boiled 8002700, 211, 34, 0.02%, Pepper, bell-Cooked; Fresh or N/S; Baked 4013551, 240, 4, 0.02%, Spinach-babyfood-Cooked; Canned; Cook Meth N/S11000080, 211, 5, 0.02%, Apple, peeled fruit-Cooked; Fresh or N/S; Baked10002060, 110, 58, 0.02%, Lime-Uncooked; Fresh or N/S; Cook Meth N/S15001241, 130, 74, 0.02%, Corn, field, syrup-babyfood-Uncooked; Dried; CookMeth N/S21000440, 211, 188, 0.02%, Beef, meat-Cooked; Fresh or N/S; Baked27002220, 120, 277, 0.02%, Milk, fat-Uncooked; Frozen; Cook Meth N/S25002930, 240, 32, 0.02%, Pork, fat-Cooked; Canned; Cook Meth N/S 1010790, 240, 99, 0.02%, Carrot, juice-Cooked; Canned; Cook Meth N/S 1034070, 110, 40, 0.02%, Yam bean-Uncooked; Fresh or N/S; Cook Meth N/S13013210, 240, 39, 0.02%, Raspberry, juice-Cooked; Canned; Cook Meth N/S 8003790, 212, 48, 0.02%, Tomato, juice-Cooked; Fresh or N/S; Boiled15003250, 210, 72, 0.02%, Rice, flour-Cooked; Fresh or N/S; Cook Meth N/S15001210, 230, 298, 0.02%, Corn, field, meal-Cooked; Dried; Cook Meth N/S 9011870, 110, 4, 0.02%, Honeydew melon-Uncooked; Fresh or N/S; Cook MethN/S95003600, 110, 7, 0.02%, Strawberry, juice-Uncooked; Fresh or N/S; Cook MethN/S20003651, 900, 151, 0.02%, Sunflower, oil-babyfood-Refined; FF N/A; Cook MethN/S 9021350, 240, 33, 0.01%, Cucumber-Cooked; Canned; Cook Meth N/S21000470, 213, 266, 0.01%, Beef, fat-Cooked; Fresh or N/S; Fried15004020, 231, 161, 0.01%, Wheat, flour-Cooked; Dried; Baked10002000, 232, 25, 0.01%, Lemon, juice-Cooked; Dried; Boiled 9014000, 110, 19, 0.01%, Watermelon, juice-Uncooked; Fresh or N/S; Cook MethN/S21000470, 212, 162, 0.01%, Beef, fat-Cooked; Fresh or N/S; Boiled95002640, 210, 210, 0.01%, Peanut, butter-Cooked; Fresh or N/S; Cook Meth N/S 1010790, 110, 39, 0.01%, Carrot, juice-Uncooked; Fresh or N/S; Cook Meth N/S21000441, 240, 53, 0.01%, Beef, meat-babyfood-Cooked; Canned; Cook Meth N/S 4020860, 240, 22, 0.01%, Celery, juice-Cooked; Canned; Cook Meth N/S11000080, 240, 2, 0.01%, Apple, peeled fruit-Cooked; Canned; Cook Meth N/S15003250, 212, 21, 0.01%, Rice, flour-Cooked; Fresh or N/S; Boiled 6010431, 240, 2, 0.01%, Bean, snap, succulent-babyfood-Cooked; Canned; CookMeth N/S 8003760, 210, 129, 0.01%, Tomato, paste-Cooked; Fresh or N/S; Cook Meth N/S15001241, 230, 56, 0.01%, Corn, field, syrup-babyfood-Cooked; Dried; CookMeth N/S15001241, 240, 45, 0.01%, Corn, field, syrup-babyfood-Cooked; Canned; CookMeth N/S12000900, 240, 20, 0.01%, Cherry-Cooked; Canned; Cook Meth N/S15004010, 211, 160, 0.01%, Wheat, grain-Cooked; Fresh or N/S; Baked 4012480, 110, 40, 0.01%, Parsley, leaves-Uncooked; Fresh or N/S; Cook MethN/S12000120, 211, 1, 0.01%, Apricot-Cooked; Fresh or N/S; Baked

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6010430, 212, 4, 0.01%, Bean, snap, succulent-Cooked; Fresh or N/S; Boiled95002790, 240, 68, 0.01%, Pineapple-Cooked; Canned; Cook Meth N/S21000470, 211, 98, 0.01%, Beef, fat-Cooked; Fresh or N/S; Baked27002220, 232, 144, 0.01%, Milk, fat-Cooked; Dried; Boiled15001260, 230, 115, 0.01%, Corn, pop-Cooked; Dried; Cook Meth N/S12000130, 211, 3, 0.01%, Apricot, dried-Cooked; Fresh or N/S; Baked 1033000, 212, 42, 0.01%, Potato, tuber, w/o peel-Cooked; Fresh or N/S;Boiled 8002720, 232, 79, 0.01%, Pepper, nonbell-Cooked; Dried; Boiled15004020, 212, 100, 0.01%, Wheat, flour-Cooked; Fresh or N/S; Boiled95003590, 211, 6, 0.01%, Strawberry-Cooked; Fresh or N/S; Baked 1030821, 240, 94, 0.01%, Cassava-babyfood-Cooked; Canned; Cook Meth N/S 6003490, 210, 50, 0.01%, Soybean, soy milk-Cooked; Fresh or N/S; Cook MethN/S 2001010, 110, 94, 0.01%, Chicory, tops-Uncooked; Fresh or N/S; Cook Meth N/S 6010430, 222, 2, 0.01%, Bean, snap, succulent-Cooked; Frozen; Boiled 8002700, 212, 10, 0.01%, Pepper, bell-Cooked; Fresh or N/S; Boiled14003910, 211, 22, 0.01%, Walnut-Cooked; Fresh or N/S; Baked27002220, 211, 108, 0.01%, Milk, fat-Cooked; Fresh or N/S; Baked13020570, 210, 3, 0.01%, Blueberry-Cooked; Fresh or N/S; Cook Meth N/S15001200, 210, 91, 0.01%, Corn, field, flour-Cooked; Fresh or N/S; Cook MethN/S27002220, 210, 138, 0.01%, Milk, fat-Cooked; Fresh or N/S; Cook Meth N/S13010560, 120, 1, 0.01%, Blackberry, juice-Uncooked; Frozen; Cook Meth N/S21000470, 250, 40, 0.01%, Beef, fat-Cooked; Cured etc; Cook Meth N/S95001760, 210, 55, 0.01%, Grape, juice-Cooked; Fresh or N/S; Cook Meth N/S15001240, 120, 70, 0.01%, Corn, field, syrup-Uncooked; Frozen; Cook Meth N/S15001200, 211, 74, 0.01%, Corn, field, flour-Cooked; Fresh or N/S; Baked12002850, 110, 9, 0.01%, Plum-Uncooked; Fresh or N/S; Cook Meth N/S13013210, 120, 16, 0.01%, Raspberry, juice-Uncooked; Frozen; Cook Meth N/S12000901, 240, 2, 0.01%, Cherry-babyfood-Cooked; Canned; Cook Meth N/S15003250, 120, 39, 0.01%, Rice, flour-Uncooked; Frozen; Cook Meth N/S 8002700, 150, 7, 0.01%, Pepper, bell-Uncooked; Cured etc; Cook Meth N/S 6030420, 232, 94, 0.01%, Bean, pinto, seed-Cooked; Dried; Boiled12002600, 211, 2, 0.01%, Peach-Cooked; Fresh or N/S; Baked15001231, 130, 57, 0.01%, Corn, field, starch-babyfood-Uncooked; Dried; CookMeth N/S10002410, 240, 51, 0.01%, Orange, juice-Cooked; Canned; Cook Meth N/S15004020, 213, 103, 0.00%, Wheat, flour-Cooked; Fresh or N/S; Fried11000110, 210, 19, 0.00%, Apple, sauce-Cooked; Fresh or N/S; Cook Meth N/S15004020, 230, 86, 0.00%, Wheat, flour-Cooked; Dried; Cook Meth N/S15001231, 240, 66, 0.00%, Corn, field, starch-babyfood-Cooked; Canned; CookMeth N/S13010550, 120, 15, 0.00%, Blackberry-Uncooked; Frozen; Cook Meth N/S10002070, 250, 2, 0.00%, Lime, juice-Cooked; Cured etc; Cook Meth N/S 8002730, 215, 19, 0.00%, Pepper, nonbell, dried-Cooked; Fresh or N/S;Boiled/baked95001320, 240, 29, 0.00%, Cranberry, juice-Cooked; Canned; Cook Meth N/S 6030420, 230, 64, 0.00%, Bean, pinto, seed-Cooked; Dried; Cook Meth N/S 4012480, 212, 56, 0.00%, Parsley, leaves-Cooked; Fresh or N/S; Boiled15003250, 232, 22, 0.00%, Rice, flour-Cooked; Dried; Boiled15004020, 214, 69, 0.00%, Wheat, flour-Cooked; Fresh or N/S; Fried/baked11002680, 240, 11, 0.00%, Pear, juice-Cooked; Canned; Cook Meth N/S15004020, 240, 57, 0.00%, Wheat, flour-Cooked; Canned; Cook Meth N/S 8002700, 250, 2, 0.00%, Pepper, bell-Cooked; Cured etc; Cook Meth N/S95003600, 120, 3, 0.00%, Strawberry, juice-Uncooked; Frozen; Cook Meth N/S27002220, 215, 51, 0.00%, Milk, fat-Cooked; Fresh or N/S; Boiled/baked21000471, 240, 40, 0.00%, Beef,fat-babyfood-Cooked; Canned; Cook Meth N/S 8002730, 213, 59, 0.00%, Pepper, nonbell, dried-Cooked; Fresh or N/S; Fried 8003750, 110, 23, 0.00%, Tomato-Uncooked; Fresh or N/S; Cook Meth N/S21000440, 250, 38, 0.00%, Beef, meat-Cooked; Cured etc; Cook Meth N/S15001210, 231, 40, 0.00%, Corn, field, meal-Cooked; Dried; Baked21000470, 215, 19, 0.00%, Beef, fat-Cooked; Fresh or N/S; Boiled/baked10001070, 110, 2, 0.00%, Citrus hybrids-Uncooked; Fresh or N/S; Cook MethN/S

341

8003740, 110, 19, 0.00%, Tomatillo-Uncooked; Fresh or N/S; Cook Meth N/S12002851, 240, 1, 0.00%, Plum-babyfood-Cooked; Canned; Cook Meth N/S20003640, 211, 19, 0.00%, Sunflower, seed-Cooked; Fresh or N/S; Baked25002900, 212, 37, 0.00%, Pork, meat-Cooked; Fresh or N/S; Boiled 1033660, 212, 12, 0.00%, Sweet potato-Cooked; Fresh or N/S; Boiled13020570, 230, 1, 0.00%, Blueberry-Cooked; Dried; Cook Meth N/S15003250, 211, 20, 0.00%, Rice, flour-Cooked; Fresh or N/S; Baked 8002340, 150, 1, 0.00%, Okra-Uncooked; Cured etc; Cook Meth N/S95002790, 110, 6, 0.00%, Pineapple-Uncooked; Fresh or N/S; Cook Meth N/S27002220, 212, 38, 0.00%, Milk, fat-Cooked; Fresh or N/S; Boiled 5010690, 110, 40, 0.00%, Cabbage-Uncooked; Fresh or N/S; Cook Meth N/S 8002700, 240, 1, 0.00%, Pepper, bell-Cooked; Canned; Cook Meth N/S15003240, 232, 40, 0.00%, Rice, brown-Cooked; Dried; Boiled95001320, 110, 6, 0.00%, Cranberry, juice-Uncooked; Fresh or N/S; Cook MethN/S21000440, 215, 19, 0.00%, Beef, meat-Cooked; Fresh or N/S; Boiled/baked11000100, 210, 31, 0.00%, Apple, juice-Cooked; Fresh or N/S; Cook Meth N/S19011440, 240, 41, 0.00%, Dillweed-Cooked; Canned; Cook Meth N/S10002071, 240, 21, 0.00%, Lime, juice-babyfood-Cooked; Canned; Cook Meth N/S12002861, 240, 1, 0.00%, Plum, prune, fresh-babyfood-Cooked; Canned; CookMeth N/S 8002730, 232, 31, 0.00%, Pepper, nonbell, dried-Cooked; Dried; Boiled15004020, 215, 34, 0.00%, Wheat, flour-Cooked; Fresh or N/S; Boiled/baked 1031390, 212, 19, 0.00%, Dasheen, corm-Cooked; Fresh or N/S; Boiled 8003750, 215, 21, 0.00%, Tomato-Cooked; Fresh or N/S; Boiled/baked 1030820, 210, 19, 0.00%, Cassava-Cooked; Fresh or N/S; Cook Meth N/S 9013990, 110, 18, 0.00%, Watermelon-Uncooked; Fresh or N/S; Cook Meth N/S15001210, 215, 18, 0.00%, Corn, field, meal-Cooked; Fresh or N/S;Boiled/baked 8003750, 212, 24, 0.00%, Tomato-Cooked; Fresh or N/S; Boiled 8003760, 212, 25, 0.00%, Tomato, paste-Cooked; Fresh or N/S; Boiled20003650, 900, 20, 0.00%, Sunflower, oil-Refined; FF N/A; Cook Meth N/S25002920, 210, 21, 0.00%, Pork, meat byproducts-Cooked; Fresh or N/S; CookMeth N/S 1013140, 110, 19, 0.00%, Radish, roots-Uncooked; Fresh or N/S; Cook Meth N/S 5010830, 212, 19, 0.00%, Cauliflower-Cooked; Fresh or N/S; Boiled95000730, 210, 3, 0.00%, Cactus-Cooked; Fresh or N/S; Cook Meth N/S15001201, 230, 20, 0.00%, Corn, field, flour-babyfood-Cooked; Dried; CookMeth N/S 1033000, 211, 5, 0.00%, Potato, tuber, w/o peel-Cooked; Fresh or N/S; Baked 1010500, 250, 18, 0.00%, Beet, garden, roots-Cooked; Cured etc; Cook MethN/S 1033661, 240, 12, 0.00%, Sweet potato-babyfood-Cooked; Canned; Cook Meth N/S95002630, 211, 24, 0.00%, Peanut-Cooked; Fresh or N/S; Baked21000470, 240, 22, 0.00%, Beef, fat-Cooked; Canned; Cook Meth N/S25002950, 210, 19, 0.00%, Pork, liver-Cooked; Fresh or N/S; Cook Meth N/S 1032990, 212, 7, 0.00%, Potato, tuber, w/peel-Cooked; Fresh or N/S; Boiled10002000, 212, 20, 0.00%, Lemon, juice-Cooked; Fresh or N/S; Boiled 9023090, 211, 19, 0.00%, Pumpkin, seed-Cooked; Fresh or N/S; Baked10002420, 210, 19, 0.00%, Orange, peel-Cooked; Fresh or N/S; Cook Meth N/S20003640, 110, 15, 0.00%, Sunflower, seed-Uncooked; Fresh or N/S; Cook MethN/S 8003770, 211, 23, 0.00%, Tomato, puree-Cooked; Fresh or N/S; Baked 6032030, 232, 23, 0.00%, Lentil, seed-Cooked; Dried; Boiled25002931, 240, 8, 0.00%, Pork, fat-babyfood-Cooked; Canned; Cook Meth N/S 9023080, 215, 7, 0.00%, Pumpkin-Cooked; Fresh or N/S; Boiled/baked21000460, 210, 20, 0.00%, Beef, meat byproducts-Cooked; Fresh or N/S; CookMeth N/S15004010, 230, 25, 0.00%, Wheat, grain-Cooked; Dried; Cook Meth N/S15003240, 210, 1, 0.00%, Rice, brown-Cooked; Fresh or N/S; Cook Meth N/S95000190, 212, 12, 0.00%, Asparagus-Cooked; Fresh or N/S; Boiled20003640, 210, 20, 0.00%, Sunflower, seed-Cooked; Fresh or N/S; Cook Meth N/S 8003740, 210, 20, 0.00%, Tomatillo-Cooked; Fresh or N/S; Cook Meth N/S15001210, 210, 20, 0.00%, Corn, field, meal-Cooked; Fresh or N/S; Cook MethN/S

342

20003640, 230, 19, 0.00%, Sunflower, seed-Cooked; Dried; Cook Meth N/S 6003481, 230, 21, 0.00%, Soybean, flour-babyfood-Cooked; Dried; Cook MethN/S15001210, 232, 21, 0.00%, Corn, field, meal-Cooked; Dried; Boiled15001210, 212, 19, 0.00%, Corn, field, meal-Cooked; Fresh or N/S; Boiled21000440, 240, 18, 0.00%, Beef, meat-Cooked; Canned; Cook Meth N/S 5010830, 222, 19, 0.00%, Cauliflower-Cooked; Frozen; Boiled25002901, 240, 7, 0.00%, Pork, meat-babyfood-Cooked; Canned; Cook Meth N/S15001230, 230, 17, 0.00%, Corn, field, starch-Cooked; Dried; Cook Meth N/S 1032990, 211, 7, 0.00%, Potato, tuber, w/peel-Cooked; Fresh or N/S; Baked 8003740, 240, 18, 0.00%, Tomatillo-Cooked; Canned; Cook Meth N/S15001240, 211, 19, 0.00%, Corn, field, syrup-Cooked; Fresh or N/S; Baked12002870, 130, 2, 0.00%, Plum, prune, dried-Uncooked; Dried; Cook Meth N/S 8003750, 240, 7, 0.00%, Tomato-Cooked; Canned; Cook Meth N/S15001240, 210, 11, 0.00%, Corn, field, syrup-Cooked; Fresh or N/S; Cook MethN/S 1033660, 211, 6, 0.00%, Sweet potato-Cooked; Fresh or N/S; Baked 8002700, 221, 1, 0.00%, Pepper, bell-Cooked; Frozen; Baked10002420, 212, 15, 0.00%, Orange, peel-Cooked; Fresh or N/S; Boiled 8002340, 212, 5, 0.00%, Okra-Cooked; Fresh or N/S; Boiled 8001480, 214, 1, 0.00%, Eggplant-Cooked; Fresh or N/S; Fried/baked15001230, 210, 9, 0.00%, Corn, field, starch-Cooked; Fresh or N/S; Cook MethN/S11000070, 150, 1, 0.00%, Apple, fruit with peel-Uncooked; Cured etc; CookMeth N/S25002930, 221, 1, 0.00%, Pork, fat-Cooked; Frozen; Baked 6030420, 210, 15, 0.00%, Bean, pinto, seed-Cooked; Fresh or N/S; Cook MethN/S 6003481, 240, 12, 0.00%, Soybean, flour-babyfood-Cooked; Canned; Cook MethN/S27002220, 230, 7, 0.00%, Milk, fat-Cooked; Dried; Cook Meth N/S25002930, 242, 5, 0.00%, Pork, fat-Cooked; Canned; Boiled11002680, 120, 3, 0.00%, Pear, juice-Uncooked; Frozen; Cook Meth N/S 8001480, 212, 6, 0.00%, Eggplant-Cooked; Fresh or N/S; Boiled15004010, 232, 4, 0.00%, Wheat, grain-Cooked; Dried; Boiled 9023080, 211, 3, 0.00%, Pumpkin-Cooked; Fresh or N/S; Baked95003601, 240, 1, 0.00%, Strawberry, juice-babyfood-Cooked; Canned; CookMeth N/S10002411, 240, 2, 0.00%, Orange, juice-babyfood-Cooked; Canned; Cook MethN/S95002640, 240, 11, 0.00%, Peanut, butter-Cooked; Canned; Cook Meth N/S10001990, 210, 2, 0.00%, Lemon-Cooked; Fresh or N/S; Cook Meth N/S25002900, 240, 4, 0.00%, Pork, meat-Cooked; Canned; Cook Meth N/S95001790, 110, 4, 0.00%, Grape, wine and sherry-Uncooked; Fresh or N/S; CookMeth N/S14002820, 211, 4, 0.00%, Pistachio-Cooked; Fresh or N/S; Baked27002220, 213, 5, 0.00%, Milk, fat-Cooked; Fresh or N/S; Fried25002900, 242, 5, 0.00%, Pork, meat-Cooked; Canned; Boiled15001240, 212, 7, 0.00%, Corn, field, syrup-Cooked; Fresh or N/S; Boiled14000810, 211, 4, 0.00%, Cashew-Cooked; Fresh or N/S; Baked12002600, 210, 1, 0.00%, Peach-Cooked; Fresh or N/S; Cook Meth N/S15001200, 231, 6, 0.00%, Corn, field, flour-Cooked; Dried; Baked 8003770, 242, 2, 0.00%, Tomato, puree-Cooked; Canned; Boiled10001060, 211, 2, 0.00%, Citrus citron-Cooked; Fresh or N/S; Baked 1030820, 231, 2, 0.00%, Cassava-Cooked; Dried; Baked15001270, 242, 2, 0.00%, Corn, sweet-Cooked; Canned; Boiled15001230, 110, 4, 0.00%, Corn, field, starch-Uncooked; Fresh or N/S; CookMeth N/S15001200, 232, 1, 0.00%, Corn, field, flour-Cooked; Dried; Boiled27022240, 110, 6, 0.00%, Milk, water-Uncooked; Fresh or N/S; Cook Meth N/S 8003750, 210, 6, 0.00%, Tomato-Cooked; Fresh or N/S; Cook Meth N/S25002930, 251, 3, 0.00%, Pork, fat-Cooked; Cured etc; Baked15003240, 215, 2, 0.00%, Rice, brown-Cooked; Fresh or N/S; Boiled/baked95000230, 240, 2, 0.00%, Banana-Cooked; Canned; Cook Meth N/S 8002700, 242, 2, 0.00%, Pepper, bell-Cooked; Canned; Boiled

343

15003230, 232, 4, 0.00%, Rice, white-Cooked; Dried; Boiled 8003770, 232, 1, 0.00%, Tomato, puree-Cooked; Dried; Boiled15001210, 211, 3, 0.00%, Corn, field, meal-Cooked; Fresh or N/S; Baked 8002710, 213, 1, 0.00%, Pepper, bell, dried-Cooked; Fresh or N/S; Fried 1010780, 110, 2, 0.00%, Carrot-Uncooked; Fresh or N/S; Cook Meth N/S 4012480, 232, 1, 0.00%, Parsley, leaves-Cooked; Dried; Boiled15004010, 231, 4, 0.00%, Wheat, grain-Cooked; Dried; Baked 1010781, 240, 2, 0.00%, Carrot-babyfood-Cooked; Canned; Cook Meth N/S 8003750, 211, 2, 0.00%, Tomato-Cooked; Fresh or N/S; Baked15001200, 213, 3, 0.00%, Corn, field, flour-Cooked; Fresh or N/S; Fried 1032980, 242, 1, 0.00%, Potato, flour-Cooked; Canned; Boiled 8003771, 240, 2, 0.00%, Tomato, puree-babyfood-Cooked; Canned; Cook MethN/S 4012480, 211, 2, 0.00%, Parsley, leaves-Cooked; Fresh or N/S; Baked15004040, 230, 2, 0.00%, Wheat, bran-Cooked; Dried; Cook Meth N/S11000110, 211, 1, 0.00%, Apple, sauce-Cooked; Fresh or N/S; Baked 1033000, 242, 1, 0.00%, Potato, tuber, w/o peel-Cooked; Canned; Boiled 8003790, 110, 1, 0.00%, Tomato, juice-Uncooked; Fresh or N/S; Cook Meth N/S14002690, 211, 1, 0.00%, Pecan-Cooked; Fresh or N/S; Baked 4012040, 110, 2, 0.00%, Lettuce, head-Uncooked; Fresh or N/S; Cook Meth N/S25002920, 232, 2, 0.00%, Pork, meat byproducts-Cooked; Dried; Boiled23001690, 212, 1, 0.00%, Goat, meat-Cooked; Fresh or N/S; Boiled15001270, 222, 2, 0.00%, Corn, sweet-Cooked; Frozen; Boiled26003390, 211, 2, 0.00%, Sheep, meat-Cooked; Fresh or N/S; Baked15001260, 231, 2, 0.00%, Corn, pop-Cooked; Dried; Baked21000450, 230, 2, 0.00%, Beef, meat, dried-Cooked; Dried; Cook Meth N/S25002900, 253, 1, 0.00%, Pork, meat-Cooked; Cured etc; Fried21000470, 232, 2, 0.00%, Beef, fat-Cooked; Dried; Boiled12002860, 211, 2, 0.00%, Plum, prune, fresh-Cooked; Fresh or N/S; Baked15003250, 110, 1, 0.00%, Rice, flour-Uncooked; Fresh or N/S; Cook Meth N/S 1033000, 221, 1, 0.00%, Potato, tuber, w/o peel-Cooked; Frozen; Baked 9010750, 240, 1, 0.00%, Cantaloupe-Cooked; Canned; Cook Meth N/S 8003790, 211, 2, 0.00%, Tomato, juice-Cooked; Fresh or N/S; Baked27002220, 240, 1, 0.00%, Milk, fat-Cooked; Canned; Cook Meth N/S11002680, 110, 1, 0.00%, Pear, juice-Uncooked; Fresh or N/S; Cook Meth N/S95002630, 210, 1, 0.00%, Peanut-Cooked; Fresh or N/S; Cook Meth N/S 9023560, 212, 1, 0.00%, Squash, summer-Cooked; Fresh or N/S; Boiled95001300, 240, 1, 0.00%, Cranberry-Cooked; Canned; Cook Meth N/S95002810, 211, 1, 0.00%, Pineapple, juice-Cooked; Fresh or N/S; Baked95002790, 211, 1, 0.00%, Pineapple-Cooked; Fresh or N/S; Baked10001800, 110, 1, 0.00%, Grapefruit-Uncooked; Fresh or N/S; Cook Meth N/S14000810, 210, 1, 0.00%, Cashew-Cooked; Fresh or N/S; Cook Meth N/S14003910, 210, 1, 0.00%, Walnut-Cooked; Fresh or N/S; Cook Meth N/S 6003470, 240, 1, 0.00%, Soybean, seed-Cooked; Canned; Cook Meth N/S95000230, 120, 1, 0.00%, Banana-Uncooked; Frozen; Cook Meth N/S 9023571, 240, 1, 0.00%, Squash, winter-babyfood-Cooked; Canned; Cook MethN/S11000070, 211, 1, 0.00%, Apple, fruit with peel-Cooked; Fresh or N/S; Baked26003410, 211, 1, 0.00%, Sheep, fat-Cooked; Fresh or N/S; Baked 1033000, 210, 1, 0.00%, Potato, tuber, w/o peel-Cooked; Fresh or N/S; CookMeth N/S 6003481, 130, 1, 0.00%, Soybean, flour-babyfood-Uncooked; Dried; Cook MethN/S12002600, 120, 1, 0.00%, Peach-Uncooked; Frozen; Cook Meth N/S 6003470, 212, 1, 0.00%, Soybean, seed-Cooked; Fresh or N/S; Boiled10002420, 240, 1, 0.00%, Orange, peel-Cooked; Canned; Cook Meth N/S95002790, 210, 1, 0.00%, Pineapple-Cooked; Fresh or N/S; Cook Meth N/S 6030400, 210, 1, 0.00%, Bean, navy, seed-Cooked; Fresh or N/S; Cook MethN/S 6030350, 210, 1, 0.00%, Bean, great northern, seed-Cooked; Fresh or N/S;Cook Meth N/S 1030820, 240, 1, 0.00%, Cassava-Cooked; Canned; Cook Meth N/S15004021, 240, 1, 0.00%, Wheat, flour-babyfood-Cooked; Canned; Cook Meth N/S

344

HispanicsLow percentile for CEC records: 95 Exposure (mg/day) = 0.000510High percentile for CEC records: 100 Exposure (mg/day) = 0.157992Number of actual records in this interval: 6978

Critical foods/foodforms for this population (as derived from these records): N=number of appearances in all records (including duplicates) %=percent of total exposure for all records (including duplicates)

Food, FF, N , Percent, Food Name --------, ---, -----, -------, -------------12002620, 110, 133, 9.38%, Peach, juice-Uncooked; Fresh or N/S; Cook Meth N/S 8002720, 110, 1003, 8.53%, Pepper, nonbell-Uncooked; Fresh or N/S; Cook MethN/S12002620, 240, 171, 7.54%, Peach, juice-Cooked; Canned; Cook Meth N/S95002810, 110, 913, 6.66%, Pineapple, juice-Uncooked; Fresh or N/S; Cook MethN/S10002000, 110, 972, 4.91%, Lemon, juice-Uncooked; Fresh or N/S; Cook Meth N/S12000910, 110, 57, 4.78%, Cherry, juice-Uncooked; Fresh or N/S; Cook Meth N/S11000070, 110, 330, 4.14%, Apple, fruit with peel-Uncooked; Fresh or N/S; CookMeth N/S12002880, 110, 76, 4.00%, Plum, prune, juice-Uncooked; Fresh or N/S; CookMeth N/S 8002720, 210, 715, 3.92%, Pepper, nonbell-Cooked; Fresh or N/S; Cook Meth N/S 8002720, 212, 845, 3.68%, Pepper, nonbell-Cooked; Fresh or N/S; Boiled12000910, 210, 448, 2.13%, Cherry, juice-Cooked; Fresh or N/S; Cook Meth N/S95001750, 110, 90, 1.86%, Grape-Uncooked; Fresh or N/S; Cook Meth N/S 8002720, 213, 291, 1.73%, Pepper, nonbell-Cooked; Fresh or N/S; Fried 8002720, 240, 401, 1.66%, Pepper, nonbell-Cooked; Canned; Cook Meth N/S12002621, 240, 76, 1.34%, Peach, juice-babyfood-Cooked; Canned; Cook Meth N/S10001810, 110, 216, 1.21%, Grapefruit, juice-Uncooked; Fresh or N/S; Cook MethN/S95002810, 240, 616, 1.19%, Pineapple, juice-Cooked; Canned; Cook Meth N/S 9020880, 210, 95, 1.17%, Chayote, fruit-Cooked; Fresh or N/S; Cook Meth N/S10003690, 110, 175, 1.15%, Tangerine-Uncooked; Fresh or N/S; Cook Meth N/S11000100, 110, 661, 1.01%, Apple, juice-Uncooked; Fresh or N/S; Cook Meth N/S 4020860, 110, 38, 0.94%, Celery, juice-Uncooked; Fresh or N/S; Cook Meth N/S 8002340, 210, 38, 0.73%, Okra-Cooked; Fresh or N/S; Cook Meth N/S10003700, 240, 820, 0.72%, Tangerine, juice-Cooked; Canned; Cook Meth N/S10001810, 120, 169, 0.69%, Grapefruit, juice-Uncooked; Frozen; Cook Meth N/S 8002340, 220, 57, 0.68%, Okra-Cooked; Frozen; Cook Meth N/S10002000, 240, 790, 0.64%, Lemon, juice-Cooked; Canned; Cook Meth N/S12000910, 240, 318, 0.64%, Cherry, juice-Cooked; Canned; Cook Meth N/S95002350, 240, 16, 0.60%, Olive-Cooked; Canned; Cook Meth N/S13010580, 240, 544, 0.58%, Boysenberry-Cooked; Canned; Cook Meth N/S10002000, 130, 98, 0.55%, Lemon, juice-Uncooked; Dried; Cook Meth N/S12002600, 110, 65, 0.52%, Peach-Uncooked; Fresh or N/S; Cook Meth N/S 5020700, 210, 95, 0.52%, Cabbage, Chinese, bok choy-Cooked; Fresh or N/S;Cook Meth N/S10002070, 110, 58, 0.51%, Lime, juice-Uncooked; Fresh or N/S; Cook Meth N/S10002000, 210, 448, 0.48%, Lemon, juice-Cooked; Fresh or N/S; Cook Meth N/S27002220, 110, 2355, 0.47%, Milk, fat-Uncooked; Fresh or N/S; Cook Meth N/S13013200, 110, 29, 0.47%, Raspberry-Uncooked; Fresh or N/S; Cook Meth N/S10002070, 240, 704, 0.47%, Lime, juice-Cooked; Canned; Cook Meth N/S25002930, 210, 909, 0.42%, Pork, fat-Cooked; Fresh or N/S; Cook Meth N/S12002601, 240, 42, 0.42%, Peach-babyfood-Cooked; Canned; Cook Meth N/S12002600, 240, 68, 0.41%, Peach-Cooked; Canned; Cook Meth N/S13013200, 240, 45, 0.40%, Raspberry-Cooked; Canned; Cook Meth N/S11002660, 110, 35, 0.39%, Pear-Uncooked; Fresh or N/S; Cook Meth N/S12002610, 130, 39, 0.34%, Peach, dried-Uncooked; Dried; Cook Meth N/S15003251, 230, 227, 0.33%, Rice, flour-babyfood-Cooked; Dried; Cook Meth N/S25002930, 213, 520, 0.31%, Pork, fat-Cooked; Fresh or N/S; Fried10001990, 110, 151, 0.30%, Lemon-Uncooked; Fresh or N/S; Cook Meth N/S11000090, 211, 90, 0.30%, Apple, dried-Cooked; Fresh or N/S; Baked

345

10001810, 240, 518, 0.29%, Grapefruit, juice-Cooked; Canned; Cook Meth N/S95001760, 110, 155, 0.29%, Grape, juice-Uncooked; Fresh or N/S; Cook Meth N/S15003250, 230, 279, 0.28%, Rice, flour-Cooked; Dried; Cook Meth N/S10002410, 110, 788, 0.26%, Orange, juice-Uncooked; Fresh or N/S; Cook Meth N/S12000911, 240, 57, 0.25%, Cherry, juice-babyfood-Cooked; Canned; Cook MethN/S95003590, 110, 22, 0.24%, Strawberry-Uncooked; Fresh or N/S; Cook Meth N/S25002930, 250, 455, 0.24%, Pork, fat-Cooked; Cured etc; Cook Meth N/S11000101, 240, 104, 0.23%, Apple, juice-babyfood-Cooked; Canned; Cook Meth N/S95002810, 120, 157, 0.23%, Pineapple, juice-Uncooked; Frozen; Cook Meth N/S15001240, 240, 1540, 0.23%, Corn, field, syrup-Cooked; Canned; Cook Meth N/S 8002720, 220, 38, 0.23%, Pepper, nonbell-Cooked; Frozen; Cook Meth N/S95001760, 240, 231, 0.21%, Grape, juice-Cooked; Canned; Cook Meth N/S95002811, 240, 91, 0.20%, Pineapple, juice-babyfood-Cooked; Canned; Cook MethN/S13020570, 211, 28, 0.19%, Blueberry-Cooked; Fresh or N/S; Baked 8002700, 210, 47, 0.19%, Pepper, bell-Cooked; Fresh or N/S; Cook Meth N/S13020570, 110, 37, 0.18%, Blueberry-Uncooked; Fresh or N/S; Cook Meth N/S11000111, 240, 79, 0.17%, Apple, sauce-babyfood-Cooked; Canned; Cook Meth N/S10002400, 110, 50, 0.16%, Orange-Uncooked; Fresh or N/S; Cook Meth N/S10002070, 120, 200, 0.16%, Lime, juice-Uncooked; Frozen; Cook Meth N/S15004020, 211, 1184, 0.16%, Wheat, flour-Cooked; Fresh or N/S; Baked13010561, 240, 11, 0.15%, Blackberry, juice-babyfood-Cooked; Canned; CookMeth N/S25002930, 230, 367, 0.15%, Pork, fat-Cooked; Dried; Cook Meth N/S25002930, 211, 389, 0.15%, Pork, fat-Cooked; Fresh or N/S; Baked13010580, 120, 121, 0.15%, Boysenberry-Uncooked; Frozen; Cook Meth N/S 8002720, 150, 42, 0.14%, Pepper, nonbell-Uncooked; Cured etc; Cook Meth N/S11002661, 240, 8, 0.14%, Pear-babyfood-Cooked; Canned; Cook Meth N/S10002060, 110, 38, 0.13%, Lime-Uncooked; Fresh or N/S; Cook Meth N/S15001200, 214, 730, 0.12%, Corn, field, flour-Cooked; Fresh or N/S;Fried/baked95002350, 211, 15, 0.12%, Olive-Cooked; Fresh or N/S; Baked11002660, 240, 18, 0.11%, Pear-Cooked; Canned; Cook Meth N/S25002930, 253, 202, 0.11%, Pork, fat-Cooked; Cured etc; Fried11000110, 212, 39, 0.10%, Apple, sauce-Cooked; Fresh or N/S; Boiled12000900, 110, 20, 0.10%, Cherry-Uncooked; Fresh or N/S; Cook Meth N/S13020571, 240, 2, 0.10%, Blueberry-babyfood-Cooked; Canned; Cook Meth N/S 8002700, 110, 41, 0.10%, Pepper, bell-Uncooked; Fresh or N/S; Cook Meth N/S13010550, 240, 41, 0.10%, Blackberry-Cooked; Canned; Cook Meth N/S12000140, 240, 29, 0.10%, Apricot, juice-Cooked; Canned; Cook Meth N/S13020570, 214, 4, 0.10%, Blueberry-Cooked; Fresh or N/S; Fried/baked 8002730, 210, 118, 0.09%, Pepper, nonbell, dried-Cooked; Fresh or N/S; CookMeth N/S11000090, 130, 39, 0.09%, Apple, dried-Uncooked; Dried; Cook Meth N/S13013211, 240, 8, 0.09%, Raspberry, juice-babyfood-Cooked; Canned; Cook MethN/S 8002340, 150, 19, 0.09%, Okra-Uncooked; Cured etc; Cook Meth N/S11002670, 130, 39, 0.09%, Pear, dried-Uncooked; Dried; Cook Meth N/S11000100, 240, 207, 0.08%, Apple, juice-Cooked; Canned; Cook Meth N/S25002930, 240, 61, 0.08%, Pork, fat-Cooked; Canned; Cook Meth N/S15001200, 230, 390, 0.08%, Corn, field, flour-Cooked; Dried; Cook Meth N/S15001240, 110, 655, 0.08%, Corn, field, syrup-Uncooked; Fresh or N/S; CookMeth N/S12002881, 240, 19, 0.08%, Plum, prune, juice-babyfood-Cooked; Canned; CookMeth N/S 8003770, 210, 305, 0.08%, Tomato, puree-Cooked; Fresh or N/S; Cook Meth N/S 8002720, 211, 57, 0.08%, Pepper, nonbell-Cooked; Fresh or N/S; Baked10003700, 120, 121, 0.07%, Tangerine, juice-Uncooked; Frozen; Cook Meth N/S 8002700, 215, 48, 0.07%, Pepper, bell-Cooked; Fresh or N/S; Boiled/baked95003600, 240, 15, 0.07%, Strawberry, juice-Cooked; Canned; Cook Meth N/S25002900, 250, 347, 0.07%, Pork, meat-Cooked; Cured etc; Cook Meth N/S21000470, 210, 482, 0.07%, Beef, fat-Cooked; Fresh or N/S; Cook Meth N/S21000440, 210, 460, 0.07%, Beef, meat-Cooked; Fresh or N/S; Cook Meth N/S 8002720, 215, 228, 0.07%, Pepper, nonbell-Cooked; Fresh or N/S; Boiled/baked

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12002300, 110, 17, 0.07%, Nectarine-Uncooked; Fresh or N/S; Cook Meth N/S25002930, 212, 211, 0.07%, Pork, fat-Cooked; Fresh or N/S; Boiled10002000, 120, 120, 0.06%, Lemon, juice-Uncooked; Frozen; Cook Meth N/S 8002730, 240, 187, 0.06%, Pepper, nonbell, dried-Cooked; Canned; Cook MethN/S10002410, 120, 181, 0.06%, Orange, juice-Uncooked; Frozen; Cook Meth N/S25002930, 232, 138, 0.06%, Pork, fat-Cooked; Dried; Boiled11000081, 240, 7, 0.06%, Apple, peeled fruit-babyfood-Cooked; Canned; CookMeth N/S95002360, 900, 154, 0.06%, Olive, oil-Refined; FF N/A; Cook Meth N/S25002900, 211, 146, 0.05%, Pork, meat-Cooked; Fresh or N/S; Baked 8003790, 212, 88, 0.05%, Tomato, juice-Cooked; Fresh or N/S; Boiled 8003770, 240, 259, 0.05%, Tomato, puree-Cooked; Canned; Cook Meth N/S95000230, 110, 458, 0.05%, Banana-Uncooked; Fresh or N/S; Cook Meth N/S12000910, 120, 118, 0.05%, Cherry, juice-Uncooked; Frozen; Cook Meth N/S11000090, 230, 65, 0.05%, Apple, dried-Cooked; Dried; Cook Meth N/S25002900, 213, 221, 0.05%, Pork, meat-Cooked; Fresh or N/S; Fried10002001, 240, 49, 0.05%, Lemon, juice-babyfood-Cooked; Canned; Cook Meth N/S 8002730, 212, 85, 0.04%, Pepper, nonbell, dried-Cooked; Fresh or N/S; Boiled95002350, 212, 1, 0.04%, Olive-Cooked; Fresh or N/S; Boiled21000440, 213, 348, 0.04%, Beef, meat-Cooked; Fresh or N/S; Fried15001240, 130, 235, 0.04%, Corn, field, syrup-Uncooked; Dried; Cook Meth N/S12000900, 211, 7, 0.04%, Cherry-Cooked; Fresh or N/S; Baked15003251, 240, 86, 0.04%, Rice, flour-babyfood-Cooked; Canned; Cook Meth N/S95001750, 210, 31, 0.04%, Grape-Cooked; Fresh or N/S; Cook Meth N/S15001210, 233, 195, 0.04%, Corn, field, meal-Cooked; Dried; Fried 8002700, 213, 12, 0.04%, Pepper, bell-Cooked; Fresh or N/S; Fried95001761, 240, 58, 0.04%, Grape, juice-babyfood-Cooked; Canned; Cook Meth N/S95002800, 130, 39, 0.04%, Pineapple, dried-Uncooked; Dried; Cook Meth N/S 6010430, 242, 6, 0.04%, Bean, snap, succulent-Cooked; Canned; Boiled25002900, 210, 248, 0.04%, Pork, meat-Cooked; Fresh or N/S; Cook Meth N/S 4013551, 240, 4, 0.04%, Spinach-babyfood-Cooked; Canned; Cook Meth N/S 8003770, 212, 190, 0.04%, Tomato, puree-Cooked; Fresh or N/S; Boiled12000900, 240, 16, 0.04%, Cherry-Cooked; Canned; Cook Meth N/S 9010750, 110, 10, 0.04%, Cantaloupe-Uncooked; Fresh or N/S; Cook Meth N/S 1034070, 110, 40, 0.03%, Yam bean-Uncooked; Fresh or N/S; Cook Meth N/S12000121, 240, 6, 0.03%, Apricot-babyfood-Cooked; Canned; Cook Meth N/S15004020, 210, 208, 0.03%, Wheat, flour-Cooked; Fresh or N/S; Cook Meth N/S12000141, 240, 7, 0.03%, Apricot, juice-babyfood-Cooked; Canned; Cook MethN/S13013210, 110, 2, 0.03%, Raspberry, juice-Uncooked; Fresh or N/S; Cook MethN/S11002681, 240, 9, 0.03%, Pear, juice-babyfood-Cooked; Canned; Cook Meth N/S15004020, 232, 193, 0.03%, Wheat, flour-Cooked; Dried; Boiled95003600, 110, 2, 0.03%, Strawberry, juice-Uncooked; Fresh or N/S; Cook MethN/S21000470, 213, 259, 0.03%, Beef, fat-Cooked; Fresh or N/S; Fried21000470, 212, 160, 0.03%, Beef, fat-Cooked; Fresh or N/S; Boiled20003651, 900, 117, 0.03%, Sunflower, oil-babyfood-Refined; FF N/A; Cook MethN/S11002660, 210, 18, 0.03%, Pear-Cooked; Fresh or N/S; Cook Meth N/S 8002730, 211, 42, 0.03%, Pepper, nonbell, dried-Cooked; Fresh or N/S; Baked 9014000, 110, 19, 0.02%, Watermelon, juice-Uncooked; Fresh or N/S; Cook MethN/S10002410, 240, 154, 0.02%, Orange, juice-Cooked; Canned; Cook Meth N/S27002220, 232, 114, 0.02%, Milk, fat-Cooked; Dried; Boiled27002220, 120, 140, 0.02%, Milk, fat-Uncooked; Frozen; Cook Meth N/S21000440, 212, 180, 0.02%, Beef, meat-Cooked; Fresh or N/S; Boiled95001760, 120, 41, 0.02%, Grape, juice-Uncooked; Frozen; Cook Meth N/S95003600, 210, 17, 0.02%, Strawberry, juice-Cooked; Fresh or N/S; Cook MethN/S11002680, 240, 6, 0.02%, Pear, juice-Cooked; Canned; Cook Meth N/S 9021350, 110, 52, 0.02%, Cucumber-Uncooked; Fresh or N/S; Cook Meth N/S11000091, 230, 8, 0.02%, Apple, dried-babyfood-Cooked; Dried; Cook Meth N/S 4012480, 210, 68, 0.02%, Parsley, leaves-Cooked; Fresh or N/S; Cook Meth N/S

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10002000, 211, 74, 0.02%, Lemon, juice-Cooked; Fresh or N/S; Baked95001750, 240, 9, 0.02%, Grape-Cooked; Canned; Cook Meth N/S 1010790, 110, 20, 0.02%, Carrot, juice-Uncooked; Fresh or N/S; Cook Meth N/S12000120, 110, 21, 0.02%, Apricot-Uncooked; Fresh or N/S; Cook Meth N/S95002630, 211, 39, 0.02%, Peanut-Cooked; Fresh or N/S; Baked21000440, 211, 99, 0.02%, Beef, meat-Cooked; Fresh or N/S; Baked 4012480, 110, 38, 0.02%, Parsley, leaves-Uncooked; Fresh or N/S; Cook MethN/S15001210, 230, 176, 0.02%, Corn, field, meal-Cooked; Dried; Cook Meth N/S 8002730, 213, 118, 0.02%, Pepper, nonbell, dried-Cooked; Fresh or N/S; Fried 6030420, 232, 149, 0.02%, Bean, pinto, seed-Cooked; Dried; Boiled 8002720, 230, 19, 0.02%, Pepper, nonbell-Cooked; Dried; Cook Meth N/S12000130, 211, 2, 0.02%, Apricot, dried-Cooked; Fresh or N/S; Baked95003590, 240, 6, 0.02%, Strawberry-Cooked; Canned; Cook Meth N/S 1033000, 212, 40, 0.01%, Potato, tuber, w/o peel-Cooked; Fresh or N/S;Boiled15001200, 210, 84, 0.01%, Corn, field, flour-Cooked; Fresh or N/S; Cook MethN/S15001241, 240, 29, 0.01%, Corn, field, syrup-babyfood-Cooked; Canned; CookMeth N/S27002220, 215, 79, 0.01%, Milk, fat-Cooked; Fresh or N/S; Boiled/baked 8002700, 212, 14, 0.01%, Pepper, bell-Cooked; Fresh or N/S; Boiled12000120, 240, 24, 0.01%, Apricot-Cooked; Canned; Cook Meth N/S 8003760, 210, 100, 0.01%, Tomato, paste-Cooked; Fresh or N/S; Cook Meth N/S13013210, 240, 19, 0.01%, Raspberry, juice-Cooked; Canned; Cook Meth N/S27002220, 211, 80, 0.01%, Milk, fat-Cooked; Fresh or N/S; Baked 6010430, 212, 4, 0.01%, Bean, snap, succulent-Cooked; Fresh or N/S; Boiled15004020, 215, 79, 0.01%, Wheat, flour-Cooked; Fresh or N/S; Boiled/baked95000730, 210, 22, 0.01%, Cactus-Cooked; Fresh or N/S; Cook Meth N/S10002070, 250, 3, 0.01%, Lime, juice-Cooked; Cured etc; Cook Meth N/S15004020, 231, 129, 0.01%, Wheat, flour-Cooked; Dried; Baked15001260, 230, 102, 0.01%, Corn, pop-Cooked; Dried; Cook Meth N/S13020570, 213, 3, 0.01%, Blueberry-Cooked; Fresh or N/S; Fried21000470, 211, 47, 0.01%, Beef, fat-Cooked; Fresh or N/S; Baked13020570, 240, 24, 0.01%, Blueberry-Cooked; Canned; Cook Meth N/S15001200, 211, 57, 0.01%, Corn, field, flour-Cooked; Fresh or N/S; Baked15004020, 212, 66, 0.01%, Wheat, flour-Cooked; Fresh or N/S; Boiled 8002700, 211, 13, 0.01%, Pepper, bell-Cooked; Fresh or N/S; Baked 6010430, 222, 1, 0.01%, Bean, snap, succulent-Cooked; Frozen; Boiled 5022290, 212, 2, 0.01%, Mustard greens-Cooked; Fresh or N/S; Boiled 1030820, 210, 38, 0.01%, Cassava-Cooked; Fresh or N/S; Cook Meth N/S25002930, 251, 24, 0.01%, Pork, fat-Cooked; Cured etc; Baked 4012480, 212, 62, 0.01%, Parsley, leaves-Cooked; Fresh or N/S; Boiled13013200, 120, 2, 0.01%, Raspberry-Uncooked; Frozen; Cook Meth N/S 8002700, 250, 3, 0.01%, Pepper, bell-Cooked; Cured etc; Cook Meth N/S11000110, 210, 5, 0.01%, Apple, sauce-Cooked; Fresh or N/S; Cook Meth N/S27002220, 230, 43, 0.01%, Milk, fat-Cooked; Dried; Cook Meth N/S25002900, 240, 39, 0.01%, Pork, meat-Cooked; Canned; Cook Meth N/S15001240, 120, 63, 0.01%, Corn, field, syrup-Uncooked; Frozen; Cook Meth N/S95002790, 240, 31, 0.01%, Pineapple-Cooked; Canned; Cook Meth N/S 9023080, 211, 20, 0.01%, Pumpkin-Cooked; Fresh or N/S; Baked 1030821, 240, 63, 0.01%, Cassava-babyfood-Cooked; Canned; Cook Meth N/S95002640, 210, 75, 0.01%, Peanut, butter-Cooked; Fresh or N/S; Cook Meth N/S 1010790, 240, 21, 0.01%, Carrot, juice-Cooked; Canned; Cook Meth N/S 6030420, 230, 53, 0.01%, Bean, pinto, seed-Cooked; Dried; Cook Meth N/S23001690, 211, 19, 0.01%, Goat, meat-Cooked; Fresh or N/S; Baked12000130, 130, 2, 0.01%, Apricot, dried-Uncooked; Dried; Cook Meth N/S11000070, 211, 1, 0.01%, Apple, fruit with peel-Cooked; Fresh or N/S; Baked 9021350, 240, 14, 0.01%, Cucumber-Cooked; Canned; Cook Meth N/S 8003750, 110, 25, 0.01%, Tomato-Uncooked; Fresh or N/S; Cook Meth N/S95002350, 210, 2, 0.01%, Olive-Cooked; Fresh or N/S; Cook Meth N/S10002071, 240, 38, 0.01%, Lime, juice-babyfood-Cooked; Canned; Cook Meth N/S12000901, 240, 1, 0.01%, Cherry-babyfood-Cooked; Canned; Cook Meth N/S13013210, 120, 10, 0.01%, Raspberry, juice-Uncooked; Frozen; Cook Meth N/S

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15001241, 130, 22, 0.01%, Corn, field, syrup-babyfood-Uncooked; Dried; CookMeth N/S 8003740, 110, 19, 0.01%, Tomatillo-Uncooked; Fresh or N/S; Cook Meth N/S 1031390, 212, 20, 0.01%, Dasheen, corm-Cooked; Fresh or N/S; Boiled 9011870, 110, 1, 0.01%, Honeydew melon-Uncooked; Fresh or N/S; Cook MethN/S25002900, 251, 21, 0.01%, Pork, meat-Cooked; Cured etc; Baked 8002720, 232, 25, 0.01%, Pepper, nonbell-Cooked; Dried; Boiled15001231, 240, 48, 0.01%, Corn, field, starch-babyfood-Cooked; Canned; CookMeth N/S15001210, 232, 18, 0.01%, Corn, field, meal-Cooked; Dried; Boiled13013201, 240, 2, 0.00%, Raspberry-babyfood-Cooked; Canned; Cook Meth N/S15004020, 240, 55, 0.00%, Wheat, flour-Cooked; Canned; Cook Meth N/S 8002730, 232, 43, 0.00%, Pepper, nonbell, dried-Cooked; Dried; Boiled11000080, 240, 1, 0.00%, Apple, peeled fruit-Cooked; Canned; Cook Meth N/S 8002700, 240, 1, 0.00%, Pepper, bell-Cooked; Canned; Cook Meth N/S12002600, 211, 1, 0.00%, Peach-Cooked; Fresh or N/S; Baked21000440, 240, 38, 0.00%, Beef, meat-Cooked; Canned; Cook Meth N/S21000470, 240, 37, 0.00%, Beef, fat-Cooked; Canned; Cook Meth N/S27022240, 110, 46, 0.00%, Milk, water-Uncooked; Fresh or N/S; Cook Meth N/S13013200, 211, 3, 0.00%, Raspberry-Cooked; Fresh or N/S; Baked15003250, 120, 19, 0.00%, Rice, flour-Uncooked; Frozen; Cook Meth N/S27002220, 212, 25, 0.00%, Milk, fat-Cooked; Fresh or N/S; Boiled27002220, 210, 33, 0.00%, Milk, fat-Cooked; Fresh or N/S; Cook Meth N/S25002931, 240, 21, 0.00%, Pork, fat-babyfood-Cooked; Canned; Cook Meth N/S 6032560, 232, 18, 0.00%, Pea, dry-Cooked; Dried; Boiled13020570, 120, 2, 0.00%, Blueberry-Uncooked; Frozen; Cook Meth N/S15003250, 210, 28, 0.00%, Rice, flour-Cooked; Fresh or N/S; Cook Meth N/S15004020, 230, 33, 0.00%, Wheat, flour-Cooked; Dried; Cook Meth N/S 8003750, 215, 20, 0.00%, Tomato-Cooked; Fresh or N/S; Boiled/baked 9013990, 110, 16, 0.00%, Watermelon-Uncooked; Fresh or N/S; Cook Meth N/S14002690, 211, 36, 0.00%, Pecan-Cooked; Fresh or N/S; Baked25002920, 210, 19, 0.00%, Pork, meat byproducts-Cooked; Fresh or N/S; CookMeth N/S 8003750, 212, 24, 0.00%, Tomato-Cooked; Fresh or N/S; Boiled21000441, 240, 22, 0.00%, Beef, meat-babyfood-Cooked; Canned; Cook Meth N/S15001240, 211, 35, 0.00%, Corn, field, syrup-Cooked; Fresh or N/S; Baked15004020, 214, 25, 0.00%, Wheat, flour-Cooked; Fresh or N/S; Fried/baked13020570, 230, 1, 0.00%, Blueberry-Cooked; Dried; Cook Meth N/S15001200, 213, 24, 0.00%, Corn, field, flour-Cooked; Fresh or N/S; Fried25002900, 212, 23, 0.00%, Pork, meat-Cooked; Fresh or N/S; Boiled25002901, 240, 20, 0.00%, Pork, meat-babyfood-Cooked; Canned; Cook Meth N/S13020570, 210, 3, 0.00%, Blueberry-Cooked; Fresh or N/S; Cook Meth N/S12002850, 110, 5, 0.00%, Plum-Uncooked; Fresh or N/S; Cook Meth N/S 8003790, 240, 19, 0.00%, Tomato, juice-Cooked; Canned; Cook Meth N/S12002861, 240, 1, 0.00%, Plum, prune, fresh-babyfood-Cooked; Canned; CookMeth N/S15004020, 213, 21, 0.00%, Wheat, flour-Cooked; Fresh or N/S; Fried95001760, 210, 11, 0.00%, Grape, juice-Cooked; Fresh or N/S; Cook Meth N/S21000460, 210, 20, 0.00%, Beef, meat byproducts-Cooked; Fresh or N/S; CookMeth N/S 8003770, 211, 20, 0.00%, Tomato, puree-Cooked; Fresh or N/S; Baked 5010830, 212, 19, 0.00%, Cauliflower-Cooked; Fresh or N/S; Boiled15001241, 230, 7, 0.00%, Corn, field, syrup-babyfood-Cooked; Dried; CookMeth N/S 4011500, 110, 5, 0.00%, Endive-Uncooked; Fresh or N/S; Cook Meth N/S95000190, 212, 11, 0.00%, Asparagus-Cooked; Fresh or N/S; Boiled15001231, 130, 19, 0.00%, Corn, field, starch-babyfood-Uncooked; Dried; CookMeth N/S 6032030, 232, 19, 0.00%, Lentil, seed-Cooked; Dried; Boiled20003640, 230, 19, 0.00%, Sunflower, seed-Cooked; Dried; Cook Meth N/S12000900, 120, 1, 0.00%, Cherry-Uncooked; Frozen; Cook Meth N/S15001230, 230, 18, 0.00%, Corn, field, starch-Cooked; Dried; Cook Meth N/S 9010750, 240, 2, 0.00%, Cantaloupe-Cooked; Canned; Cook Meth N/S19011440, 240, 20, 0.00%, Dillweed-Cooked; Canned; Cook Meth N/S

349

15004021, 211, 19, 0.00%, Wheat, flour-babyfood-Cooked; Fresh or N/S; Baked 1033000, 211, 4, 0.00%, Potato, tuber, w/o peel-Cooked; Fresh or N/S; Baked10002411, 240, 9, 0.00%, Orange, juice-babyfood-Cooked; Canned; Cook MethN/S95001320, 240, 3, 0.00%, Cranberry, juice-Cooked; Canned; Cook Meth N/S 1033661, 240, 7, 0.00%, Sweet potato-babyfood-Cooked; Canned; Cook Meth N/S95003601, 240, 2, 0.00%, Strawberry, juice-babyfood-Cooked; Canned; CookMeth N/S 6003481, 240, 13, 0.00%, Soybean, flour-babyfood-Cooked; Canned; Cook MethN/S15001201, 230, 9, 0.00%, Corn, field, flour-babyfood-Cooked; Dried; CookMeth N/S95001320, 110, 2, 0.00%, Cranberry, juice-Uncooked; Fresh or N/S; Cook MethN/S13010550, 120, 4, 0.00%, Blackberry-Uncooked; Frozen; Cook Meth N/S 6003490, 210, 3, 0.00%, Soybean, soy milk-Cooked; Fresh or N/S; Cook MethN/S 1032990, 212, 5, 0.00%, Potato, tuber, w/peel-Cooked; Fresh or N/S; Boiled 8002340, 212, 3, 0.00%, Okra-Cooked; Fresh or N/S; Boiled95002790, 110, 4, 0.00%, Pineapple-Uncooked; Fresh or N/S; Cook Meth N/S11000100, 210, 7, 0.00%, Apple, juice-Cooked; Fresh or N/S; Cook Meth N/S26003391, 240, 5, 0.00%, Sheep, meat-babyfood-Cooked; Canned; Cook Meth N/S14003910, 211, 2, 0.00%, Walnut-Cooked; Fresh or N/S; Baked 1032990, 211, 2, 0.00%, Potato, tuber, w/peel-Cooked; Fresh or N/S; Baked12002600, 210, 1, 0.00%, Peach-Cooked; Fresh or N/S; Cook Meth N/S10001800, 110, 4, 0.00%, Grapefruit-Uncooked; Fresh or N/S; Cook Meth N/S23001690, 212, 3, 0.00%, Goat, meat-Cooked; Fresh or N/S; Boiled 2001010, 110, 4, 0.00%, Chicory, tops-Uncooked; Fresh or N/S; Cook Meth N/S15001240, 210, 4, 0.00%, Corn, field, syrup-Cooked; Fresh or N/S; Cook MethN/S 8003750, 210, 8, 0.00%, Tomato-Cooked; Fresh or N/S; Cook Meth N/S15004010, 211, 8, 0.00%, Wheat, grain-Cooked; Fresh or N/S; Baked14002820, 211, 2, 0.00%, Pistachio-Cooked; Fresh or N/S; Baked 9023560, 212, 3, 0.00%, Squash, summer-Cooked; Fresh or N/S; Boiled95000230, 240, 2, 0.00%, Banana-Cooked; Canned; Cook Meth N/S 8003740, 210, 3, 0.00%, Tomatillo-Cooked; Fresh or N/S; Cook Meth N/S10002000, 232, 1, 0.00%, Lemon, juice-Cooked; Dried; Boiled15001210, 210, 2, 0.00%, Corn, field, meal-Cooked; Fresh or N/S; Cook MethN/S 8003750, 240, 3, 0.00%, Tomato-Cooked; Canned; Cook Meth N/S 8003770, 232, 1, 0.00%, Tomato, puree-Cooked; Dried; Boiled15003240, 211, 2, 0.00%, Rice, brown-Cooked; Fresh or N/S; Baked15004010, 230, 3, 0.00%, Wheat, grain-Cooked; Dried; Cook Meth N/S 8002700, 232, 1, 0.00%, Pepper, bell-Cooked; Dried; Boiled 1010780, 212, 2, 0.00%, Carrot-Cooked; Fresh or N/S; Boiled21000470, 253, 3, 0.00%, Beef, fat-Cooked; Cured etc; Fried 4012480, 232, 1, 0.00%, Parsley, leaves-Cooked; Dried; Boiled11000110, 211, 1, 0.00%, Apple, sauce-Cooked; Fresh or N/S; Baked 6030400, 210, 2, 0.00%, Bean, navy, seed-Cooked; Fresh or N/S; Cook MethN/S 6030350, 210, 2, 0.00%, Bean, great northern, seed-Cooked; Fresh or N/S;Cook Meth N/S15001240, 230, 2, 0.00%, Corn, field, syrup-Cooked; Dried; Cook Meth N/S12002600, 120, 1, 0.00%, Peach-Uncooked; Frozen; Cook Meth N/S 6030340, 232, 1, 0.00%, Bean, cowpea, seed-Cooked; Dried; Boiled21000440, 250, 1, 0.00%, Beef, meat-Cooked; Cured etc; Cook Meth N/S15004040, 230, 3, 0.00%, Wheat, bran-Cooked; Dried; Cook Meth N/S15001270, 242, 1, 0.00%, Corn, sweet-Cooked; Canned; Boiled 8002720, 242, 1, 0.00%, Pepper, nonbell-Cooked; Canned; Boiled 1033000, 221, 2, 0.00%, Potato, tuber, w/o peel-Cooked; Frozen; Baked 6003470, 212, 2, 0.00%, Soybean, seed-Cooked; Fresh or N/S; Boiled26003390, 211, 2, 0.00%, Sheep, meat-Cooked; Fresh or N/S; Baked15004010, 232, 1, 0.00%, Wheat, grain-Cooked; Dried; Boiled15001241, 210, 1, 0.00%, Corn, field, syrup-babyfood-Cooked; Fresh or N/S;Cook Meth N/S

350

27002220, 213, 2, 0.00%, Milk, fat-Cooked; Fresh or N/S; Fried 1010781, 240, 1, 0.00%, Carrot-babyfood-Cooked; Canned; Cook Meth N/S21000470, 250, 1, 0.00%, Beef, fat-Cooked; Cured etc; Cook Meth N/S11000100, 120, 2, 0.00%, Apple, juice-Uncooked; Frozen; Cook Meth N/S15001210, 231, 2, 0.00%, Corn, field, meal-Cooked; Dried; Baked 9023080, 232, 1, 0.00%, Pumpkin-Cooked; Dried; Boiled15001240, 212, 2, 0.00%, Corn, field, syrup-Cooked; Fresh or N/S; Boiled95003600, 120, 1, 0.00%, Strawberry, juice-Uncooked; Frozen; Cook Meth N/S 6003481, 230, 2, 0.00%, Soybean, flour-babyfood-Cooked; Dried; Cook MethN/S25002930, 252, 1, 0.00%, Pork, fat-Cooked; Cured etc; Boiled15003240, 232, 1, 0.00%, Rice, brown-Cooked; Dried; Boiled15001230, 210, 1, 0.00%, Corn, field, starch-Cooked; Fresh or N/S; Cook MethN/S21000460, 212, 1, 0.00%, Beef, meat byproducts-Cooked; Fresh or N/S; Boiled95000730, 110, 1, 0.00%, Cactus-Uncooked; Fresh or N/S; Cook Meth N/S 8003771, 240, 1, 0.00%, Tomato, puree-babyfood-Cooked; Canned; Cook MethN/S95002790, 211, 1, 0.00%, Pineapple-Cooked; Fresh or N/S; Baked15001241, 110, 1, 0.00%, Corn, field, syrup-babyfood-Uncooked; Fresh or N/S;Cook Meth N/S15001210, 211, 1, 0.00%, Corn, field, meal-Cooked; Fresh or N/S; Baked20003640, 110, 1, 0.00%, Sunflower, seed-Uncooked; Fresh or N/S; Cook MethN/S 8003770, 215, 1, 0.00%, Tomato, puree-Cooked; Fresh or N/S; Boiled/baked11000080, 211, 1, 0.00%, Apple, peeled fruit-Cooked; Fresh or N/S; Baked 1010780, 110, 1, 0.00%, Carrot-Uncooked; Fresh or N/S; Cook Meth N/S25002900, 253, 1, 0.00%, Pork, meat-Cooked; Cured etc; Fried 9023571, 240, 1, 0.00%, Squash, winter-babyfood-Cooked; Canned; Cook MethN/S 6030360, 232, 1, 0.00%, Bean, kidney, seed-Cooked; Dried; Boiled26003410, 211, 1, 0.00%, Sheep, fat-Cooked; Fresh or N/S; Baked 5010690, 110, 1, 0.00%, Cabbage-Uncooked; Fresh or N/S; Cook Meth N/S15001270, 222, 1, 0.00%, Corn, sweet-Cooked; Frozen; Boiled25002900, 252, 1, 0.00%, Pork, meat-Cooked; Cured etc; Boiled15001260, 231, 1, 0.00%, Corn, pop-Cooked; Dried; Baked11002680, 120, 1, 0.00%, Pear, juice-Uncooked; Frozen; Cook Meth N/S 8003760, 212, 1, 0.00%, Tomato, paste-Cooked; Fresh or N/S; Boiled 1010500, 242, 1, 0.00%, Beet, garden, roots-Cooked; Canned; Boiled19012490, 212, 1, 0.00%, Parsley, dried leaves-Cooked; Fresh or N/S; Boiled10002010, 230, 1, 0.00%, Lemon, peel-Cooked; Dried; Cook Meth N/S25002920, 232, 1, 0.00%, Pork, meat byproducts-Cooked; Dried; Boiled10002420, 240, 1, 0.00%, Orange, peel-Cooked; Canned; Cook Meth N/S 1033001, 240, 1, 0.00%, Potato, tuber, w/o peel-babyfood-Cooked; Canned;Cook Meth N/S 6003481, 210, 1, 0.00%, Soybean, flour-babyfood-Cooked; Fresh or N/S; CookMeth N/S

Number of printed records = 15 Number of records represented = 44 (nf = number of foods/ff reported for this daily exposure amount (exceeding minimumcontribution) (nx = number of times this exposure amount was computed for the same person on thesame day.)

Demographic data for each record: Exposurecontribution data by food/ff consumed (NF lines): PID, HH-Indiv, Day,Sex, Age, Bw-kg, Nf, Nx, Tot Expos, Samplwt, Food, FF,Amt(g), Residue , Adj#1, Adj#2, Contributn, Percnt -----, --------, ---,---, ---, ------, --, ----, -----------, -------,--------, --,------, ----------, -----, -----, ----------, ------

18849 ,28906-01 , 1 ,F ,2Y , 11.36 , 1 , 1 , 0.0276204 , 10882 ,95002350,240, 40.8 , 7.490000 , 1.00 , 1.00 , 0.0268921 , 97.36

351

17362 ,21332-01 , 1 ,F ,3Y , 14.99 , 1 , 1 , 0.0273614 , 2245 ,13013200,110, 107.6 , 3.790000 , 1.00 , 1.00 , 0.0271945 , 99.39

18279 ,25865-03 , 1 ,M ,3Y , 14.99 , 1 , 1 , 0.0182944 , 1662 ,11000070,110, 552.0 , 0.490000 , 1.00 , 1.00 , 0.0180320 , 98.57

4445 ,39501-04 , 2 ,M ,4Y , 17.72 , 1 , 1 , 0.0175004 , 1109 ,12002620,110, 457.7 , 0.670000 , 1.00 , 1.00 , 0.0172995 , 98.85

4445 ,39501-04 , 2 ,M ,4Y , 17.72 , 1 , 1 , 0.0174928 , 1109 ,12002620,110, 457.7 , 0.670000 , 1.00 , 1.00 , 0.0172995 , 98.90

4445 ,39501-04 , 2 ,M ,4Y , 17.72 , 1 , 2 , 0.0174833 , 1109 ,12002620,110, 457.7 , 0.670000 , 1.00 , 1.00 , 0.0172995 , 98.95

4445 ,39501-04 , 2 ,M ,4Y , 17.72 , 1 , 15 , 0.0174552 , 1109 ,12002620,110, 457.7 , 0.670000 , 1.00 , 1.00 , 0.0172995 , 99.11

18849 ,28906-01 , 1 ,F ,2Y , 11.36 , 2 , 1 , 0.0150563 , 10882 ,10001810,240, 37.5 , 0.039000 , 1.00 , 2.10 , 0.0002702 , 1.79,,,,,,,,, ,95002350,240, 40.8 , 3.950000 , 1.00 , 1.00 , 0.0141821 , 94.19

18279 ,25865-03 , 2 ,M ,3Y , 14.99 , 2 , 1 , 0.0142804 , 1662 ,11000070,110, 424.0 , 0.490000 , 1.00 , 1.00 , 0.0138507 , 96.99,,,,,,,,, ,10002410,120, 498.0 , 0.009000 , 1.00 , 1.00 , 0.0002988 , 2.09

4446 ,39501-05 , 2 ,M ,2Y , 16.81 , 1 , 1 , 0.0138257 , 2290 ,12002620,110, 343.3 , 0.670000 , 1.00 , 1.00 , 0.0136760 , 98.92

4446 ,39501-05 , 2 ,M ,2Y , 16.81 , 1 , 2 , 0.0138183 , 2290 ,12002620,110, 343.3 , 0.670000 , 1.00 , 1.00 , 0.0136760 , 98.97

4446 ,39501-05 , 2 ,M ,2Y , 16.81 , 1 , 2 , 0.0138125 , 2290 ,12002620,110, 343.3 , 0.670000 , 1.00 , 1.00 , 0.0136760 , 99.01

4446 ,39501-05 , 2 ,M ,2Y , 16.81 , 1 , 1 , 0.0138109 , 2290 ,12002620,110, 343.3 , 0.670000 , 1.00 , 1.00 , 0.0136760 , 99.02

4446 ,39501-05 , 2 ,M ,2Y , 16.81 , 1 , 13 , 0.0138034 , 2290 ,12002620,110, 343.3 , 0.670000 , 1.00 , 1.00 , 0.0136760 , 99.08

18777 ,28851-01 , 1 ,M ,3Y , 12.27 , 2 , 1 , 0.0137843 , 794 ,11000070,110, 69.0 , 0.041000 , 1.00 , 1.00 , 0.0002305 , 1.67,,,,,,,,, ,95001750,110, 322.8 , 0.510000 , 1.00 , 1.00 , 0.0134125 , 97.30

================================================================================Non-hispanic whitesLow percentile for CEC records: 95 Exposure (mg/day) = 0.000391High percentile for CEC records: 100 Exposure (mg/day) = 0.236331Number of actual records in this interval: 41469

Critical foods/foodforms for this population (as derived from these records): N=number of appearances in all records (including duplicates) %=percent of total exposure for all records (including duplicates)

Food, FF, N , Percent, Food Name --------, ---, -----, -------, -------------12000910, 210, 8266, 8.58%, Cherry, juice-Cooked; Fresh or N/S; Cook Meth N/S

352

12002880, 110, 1488, 7.69%, Plum, prune, juice-Uncooked; Fresh or N/S; CookMeth N/S10002000, 110, 4797, 4.50%, Lemon, juice-Uncooked; Fresh or N/S; Cook Meth N/S12000910, 110, 457, 3.74%, Cherry, juice-Uncooked; Fresh or N/S; Cook Meth N/S 4023220, 240, 152, 2.78%, Rhubarb-Cooked; Canned; Cook Meth N/S11000070, 110, 1636, 2.56%, Apple, fruit with peel-Uncooked; Fresh or N/S; CookMeth N/S10001810, 110, 2365, 2.42%, Grapefruit, juice-Uncooked; Fresh or N/S; Cook MethN/S13021910, 110, 19, 2.42%, Huckleberry-Uncooked; Fresh or N/S; Cook Meth N/S12002610, 130, 380, 2.28%, Peach, dried-Uncooked; Dried; Cook Meth N/S95002810, 110, 2284, 2.24%, Pineapple, juice-Uncooked; Fresh or N/S; Cook MethN/S 4023220, 211, 418, 1.99%, Rhubarb-Cooked; Fresh or N/S; Baked10002000, 210, 8360, 1.94%, Lemon, juice-Cooked; Fresh or N/S; Cook Meth N/S95002810, 240, 5883, 1.94%, Pineapple, juice-Cooked; Canned; Cook Meth N/S10003690, 110, 1281, 1.94%, Tangerine-Uncooked; Fresh or N/S; Cook Meth N/S 8002720, 110, 1282, 1.86%, Pepper, nonbell-Uncooked; Fresh or N/S; Cook MethN/S 8002340, 210, 671, 1.75%, Okra-Cooked; Fresh or N/S; Cook Meth N/S 4023670, 212, 190, 1.70%, Swiss chard-Cooked; Fresh or N/S; Boiled 5022290, 212, 268, 1.55%, Mustard greens-Cooked; Fresh or N/S; Boiled12000911, 240, 760, 1.52%, Cherry, juice-babyfood-Cooked; Canned; Cook MethN/S95001750, 110, 601, 1.43%, Grape-Uncooked; Fresh or N/S; Cook Meth N/S13020570, 211, 571, 1.41%, Blueberry-Cooked; Fresh or N/S; Baked11000100, 110, 5010, 1.26%, Apple, juice-Uncooked; Fresh or N/S; Cook Meth N/S13020570, 110, 434, 1.19%, Blueberry-Uncooked; Fresh or N/S; Cook Meth N/S 8002720, 210, 1842, 1.09%, Pepper, nonbell-Cooked; Fresh or N/S; Cook Meth N/S10003700, 240, 4035, 0.88%, Tangerine, juice-Cooked; Canned; Cook Meth N/S11000090, 211, 1651, 0.85%, Apple, dried-Cooked; Fresh or N/S; Baked10002000, 130, 1411, 0.81%, Lemon, juice-Uncooked; Dried; Cook Meth N/S11000090, 130, 438, 0.79%, Apple, dried-Uncooked; Dried; Cook Meth N/S13013200, 240, 553, 0.77%, Raspberry-Cooked; Canned; Cook Meth N/S12002620, 110, 247, 0.69%, Peach, juice-Uncooked; Fresh or N/S; Cook Meth N/S10002000, 240, 4140, 0.68%, Lemon, juice-Cooked; Canned; Cook Meth N/S12002881, 240, 190, 0.67%, Plum, prune, juice-babyfood-Cooked; Canned; CookMeth N/S 8002340, 220, 266, 0.67%, Okra-Cooked; Frozen; Cook Meth N/S95002350, 240, 175, 0.65%, Olive-Cooked; Canned; Cook Meth N/S10002070, 110, 780, 0.64%, Lime, juice-Uncooked; Fresh or N/S; Cook Meth N/S 8002340, 213, 472, 0.63%, Okra-Cooked; Fresh or N/S; Fried95001760, 240, 4739, 0.59%, Grape, juice-Cooked; Canned; Cook Meth N/S12002600, 240, 586, 0.59%, Peach-Cooked; Canned; Cook Meth N/S13010580, 240, 3856, 0.57%, Boysenberry-Cooked; Canned; Cook Meth N/S27002220, 110, 14648, 0.53%, Milk, fat-Uncooked; Fresh or N/S; Cook Meth N/S10002070, 240, 3430, 0.53%, Lime, juice-Cooked; Canned; Cook Meth N/S 9010800, 110, 76, 0.52%, Casaba-Uncooked; Fresh or N/S; Cook Meth N/S 4020860, 110, 95, 0.52%, Celery, juice-Uncooked; Fresh or N/S; Cook Meth N/S12002601, 240, 230, 0.51%, Peach-babyfood-Cooked; Canned; Cook Meth N/S15003251, 230, 1453, 0.51%, Rice, flour-babyfood-Cooked; Dried; Cook Meth N/S25002930, 210, 5502, 0.50%, Pork, fat-Cooked; Fresh or N/S; Cook Meth N/S13020571, 240, 103, 0.49%, Blueberry-babyfood-Cooked; Canned; Cook Meth N/S95001760, 110, 1917, 0.48%, Grape, juice-Uncooked; Fresh or N/S; Cook Meth N/S 5020700, 210, 365, 0.47%, Cabbage, Chinese, bok choy-Cooked; Fresh or N/S;Cook Meth N/S13010580, 120, 1031, 0.47%, Boysenberry-Uncooked; Frozen; Cook Meth N/S12000910, 240, 2361, 0.46%, Cherry, juice-Cooked; Canned; Cook Meth N/S12002600, 110, 343, 0.42%, Peach-Uncooked; Fresh or N/S; Cook Meth N/S 8002720, 213, 457, 0.41%, Pepper, nonbell-Cooked; Fresh or N/S; Fried11000110, 212, 1359, 0.38%, Apple, sauce-Cooked; Fresh or N/S; Boiled95002811, 240, 845, 0.36%, Pineapple, juice-babyfood-Cooked; Canned; Cook MethN/S10002000, 120, 1122, 0.35%, Lemon, juice-Uncooked; Frozen; Cook Meth N/S95002810, 120, 1113, 0.34%, Pineapple, juice-Uncooked; Frozen; Cook Meth N/S

353

15001240, 240, 10637, 0.34%, Corn, field, syrup-Cooked; Canned; Cook Meth N/S11002670, 130, 361, 0.33%, Pear, dried-Uncooked; Dried; Cook Meth N/S10001810, 240, 2564, 0.33%, Grapefruit, juice-Cooked; Canned; Cook Meth N/S 8002720, 240, 1346, 0.33%, Pepper, nonbell-Cooked; Canned; Cook Meth N/S 5022290, 242, 77, 0.32%, Mustard greens-Cooked; Canned; Boiled 4023220, 120, 38, 0.32%, Rhubarb-Uncooked; Frozen; Cook Meth N/S13013200, 110, 401, 0.30%, Raspberry-Uncooked; Fresh or N/S; Cook Meth N/S13010550, 240, 495, 0.27%, Blackberry-Cooked; Canned; Cook Meth N/S25002930, 213, 2163, 0.27%, Pork, fat-Cooked; Fresh or N/S; Fried15003250, 230, 2183, 0.27%, Rice, flour-Cooked; Dried; Cook Meth N/S 8002700, 210, 318, 0.26%, Pepper, bell-Cooked; Fresh or N/S; Cook Meth N/S10002410, 110, 3915, 0.26%, Orange, juice-Uncooked; Fresh or N/S; Cook Meth N/S11000111, 240, 671, 0.26%, Apple, sauce-babyfood-Cooked; Canned; Cook Meth N/S15004020, 211, 11013, 0.26%, Wheat, flour-Cooked; Fresh or N/S; Baked 5020700, 150, 133, 0.25%, Cabbage, Chinese, bok choy-Uncooked; Cured etc;Cook Meth N/S25002930, 250, 2969, 0.25%, Pork, fat-Cooked; Cured etc; Cook Meth N/S11002660, 110, 133, 0.25%, Pear-Uncooked; Fresh or N/S; Cook Meth N/S 8002730, 210, 1815, 0.24%, Pepper, nonbell, dried-Cooked; Fresh or N/S; CookMeth N/S11000100, 240, 2890, 0.24%, Apple, juice-Cooked; Canned; Cook Meth N/S10002070, 120, 1286, 0.23%, Lime, juice-Uncooked; Frozen; Cook Meth N/S 8002700, 110, 283, 0.23%, Pepper, bell-Uncooked; Fresh or N/S; Cook Meth N/S 8002340, 150, 96, 0.23%, Okra-Uncooked; Cured etc; Cook Meth N/S 5022290, 222, 38, 0.22%, Mustard greens-Cooked; Frozen; Boiled11002661, 240, 90, 0.22%, Pear-babyfood-Cooked; Canned; Cook Meth N/S13013210, 110, 60, 0.21%, Raspberry, juice-Uncooked; Fresh or N/S; Cook MethN/S13010580, 110, 229, 0.21%, Boysenberry-Uncooked; Fresh or N/S; Cook Meth N/S10001810, 120, 917, 0.21%, Grapefruit, juice-Uncooked; Frozen; Cook Meth N/S10003700, 110, 343, 0.20%, Tangerine, juice-Uncooked; Fresh or N/S; Cook MethN/S11000090, 230, 780, 0.20%, Apple, dried-Cooked; Dried; Cook Meth N/S10003700, 120, 965, 0.20%, Tangerine, juice-Uncooked; Frozen; Cook Meth N/S11002660, 240, 146, 0.20%, Pear-Cooked; Canned; Cook Meth N/S11000101, 240, 1190, 0.17%, Apple, juice-babyfood-Cooked; Canned; Cook Meth N/S95002350, 211, 119, 0.17%, Olive-Cooked; Fresh or N/S; Baked 8002730, 212, 1306, 0.17%, Pepper, nonbell, dried-Cooked; Fresh or N/S; Boiled25002930, 211, 2494, 0.16%, Pork, fat-Cooked; Fresh or N/S; Baked25002930, 253, 1799, 0.16%, Pork, fat-Cooked; Cured etc; Fried95003590, 110, 179, 0.16%, Strawberry-Uncooked; Fresh or N/S; Cook Meth N/S13013200, 120, 73, 0.15%, Raspberry-Uncooked; Frozen; Cook Meth N/S12000900, 110, 280, 0.15%, Cherry-Uncooked; Fresh or N/S; Cook Meth N/S 8002720, 150, 241, 0.15%, Pepper, nonbell-Uncooked; Cured etc; Cook Meth N/S11000081, 240, 112, 0.15%, Apple, peeled fruit-babyfood-Cooked; Canned; CookMeth N/S95001750, 210, 379, 0.14%, Grape-Cooked; Fresh or N/S; Cook Meth N/S15003251, 240, 968, 0.13%, Rice, flour-babyfood-Cooked; Canned; Cook Meth N/S11000091, 230, 183, 0.13%, Apple, dried-babyfood-Cooked; Dried; Cook Meth N/S21000470, 210, 4241, 0.12%, Beef, fat-Cooked; Fresh or N/S; Cook Meth N/S12002621, 240, 76, 0.12%, Peach, juice-babyfood-Cooked; Canned; Cook Meth N/S95002800, 130, 362, 0.11%, Pineapple, dried-Uncooked; Dried; Cook Meth N/S13020570, 214, 50, 0.11%, Blueberry-Cooked; Fresh or N/S; Fried/baked13021360, 110, 57, 0.11%, Currant-Uncooked; Fresh or N/S; Cook Meth N/S10002410, 120, 1791, 0.11%, Orange, juice-Uncooked; Frozen; Cook Meth N/S12002620, 240, 98, 0.11%, Peach, juice-Cooked; Canned; Cook Meth N/S 5020700, 110, 57, 0.11%, Cabbage, Chinese, bok choy-Uncooked; Fresh or N/S;Cook Meth N/S25002900, 250, 2469, 0.10%, Pork, meat-Cooked; Cured etc; Cook Meth N/S10002001, 240, 424, 0.10%, Lemon, juice-babyfood-Cooked; Canned; Cook Meth N/S21000440, 210, 3640, 0.10%, Beef, meat-Cooked; Fresh or N/S; Cook Meth N/S95003600, 240, 189, 0.10%, Strawberry, juice-Cooked; Canned; Cook Meth N/S12000121, 240, 208, 0.10%, Apricot-babyfood-Cooked; Canned; Cook Meth N/S15001240, 110, 4310, 0.10%, Corn, field, syrup-Uncooked; Fresh or N/S; CookMeth N/S

354

13020570, 120, 118, 0.10%, Blueberry-Uncooked; Frozen; Cook Meth N/S12000900, 211, 97, 0.09%, Cherry-Cooked; Fresh or N/S; Baked 6010430, 242, 112, 0.09%, Bean, snap, succulent-Cooked; Canned; Boiled12002300, 110, 64, 0.09%, Nectarine-Uncooked; Fresh or N/S; Cook Meth N/S 8002720, 220, 19, 0.09%, Pepper, nonbell-Cooked; Frozen; Cook Meth N/S13013201, 240, 68, 0.08%, Raspberry-babyfood-Cooked; Canned; Cook Meth N/S 9010750, 110, 212, 0.08%, Cantaloupe-Uncooked; Fresh or N/S; Cook Meth N/S 8003770, 240, 1955, 0.07%, Tomato, puree-Cooked; Canned; Cook Meth N/S11002660, 210, 252, 0.07%, Pear-Cooked; Fresh or N/S; Cook Meth N/S12000910, 120, 881, 0.07%, Cherry, juice-Uncooked; Frozen; Cook Meth N/S15004020, 232, 2650, 0.07%, Wheat, flour-Cooked; Dried; Boiled11002681, 240, 19, 0.07%, Pear, juice-babyfood-Cooked; Canned; Cook Meth N/S95002360, 900, 873, 0.07%, Olive, oil-Refined; FF N/A; Cook Meth N/S12000141, 240, 88, 0.07%, Apricot, juice-babyfood-Cooked; Canned; Cook MethN/S25002900, 211, 893, 0.07%, Pork, meat-Cooked; Fresh or N/S; Baked13010550, 110, 33, 0.07%, Blackberry-Uncooked; Fresh or N/S; Cook Meth N/S95003590, 240, 83, 0.06%, Strawberry-Cooked; Canned; Cook Meth N/S 8002720, 221, 81, 0.06%, Pepper, nonbell-Cooked; Frozen; Baked13010550, 211, 18, 0.06%, Blackberry-Cooked; Fresh or N/S; Baked 8002730, 240, 981, 0.06%, Pepper, nonbell, dried-Cooked; Canned; Cook MethN/S10001070, 110, 58, 0.06%, Citrus hybrids-Uncooked; Fresh or N/S; Cook MethN/S11000080, 211, 51, 0.06%, Apple, peeled fruit-Cooked; Fresh or N/S; Baked 8002720, 215, 236, 0.06%, Pepper, nonbell-Cooked; Fresh or N/S; Boiled/baked15003250, 210, 739, 0.06%, Rice, flour-Cooked; Fresh or N/S; Cook Meth N/S10002000, 211, 742, 0.06%, Lemon, juice-Cooked; Fresh or N/S; Baked95001761, 240, 240, 0.06%, Grape, juice-babyfood-Cooked; Canned; Cook Meth N/S27002220, 120, 2242, 0.05%, Milk, fat-Uncooked; Frozen; Cook Meth N/S11000100, 120, 237, 0.05%, Apple, juice-Uncooked; Frozen; Cook Meth N/S15001210, 233, 1688, 0.05%, Corn, field, meal-Cooked; Dried; Fried25002900, 210, 1391, 0.05%, Pork, meat-Cooked; Fresh or N/S; Cook Meth N/S13021370, 130, 19, 0.05%, Currant, dried-Uncooked; Dried; Cook Meth N/S13013200, 211, 130, 0.05%, Raspberry-Cooked; Fresh or N/S; Baked21000440, 211, 1427, 0.05%, Beef, meat-Cooked; Fresh or N/S; Baked 4011500, 110, 582, 0.05%, Endive-Uncooked; Fresh or N/S; Cook Meth N/S 4012480, 210, 1070, 0.05%, Parsley, leaves-Cooked; Fresh or N/S; Cook Meth N/S95001760, 120, 119, 0.05%, Grape, juice-Uncooked; Frozen; Cook Meth N/S15001240, 130, 1664, 0.04%, Corn, field, syrup-Uncooked; Dried; Cook Meth N/S13020570, 213, 34, 0.04%, Blueberry-Cooked; Fresh or N/S; Fried13020570, 210, 33, 0.04%, Blueberry-Cooked; Fresh or N/S; Cook Meth N/S12000120, 240, 120, 0.04%, Apricot-Cooked; Canned; Cook Meth N/S 8002720, 212, 446, 0.04%, Pepper, nonbell-Cooked; Fresh or N/S; Boiled10002400, 110, 84, 0.04%, Orange-Uncooked; Fresh or N/S; Cook Meth N/S12000901, 240, 34, 0.04%, Cherry-babyfood-Cooked; Canned; Cook Meth N/S95000230, 110, 1938, 0.04%, Banana-Uncooked; Fresh or N/S; Cook Meth N/S15004020, 210, 1750, 0.04%, Wheat, flour-Cooked; Fresh or N/S; Cook Meth N/S95002640, 210, 1860, 0.04%, Peanut, butter-Cooked; Fresh or N/S; Cook Meth N/S 8003770, 210, 950, 0.04%, Tomato, puree-Cooked; Fresh or N/S; Cook Meth N/S95001750, 240, 116, 0.04%, Grape-Cooked; Canned; Cook Meth N/S13013210, 240, 154, 0.04%, Raspberry, juice-Cooked; Canned; Cook Meth N/S 8002340, 212, 115, 0.04%, Okra-Cooked; Fresh or N/S; Boiled 6010430, 212, 38, 0.04%, Bean, snap, succulent-Cooked; Fresh or N/S; Boiled15001200, 230, 1357, 0.04%, Corn, field, flour-Cooked; Dried; Cook Meth N/S10002410, 240, 1239, 0.04%, Orange, juice-Cooked; Canned; Cook Meth N/S 8002340, 222, 19, 0.04%, Okra-Cooked; Frozen; Boiled 8002720, 230, 114, 0.04%, Pepper, nonbell-Cooked; Dried; Cook Meth N/S21000440, 213, 1474, 0.03%, Beef, meat-Cooked; Fresh or N/S; Fried25002930, 230, 388, 0.03%, Pork, fat-Cooked; Dried; Cook Meth N/S25002930, 240, 252, 0.03%, Pork, fat-Cooked; Canned; Cook Meth N/S15001210, 230, 1346, 0.03%, Corn, field, meal-Cooked; Dried; Cook Meth N/S25002900, 213, 1007, 0.03%, Pork, meat-Cooked; Fresh or N/S; Fried95003600, 210, 217, 0.03%, Strawberry, juice-Cooked; Fresh or N/S; Cook MethN/S

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12002610, 230, 38, 0.03%, Peach, dried-Cooked; Dried; Cook Meth N/S10002000, 212, 86, 0.03%, Lemon, juice-Cooked; Fresh or N/S; Boiled 8002340, 240, 25, 0.03%, Okra-Cooked; Canned; Cook Meth N/S 8002700, 211, 113, 0.03%, Pepper, bell-Cooked; Fresh or N/S; Baked21000470, 213, 1378, 0.03%, Beef, fat-Cooked; Fresh or N/S; Fried13013210, 120, 60, 0.03%, Raspberry, juice-Uncooked; Frozen; Cook Meth N/S 6003490, 210, 158, 0.03%, Soybean, soy milk-Cooked; Fresh or N/S; Cook MethN/S 6010431, 240, 30, 0.03%, Bean, snap, succulent-babyfood-Cooked; Canned; CookMeth N/S13020570, 240, 119, 0.03%, Blueberry-Cooked; Canned; Cook Meth N/S15004020, 231, 1050, 0.03%, Wheat, flour-Cooked; Dried; Baked12000120, 110, 13, 0.03%, Apricot-Uncooked; Fresh or N/S; Cook Meth N/S13010561, 240, 30, 0.03%, Blackberry, juice-babyfood-Cooked; Canned; CookMeth N/S 9021350, 110, 189, 0.02%, Cucumber-Uncooked; Fresh or N/S; Cook Meth N/S13010580, 210, 19, 0.02%, Boysenberry-Cooked; Fresh or N/S; Cook Meth N/S 8002700, 213, 41, 0.02%, Pepper, bell-Cooked; Fresh or N/S; Fried95002790, 240, 512, 0.02%, Pineapple-Cooked; Canned; Cook Meth N/S 1030821, 240, 549, 0.02%, Cassava-babyfood-Cooked; Canned; Cook Meth N/S27002220, 232, 816, 0.02%, Milk, fat-Cooked; Dried; Boiled25002930, 212, 437, 0.02%, Pork, fat-Cooked; Fresh or N/S; Boiled 8003760, 210, 832, 0.02%, Tomato, paste-Cooked; Fresh or N/S; Cook Meth N/S 9021350, 240, 192, 0.02%, Cucumber-Cooked; Canned; Cook Meth N/S95003590, 120, 10, 0.02%, Strawberry-Uncooked; Frozen; Cook Meth N/S21000440, 212, 689, 0.02%, Beef, meat-Cooked; Fresh or N/S; Boiled13010550, 120, 57, 0.02%, Blackberry-Uncooked; Frozen; Cook Meth N/S 8003770, 212, 510, 0.02%, Tomato, puree-Cooked; Fresh or N/S; Boiled15001241, 230, 302, 0.02%, Corn, field, syrup-babyfood-Cooked; Dried; CookMeth N/S21000470, 211, 785, 0.02%, Beef, fat-Cooked; Fresh or N/S; Baked15001260, 230, 813, 0.02%, Corn, pop-Cooked; Dried; Cook Meth N/S12000130, 130, 62, 0.02%, Apricot, dried-Uncooked; Dried; Cook Meth N/S12000900, 120, 46, 0.02%, Cherry-Uncooked; Frozen; Cook Meth N/S15001231, 240, 630, 0.02%, Corn, field, starch-babyfood-Cooked; Canned; CookMeth N/S95001320, 240, 396, 0.02%, Cranberry, juice-Cooked; Canned; Cook Meth N/S27002220, 211, 820, 0.02%, Milk, fat-Cooked; Fresh or N/S; Baked10001990, 110, 241, 0.02%, Lemon-Uncooked; Fresh or N/S; Cook Meth N/S12002600, 211, 25, 0.02%, Peach-Cooked; Fresh or N/S; Baked12000900, 240, 115, 0.02%, Cherry-Cooked; Canned; Cook Meth N/S 1033000, 212, 143, 0.02%, Potato, tuber, w/o peel-Cooked; Fresh or N/S;Boiled15001240, 120, 861, 0.02%, Corn, field, syrup-Uncooked; Frozen; Cook Meth N/S20003651, 900, 564, 0.02%, Sunflower, oil-babyfood-Refined; FF N/A; Cook MethN/S12000130, 211, 88, 0.02%, Apricot, dried-Cooked; Fresh or N/S; Baked 6010430, 222, 17, 0.02%, Bean, snap, succulent-Cooked; Frozen; Boiled15001241, 130, 221, 0.02%, Corn, field, syrup-babyfood-Uncooked; Dried; CookMeth N/S12002600, 120, 34, 0.02%, Peach-Uncooked; Frozen; Cook Meth N/S13013211, 240, 9, 0.02%, Raspberry, juice-babyfood-Cooked; Canned; Cook MethN/S15004020, 212, 610, 0.02%, Wheat, flour-Cooked; Fresh or N/S; Boiled10002060, 110, 63, 0.01%, Lime-Uncooked; Fresh or N/S; Cook Meth N/S27002220, 210, 594, 0.01%, Milk, fat-Cooked; Fresh or N/S; Cook Meth N/S11002680, 240, 56, 0.01%, Pear, juice-Cooked; Canned; Cook Meth N/S15004020, 213, 789, 0.01%, Wheat, flour-Cooked; Fresh or N/S; Fried11000080, 240, 4, 0.01%, Apple, peeled fruit-Cooked; Canned; Cook Meth N/S 8002700, 222, 13, 0.01%, Pepper, bell-Cooked; Frozen; Boiled27002220, 215, 503, 0.01%, Milk, fat-Cooked; Fresh or N/S; Boiled/baked15004010, 211, 680, 0.01%, Wheat, grain-Cooked; Fresh or N/S; Baked11000110, 210, 40, 0.01%, Apple, sauce-Cooked; Fresh or N/S; Cook Meth N/S 1010790, 240, 204, 0.01%, Carrot, juice-Cooked; Canned; Cook Meth N/S12002850, 110, 33, 0.01%, Plum-Uncooked; Fresh or N/S; Cook Meth N/S

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2001010, 110, 379, 0.01%, Chicory, tops-Uncooked; Fresh or N/S; Cook Meth N/S12002851, 240, 28, 0.01%, Plum-babyfood-Cooked; Canned; Cook Meth N/S 8003790, 240, 118, 0.01%, Tomato, juice-Cooked; Canned; Cook Meth N/S21000470, 212, 492, 0.01%, Beef, fat-Cooked; Fresh or N/S; Boiled21000441, 240, 309, 0.01%, Beef, meat-babyfood-Cooked; Canned; Cook Meth N/S 8002720, 232, 154, 0.01%, Pepper, nonbell-Cooked; Dried; Boiled 1033661, 240, 153, 0.01%, Sweet potato-babyfood-Cooked; Canned; Cook Meth N/S13020570, 230, 7, 0.01%, Blueberry-Cooked; Dried; Cook Meth N/S15004020, 215, 457, 0.01%, Wheat, flour-Cooked; Fresh or N/S; Boiled/baked95001760, 210, 244, 0.01%, Grape, juice-Cooked; Fresh or N/S; Cook Meth N/S 8002720, 211, 55, 0.01%, Pepper, nonbell-Cooked; Fresh or N/S; Baked95003590, 211, 24, 0.01%, Strawberry-Cooked; Fresh or N/S; Baked 8002730, 213, 221, 0.01%, Pepper, nonbell, dried-Cooked; Fresh or N/S; Fried27002220, 212, 426, 0.01%, Milk, fat-Cooked; Fresh or N/S; Boiled11000070, 211, 9, 0.01%, Apple, fruit with peel-Cooked; Fresh or N/S; Baked25002900, 253, 274, 0.01%, Pork, meat-Cooked; Cured etc; Fried15004010, 230, 355, 0.01%, Wheat, grain-Cooked; Dried; Cook Meth N/S21000470, 240, 269, 0.01%, Beef, fat-Cooked; Canned; Cook Meth N/S14002820, 211, 123, 0.01%, Pistachio-Cooked; Fresh or N/S; Baked15004020, 214, 373, 0.01%, Wheat, flour-Cooked; Fresh or N/S; Fried/baked12000140, 240, 49, 0.01%, Apricot, juice-Cooked; Canned; Cook Meth N/S15001241, 240, 184, 0.01%, Corn, field, syrup-babyfood-Cooked; Canned; CookMeth N/S25002930, 232, 123, 0.01%, Pork, fat-Cooked; Dried; Boiled 4013551, 240, 8, 0.01%, Spinach-babyfood-Cooked; Canned; Cook Meth N/S 8003790, 212, 72, 0.01%, Tomato, juice-Cooked; Fresh or N/S; Boiled10002000, 232, 50, 0.01%, Lemon, juice-Cooked; Dried; Boiled 8002730, 232, 290, 0.01%, Pepper, nonbell, dried-Cooked; Dried; Boiled11002680, 110, 13, 0.01%, Pear, juice-Uncooked; Fresh or N/S; Cook Meth N/S 4012480, 212, 108, 0.01%, Parsley, leaves-Cooked; Fresh or N/S; Boiled 9011870, 110, 25, 0.01%, Honeydew melon-Uncooked; Fresh or N/S; Cook MethN/S12000120, 211, 3, 0.01%, Apricot-Cooked; Fresh or N/S; Baked95000190, 212, 53, 0.01%, Asparagus-Cooked; Fresh or N/S; Boiled95002350, 210, 10, 0.01%, Olive-Cooked; Fresh or N/S; Cook Meth N/S95000730, 110, 23, 0.01%, Cactus-Uncooked; Fresh or N/S; Cook Meth N/S14002820, 110, 19, 0.01%, Pistachio-Uncooked; Fresh or N/S; Cook Meth N/S 8002700, 215, 26, 0.01%, Pepper, bell-Cooked; Fresh or N/S; Boiled/baked11000090, 210, 23, 0.01%, Apple, dried-Cooked; Fresh or N/S; Cook Meth N/S15001231, 130, 165, 0.01%, Corn, field, starch-babyfood-Uncooked; Dried; CookMeth N/S95003600, 110, 9, 0.01%, Strawberry, juice-Uncooked; Fresh or N/S; Cook MethN/S15001240, 210, 279, 0.01%, Corn, field, syrup-Cooked; Fresh or N/S; Cook MethN/S15004020, 240, 328, 0.01%, Wheat, flour-Cooked; Canned; Cook Meth N/S 4012480, 110, 67, 0.01%, Parsley, leaves-Uncooked; Fresh or N/S; Cook MethN/S 8003760, 212, 230, 0.01%, Tomato, paste-Cooked; Fresh or N/S; Boiled27002220, 213, 277, 0.01%, Milk, fat-Cooked; Fresh or N/S; Fried15003240, 232, 152, 0.01%, Rice, brown-Cooked; Dried; Boiled15001240, 211, 309, 0.01%, Corn, field, syrup-Cooked; Fresh or N/S; Baked 8002700, 150, 19, 0.01%, Pepper, bell-Uncooked; Cured etc; Cook Meth N/S 8002700, 221, 13, 0.00%, Pepper, bell-Cooked; Frozen; Baked25002931, 240, 104, 0.00%, Pork, fat-babyfood-Cooked; Canned; Cook Meth N/S95002790, 110, 106, 0.00%, Pineapple-Uncooked; Fresh or N/S; Cook Meth N/S13021370, 211, 20, 0.00%, Currant, dried-Cooked; Fresh or N/S; Baked95002630, 211, 119, 0.00%, Peanut-Cooked; Fresh or N/S; Baked19011440, 240, 182, 0.00%, Dillweed-Cooked; Canned; Cook Meth N/S12002861, 240, 12, 0.00%, Plum, prune, fresh-babyfood-Cooked; Canned; CookMeth N/S13010560, 110, 3, 0.00%, Blackberry, juice-Uncooked; Fresh or N/S; Cook MethN/S27022240, 110, 319, 0.00%, Milk, water-Uncooked; Fresh or N/S; Cook Meth N/S 5010690, 110, 226, 0.00%, Cabbage-Uncooked; Fresh or N/S; Cook Meth N/S

357

15001240, 230, 122, 0.00%, Corn, field, syrup-Cooked; Dried; Cook Meth N/S12000140, 110, 1, 0.00%, Apricot, juice-Uncooked; Fresh or N/S; Cook MethN/S15001260, 231, 70, 0.00%, Corn, pop-Cooked; Dried; Baked25002900, 240, 149, 0.00%, Pork, meat-Cooked; Canned; Cook Meth N/S15004020, 230, 192, 0.00%, Wheat, flour-Cooked; Dried; Cook Meth N/S15003250, 120, 108, 0.00%, Rice, flour-Uncooked; Frozen; Cook Meth N/S25002900, 212, 81, 0.00%, Pork, meat-Cooked; Fresh or N/S; Boiled12000120, 232, 3, 0.00%, Apricot-Cooked; Dried; Boiled25002930, 221, 43, 0.00%, Pork, fat-Cooked; Frozen; Baked21000470, 250, 86, 0.00%, Beef, fat-Cooked; Cured etc; Cook Meth N/S15001200, 210, 166, 0.00%, Corn, field, flour-Cooked; Fresh or N/S; Cook MethN/S11000080, 110, 3, 0.00%, Apple, peeled fruit-Uncooked; Fresh or N/S; CookMeth N/S 1010790, 110, 43, 0.00%, Carrot, juice-Uncooked; Fresh or N/S; Cook Meth N/S25002901, 240, 68, 0.00%, Pork, meat-babyfood-Cooked; Canned; Cook Meth N/S11000100, 210, 144, 0.00%, Apple, juice-Cooked; Fresh or N/S; Cook Meth N/S15001230, 210, 130, 0.00%, Corn, field, starch-Cooked; Fresh or N/S; Cook MethN/S15001210, 231, 179, 0.00%, Corn, field, meal-Cooked; Dried; Baked15001210, 211, 177, 0.00%, Corn, field, meal-Cooked; Fresh or N/S; Baked21000440, 240, 184, 0.00%, Beef, meat-Cooked; Canned; Cook Meth N/S95001320, 110, 67, 0.00%, Cranberry, juice-Uncooked; Fresh or N/S; Cook MethN/S15003250, 211, 83, 0.00%, Rice, flour-Cooked; Fresh or N/S; Baked 9023080, 211, 101, 0.00%, Pumpkin-Cooked; Fresh or N/S; Baked 1033660, 211, 60, 0.00%, Sweet potato-Cooked; Fresh or N/S; Baked95002810, 211, 67, 0.00%, Pineapple, juice-Cooked; Fresh or N/S; Baked 6030420, 210, 110, 0.00%, Bean, pinto, seed-Cooked; Fresh or N/S; Cook MethN/S15001210, 210, 105, 0.00%, Corn, field, meal-Cooked; Fresh or N/S; Cook MethN/S15001200, 214, 153, 0.00%, Corn, field, flour-Cooked; Fresh or N/S;Fried/baked27002220, 230, 83, 0.00%, Milk, fat-Cooked; Dried; Cook Meth N/S 8002700, 212, 12, 0.00%, Pepper, bell-Cooked; Fresh or N/S; Boiled 8003750, 110, 107, 0.00%, Tomato-Uncooked; Fresh or N/S; Cook Meth N/S12002600, 210, 5, 0.00%, Peach-Cooked; Fresh or N/S; Cook Meth N/S 6030420, 232, 122, 0.00%, Bean, pinto, seed-Cooked; Dried; Boiled 4020860, 240, 68, 0.00%, Celery, juice-Cooked; Canned; Cook Meth N/S10001990, 210, 26, 0.00%, Lemon-Cooked; Fresh or N/S; Cook Meth N/S26003390, 210, 61, 0.00%, Sheep, meat-Cooked; Fresh or N/S; Cook Meth N/S 6030420, 230, 138, 0.00%, Bean, pinto, seed-Cooked; Dried; Cook Meth N/S 1033000, 211, 56, 0.00%, Potato, tuber, w/o peel-Cooked; Fresh or N/S; Baked95000190, 242, 42, 0.00%, Asparagus-Cooked; Canned; Boiled27002220, 214, 82, 0.00%, Milk, fat-Cooked; Fresh or N/S; Fried/baked 5010830, 212, 72, 0.00%, Cauliflower-Cooked; Fresh or N/S; Boiled 9013990, 110, 56, 0.00%, Watermelon-Uncooked; Fresh or N/S; Cook Meth N/S15004040, 230, 132, 0.00%, Wheat, bran-Cooked; Dried; Cook Meth N/S14000810, 211, 33, 0.00%, Cashew-Cooked; Fresh or N/S; Baked21000440, 214, 84, 0.00%, Beef, meat-Cooked; Fresh or N/S; Fried/baked10002070, 212, 43, 0.00%, Lime, juice-Cooked; Fresh or N/S; Boiled20003640, 211, 22, 0.00%, Sunflower, seed-Cooked; Fresh or N/S; Baked 8003770, 211, 145, 0.00%, Tomato, puree-Cooked; Fresh or N/S; Baked10002010, 230, 60, 0.00%, Lemon, peel-Cooked; Dried; Cook Meth N/S15001200, 231, 79, 0.00%, Corn, field, flour-Cooked; Dried; Baked21000440, 250, 64, 0.00%, Beef, meat-Cooked; Cured etc; Cook Meth N/S11000070, 213, 2, 0.00%, Apple, fruit with peel-Cooked; Fresh or N/S; Fried10002071, 240, 47, 0.00%, Lime, juice-babyfood-Cooked; Canned; Cook Meth N/S15001200, 213, 78, 0.00%, Corn, field, flour-Cooked; Fresh or N/S; Fried 6003481, 230, 140, 0.00%, Soybean, flour-babyfood-Cooked; Dried; Cook MethN/S15003240, 210, 72, 0.00%, Rice, brown-Cooked; Fresh or N/S; Cook Meth N/S 8001480, 214, 9, 0.00%, Eggplant-Cooked; Fresh or N/S; Fried/baked

358

15001201, 230, 86, 0.00%, Corn, field, flour-babyfood-Cooked; Dried; CookMeth N/S14003910, 130, 42, 0.00%, Walnut-Uncooked; Dried; Cook Meth N/S21000471, 240, 81, 0.00%, Beef,fat-babyfood-Cooked; Canned; Cook Meth N/S 1032990, 212, 20, 0.00%, Potato, tuber, w/peel-Cooked; Fresh or N/S; Boiled 8002721, 240, 26, 0.00%, Pepper, nonbell-babyfood-Cooked; Canned; Cook MethN/S 8002730, 211, 72, 0.00%, Pepper, nonbell, dried-Cooked; Fresh or N/S; Baked 8003790, 110, 32, 0.00%, Tomato, juice-Uncooked; Fresh or N/S; Cook Meth N/S 8002730, 215, 19, 0.00%, Pepper, nonbell, dried-Cooked; Fresh or N/S;Boiled/baked20003640, 110, 57, 0.00%, Sunflower, seed-Uncooked; Fresh or N/S; Cook MethN/S10002411, 240, 44, 0.00%, Orange, juice-babyfood-Cooked; Canned; Cook MethN/S 8001480, 211, 3, 0.00%, Eggplant-Cooked; Fresh or N/S; Baked 9023090, 211, 38, 0.00%, Pumpkin, seed-Cooked; Fresh or N/S; Baked20003640, 230, 42, 0.00%, Sunflower, seed-Cooked; Dried; Cook Meth N/S 8003750, 212, 48, 0.00%, Tomato-Cooked; Fresh or N/S; Boiled25002920, 210, 96, 0.00%, Pork, meat byproducts-Cooked; Fresh or N/S; CookMeth N/S15001210, 232, 50, 0.00%, Corn, field, meal-Cooked; Dried; Boiled 8003750, 240, 43, 0.00%, Tomato-Cooked; Canned; Cook Meth N/S 9023080, 215, 19, 0.00%, Pumpkin-Cooked; Fresh or N/S; Boiled/baked 8002700, 214, 3, 0.00%, Pepper, bell-Cooked; Fresh or N/S; Fried/baked15001231, 110, 18, 0.00%, Corn, field, starch-babyfood-Uncooked; Fresh orN/S; Cook Meth N/S 8003770, 242, 22, 0.00%, Tomato, puree-Cooked; Canned; Boiled95002630, 210, 71, 0.00%, Peanut-Cooked; Fresh or N/S; Cook Meth N/S 6010430, 210, 1, 0.00%, Bean, snap, succulent-Cooked; Fresh or N/S; CookMeth N/S15004010, 232, 69, 0.00%, Wheat, grain-Cooked; Dried; Boiled15001240, 212, 74, 0.00%, Corn, field, syrup-Cooked; Fresh or N/S; Boiled21000470, 215, 19, 0.00%, Beef, fat-Cooked; Fresh or N/S; Boiled/baked11000070, 150, 2, 0.00%, Apple, fruit with peel-Uncooked; Cured etc; CookMeth N/S 8003790, 210, 31, 0.00%, Tomato, juice-Cooked; Fresh or N/S; Cook Meth N/S26003410, 210, 55, 0.00%, Sheep, fat-Cooked; Fresh or N/S; Cook Meth N/S 1010500, 250, 29, 0.00%, Beet, garden, roots-Cooked; Cured etc; Cook MethN/S 1032990, 211, 25, 0.00%, Potato, tuber, w/peel-Cooked; Fresh or N/S; Baked11002680, 120, 19, 0.00%, Pear, juice-Uncooked; Frozen; Cook Meth N/S 8002700, 240, 3, 0.00%, Pepper, bell-Cooked; Canned; Cook Meth N/S 8003740, 210, 58, 0.00%, Tomatillo-Cooked; Fresh or N/S; Cook Meth N/S12002870, 130, 11, 0.00%, Plum, prune, dried-Uncooked; Dried; Cook Meth N/S 8002730, 221, 22, 0.00%, Pepper, nonbell, dried-Cooked; Frozen; Baked 6010430, 240, 2, 0.00%, Bean, snap, succulent-Cooked; Canned; Cook Meth N/S21000440, 215, 19, 0.00%, Beef, meat-Cooked; Fresh or N/S; Boiled/baked95002350, 212, 1, 0.00%, Olive-Cooked; Fresh or N/S; Boiled 6030300, 232, 42, 0.00%, Bean, black, seed-Cooked; Dried; Boiled15001200, 211, 38, 0.00%, Corn, field, flour-Cooked; Fresh or N/S; Baked95001790, 110, 26, 0.00%, Grape, wine and sherry-Uncooked; Fresh or N/S; CookMeth N/S12000120, 213, 2, 0.00%, Apricot-Cooked; Fresh or N/S; Fried27002220, 242, 50, 0.00%, Milk, fat-Cooked; Canned; Boiled15004010, 231, 55, 0.00%, Wheat, grain-Cooked; Dried; Baked11000080, 213, 4, 0.00%, Apple, peeled fruit-Cooked; Fresh or N/S; Fried 4013550, 242, 3, 0.00%, Spinach-Cooked; Canned; Boiled15001260, 211, 40, 0.00%, Corn, pop-Cooked; Fresh or N/S; Baked 9023571, 240, 36, 0.00%, Squash, winter-babyfood-Cooked; Canned; Cook MethN/S25002930, 242, 46, 0.00%, Pork, fat-Cooked; Canned; Boiled20003640, 210, 30, 0.00%, Sunflower, seed-Cooked; Fresh or N/S; Cook Meth N/S 8002711, 240, 6, 0.00%, Pepper, bell, dried-babyfood-Cooked; Canned; CookMeth N/S

359

11000110, 240, 13, 0.00%, Apple, sauce-Cooked; Canned; Cook Meth N/S95001750, 120, 4, 0.00%, Grape-Uncooked; Frozen; Cook Meth N/S15003240, 230, 4, 0.00%, Rice, brown-Cooked; Dried; Cook Meth N/S15001210, 215, 18, 0.00%, Corn, field, meal-Cooked; Fresh or N/S;Boiled/baked15001270, 222, 8, 0.00%, Corn, sweet-Cooked; Frozen; Boiled 5010830, 222, 26, 0.00%, Cauliflower-Cooked; Frozen; Boiled95002791, 240, 26, 0.00%, Pineapple-babyfood-Cooked; Canned; Cook Meth N/S 6032030, 232, 28, 0.00%, Lentil, seed-Cooked; Dried; Boiled11000080, 221, 1, 0.00%, Apple, peeled fruit-Cooked; Frozen; Baked95002350, 221, 1, 0.00%, Olive-Cooked; Frozen; Baked25002930, 222, 20, 0.00%, Pork, fat-Cooked; Frozen; Boiled25002950, 210, 19, 0.00%, Pork, liver-Cooked; Fresh or N/S; Cook Meth N/S27002220, 221, 26, 0.00%, Milk, fat-Cooked; Frozen; Baked 8003760, 211, 61, 0.00%, Tomato, paste-Cooked; Fresh or N/S; Baked 6030400, 212, 21, 0.00%, Bean, navy, seed-Cooked; Fresh or N/S; Boiled25002920, 232, 21, 0.00%, Pork, meat byproducts-Cooked; Dried; Boiled25002900, 221, 23, 0.00%, Pork, meat-Cooked; Frozen; Baked21000440, 221, 21, 0.00%, Beef, meat-Cooked; Frozen; Baked15003240, 211, 30, 0.00%, Rice, brown-Cooked; Fresh or N/S; Baked20003650, 900, 31, 0.00%, Sunflower, oil-Refined; FF N/A; Cook Meth N/S21000470, 221, 20, 0.00%, Beef, fat-Cooked; Frozen; Baked15001210, 213, 23, 0.00%, Corn, field, meal-Cooked; Fresh or N/S; Fried10002420, 210, 19, 0.00%, Orange, peel-Cooked; Fresh or N/S; Cook Meth N/S14003910, 211, 30, 0.00%, Walnut-Cooked; Fresh or N/S; Baked 9023560, 212, 19, 0.00%, Squash, summer-Cooked; Fresh or N/S; Boiled10002420, 240, 19, 0.00%, Orange, peel-Cooked; Canned; Cook Meth N/S 1013140, 110, 22, 0.00%, Radish, roots-Uncooked; Fresh or N/S; Cook Meth N/S 6030340, 232, 19, 0.00%, Bean, cowpea, seed-Cooked; Dried; Boiled15004021, 211, 25, 0.00%, Wheat, flour-babyfood-Cooked; Fresh or N/S; Baked 9021350, 150, 16, 0.00%, Cucumber-Uncooked; Cured etc; Cook Meth N/S 1033660, 212, 13, 0.00%, Sweet potato-Cooked; Fresh or N/S; Boiled95002640, 240, 26, 0.00%, Peanut, butter-Cooked; Canned; Cook Meth N/S 1033000, 210, 11, 0.00%, Potato, tuber, w/o peel-Cooked; Fresh or N/S; CookMeth N/S15004021, 240, 39, 0.00%, Wheat, flour-babyfood-Cooked; Canned; Cook Meth N/S95003601, 240, 2, 0.00%, Strawberry, juice-babyfood-Cooked; Canned; CookMeth N/S 8003770, 221, 23, 0.00%, Tomato, puree-Cooked; Frozen; Baked95002630, 112, 21, 0.00%, Peanut-Uncooked; Fresh or N/S; Boiled 6030390, 232, 18, 0.00%, Bean, mung, seed-Cooked; Dried; Boiled 8003750, 211, 19, 0.00%, Tomato-Cooked; Fresh or N/S; Baked 8003750, 215, 19, 0.00%, Tomato-Cooked; Fresh or N/S; Boiled/baked 8003760, 242, 16, 0.00%, Tomato, paste-Cooked; Canned; Boiled15004020, 233, 31, 0.00%, Wheat, flour-Cooked; Dried; Fried 6003481, 240, 30, 0.00%, Soybean, flour-babyfood-Cooked; Canned; Cook MethN/S95002790, 211, 21, 0.00%, Pineapple-Cooked; Fresh or N/S; Baked 1033660, 242, 17, 0.00%, Sweet potato-Cooked; Canned; Boiled21000460, 210, 24, 0.00%, Beef, meat byproducts-Cooked; Fresh or N/S; CookMeth N/S14000810, 210, 25, 0.00%, Cashew-Cooked; Fresh or N/S; Cook Meth N/S14003910, 210, 25, 0.00%, Walnut-Cooked; Fresh or N/S; Cook Meth N/S12000140, 120, 5, 0.00%, Apricot, juice-Uncooked; Frozen; Cook Meth N/S 8001480, 210, 5, 0.00%, Eggplant-Cooked; Fresh or N/S; Cook Meth N/S11000080, 210, 1, 0.00%, Apple, peeled fruit-Cooked; Fresh or N/S; Cook MethN/S 1033000, 221, 16, 0.00%, Potato, tuber, w/o peel-Cooked; Frozen; Baked27002220, 220, 27, 0.00%, Milk, fat-Cooked; Frozen; Cook Meth N/S 1010781, 240, 18, 0.00%, Carrot-babyfood-Cooked; Canned; Cook Meth N/S95001780, 130, 15, 0.00%, Grape, raisin-Uncooked; Dried; Cook Meth N/S 8003761, 240, 29, 0.00%, Tomato, paste-babyfood-Cooked; Canned; Cook MethN/S 1013880, 212, 23, 0.00%, Turnip, roots-Cooked; Fresh or N/S; Boiled 1013140, 213, 19, 0.00%, Radish, roots-Cooked; Fresh or N/S; Fried

360

15001220, 230, 23, 0.00%, Corn, field, bran-Cooked; Dried; Cook Meth N/S19012490, 232, 27, 0.00%, Parsley, dried leaves-Cooked; Dried; Boiled13010580, 130, 8, 0.00%, Boysenberry-Uncooked; Dried; Cook Meth N/S15004020, 221, 24, 0.00%, Wheat, flour-Cooked; Frozen; Baked10001060, 211, 5, 0.00%, Citrus citron-Cooked; Fresh or N/S; Baked 8003740, 240, 18, 0.00%, Tomatillo-Cooked; Canned; Cook Meth N/S19012490, 212, 21, 0.00%, Parsley, dried leaves-Cooked; Fresh or N/S; Boiled95002350, 213, 1, 0.00%, Olive-Cooked; Fresh or N/S; Fried 1031390, 213, 4, 0.00%, Dasheen, corm-Cooked; Fresh or N/S; Fried 8003750, 210, 11, 0.00%, Tomato-Cooked; Fresh or N/S; Cook Meth N/S21000470, 253, 16, 0.00%, Beef, fat-Cooked; Cured etc; Fried 8002720, 250, 19, 0.00%, Pepper, nonbell-Cooked; Cured etc; Cook Meth N/S11000110, 221, 1, 0.00%, Apple, sauce-Cooked; Frozen; Baked14002690, 211, 7, 0.00%, Pecan-Cooked; Fresh or N/S; Baked25002920, 250, 19, 0.00%, Pork, meat byproducts-Cooked; Cured etc; Cook MethN/S15004011, 240, 15, 0.00%, Wheat, grain-babyfood-Cooked; Canned; Cook Meth N/S15001230, 240, 20, 0.00%, Corn, field, starch-Cooked; Canned; Cook Meth N/S10001800, 110, 5, 0.00%, Grapefruit-Uncooked; Fresh or N/S; Cook Meth N/S95003600, 213, 1, 0.00%, Strawberry, juice-Cooked; Fresh or N/S; Fried10002010, 240, 19, 0.00%, Lemon, peel-Cooked; Canned; Cook Meth N/S95003600, 120, 4, 0.00%, Strawberry, juice-Uncooked; Frozen; Cook Meth N/S21000470, 232, 17, 0.00%, Beef, fat-Cooked; Dried; Boiled15001230, 221, 16, 0.00%, Corn, field, starch-Cooked; Frozen; Baked15001270, 242, 6, 0.00%, Corn, sweet-Cooked; Canned; Boiled15001270, 212, 6, 0.00%, Corn, sweet-Cooked; Fresh or N/S; Boiled15004010, 213, 9, 0.00%, Wheat, grain-Cooked; Fresh or N/S; Fried 6030350, 232, 10, 0.00%, Bean, great northern, seed-Cooked; Dried; Boiled 6030400, 232, 10, 0.00%, Bean, navy, seed-Cooked; Dried; Boiled 6003480, 210, 8, 0.00%, Soybean, flour-Cooked; Fresh or N/S; Cook Meth N/S 6003481, 110, 17, 0.00%, Soybean, flour-babyfood-Uncooked; Fresh or N/S;Cook Meth N/S 1010501, 240, 2, 0.00%, Beet, garden, roots-babyfood-Cooked; Canned; CookMeth N/S10003700, 130, 8, 0.00%, Tangerine, juice-Uncooked; Dried; Cook Meth N/S 6010430, 221, 1, 0.00%, Bean, snap, succulent-Cooked; Frozen; Baked 1010500, 212, 6, 0.00%, Beet, garden, roots-Cooked; Fresh or N/S; Boiled 8001480, 215, 2, 0.00%, Eggplant-Cooked; Fresh or N/S; Boiled/baked 1032980, 214, 1, 0.00%, Potato, flour-Cooked; Fresh or N/S; Fried/baked 2000510, 212, 1, 0.00%, Beet, garden, tops-Cooked; Fresh or N/S; Boiled15001200, 232, 2, 0.00%, Corn, field, flour-Cooked; Dried; Boiled12002850, 240, 2, 0.00%, Plum-Cooked; Canned; Cook Meth N/S10002070, 130, 7, 0.00%, Lime, juice-Uncooked; Dried; Cook Meth N/S95002640, 211, 7, 0.00%, Peanut, butter-Cooked; Fresh or N/S; Baked 9023560, 213, 7, 0.00%, Squash, summer-Cooked; Fresh or N/S; Fried15003240, 212, 1, 0.00%, Rice, brown-Cooked; Fresh or N/S; Boiled12000910, 130, 7, 0.00%, Cherry, juice-Uncooked; Dried; Cook Meth N/S15001200, 212, 5, 0.00%, Corn, field, flour-Cooked; Fresh or N/S; Boiled15004010, 210, 7, 0.00%, Wheat, grain-Cooked; Fresh or N/S; Cook Meth N/S 8001480, 213, 1, 0.00%, Eggplant-Cooked; Fresh or N/S; Fried15001230, 230, 6, 0.00%, Corn, field, starch-Cooked; Dried; Cook Meth N/S25002930, 251, 2, 0.00%, Pork, fat-Cooked; Cured etc; Baked 6003490, 230, 1, 0.00%, Soybean, soy milk-Cooked; Dried; Cook Meth N/S15003240, 215, 2, 0.00%, Rice, brown-Cooked; Fresh or N/S; Boiled/baked 6030360, 232, 3, 0.00%, Bean, kidney, seed-Cooked; Dried; Boiled 8002700, 242, 2, 0.00%, Pepper, bell-Cooked; Canned; Boiled 8001480, 212, 2, 0.00%, Eggplant-Cooked; Fresh or N/S; Boiled 1033000, 242, 2, 0.00%, Potato, tuber, w/o peel-Cooked; Canned; Boiled 6030350, 210, 4, 0.00%, Bean, great northern, seed-Cooked; Fresh or N/S;Cook Meth N/S 6030400, 210, 4, 0.00%, Bean, navy, seed-Cooked; Fresh or N/S; Cook MethN/S 4012480, 211, 3, 0.00%, Parsley, leaves-Cooked; Fresh or N/S; Baked21000450, 230, 4, 0.00%, Beef, meat, dried-Cooked; Dried; Cook Meth N/S 6003470, 232, 1, 0.00%, Soybean, seed-Cooked; Dried; Boiled

361

1010500, 242, 3, 0.00%, Beet, garden, roots-Cooked; Canned; Boiled21000470, 214, 5, 0.00%, Beef, fat-Cooked; Fresh or N/S; Fried/baked15001230, 130, 2, 0.00%, Corn, field, starch-Uncooked; Dried; Cook Meth N/S 1010780, 212, 4, 0.00%, Carrot-Cooked; Fresh or N/S; Boiled 6003481, 130, 4, 0.00%, Soybean, flour-babyfood-Uncooked; Dried; Cook MethN/S 8003771, 240, 3, 0.00%, Tomato, puree-babyfood-Cooked; Canned; Cook MethN/S 8003790, 242, 5, 0.00%, Tomato, juice-Cooked; Canned; Boiled 1033001, 240, 1, 0.00%, Potato, tuber, w/o peel-babyfood-Cooked; Canned;Cook Meth N/S95002790, 210, 2, 0.00%, Pineapple-Cooked; Fresh or N/S; Cook Meth N/S19012490, 242, 3, 0.00%, Parsley, dried leaves-Cooked; Canned; Boiled15001241, 110, 3, 0.00%, Corn, field, syrup-babyfood-Uncooked; Fresh or N/S;Cook Meth N/S26003391, 240, 1, 0.00%, Sheep, meat-babyfood-Cooked; Canned; Cook Meth N/S15003230, 232, 3, 0.00%, Rice, white-Cooked; Dried; Boiled 5010830, 110, 4, 0.00%, Cauliflower-Uncooked; Fresh or N/S; Cook Meth N/S15003241, 240, 3, 0.00%, Rice, brown-babyfood-Cooked; Canned; Cook Meth N/S15001260, 210, 5, 0.00%, Corn, pop-Cooked; Fresh or N/S; Cook Meth N/S 5010610, 222, 3, 0.00%, Broccoli-Cooked; Frozen; Boiled13020570, 130, 1, 0.00%, Blueberry-Uncooked; Dried; Cook Meth N/S 8002710, 213, 1, 0.00%, Pepper, bell, dried-Cooked; Fresh or N/S; Fried11000110, 211, 1, 0.00%, Apple, sauce-Cooked; Fresh or N/S; Baked 6032560, 212, 2, 0.00%, Pea, dry-Cooked; Fresh or N/S; Boiled11000101, 230, 1, 0.00%, Apple, juice-babyfood-Cooked; Dried; Cook Meth N/S15004010, 233, 3, 0.00%, Wheat, grain-Cooked; Dried; Fried 1033660, 210, 2, 0.00%, Sweet potato-Cooked; Fresh or N/S; Cook Meth N/S 5010610, 212, 3, 0.00%, Broccoli-Cooked; Fresh or N/S; Boiled 1032980, 212, 2, 0.00%, Potato, flour-Cooked; Fresh or N/S; Boiled 1032981, 240, 2, 0.00%, Potato, flour-babyfood-Cooked; Canned; Cook MethN/S25002900, 251, 2, 0.00%, Pork, meat-Cooked; Cured etc; Baked15001241, 211, 3, 0.00%, Corn, field, syrup-babyfood-Cooked; Fresh or N/S;Baked13013210, 130, 1, 0.00%, Raspberry, juice-Uncooked; Dried; Cook Meth N/S12002860, 211, 2, 0.00%, Plum, prune, fresh-Cooked; Fresh or N/S; Baked 6003470, 240, 3, 0.00%, Soybean, seed-Cooked; Canned; Cook Meth N/S95001780, 210, 1, 0.00%, Grape, raisin-Cooked; Fresh or N/S; Cook Meth N/S25002900, 242, 2, 0.00%, Pork, meat-Cooked; Canned; Boiled27002221, 240, 3, 0.00%, Milk, fat - baby food/infant formula-Cooked;Canned; Cook Meth N/S 8003790, 211, 2, 0.00%, Tomato, juice-Cooked; Fresh or N/S; Baked15001230, 110, 2, 0.00%, Corn, field, starch-Uncooked; Fresh or N/S; CookMeth N/S27002220, 240, 1, 0.00%, Milk, fat-Cooked; Canned; Cook Meth N/S 8003770, 215, 2, 0.00%, Tomato, puree-Cooked; Fresh or N/S; Boiled/baked14000030, 230, 1, 0.00%, Almond-Cooked; Dried; Cook Meth N/S25002920, 213, 1, 0.00%, Pork, meat byproducts-Cooked; Fresh or N/S; Fried 1010780, 242, 2, 0.00%, Carrot-Cooked; Canned; Boiled15001230, 211, 2, 0.00%, Corn, field, starch-Cooked; Fresh or N/S; Baked95001300, 240, 1, 0.00%, Cranberry-Cooked; Canned; Cook Meth N/S95001320, 120, 2, 0.00%, Cranberry, juice-Uncooked; Frozen; Cook Meth N/S 5023890, 222, 1, 0.00%, Turnip, greens-Cooked; Frozen; Boiled19012490, 240, 2, 0.00%, Parsley, dried leaves-Cooked; Canned; Cook Meth N/S 6030980, 232, 1, 0.00%, Chickpea, seed-Cooked; Dried; Boiled10002000, 213, 1, 0.00%, Lemon, juice-Cooked; Fresh or N/S; Fried 4012480, 213, 1, 0.00%, Parsley, leaves-Cooked; Fresh or N/S; Fried12002880, 230, 1, 0.00%, Plum, prune, juice-Cooked; Dried; Cook Meth N/S10002070, 210, 1, 0.00%, Lime, juice-Cooked; Fresh or N/S; Cook Meth N/S12002860, 232, 1, 0.00%, Plum, prune, fresh-Cooked; Dried; Boiled 4013550, 222, 1, 0.00%, Spinach-Cooked; Frozen; Boiled 4012040, 110, 1, 0.00%, Lettuce, head-Uncooked; Fresh or N/S; Cook Meth N/S 1030820, 240, 1, 0.00%, Cassava-Cooked; Canned; Cook Meth N/S15004010, 215, 1, 0.00%, Wheat, grain-Cooked; Fresh or N/S; Boiled/baked

362

6032560, 242, 1, 0.00%, Pea, dry-Cooked; Canned; Boiled15003250, 110, 1, 0.00%, Rice, flour-Uncooked; Fresh or N/S; Cook Meth N/S 1033000, 240, 1, 0.00%, Potato, tuber, w/o peel-Cooked; Canned; Cook MethN/S95002630, 231, 1, 0.00%, Peanut-Cooked; Dried; Baked15004021, 230, 1, 0.00%, Wheat, flour-babyfood-Cooked; Dried; Cook Meth N/S27002220, 222, 1, 0.00%, Milk, fat-Cooked; Frozen; Boiled 1010780, 110, 1, 0.00%, Carrot-Uncooked; Fresh or N/S; Cook Meth N/S 6003480, 230, 1, 0.00%, Soybean, flour-Cooked; Dried; Cook Meth N/S15001240, 213, 1, 0.00%, Corn, field, syrup-Cooked; Fresh or N/S; Fried 8002730, 230, 1, 0.00%, Pepper, nonbell, dried-Cooked; Dried; Cook Meth N/S 6003470, 210, 1, 0.00%, Soybean, seed-Cooked; Fresh or N/S; Cook Meth N/S95001780, 230, 1, 0.00%, Grape, raisin-Cooked; Dried; Cook Meth N/S15004021, 231, 1, 0.00%, Wheat, flour-babyfood-Cooked; Dried; Baked21000440, 253, 1, 0.00%, Beef, meat-Cooked; Cured etc; Fried26003390, 213, 1, 0.00%, Sheep, meat-Cooked; Fresh or N/S; Fried 9021350, 210, 1, 0.00%, Cucumber-Cooked; Fresh or N/S; Cook Meth N/S 8002710, 110, 1, 0.00%, Pepper, bell, dried-Uncooked; Fresh or N/S; CookMeth N/S15001230, 232, 1, 0.00%, Corn, field, starch-Cooked; Dried; Boiled 1010780, 222, 1, 0.00%, Carrot-Cooked; Frozen; Boiled26003410, 213, 1, 0.00%, Sheep, fat-Cooked; Fresh or N/S; Fried27002220, 130, 1, 0.00%, Milk, fat-Uncooked; Dried; Cook Meth N/S

363

Non-hispanic blacksLow percentile for CEC records: 95 Exposure (mg/day) = 0.000446High percentile for CEC records: 100 Exposure (mg/day) = 0.055984Number of actual records in this interval: 7406

Critical foods/foodforms for this population (as derived from these records): N=number of appearances in all records (including duplicates) %=percent of total exposure for all records (including duplicates)

Food, FF, N , Percent, Food Name --------, ---, -----, -------, ------------- 5022290, 212, 589, 17.21%, Mustard greens-Cooked; Fresh or N/S; Boiled10002000, 110, 1571, 8.33%, Lemon, juice-Uncooked; Fresh or N/S; Cook Meth N/S 5022290, 242, 114, 7.28%, Mustard greens-Cooked; Canned; Boiled12002880, 110, 57, 5.28%, Plum, prune, juice-Uncooked; Fresh or N/S; CookMeth N/S 8002340, 210, 342, 4.50%, Okra-Cooked; Fresh or N/S; Cook Meth N/S12000910, 210, 779, 3.43%, Cherry, juice-Cooked; Fresh or N/S; Cook Meth N/S95002810, 110, 503, 3.25%, Pineapple, juice-Uncooked; Fresh or N/S; Cook MethN/S 8002340, 220, 191, 3.02%, Okra-Cooked; Frozen; Cook Meth N/S12002881, 240, 152, 2.57%, Plum, prune, juice-babyfood-Cooked; Canned; CookMeth N/S 5022290, 222, 57, 2.40%, Mustard greens-Cooked; Frozen; Boiled12000910, 110, 95, 2.32%, Cherry, juice-Uncooked; Fresh or N/S; Cook Meth N/S11000070, 110, 207, 2.12%, Apple, fruit with peel-Uncooked; Fresh or N/S; CookMeth N/S12002620, 110, 57, 2.04%, Peach, juice-Uncooked; Fresh or N/S; Cook Meth N/S95002810, 240, 1489, 2.01%, Pineapple, juice-Cooked; Canned; Cook Meth N/S10001810, 240, 951, 1.67%, Grapefruit, juice-Cooked; Canned; Cook Meth N/S12000911, 240, 228, 1.42%, Cherry, juice-babyfood-Cooked; Canned; Cook MethN/S10003700, 240, 1234, 1.15%, Tangerine, juice-Cooked; Canned; Cook Meth N/S10002000, 240, 1214, 1.10%, Lemon, juice-Cooked; Canned; Cook Meth N/S95001750, 110, 80, 1.03%, Grape-Uncooked; Fresh or N/S; Cook Meth N/S 8002720, 110, 133, 1.01%, Pepper, nonbell-Uncooked; Fresh or N/S; Cook MethN/S10002070, 240, 1073, 0.98%, Lime, juice-Cooked; Canned; Cook Meth N/S13010580, 240, 1069, 0.98%, Boysenberry-Cooked; Canned; Cook Meth N/S11000090, 211, 190, 0.89%, Apple, dried-Cooked; Fresh or N/S; Baked10001810, 110, 236, 0.88%, Grapefruit, juice-Uncooked; Fresh or N/S; Cook MethN/S10002000, 210, 763, 0.77%, Lemon, juice-Cooked; Fresh or N/S; Cook Meth N/S11000100, 110, 687, 0.77%, Apple, juice-Uncooked; Fresh or N/S; Cook Meth N/S 5020700, 210, 58, 0.77%, Cabbage, Chinese, bok choy-Cooked; Fresh or N/S;Cook Meth N/S12000910, 240, 721, 0.62%, Cherry, juice-Cooked; Canned; Cook Meth N/S25002930, 210, 1519, 0.61%, Pork, fat-Cooked; Fresh or N/S; Cook Meth N/S12002600, 240, 99, 0.58%, Peach-Cooked; Canned; Cook Meth N/S12002601, 240, 36, 0.54%, Peach-babyfood-Cooked; Canned; Cook Meth N/S95001760, 240, 766, 0.53%, Grape, juice-Cooked; Canned; Cook Meth N/S13020570, 211, 63, 0.53%, Blueberry-Cooked; Fresh or N/S; Baked12002621, 240, 38, 0.47%, Peach, juice-babyfood-Cooked; Canned; Cook Meth N/S95001760, 110, 389, 0.43%, Grape, juice-Uncooked; Fresh or N/S; Cook Meth N/S25002930, 213, 650, 0.43%, Pork, fat-Cooked; Fresh or N/S; Fried11000110, 212, 232, 0.41%, Apple, sauce-Cooked; Fresh or N/S; Boiled11000091, 230, 76, 0.38%, Apple, dried-babyfood-Cooked; Dried; Cook Meth N/S10002000, 130, 160, 0.36%, Lemon, juice-Uncooked; Dried; Cook Meth N/S27002220, 110, 2185, 0.33%, Milk, fat-Uncooked; Fresh or N/S; Cook Meth N/S25002930, 250, 647, 0.31%, Pork, fat-Cooked; Cured etc; Cook Meth N/S10002070, 110, 95, 0.31%, Lime, juice-Uncooked; Fresh or N/S; Cook Meth N/S15003251, 230, 344, 0.30%, Rice, flour-babyfood-Cooked; Dried; Cook Meth N/S 8002340, 213, 57, 0.28%, Okra-Cooked; Fresh or N/S; Fried12002620, 240, 19, 0.28%, Peach, juice-Cooked; Canned; Cook Meth N/S

364

15001240, 240, 1605, 0.28%, Corn, field, syrup-Cooked; Canned; Cook Meth N/S15003250, 230, 460, 0.27%, Rice, flour-Cooked; Dried; Cook Meth N/S 8002730, 210, 418, 0.26%, Pepper, nonbell, dried-Cooked; Fresh or N/S; CookMeth N/S10002410, 110, 760, 0.26%, Orange, juice-Uncooked; Fresh or N/S; Cook Meth N/S 8002720, 213, 58, 0.25%, Pepper, nonbell-Cooked; Fresh or N/S; Fried11000100, 240, 498, 0.25%, Apple, juice-Cooked; Canned; Cook Meth N/S11000101, 240, 322, 0.25%, Apple, juice-babyfood-Cooked; Canned; Cook Meth N/S12002600, 110, 32, 0.24%, Peach-Uncooked; Fresh or N/S; Cook Meth N/S 8002720, 210, 177, 0.22%, Pepper, nonbell-Cooked; Fresh or N/S; Cook Meth N/S95002811, 240, 88, 0.21%, Pineapple, juice-babyfood-Cooked; Canned; Cook MethN/S10003690, 110, 41, 0.20%, Tangerine-Uncooked; Fresh or N/S; Cook Meth N/S25002930, 253, 416, 0.20%, Pork, fat-Cooked; Cured etc; Fried12002610, 130, 38, 0.19%, Peach, dried-Uncooked; Dried; Cook Meth N/S15004020, 211, 1675, 0.19%, Wheat, flour-Cooked; Fresh or N/S; Baked11002660, 110, 13, 0.18%, Pear-Uncooked; Fresh or N/S; Cook Meth N/S 8002700, 210, 56, 0.18%, Pepper, bell-Cooked; Fresh or N/S; Cook Meth N/S11002661, 240, 15, 0.17%, Pear-babyfood-Cooked; Canned; Cook Meth N/S10003700, 110, 57, 0.17%, Tangerine, juice-Uncooked; Fresh or N/S; Cook MethN/S13020571, 240, 7, 0.16%, Blueberry-babyfood-Cooked; Canned; Cook Meth N/S21000470, 210, 1010, 0.15%, Beef, fat-Cooked; Fresh or N/S; Cook Meth N/S11000111, 240, 114, 0.15%, Apple, sauce-babyfood-Cooked; Canned; Cook Meth N/S13013200, 240, 29, 0.14%, Raspberry-Cooked; Canned; Cook Meth N/S15003251, 240, 156, 0.14%, Rice, flour-babyfood-Cooked; Canned; Cook Meth N/S 4020860, 110, 19, 0.13%, Celery, juice-Uncooked; Fresh or N/S; Cook Meth N/S95003590, 110, 13, 0.13%, Strawberry-Uncooked; Fresh or N/S; Cook Meth N/S15001240, 110, 1073, 0.13%, Corn, field, syrup-Uncooked; Fresh or N/S; CookMeth N/S11002660, 240, 24, 0.12%, Pear-Cooked; Canned; Cook Meth N/S13010550, 240, 70, 0.11%, Blackberry-Cooked; Canned; Cook Meth N/S11000081, 240, 19, 0.11%, Apple, peeled fruit-babyfood-Cooked; Canned; CookMeth N/S21000440, 210, 827, 0.11%, Beef, meat-Cooked; Fresh or N/S; Cook Meth N/S12000130, 130, 28, 0.10%, Apricot, dried-Uncooked; Dried; Cook Meth N/S 8002700, 110, 29, 0.09%, Pepper, bell-Uncooked; Fresh or N/S; Cook Meth N/S11000090, 230, 197, 0.09%, Apple, dried-Cooked; Dried; Cook Meth N/S10002000, 211, 104, 0.09%, Lemon, juice-Cooked; Fresh or N/S; Baked95003600, 240, 30, 0.09%, Strawberry, juice-Cooked; Canned; Cook Meth N/S13020570, 240, 38, 0.09%, Blueberry-Cooked; Canned; Cook Meth N/S10002070, 120, 134, 0.09%, Lime, juice-Uncooked; Frozen; Cook Meth N/S 8002730, 212, 148, 0.09%, Pepper, nonbell, dried-Cooked; Fresh or N/S; Boiled10002400, 110, 26, 0.09%, Orange-Uncooked; Fresh or N/S; Cook Meth N/S15001200, 230, 571, 0.09%, Corn, field, flour-Cooked; Dried; Cook Meth N/S10002001, 240, 76, 0.08%, Lemon, juice-babyfood-Cooked; Canned; Cook Meth N/S25002900, 250, 551, 0.08%, Pork, meat-Cooked; Cured etc; Cook Meth N/S95002350, 240, 6, 0.08%, Olive-Cooked; Canned; Cook Meth N/S25002930, 211, 349, 0.08%, Pork, fat-Cooked; Fresh or N/S; Baked 2001400, 212, 19, 0.07%, Dasheen, leaves-Cooked; Fresh or N/S; Boiled15004020, 232, 344, 0.07%, Wheat, flour-Cooked; Dried; Boiled25002930, 240, 26, 0.07%, Pork, fat-Cooked; Canned; Cook Meth N/S95001761, 240, 61, 0.07%, Grape, juice-babyfood-Cooked; Canned; Cook Meth N/S11000080, 211, 10, 0.07%, Apple, peeled fruit-Cooked; Fresh or N/S; Baked 8002720, 150, 20, 0.07%, Pepper, nonbell-Uncooked; Cured etc; Cook Meth N/S 8002340, 212, 61, 0.06%, Okra-Cooked; Fresh or N/S; Boiled 6010430, 242, 14, 0.06%, Bean, snap, succulent-Cooked; Canned; Boiled10001070, 110, 19, 0.06%, Citrus hybrids-Uncooked; Fresh or N/S; Cook MethN/S13010580, 120, 74, 0.06%, Boysenberry-Uncooked; Frozen; Cook Meth N/S11002681, 240, 5, 0.06%, Pear, juice-babyfood-Cooked; Canned; Cook Meth N/S 8002700, 213, 13, 0.06%, Pepper, bell-Cooked; Fresh or N/S; Fried 8003770, 210, 236, 0.06%, Tomato, puree-Cooked; Fresh or N/S; Cook Meth N/S21000440, 213, 490, 0.06%, Beef, meat-Cooked; Fresh or N/S; Fried15001210, 233, 354, 0.06%, Corn, field, meal-Cooked; Dried; Fried

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8003770, 240, 278, 0.05%, Tomato, puree-Cooked; Canned; Cook Meth N/S25002900, 210, 374, 0.05%, Pork, meat-Cooked; Fresh or N/S; Cook Meth N/S 8002730, 240, 150, 0.05%, Pepper, nonbell, dried-Cooked; Canned; Cook MethN/S25002900, 213, 324, 0.05%, Pork, meat-Cooked; Fresh or N/S; Fried13010580, 110, 38, 0.05%, Boysenberry-Uncooked; Fresh or N/S; Cook Meth N/S27002220, 232, 199, 0.05%, Milk, fat-Cooked; Dried; Boiled11000090, 130, 38, 0.05%, Apple, dried-Uncooked; Dried; Cook Meth N/S21000470, 213, 439, 0.05%, Beef, fat-Cooked; Fresh or N/S; Fried11002670, 130, 38, 0.05%, Pear, dried-Uncooked; Dried; Cook Meth N/S95001750, 210, 31, 0.05%, Grape-Cooked; Fresh or N/S; Cook Meth N/S 4012480, 210, 201, 0.04%, Parsley, leaves-Cooked; Fresh or N/S; Cook Meth N/S12000141, 240, 10, 0.04%, Apricot, juice-babyfood-Cooked; Canned; Cook MethN/S12000900, 211, 5, 0.04%, Cherry-Cooked; Fresh or N/S; Baked 6010430, 212, 8, 0.04%, Bean, snap, succulent-Cooked; Fresh or N/S; Boiled11002660, 210, 26, 0.04%, Pear-Cooked; Fresh or N/S; Cook Meth N/S10002410, 240, 262, 0.04%, Orange, juice-Cooked; Canned; Cook Meth N/S95002350, 211, 7, 0.04%, Olive-Cooked; Fresh or N/S; Baked13020570, 110, 12, 0.04%, Blueberry-Uncooked; Fresh or N/S; Cook Meth N/S25002931, 240, 99, 0.04%, Pork, fat-babyfood-Cooked; Canned; Cook Meth N/S21000440, 211, 194, 0.04%, Beef, meat-Cooked; Fresh or N/S; Baked13020570, 214, 1, 0.03%, Blueberry-Cooked; Fresh or N/S; Fried/baked15001210, 230, 225, 0.03%, Corn, field, meal-Cooked; Dried; Cook Meth N/S10002410, 120, 137, 0.03%, Orange, juice-Uncooked; Frozen; Cook Meth N/S12000900, 240, 24, 0.03%, Cherry-Cooked; Canned; Cook Meth N/S15001240, 130, 233, 0.03%, Corn, field, syrup-Uncooked; Dried; Cook Meth N/S13013210, 240, 54, 0.03%, Raspberry, juice-Cooked; Canned; Cook Meth N/S11000070, 213, 2, 0.03%, Apple, fruit with peel-Cooked; Fresh or N/S; Fried10003700, 120, 73, 0.03%, Tangerine, juice-Uncooked; Frozen; Cook Meth N/S15004020, 210, 234, 0.03%, Wheat, flour-Cooked; Fresh or N/S; Cook Meth N/S15001241, 240, 95, 0.03%, Corn, field, syrup-babyfood-Cooked; Canned; CookMeth N/S95001750, 240, 14, 0.03%, Grape-Cooked; Canned; Cook Meth N/S14000810, 211, 20, 0.03%, Cashew-Cooked; Fresh or N/S; Baked95002790, 240, 106, 0.03%, Pineapple-Cooked; Canned; Cook Meth N/S10002000, 120, 72, 0.03%, Lemon, juice-Uncooked; Frozen; Cook Meth N/S11000070, 211, 5, 0.03%, Apple, fruit with peel-Cooked; Fresh or N/S; Baked95000230, 110, 304, 0.03%, Banana-Uncooked; Fresh or N/S; Cook Meth N/S 8003760, 210, 202, 0.03%, Tomato, paste-Cooked; Fresh or N/S; Cook Meth N/S21000441, 240, 86, 0.03%, Beef, meat-babyfood-Cooked; Canned; Cook Meth N/S12002300, 110, 5, 0.02%, Nectarine-Uncooked; Fresh or N/S; Cook Meth N/S11002680, 240, 19, 0.02%, Pear, juice-Cooked; Canned; Cook Meth N/S25002930, 212, 104, 0.02%, Pork, fat-Cooked; Fresh or N/S; Boiled15001210, 232, 136, 0.02%, Corn, field, meal-Cooked; Dried; Boiled12002600, 120, 3, 0.02%, Peach-Uncooked; Frozen; Cook Meth N/S15004020, 213, 231, 0.02%, Wheat, flour-Cooked; Fresh or N/S; Fried95002800, 130, 38, 0.02%, Pineapple, dried-Uncooked; Dried; Cook Meth N/S12002600, 211, 5, 0.02%, Peach-Cooked; Fresh or N/S; Baked13013200, 110, 11, 0.02%, Raspberry-Uncooked; Fresh or N/S; Cook Meth N/S15004020, 231, 225, 0.02%, Wheat, flour-Cooked; Dried; Baked 9011870, 110, 6, 0.02%, Honeydew melon-Uncooked; Fresh or N/S; Cook MethN/S12000121, 240, 22, 0.02%, Apricot-babyfood-Cooked; Canned; Cook Meth N/S95002350, 210, 2, 0.02%, Olive-Cooked; Fresh or N/S; Cook Meth N/S12000910, 120, 71, 0.02%, Cherry, juice-Uncooked; Frozen; Cook Meth N/S13013210, 110, 3, 0.02%, Raspberry, juice-Uncooked; Fresh or N/S; Cook MethN/S 8002730, 213, 98, 0.02%, Pepper, nonbell, dried-Cooked; Fresh or N/S; Fried25002901, 240, 79, 0.02%, Pork, meat-babyfood-Cooked; Canned; Cook Meth N/S 9010750, 110, 13, 0.02%, Cantaloupe-Uncooked; Fresh or N/S; Cook Meth N/S20003651, 900, 163, 0.02%, Sunflower, oil-babyfood-Refined; FF N/A; Cook MethN/S15003240, 210, 20, 0.02%, Rice, brown-Cooked; Fresh or N/S; Cook Meth N/S 8002720, 240, 48, 0.02%, Pepper, nonbell-Cooked; Canned; Cook Meth N/S

366

8002340, 242, 19, 0.02%, Okra-Cooked; Canned; Boiled21000460, 210, 77, 0.02%, Beef, meat byproducts-Cooked; Fresh or N/S; CookMeth N/S95003590, 240, 5, 0.02%, Strawberry-Cooked; Canned; Cook Meth N/S21000470, 211, 154, 0.02%, Beef, fat-Cooked; Fresh or N/S; Baked10001990, 110, 41, 0.02%, Lemon-Uncooked; Fresh or N/S; Cook Meth N/S 6010431, 240, 4, 0.02%, Bean, snap, succulent-babyfood-Cooked; Canned; CookMeth N/S 8002720, 212, 88, 0.01%, Pepper, nonbell-Cooked; Fresh or N/S; Boiled21000440, 212, 113, 0.01%, Beef, meat-Cooked; Fresh or N/S; Boiled25002900, 211, 50, 0.01%, Pork, meat-Cooked; Fresh or N/S; Baked95002360, 900, 72, 0.01%, Olive, oil-Refined; FF N/A; Cook Meth N/S27002220, 120, 166, 0.01%, Milk, fat-Uncooked; Frozen; Cook Meth N/S15004010, 211, 119, 0.01%, Wheat, grain-Cooked; Fresh or N/S; Baked 4013550, 242, 3, 0.01%, Spinach-Cooked; Canned; Boiled 1030821, 240, 68, 0.01%, Cassava-babyfood-Cooked; Canned; Cook Meth N/S15001260, 230, 74, 0.01%, Corn, pop-Cooked; Dried; Cook Meth N/S15004020, 230, 108, 0.01%, Wheat, flour-Cooked; Dried; Cook Meth N/S 1033661, 240, 21, 0.01%, Sweet potato-babyfood-Cooked; Canned; Cook Meth N/S95002640, 210, 138, 0.01%, Peanut, butter-Cooked; Fresh or N/S; Cook Meth N/S 9021350, 110, 14, 0.01%, Cucumber-Uncooked; Fresh or N/S; Cook Meth N/S 1033000, 212, 14, 0.01%, Potato, tuber, w/o peel-Cooked; Fresh or N/S;Boiled12002850, 110, 9, 0.01%, Plum-Uncooked; Fresh or N/S; Cook Meth N/S 8002700, 211, 11, 0.01%, Pepper, bell-Cooked; Fresh or N/S; Baked15001231, 240, 99, 0.01%, Corn, field, starch-babyfood-Cooked; Canned; CookMeth N/S95003600, 210, 15, 0.01%, Strawberry, juice-Cooked; Fresh or N/S; Cook MethN/S12000901, 240, 6, 0.01%, Cherry-babyfood-Cooked; Canned; Cook Meth N/S27002220, 210, 121, 0.01%, Milk, fat-Cooked; Fresh or N/S; Cook Meth N/S25002900, 240, 22, 0.01%, Pork, meat-Cooked; Canned; Cook Meth N/S95002810, 120, 69, 0.01%, Pineapple, juice-Uncooked; Frozen; Cook Meth N/S10001810, 120, 67, 0.01%, Grapefruit, juice-Uncooked; Frozen; Cook Meth N/S 8002730, 232, 44, 0.01%, Pepper, nonbell, dried-Cooked; Dried; Boiled13013201, 240, 6, 0.01%, Raspberry-babyfood-Cooked; Canned; Cook Meth N/S 8002700, 221, 3, 0.01%, Pepper, bell-Cooked; Frozen; Baked 1033660, 212, 17, 0.01%, Sweet potato-Cooked; Fresh or N/S; Boiled27002220, 211, 121, 0.01%, Milk, fat-Cooked; Fresh or N/S; Baked27002220, 215, 83, 0.01%, Milk, fat-Cooked; Fresh or N/S; Boiled/baked15001210, 211, 82, 0.01%, Corn, field, meal-Cooked; Fresh or N/S; Baked21000470, 212, 53, 0.01%, Beef, fat-Cooked; Fresh or N/S; Boiled95001320, 240, 79, 0.01%, Cranberry, juice-Cooked; Canned; Cook Meth N/S 6003490, 210, 15, 0.01%, Soybean, soy milk-Cooked; Fresh or N/S; Cook MethN/S11000100, 120, 3, 0.01%, Apple, juice-Uncooked; Frozen; Cook Meth N/S 8003770, 212, 50, 0.01%, Tomato, puree-Cooked; Fresh or N/S; Boiled13020570, 213, 1, 0.01%, Blueberry-Cooked; Fresh or N/S; Fried 8003790, 212, 19, 0.01%, Tomato, juice-Cooked; Fresh or N/S; Boiled 9014000, 110, 19, 0.01%, Watermelon, juice-Uncooked; Fresh or N/S; Cook MethN/S15001201, 230, 19, 0.01%, Corn, field, flour-babyfood-Cooked; Dried; CookMeth N/S11000080, 213, 1, 0.01%, Apple, peeled fruit-Cooked; Fresh or N/S; Fried 9021350, 240, 15, 0.01%, Cucumber-Cooked; Canned; Cook Meth N/S25002900, 253, 26, 0.01%, Pork, meat-Cooked; Cured etc; Fried 8002700, 215, 2, 0.01%, Pepper, bell-Cooked; Fresh or N/S; Boiled/baked 1032990, 212, 13, 0.01%, Potato, tuber, w/peel-Cooked; Fresh or N/S; Boiled21000440, 214, 33, 0.01%, Beef, meat-Cooked; Fresh or N/S; Fried/baked25002930, 242, 26, 0.01%, Pork, fat-Cooked; Canned; Boiled 8002700, 150, 3, 0.01%, Pepper, bell-Uncooked; Cured etc; Cook Meth N/S15001200, 213, 56, 0.01%, Corn, field, flour-Cooked; Fresh or N/S; Fried21000471, 240, 35, 0.01%, Beef,fat-babyfood-Cooked; Canned; Cook Meth N/S 1033660, 210, 24, 0.00%, Sweet potato-Cooked; Fresh or N/S; Cook Meth N/S12000900, 110, 7, 0.00%, Cherry-Uncooked; Fresh or N/S; Cook Meth N/S

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9013990, 110, 16, 0.00%, Watermelon-Uncooked; Fresh or N/S; Cook Meth N/S 5010690, 110, 48, 0.00%, Cabbage-Uncooked; Fresh or N/S; Cook Meth N/S12000130, 211, 1, 0.00%, Apricot, dried-Cooked; Fresh or N/S; Baked25002920, 210, 23, 0.00%, Pork, meat byproducts-Cooked; Fresh or N/S; CookMeth N/S21000470, 240, 42, 0.00%, Beef, fat-Cooked; Canned; Cook Meth N/S15001240, 212, 27, 0.00%, Corn, field, syrup-Cooked; Fresh or N/S; Boiled27002220, 213, 32, 0.00%, Milk, fat-Cooked; Fresh or N/S; Fried 1030820, 240, 19, 0.00%, Cassava-Cooked; Canned; Cook Meth N/S15001240, 120, 47, 0.00%, Corn, field, syrup-Uncooked; Frozen; Cook Meth N/S13013200, 211, 3, 0.00%, Raspberry-Cooked; Fresh or N/S; Baked 6030420, 232, 38, 0.00%, Bean, pinto, seed-Cooked; Dried; Boiled15004020, 215, 44, 0.00%, Wheat, flour-Cooked; Fresh or N/S; Boiled/baked11000080, 240, 3, 0.00%, Apple, peeled fruit-Cooked; Canned; Cook Meth N/S11000070, 150, 1, 0.00%, Apple, fruit with peel-Uncooked; Cured etc; CookMeth N/S15004020, 212, 51, 0.00%, Wheat, flour-Cooked; Fresh or N/S; Boiled95003600, 110, 2, 0.00%, Strawberry, juice-Uncooked; Fresh or N/S; Cook MethN/S13020570, 120, 6, 0.00%, Blueberry-Uncooked; Frozen; Cook Meth N/S25002930, 251, 19, 0.00%, Pork, fat-Cooked; Cured etc; Baked 6030400, 232, 42, 0.00%, Bean, navy, seed-Cooked; Dried; Boiled 6030350, 232, 42, 0.00%, Bean, great northern, seed-Cooked; Dried; Boiled15004020, 240, 44, 0.00%, Wheat, flour-Cooked; Canned; Cook Meth N/S15004040, 230, 21, 0.00%, Wheat, bran-Cooked; Dried; Cook Meth N/S12000140, 240, 26, 0.00%, Apricot, juice-Cooked; Canned; Cook Meth N/S95002630, 211, 22, 0.00%, Peanut-Cooked; Fresh or N/S; Baked 1010790, 110, 7, 0.00%, Carrot, juice-Uncooked; Fresh or N/S; Cook Meth N/S15001230, 110, 20, 0.00%, Corn, field, starch-Uncooked; Fresh or N/S; CookMeth N/S10002000, 232, 9, 0.00%, Lemon, juice-Cooked; Dried; Boiled95001760, 210, 18, 0.00%, Grape, juice-Cooked; Fresh or N/S; Cook Meth N/S 4012480, 110, 19, 0.00%, Parsley, leaves-Uncooked; Fresh or N/S; Cook MethN/S15001230, 232, 17, 0.00%, Corn, field, starch-Cooked; Dried; Boiled27002220, 212, 28, 0.00%, Milk, fat-Cooked; Fresh or N/S; Boiled15001240, 210, 20, 0.00%, Corn, field, syrup-Cooked; Fresh or N/S; Cook MethN/S21000440, 240, 33, 0.00%, Beef, meat-Cooked; Canned; Cook Meth N/S15001210, 212, 22, 0.00%, Corn, field, meal-Cooked; Fresh or N/S; Boiled 8002720, 232, 19, 0.00%, Pepper, nonbell-Cooked; Dried; Boiled25002900, 251, 19, 0.00%, Pork, meat-Cooked; Cured etc; Baked15001241, 230, 21, 0.00%, Corn, field, syrup-babyfood-Cooked; Dried; CookMeth N/S15001230, 230, 18, 0.00%, Corn, field, starch-Cooked; Dried; Cook Meth N/S 6003490, 230, 2, 0.00%, Soybean, soy milk-Cooked; Dried; Cook Meth N/S15004020, 214, 25, 0.00%, Wheat, flour-Cooked; Fresh or N/S; Fried/baked 6010430, 222, 1, 0.00%, Bean, snap, succulent-Cooked; Frozen; Boiled 8002720, 215, 7, 0.00%, Pepper, nonbell-Cooked; Fresh or N/S; Boiled/baked15001240, 230, 19, 0.00%, Corn, field, syrup-Cooked; Dried; Cook Meth N/S27022240, 110, 26, 0.00%, Milk, water-Uncooked; Fresh or N/S; Cook Meth N/S 8003750, 212, 8, 0.00%, Tomato-Cooked; Fresh or N/S; Boiled 6030350, 210, 21, 0.00%, Bean, great northern, seed-Cooked; Fresh or N/S;Cook Meth N/S 6030400, 210, 21, 0.00%, Bean, navy, seed-Cooked; Fresh or N/S; Cook MethN/S 1033000, 211, 3, 0.00%, Potato, tuber, w/o peel-Cooked; Fresh or N/S; Baked 4011500, 110, 2, 0.00%, Endive-Uncooked; Fresh or N/S; Cook Meth N/S12000120, 240, 18, 0.00%, Apricot-Cooked; Canned; Cook Meth N/S21000470, 214, 20, 0.00%, Beef, fat-Cooked; Fresh or N/S; Fried/baked25002930, 230, 3, 0.00%, Pork, fat-Cooked; Dried; Cook Meth N/S21000440, 221, 21, 0.00%, Beef, meat-Cooked; Frozen; Baked 8002730, 211, 20, 0.00%, Pepper, nonbell, dried-Cooked; Fresh or N/S; Baked13013210, 120, 5, 0.00%, Raspberry, juice-Uncooked; Frozen; Cook Meth N/S15004021, 230, 15, 0.00%, Wheat, flour-babyfood-Cooked; Dried; Cook Meth N/S

368

11002680, 110, 3, 0.00%, Pear, juice-Uncooked; Fresh or N/S; Cook Meth N/S13010550, 120, 5, 0.00%, Blackberry-Uncooked; Frozen; Cook Meth N/S15001210, 231, 21, 0.00%, Corn, field, meal-Cooked; Dried; Baked95001320, 110, 6, 0.00%, Cranberry, juice-Uncooked; Fresh or N/S; Cook MethN/S 8003750, 110, 14, 0.00%, Tomato-Uncooked; Fresh or N/S; Cook Meth N/S 8003760, 213, 17, 0.00%, Tomato, paste-Cooked; Fresh or N/S; Fried10002010, 230, 19, 0.00%, Lemon, peel-Cooked; Dried; Cook Meth N/S15001230, 120, 18, 0.00%, Corn, field, starch-Uncooked; Frozen; Cook Meth N/S21000470, 253, 15, 0.00%, Beef, fat-Cooked; Cured etc; Fried13020570, 210, 2, 0.00%, Blueberry-Cooked; Fresh or N/S; Cook Meth N/S11000100, 210, 8, 0.00%, Apple, juice-Cooked; Fresh or N/S; Cook Meth N/S15003250, 232, 1, 0.00%, Rice, flour-Cooked; Dried; Boiled25002920, 213, 17, 0.00%, Pork, meat byproducts-Cooked; Fresh or N/S; Fried 8003770, 211, 16, 0.00%, Tomato, puree-Cooked; Fresh or N/S; Baked25002930, 232, 6, 0.00%, Pork, fat-Cooked; Dried; Boiled 1033660, 211, 13, 0.00%, Sweet potato-Cooked; Fresh or N/S; Baked15004020, 221, 18, 0.00%, Wheat, flour-Cooked; Frozen; Baked12000140, 120, 2, 0.00%, Apricot, juice-Uncooked; Frozen; Cook Meth N/S21000470, 250, 5, 0.00%, Beef, fat-Cooked; Cured etc; Cook Meth N/S 6030420, 213, 14, 0.00%, Bean, pinto, seed-Cooked; Fresh or N/S; Fried 4013551, 240, 1, 0.00%, Spinach-babyfood-Cooked; Canned; Cook Meth N/S 1010781, 240, 7, 0.00%, Carrot-babyfood-Cooked; Canned; Cook Meth N/S15001240, 211, 13, 0.00%, Corn, field, syrup-Cooked; Fresh or N/S; Baked95002640, 240, 12, 0.00%, Peanut, butter-Cooked; Canned; Cook Meth N/S27002220, 230, 5, 0.00%, Milk, fat-Cooked; Dried; Cook Meth N/S 6030360, 212, 15, 0.00%, Bean, kidney, seed-Cooked; Fresh or N/S; Boiled15001231, 130, 4, 0.00%, Corn, field, starch-babyfood-Uncooked; Dried; CookMeth N/S 8002700, 212, 2, 0.00%, Pepper, bell-Cooked; Fresh or N/S; Boiled11000110, 210, 1, 0.00%, Apple, sauce-Cooked; Fresh or N/S; Cook Meth N/S15001270, 222, 1, 0.00%, Corn, sweet-Cooked; Frozen; Boiled 5021170, 212, 4, 0.00%, Collards-Cooked; Fresh or N/S; Boiled95001760, 120, 2, 0.00%, Grape, juice-Uncooked; Frozen; Cook Meth N/S 2001010, 110, 2, 0.00%, Chicory, tops-Uncooked; Fresh or N/S; Cook Meth N/S21000440, 250, 5, 0.00%, Beef, meat-Cooked; Cured etc; Cook Meth N/S 8003750, 215, 2, 0.00%, Tomato-Cooked; Fresh or N/S; Boiled/baked15003250, 211, 2, 0.00%, Rice, flour-Cooked; Fresh or N/S; Baked13010550, 110, 2, 0.00%, Blackberry-Uncooked; Fresh or N/S; Cook Meth N/S15003250, 210, 3, 0.00%, Rice, flour-Cooked; Fresh or N/S; Cook Meth N/S25002930, 222, 3, 0.00%, Pork, fat-Cooked; Frozen; Boiled15001241, 130, 1, 0.00%, Corn, field, syrup-babyfood-Uncooked; Dried; CookMeth N/S 6003481, 240, 4, 0.00%, Soybean, flour-babyfood-Cooked; Canned; Cook MethN/S27002220, 240, 2, 0.00%, Milk, fat-Cooked; Canned; Cook Meth N/S15003250, 120, 4, 0.00%, Rice, flour-Uncooked; Frozen; Cook Meth N/S15001260, 231, 4, 0.00%, Corn, pop-Cooked; Dried; Baked95002790, 110, 2, 0.00%, Pineapple-Uncooked; Fresh or N/S; Cook Meth N/S 6030380, 232, 3, 0.00%, Bean, lima, seed-Cooked; Dried; Boiled 8002710, 213, 1, 0.00%, Pepper, bell, dried-Cooked; Fresh or N/S; Fried21000470, 221, 2, 0.00%, Beef, fat-Cooked; Frozen; Baked15004010, 230, 4, 0.00%, Wheat, grain-Cooked; Dried; Cook Meth N/S 8003760, 212, 4, 0.00%, Tomato, paste-Cooked; Fresh or N/S; Boiled27002220, 221, 2, 0.00%, Milk, fat-Cooked; Frozen; Baked 8003790, 240, 1, 0.00%, Tomato, juice-Cooked; Canned; Cook Meth N/S 1032981, 240, 2, 0.00%, Potato, flour-babyfood-Cooked; Canned; Cook MethN/S25002900, 212, 2, 0.00%, Pork, meat-Cooked; Fresh or N/S; Boiled19011440, 240, 1, 0.00%, Dillweed-Cooked; Canned; Cook Meth N/S 8003750, 213, 2, 0.00%, Tomato-Cooked; Fresh or N/S; Fried 1034060, 210, 1, 0.00%, Yam, true-Cooked; Fresh or N/S; Cook Meth N/S95002630, 112, 2, 0.00%, Peanut-Uncooked; Fresh or N/S; Boiled10001800, 110, 1, 0.00%, Grapefruit-Uncooked; Fresh or N/S; Cook Meth N/S15004021, 240, 3, 0.00%, Wheat, flour-babyfood-Cooked; Canned; Cook Meth N/S

369

5023890, 242, 2, 0.00%, Turnip, greens-Cooked; Canned; Boiled 6003470, 240, 2, 0.00%, Soybean, seed-Cooked; Canned; Cook Meth N/S15001210, 210, 1, 0.00%, Corn, field, meal-Cooked; Fresh or N/S; Cook MethN/S 1033000, 210, 1, 0.00%, Potato, tuber, w/o peel-Cooked; Fresh or N/S; CookMeth N/S 1033001, 240, 1, 0.00%, Potato, tuber, w/o peel-babyfood-Cooked; Canned;Cook Meth N/S 5023890, 212, 3, 0.00%, Turnip, greens-Cooked; Fresh or N/S; Boiled95003590, 120, 1, 0.00%, Strawberry-Uncooked; Frozen; Cook Meth N/S 8003761, 240, 2, 0.00%, Tomato, paste-babyfood-Cooked; Canned; Cook MethN/S 6030360, 232, 3, 0.00%, Bean, kidney, seed-Cooked; Dried; Boiled 8003750, 211, 2, 0.00%, Tomato-Cooked; Fresh or N/S; Baked 9023571, 240, 2, 0.00%, Squash, winter-babyfood-Cooked; Canned; Cook MethN/S 1010790, 240, 1, 0.00%, Carrot, juice-Cooked; Canned; Cook Meth N/S12002851, 240, 1, 0.00%, Plum-babyfood-Cooked; Canned; Cook Meth N/S 4012040, 110, 2, 0.00%, Lettuce, head-Uncooked; Fresh or N/S; Cook Meth N/S20003650, 900, 1, 0.00%, Sunflower, oil-Refined; FF N/A; Cook Meth N/S 6030300, 232, 2, 0.00%, Bean, black, seed-Cooked; Dried; Boiled95001300, 240, 1, 0.00%, Cranberry-Cooked; Canned; Cook Meth N/S15003230, 232, 1, 0.00%, Rice, white-Cooked; Dried; Boiled15003240, 230, 1, 0.00%, Rice, brown-Cooked; Dried; Cook Meth N/S 6030400, 212, 1, 0.00%, Bean, navy, seed-Cooked; Fresh or N/S; Boiled25002950, 210, 1, 0.00%, Pork, liver-Cooked; Fresh or N/S; Cook Meth N/S27002220, 242, 2, 0.00%, Milk, fat-Cooked; Canned; Boiled95000230, 212, 1, 0.00%, Banana-Cooked; Fresh or N/S; Boiled 8003750, 210, 2, 0.00%, Tomato-Cooked; Fresh or N/S; Cook Meth N/S15004010, 232, 1, 0.00%, Wheat, grain-Cooked; Dried; Boiled11002680, 120, 1, 0.00%, Pear, juice-Uncooked; Frozen; Cook Meth N/S 8002720, 211, 1, 0.00%, Pepper, nonbell-Cooked; Fresh or N/S; Baked15003240, 232, 1, 0.00%, Rice, brown-Cooked; Dried; Boiled 8003770, 213, 1, 0.00%, Tomato, puree-Cooked; Fresh or N/S; Fried 5010830, 110, 1, 0.00%, Cauliflower-Uncooked; Fresh or N/S; Cook Meth N/S 4020860, 240, 1, 0.00%, Celery, juice-Cooked; Canned; Cook Meth N/S 8002710, 110, 1, 0.00%, Pepper, bell, dried-Uncooked; Fresh or N/S; CookMeth N/S21000490, 210, 1, 0.00%, Beef, liver-Cooked; Fresh or N/S; Cook Meth N/S 1033000, 221, 1, 0.00%, Potato, tuber, w/o peel-Cooked; Frozen; Baked15001230, 221, 1, 0.00%, Corn, field, starch-Cooked; Frozen; Baked15003240, 211, 1, 0.00%, Rice, brown-Cooked; Fresh or N/S; Baked 6003481, 230, 1, 0.00%, Soybean, flour-babyfood-Cooked; Dried; Cook MethN/S19012490, 232, 1, 0.00%, Parsley, dried leaves-Cooked; Dried; Boiled95000190, 212, 1, 0.00%, Asparagus-Cooked; Fresh or N/S; Boiled

370

Non-hisp/non-white/non-blackLow percentile for CEC records: 95 Exposure (mg/day) = 0.001058High percentile for CEC records: 100 Exposure (mg/day) = 0.040048Number of actual records in this interval: 1558

Critical foods/foodforms for this population (as derived from these records): N=number of appearances in all records (including duplicates) %=percent of total exposure for all records (including duplicates)

Food, FF, N , Percent, Food Name --------, ---, -----, -------, ------------- 5020700, 210, 386, 20.26%, Cabbage, Chinese, bok choy-Cooked; Fresh or N/S;Cook Meth N/S 5022290, 212, 285, 18.46%, Mustard greens-Cooked; Fresh or N/S; Boiled 5020700, 150, 311, 15.95%, Cabbage, Chinese, bok choy-Uncooked; Cured etc;Cook Meth N/S 4020860, 110, 19, 3.91%, Celery, juice-Uncooked; Fresh or N/S; Cook Meth N/S12000910, 110, 38, 3.86%, Cherry, juice-Uncooked; Fresh or N/S; Cook Meth N/S12002620, 110, 19, 3.67%, Peach, juice-Uncooked; Fresh or N/S; Cook Meth N/S95002810, 110, 98, 3.52%, Pineapple, juice-Uncooked; Fresh or N/S; Cook MethN/S11000070, 110, 55, 3.17%, Apple, fruit with peel-Uncooked; Fresh or N/S; CookMeth N/S12000910, 210, 102, 1.92%, Cherry, juice-Cooked; Fresh or N/S; Cook Meth N/S10001810, 110, 76, 1.85%, Grapefruit, juice-Uncooked; Fresh or N/S; Cook MethN/S 8002720, 110, 60, 1.72%, Pepper, nonbell-Uncooked; Fresh or N/S; Cook MethN/S12002620, 240, 38, 1.61%, Peach, juice-Cooked; Canned; Cook Meth N/S 8002340, 210, 39, 1.03%, Okra-Cooked; Fresh or N/S; Cook Meth N/S13020570, 110, 6, 0.90%, Blueberry-Uncooked; Fresh or N/S; Cook Meth N/S 8002720, 212, 20, 0.79%, Pepper, nonbell-Cooked; Fresh or N/S; Boiled95001750, 110, 18, 0.77%, Grape-Uncooked; Fresh or N/S; Cook Meth N/S10003690, 110, 60, 0.76%, Tangerine-Uncooked; Fresh or N/S; Cook Meth N/S12000911, 240, 19, 0.67%, Cherry, juice-babyfood-Cooked; Canned; Cook MethN/S12002881, 240, 19, 0.62%, Plum, prune, juice-babyfood-Cooked; Canned; CookMeth N/S10003700, 110, 19, 0.61%, Tangerine, juice-Uncooked; Fresh or N/S; Cook MethN/S10001810, 120, 20, 0.60%, Grapefruit, juice-Uncooked; Frozen; Cook Meth N/S11000100, 110, 44, 0.60%, Apple, juice-Uncooked; Fresh or N/S; Cook Meth N/S13013200, 240, 15, 0.59%, Raspberry-Cooked; Canned; Cook Meth N/S11002660, 110, 7, 0.57%, Pear-Uncooked; Fresh or N/S; Cook Meth N/S12002300, 110, 4, 0.49%, Nectarine-Uncooked; Fresh or N/S; Cook Meth N/S10002000, 210, 103, 0.44%, Lemon, juice-Cooked; Fresh or N/S; Cook Meth N/S10003700, 240, 83, 0.41%, Tangerine, juice-Cooked; Canned; Cook Meth N/S10002000, 240, 102, 0.38%, Lemon, juice-Cooked; Canned; Cook Meth N/S12002600, 240, 13, 0.35%, Peach-Cooked; Canned; Cook Meth N/S11000090, 230, 19, 0.31%, Apple, dried-Cooked; Dried; Cook Meth N/S12002601, 240, 4, 0.30%, Peach-babyfood-Cooked; Canned; Cook Meth N/S13020570, 211, 6, 0.25%, Blueberry-Cooked; Fresh or N/S; Baked10002070, 240, 83, 0.25%, Lime, juice-Cooked; Canned; Cook Meth N/S 9020210, 212, 19, 0.25%, Balsam pear-Cooked; Fresh or N/S; Boiled25002930, 210, 158, 0.24%, Pork, fat-Cooked; Fresh or N/S; Cook Meth N/S13010550, 240, 18, 0.22%, Blackberry-Cooked; Canned; Cook Meth N/S13010580, 240, 65, 0.22%, Boysenberry-Cooked; Canned; Cook Meth N/S11002661, 240, 2, 0.19%, Pear-babyfood-Cooked; Canned; Cook Meth N/S27002220, 110, 204, 0.16%, Milk, fat-Uncooked; Fresh or N/S; Cook Meth N/S95002810, 240, 68, 0.15%, Pineapple, juice-Cooked; Canned; Cook Meth N/S95002350, 240, 4, 0.15%, Olive-Cooked; Canned; Cook Meth N/S25002930, 211, 82, 0.14%, Pork, fat-Cooked; Fresh or N/S; Baked12000141, 240, 1, 0.14%, Apricot, juice-babyfood-Cooked; Canned; Cook MethN/S

371

11000110, 212, 22, 0.13%, Apple, sauce-Cooked; Fresh or N/S; Boiled25002930, 213, 121, 0.13%, Pork, fat-Cooked; Fresh or N/S; Fried 8002700, 110, 6, 0.12%, Pepper, bell-Uncooked; Fresh or N/S; Cook Meth N/S10002000, 211, 83, 0.12%, Lemon, juice-Cooked; Fresh or N/S; Baked 8002720, 150, 19, 0.11%, Pepper, nonbell-Uncooked; Cured etc; Cook Meth N/S13010580, 120, 39, 0.11%, Boysenberry-Uncooked; Frozen; Cook Meth N/S95001760, 110, 28, 0.11%, Grape, juice-Uncooked; Fresh or N/S; Cook Meth N/S95002811, 240, 39, 0.10%, Pineapple, juice-babyfood-Cooked; Canned; Cook MethN/S10002000, 110, 8, 0.10%, Lemon, juice-Uncooked; Fresh or N/S; Cook Meth N/S25002900, 210, 116, 0.10%, Pork, meat-Cooked; Fresh or N/S; Cook Meth N/S13020570, 213, 2, 0.10%, Blueberry-Cooked; Fresh or N/S; Fried13020570, 214, 3, 0.09%, Blueberry-Cooked; Fresh or N/S; Fried/baked10001810, 240, 81, 0.09%, Grapefruit, juice-Cooked; Canned; Cook Meth N/S12000900, 211, 2, 0.09%, Cherry-Cooked; Fresh or N/S; Baked12000120, 240, 4, 0.09%, Apricot-Cooked; Canned; Cook Meth N/S25002930, 250, 66, 0.08%, Pork, fat-Cooked; Cured etc; Cook Meth N/S13013210, 110, 1, 0.08%, Raspberry, juice-Uncooked; Fresh or N/S; Cook MethN/S10002000, 130, 20, 0.08%, Lemon, juice-Uncooked; Dried; Cook Meth N/S13020571, 240, 1, 0.08%, Blueberry-babyfood-Cooked; Canned; Cook Meth N/S10002410, 120, 77, 0.08%, Orange, juice-Uncooked; Frozen; Cook Meth N/S 6010430, 242, 3, 0.08%, Bean, snap, succulent-Cooked; Canned; Boiled 8002700, 210, 5, 0.07%, Pepper, bell-Cooked; Fresh or N/S; Cook Meth N/S25002900, 211, 41, 0.07%, Pork, meat-Cooked; Fresh or N/S; Baked 8002730, 210, 25, 0.06%, Pepper, nonbell, dried-Cooked; Fresh or N/S; CookMeth N/S13013200, 110, 4, 0.06%, Raspberry-Uncooked; Fresh or N/S; Cook Meth N/S10002410, 110, 53, 0.06%, Orange, juice-Uncooked; Fresh or N/S; Cook Meth N/S12000910, 240, 24, 0.06%, Cherry, juice-Cooked; Canned; Cook Meth N/S95001750, 210, 8, 0.06%, Grape-Cooked; Fresh or N/S; Cook Meth N/S10003700, 120, 39, 0.06%, Tangerine, juice-Uncooked; Frozen; Cook Meth N/S 9021350, 110, 26, 0.05%, Cucumber-Uncooked; Fresh or N/S; Cook Meth N/S95003590, 110, 6, 0.05%, Strawberry-Uncooked; Fresh or N/S; Cook Meth N/S11000080, 211, 1, 0.05%, Apple, peeled fruit-Cooked; Fresh or N/S; Baked10002000, 120, 39, 0.05%, Lemon, juice-Uncooked; Frozen; Cook Meth N/S21000440, 213, 58, 0.05%, Beef, meat-Cooked; Fresh or N/S; Fried 8002700, 150, 18, 0.05%, Pepper, bell-Uncooked; Cured etc; Cook Meth N/S 8002730, 211, 19, 0.05%, Pepper, nonbell, dried-Cooked; Fresh or N/S; Baked 6010431, 240, 1, 0.04%, Bean, snap, succulent-babyfood-Cooked; Canned; CookMeth N/S10002070, 120, 39, 0.04%, Lime, juice-Uncooked; Frozen; Cook Meth N/S25002900, 250, 62, 0.04%, Pork, meat-Cooked; Cured etc; Cook Meth N/S12000910, 120, 39, 0.04%, Cherry, juice-Uncooked; Frozen; Cook Meth N/S 9010750, 110, 2, 0.04%, Cantaloupe-Uncooked; Fresh or N/S; Cook Meth N/S 8002730, 240, 23, 0.04%, Pepper, nonbell, dried-Cooked; Canned; Cook MethN/S13010560, 120, 1, 0.04%, Blackberry, juice-Uncooked; Frozen; Cook Meth N/S15003250, 230, 13, 0.04%, Rice, flour-Cooked; Dried; Cook Meth N/S 8002720, 240, 41, 0.03%, Pepper, nonbell-Cooked; Canned; Cook Meth N/S11000081, 240, 1, 0.03%, Apple, peeled fruit-babyfood-Cooked; Canned; CookMeth N/S11002660, 240, 2, 0.03%, Pear-Cooked; Canned; Cook Meth N/S 8002720, 210, 20, 0.03%, Pepper, nonbell-Cooked; Fresh or N/S; Cook Meth N/S13013211, 240, 1, 0.03%, Raspberry, juice-babyfood-Cooked; Canned; Cook MethN/S15001210, 233, 38, 0.03%, Corn, field, meal-Cooked; Dried; Fried95002350, 211, 1, 0.03%, Olive-Cooked; Fresh or N/S; Baked11000100, 120, 2, 0.03%, Apple, juice-Uncooked; Frozen; Cook Meth N/S95001750, 240, 5, 0.03%, Grape-Cooked; Canned; Cook Meth N/S12000120, 110, 1, 0.03%, Apricot-Uncooked; Fresh or N/S; Cook Meth N/S11000091, 230, 1, 0.03%, Apple, dried-babyfood-Cooked; Dried; Cook Meth N/S15001240, 240, 32, 0.02%, Corn, field, syrup-Cooked; Canned; Cook Meth N/S95001760, 240, 39, 0.02%, Grape, juice-Cooked; Canned; Cook Meth N/S13020570, 240, 1, 0.02%, Blueberry-Cooked; Canned; Cook Meth N/S

372

95003590, 240, 3, 0.02%, Strawberry-Cooked; Canned; Cook Meth N/S 5020700, 110, 1, 0.02%, Cabbage, Chinese, bok choy-Uncooked; Fresh or N/S;Cook Meth N/S21000440, 210, 25, 0.02%, Beef, meat-Cooked; Fresh or N/S; Cook Meth N/S 8002700, 213, 4, 0.02%, Pepper, bell-Cooked; Fresh or N/S; Fried25002930, 212, 22, 0.02%, Pork, fat-Cooked; Fresh or N/S; Boiled25002900, 213, 22, 0.02%, Pork, meat-Cooked; Fresh or N/S; Fried11000101, 240, 22, 0.02%, Apple, juice-babyfood-Cooked; Canned; Cook Meth N/S95003600, 210, 2, 0.02%, Strawberry, juice-Cooked; Fresh or N/S; Cook MethN/S21000470, 213, 20, 0.02%, Beef, fat-Cooked; Fresh or N/S; Fried 8003770, 240, 19, 0.02%, Tomato, puree-Cooked; Canned; Cook Meth N/S13013210, 240, 5, 0.01%, Raspberry, juice-Cooked; Canned; Cook Meth N/S27002220, 211, 20, 0.01%, Milk, fat-Cooked; Fresh or N/S; Baked11002660, 210, 3, 0.01%, Pear-Cooked; Fresh or N/S; Cook Meth N/S 8002720, 230, 1, 0.01%, Pepper, nonbell-Cooked; Dried; Cook Meth N/S15004020, 211, 27, 0.01%, Wheat, flour-Cooked; Fresh or N/S; Baked12002600, 110, 3, 0.01%, Peach-Uncooked; Fresh or N/S; Cook Meth N/S 4012480, 210, 21, 0.01%, Parsley, leaves-Cooked; Fresh or N/S; Cook Meth N/S11000111, 240, 2, 0.01%, Apple, sauce-babyfood-Cooked; Canned; Cook Meth N/S15004020, 210, 19, 0.01%, Wheat, flour-Cooked; Fresh or N/S; Cook Meth N/S15001240, 210, 19, 0.01%, Corn, field, syrup-Cooked; Fresh or N/S; Cook MethN/S 8002720, 213, 19, 0.01%, Pepper, nonbell-Cooked; Fresh or N/S; Fried 1013140, 110, 19, 0.01%, Radish, roots-Uncooked; Fresh or N/S; Cook Meth N/S 8003770, 212, 18, 0.01%, Tomato, puree-Cooked; Fresh or N/S; Boiled10002400, 110, 2, 0.01%, Orange-Uncooked; Fresh or N/S; Cook Meth N/S12000900, 110, 2, 0.01%, Cherry-Uncooked; Fresh or N/S; Cook Meth N/S27002220, 120, 16, 0.01%, Milk, fat-Uncooked; Frozen; Cook Meth N/S13010550, 120, 3, 0.01%, Blackberry-Uncooked; Frozen; Cook Meth N/S10002410, 240, 4, 0.01%, Orange, juice-Cooked; Canned; Cook Meth N/S11000100, 240, 4, 0.01%, Apple, juice-Cooked; Canned; Cook Meth N/S15003240, 210, 1, 0.01%, Rice, brown-Cooked; Fresh or N/S; Cook Meth N/S21000470, 210, 5, 0.01%, Beef, fat-Cooked; Fresh or N/S; Cook Meth N/S 1010790, 240, 4, 0.01%, Carrot, juice-Cooked; Canned; Cook Meth N/S25002930, 240, 1, 0.00%, Pork, fat-Cooked; Canned; Cook Meth N/S25002930, 230, 4, 0.00%, Pork, fat-Cooked; Dried; Cook Meth N/S15004020, 232, 7, 0.00%, Wheat, flour-Cooked; Dried; Boiled 8003770, 210, 6, 0.00%, Tomato, puree-Cooked; Fresh or N/S; Cook Meth N/S15003250, 232, 1, 0.00%, Rice, flour-Cooked; Dried; Boiled 8002730, 212, 3, 0.00%, Pepper, nonbell, dried-Cooked; Fresh or N/S; Boiled 8001480, 214, 2, 0.00%, Eggplant-Cooked; Fresh or N/S; Fried/baked10001990, 110, 2, 0.00%, Lemon-Uncooked; Fresh or N/S; Cook Meth N/S95003600, 240, 2, 0.00%, Strawberry, juice-Cooked; Canned; Cook Meth N/S 4011500, 110, 4, 0.00%, Endive-Uncooked; Fresh or N/S; Cook Meth N/S15001200, 230, 6, 0.00%, Corn, field, flour-Cooked; Dried; Cook Meth N/S 8002700, 212, 1, 0.00%, Pepper, bell-Cooked; Fresh or N/S; Boiled25002930, 221, 1, 0.00%, Pork, fat-Cooked; Frozen; Baked95001320, 110, 1, 0.00%, Cranberry, juice-Uncooked; Fresh or N/S; Cook MethN/S15001241, 240, 2, 0.00%, Corn, field, syrup-babyfood-Cooked; Canned; CookMeth N/S15001231, 130, 2, 0.00%, Corn, field, starch-babyfood-Uncooked; Dried; CookMeth N/S 9011870, 110, 1, 0.00%, Honeydew melon-Uncooked; Fresh or N/S; Cook MethN/S25002930, 253, 2, 0.00%, Pork, fat-Cooked; Cured etc; Fried14003910, 211, 1, 0.00%, Walnut-Cooked; Fresh or N/S; Baked12002850, 110, 1, 0.00%, Plum-Uncooked; Fresh or N/S; Cook Meth N/S95001760, 210, 2, 0.00%, Grape, juice-Cooked; Fresh or N/S; Cook Meth N/S15001240, 110, 3, 0.00%, Corn, field, syrup-Uncooked; Fresh or N/S; CookMeth N/S95002790, 240, 2, 0.00%, Pineapple-Cooked; Canned; Cook Meth N/S12000900, 240, 2, 0.00%, Cherry-Cooked; Canned; Cook Meth N/S13020570, 120, 1, 0.00%, Blueberry-Uncooked; Frozen; Cook Meth N/S

373

15003251, 230, 1, 0.00%, Rice, flour-babyfood-Cooked; Dried; Cook Meth N/S21000470, 250, 3, 0.00%, Beef, fat-Cooked; Cured etc; Cook Meth N/S13013210, 120, 2, 0.00%, Raspberry, juice-Uncooked; Frozen; Cook Meth N/S13013200, 211, 1, 0.00%, Raspberry-Cooked; Fresh or N/S; Baked95002640, 210, 3, 0.00%, Peanut, butter-Cooked; Fresh or N/S; Cook Meth N/S95000230, 110, 3, 0.00%, Banana-Uncooked; Fresh or N/S; Cook Meth N/S10002070, 110, 1, 0.00%, Lime, juice-Uncooked; Fresh or N/S; Cook Meth N/S 4013551, 240, 1, 0.00%, Spinach-babyfood-Cooked; Canned; Cook Meth N/S27002220, 232, 3, 0.00%, Milk, fat-Cooked; Dried; Boiled15003240, 232, 1, 0.00%, Rice, brown-Cooked; Dried; Boiled15001200, 210, 1, 0.00%, Corn, field, flour-Cooked; Fresh or N/S; Cook MethN/S15001200, 214, 2, 0.00%, Corn, field, flour-Cooked; Fresh or N/S;Fried/baked27002220, 212, 2, 0.00%, Milk, fat-Cooked; Fresh or N/S; Boiled10002000, 212, 1, 0.00%, Lemon, juice-Cooked; Fresh or N/S; Boiled23001690, 212, 1, 0.00%, Goat, meat-Cooked; Fresh or N/S; Boiled20003640, 211, 1, 0.00%, Sunflower, seed-Cooked; Fresh or N/S; Baked15003251, 240, 2, 0.00%, Rice, flour-babyfood-Cooked; Canned; Cook Meth N/S 1030820, 231, 1, 0.00%, Cassava-Cooked; Dried; Baked15001240, 212, 2, 0.00%, Corn, field, syrup-Cooked; Fresh or N/S; Boiled21000470, 212, 1, 0.00%, Beef, fat-Cooked; Fresh or N/S; Boiled25002931, 240, 1, 0.00%, Pork, fat-babyfood-Cooked; Canned; Cook Meth N/S25002900, 240, 1, 0.00%, Pork, meat-Cooked; Canned; Cook Meth N/S 6030420, 232, 1, 0.00%, Bean, pinto, seed-Cooked; Dried; Boiled25002920, 210, 1, 0.00%, Pork, meat byproducts-Cooked; Fresh or N/S; CookMeth N/S95002810, 120, 1, 0.00%, Pineapple, juice-Uncooked; Frozen; Cook Meth N/S95001320, 240, 1, 0.00%, Cranberry, juice-Cooked; Canned; Cook Meth N/S25002901, 240, 1, 0.00%, Pork, meat-babyfood-Cooked; Canned; Cook Meth N/S 9021350, 240, 1, 0.00%, Cucumber-Cooked; Canned; Cook Meth N/S 1033000, 212, 1, 0.00%, Potato, tuber, w/o peel-Cooked; Fresh or N/S;Boiled15004011, 230, 1, 0.00%, Wheat, grain-babyfood-Cooked; Dried; Cook Meth N/S20003650, 900, 1, 0.00%, Sunflower, oil-Refined; FF N/A; Cook Meth N/S21000440, 212, 1, 0.00%, Beef, meat-Cooked; Fresh or N/S; Boiled 5010830, 212, 1, 0.00%, Cauliflower-Cooked; Fresh or N/S; Boiled27002220, 210, 1, 0.00%, Milk, fat-Cooked; Fresh or N/S; Cook Meth N/S 8002730, 213, 1, 0.00%, Pepper, nonbell, dried-Cooked; Fresh or N/S; Fried95001761, 240, 1, 0.00%, Grape, juice-babyfood-Cooked; Canned; Cook Meth N/S15001210, 230, 1, 0.00%, Corn, field, meal-Cooked; Dried; Cook Meth N/S

374

All infantsLow percentile for CEC records: 95 Exposure (mg/day) = 0.000612High percentile for CEC records: 100 Exposure (mg/day) = 0.157992Number of actual records in this interval: 2615

Critical foods/foodforms for this population (as derived from these records): N=number of appearances in all records (including duplicates) %=percent of total exposure for all records (including duplicates)

Food, FF, N , Percent, Food Name --------, ---, -----, -------, -------------12000911, 240, 722, 14.47%, Cherry, juice-babyfood-Cooked; Canned; Cook MethN/S12002881, 240, 342, 11.82%, Plum, prune, juice-babyfood-Cooked; Canned; CookMeth N/S12002880, 110, 76, 10.08%, Plum, prune, juice-Uncooked; Fresh or N/S; CookMeth N/S12002601, 240, 194, 5.67%, Peach-babyfood-Cooked; Canned; Cook Meth N/S12000910, 110, 19, 5.32%, Cherry, juice-Uncooked; Fresh or N/S; Cook Meth N/S13020571, 240, 77, 4.93%, Blueberry-babyfood-Cooked; Canned; Cook Meth N/S12002621, 240, 171, 3.63%, Peach, juice-babyfood-Cooked; Canned; Cook Meth N/S15003251, 230, 999, 3.51%, Rice, flour-babyfood-Cooked; Dried; Cook Meth N/S95002810, 110, 116, 2.81%, Pineapple, juice-Uncooked; Fresh or N/S; Cook MethN/S11002661, 240, 80, 2.65%, Pear-babyfood-Cooked; Canned; Cook Meth N/S10001810, 240, 67, 2.43%, Grapefruit, juice-Cooked; Canned; Cook Meth N/S95002811, 240, 469, 2.25%, Pineapple, juice-babyfood-Cooked; Canned; Cook MethN/S10001810, 110, 21, 2.06%, Grapefruit, juice-Uncooked; Fresh or N/S; Cook MethN/S11000111, 240, 445, 2.04%, Apple, sauce-babyfood-Cooked; Canned; Cook Meth N/S11000101, 240, 867, 1.77%, Apple, juice-babyfood-Cooked; Canned; Cook Meth N/S95002810, 240, 118, 1.66%, Pineapple, juice-Cooked; Canned; Cook Meth N/S11000081, 240, 81, 1.49%, Apple, peeled fruit-babyfood-Cooked; Canned; CookMeth N/S 8002340, 220, 38, 1.23%, Okra-Cooked; Frozen; Cook Meth N/S12000910, 210, 40, 1.19%, Cherry, juice-Cooked; Fresh or N/S; Cook Meth N/S11000091, 230, 119, 1.11%, Apple, dried-babyfood-Cooked; Dried; Cook Meth N/S15003251, 240, 617, 1.00%, Rice, flour-babyfood-Cooked; Canned; Cook Meth N/S12000121, 240, 110, 0.93%, Apricot-babyfood-Cooked; Canned; Cook Meth N/S12000141, 240, 68, 0.73%, Apricot, juice-babyfood-Cooked; Canned; Cook MethN/S 8002340, 210, 19, 0.72%, Okra-Cooked; Fresh or N/S; Cook Meth N/S10003700, 110, 19, 0.72%, Tangerine, juice-Uncooked; Fresh or N/S; Cook MethN/S13013201, 240, 47, 0.72%, Raspberry-babyfood-Cooked; Canned; Cook Meth N/S11000070, 110, 30, 0.69%, Apple, fruit with peel-Uncooked; Fresh or N/S; CookMeth N/S10002001, 240, 215, 0.67%, Lemon, juice-babyfood-Cooked; Canned; Cook Meth N/S11000100, 110, 176, 0.66%, Apple, juice-Uncooked; Fresh or N/S; Cook Meth N/S10003690, 110, 19, 0.63%, Tangerine-Uncooked; Fresh or N/S; Cook Meth N/S95001761, 240, 126, 0.53%, Grape, juice-babyfood-Cooked; Canned; Cook Meth N/S11000110, 212, 71, 0.47%, Apple, sauce-Cooked; Fresh or N/S; Boiled95001760, 240, 89, 0.39%, Grape, juice-Cooked; Canned; Cook Meth N/S13020570, 110, 14, 0.36%, Blueberry-Uncooked; Fresh or N/S; Cook Meth N/S 6010431, 240, 16, 0.34%, Bean, snap, succulent-babyfood-Cooked; Canned; CookMeth N/S12000901, 240, 26, 0.33%, Cherry-babyfood-Cooked; Canned; Cook Meth N/S12002600, 110, 18, 0.32%, Peach-Uncooked; Fresh or N/S; Cook Meth N/S11000090, 211, 66, 0.31%, Apple, dried-Cooked; Fresh or N/S; Baked95001750, 110, 11, 0.29%, Grape-Uncooked; Fresh or N/S; Cook Meth N/S10003700, 240, 68, 0.29%, Tangerine, juice-Cooked; Canned; Cook Meth N/S11002681, 240, 15, 0.27%, Pear, juice-babyfood-Cooked; Canned; Cook Meth N/S10002000, 210, 40, 0.27%, Lemon, juice-Cooked; Fresh or N/S; Cook Meth N/S

375

11000100, 240, 82, 0.26%, Apple, juice-Cooked; Canned; Cook Meth N/S10002000, 240, 67, 0.25%, Lemon, juice-Cooked; Canned; Cook Meth N/S13010561, 240, 6, 0.23%, Blackberry, juice-babyfood-Cooked; Canned; CookMeth N/S10002070, 240, 67, 0.20%, Lime, juice-Cooked; Canned; Cook Meth N/S27002220, 110, 309, 0.17%, Milk, fat-Uncooked; Fresh or N/S; Cook Meth N/S20003651, 900, 440, 0.15%, Sunflower, oil-babyfood-Refined; FF N/A; Cook MethN/S 4013551, 240, 13, 0.14%, Spinach-babyfood-Cooked; Canned; Cook Meth N/S 1030821, 240, 287, 0.14%, Cassava-babyfood-Cooked; Canned; Cook Meth N/S10002000, 110, 19, 0.14%, Lemon, juice-Uncooked; Fresh or N/S; Cook Meth N/S15001241, 240, 181, 0.13%, Corn, field, syrup-babyfood-Cooked; Canned; CookMeth N/S13013211, 240, 6, 0.11%, Raspberry, juice-babyfood-Cooked; Canned; Cook MethN/S12000900, 110, 7, 0.11%, Cherry-Uncooked; Fresh or N/S; Cook Meth N/S25002930, 210, 74, 0.10%, Pork, fat-Cooked; Fresh or N/S; Cook Meth N/S11002660, 110, 2, 0.10%, Pear-Uncooked; Fresh or N/S; Cook Meth N/S15001241, 130, 115, 0.10%, Corn, field, syrup-babyfood-Uncooked; Dried; CookMeth N/S15001241, 230, 120, 0.10%, Corn, field, syrup-babyfood-Cooked; Dried; CookMeth N/S15001231, 240, 274, 0.09%, Corn, field, starch-babyfood-Cooked; Canned; CookMeth N/S95001760, 110, 22, 0.09%, Grape, juice-Uncooked; Fresh or N/S; Cook Meth N/S21000441, 240, 172, 0.08%, Beef, meat-babyfood-Cooked; Canned; Cook Meth N/S25002931, 240, 110, 0.08%, Pork, fat-babyfood-Cooked; Canned; Cook Meth N/S12002600, 240, 5, 0.08%, Peach-Cooked; Canned; Cook Meth N/S 1033661, 240, 87, 0.07%, Sweet potato-babyfood-Cooked; Canned; Cook Meth N/S11002660, 240, 5, 0.07%, Pear-Cooked; Canned; Cook Meth N/S 8002720, 212, 43, 0.07%, Pepper, nonbell-Cooked; Fresh or N/S; Boiled11000080, 211, 3, 0.06%, Apple, peeled fruit-Cooked; Fresh or N/S; Baked10002410, 110, 76, 0.06%, Orange, juice-Uncooked; Fresh or N/S; Cook Meth N/S13013200, 240, 5, 0.06%, Raspberry-Cooked; Canned; Cook Meth N/S13010580, 240, 30, 0.06%, Boysenberry-Cooked; Canned; Cook Meth N/S13010550, 110, 2, 0.05%, Blackberry-Uncooked; Fresh or N/S; Cook Meth N/S12002851, 240, 15, 0.05%, Plum-babyfood-Cooked; Canned; Cook Meth N/S10002410, 240, 72, 0.04%, Orange, juice-Cooked; Canned; Cook Meth N/S25002901, 240, 84, 0.04%, Pork, meat-babyfood-Cooked; Canned; Cook Meth N/S25002930, 240, 25, 0.04%, Pork, fat-Cooked; Canned; Cook Meth N/S15003240, 210, 20, 0.04%, Rice, brown-Cooked; Fresh or N/S; Cook Meth N/S11002660, 210, 3, 0.04%, Pear-Cooked; Fresh or N/S; Cook Meth N/S25002930, 213, 64, 0.04%, Pork, fat-Cooked; Fresh or N/S; Fried11000110, 210, 5, 0.04%, Apple, sauce-Cooked; Fresh or N/S; Cook Meth N/S15001231, 130, 79, 0.04%, Corn, field, starch-babyfood-Uncooked; Dried; CookMeth N/S11002680, 240, 1, 0.04%, Pear, juice-Cooked; Canned; Cook Meth N/S13010550, 240, 5, 0.03%, Blackberry-Cooked; Canned; Cook Meth N/S12002861, 240, 6, 0.03%, Plum, prune, fresh-babyfood-Cooked; Canned; CookMeth N/S13013200, 110, 3, 0.03%, Raspberry-Uncooked; Fresh or N/S; Cook Meth N/S95002350, 211, 2, 0.03%, Olive-Cooked; Fresh or N/S; Baked95000230, 110, 94, 0.02%, Banana-Uncooked; Fresh or N/S; Cook Meth N/S 9010750, 110, 2, 0.02%, Cantaloupe-Uncooked; Fresh or N/S; Cook Meth N/S12002600, 210, 2, 0.02%, Peach-Cooked; Fresh or N/S; Cook Meth N/S95003600, 240, 1, 0.02%, Strawberry, juice-Cooked; Canned; Cook Meth N/S 8002700, 215, 5, 0.02%, Pepper, bell-Cooked; Fresh or N/S; Boiled/baked15004020, 211, 71, 0.02%, Wheat, flour-Cooked; Fresh or N/S; Baked12000910, 240, 29, 0.02%, Cherry, juice-Cooked; Canned; Cook Meth N/S25002930, 232, 20, 0.02%, Pork, fat-Cooked; Dried; Boiled 8002730, 210, 10, 0.02%, Pepper, nonbell, dried-Cooked; Fresh or N/S; CookMeth N/S 8002730, 240, 24, 0.02%, Pepper, nonbell, dried-Cooked; Canned; Cook MethN/S25002930, 250, 24, 0.02%, Pork, fat-Cooked; Cured etc; Cook Meth N/S

376

15001240, 240, 50, 0.02%, Corn, field, syrup-Cooked; Canned; Cook Meth N/S21000470, 210, 32, 0.02%, Beef, fat-Cooked; Fresh or N/S; Cook Meth N/S 9023080, 211, 19, 0.01%, Pumpkin-Cooked; Fresh or N/S; Baked10002071, 240, 37, 0.01%, Lime, juice-babyfood-Cooked; Canned; Cook Meth N/S 8003770, 240, 43, 0.01%, Tomato, puree-Cooked; Canned; Cook Meth N/S95001750, 210, 2, 0.01%, Grape-Cooked; Fresh or N/S; Cook Meth N/S21000471, 240, 45, 0.01%, Beef,fat-babyfood-Cooked; Canned; Cook Meth N/S95001760, 120, 1, 0.01%, Grape, juice-Uncooked; Frozen; Cook Meth N/S25002900, 250, 23, 0.01%, Pork, meat-Cooked; Cured etc; Cook Meth N/S25002930, 212, 21, 0.01%, Pork, fat-Cooked; Fresh or N/S; Boiled10002411, 240, 28, 0.01%, Orange, juice-babyfood-Cooked; Canned; Cook MethN/S 1010790, 240, 24, 0.01%, Carrot, juice-Cooked; Canned; Cook Meth N/S12002300, 110, 1, 0.01%, Nectarine-Uncooked; Fresh or N/S; Cook Meth N/S15001210, 233, 39, 0.01%, Corn, field, meal-Cooked; Dried; Fried13020570, 210, 1, 0.01%, Blueberry-Cooked; Fresh or N/S; Cook Meth N/S15001210, 230, 22, 0.01%, Corn, field, meal-Cooked; Dried; Cook Meth N/S 1033000, 212, 9, 0.01%, Potato, tuber, w/o peel-Cooked; Fresh or N/S;Boiled 6010430, 242, 1, 0.01%, Bean, snap, succulent-Cooked; Canned; Boiled27002220, 230, 20, 0.01%, Milk, fat-Cooked; Dried; Cook Meth N/S15001200, 214, 19, 0.01%, Corn, field, flour-Cooked; Fresh or N/S;Fried/baked 6032560, 232, 18, 0.01%, Pea, dry-Cooked; Dried; Boiled12002850, 110, 3, 0.01%, Plum-Uncooked; Fresh or N/S; Cook Meth N/S15004020, 232, 15, 0.01%, Wheat, flour-Cooked; Dried; Boiled15001200, 230, 21, 0.01%, Corn, field, flour-Cooked; Dried; Cook Meth N/S13020570, 240, 3, 0.01%, Blueberry-Cooked; Canned; Cook Meth N/S25002900, 240, 21, 0.01%, Pork, meat-Cooked; Canned; Cook Meth N/S15004011, 230, 19, 0.01%, Wheat, grain-babyfood-Cooked; Dried; Cook Meth N/S15001201, 230, 31, 0.01%, Corn, field, flour-babyfood-Cooked; Dried; CookMeth N/S15004020, 231, 19, 0.01%, Wheat, flour-Cooked; Dried; Baked21000440, 214, 20, 0.01%, Beef, meat-Cooked; Fresh or N/S; Fried/baked10002410, 120, 4, 0.01%, Orange, juice-Uncooked; Frozen; Cook Meth N/S21000440, 213, 19, 0.01%, Beef, meat-Cooked; Fresh or N/S; Fried 8002720, 210, 1, 0.01%, Pepper, nonbell-Cooked; Fresh or N/S; Cook Meth N/S21000470, 213, 19, 0.01%, Beef, fat-Cooked; Fresh or N/S; Fried27002220, 232, 7, 0.01%, Milk, fat-Cooked; Dried; Boiled15001240, 110, 17, 0.01%, Corn, field, syrup-Uncooked; Fresh or N/S; CookMeth N/S21000440, 211, 7, 0.00%, Beef, meat-Cooked; Fresh or N/S; Baked 1033000, 211, 2, 0.00%, Potato, tuber, w/o peel-Cooked; Fresh or N/S; Baked 8002700, 211, 2, 0.00%, Pepper, bell-Cooked; Fresh or N/S; Baked 8002730, 212, 8, 0.00%, Pepper, nonbell, dried-Cooked; Fresh or N/S; Boiled21000440, 210, 9, 0.00%, Beef, meat-Cooked; Fresh or N/S; Cook Meth N/S10001990, 110, 2, 0.00%, Lemon-Uncooked; Fresh or N/S; Cook Meth N/S 4012480, 210, 8, 0.00%, Parsley, leaves-Cooked; Fresh or N/S; Cook Meth N/S 1010781, 240, 15, 0.00%, Carrot-babyfood-Cooked; Canned; Cook Meth N/S 8002720, 215, 4, 0.00%, Pepper, nonbell-Cooked; Fresh or N/S; Boiled/baked25002930, 253, 3, 0.00%, Pork, fat-Cooked; Cured etc; Fried 8003770, 210, 5, 0.00%, Tomato, puree-Cooked; Fresh or N/S; Cook Meth N/S15003250, 230, 6, 0.00%, Rice, flour-Cooked; Dried; Cook Meth N/S95002360, 900, 6, 0.00%, Olive, oil-Refined; FF N/A; Cook Meth N/S 9023571, 240, 11, 0.00%, Squash, winter-babyfood-Cooked; Canned; Cook MethN/S 8003790, 212, 2, 0.00%, Tomato, juice-Cooked; Fresh or N/S; Boiled 6003481, 240, 13, 0.00%, Soybean, flour-babyfood-Cooked; Canned; Cook MethN/S 8003760, 210, 9, 0.00%, Tomato, paste-Cooked; Fresh or N/S; Cook Meth N/S21000470, 211, 4, 0.00%, Beef, fat-Cooked; Fresh or N/S; Baked10002000, 211, 4, 0.00%, Lemon, juice-Cooked; Fresh or N/S; Baked26003391, 240, 6, 0.00%, Sheep, meat-babyfood-Cooked; Canned; Cook Meth N/S 9023560, 212, 5, 0.00%, Squash, summer-Cooked; Fresh or N/S; Boiled 8003770, 212, 4, 0.00%, Tomato, puree-Cooked; Fresh or N/S; Boiled

377

8003750, 212, 5, 0.00%, Tomato-Cooked; Fresh or N/S; Boiled27002220, 211, 5, 0.00%, Milk, fat-Cooked; Fresh or N/S; Baked15004020, 210, 7, 0.00%, Wheat, flour-Cooked; Fresh or N/S; Cook Meth N/S27022240, 110, 10, 0.00%, Milk, water-Uncooked; Fresh or N/S; Cook Meth N/S 1010501, 240, 2, 0.00%, Beet, garden, roots-babyfood-Cooked; Canned; CookMeth N/S95002790, 110, 4, 0.00%, Pineapple-Uncooked; Fresh or N/S; Cook Meth N/S 8002711, 240, 1, 0.00%, Pepper, bell, dried-babyfood-Cooked; Canned; CookMeth N/S 9013990, 110, 2, 0.00%, Watermelon-Uncooked; Fresh or N/S; Cook Meth N/S 1010790, 110, 1, 0.00%, Carrot, juice-Uncooked; Fresh or N/S; Cook Meth N/S12000140, 240, 1, 0.00%, Apricot, juice-Cooked; Canned; Cook Meth N/S11000100, 210, 2, 0.00%, Apple, juice-Cooked; Fresh or N/S; Cook Meth N/S95002791, 240, 2, 0.00%, Pineapple-babyfood-Cooked; Canned; Cook Meth N/S 6032030, 232, 5, 0.00%, Lentil, seed-Cooked; Dried; Boiled13013210, 240, 1, 0.00%, Raspberry, juice-Cooked; Canned; Cook Meth N/S 6003481, 230, 6, 0.00%, Soybean, flour-babyfood-Cooked; Dried; Cook MethN/S25002900, 213, 1, 0.00%, Pork, meat-Cooked; Fresh or N/S; Fried 8002730, 232, 4, 0.00%, Pepper, nonbell, dried-Cooked; Dried; Boiled10001800, 110, 2, 0.00%, Grapefruit-Uncooked; Fresh or N/S; Cook Meth N/S 8002720, 240, 2, 0.00%, Pepper, nonbell-Cooked; Canned; Cook Meth N/S 1033001, 240, 2, 0.00%, Potato, tuber, w/o peel-babyfood-Cooked; Canned;Cook Meth N/S 1010780, 212, 3, 0.00%, Carrot-Cooked; Fresh or N/S; Boiled15004011, 240, 6, 0.00%, Wheat, grain-babyfood-Cooked; Canned; Cook Meth N/S15001240, 212, 4, 0.00%, Corn, field, syrup-Cooked; Fresh or N/S; Boiled15001240, 130, 2, 0.00%, Corn, field, syrup-Uncooked; Dried; Cook Meth N/S95001760, 210, 1, 0.00%, Grape, juice-Cooked; Fresh or N/S; Cook Meth N/S25002930, 211, 2, 0.00%, Pork, fat-Cooked; Fresh or N/S; Baked95003601, 240, 1, 0.00%, Strawberry, juice-babyfood-Cooked; Canned; CookMeth N/S95002640, 210, 3, 0.00%, Peanut, butter-Cooked; Fresh or N/S; Cook Meth N/S27002220, 213, 2, 0.00%, Milk, fat-Cooked; Fresh or N/S; Fried21000440, 212, 2, 0.00%, Beef, meat-Cooked; Fresh or N/S; Boiled15004020, 212, 3, 0.00%, Wheat, flour-Cooked; Fresh or N/S; Boiled21000470, 212, 2, 0.00%, Beef, fat-Cooked; Fresh or N/S; Boiled95002810, 211, 1, 0.00%, Pineapple, juice-Cooked; Fresh or N/S; Baked25002900, 210, 2, 0.00%, Pork, meat-Cooked; Fresh or N/S; Cook Meth N/S 1032981, 240, 2, 0.00%, Potato, flour-babyfood-Cooked; Canned; Cook MethN/S 8003790, 240, 1, 0.00%, Tomato, juice-Cooked; Canned; Cook Meth N/S 9011870, 110, 1, 0.00%, Honeydew melon-Uncooked; Fresh or N/S; Cook MethN/S 1030820, 231, 1, 0.00%, Cassava-Cooked; Dried; Baked15001241, 110, 3, 0.00%, Corn, field, syrup-babyfood-Uncooked; Fresh or N/S;Cook Meth N/S10002000, 130, 1, 0.00%, Lemon, juice-Uncooked; Dried; Cook Meth N/S21000470, 240, 2, 0.00%, Beef, fat-Cooked; Canned; Cook Meth N/S27002220, 215, 2, 0.00%, Milk, fat-Cooked; Fresh or N/S; Boiled/baked 1033660, 211, 1, 0.00%, Sweet potato-Cooked; Fresh or N/S; Baked15001210, 232, 2, 0.00%, Corn, field, meal-Cooked; Dried; Boiled15004010, 211, 2, 0.00%, Wheat, grain-Cooked; Fresh or N/S; Baked 5010830, 212, 1, 0.00%, Cauliflower-Cooked; Fresh or N/S; Boiled15004020, 230, 2, 0.00%, Wheat, flour-Cooked; Dried; Cook Meth N/S11000090, 230, 1, 0.00%, Apple, dried-Cooked; Dried; Cook Meth N/S13010580, 120, 2, 0.00%, Boysenberry-Uncooked; Frozen; Cook Meth N/S25002900, 211, 1, 0.00%, Pork, meat-Cooked; Fresh or N/S; Baked15001260, 211, 2, 0.00%, Corn, pop-Cooked; Fresh or N/S; Baked27002220, 210, 1, 0.00%, Milk, fat-Cooked; Fresh or N/S; Cook Meth N/S15004020, 215, 1, 0.00%, Wheat, flour-Cooked; Fresh or N/S; Boiled/baked 8003750, 215, 1, 0.00%, Tomato-Cooked; Fresh or N/S; Boiled/baked15001240, 211, 2, 0.00%, Corn, field, syrup-Cooked; Fresh or N/S; Baked 6003481, 130, 2, 0.00%, Soybean, flour-babyfood-Uncooked; Dried; Cook MethN/S

378

8003761, 240, 2, 0.00%, Tomato, paste-babyfood-Cooked; Canned; Cook MethN/S95003590, 211, 1, 0.00%, Strawberry-Cooked; Fresh or N/S; Baked10002070, 120, 1, 0.00%, Lime, juice-Uncooked; Frozen; Cook Meth N/S 8003771, 240, 1, 0.00%, Tomato, puree-babyfood-Cooked; Canned; Cook MethN/S15003241, 240, 1, 0.00%, Rice, brown-babyfood-Cooked; Canned; Cook Meth N/S15004010, 232, 1, 0.00%, Wheat, grain-Cooked; Dried; Boiled25002900, 212, 1, 0.00%, Pork, meat-Cooked; Fresh or N/S; Boiled21000440, 240, 1, 0.00%, Beef, meat-Cooked; Canned; Cook Meth N/S27002220, 120, 1, 0.00%, Milk, fat-Uncooked; Frozen; Cook Meth N/S 4020860, 240, 1, 0.00%, Celery, juice-Cooked; Canned; Cook Meth N/S15004021, 240, 1, 0.00%, Wheat, flour-babyfood-Cooked; Canned; Cook Meth N/S15004010, 230, 1, 0.00%, Wheat, grain-Cooked; Dried; Cook Meth N/S 8003770, 211, 1, 0.00%, Tomato, puree-Cooked; Fresh or N/S; Baked

379

Nursing infants (<1 yr old)Low percentile for CEC records: 95 Exposure (mg/day) = 0.000302High percentile for CEC records: 100 Exposure (mg/day) = 0.072624Number of actual records in this interval: 807

Critical foods/foodforms for this population (as derived from these records): N=number of appearances in all records (including duplicates) %=percent of total exposure for all records (including duplicates)

Food, FF, N , Percent, Food Name --------, ---, -----, -------, -------------12000911, 240, 136, 17.16%, Cherry, juice-babyfood-Cooked; Canned; Cook MethN/S15003251, 230, 428, 8.69%, Rice, flour-babyfood-Cooked; Dried; Cook Meth N/S13020571, 240, 25, 7.33%, Blueberry-babyfood-Cooked; Canned; Cook Meth N/S12002601, 240, 44, 7.07%, Peach-babyfood-Cooked; Canned; Cook Meth N/S95002811, 240, 142, 5.21%, Pineapple, juice-babyfood-Cooked; Canned; Cook MethN/S12002881, 240, 19, 4.50%, Plum, prune, juice-babyfood-Cooked; Canned; CookMeth N/S11000111, 240, 168, 3.75%, Apple, sauce-babyfood-Cooked; Canned; Cook Meth N/S11000081, 240, 28, 3.28%, Apple, peeled fruit-babyfood-Cooked; Canned; CookMeth N/S11002661, 240, 20, 3.12%, Pear-babyfood-Cooked; Canned; Cook Meth N/S11000091, 230, 59, 2.66%, Apple, dried-babyfood-Cooked; Dried; Cook Meth N/S11000101, 240, 230, 2.62%, Apple, juice-babyfood-Cooked; Canned; Cook Meth N/S95002810, 240, 20, 2.38%, Pineapple, juice-Cooked; Canned; Cook Meth N/S95002810, 110, 19, 2.06%, Pineapple, juice-Uncooked; Fresh or N/S; Cook MethN/S15003251, 240, 227, 2.03%, Rice, flour-babyfood-Cooked; Canned; Cook Meth N/S 8002340, 220, 19, 1.67%, Okra-Cooked; Frozen; Cook Meth N/S10002001, 240, 76, 1.66%, Lemon, juice-babyfood-Cooked; Canned; Cook Meth N/S10003700, 240, 39, 1.33%, Tangerine, juice-Cooked; Canned; Cook Meth N/S10002000, 240, 38, 1.15%, Lemon, juice-Cooked; Canned; Cook Meth N/S13010561, 240, 1, 1.14%, Blackberry, juice-babyfood-Cooked; Canned; CookMeth N/S12000910, 210, 19, 1.05%, Cherry, juice-Cooked; Fresh or N/S; Cook Meth N/S11000100, 110, 54, 1.05%, Apple, juice-Uncooked; Fresh or N/S; Cook Meth N/S11000110, 212, 32, 1.05%, Apple, sauce-Cooked; Fresh or N/S; Boiled13020570, 110, 8, 1.03%, Blueberry-Uncooked; Fresh or N/S; Cook Meth N/S12000141, 240, 11, 1.00%, Apricot, juice-babyfood-Cooked; Canned; Cook MethN/S11000070, 110, 13, 0.99%, Apple, fruit with peel-Uncooked; Fresh or N/S; CookMeth N/S12000121, 240, 38, 0.90%, Apricot-babyfood-Cooked; Canned; Cook Meth N/S13013201, 240, 12, 0.90%, Raspberry-babyfood-Cooked; Canned; Cook Meth N/S10002070, 240, 38, 0.79%, Lime, juice-Cooked; Canned; Cook Meth N/S 1030821, 240, 170, 0.56%, Cassava-babyfood-Cooked; Canned; Cook Meth N/S 6010431, 240, 3, 0.55%, Bean, snap, succulent-babyfood-Cooked; Canned; CookMeth N/S12002600, 110, 7, 0.53%, Peach-Uncooked; Fresh or N/S; Cook Meth N/S13010550, 110, 3, 0.38%, Blackberry-Uncooked; Fresh or N/S; Cook Meth N/S13013200, 240, 8, 0.37%, Raspberry-Cooked; Canned; Cook Meth N/S21000441, 240, 72, 0.36%, Beef, meat-babyfood-Cooked; Canned; Cook Meth N/S13010580, 120, 19, 0.35%, Boysenberry-Uncooked; Frozen; Cook Meth N/S11002660, 240, 4, 0.33%, Pear-Cooked; Canned; Cook Meth N/S11002660, 110, 2, 0.31%, Pear-Uncooked; Fresh or N/S; Cook Meth N/S15001231, 240, 165, 0.28%, Corn, field, starch-babyfood-Cooked; Canned; CookMeth N/S12000901, 240, 9, 0.27%, Cherry-babyfood-Cooked; Canned; Cook Meth N/S95001761, 240, 31, 0.26%, Grape, juice-babyfood-Cooked; Canned; Cook Meth N/S 1033661, 240, 42, 0.25%, Sweet potato-babyfood-Cooked; Canned; Cook Meth N/S10001810, 240, 19, 0.24%, Grapefruit, juice-Cooked; Canned; Cook Meth N/S10002000, 210, 19, 0.24%, Lemon, juice-Cooked; Fresh or N/S; Cook Meth N/S

380

13010580, 240, 20, 0.22%, Boysenberry-Cooked; Canned; Cook Meth N/S27002220, 110, 93, 0.22%, Milk, fat-Uncooked; Fresh or N/S; Cook Meth N/S20003651, 900, 107, 0.20%, Sunflower, oil-babyfood-Refined; FF N/A; Cook MethN/S13013200, 110, 2, 0.20%, Raspberry-Uncooked; Fresh or N/S; Cook Meth N/S 8002720, 212, 25, 0.20%, Pepper, nonbell-Cooked; Fresh or N/S; Boiled10003700, 120, 19, 0.18%, Tangerine, juice-Uncooked; Frozen; Cook Meth N/S12002851, 240, 10, 0.18%, Plum-babyfood-Cooked; Canned; Cook Meth N/S15001241, 240, 76, 0.17%, Corn, field, syrup-babyfood-Cooked; Canned; CookMeth N/S10002000, 120, 19, 0.16%, Lemon, juice-Uncooked; Frozen; Cook Meth N/S25002900, 250, 19, 0.15%, Pork, meat-Cooked; Cured etc; Cook Meth N/S25002930, 250, 21, 0.14%, Pork, fat-Cooked; Cured etc; Cook Meth N/S25002931, 240, 52, 0.14%, Pork, fat-babyfood-Cooked; Canned; Cook Meth N/S10002070, 120, 20, 0.14%, Lime, juice-Uncooked; Frozen; Cook Meth N/S15001241, 230, 63, 0.13%, Corn, field, syrup-babyfood-Cooked; Dried; CookMeth N/S15001210, 233, 62, 0.13%, Corn, field, meal-Cooked; Dried; Fried95000230, 110, 73, 0.13%, Banana-Uncooked; Fresh or N/S; Cook Meth N/S10002410, 110, 6, 0.12%, Orange, juice-Uncooked; Fresh or N/S; Cook Meth N/S12000910, 120, 19, 0.12%, Cherry, juice-Uncooked; Frozen; Cook Meth N/S10002000, 110, 4, 0.11%, Lemon, juice-Uncooked; Fresh or N/S; Cook Meth N/S12002600, 240, 3, 0.11%, Peach-Cooked; Canned; Cook Meth N/S 1033000, 212, 4, 0.11%, Potato, tuber, w/o peel-Cooked; Fresh or N/S;Boiled95001760, 110, 9, 0.10%, Grape, juice-Uncooked; Fresh or N/S; Cook Meth N/S15004020, 211, 67, 0.08%, Wheat, flour-Cooked; Fresh or N/S; Baked21000471, 240, 37, 0.08%, Beef,fat-babyfood-Cooked; Canned; Cook Meth N/S95001750, 110, 3, 0.08%, Grape-Uncooked; Fresh or N/S; Cook Meth N/S12002300, 110, 1, 0.08%, Nectarine-Uncooked; Fresh or N/S; Cook Meth N/S15001231, 130, 26, 0.07%, Corn, field, starch-babyfood-Uncooked; Dried; CookMeth N/S12000910, 240, 19, 0.07%, Cherry, juice-Cooked; Canned; Cook Meth N/S25002901, 240, 29, 0.07%, Pork, meat-babyfood-Cooked; Canned; Cook Meth N/S13013211, 240, 1, 0.06%, Raspberry, juice-babyfood-Cooked; Canned; Cook MethN/S10002410, 240, 19, 0.06%, Orange, juice-Cooked; Canned; Cook Meth N/S10002411, 240, 7, 0.06%, Orange, juice-babyfood-Cooked; Canned; Cook MethN/S12000900, 110, 3, 0.06%, Cherry-Uncooked; Fresh or N/S; Cook Meth N/S 1010790, 240, 19, 0.06%, Carrot, juice-Cooked; Canned; Cook Meth N/S10002071, 240, 19, 0.06%, Lime, juice-babyfood-Cooked; Canned; Cook Meth N/S95002810, 120, 19, 0.06%, Pineapple, juice-Uncooked; Frozen; Cook Meth N/S10001810, 120, 19, 0.05%, Grapefruit, juice-Uncooked; Frozen; Cook Meth N/S10001990, 110, 4, 0.05%, Lemon-Uncooked; Fresh or N/S; Cook Meth N/S15001201, 230, 29, 0.05%, Corn, field, flour-babyfood-Cooked; Dried; CookMeth N/S21000440, 214, 20, 0.05%, Beef, meat-Cooked; Fresh or N/S; Fried/baked 8002711, 240, 3, 0.04%, Pepper, bell, dried-babyfood-Cooked; Canned; CookMeth N/S15001241, 130, 11, 0.04%, Corn, field, syrup-babyfood-Uncooked; Dried; CookMeth N/S 8002700, 213, 1, 0.04%, Pepper, bell-Cooked; Fresh or N/S; Fried95001760, 240, 1, 0.04%, Grape, juice-Cooked; Canned; Cook Meth N/S 9023571, 240, 27, 0.04%, Squash, winter-babyfood-Cooked; Canned; Cook MethN/S 6003481, 230, 41, 0.04%, Soybean, flour-babyfood-Cooked; Dried; Cook MethN/S11002660, 210, 1, 0.03%, Pear-Cooked; Fresh or N/S; Cook Meth N/S15004020, 210, 20, 0.03%, Wheat, flour-Cooked; Fresh or N/S; Cook Meth N/S13010550, 240, 3, 0.03%, Blackberry-Cooked; Canned; Cook Meth N/S95001750, 240, 1, 0.03%, Grape-Cooked; Canned; Cook Meth N/S12002861, 240, 3, 0.03%, Plum, prune, fresh-babyfood-Cooked; Canned; CookMeth N/S15003250, 230, 8, 0.03%, Rice, flour-Cooked; Dried; Cook Meth N/S

381

9013990, 110, 4, 0.03%, Watermelon-Uncooked; Fresh or N/S; Cook Meth N/S13013200, 211, 1, 0.02%, Raspberry-Cooked; Fresh or N/S; Baked15001240, 110, 16, 0.02%, Corn, field, syrup-Uncooked; Fresh or N/S; CookMeth N/S15004020, 212, 19, 0.02%, Wheat, flour-Cooked; Fresh or N/S; Boiled 8002730, 212, 5, 0.02%, Pepper, nonbell, dried-Cooked; Fresh or N/S; Boiled15004010, 211, 12, 0.02%, Wheat, grain-Cooked; Fresh or N/S; Baked 1030820, 240, 19, 0.02%, Cassava-Cooked; Canned; Cook Meth N/S15004020, 232, 13, 0.02%, Wheat, flour-Cooked; Dried; Boiled95002360, 900, 5, 0.02%, Olive, oil-Refined; FF N/A; Cook Meth N/S25002900, 240, 3, 0.02%, Pork, meat-Cooked; Canned; Cook Meth N/S27002220, 212, 19, 0.01%, Milk, fat-Cooked; Fresh or N/S; Boiled12000900, 240, 1, 0.01%, Cherry-Cooked; Canned; Cook Meth N/S 8002730, 210, 2, 0.01%, Pepper, nonbell, dried-Cooked; Fresh or N/S; CookMeth N/S25002930, 253, 2, 0.01%, Pork, fat-Cooked; Cured etc; Fried25002930, 240, 3, 0.01%, Pork, fat-Cooked; Canned; Cook Meth N/S95002790, 110, 4, 0.01%, Pineapple-Uncooked; Fresh or N/S; Cook Meth N/S15001240, 211, 9, 0.01%, Corn, field, syrup-Cooked; Fresh or N/S; Baked 1010790, 110, 1, 0.01%, Carrot, juice-Uncooked; Fresh or N/S; Cook Meth N/S10002410, 120, 5, 0.01%, Orange, juice-Uncooked; Frozen; Cook Meth N/S15004021, 240, 19, 0.01%, Wheat, flour-babyfood-Cooked; Canned; Cook Meth N/S 8003790, 212, 1, 0.01%, Tomato, juice-Cooked; Fresh or N/S; Boiled 8003770, 212, 5, 0.01%, Tomato, puree-Cooked; Fresh or N/S; Boiled27002220, 232, 3, 0.01%, Milk, fat-Cooked; Dried; Boiled25002930, 212, 2, 0.01%, Pork, fat-Cooked; Fresh or N/S; Boiled 1010781, 240, 7, 0.01%, Carrot-babyfood-Cooked; Canned; Cook Meth N/S15001240, 240, 6, 0.01%, Corn, field, syrup-Cooked; Canned; Cook Meth N/S 8003750, 212, 2, 0.01%, Tomato-Cooked; Fresh or N/S; Boiled13013210, 120, 2, 0.01%, Raspberry, juice-Uncooked; Frozen; Cook Meth N/S 8003761, 240, 8, 0.01%, Tomato, paste-babyfood-Cooked; Canned; Cook MethN/S15004011, 230, 11, 0.01%, Wheat, grain-babyfood-Cooked; Dried; Cook Meth N/S27022240, 110, 8, 0.01%, Milk, water-Uncooked; Fresh or N/S; Cook Meth N/S 8003770, 210, 4, 0.01%, Tomato, puree-Cooked; Fresh or N/S; Cook Meth N/S13020570, 240, 2, 0.01%, Blueberry-Cooked; Canned; Cook Meth N/S11000090, 230, 2, 0.01%, Apple, dried-Cooked; Dried; Cook Meth N/S95003601, 240, 1, 0.01%, Strawberry, juice-babyfood-Cooked; Canned; CookMeth N/S15001200, 230, 3, 0.01%, Corn, field, flour-Cooked; Dried; Cook Meth N/S95002640, 210, 6, 0.01%, Peanut, butter-Cooked; Fresh or N/S; Cook Meth N/S11000080, 211, 1, 0.00%, Apple, peeled fruit-Cooked; Fresh or N/S; Baked21000470, 210, 3, 0.00%, Beef, fat-Cooked; Fresh or N/S; Cook Meth N/S95001750, 210, 1, 0.00%, Grape-Cooked; Fresh or N/S; Cook Meth N/S 8002730, 240, 1, 0.00%, Pepper, nonbell, dried-Cooked; Canned; Cook MethN/S 1030820, 231, 1, 0.00%, Cassava-Cooked; Dried; Baked10002000, 130, 1, 0.00%, Lemon, juice-Uncooked; Dried; Cook Meth N/S27002220, 120, 4, 0.00%, Milk, fat-Uncooked; Frozen; Cook Meth N/S21000470, 212, 1, 0.00%, Beef, fat-Cooked; Fresh or N/S; Boiled27002220, 211, 4, 0.00%, Milk, fat-Cooked; Fresh or N/S; Baked21000440, 210, 3, 0.00%, Beef, meat-Cooked; Fresh or N/S; Cook Meth N/S 4012480, 212, 2, 0.00%, Parsley, leaves-Cooked; Fresh or N/S; Boiled95003590, 211, 1, 0.00%, Strawberry-Cooked; Fresh or N/S; Baked21000440, 212, 1, 0.00%, Beef, meat-Cooked; Fresh or N/S; Boiled 6003470, 212, 2, 0.00%, Soybean, seed-Cooked; Fresh or N/S; Boiled 8003760, 210, 2, 0.00%, Tomato, paste-Cooked; Fresh or N/S; Cook Meth N/S 8002730, 232, 2, 0.00%, Pepper, nonbell, dried-Cooked; Dried; Boiled 1010780, 212, 1, 0.00%, Carrot-Cooked; Fresh or N/S; Boiled13020570, 120, 1, 0.00%, Blueberry-Uncooked; Frozen; Cook Meth N/S15001240, 212, 2, 0.00%, Corn, field, syrup-Cooked; Fresh or N/S; Boiled 4012480, 210, 1, 0.00%, Parsley, leaves-Cooked; Fresh or N/S; Cook Meth N/S11000100, 120, 1, 0.00%, Apple, juice-Uncooked; Frozen; Cook Meth N/S 9011870, 110, 1, 0.00%, Honeydew melon-Uncooked; Fresh or N/S; Cook MethN/S

382

13020570, 211, 1, 0.00%, Blueberry-Cooked; Fresh or N/S; Baked95001760, 120, 1, 0.00%, Grape, juice-Uncooked; Frozen; Cook Meth N/S12002600, 211, 2, 0.00%, Peach-Cooked; Fresh or N/S; Baked15004010, 232, 1, 0.00%, Wheat, grain-Cooked; Dried; Boiled15003241, 230, 1, 0.00%, Rice, brown-babyfood-Cooked; Dried; Cook Meth N/S15004010, 230, 1, 0.00%, Wheat, grain-Cooked; Dried; Cook Meth N/S11000100, 240, 1, 0.00%, Apple, juice-Cooked; Canned; Cook Meth N/S 1032981, 240, 1, 0.00%, Potato, flour-babyfood-Cooked; Canned; Cook MethN/S95001760, 210, 1, 0.00%, Grape, juice-Cooked; Fresh or N/S; Cook Meth N/S95003590, 110, 1, 0.00%, Strawberry-Uncooked; Fresh or N/S; Cook Meth N/S15003240, 210, 1, 0.00%, Rice, brown-Cooked; Fresh or N/S; Cook Meth N/S15003241, 240, 1, 0.00%, Rice, brown-babyfood-Cooked; Canned; Cook Meth N/S15004020, 231, 1, 0.00%, Wheat, flour-Cooked; Dried; Baked15004020, 230, 1, 0.00%, Wheat, flour-Cooked; Dried; Cook Meth N/S 6010430, 242, 1, 0.00%, Bean, snap, succulent-Cooked; Canned; Boiled15001231, 110, 1, 0.00%, Corn, field, starch-babyfood-Uncooked; Fresh orN/S; Cook Meth N/S

383

Non-nursing infants (<1 yr old)Low percentile for CEC records: 95 Exposure (mg/day) = 0.000771High percentile for CEC records: 100 Exposure (mg/day) = 0.157992Number of actual records in this interval: 1842

Critical foods/foodforms for this population (as derived from these records): N=number of appearances in all records (including duplicates) %=percent of total exposure for all records (including duplicates)

Food, FF, N , Percent, Food Name --------, ---, -----, -------, -------------12000911, 240, 557, 13.84%, Cherry, juice-babyfood-Cooked; Canned; Cook MethN/S12002881, 240, 323, 13.35%, Plum, prune, juice-babyfood-Cooked; Canned; CookMeth N/S12002880, 110, 76, 12.06%, Plum, prune, juice-Uncooked; Fresh or N/S; CookMeth N/S12000910, 110, 19, 6.36%, Cherry, juice-Uncooked; Fresh or N/S; Cook Meth N/S12002601, 240, 135, 5.30%, Peach-babyfood-Cooked; Canned; Cook Meth N/S13020571, 240, 48, 4.51%, Blueberry-babyfood-Cooked; Canned; Cook Meth N/S12002621, 240, 171, 4.34%, Peach, juice-babyfood-Cooked; Canned; Cook Meth N/S95002810, 110, 96, 3.00%, Pineapple, juice-Uncooked; Fresh or N/S; Cook MethN/S15003251, 230, 672, 2.97%, Rice, flour-babyfood-Cooked; Dried; Cook Meth N/S10001810, 240, 40, 2.86%, Grapefruit, juice-Cooked; Canned; Cook Meth N/S11002661, 240, 55, 2.52%, Pear-babyfood-Cooked; Canned; Cook Meth N/S10001810, 110, 20, 2.46%, Grapefruit, juice-Uncooked; Fresh or N/S; Cook MethN/S95002811, 240, 309, 1.60%, Pineapple, juice-babyfood-Cooked; Canned; Cook MethN/S95002810, 240, 87, 1.55%, Pineapple, juice-Cooked; Canned; Cook Meth N/S11000111, 240, 243, 1.53%, Apple, sauce-babyfood-Cooked; Canned; Cook Meth N/S11000101, 240, 623, 1.45%, Apple, juice-babyfood-Cooked; Canned; Cook Meth N/S12000910, 210, 39, 1.41%, Cherry, juice-Cooked; Fresh or N/S; Cook Meth N/S 8002340, 220, 19, 1.18%, Okra-Cooked; Frozen; Cook Meth N/S11000081, 240, 53, 1.15%, Apple, peeled fruit-babyfood-Cooked; Canned; CookMeth N/S12000121, 240, 63, 0.95%, Apricot-babyfood-Cooked; Canned; Cook Meth N/S11000091, 230, 68, 0.88%, Apple, dried-babyfood-Cooked; Dried; Cook Meth N/S 8002340, 210, 19, 0.87%, Okra-Cooked; Fresh or N/S; Cook Meth N/S10003700, 110, 19, 0.86%, Tangerine, juice-Uncooked; Fresh or N/S; Cook MethN/S10003690, 110, 19, 0.75%, Tangerine-Uncooked; Fresh or N/S; Cook Meth N/S12000141, 240, 56, 0.70%, Apricot, juice-babyfood-Cooked; Canned; Cook MethN/S15003251, 240, 341, 0.69%, Rice, flour-babyfood-Cooked; Canned; Cook Meth N/S13013201, 240, 30, 0.66%, Raspberry-babyfood-Cooked; Canned; Cook Meth N/S11000070, 110, 9, 0.63%, Apple, fruit with peel-Uncooked; Fresh or N/S; CookMeth N/S11000100, 110, 133, 0.61%, Apple, juice-Uncooked; Fresh or N/S; Cook Meth N/S95001760, 240, 85, 0.46%, Grape, juice-Cooked; Canned; Cook Meth N/S10002001, 240, 124, 0.44%, Lemon, juice-babyfood-Cooked; Canned; Cook Meth N/S12000901, 240, 23, 0.36%, Cherry-babyfood-Cooked; Canned; Cook Meth N/S95001750, 110, 10, 0.35%, Grape-Uncooked; Fresh or N/S; Cook Meth N/S11000110, 212, 54, 0.33%, Apple, sauce-Cooked; Fresh or N/S; Boiled10002000, 210, 39, 0.32%, Lemon, juice-Cooked; Fresh or N/S; Cook Meth N/S 6010431, 240, 9, 0.31%, Bean, snap, succulent-babyfood-Cooked; Canned; CookMeth N/S11000100, 240, 80, 0.30%, Apple, juice-Cooked; Canned; Cook Meth N/S12002600, 110, 11, 0.29%, Peach-Uncooked; Fresh or N/S; Cook Meth N/S95001761, 240, 47, 0.29%, Grape, juice-babyfood-Cooked; Canned; Cook Meth N/S11002681, 240, 10, 0.27%, Pear, juice-babyfood-Cooked; Canned; Cook Meth N/S13020570, 110, 6, 0.23%, Blueberry-Uncooked; Fresh or N/S; Cook Meth N/S10002000, 110, 19, 0.16%, Lemon, juice-Uncooked; Fresh or N/S; Cook Meth N/S

384

4013551, 240, 11, 0.14%, Spinach-babyfood-Cooked; Canned; Cook Meth N/S13013211, 240, 5, 0.14%, Raspberry, juice-babyfood-Cooked; Canned; Cook MethN/S20003651, 900, 268, 0.13%, Sunflower, oil-babyfood-Refined; FF N/A; Cook MethN/S27002220, 110, 195, 0.13%, Milk, fat-Uncooked; Fresh or N/S; Cook Meth N/S25002930, 210, 65, 0.12%, Pork, fat-Cooked; Fresh or N/S; Cook Meth N/S12000900, 110, 3, 0.12%, Cherry-Uncooked; Fresh or N/S; Cook Meth N/S15001241, 240, 116, 0.11%, Corn, field, syrup-babyfood-Cooked; Canned; CookMeth N/S10003700, 240, 21, 0.11%, Tangerine, juice-Cooked; Canned; Cook Meth N/S15001241, 230, 105, 0.10%, Corn, field, syrup-babyfood-Cooked; Dried; CookMeth N/S10002000, 240, 21, 0.09%, Lemon, juice-Cooked; Canned; Cook Meth N/S10002070, 240, 21, 0.09%, Lime, juice-Cooked; Canned; Cook Meth N/S15001241, 130, 76, 0.09%, Corn, field, syrup-babyfood-Uncooked; Dried; CookMeth N/S 1033661, 240, 72, 0.08%, Sweet potato-babyfood-Cooked; Canned; Cook Meth N/S25002931, 240, 78, 0.08%, Pork, fat-babyfood-Cooked; Canned; Cook Meth N/S11002660, 110, 1, 0.07%, Pear-Uncooked; Fresh or N/S; Cook Meth N/S 1030821, 240, 132, 0.07%, Cassava-babyfood-Cooked; Canned; Cook Meth N/S95001760, 110, 9, 0.07%, Grape, juice-Uncooked; Fresh or N/S; Cook Meth N/S13010561, 240, 3, 0.07%, Blackberry, juice-babyfood-Cooked; Canned; CookMeth N/S11000080, 211, 3, 0.07%, Apple, peeled fruit-Cooked; Fresh or N/S; Baked11000090, 211, 39, 0.07%, Apple, dried-Cooked; Fresh or N/S; Baked15001231, 240, 118, 0.06%, Corn, field, starch-babyfood-Cooked; Canned; CookMeth N/S12002600, 240, 1, 0.06%, Peach-Cooked; Canned; Cook Meth N/S25002930, 213, 63, 0.05%, Pork, fat-Cooked; Fresh or N/S; Fried11000110, 210, 5, 0.05%, Apple, sauce-Cooked; Fresh or N/S; Cook Meth N/S25002930, 240, 21, 0.05%, Pork, fat-Cooked; Canned; Cook Meth N/S25002901, 240, 71, 0.04%, Pork, meat-babyfood-Cooked; Canned; Cook Meth N/S11002680, 240, 1, 0.04%, Pear, juice-Cooked; Canned; Cook Meth N/S10002410, 110, 61, 0.04%, Orange, juice-Uncooked; Fresh or N/S; Cook Meth N/S10002410, 240, 48, 0.04%, Orange, juice-Cooked; Canned; Cook Meth N/S11002660, 210, 2, 0.04%, Pear-Cooked; Fresh or N/S; Cook Meth N/S11002660, 240, 2, 0.04%, Pear-Cooked; Canned; Cook Meth N/S12002851, 240, 8, 0.04%, Plum-babyfood-Cooked; Canned; Cook Meth N/S13010550, 240, 1, 0.03%, Blackberry-Cooked; Canned; Cook Meth N/S15001231, 130, 55, 0.03%, Corn, field, starch-babyfood-Uncooked; Dried; CookMeth N/S21000441, 240, 87, 0.03%, Beef, meat-babyfood-Cooked; Canned; Cook Meth N/S15003240, 210, 14, 0.03%, Rice, brown-Cooked; Fresh or N/S; Cook Meth N/S12002861, 240, 5, 0.03%, Plum, prune, fresh-babyfood-Cooked; Canned; CookMeth N/S 9010750, 110, 2, 0.03%, Cantaloupe-Uncooked; Fresh or N/S; Cook Meth N/S12002600, 210, 2, 0.03%, Peach-Cooked; Fresh or N/S; Cook Meth N/S95003600, 240, 1, 0.03%, Strawberry, juice-Cooked; Canned; Cook Meth N/S25002930, 232, 20, 0.02%, Pork, fat-Cooked; Dried; Boiled95002350, 211, 1, 0.02%, Olive-Cooked; Fresh or N/S; Baked25002930, 250, 22, 0.02%, Pork, fat-Cooked; Cured etc; Cook Meth N/S 8002730, 240, 21, 0.02%, Pepper, nonbell, dried-Cooked; Canned; Cook MethN/S21000470, 210, 31, 0.02%, Beef, fat-Cooked; Fresh or N/S; Cook Meth N/S 9023080, 211, 19, 0.02%, Pumpkin-Cooked; Fresh or N/S; Baked95001750, 210, 2, 0.02%, Grape-Cooked; Fresh or N/S; Cook Meth N/S95001760, 120, 1, 0.02%, Grape, juice-Uncooked; Frozen; Cook Meth N/S 8003770, 240, 40, 0.02%, Tomato, puree-Cooked; Canned; Cook Meth N/S25002930, 212, 21, 0.01%, Pork, fat-Cooked; Fresh or N/S; Boiled25002900, 250, 22, 0.01%, Pork, meat-Cooked; Cured etc; Cook Meth N/S15001210, 230, 22, 0.01%, Corn, field, meal-Cooked; Dried; Cook Meth N/S 6010430, 242, 1, 0.01%, Bean, snap, succulent-Cooked; Canned; Boiled27002220, 230, 20, 0.01%, Milk, fat-Cooked; Dried; Cook Meth N/S15004020, 211, 33, 0.01%, Wheat, flour-Cooked; Fresh or N/S; Baked

385

10002411, 240, 20, 0.01%, Orange, juice-babyfood-Cooked; Canned; Cook MethN/S13013200, 110, 1, 0.01%, Raspberry-Uncooked; Fresh or N/S; Cook Meth N/S95000230, 110, 34, 0.01%, Banana-Uncooked; Fresh or N/S; Cook Meth N/S 6032560, 232, 18, 0.01%, Pea, dry-Cooked; Dried; Boiled15004011, 230, 19, 0.01%, Wheat, grain-babyfood-Cooked; Dried; Cook Meth N/S15001240, 240, 22, 0.01%, Corn, field, syrup-Cooked; Canned; Cook Meth N/S 1033000, 212, 5, 0.01%, Potato, tuber, w/o peel-Cooked; Fresh or N/S;Boiled15004020, 231, 19, 0.01%, Wheat, flour-Cooked; Dried; Baked10002410, 120, 4, 0.01%, Orange, juice-Uncooked; Frozen; Cook Meth N/S21000440, 213, 19, 0.01%, Beef, meat-Cooked; Fresh or N/S; Fried10002071, 240, 18, 0.01%, Lime, juice-babyfood-Cooked; Canned; Cook Meth N/S 8002720, 210, 1, 0.01%, Pepper, nonbell-Cooked; Fresh or N/S; Cook Meth N/S21000470, 213, 19, 0.01%, Beef, fat-Cooked; Fresh or N/S; Fried12002850, 110, 2, 0.01%, Plum-Uncooked; Fresh or N/S; Cook Meth N/S25002900, 240, 19, 0.01%, Pork, meat-Cooked; Canned; Cook Meth N/S15001200, 230, 16, 0.01%, Corn, field, flour-Cooked; Dried; Cook Meth N/S15004020, 232, 8, 0.01%, Wheat, flour-Cooked; Dried; Boiled21000440, 211, 6, 0.01%, Beef, meat-Cooked; Fresh or N/S; Baked 1033000, 211, 2, 0.01%, Potato, tuber, w/o peel-Cooked; Fresh or N/S; Baked13010580, 240, 2, 0.01%, Boysenberry-Cooked; Canned; Cook Meth N/S13013200, 240, 1, 0.00%, Raspberry-Cooked; Canned; Cook Meth N/S 8002700, 211, 1, 0.00%, Pepper, bell-Cooked; Fresh or N/S; Baked27002220, 232, 3, 0.00%, Milk, fat-Cooked; Dried; Boiled15001240, 110, 8, 0.00%, Corn, field, syrup-Uncooked; Fresh or N/S; CookMeth N/S 8003770, 210, 4, 0.00%, Tomato, puree-Cooked; Fresh or N/S; Cook Meth N/S25002930, 253, 2, 0.00%, Pork, fat-Cooked; Cured etc; Fried 8002730, 212, 5, 0.00%, Pepper, nonbell, dried-Cooked; Fresh or N/S; Boiled21000470, 211, 4, 0.00%, Beef, fat-Cooked; Fresh or N/S; Baked10002000, 211, 4, 0.00%, Lemon, juice-Cooked; Fresh or N/S; Baked 8002720, 212, 2, 0.00%, Pepper, nonbell-Cooked; Fresh or N/S; Boiled 8002730, 210, 1, 0.00%, Pepper, nonbell, dried-Cooked; Fresh or N/S; CookMeth N/S 1010781, 240, 8, 0.00%, Carrot-babyfood-Cooked; Canned; Cook Meth N/S 6003481, 240, 10, 0.00%, Soybean, flour-babyfood-Cooked; Canned; Cook MethN/S27002220, 211, 5, 0.00%, Milk, fat-Cooked; Fresh or N/S; Baked26003391, 240, 5, 0.00%, Sheep, meat-babyfood-Cooked; Canned; Cook Meth N/S 8003770, 212, 3, 0.00%, Tomato, puree-Cooked; Fresh or N/S; Boiled 8002700, 215, 2, 0.00%, Pepper, bell-Cooked; Fresh or N/S; Boiled/baked 1010501, 240, 2, 0.00%, Beet, garden, roots-babyfood-Cooked; Canned; CookMeth N/S 9023571, 240, 4, 0.00%, Squash, winter-babyfood-Cooked; Canned; Cook MethN/S 9013990, 110, 2, 0.00%, Watermelon-Uncooked; Fresh or N/S; Cook Meth N/S12000910, 240, 2, 0.00%, Cherry, juice-Cooked; Canned; Cook Meth N/S 8003790, 212, 1, 0.00%, Tomato, juice-Cooked; Fresh or N/S; Boiled11000100, 210, 2, 0.00%, Apple, juice-Cooked; Fresh or N/S; Cook Meth N/S15001201, 230, 4, 0.00%, Corn, field, flour-babyfood-Cooked; Dried; CookMeth N/S25002900, 213, 1, 0.00%, Pork, meat-Cooked; Fresh or N/S; Fried10001800, 110, 2, 0.00%, Grapefruit-Uncooked; Fresh or N/S; Cook Meth N/S 8002720, 240, 2, 0.00%, Pepper, nonbell-Cooked; Canned; Cook Meth N/S95002791, 240, 1, 0.00%, Pineapple-babyfood-Cooked; Canned; Cook Meth N/S15001240, 130, 2, 0.00%, Corn, field, syrup-Uncooked; Dried; Cook Meth N/S95001760, 210, 1, 0.00%, Grape, juice-Cooked; Fresh or N/S; Cook Meth N/S 9023560, 212, 2, 0.00%, Squash, summer-Cooked; Fresh or N/S; Boiled21000440, 210, 2, 0.00%, Beef, meat-Cooked; Fresh or N/S; Cook Meth N/S27002220, 213, 2, 0.00%, Milk, fat-Cooked; Fresh or N/S; Fried95002360, 900, 2, 0.00%, Olive, oil-Refined; FF N/A; Cook Meth N/S 1010780, 212, 2, 0.00%, Carrot-Cooked; Fresh or N/S; Boiled 9011870, 110, 1, 0.00%, Honeydew melon-Uncooked; Fresh or N/S; Cook MethN/S

386

8003760, 210, 1, 0.00%, Tomato, paste-Cooked; Fresh or N/S; Cook Meth N/S 1033660, 211, 1, 0.00%, Sweet potato-Cooked; Fresh or N/S; Baked 8002730, 232, 2, 0.00%, Pepper, nonbell, dried-Cooked; Dried; Boiled 5010830, 212, 1, 0.00%, Cauliflower-Cooked; Fresh or N/S; Boiled15003250, 230, 1, 0.00%, Rice, flour-Cooked; Dried; Cook Meth N/S 4012480, 210, 1, 0.00%, Parsley, leaves-Cooked; Fresh or N/S; Cook Meth N/S 1032981, 240, 1, 0.00%, Potato, flour-babyfood-Cooked; Canned; Cook MethN/S21000440, 212, 1, 0.00%, Beef, meat-Cooked; Fresh or N/S; Boiled21000471, 240, 2, 0.00%, Beef,fat-babyfood-Cooked; Canned; Cook Meth N/S27002220, 215, 1, 0.00%, Milk, fat-Cooked; Fresh or N/S; Boiled/baked25002900, 210, 1, 0.00%, Pork, meat-Cooked; Fresh or N/S; Cook Meth N/S95002640, 210, 1, 0.00%, Peanut, butter-Cooked; Fresh or N/S; Cook Meth N/S13010580, 120, 2, 0.00%, Boysenberry-Uncooked; Frozen; Cook Meth N/S27002220, 210, 1, 0.00%, Milk, fat-Cooked; Fresh or N/S; Cook Meth N/S 1033001, 240, 1, 0.00%, Potato, tuber, w/o peel-babyfood-Cooked; Canned;Cook Meth N/S15004020, 215, 1, 0.00%, Wheat, flour-Cooked; Fresh or N/S; Boiled/baked15001240, 212, 1, 0.00%, Corn, field, syrup-Cooked; Fresh or N/S; Boiled15004020, 212, 1, 0.00%, Wheat, flour-Cooked; Fresh or N/S; Boiled95002790, 110, 1, 0.00%, Pineapple-Uncooked; Fresh or N/S; Cook Meth N/S15003241, 240, 1, 0.00%, Rice, brown-babyfood-Cooked; Canned; Cook Meth N/S21000470, 212, 1, 0.00%, Beef, fat-Cooked; Fresh or N/S; Boiled15001241, 110, 1, 0.00%, Corn, field, syrup-babyfood-Uncooked; Fresh or N/S;Cook Meth N/S15004020, 230, 1, 0.00%, Wheat, flour-Cooked; Dried; Cook Meth N/S27022240, 110, 1, 0.00%, Milk, water-Uncooked; Fresh or N/S; Cook Meth N/S25002900, 212, 1, 0.00%, Pork, meat-Cooked; Fresh or N/S; Boiled

387

Females 13+ (preg/not nursing)Low percentile for CEC records: 95 Exposure (mg/day) = 0.000373High percentile for CEC records: 100 Exposure (mg/day) = 0.010069Number of actual records in this interval: 131

Critical foods/foodforms for this population (as derived from these records): N=number of appearances in all records (including duplicates) %=percent of total exposure for all records (including duplicates)

Food, FF, N , Percent, Food Name --------, ---, -----, -------, ------------- 8002720, 212, 38, 39.56%, Pepper, nonbell-Cooked; Fresh or N/S; Boiled13020570, 110, 3, 11.08%, Blueberry-Uncooked; Fresh or N/S; Cook Meth N/S 8002720, 110, 19, 8.57%, Pepper, nonbell-Uncooked; Fresh or N/S; Cook MethN/S 8002720, 213, 19, 8.23%, Pepper, nonbell-Cooked; Fresh or N/S; Fried10002000, 110, 23, 6.72%, Lemon, juice-Uncooked; Fresh or N/S; Cook Meth N/S95002810, 110, 20, 5.90%, Pineapple, juice-Uncooked; Fresh or N/S; Cook MethN/S10001990, 110, 19, 3.56%, Lemon-Uncooked; Fresh or N/S; Cook Meth N/S11000070, 110, 4, 3.00%, Apple, fruit with peel-Uncooked; Fresh or N/S; CookMeth N/S12002300, 110, 1, 1.35%, Nectarine-Uncooked; Fresh or N/S; Cook Meth N/S13010550, 240, 2, 0.96%, Blackberry-Cooked; Canned; Cook Meth N/S10003700, 240, 20, 0.77%, Tangerine, juice-Cooked; Canned; Cook Meth N/S11002660, 110, 1, 0.74%, Pear-Uncooked; Fresh or N/S; Cook Meth N/S12002600, 211, 1, 0.69%, Peach-Cooked; Fresh or N/S; Baked10002000, 240, 20, 0.67%, Lemon, juice-Cooked; Canned; Cook Meth N/S 8002720, 240, 20, 0.62%, Pepper, nonbell-Cooked; Canned; Cook Meth N/S95003600, 110, 1, 0.57%, Strawberry, juice-Uncooked; Fresh or N/S; Cook MethN/S95001750, 110, 1, 0.46%, Grape-Uncooked; Fresh or N/S; Cook Meth N/S10002070, 240, 20, 0.45%, Lime, juice-Cooked; Canned; Cook Meth N/S12000910, 240, 1, 0.31%, Cherry, juice-Cooked; Canned; Cook Meth N/S25002930, 230, 20, 0.27%, Pork, fat-Cooked; Dried; Cook Meth N/S25002930, 232, 19, 0.27%, Pork, fat-Cooked; Dried; Boiled15001200, 214, 39, 0.25%, Corn, field, flour-Cooked; Fresh or N/S;Fried/baked12002600, 110, 2, 0.24%, Peach-Uncooked; Fresh or N/S; Cook Meth N/S10002000, 211, 19, 0.22%, Lemon, juice-Cooked; Fresh or N/S; Baked21000440, 210, 38, 0.18%, Beef, meat-Cooked; Fresh or N/S; Cook Meth N/S10001810, 240, 20, 0.15%, Grapefruit, juice-Cooked; Canned; Cook Meth N/S15004020, 211, 20, 0.15%, Wheat, flour-Cooked; Fresh or N/S; Baked 8002720, 210, 20, 0.13%, Pepper, nonbell-Cooked; Fresh or N/S; Cook Meth N/S 8002730, 210, 20, 0.13%, Pepper, nonbell, dried-Cooked; Fresh or N/S; CookMeth N/S 8002700, 213, 2, 0.12%, Pepper, bell-Cooked; Fresh or N/S; Fried 8002700, 210, 4, 0.12%, Pepper, bell-Cooked; Fresh or N/S; Cook Meth N/S15001240, 110, 19, 0.11%, Corn, field, syrup-Uncooked; Fresh or N/S; CookMeth N/S15004020, 210, 19, 0.10%, Wheat, flour-Cooked; Fresh or N/S; Cook Meth N/S 8002700, 215, 1, 0.09%, Pepper, bell-Cooked; Fresh or N/S; Boiled/baked12002850, 110, 2, 0.09%, Plum-Uncooked; Fresh or N/S; Cook Meth N/S15001240, 240, 20, 0.09%, Corn, field, syrup-Cooked; Canned; Cook Meth N/S10002000, 210, 1, 0.06%, Lemon, juice-Cooked; Fresh or N/S; Cook Meth N/S10002000, 130, 1, 0.06%, Lemon, juice-Uncooked; Dried; Cook Meth N/S10002410, 110, 5, 0.06%, Orange, juice-Uncooked; Fresh or N/S; Cook Meth N/S 8002730, 212, 2, 0.05%, Pepper, nonbell, dried-Cooked; Fresh or N/S; Boiled 8002720, 211, 1, 0.05%, Pepper, nonbell-Cooked; Fresh or N/S; Baked95001760, 110, 1, 0.03%, Grape, juice-Uncooked; Fresh or N/S; Cook Meth N/S15003250, 230, 1, 0.03%, Rice, flour-Cooked; Dried; Cook Meth N/S11000100, 110, 1, 0.02%, Apple, juice-Uncooked; Fresh or N/S; Cook Meth N/S10001810, 110, 1, 0.02%, Grapefruit, juice-Uncooked; Fresh or N/S; Cook MethN/S

388

8002720, 215, 2, 0.02%, Pepper, nonbell-Cooked; Fresh or N/S; Boiled/baked27002220, 120, 2, 0.02%, Milk, fat-Uncooked; Frozen; Cook Meth N/S21000440, 211, 1, 0.01%, Beef, meat-Cooked; Fresh or N/S; Baked 8002730, 240, 1, 0.01%, Pepper, nonbell, dried-Cooked; Canned; Cook MethN/S27002220, 211, 1, 0.01%, Milk, fat-Cooked; Fresh or N/S; Baked15001200, 211, 1, 0.01%, Corn, field, flour-Cooked; Fresh or N/S; Baked25002930, 250, 1, 0.01%, Pork, fat-Cooked; Cured etc; Cook Meth N/S12000140, 240, 1, 0.01%, Apricot, juice-Cooked; Canned; Cook Meth N/S 6030410, 232, 1, 0.00%, Bean, pink, seed-Cooked; Dried; Boiled15004020, 212, 1, 0.00%, Wheat, flour-Cooked; Fresh or N/S; Boiled21000440, 213, 1, 0.00%, Beef, meat-Cooked; Fresh or N/S; Fried27002220, 110, 1, 0.00%, Milk, fat-Uncooked; Fresh or N/S; Cook Meth N/S

389

Females 13+ (nursing)Low percentile for CEC records: 95 Exposure (mg/day) = 0.000334High percentile for CEC records: 100 Exposure (mg/day) = 0.004275Number of actual records in this interval: 98

Critical foods/foodforms for this population (as derived from these records): N=number of appearances in all records (including duplicates) %=percent of total exposure for all records (including duplicates)

Food, FF, N , Percent, Food Name --------, ---, -----, -------, -------------95002810, 110, 23, 21.99%, Pineapple, juice-Uncooked; Fresh or N/S; Cook MethN/S12002620, 240, 19, 18.53%, Peach, juice-Cooked; Canned; Cook Meth N/S10001810, 110, 19, 15.74%, Grapefruit, juice-Uncooked; Fresh or N/S; Cook MethN/S10002000, 110, 24, 11.42%, Lemon, juice-Uncooked; Fresh or N/S; Cook Meth N/S13020570, 214, 1, 4.53%, Blueberry-Cooked; Fresh or N/S; Fried/baked12002600, 110, 3, 3.45%, Peach-Uncooked; Fresh or N/S; Cook Meth N/S11000070, 110, 2, 3.11%, Apple, fruit with peel-Uncooked; Fresh or N/S; CookMeth N/S95001750, 110, 3, 2.75%, Grape-Uncooked; Fresh or N/S; Cook Meth N/S12000900, 211, 2, 2.26%, Cherry-Cooked; Fresh or N/S; Baked12000900, 110, 1, 1.98%, Cherry-Uncooked; Fresh or N/S; Cook Meth N/S 8002700, 110, 2, 1.48%, Pepper, bell-Uncooked; Fresh or N/S; Cook Meth N/S13020570, 110, 4, 1.04%, Blueberry-Uncooked; Fresh or N/S; Cook Meth N/S12000120, 110, 2, 0.84%, Apricot-Uncooked; Fresh or N/S; Cook Meth N/S11000100, 110, 4, 0.76%, Apple, juice-Uncooked; Fresh or N/S; Cook Meth N/S13013210, 240, 1, 0.57%, Raspberry, juice-Cooked; Canned; Cook Meth N/S95003600, 240, 1, 0.56%, Strawberry, juice-Cooked; Canned; Cook Meth N/S13010550, 240, 3, 0.47%, Blackberry-Cooked; Canned; Cook Meth N/S 6010430, 242, 1, 0.39%, Bean, snap, succulent-Cooked; Canned; Boiled10002400, 110, 2, 0.39%, Orange-Uncooked; Fresh or N/S; Cook Meth N/S25002930, 210, 37, 0.38%, Pork, fat-Cooked; Fresh or N/S; Cook Meth N/S 8002720, 210, 2, 0.37%, Pepper, nonbell-Cooked; Fresh or N/S; Cook Meth N/S 8002730, 212, 4, 0.33%, Pepper, nonbell, dried-Cooked; Fresh or N/S; Boiled13013200, 240, 2, 0.31%, Raspberry-Cooked; Canned; Cook Meth N/S21000470, 210, 19, 0.25%, Beef, fat-Cooked; Fresh or N/S; Cook Meth N/S 8002720, 110, 18, 0.23%, Pepper, nonbell-Uncooked; Fresh or N/S; Cook MethN/S13013200, 110, 4, 0.21%, Raspberry-Uncooked; Fresh or N/S; Cook Meth N/S15001240, 240, 20, 0.19%, Corn, field, syrup-Cooked; Canned; Cook Meth N/S21000440, 210, 18, 0.17%, Beef, meat-Cooked; Fresh or N/S; Cook Meth N/S15004020, 232, 18, 0.16%, Wheat, flour-Cooked; Dried; Boiled10002070, 110, 4, 0.15%, Lime, juice-Uncooked; Fresh or N/S; Cook Meth N/S15001240, 110, 17, 0.15%, Corn, field, syrup-Uncooked; Fresh or N/S; CookMeth N/S95001750, 240, 2, 0.12%, Grape-Cooked; Canned; Cook Meth N/S10002410, 110, 4, 0.12%, Orange, juice-Uncooked; Fresh or N/S; Cook Meth N/S 8003770, 210, 15, 0.10%, Tomato, puree-Cooked; Fresh or N/S; Cook Meth N/S10002000, 211, 2, 0.09%, Lemon, juice-Cooked; Fresh or N/S; Baked 9023080, 211, 4, 0.08%, Pumpkin-Cooked; Fresh or N/S; Baked27002220, 110, 5, 0.07%, Milk, fat-Uncooked; Fresh or N/S; Cook Meth N/S15004020, 211, 4, 0.06%, Wheat, flour-Cooked; Fresh or N/S; Baked10001990, 110, 1, 0.05%, Lemon-Uncooked; Fresh or N/S; Cook Meth N/S 9021350, 110, 2, 0.05%, Cucumber-Uncooked; Fresh or N/S; Cook Meth N/S 8003740, 210, 2, 0.03%, Tomatillo-Cooked; Fresh or N/S; Cook Meth N/S25002930, 250, 2, 0.02%, Pork, fat-Cooked; Cured etc; Cook Meth N/S95003590, 240, 1, 0.02%, Strawberry-Cooked; Canned; Cook Meth N/S12002600, 240, 2, 0.02%, Peach-Cooked; Canned; Cook Meth N/S25002930, 253, 1, 0.01%, Pork, fat-Cooked; Cured etc; Fried15004020, 212, 1, 0.01%, Wheat, flour-Cooked; Fresh or N/S; Boiled12000120, 240, 1, 0.01%, Apricot-Cooked; Canned; Cook Meth N/S15004010, 230, 2, 0.01%, Wheat, grain-Cooked; Dried; Cook Meth N/S

390

10002410, 120, 1, 0.01%, Orange, juice-Uncooked; Frozen; Cook Meth N/S13010580, 240, 1, 0.01%, Boysenberry-Cooked; Canned; Cook Meth N/S

391

Children 1-2 yrsLow percentile for CEC records: 95 Exposure (mg/day) = 0.000905High percentile for CEC records: 100 Exposure (mg/day) = 0.236331Number of actual records in this interval: 3978

Critical foods/foodforms for this population (as derived from these records): N=number of appearances in all records (including duplicates) %=percent of total exposure for all records (including duplicates)

Food, FF, N , Percent, Food Name --------, ---, -----, -------, -------------12002610, 130, 19, 7.23%, Peach, dried-Uncooked; Dried; Cook Meth N/S95002810, 110, 641, 7.21%, Pineapple, juice-Uncooked; Fresh or N/S; Cook MethN/S12002880, 110, 38, 6.23%, Plum, prune, juice-Uncooked; Fresh or N/S; CookMeth N/S12000910, 210, 717, 6.23%, Cherry, juice-Cooked; Fresh or N/S; Cook Meth N/S12002620, 110, 95, 6.10%, Peach, juice-Uncooked; Fresh or N/S; Cook Meth N/S11000070, 110, 196, 4.48%, Apple, fruit with peel-Uncooked; Fresh or N/S; CookMeth N/S10002000, 110, 377, 3.79%, Lemon, juice-Uncooked; Fresh or N/S; Cook Meth N/S10001810, 110, 244, 3.59%, Grapefruit, juice-Uncooked; Fresh or N/S; Cook MethN/S95001750, 110, 118, 2.61%, Grape-Uncooked; Fresh or N/S; Cook Meth N/S12000910, 110, 81, 2.57%, Cherry, juice-Uncooked; Fresh or N/S; Cook Meth N/S10003690, 110, 202, 2.23%, Tangerine-Uncooked; Fresh or N/S; Cook Meth N/S 5022290, 242, 19, 2.22%, Mustard greens-Cooked; Canned; Boiled11000100, 110, 585, 2.13%, Apple, juice-Uncooked; Fresh or N/S; Cook Meth N/S 8002340, 210, 57, 1.63%, Okra-Cooked; Fresh or N/S; Cook Meth N/S12000911, 240, 120, 1.56%, Cherry, juice-babyfood-Cooked; Canned; Cook MethN/S12002620, 240, 19, 1.50%, Peach, juice-Cooked; Canned; Cook Meth N/S 5020700, 210, 100, 1.43%, Cabbage, Chinese, bok choy-Cooked; Fresh or N/S;Cook Meth N/S10002000, 210, 737, 1.42%, Lemon, juice-Cooked; Fresh or N/S; Cook Meth N/S95002810, 240, 604, 1.34%, Pineapple, juice-Cooked; Canned; Cook Meth N/S12000910, 240, 242, 1.22%, Cherry, juice-Cooked; Canned; Cook Meth N/S13020570, 110, 50, 1.13%, Blueberry-Uncooked; Fresh or N/S; Cook Meth N/S13020570, 211, 56, 1.05%, Blueberry-Cooked; Fresh or N/S; Baked12002600, 240, 77, 1.01%, Peach-Cooked; Canned; Cook Meth N/S 8002720, 212, 129, 0.96%, Pepper, nonbell-Cooked; Fresh or N/S; Boiled10003700, 240, 387, 0.96%, Tangerine, juice-Cooked; Canned; Cook Meth N/S95002350, 240, 15, 0.90%, Olive-Cooked; Canned; Cook Meth N/S 8002340, 220, 39, 0.87%, Okra-Cooked; Frozen; Cook Meth N/S12002881, 240, 38, 0.87%, Plum, prune, juice-babyfood-Cooked; Canned; CookMeth N/S12002621, 240, 19, 0.83%, Peach, juice-babyfood-Cooked; Canned; Cook Meth N/S10002000, 240, 386, 0.83%, Lemon, juice-Cooked; Canned; Cook Meth N/S10002070, 110, 100, 0.78%, Lime, juice-Uncooked; Fresh or N/S; Cook Meth N/S10002070, 240, 362, 0.77%, Lime, juice-Cooked; Canned; Cook Meth N/S12002600, 110, 48, 0.75%, Peach-Uncooked; Fresh or N/S; Cook Meth N/S12002601, 240, 28, 0.70%, Peach-babyfood-Cooked; Canned; Cook Meth N/S95001760, 110, 322, 0.65%, Grape, juice-Uncooked; Fresh or N/S; Cook Meth N/S13013200, 240, 41, 0.59%, Raspberry-Cooked; Canned; Cook Meth N/S10001810, 120, 91, 0.54%, Grapefruit, juice-Uncooked; Frozen; Cook Meth N/S13010580, 240, 366, 0.53%, Boysenberry-Cooked; Canned; Cook Meth N/S10003700, 120, 115, 0.52%, Tangerine, juice-Uncooked; Frozen; Cook Meth N/S10002070, 120, 137, 0.49%, Lime, juice-Uncooked; Frozen; Cook Meth N/S10003700, 110, 81, 0.48%, Tangerine, juice-Uncooked; Fresh or N/S; Cook MethN/S11002660, 110, 29, 0.48%, Pear-Uncooked; Fresh or N/S; Cook Meth N/S 8002340, 213, 63, 0.48%, Okra-Cooked; Fresh or N/S; Fried27002220, 110, 1475, 0.46%, Milk, fat-Uncooked; Fresh or N/S; Cook Meth N/S10002000, 120, 115, 0.46%, Lemon, juice-Uncooked; Frozen; Cook Meth N/S

392

11000090, 211, 107, 0.46%, Apple, dried-Cooked; Fresh or N/S; Baked95001760, 240, 339, 0.43%, Grape, juice-Cooked; Canned; Cook Meth N/S11002660, 240, 22, 0.39%, Pear-Cooked; Canned; Cook Meth N/S10001810, 240, 283, 0.39%, Grapefruit, juice-Cooked; Canned; Cook Meth N/S95003590, 110, 22, 0.35%, Strawberry-Uncooked; Fresh or N/S; Cook Meth N/S13020571, 240, 8, 0.32%, Blueberry-babyfood-Cooked; Canned; Cook Meth N/S11002681, 240, 9, 0.31%, Pear, juice-babyfood-Cooked; Canned; Cook Meth N/S15003250, 230, 224, 0.28%, Rice, flour-Cooked; Dried; Cook Meth N/S 8002720, 215, 29, 0.27%, Pepper, nonbell-Cooked; Fresh or N/S; Boiled/baked13010550, 240, 44, 0.26%, Blackberry-Cooked; Canned; Cook Meth N/S 8002720, 210, 106, 0.25%, Pepper, nonbell-Cooked; Fresh or N/S; Cook Meth N/S11000090, 230, 82, 0.25%, Apple, dried-Cooked; Dried; Cook Meth N/S11000110, 212, 91, 0.24%, Apple, sauce-Cooked; Fresh or N/S; Boiled13013200, 110, 44, 0.23%, Raspberry-Uncooked; Fresh or N/S; Cook Meth N/S11000091, 230, 24, 0.21%, Apple, dried-babyfood-Cooked; Dried; Cook Meth N/S25002930, 210, 423, 0.21%, Pork, fat-Cooked; Fresh or N/S; Cook Meth N/S10002410, 110, 394, 0.20%, Orange, juice-Uncooked; Fresh or N/S; Cook Meth N/S11000101, 240, 132, 0.19%, Apple, juice-babyfood-Cooked; Canned; Cook Meth N/S25002930, 213, 289, 0.19%, Pork, fat-Cooked; Fresh or N/S; Fried95001750, 210, 57, 0.19%, Grape-Cooked; Fresh or N/S; Cook Meth N/S 8002730, 212, 194, 0.19%, Pepper, nonbell, dried-Cooked; Fresh or N/S; Boiled11000100, 240, 174, 0.18%, Apple, juice-Cooked; Canned; Cook Meth N/S 6010430, 242, 19, 0.18%, Bean, snap, succulent-Cooked; Canned; Boiled95002810, 120, 44, 0.18%, Pineapple, juice-Uncooked; Frozen; Cook Meth N/S13013210, 110, 5, 0.17%, Raspberry, juice-Uncooked; Fresh or N/S; Cook MethN/S 8002700, 110, 16, 0.17%, Pepper, bell-Uncooked; Fresh or N/S; Cook Meth N/S13020570, 120, 8, 0.17%, Blueberry-Uncooked; Frozen; Cook Meth N/S13010561, 240, 9, 0.17%, Blackberry, juice-babyfood-Cooked; Canned; CookMeth N/S13010580, 110, 43, 0.16%, Boysenberry-Uncooked; Fresh or N/S; Cook Meth N/S11000081, 240, 13, 0.15%, Apple, peeled fruit-babyfood-Cooked; Canned; CookMeth N/S 8002340, 150, 19, 0.15%, Okra-Uncooked; Cured etc; Cook Meth N/S 8002700, 210, 8, 0.14%, Pepper, bell-Cooked; Fresh or N/S; Cook Meth N/S15001240, 240, 504, 0.13%, Corn, field, syrup-Cooked; Canned; Cook Meth N/S12000130, 130, 6, 0.12%, Apricot, dried-Uncooked; Dried; Cook Meth N/S12000900, 110, 22, 0.11%, Cherry-Uncooked; Fresh or N/S; Cook Meth N/S25002930, 250, 268, 0.11%, Pork, fat-Cooked; Cured etc; Cook Meth N/S10001990, 110, 21, 0.11%, Lemon-Uncooked; Fresh or N/S; Cook Meth N/S13013211, 240, 5, 0.11%, Raspberry, juice-babyfood-Cooked; Canned; Cook MethN/S11002660, 210, 34, 0.11%, Pear-Cooked; Fresh or N/S; Cook Meth N/S12000140, 240, 21, 0.10%, Apricot, juice-Cooked; Canned; Cook Meth N/S 8002730, 240, 165, 0.10%, Pepper, nonbell, dried-Cooked; Canned; Cook MethN/S15004020, 211, 455, 0.10%, Wheat, flour-Cooked; Fresh or N/S; Baked15003251, 230, 73, 0.10%, Rice, flour-babyfood-Cooked; Dried; Cook Meth N/S11002661, 240, 4, 0.09%, Pear-babyfood-Cooked; Canned; Cook Meth N/S 8002720, 150, 20, 0.09%, Pepper, nonbell-Uncooked; Cured etc; Cook Meth N/S95002350, 211, 10, 0.09%, Olive-Cooked; Fresh or N/S; Baked11000100, 120, 27, 0.09%, Apple, juice-Uncooked; Frozen; Cook Meth N/S 8003770, 240, 301, 0.09%, Tomato, puree-Cooked; Canned; Cook Meth N/S13020570, 214, 7, 0.09%, Blueberry-Cooked; Fresh or N/S; Fried/baked10002410, 120, 140, 0.08%, Orange, juice-Uncooked; Frozen; Cook Meth N/S25002930, 253, 134, 0.08%, Pork, fat-Cooked; Cured etc; Fried25002930, 211, 193, 0.08%, Pork, fat-Cooked; Fresh or N/S; Baked 8002730, 210, 99, 0.08%, Pepper, nonbell, dried-Cooked; Fresh or N/S; CookMeth N/S13010580, 120, 78, 0.08%, Boysenberry-Uncooked; Frozen; Cook Meth N/S95003590, 240, 8, 0.08%, Strawberry-Cooked; Canned; Cook Meth N/S 6003490, 210, 40, 0.07%, Soybean, soy milk-Cooked; Fresh or N/S; Cook MethN/S25002900, 250, 266, 0.07%, Pork, meat-Cooked; Cured etc; Cook Meth N/S12000121, 240, 40, 0.07%, Apricot-babyfood-Cooked; Canned; Cook Meth N/S

393

15001240, 110, 315, 0.07%, Corn, field, syrup-Uncooked; Fresh or N/S; CookMeth N/S13020570, 240, 17, 0.07%, Blueberry-Cooked; Canned; Cook Meth N/S12000120, 110, 2, 0.07%, Apricot-Uncooked; Fresh or N/S; Cook Meth N/S10002000, 130, 40, 0.06%, Lemon, juice-Uncooked; Dried; Cook Meth N/S15004020, 232, 215, 0.06%, Wheat, flour-Cooked; Dried; Boiled95003600, 240, 12, 0.06%, Strawberry, juice-Cooked; Canned; Cook Meth N/S21000470, 210, 245, 0.06%, Beef, fat-Cooked; Fresh or N/S; Cook Meth N/S12000141, 240, 6, 0.05%, Apricot, juice-babyfood-Cooked; Canned; Cook MethN/S21000440, 210, 196, 0.04%, Beef, meat-Cooked; Fresh or N/S; Cook Meth N/S10002400, 110, 13, 0.04%, Orange-Uncooked; Fresh or N/S; Cook Meth N/S95001750, 240, 14, 0.04%, Grape-Cooked; Canned; Cook Meth N/S 6010430, 212, 5, 0.04%, Bean, snap, succulent-Cooked; Fresh or N/S; Boiled27002220, 232, 33, 0.04%, Milk, fat-Cooked; Dried; Boiled11000111, 240, 14, 0.04%, Apple, sauce-babyfood-Cooked; Canned; Cook Meth N/S12000901, 240, 2, 0.04%, Cherry-babyfood-Cooked; Canned; Cook Meth N/S 4011500, 110, 47, 0.04%, Endive-Uncooked; Fresh or N/S; Cook Meth N/S14002820, 110, 19, 0.03%, Pistachio-Uncooked; Fresh or N/S; Cook Meth N/S12000120, 240, 5, 0.03%, Apricot-Cooked; Canned; Cook Meth N/S13020570, 213, 6, 0.03%, Blueberry-Cooked; Fresh or N/S; Fried95002360, 900, 50, 0.03%, Olive, oil-Refined; FF N/A; Cook Meth N/S95002811, 240, 19, 0.03%, Pineapple, juice-babyfood-Cooked; Canned; Cook MethN/S10002000, 211, 48, 0.03%, Lemon, juice-Cooked; Fresh or N/S; Baked12002600, 120, 1, 0.03%, Peach-Uncooked; Frozen; Cook Meth N/S95001760, 120, 7, 0.03%, Grape, juice-Uncooked; Frozen; Cook Meth N/S10002410, 240, 83, 0.03%, Orange, juice-Cooked; Canned; Cook Meth N/S13013201, 240, 4, 0.03%, Raspberry-babyfood-Cooked; Canned; Cook Meth N/S 8003790, 212, 27, 0.03%, Tomato, juice-Cooked; Fresh or N/S; Boiled25002900, 211, 55, 0.03%, Pork, meat-Cooked; Fresh or N/S; Baked15001210, 233, 88, 0.03%, Corn, field, meal-Cooked; Dried; Fried 8002700, 213, 3, 0.02%, Pepper, bell-Cooked; Fresh or N/S; Fried95000230, 110, 127, 0.02%, Banana-Uncooked; Fresh or N/S; Cook Meth N/S12000910, 120, 56, 0.02%, Cherry, juice-Uncooked; Frozen; Cook Meth N/S 8003770, 210, 88, 0.02%, Tomato, puree-Cooked; Fresh or N/S; Cook Meth N/S12000130, 211, 3, 0.02%, Apricot, dried-Cooked; Fresh or N/S; Baked15001200, 230, 91, 0.02%, Corn, field, flour-Cooked; Dried; Cook Meth N/S25002900, 213, 85, 0.02%, Pork, meat-Cooked; Fresh or N/S; Fried25002930, 230, 33, 0.02%, Pork, fat-Cooked; Dried; Cook Meth N/S 6010430, 222, 2, 0.02%, Bean, snap, succulent-Cooked; Frozen; Boiled 8002720, 240, 28, 0.02%, Pepper, nonbell-Cooked; Canned; Cook Meth N/S 8002730, 211, 19, 0.02%, Pepper, nonbell, dried-Cooked; Fresh or N/S; Baked95003600, 210, 14, 0.02%, Strawberry, juice-Cooked; Fresh or N/S; Cook MethN/S25002930, 212, 44, 0.02%, Pork, fat-Cooked; Fresh or N/S; Boiled12000900, 211, 5, 0.02%, Cherry-Cooked; Fresh or N/S; Baked11002680, 110, 4, 0.02%, Pear, juice-Uncooked; Fresh or N/S; Cook Meth N/S 9011870, 110, 2, 0.02%, Honeydew melon-Uncooked; Fresh or N/S; Cook MethN/S 8002700, 215, 6, 0.01%, Pepper, bell-Cooked; Fresh or N/S; Boiled/baked 8002700, 211, 9, 0.01%, Pepper, bell-Cooked; Fresh or N/S; Baked25002930, 232, 21, 0.01%, Pork, fat-Cooked; Dried; Boiled 8002730, 232, 38, 0.01%, Pepper, nonbell, dried-Cooked; Dried; Boiled27002220, 210, 59, 0.01%, Milk, fat-Cooked; Fresh or N/S; Cook Meth N/S21000470, 212, 46, 0.01%, Beef, fat-Cooked; Fresh or N/S; Boiled 8003770, 212, 60, 0.01%, Tomato, puree-Cooked; Fresh or N/S; Boiled13013200, 120, 3, 0.01%, Raspberry-Uncooked; Frozen; Cook Meth N/S 1030821, 240, 65, 0.01%, Cassava-babyfood-Cooked; Canned; Cook Meth N/S13013210, 240, 13, 0.01%, Raspberry, juice-Cooked; Canned; Cook Meth N/S 9021350, 110, 10, 0.01%, Cucumber-Uncooked; Fresh or N/S; Cook Meth N/S 9021350, 240, 5, 0.01%, Cucumber-Cooked; Canned; Cook Meth N/S21000440, 211, 37, 0.01%, Beef, meat-Cooked; Fresh or N/S; Baked 2001010, 110, 40, 0.01%, Chicory, tops-Uncooked; Fresh or N/S; Cook Meth N/S15003251, 240, 30, 0.01%, Rice, flour-babyfood-Cooked; Canned; Cook Meth N/S

394

8002720, 232, 19, 0.01%, Pepper, nonbell-Cooked; Dried; Boiled11000080, 110, 1, 0.01%, Apple, peeled fruit-Uncooked; Fresh or N/S; CookMeth N/S 1033000, 212, 15, 0.01%, Potato, tuber, w/o peel-Cooked; Fresh or N/S;Boiled95001761, 240, 16, 0.01%, Grape, juice-babyfood-Cooked; Canned; Cook Meth N/S95002790, 240, 34, 0.01%, Pineapple-Cooked; Canned; Cook Meth N/S15003250, 210, 29, 0.01%, Rice, flour-Cooked; Fresh or N/S; Cook Meth N/S95002640, 210, 40, 0.01%, Peanut, butter-Cooked; Fresh or N/S; Cook Meth N/S15001260, 231, 19, 0.01%, Corn, pop-Cooked; Dried; Baked 9010750, 110, 3, 0.01%, Cantaloupe-Uncooked; Fresh or N/S; Cook Meth N/S15004020, 214, 21, 0.01%, Wheat, flour-Cooked; Fresh or N/S; Fried/baked12000900, 240, 9, 0.01%, Cherry-Cooked; Canned; Cook Meth N/S 4012480, 210, 41, 0.01%, Parsley, leaves-Cooked; Fresh or N/S; Cook Meth N/S11000110, 210, 5, 0.01%, Apple, sauce-Cooked; Fresh or N/S; Cook Meth N/S95001320, 240, 31, 0.01%, Cranberry, juice-Cooked; Canned; Cook Meth N/S21000470, 250, 19, 0.01%, Beef, fat-Cooked; Cured etc; Cook Meth N/S15004020, 212, 44, 0.01%, Wheat, flour-Cooked; Fresh or N/S; Boiled13020570, 210, 2, 0.01%, Blueberry-Cooked; Fresh or N/S; Cook Meth N/S 8002730, 215, 19, 0.01%, Pepper, nonbell, dried-Cooked; Fresh or N/S;Boiled/baked21000440, 213, 48, 0.01%, Beef, meat-Cooked; Fresh or N/S; Fried 8001480, 211, 2, 0.01%, Eggplant-Cooked; Fresh or N/S; Baked15003240, 232, 19, 0.01%, Rice, brown-Cooked; Dried; Boiled 9020880, 210, 1, 0.01%, Chayote, fruit-Cooked; Fresh or N/S; Cook Meth N/S 6030420, 232, 39, 0.01%, Bean, pinto, seed-Cooked; Dried; Boiled15001210, 230, 41, 0.01%, Corn, field, meal-Cooked; Dried; Cook Meth N/S21000440, 212, 34, 0.01%, Beef, meat-Cooked; Fresh or N/S; Boiled95001760, 210, 21, 0.01%, Grape, juice-Cooked; Fresh or N/S; Cook Meth N/S25002930, 240, 11, 0.01%, Pork, fat-Cooked; Canned; Cook Meth N/S15001210, 232, 21, 0.01%, Corn, field, meal-Cooked; Dried; Boiled15001241, 240, 19, 0.01%, Corn, field, syrup-babyfood-Cooked; Canned; CookMeth N/S27002220, 120, 30, 0.01%, Milk, fat-Uncooked; Frozen; Cook Meth N/S21000470, 215, 19, 0.01%, Beef, fat-Cooked; Fresh or N/S; Boiled/baked15001240, 120, 25, 0.01%, Corn, field, syrup-Uncooked; Frozen; Cook Meth N/S13013200, 211, 3, 0.01%, Raspberry-Cooked; Fresh or N/S; Baked15001200, 214, 43, 0.01%, Corn, field, flour-Cooked; Fresh or N/S;Fried/baked12002300, 110, 2, 0.01%, Nectarine-Uncooked; Fresh or N/S; Cook Meth N/S15001210, 210, 19, 0.01%, Corn, field, meal-Cooked; Fresh or N/S; Cook MethN/S15001241, 230, 24, 0.01%, Corn, field, syrup-babyfood-Cooked; Dried; CookMeth N/S 8002720, 213, 20, 0.00%, Pepper, nonbell-Cooked; Fresh or N/S; Fried21000440, 215, 19, 0.00%, Beef, meat-Cooked; Fresh or N/S; Boiled/baked95003590, 211, 1, 0.00%, Strawberry-Cooked; Fresh or N/S; Baked 8003790, 240, 1, 0.00%, Tomato, juice-Cooked; Canned; Cook Meth N/S25002900, 210, 23, 0.00%, Pork, meat-Cooked; Fresh or N/S; Cook Meth N/S 8002720, 110, 1, 0.00%, Pepper, nonbell-Uncooked; Fresh or N/S; Cook MethN/S15001260, 230, 24, 0.00%, Corn, pop-Cooked; Dried; Cook Meth N/S25002931, 240, 27, 0.00%, Pork, fat-babyfood-Cooked; Canned; Cook Meth N/S21000440, 250, 19, 0.00%, Beef, meat-Cooked; Cured etc; Cook Meth N/S15001240, 130, 25, 0.00%, Corn, field, syrup-Uncooked; Dried; Cook Meth N/S11000100, 210, 19, 0.00%, Apple, juice-Cooked; Fresh or N/S; Cook Meth N/S 4012480, 212, 22, 0.00%, Parsley, leaves-Cooked; Fresh or N/S; Boiled15004020, 210, 26, 0.00%, Wheat, flour-Cooked; Fresh or N/S; Cook Meth N/S 1010500, 250, 21, 0.00%, Beet, garden, roots-Cooked; Cured etc; Cook MethN/S21000470, 240, 24, 0.00%, Beef, fat-Cooked; Canned; Cook Meth N/S95003600, 110, 1, 0.00%, Strawberry, juice-Uncooked; Fresh or N/S; Cook MethN/S15001210, 215, 18, 0.00%, Corn, field, meal-Cooked; Fresh or N/S;Boiled/baked

395

8002730, 213, 20, 0.00%, Pepper, nonbell, dried-Cooked; Fresh or N/S; Fried 1013140, 110, 19, 0.00%, Radish, roots-Uncooked; Fresh or N/S; Cook Meth N/S 8003760, 212, 22, 0.00%, Tomato, paste-Cooked; Fresh or N/S; Boiled27002220, 211, 24, 0.00%, Milk, fat-Cooked; Fresh or N/S; Baked27002220, 213, 22, 0.00%, Milk, fat-Cooked; Fresh or N/S; Fried21000470, 211, 25, 0.00%, Beef, fat-Cooked; Fresh or N/S; Baked15004020, 231, 23, 0.00%, Wheat, flour-Cooked; Dried; Baked15004010, 211, 22, 0.00%, Wheat, grain-Cooked; Fresh or N/S; Baked15004020, 230, 22, 0.00%, Wheat, flour-Cooked; Dried; Cook Meth N/S21000470, 213, 19, 0.00%, Beef, fat-Cooked; Fresh or N/S; Fried15001230, 232, 17, 0.00%, Corn, field, starch-Cooked; Dried; Boiled15004020, 240, 18, 0.00%, Wheat, flour-Cooked; Canned; Cook Meth N/S25002920, 232, 19, 0.00%, Pork, meat byproducts-Cooked; Dried; Boiled15001241, 130, 9, 0.00%, Corn, field, syrup-babyfood-Uncooked; Dried; CookMeth N/S95003601, 240, 2, 0.00%, Strawberry, juice-babyfood-Cooked; Canned; CookMeth N/S13010550, 211, 1, 0.00%, Blackberry-Cooked; Fresh or N/S; Baked95001320, 110, 3, 0.00%, Cranberry, juice-Uncooked; Fresh or N/S; Cook MethN/S27002220, 215, 17, 0.00%, Milk, fat-Cooked; Fresh or N/S; Boiled/baked15003240, 210, 1, 0.00%, Rice, brown-Cooked; Fresh or N/S; Cook Meth N/S13010550, 120, 3, 0.00%, Blackberry-Uncooked; Frozen; Cook Meth N/S13013210, 120, 3, 0.00%, Raspberry, juice-Uncooked; Frozen; Cook Meth N/S15001240, 211, 13, 0.00%, Corn, field, syrup-Cooked; Fresh or N/S; Baked13010550, 110, 2, 0.00%, Blackberry-Uncooked; Fresh or N/S; Cook Meth N/S 8003760, 242, 16, 0.00%, Tomato, paste-Cooked; Canned; Boiled25002901, 240, 6, 0.00%, Pork, meat-babyfood-Cooked; Canned; Cook Meth N/S 8002721, 240, 3, 0.00%, Pepper, nonbell-babyfood-Cooked; Canned; Cook MethN/S 1010790, 110, 3, 0.00%, Carrot, juice-Uncooked; Fresh or N/S; Cook Meth N/S11002680, 240, 6, 0.00%, Pear, juice-Cooked; Canned; Cook Meth N/S 4020860, 240, 1, 0.00%, Celery, juice-Cooked; Canned; Cook Meth N/S15001201, 230, 3, 0.00%, Corn, field, flour-babyfood-Cooked; Dried; CookMeth N/S25002930, 221, 1, 0.00%, Pork, fat-Cooked; Frozen; Baked95000190, 242, 2, 0.00%, Asparagus-Cooked; Canned; Boiled 6030420, 230, 6, 0.00%, Bean, pinto, seed-Cooked; Dried; Cook Meth N/S15001231, 240, 4, 0.00%, Corn, field, starch-babyfood-Cooked; Canned; CookMeth N/S 8003750, 110, 5, 0.00%, Tomato-Uncooked; Fresh or N/S; Cook Meth N/S 8003760, 210, 6, 0.00%, Tomato, paste-Cooked; Fresh or N/S; Cook Meth N/S14003910, 211, 3, 0.00%, Walnut-Cooked; Fresh or N/S; Baked15001210, 211, 6, 0.00%, Corn, field, meal-Cooked; Fresh or N/S; Baked21000441, 240, 5, 0.00%, Beef, meat-babyfood-Cooked; Canned; Cook Meth N/S15001200, 210, 3, 0.00%, Corn, field, flour-Cooked; Fresh or N/S; Cook MethN/S21000440, 240, 5, 0.00%, Beef, meat-Cooked; Canned; Cook Meth N/S27002220, 212, 5, 0.00%, Milk, fat-Cooked; Fresh or N/S; Boiled 1033000, 211, 3, 0.00%, Potato, tuber, w/o peel-Cooked; Fresh or N/S; Baked 1032990, 211, 2, 0.00%, Potato, tuber, w/peel-Cooked; Fresh or N/S; Baked 9013990, 110, 4, 0.00%, Watermelon-Uncooked; Fresh or N/S; Cook Meth N/S 1033661, 240, 2, 0.00%, Sweet potato-babyfood-Cooked; Canned; Cook Meth N/S12002600, 210, 1, 0.00%, Peach-Cooked; Fresh or N/S; Cook Meth N/S21000460, 210, 3, 0.00%, Beef, meat byproducts-Cooked; Fresh or N/S; CookMeth N/S 9021350, 150, 1, 0.00%, Cucumber-Uncooked; Cured etc; Cook Meth N/S15004040, 230, 4, 0.00%, Wheat, bran-Cooked; Dried; Cook Meth N/S11002680, 120, 2, 0.00%, Pear, juice-Uncooked; Frozen; Cook Meth N/S15003250, 211, 3, 0.00%, Rice, flour-Cooked; Fresh or N/S; Baked15001270, 222, 1, 0.00%, Corn, sweet-Cooked; Frozen; Boiled 5010830, 212, 3, 0.00%, Cauliflower-Cooked; Fresh or N/S; Boiled 8003750, 215, 2, 0.00%, Tomato-Cooked; Fresh or N/S; Boiled/baked15001240, 212, 4, 0.00%, Corn, field, syrup-Cooked; Fresh or N/S; Boiled

396

15001240, 210, 4, 0.00%, Corn, field, syrup-Cooked; Fresh or N/S; Cook MethN/S 1032990, 212, 1, 0.00%, Potato, tuber, w/peel-Cooked; Fresh or N/S; Boiled15001200, 232, 1, 0.00%, Corn, field, flour-Cooked; Dried; Boiled25002900, 253, 3, 0.00%, Pork, meat-Cooked; Cured etc; Fried 5010690, 110, 3, 0.00%, Cabbage-Uncooked; Fresh or N/S; Cook Meth N/S 4013550, 242, 1, 0.00%, Spinach-Cooked; Canned; Boiled 5010830, 222, 1, 0.00%, Cauliflower-Cooked; Frozen; Boiled 8003790, 110, 1, 0.00%, Tomato, juice-Uncooked; Fresh or N/S; Cook Meth N/S15003240, 215, 2, 0.00%, Rice, brown-Cooked; Fresh or N/S; Boiled/baked19011440, 240, 1, 0.00%, Dillweed-Cooked; Canned; Cook Meth N/S95002790, 110, 2, 0.00%, Pineapple-Uncooked; Fresh or N/S; Cook Meth N/S15001230, 230, 3, 0.00%, Corn, field, starch-Cooked; Dried; Cook Meth N/S15004020, 215, 2, 0.00%, Wheat, flour-Cooked; Fresh or N/S; Boiled/baked 8003750, 212, 2, 0.00%, Tomato-Cooked; Fresh or N/S; Boiled95000230, 240, 1, 0.00%, Banana-Cooked; Canned; Cook Meth N/S10002071, 240, 2, 0.00%, Lime, juice-babyfood-Cooked; Canned; Cook Meth N/S 8003740, 110, 1, 0.00%, Tomatillo-Uncooked; Fresh or N/S; Cook Meth N/S21000470, 221, 2, 0.00%, Beef, fat-Cooked; Frozen; Baked21000440, 221, 2, 0.00%, Beef, meat-Cooked; Frozen; Baked95002630, 211, 2, 0.00%, Peanut-Cooked; Fresh or N/S; Baked11000080, 211, 1, 0.00%, Apple, peeled fruit-Cooked; Fresh or N/S; Baked27002220, 221, 2, 0.00%, Milk, fat-Cooked; Frozen; Baked15001230, 210, 2, 0.00%, Corn, field, starch-Cooked; Fresh or N/S; Cook MethN/S 1010790, 240, 2, 0.00%, Carrot, juice-Cooked; Canned; Cook Meth N/S 8001480, 214, 1, 0.00%, Eggplant-Cooked; Fresh or N/S; Fried/baked95002790, 210, 1, 0.00%, Pineapple-Cooked; Fresh or N/S; Cook Meth N/S25002900, 212, 1, 0.00%, Pork, meat-Cooked; Fresh or N/S; Boiled95002640, 240, 1, 0.00%, Peanut, butter-Cooked; Canned; Cook Meth N/S25002930, 242, 1, 0.00%, Pork, fat-Cooked; Canned; Boiled15004020, 213, 1, 0.00%, Wheat, flour-Cooked; Fresh or N/S; Fried25002920, 210, 1, 0.00%, Pork, meat byproducts-Cooked; Fresh or N/S; CookMeth N/S25002930, 251, 1, 0.00%, Pork, fat-Cooked; Cured etc; Baked15001220, 230, 1, 0.00%, Corn, field, bran-Cooked; Dried; Cook Meth N/S 1033660, 210, 1, 0.00%, Sweet potato-Cooked; Fresh or N/S; Cook Meth N/S15001210, 213, 1, 0.00%, Corn, field, meal-Cooked; Fresh or N/S; Fried15004021, 211, 1, 0.00%, Wheat, flour-babyfood-Cooked; Fresh or N/S; Baked

397

Children 3-5 yrsLow percentile for CEC records: 95 Exposure (mg/day) = 0.000799High percentile for CEC records: 100 Exposure (mg/day) = 0.105161Number of actual records in this interval: 8479

Critical foods/foodforms for this population (as derived from these records): N=number of appearances in all records (including duplicates) %=percent of total exposure for all records (including duplicates)

Food, FF, N , Percent, Food Name --------, ---, -----, -------, -------------12000910, 210, 2290, 8.78%, Cherry, juice-Cooked; Fresh or N/S; Cook Meth N/S12000910, 110, 209, 8.69%, Cherry, juice-Uncooked; Fresh or N/S; Cook Meth N/S13021910, 110, 19, 6.43%, Huckleberry-Uncooked; Fresh or N/S; Cook Meth N/S11000070, 110, 526, 5.40%, Apple, fruit with peel-Uncooked; Fresh or N/S; CookMeth N/S10002000, 110, 1149, 4.92%, Lemon, juice-Uncooked; Fresh or N/S; Cook Meth N/S 5022290, 212, 171, 4.54%, Mustard greens-Cooked; Fresh or N/S; Boiled95002810, 110, 671, 3.24%, Pineapple, juice-Uncooked; Fresh or N/S; Cook MethN/S12002620, 110, 76, 3.04%, Peach, juice-Uncooked; Fresh or N/S; Cook Meth N/S95001750, 110, 248, 2.82%, Grape-Uncooked; Fresh or N/S; Cook Meth N/S10003690, 110, 456, 2.75%, Tangerine-Uncooked; Fresh or N/S; Cook Meth N/S12002620, 240, 62, 2.14%, Peach, juice-Cooked; Canned; Cook Meth N/S 8002340, 210, 114, 2.02%, Okra-Cooked; Fresh or N/S; Cook Meth N/S10002000, 210, 2267, 1.98%, Lemon, juice-Cooked; Fresh or N/S; Cook Meth N/S13020570, 211, 145, 1.83%, Blueberry-Cooked; Fresh or N/S; Baked 4023220, 240, 19, 1.79%, Rhubarb-Cooked; Canned; Cook Meth N/S12002880, 110, 57, 1.75%, Plum, prune, juice-Uncooked; Fresh or N/S; CookMeth N/S 5020700, 210, 194, 1.73%, Cabbage, Chinese, bok choy-Cooked; Fresh or N/S;Cook Meth N/S10003700, 240, 1125, 1.44%, Tangerine, juice-Cooked; Canned; Cook Meth N/S 8002340, 220, 95, 1.28%, Okra-Cooked; Frozen; Cook Meth N/S13020570, 110, 80, 1.21%, Blueberry-Uncooked; Fresh or N/S; Cook Meth N/S95002810, 240, 1208, 1.12%, Pineapple, juice-Cooked; Canned; Cook Meth N/S11000090, 130, 96, 1.06%, Apple, dried-Uncooked; Dried; Cook Meth N/S11000100, 110, 870, 1.03%, Apple, juice-Uncooked; Fresh or N/S; Cook Meth N/S10002000, 130, 461, 0.96%, Lemon, juice-Uncooked; Dried; Cook Meth N/S 5022290, 242, 19, 0.92%, Mustard greens-Cooked; Canned; Boiled12000910, 240, 690, 0.88%, Cherry, juice-Cooked; Canned; Cook Meth N/S13013200, 240, 119, 0.88%, Raspberry-Cooked; Canned; Cook Meth N/S13010580, 240, 1089, 0.88%, Boysenberry-Cooked; Canned; Cook Meth N/S10001810, 110, 277, 0.84%, Grapefruit, juice-Uncooked; Fresh or N/S; Cook MethN/S12002600, 240, 160, 0.83%, Peach-Cooked; Canned; Cook Meth N/S10002000, 240, 1049, 0.79%, Lemon, juice-Cooked; Canned; Cook Meth N/S12002610, 130, 58, 0.78%, Peach, dried-Uncooked; Dried; Cook Meth N/S10002070, 240, 944, 0.70%, Lime, juice-Cooked; Canned; Cook Meth N/S11002670, 130, 77, 0.57%, Pear, dried-Uncooked; Dried; Cook Meth N/S10001810, 120, 276, 0.51%, Grapefruit, juice-Uncooked; Frozen; Cook Meth N/S 8002720, 212, 241, 0.50%, Pepper, nonbell-Cooked; Fresh or N/S; Boiled11002660, 110, 54, 0.49%, Pear-Uncooked; Fresh or N/S; Cook Meth N/S 8002720, 210, 184, 0.48%, Pepper, nonbell-Cooked; Fresh or N/S; Cook Meth N/S95002350, 240, 29, 0.48%, Olive-Cooked; Canned; Cook Meth N/S 8002340, 150, 57, 0.48%, Okra-Uncooked; Cured etc; Cook Meth N/S 9020880, 210, 77, 0.46%, Chayote, fruit-Cooked; Fresh or N/S; Cook Meth N/S11000090, 211, 277, 0.44%, Apple, dried-Cooked; Fresh or N/S; Baked13010580, 120, 260, 0.44%, Boysenberry-Uncooked; Frozen; Cook Meth N/S10002070, 110, 96, 0.44%, Lime, juice-Uncooked; Fresh or N/S; Cook Meth N/S13013210, 110, 21, 0.42%, Raspberry, juice-Uncooked; Fresh or N/S; Cook MethN/S 5020700, 150, 57, 0.42%, Cabbage, Chinese, bok choy-Uncooked; Cured etc;Cook Meth N/S

398

10001810, 240, 789, 0.39%, Grapefruit, juice-Cooked; Canned; Cook Meth N/S95001760, 240, 747, 0.38%, Grape, juice-Cooked; Canned; Cook Meth N/S12002600, 110, 66, 0.37%, Peach-Uncooked; Fresh or N/S; Cook Meth N/S13013200, 110, 54, 0.37%, Raspberry-Uncooked; Fresh or N/S; Cook Meth N/S95001760, 110, 399, 0.33%, Grape, juice-Uncooked; Fresh or N/S; Cook Meth N/S 8002340, 213, 57, 0.29%, Okra-Cooked; Fresh or N/S; Fried13010550, 240, 104, 0.28%, Blackberry-Cooked; Canned; Cook Meth N/S25002930, 210, 1096, 0.25%, Pork, fat-Cooked; Fresh or N/S; Cook Meth N/S10002000, 120, 262, 0.24%, Lemon, juice-Uncooked; Frozen; Cook Meth N/S95003590, 110, 43, 0.23%, Strawberry-Uncooked; Fresh or N/S; Cook Meth N/S13020570, 214, 17, 0.23%, Blueberry-Cooked; Fresh or N/S; Fried/baked15003250, 230, 548, 0.22%, Rice, flour-Cooked; Dried; Cook Meth N/S11002660, 240, 40, 0.22%, Pear-Cooked; Canned; Cook Meth N/S27002220, 110, 1975, 0.22%, Milk, fat-Uncooked; Fresh or N/S; Cook Meth N/S10002410, 110, 777, 0.22%, Orange, juice-Uncooked; Fresh or N/S; Cook Meth N/S 8002720, 213, 41, 0.21%, Pepper, nonbell-Cooked; Fresh or N/S; Fried 8002730, 210, 449, 0.21%, Pepper, nonbell, dried-Cooked; Fresh or N/S; CookMeth N/S95001750, 210, 141, 0.20%, Grape-Cooked; Fresh or N/S; Cook Meth N/S11000100, 240, 368, 0.19%, Apple, juice-Cooked; Canned; Cook Meth N/S11000110, 212, 122, 0.18%, Apple, sauce-Cooked; Fresh or N/S; Boiled15001240, 240, 1415, 0.17%, Corn, field, syrup-Cooked; Canned; Cook Meth N/S95002350, 211, 25, 0.17%, Olive-Cooked; Fresh or N/S; Baked95002810, 120, 223, 0.17%, Pineapple, juice-Uncooked; Frozen; Cook Meth N/S25002930, 213, 475, 0.15%, Pork, fat-Cooked; Fresh or N/S; Fried 8002720, 110, 63, 0.14%, Pepper, nonbell-Uncooked; Fresh or N/S; Cook MethN/S25002930, 250, 621, 0.14%, Pork, fat-Cooked; Cured etc; Cook Meth N/S10002070, 120, 311, 0.13%, Lime, juice-Uncooked; Frozen; Cook Meth N/S25002930, 253, 439, 0.13%, Pork, fat-Cooked; Cured etc; Fried11000090, 230, 270, 0.13%, Apple, dried-Cooked; Dried; Cook Meth N/S12002300, 110, 15, 0.13%, Nectarine-Uncooked; Fresh or N/S; Cook Meth N/S 8002700, 110, 35, 0.12%, Pepper, bell-Uncooked; Fresh or N/S; Cook Meth N/S10003700, 110, 57, 0.12%, Tangerine, juice-Uncooked; Fresh or N/S; Cook MethN/S 8002700, 210, 40, 0.12%, Pepper, bell-Cooked; Fresh or N/S; Cook Meth N/S 9010750, 110, 40, 0.12%, Cantaloupe-Uncooked; Fresh or N/S; Cook Meth N/S13010580, 110, 38, 0.11%, Boysenberry-Uncooked; Fresh or N/S; Cook Meth N/S95003600, 240, 46, 0.11%, Strawberry, juice-Cooked; Canned; Cook Meth N/S10003700, 120, 222, 0.11%, Tangerine, juice-Uncooked; Frozen; Cook Meth N/S13013200, 120, 19, 0.10%, Raspberry-Uncooked; Frozen; Cook Meth N/S15004020, 211, 1168, 0.10%, Wheat, flour-Cooked; Fresh or N/S; Baked25002930, 211, 424, 0.10%, Pork, fat-Cooked; Fresh or N/S; Baked11002660, 210, 92, 0.09%, Pear-Cooked; Fresh or N/S; Cook Meth N/S95002800, 130, 58, 0.09%, Pineapple, dried-Uncooked; Dried; Cook Meth N/S13013210, 240, 60, 0.09%, Raspberry, juice-Cooked; Canned; Cook Meth N/S13021370, 230, 19, 0.08%, Currant, dried-Cooked; Dried; Cook Meth N/S13020570, 120, 24, 0.08%, Blueberry-Uncooked; Frozen; Cook Meth N/S10001070, 110, 19, 0.08%, Citrus hybrids-Uncooked; Fresh or N/S; Cook MethN/S15001240, 110, 726, 0.08%, Corn, field, syrup-Uncooked; Fresh or N/S; CookMeth N/S 6010430, 242, 14, 0.08%, Bean, snap, succulent-Cooked; Canned; Boiled 8002720, 150, 21, 0.07%, Pepper, nonbell-Uncooked; Cured etc; Cook Meth N/S12000910, 120, 217, 0.07%, Cherry, juice-Uncooked; Frozen; Cook Meth N/S21000470, 210, 649, 0.07%, Beef, fat-Cooked; Fresh or N/S; Cook Meth N/S95003590, 240, 19, 0.06%, Strawberry-Cooked; Canned; Cook Meth N/S10002400, 110, 27, 0.06%, Orange-Uncooked; Fresh or N/S; Cook Meth N/S12000900, 110, 36, 0.06%, Cherry-Uncooked; Fresh or N/S; Cook Meth N/S21000440, 210, 543, 0.06%, Beef, meat-Cooked; Fresh or N/S; Cook Meth N/S11000080, 211, 9, 0.06%, Apple, peeled fruit-Cooked; Fresh or N/S; Baked13010550, 110, 4, 0.06%, Blackberry-Uncooked; Fresh or N/S; Cook Meth N/S95001760, 120, 47, 0.05%, Grape, juice-Uncooked; Frozen; Cook Meth N/S12000900, 211, 8, 0.05%, Cherry-Cooked; Fresh or N/S; Baked25002900, 250, 456, 0.05%, Pork, meat-Cooked; Cured etc; Cook Meth N/S

399

10002410, 120, 273, 0.05%, Orange, juice-Uncooked; Frozen; Cook Meth N/S95003600, 210, 68, 0.05%, Strawberry, juice-Cooked; Fresh or N/S; Cook MethN/S 6010430, 212, 10, 0.05%, Bean, snap, succulent-Cooked; Fresh or N/S; Boiled13020570, 213, 8, 0.05%, Blueberry-Cooked; Fresh or N/S; Fried10001990, 110, 61, 0.04%, Lemon-Uncooked; Fresh or N/S; Cook Meth N/S11000100, 120, 17, 0.04%, Apple, juice-Uncooked; Frozen; Cook Meth N/S95003590, 120, 3, 0.04%, Strawberry-Uncooked; Frozen; Cook Meth N/S15001240, 130, 355, 0.04%, Corn, field, syrup-Uncooked; Dried; Cook Meth N/S 8002730, 212, 146, 0.04%, Pepper, nonbell, dried-Cooked; Fresh or N/S; Boiled15001200, 230, 411, 0.04%, Corn, field, flour-Cooked; Dried; Cook Meth N/S10002000, 211, 151, 0.04%, Lemon, juice-Cooked; Fresh or N/S; Baked12000120, 240, 12, 0.04%, Apricot-Cooked; Canned; Cook Meth N/S13020570, 210, 6, 0.04%, Blueberry-Cooked; Fresh or N/S; Cook Meth N/S12000120, 110, 3, 0.04%, Apricot-Uncooked; Fresh or N/S; Cook Meth N/S 8002730, 240, 184, 0.04%, Pepper, nonbell, dried-Cooked; Canned; Cook MethN/S95002360, 900, 157, 0.04%, Olive, oil-Refined; FF N/A; Cook Meth N/S11000080, 240, 6, 0.04%, Apple, peeled fruit-Cooked; Canned; Cook Meth N/S 4012480, 210, 241, 0.03%, Parsley, leaves-Cooked; Fresh or N/S; Cook Meth N/S 8002700, 213, 12, 0.03%, Pepper, bell-Cooked; Fresh or N/S; Fried25002900, 211, 160, 0.03%, Pork, meat-Cooked; Fresh or N/S; Baked 8003770, 240, 283, 0.03%, Tomato, puree-Cooked; Canned; Cook Meth N/S 8002720, 240, 84, 0.03%, Pepper, nonbell-Cooked; Canned; Cook Meth N/S15001210, 233, 286, 0.03%, Corn, field, meal-Cooked; Dried; Fried15003250, 210, 127, 0.03%, Rice, flour-Cooked; Fresh or N/S; Cook Meth N/S95001750, 240, 24, 0.03%, Grape-Cooked; Canned; Cook Meth N/S25002930, 212, 98, 0.03%, Pork, fat-Cooked; Fresh or N/S; Boiled 9021350, 110, 51, 0.03%, Cucumber-Uncooked; Fresh or N/S; Cook Meth N/S13010550, 120, 10, 0.03%, Blackberry-Uncooked; Frozen; Cook Meth N/S11002661, 240, 2, 0.02%, Pear-babyfood-Cooked; Canned; Cook Meth N/S10002410, 240, 203, 0.02%, Orange, juice-Cooked; Canned; Cook Meth N/S15004020, 232, 267, 0.02%, Wheat, flour-Cooked; Dried; Boiled12000141, 240, 2, 0.02%, Apricot, juice-babyfood-Cooked; Canned; Cook MethN/S13020570, 240, 32, 0.02%, Blueberry-Cooked; Canned; Cook Meth N/S25002930, 230, 95, 0.02%, Pork, fat-Cooked; Dried; Cook Meth N/S 8003770, 210, 170, 0.02%, Tomato, puree-Cooked; Fresh or N/S; Cook Meth N/S95003600, 110, 3, 0.02%, Strawberry, juice-Uncooked; Fresh or N/S; Cook MethN/S12000900, 240, 22, 0.02%, Cherry-Cooked; Canned; Cook Meth N/S11000070, 213, 2, 0.02%, Apple, fruit with peel-Cooked; Fresh or N/S; Fried 8002700, 211, 17, 0.02%, Pepper, bell-Cooked; Fresh or N/S; Baked25002900, 213, 176, 0.02%, Pork, meat-Cooked; Fresh or N/S; Fried14000810, 211, 20, 0.02%, Cashew-Cooked; Fresh or N/S; Baked 8002720, 230, 21, 0.02%, Pepper, nonbell-Cooked; Dried; Cook Meth N/S15004020, 210, 184, 0.02%, Wheat, flour-Cooked; Fresh or N/S; Cook Meth N/S21000440, 213, 146, 0.02%, Beef, meat-Cooked; Fresh or N/S; Fried25002930, 240, 25, 0.02%, Pork, fat-Cooked; Canned; Cook Meth N/S12000130, 130, 5, 0.02%, Apricot, dried-Uncooked; Dried; Cook Meth N/S 4011500, 110, 58, 0.02%, Endive-Uncooked; Fresh or N/S; Cook Meth N/S21000440, 211, 148, 0.02%, Beef, meat-Cooked; Fresh or N/S; Baked27002220, 211, 102, 0.01%, Milk, fat-Cooked; Fresh or N/S; Baked 8002700, 222, 2, 0.01%, Pepper, bell-Cooked; Frozen; Boiled27002220, 120, 164, 0.01%, Milk, fat-Uncooked; Frozen; Cook Meth N/S12000130, 211, 3, 0.01%, Apricot, dried-Cooked; Fresh or N/S; Baked 9014000, 110, 19, 0.01%, Watermelon, juice-Uncooked; Fresh or N/S; Cook MethN/S 8003770, 212, 97, 0.01%, Tomato, puree-Cooked; Fresh or N/S; Boiled11002680, 240, 9, 0.01%, Pear, juice-Cooked; Canned; Cook Meth N/S15001210, 230, 137, 0.01%, Corn, field, meal-Cooked; Dried; Cook Meth N/S21000440, 212, 136, 0.01%, Beef, meat-Cooked; Fresh or N/S; Boiled25002900, 210, 115, 0.01%, Pork, meat-Cooked; Fresh or N/S; Cook Meth N/S13020570, 230, 1, 0.01%, Blueberry-Cooked; Dried; Cook Meth N/S 8002720, 215, 71, 0.01%, Pepper, nonbell-Cooked; Fresh or N/S; Boiled/baked

400

6010430, 222, 4, 0.01%, Bean, snap, succulent-Cooked; Frozen; Boiled 9011870, 110, 3, 0.01%, Honeydew melon-Uncooked; Fresh or N/S; Cook MethN/S95001760, 210, 70, 0.01%, Grape, juice-Cooked; Fresh or N/S; Cook Meth N/S25002930, 232, 43, 0.01%, Pork, fat-Cooked; Dried; Boiled 8003760, 210, 121, 0.01%, Tomato, paste-Cooked; Fresh or N/S; Cook Meth N/S21000470, 213, 100, 0.01%, Beef, fat-Cooked; Fresh or N/S; Fried 9020210, 212, 3, 0.01%, Balsam pear-Cooked; Fresh or N/S; Boiled21000470, 212, 92, 0.01%, Beef, fat-Cooked; Fresh or N/S; Boiled13013200, 211, 18, 0.01%, Raspberry-Cooked; Fresh or N/S; Baked95003590, 211, 2, 0.01%, Strawberry-Cooked; Fresh or N/S; Baked15004020, 231, 65, 0.01%, Wheat, flour-Cooked; Dried; Baked15001200, 214, 99, 0.01%, Corn, field, flour-Cooked; Fresh or N/S;Fried/baked95002640, 210, 114, 0.01%, Peanut, butter-Cooked; Fresh or N/S; Cook Meth N/S27002220, 232, 63, 0.01%, Milk, fat-Cooked; Dried; Boiled12000140, 240, 7, 0.01%, Apricot, juice-Cooked; Canned; Cook Meth N/S 8002700, 215, 11, 0.01%, Pepper, bell-Cooked; Fresh or N/S; Boiled/baked95001320, 240, 73, 0.01%, Cranberry, juice-Cooked; Canned; Cook Meth N/S95000230, 110, 88, 0.01%, Banana-Uncooked; Fresh or N/S; Cook Meth N/S 9021350, 240, 20, 0.01%, Cucumber-Cooked; Canned; Cook Meth N/S11002681, 240, 1, 0.01%, Pear, juice-babyfood-Cooked; Canned; Cook Meth N/S13010560, 120, 1, 0.01%, Blackberry, juice-Uncooked; Frozen; Cook Meth N/S27002220, 215, 72, 0.01%, Milk, fat-Cooked; Fresh or N/S; Boiled/baked 4013550, 242, 1, 0.01%, Spinach-Cooked; Canned; Boiled95002790, 110, 37, 0.01%, Pineapple-Uncooked; Fresh or N/S; Cook Meth N/S21000470, 211, 71, 0.01%, Beef, fat-Cooked; Fresh or N/S; Baked12000900, 120, 6, 0.01%, Cherry-Uncooked; Frozen; Cook Meth N/S13013211, 240, 1, 0.01%, Raspberry, juice-babyfood-Cooked; Canned; Cook MethN/S 1033000, 212, 20, 0.01%, Potato, tuber, w/o peel-Cooked; Fresh or N/S;Boiled15001260, 230, 70, 0.01%, Corn, pop-Cooked; Dried; Cook Meth N/S95000190, 212, 3, 0.01%, Asparagus-Cooked; Fresh or N/S; Boiled15001200, 210, 40, 0.01%, Corn, field, flour-Cooked; Fresh or N/S; Cook MethN/S10001990, 210, 20, 0.01%, Lemon-Cooked; Fresh or N/S; Cook Meth N/S15001260, 231, 39, 0.01%, Corn, pop-Cooked; Dried; Baked25002900, 253, 26, 0.01%, Pork, meat-Cooked; Cured etc; Fried 8002700, 212, 5, 0.00%, Pepper, bell-Cooked; Fresh or N/S; Boiled27002220, 210, 65, 0.00%, Milk, fat-Cooked; Fresh or N/S; Cook Meth N/S15003250, 120, 38, 0.00%, Rice, flour-Uncooked; Frozen; Cook Meth N/S15004020, 215, 56, 0.00%, Wheat, flour-Cooked; Fresh or N/S; Boiled/baked11000110, 210, 7, 0.00%, Apple, sauce-Cooked; Fresh or N/S; Cook Meth N/S12002601, 240, 2, 0.00%, Peach-babyfood-Cooked; Canned; Cook Meth N/S15003240, 232, 36, 0.00%, Rice, brown-Cooked; Dried; Boiled 8002700, 150, 8, 0.00%, Pepper, bell-Uncooked; Cured etc; Cook Meth N/S 8002720, 211, 4, 0.00%, Pepper, nonbell-Cooked; Fresh or N/S; Baked15004020, 213, 60, 0.00%, Wheat, flour-Cooked; Fresh or N/S; Fried26003390, 210, 19, 0.00%, Sheep, meat-Cooked; Fresh or N/S; Cook Meth N/S 5020700, 110, 1, 0.00%, Cabbage, Chinese, bok choy-Uncooked; Fresh or N/S;Cook Meth N/S15001240, 120, 40, 0.00%, Corn, field, syrup-Uncooked; Frozen; Cook Meth N/S13021370, 211, 6, 0.00%, Currant, dried-Cooked; Fresh or N/S; Baked95003600, 120, 3, 0.00%, Strawberry, juice-Uncooked; Frozen; Cook Meth N/S14002820, 211, 30, 0.00%, Pistachio-Cooked; Fresh or N/S; Baked13013210, 120, 11, 0.00%, Raspberry, juice-Uncooked; Frozen; Cook Meth N/S 8002340, 212, 20, 0.00%, Okra-Cooked; Fresh or N/S; Boiled25002900, 212, 37, 0.00%, Pork, meat-Cooked; Fresh or N/S; Boiled15004010, 211, 29, 0.00%, Wheat, grain-Cooked; Fresh or N/S; Baked 1034070, 110, 6, 0.00%, Yam bean-Uncooked; Fresh or N/S; Cook Meth N/S95002790, 240, 35, 0.00%, Pineapple-Cooked; Canned; Cook Meth N/S19011440, 240, 21, 0.00%, Dillweed-Cooked; Canned; Cook Meth N/S 4012480, 212, 36, 0.00%, Parsley, leaves-Cooked; Fresh or N/S; Boiled 8002700, 240, 3, 0.00%, Pepper, bell-Cooked; Canned; Cook Meth N/S

401

11000100, 210, 33, 0.00%, Apple, juice-Cooked; Fresh or N/S; Cook Meth N/S 9013990, 110, 22, 0.00%, Watermelon-Uncooked; Fresh or N/S; Cook Meth N/S 1033660, 212, 11, 0.00%, Sweet potato-Cooked; Fresh or N/S; Boiled20003640, 230, 20, 0.00%, Sunflower, seed-Cooked; Dried; Cook Meth N/S15004020, 212, 28, 0.00%, Wheat, flour-Cooked; Fresh or N/S; Boiled 8003790, 240, 22, 0.00%, Tomato, juice-Cooked; Canned; Cook Meth N/S11002680, 110, 1, 0.00%, Pear, juice-Uncooked; Fresh or N/S; Cook Meth N/S21000470, 250, 22, 0.00%, Beef, fat-Cooked; Cured etc; Cook Meth N/S 8002700, 250, 1, 0.00%, Pepper, bell-Cooked; Cured etc; Cook Meth N/S 1030820, 240, 19, 0.00%, Cassava-Cooked; Canned; Cook Meth N/S 1010790, 240, 10, 0.00%, Carrot, juice-Cooked; Canned; Cook Meth N/S10002070, 250, 1, 0.00%, Lime, juice-Cooked; Cured etc; Cook Meth N/S95002350, 210, 1, 0.00%, Olive-Cooked; Fresh or N/S; Cook Meth N/S15001210, 231, 18, 0.00%, Corn, field, meal-Cooked; Dried; Baked 8002730, 221, 18, 0.00%, Pepper, nonbell, dried-Cooked; Frozen; Baked 8003750, 110, 16, 0.00%, Tomato-Uncooked; Fresh or N/S; Cook Meth N/S15004020, 230, 30, 0.00%, Wheat, flour-Cooked; Dried; Cook Meth N/S 6003490, 210, 10, 0.00%, Soybean, soy milk-Cooked; Fresh or N/S; Cook MethN/S26003410, 210, 19, 0.00%, Sheep, fat-Cooked; Fresh or N/S; Cook Meth N/S15003250, 211, 19, 0.00%, Rice, flour-Cooked; Fresh or N/S; Baked12002600, 120, 6, 0.00%, Peach-Uncooked; Frozen; Cook Meth N/S 8002730, 213, 22, 0.00%, Pepper, nonbell, dried-Cooked; Fresh or N/S; Fried15001200, 213, 19, 0.00%, Corn, field, flour-Cooked; Fresh or N/S; Fried27002220, 213, 23, 0.00%, Milk, fat-Cooked; Fresh or N/S; Fried15001240, 210, 20, 0.00%, Corn, field, syrup-Cooked; Fresh or N/S; Cook MethN/S 1033000, 211, 9, 0.00%, Potato, tuber, w/o peel-Cooked; Fresh or N/S; Baked 9023080, 211, 19, 0.00%, Pumpkin-Cooked; Fresh or N/S; Baked15001210, 212, 25, 0.00%, Corn, field, meal-Cooked; Fresh or N/S; Boiled 8001480, 214, 1, 0.00%, Eggplant-Cooked; Fresh or N/S; Fried/baked 8003790, 212, 6, 0.00%, Tomato, juice-Cooked; Fresh or N/S; Boiled95001320, 110, 7, 0.00%, Cranberry, juice-Uncooked; Fresh or N/S; Cook MethN/S 5010690, 110, 20, 0.00%, Cabbage-Uncooked; Fresh or N/S; Cook Meth N/S13013201, 240, 1, 0.00%, Raspberry-babyfood-Cooked; Canned; Cook Meth N/S12002850, 110, 3, 0.00%, Plum-Uncooked; Fresh or N/S; Cook Meth N/S15004010, 212, 19, 0.00%, Wheat, grain-Cooked; Fresh or N/S; Boiled 1032990, 212, 4, 0.00%, Potato, tuber, w/peel-Cooked; Fresh or N/S; Boiled21000440, 250, 19, 0.00%, Beef, meat-Cooked; Cured etc; Cook Meth N/S20003640, 210, 19, 0.00%, Sunflower, seed-Cooked; Fresh or N/S; Cook Meth N/S 8003750, 212, 10, 0.00%, Tomato-Cooked; Fresh or N/S; Boiled15004020, 214, 16, 0.00%, Wheat, flour-Cooked; Fresh or N/S; Fried/baked 1010790, 110, 2, 0.00%, Carrot, juice-Uncooked; Fresh or N/S; Cook Meth N/S95002811, 240, 4, 0.00%, Pineapple, juice-babyfood-Cooked; Canned; Cook MethN/S15001240, 211, 14, 0.00%, Corn, field, syrup-Cooked; Fresh or N/S; Baked15001230, 230, 16, 0.00%, Corn, field, starch-Cooked; Dried; Cook Meth N/S14003910, 211, 2, 0.00%, Walnut-Cooked; Fresh or N/S; Baked15001210, 210, 6, 0.00%, Corn, field, meal-Cooked; Fresh or N/S; Cook MethN/S15003250, 232, 1, 0.00%, Rice, flour-Cooked; Dried; Boiled 2001010, 110, 9, 0.00%, Chicory, tops-Uncooked; Fresh or N/S; Cook Meth N/S95001750, 120, 2, 0.00%, Grape-Uncooked; Frozen; Cook Meth N/S15001210, 211, 8, 0.00%, Corn, field, meal-Cooked; Fresh or N/S; Baked15003240, 211, 3, 0.00%, Rice, brown-Cooked; Fresh or N/S; Baked95002810, 211, 6, 0.00%, Pineapple, juice-Cooked; Fresh or N/S; Baked15004010, 230, 10, 0.00%, Wheat, grain-Cooked; Dried; Cook Meth N/S10002000, 212, 1, 0.00%, Lemon, juice-Cooked; Fresh or N/S; Boiled11000110, 221, 1, 0.00%, Apple, sauce-Cooked; Frozen; Baked95002630, 211, 3, 0.00%, Peanut-Cooked; Fresh or N/S; Baked15001210, 232, 5, 0.00%, Corn, field, meal-Cooked; Dried; Boiled 6003490, 230, 1, 0.00%, Soybean, soy milk-Cooked; Dried; Cook Meth N/S11000110, 240, 1, 0.00%, Apple, sauce-Cooked; Canned; Cook Meth N/S 8002720, 232, 4, 0.00%, Pepper, nonbell-Cooked; Dried; Boiled

402

27002220, 212, 7, 0.00%, Milk, fat-Cooked; Fresh or N/S; Boiled15001200, 231, 7, 0.00%, Corn, field, flour-Cooked; Dried; Baked 8003750, 210, 3, 0.00%, Tomato-Cooked; Fresh or N/S; Cook Meth N/S 1032990, 211, 3, 0.00%, Potato, tuber, w/peel-Cooked; Fresh or N/S; Baked11002680, 120, 3, 0.00%, Pear, juice-Uncooked; Frozen; Cook Meth N/S 1033660, 211, 5, 0.00%, Sweet potato-Cooked; Fresh or N/S; Baked 8003750, 215, 4, 0.00%, Tomato-Cooked; Fresh or N/S; Boiled/baked15001200, 211, 2, 0.00%, Corn, field, flour-Cooked; Fresh or N/S; Baked15001231, 240, 3, 0.00%, Corn, field, starch-babyfood-Cooked; Canned; CookMeth N/S12002600, 210, 1, 0.00%, Peach-Cooked; Fresh or N/S; Cook Meth N/S15004010, 231, 7, 0.00%, Wheat, grain-Cooked; Dried; Baked10002000, 232, 2, 0.00%, Lemon, juice-Cooked; Dried; Boiled27002220, 230, 3, 0.00%, Milk, fat-Cooked; Dried; Cook Meth N/S15001240, 212, 4, 0.00%, Corn, field, syrup-Cooked; Fresh or N/S; Boiled 5010830, 212, 4, 0.00%, Cauliflower-Cooked; Fresh or N/S; Boiled20003640, 211, 2, 0.00%, Sunflower, seed-Cooked; Fresh or N/S; Baked 6030420, 232, 3, 0.00%, Bean, pinto, seed-Cooked; Dried; Boiled25002930, 251, 2, 0.00%, Pork, fat-Cooked; Cured etc; Baked12000901, 240, 1, 0.00%, Cherry-babyfood-Cooked; Canned; Cook Meth N/S 8003750, 240, 4, 0.00%, Tomato-Cooked; Canned; Cook Meth N/S25002920, 210, 2, 0.00%, Pork, meat byproducts-Cooked; Fresh or N/S; CookMeth N/S25002930, 221, 1, 0.00%, Pork, fat-Cooked; Frozen; Baked 6003480, 210, 3, 0.00%, Soybean, flour-Cooked; Fresh or N/S; Cook Meth N/S 8002730, 211, 3, 0.00%, Pepper, nonbell, dried-Cooked; Fresh or N/S; Baked20003650, 900, 2, 0.00%, Sunflower, oil-Refined; FF N/A; Cook Meth N/S 1033660, 210, 2, 0.00%, Sweet potato-Cooked; Fresh or N/S; Cook Meth N/S 8002710, 213, 1, 0.00%, Pepper, bell, dried-Cooked; Fresh or N/S; Fried 8003770, 211, 3, 0.00%, Tomato, puree-Cooked; Fresh or N/S; Baked 6003470, 232, 1, 0.00%, Soybean, seed-Cooked; Dried; Boiled23001690, 212, 1, 0.00%, Goat, meat-Cooked; Fresh or N/S; Boiled25002900, 251, 1, 0.00%, Pork, meat-Cooked; Cured etc; Baked 8003760, 212, 2, 0.00%, Tomato, paste-Cooked; Fresh or N/S; Boiled21000440, 240, 2, 0.00%, Beef, meat-Cooked; Canned; Cook Meth N/S21000440, 214, 2, 0.00%, Beef, meat-Cooked; Fresh or N/S; Fried/baked25002900, 240, 1, 0.00%, Pork, meat-Cooked; Canned; Cook Meth N/S15001270, 222, 1, 0.00%, Corn, sweet-Cooked; Frozen; Boiled15001241, 130, 1, 0.00%, Corn, field, syrup-babyfood-Uncooked; Dried; CookMeth N/S 4012480, 110, 1, 0.00%, Parsley, leaves-Uncooked; Fresh or N/S; Cook MethN/S 8002730, 232, 2, 0.00%, Pepper, nonbell, dried-Cooked; Dried; Boiled 6030420, 230, 2, 0.00%, Bean, pinto, seed-Cooked; Dried; Cook Meth N/S 8003750, 211, 1, 0.00%, Tomato-Cooked; Fresh or N/S; Baked25002931, 240, 1, 0.00%, Pork, fat-babyfood-Cooked; Canned; Cook Meth N/S15001240, 230, 1, 0.00%, Corn, field, syrup-Cooked; Dried; Cook Meth N/S95001780, 130, 1, 0.00%, Grape, raisin-Uncooked; Dried; Cook Meth N/S95001761, 240, 1, 0.00%, Grape, juice-babyfood-Cooked; Canned; Cook Meth N/S 4020860, 240, 1, 0.00%, Celery, juice-Cooked; Canned; Cook Meth N/S21000441, 240, 1, 0.00%, Beef, meat-babyfood-Cooked; Canned; Cook Meth N/S25002901, 240, 1, 0.00%, Pork, meat-babyfood-Cooked; Canned; Cook Meth N/S25002920, 232, 1, 0.00%, Pork, meat byproducts-Cooked; Dried; Boiled12002600, 211, 1, 0.00%, Peach-Cooked; Fresh or N/S; Baked21000470, 240, 1, 0.00%, Beef, fat-Cooked; Canned; Cook Meth N/S 6030420, 210, 1, 0.00%, Bean, pinto, seed-Cooked; Fresh or N/S; Cook MethN/S14000030, 230, 1, 0.00%, Almond-Cooked; Dried; Cook Meth N/S95000190, 242, 1, 0.00%, Asparagus-Cooked; Canned; Boiled15004020, 240, 1, 0.00%, Wheat, flour-Cooked; Canned; Cook Meth N/S15001230, 210, 1, 0.00%, Corn, field, starch-Cooked; Fresh or N/S; Cook MethN/S 6030400, 212, 1, 0.00%, Bean, navy, seed-Cooked; Fresh or N/S; Boiled 6030350, 210, 1, 0.00%, Bean, great northern, seed-Cooked; Fresh or N/S;Cook Meth N/S

403

6030400, 210, 1, 0.00%, Bean, navy, seed-Cooked; Fresh or N/S; Cook MethN/S20003640, 110, 1, 0.00%, Sunflower, seed-Uncooked; Fresh or N/S; Cook MethN/S95002790, 211, 1, 0.00%, Pineapple-Cooked; Fresh or N/S; Baked21000470, 253, 1, 0.00%, Beef, fat-Cooked; Cured etc; Fried15003240, 210, 1, 0.00%, Rice, brown-Cooked; Fresh or N/S; Cook Meth N/S15004040, 230, 1, 0.00%, Wheat, bran-Cooked; Dried; Cook Meth N/S95000230, 120, 1, 0.00%, Banana-Uncooked; Frozen; Cook Meth N/S

404

Children 6-12 yrsLow percentile for CEC records: 95 Exposure (mg/day) = 0.000524High percentile for CEC records: 100 Exposure (mg/day) = 0.054824Number of actual records in this interval: 4304

Critical foods/foodforms for this population (as derived from these records): N=number of appearances in all records (including duplicates) %=percent of total exposure for all records (including duplicates)

Food, FF, N , Percent, Food Name --------, ---, -----, -------, -------------12000910, 210, 1144, 11.18%, Cherry, juice-Cooked; Fresh or N/S; Cook Meth N/S12000910, 110, 57, 6.05%, Cherry, juice-Uncooked; Fresh or N/S; Cook Meth N/S10002000, 110, 569, 5.72%, Lemon, juice-Uncooked; Fresh or N/S; Cook Meth N/S 5022290, 242, 19, 4.44%, Mustard greens-Cooked; Canned; Boiled12002620, 240, 77, 3.81%, Peach, juice-Cooked; Canned; Cook Meth N/S11000070, 110, 179, 3.68%, Apple, fruit with peel-Uncooked; Fresh or N/S; CookMeth N/S 5020700, 210, 171, 3.02%, Cabbage, Chinese, bok choy-Cooked; Fresh or N/S;Cook Meth N/S95002810, 110, 297, 2.78%, Pineapple, juice-Uncooked; Fresh or N/S; Cook MethN/S10002000, 210, 1140, 2.53%, Lemon, juice-Cooked; Fresh or N/S; Cook Meth N/S 5022290, 222, 19, 2.39%, Mustard greens-Cooked; Frozen; Boiled12002610, 130, 95, 2.37%, Peach, dried-Uncooked; Dried; Cook Meth N/S11000090, 130, 114, 2.30%, Apple, dried-Uncooked; Dried; Cook Meth N/S 8002720, 110, 154, 2.18%, Pepper, nonbell-Uncooked; Fresh or N/S; Cook MethN/S 8002340, 210, 76, 2.07%, Okra-Cooked; Fresh or N/S; Cook Meth N/S 8002720, 210, 305, 1.79%, Pepper, nonbell-Cooked; Fresh or N/S; Cook Meth N/S13020570, 211, 80, 1.69%, Blueberry-Cooked; Fresh or N/S; Baked10003700, 240, 703, 1.55%, Tangerine, juice-Cooked; Canned; Cook Meth N/S 5022290, 212, 76, 1.44%, Mustard greens-Cooked; Fresh or N/S; Boiled12002620, 110, 19, 1.44%, Peach, juice-Uncooked; Fresh or N/S; Cook Meth N/S10001810, 110, 181, 1.39%, Grapefruit, juice-Uncooked; Fresh or N/S; Cook MethN/S95001750, 110, 70, 1.38%, Grape-Uncooked; Fresh or N/S; Cook Meth N/S10002000, 240, 701, 1.36%, Lemon, juice-Cooked; Canned; Cook Meth N/S 5020700, 150, 95, 1.31%, Cabbage, Chinese, bok choy-Uncooked; Cured etc;Cook Meth N/S10002070, 240, 634, 1.23%, Lime, juice-Cooked; Canned; Cook Meth N/S11000090, 211, 213, 1.23%, Apple, dried-Cooked; Fresh or N/S; Baked 4020860, 110, 19, 1.16%, Celery, juice-Uncooked; Fresh or N/S; Cook Meth N/S 4023220, 211, 19, 0.93%, Rhubarb-Cooked; Fresh or N/S; Baked 9020880, 210, 76, 0.92%, Chayote, fruit-Cooked; Fresh or N/S; Cook Meth N/S95002810, 240, 585, 0.88%, Pineapple, juice-Cooked; Canned; Cook Meth N/S 8002340, 220, 19, 0.86%, Okra-Cooked; Frozen; Cook Meth N/S13013200, 240, 53, 0.85%, Raspberry-Cooked; Canned; Cook Meth N/S95002350, 240, 19, 0.85%, Olive-Cooked; Canned; Cook Meth N/S 8002720, 212, 140, 0.76%, Pepper, nonbell-Cooked; Fresh or N/S; Boiled10001810, 240, 526, 0.68%, Grapefruit, juice-Cooked; Canned; Cook Meth N/S13010580, 240, 559, 0.66%, Boysenberry-Cooked; Canned; Cook Meth N/S95002810, 120, 87, 0.61%, Pineapple, juice-Uncooked; Frozen; Cook Meth N/S11002670, 130, 95, 0.60%, Pear, dried-Uncooked; Dried; Cook Meth N/S13020570, 110, 35, 0.58%, Blueberry-Uncooked; Fresh or N/S; Cook Meth N/S12002600, 240, 56, 0.54%, Peach-Cooked; Canned; Cook Meth N/S25002930, 210, 746, 0.52%, Pork, fat-Cooked; Fresh or N/S; Cook Meth N/S10002000, 130, 135, 0.49%, Lemon, juice-Uncooked; Dried; Cook Meth N/S10003690, 110, 63, 0.49%, Tangerine-Uncooked; Fresh or N/S; Cook Meth N/S12002600, 110, 29, 0.48%, Peach-Uncooked; Fresh or N/S; Cook Meth N/S13021360, 110, 19, 0.46%, Currant-Uncooked; Fresh or N/S; Cook Meth N/S12000910, 240, 286, 0.43%, Cherry, juice-Cooked; Canned; Cook Meth N/S13010550, 240, 65, 0.42%, Blackberry-Cooked; Canned; Cook Meth N/S11000100, 110, 280, 0.40%, Apple, juice-Uncooked; Fresh or N/S; Cook Meth N/S

405

8002720, 240, 239, 0.38%, Pepper, nonbell-Cooked; Canned; Cook Meth N/S 8002340, 213, 38, 0.37%, Okra-Cooked; Fresh or N/S; Fried15001240, 240, 1363, 0.36%, Corn, field, syrup-Cooked; Canned; Cook Meth N/S25002930, 213, 246, 0.32%, Pork, fat-Cooked; Fresh or N/S; Fried11002660, 110, 15, 0.32%, Pear-Uncooked; Fresh or N/S; Cook Meth N/S 8002720, 213, 85, 0.31%, Pepper, nonbell-Cooked; Fresh or N/S; Fried 8002340, 222, 19, 0.30%, Okra-Cooked; Frozen; Boiled12000900, 110, 20, 0.30%, Cherry-Uncooked; Fresh or N/S; Cook Meth N/S12000900, 211, 20, 0.29%, Cherry-Cooked; Fresh or N/S; Baked95002800, 130, 95, 0.28%, Pineapple, dried-Uncooked; Dried; Cook Meth N/S 8002730, 210, 170, 0.25%, Pepper, nonbell, dried-Cooked; Fresh or N/S; CookMeth N/S25002930, 250, 377, 0.25%, Pork, fat-Cooked; Cured etc; Cook Meth N/S95001760, 240, 330, 0.24%, Grape, juice-Cooked; Canned; Cook Meth N/S95001750, 210, 59, 0.23%, Grape-Cooked; Fresh or N/S; Cook Meth N/S27002220, 110, 1000, 0.23%, Milk, fat-Uncooked; Fresh or N/S; Cook Meth N/S10002070, 110, 20, 0.21%, Lime, juice-Uncooked; Fresh or N/S; Cook Meth N/S 8002340, 150, 19, 0.21%, Okra-Uncooked; Cured etc; Cook Meth N/S13013210, 120, 6, 0.19%, Raspberry, juice-Uncooked; Frozen; Cook Meth N/S13010550, 110, 6, 0.19%, Blackberry-Uncooked; Fresh or N/S; Cook Meth N/S95002350, 211, 17, 0.18%, Olive-Cooked; Fresh or N/S; Baked95003590, 110, 17, 0.18%, Strawberry-Uncooked; Fresh or N/S; Cook Meth N/S 8002700, 210, 29, 0.17%, Pepper, bell-Cooked; Fresh or N/S; Cook Meth N/S11000110, 212, 65, 0.17%, Apple, sauce-Cooked; Fresh or N/S; Boiled15004020, 211, 857, 0.17%, Wheat, flour-Cooked; Fresh or N/S; Baked10002410, 110, 425, 0.16%, Orange, juice-Uncooked; Fresh or N/S; Cook Meth N/S15003250, 230, 170, 0.15%, Rice, flour-Cooked; Dried; Cook Meth N/S 8002700, 110, 23, 0.15%, Pepper, bell-Uncooked; Fresh or N/S; Cook Meth N/S95001760, 110, 145, 0.14%, Grape, juice-Uncooked; Fresh or N/S; Cook Meth N/S11002660, 240, 15, 0.14%, Pear-Cooked; Canned; Cook Meth N/S13020570, 214, 6, 0.12%, Blueberry-Cooked; Fresh or N/S; Fried/baked10001070, 110, 19, 0.12%, Citrus hybrids-Uncooked; Fresh or N/S; Cook MethN/S25002930, 253, 136, 0.11%, Pork, fat-Cooked; Cured etc; Fried25002900, 250, 281, 0.11%, Pork, meat-Cooked; Cured etc; Cook Meth N/S13013200, 110, 18, 0.11%, Raspberry-Uncooked; Fresh or N/S; Cook Meth N/S15003250, 210, 167, 0.10%, Rice, flour-Cooked; Fresh or N/S; Cook Meth N/S10001990, 110, 42, 0.10%, Lemon-Uncooked; Fresh or N/S; Cook Meth N/S25002930, 240, 76, 0.10%, Pork, fat-Cooked; Canned; Cook Meth N/S11002660, 210, 37, 0.09%, Pear-Cooked; Fresh or N/S; Cook Meth N/S15001240, 110, 452, 0.09%, Corn, field, syrup-Uncooked; Fresh or N/S; CookMeth N/S11000090, 230, 78, 0.09%, Apple, dried-Cooked; Dried; Cook Meth N/S11000080, 211, 7, 0.08%, Apple, peeled fruit-Cooked; Fresh or N/S; Baked21000440, 210, 361, 0.08%, Beef, meat-Cooked; Fresh or N/S; Cook Meth N/S 6010430, 242, 9, 0.08%, Bean, snap, succulent-Cooked; Canned; Boiled13020570, 210, 3, 0.08%, Blueberry-Cooked; Fresh or N/S; Cook Meth N/S95003590, 240, 8, 0.07%, Strawberry-Cooked; Canned; Cook Meth N/S95002350, 212, 1, 0.07%, Olive-Cooked; Fresh or N/S; Boiled12000900, 120, 3, 0.07%, Cherry-Uncooked; Frozen; Cook Meth N/S10002000, 211, 127, 0.07%, Lemon, juice-Cooked; Fresh or N/S; Baked13010580, 120, 52, 0.07%, Boysenberry-Uncooked; Frozen; Cook Meth N/S 8002730, 212, 75, 0.07%, Pepper, nonbell, dried-Cooked; Fresh or N/S; Boiled15001210, 233, 153, 0.07%, Corn, field, meal-Cooked; Dried; Fried11000100, 240, 122, 0.07%, Apple, juice-Cooked; Canned; Cook Meth N/S95003600, 240, 16, 0.07%, Strawberry, juice-Cooked; Canned; Cook Meth N/S13020570, 213, 4, 0.06%, Blueberry-Cooked; Fresh or N/S; Fried25002930, 211, 225, 0.06%, Pork, fat-Cooked; Fresh or N/S; Baked95003600, 210, 34, 0.06%, Strawberry, juice-Cooked; Fresh or N/S; Cook MethN/S25002930, 230, 74, 0.06%, Pork, fat-Cooked; Dried; Cook Meth N/S10002070, 120, 76, 0.06%, Lime, juice-Uncooked; Frozen; Cook Meth N/S10002400, 110, 10, 0.06%, Orange-Uncooked; Fresh or N/S; Cook Meth N/S13013210, 110, 3, 0.06%, Raspberry, juice-Uncooked; Fresh or N/S; Cook MethN/S

406

21000470, 210, 320, 0.06%, Beef, fat-Cooked; Fresh or N/S; Cook Meth N/S 4012480, 210, 113, 0.05%, Parsley, leaves-Cooked; Fresh or N/S; Cook Meth N/S 8002730, 213, 123, 0.05%, Pepper, nonbell, dried-Cooked; Fresh or N/S; Fried25002900, 213, 118, 0.05%, Pork, meat-Cooked; Fresh or N/S; Fried10002060, 110, 19, 0.05%, Lime-Uncooked; Fresh or N/S; Cook Meth N/S15001210, 230, 219, 0.05%, Corn, field, meal-Cooked; Dried; Cook Meth N/S27002220, 120, 239, 0.05%, Milk, fat-Uncooked; Frozen; Cook Meth N/S13013200, 211, 7, 0.04%, Raspberry-Cooked; Fresh or N/S; Baked21000440, 213, 177, 0.04%, Beef, meat-Cooked; Fresh or N/S; Fried 9021350, 240, 23, 0.04%, Cucumber-Cooked; Canned; Cook Meth N/S25002900, 210, 123, 0.04%, Pork, meat-Cooked; Fresh or N/S; Cook Meth N/S10002000, 232, 20, 0.04%, Lemon, juice-Cooked; Dried; Boiled 9010750, 110, 9, 0.04%, Cantaloupe-Uncooked; Fresh or N/S; Cook Meth N/S95002360, 900, 51, 0.04%, Olive, oil-Refined; FF N/A; Cook Meth N/S10002000, 120, 53, 0.04%, Lemon, juice-Uncooked; Frozen; Cook Meth N/S12000120, 240, 3, 0.04%, Apricot-Cooked; Canned; Cook Meth N/S10003700, 120, 52, 0.04%, Tangerine, juice-Uncooked; Frozen; Cook Meth N/S12002600, 120, 3, 0.04%, Peach-Uncooked; Frozen; Cook Meth N/S15004020, 232, 157, 0.04%, Wheat, flour-Cooked; Dried; Boiled 9021350, 110, 33, 0.04%, Cucumber-Uncooked; Fresh or N/S; Cook Meth N/S15004020, 210, 136, 0.03%, Wheat, flour-Cooked; Fresh or N/S; Cook Meth N/S 8002730, 240, 47, 0.03%, Pepper, nonbell, dried-Cooked; Canned; Cook MethN/S12002300, 110, 6, 0.03%, Nectarine-Uncooked; Fresh or N/S; Cook Meth N/S 8003770, 240, 120, 0.03%, Tomato, puree-Cooked; Canned; Cook Meth N/S12000120, 211, 1, 0.03%, Apricot-Cooked; Fresh or N/S; Baked10002410, 120, 53, 0.03%, Orange, juice-Uncooked; Frozen; Cook Meth N/S 8003770, 210, 97, 0.03%, Tomato, puree-Cooked; Fresh or N/S; Cook Meth N/S 8002700, 211, 9, 0.03%, Pepper, bell-Cooked; Fresh or N/S; Baked 8003770, 212, 74, 0.03%, Tomato, puree-Cooked; Fresh or N/S; Boiled12000130, 130, 21, 0.03%, Apricot, dried-Uncooked; Dried; Cook Meth N/S15001240, 130, 111, 0.03%, Corn, field, syrup-Uncooked; Dried; Cook Meth N/S95001750, 240, 13, 0.02%, Grape-Cooked; Canned; Cook Meth N/S21000470, 213, 135, 0.02%, Beef, fat-Cooked; Fresh or N/S; Fried14002820, 211, 40, 0.02%, Pistachio-Cooked; Fresh or N/S; Baked12000910, 120, 51, 0.02%, Cherry, juice-Uncooked; Frozen; Cook Meth N/S 8003760, 210, 84, 0.02%, Tomato, paste-Cooked; Fresh or N/S; Cook Meth N/S 8002700, 222, 4, 0.02%, Pepper, bell-Cooked; Frozen; Boiled15001200, 230, 95, 0.02%, Corn, field, flour-Cooked; Dried; Cook Meth N/S15001200, 214, 69, 0.02%, Corn, field, flour-Cooked; Fresh or N/S;Fried/baked12000900, 240, 11, 0.02%, Cherry-Cooked; Canned; Cook Meth N/S21000440, 212, 77, 0.02%, Beef, meat-Cooked; Fresh or N/S; Boiled13013210, 240, 23, 0.02%, Raspberry, juice-Cooked; Canned; Cook Meth N/S13020570, 240, 14, 0.02%, Blueberry-Cooked; Canned; Cook Meth N/S 8002700, 215, 4, 0.02%, Pepper, bell-Cooked; Fresh or N/S; Boiled/baked12002850, 110, 8, 0.02%, Plum-Uncooked; Fresh or N/S; Cook Meth N/S10002410, 240, 60, 0.02%, Orange, juice-Cooked; Canned; Cook Meth N/S 6010430, 212, 3, 0.02%, Bean, snap, succulent-Cooked; Fresh or N/S; Boiled95002640, 210, 76, 0.02%, Peanut, butter-Cooked; Fresh or N/S; Cook Meth N/S13013200, 120, 4, 0.02%, Raspberry-Uncooked; Frozen; Cook Meth N/S12000130, 211, 1, 0.01%, Apricot, dried-Cooked; Fresh or N/S; Baked95003590, 120, 1, 0.01%, Strawberry-Uncooked; Frozen; Cook Meth N/S27002220, 210, 86, 0.01%, Milk, fat-Cooked; Fresh or N/S; Cook Meth N/S12000140, 240, 8, 0.01%, Apricot, juice-Cooked; Canned; Cook Meth N/S 1010790, 110, 19, 0.01%, Carrot, juice-Uncooked; Fresh or N/S; Cook Meth N/S21000440, 211, 67, 0.01%, Beef, meat-Cooked; Fresh or N/S; Baked95001760, 210, 34, 0.01%, Grape, juice-Cooked; Fresh or N/S; Cook Meth N/S15003250, 120, 40, 0.01%, Rice, flour-Uncooked; Frozen; Cook Meth N/S13020570, 120, 5, 0.01%, Blueberry-Uncooked; Frozen; Cook Meth N/S 8002700, 213, 4, 0.01%, Pepper, bell-Cooked; Fresh or N/S; Fried25002900, 240, 52, 0.01%, Pork, meat-Cooked; Canned; Cook Meth N/S 8002700, 212, 6, 0.01%, Pepper, bell-Cooked; Fresh or N/S; Boiled15004020, 231, 49, 0.01%, Wheat, flour-Cooked; Dried; Baked

407

15001240, 210, 42, 0.01%, Corn, field, syrup-Cooked; Fresh or N/S; Cook MethN/S11002680, 240, 9, 0.01%, Pear, juice-Cooked; Canned; Cook Meth N/S10001810, 120, 47, 0.01%, Grapefruit, juice-Uncooked; Frozen; Cook Meth N/S 8002720, 232, 20, 0.01%, Pepper, nonbell-Cooked; Dried; Boiled15004020, 215, 64, 0.01%, Wheat, flour-Cooked; Fresh or N/S; Boiled/baked95000230, 110, 47, 0.01%, Banana-Uncooked; Fresh or N/S; Cook Meth N/S 8002700, 150, 14, 0.01%, Pepper, bell-Uncooked; Cured etc; Cook Meth N/S15001260, 230, 41, 0.01%, Corn, pop-Cooked; Dried; Cook Meth N/S27002220, 215, 48, 0.01%, Milk, fat-Cooked; Fresh or N/S; Boiled/baked25002930, 212, 35, 0.01%, Pork, fat-Cooked; Fresh or N/S; Boiled 1033000, 212, 11, 0.01%, Potato, tuber, w/o peel-Cooked; Fresh or N/S;Boiled15001200, 213, 45, 0.01%, Corn, field, flour-Cooked; Fresh or N/S; Fried21000470, 250, 19, 0.01%, Beef, fat-Cooked; Cured etc; Cook Meth N/S 8002700, 240, 1, 0.01%, Pepper, bell-Cooked; Canned; Cook Meth N/S 9023090, 211, 19, 0.01%, Pumpkin, seed-Cooked; Fresh or N/S; Baked11000100, 120, 2, 0.01%, Apple, juice-Uncooked; Frozen; Cook Meth N/S11000070, 211, 1, 0.01%, Apple, fruit with peel-Cooked; Fresh or N/S; Baked 9023080, 211, 22, 0.01%, Pumpkin-Cooked; Fresh or N/S; Baked27002220, 211, 29, 0.01%, Milk, fat-Cooked; Fresh or N/S; Baked21000470, 211, 42, 0.01%, Beef, fat-Cooked; Fresh or N/S; Baked27002220, 214, 19, 0.01%, Milk, fat-Cooked; Fresh or N/S; Fried/baked15001200, 210, 29, 0.01%, Corn, field, flour-Cooked; Fresh or N/S; Cook MethN/S20003640, 110, 19, 0.01%, Sunflower, seed-Uncooked; Fresh or N/S; Cook MethN/S 6010430, 222, 1, 0.01%, Bean, snap, succulent-Cooked; Frozen; Boiled15004010, 230, 19, 0.01%, Wheat, grain-Cooked; Dried; Cook Meth N/S95002790, 240, 21, 0.01%, Pineapple-Cooked; Canned; Cook Meth N/S 8002720, 215, 6, 0.01%, Pepper, nonbell-Cooked; Fresh or N/S; Boiled/baked 9013990, 110, 7, 0.01%, Watermelon-Uncooked; Fresh or N/S; Cook Meth N/S15001210, 232, 23, 0.00%, Corn, field, meal-Cooked; Dried; Boiled25002930, 222, 19, 0.00%, Pork, fat-Cooked; Frozen; Boiled 8002730, 232, 20, 0.00%, Pepper, nonbell, dried-Cooked; Dried; Boiled25002900, 211, 14, 0.00%, Pork, meat-Cooked; Fresh or N/S; Baked15001240, 120, 24, 0.00%, Corn, field, syrup-Uncooked; Frozen; Cook Meth N/S27002220, 232, 25, 0.00%, Milk, fat-Cooked; Dried; Boiled 8003750, 110, 15, 0.00%, Tomato-Uncooked; Fresh or N/S; Cook Meth N/S15001210, 210, 19, 0.00%, Corn, field, meal-Cooked; Fresh or N/S; Cook MethN/S21000440, 250, 19, 0.00%, Beef, meat-Cooked; Cured etc; Cook Meth N/S 1013140, 110, 19, 0.00%, Radish, roots-Uncooked; Fresh or N/S; Cook Meth N/S 4011500, 110, 8, 0.00%, Endive-Uncooked; Fresh or N/S; Cook Meth N/S 6030390, 232, 18, 0.00%, Bean, mung, seed-Cooked; Dried; Boiled 8003790, 240, 4, 0.00%, Tomato, juice-Cooked; Canned; Cook Meth N/S11000100, 210, 12, 0.00%, Apple, juice-Cooked; Fresh or N/S; Cook Meth N/S 6030420, 230, 24, 0.00%, Bean, pinto, seed-Cooked; Dried; Cook Meth N/S 5010690, 110, 20, 0.00%, Cabbage-Uncooked; Fresh or N/S; Cook Meth N/S 1033000, 211, 5, 0.00%, Potato, tuber, w/o peel-Cooked; Fresh or N/S; Baked 8002720, 150, 1, 0.00%, Pepper, nonbell-Uncooked; Cured etc; Cook Meth N/S15004020, 230, 20, 0.00%, Wheat, flour-Cooked; Dried; Cook Meth N/S15001210, 211, 23, 0.00%, Corn, field, meal-Cooked; Fresh or N/S; Baked 8003750, 240, 9, 0.00%, Tomato-Cooked; Canned; Cook Meth N/S 1033660, 211, 8, 0.00%, Sweet potato-Cooked; Fresh or N/S; Baked95000190, 212, 10, 0.00%, Asparagus-Cooked; Fresh or N/S; Boiled21000470, 212, 16, 0.00%, Beef, fat-Cooked; Fresh or N/S; Boiled95003600, 110, 1, 0.00%, Strawberry, juice-Uncooked; Fresh or N/S; Cook MethN/S19011440, 240, 6, 0.00%, Dillweed-Cooked; Canned; Cook Meth N/S 5010690, 150, 19, 0.00%, Cabbage-Uncooked; Cured etc; Cook Meth N/S 1033000, 210, 3, 0.00%, Potato, tuber, w/o peel-Cooked; Fresh or N/S; CookMeth N/S15004020, 213, 8, 0.00%, Wheat, flour-Cooked; Fresh or N/S; Fried 8002730, 211, 1, 0.00%, Pepper, nonbell, dried-Cooked; Fresh or N/S; Baked

408

25002930, 221, 3, 0.00%, Pork, fat-Cooked; Frozen; Baked27002220, 212, 7, 0.00%, Milk, fat-Cooked; Fresh or N/S; Boiled20003640, 211, 1, 0.00%, Sunflower, seed-Cooked; Fresh or N/S; Baked13010550, 120, 2, 0.00%, Blackberry-Uncooked; Frozen; Cook Meth N/S 8003790, 212, 2, 0.00%, Tomato, juice-Cooked; Fresh or N/S; Boiled 4020860, 240, 4, 0.00%, Celery, juice-Cooked; Canned; Cook Meth N/S 1032990, 211, 2, 0.00%, Potato, tuber, w/peel-Cooked; Fresh or N/S; Baked95001320, 240, 3, 0.00%, Cranberry, juice-Cooked; Canned; Cook Meth N/S25002930, 232, 3, 0.00%, Pork, fat-Cooked; Dried; Boiled15001230, 210, 2, 0.00%, Corn, field, starch-Cooked; Fresh or N/S; Cook MethN/S10001990, 210, 1, 0.00%, Lemon-Cooked; Fresh or N/S; Cook Meth N/S15003240, 232, 4, 0.00%, Rice, brown-Cooked; Dried; Boiled 8003750, 212, 3, 0.00%, Tomato-Cooked; Fresh or N/S; Boiled15004020, 212, 2, 0.00%, Wheat, flour-Cooked; Fresh or N/S; Boiled 2001010, 110, 3, 0.00%, Chicory, tops-Uncooked; Fresh or N/S; Cook Meth N/S 4012480, 110, 2, 0.00%, Parsley, leaves-Uncooked; Fresh or N/S; Cook MethN/S95002810, 211, 2, 0.00%, Pineapple, juice-Cooked; Fresh or N/S; Baked95003590, 211, 2, 0.00%, Strawberry-Cooked; Fresh or N/S; Baked15004010, 211, 5, 0.00%, Wheat, grain-Cooked; Fresh or N/S; Baked95002630, 211, 2, 0.00%, Peanut-Cooked; Fresh or N/S; Baked15001240, 211, 4, 0.00%, Corn, field, syrup-Cooked; Fresh or N/S; Baked 8003750, 210, 4, 0.00%, Tomato-Cooked; Fresh or N/S; Cook Meth N/S15001240, 212, 2, 0.00%, Corn, field, syrup-Cooked; Fresh or N/S; Boiled12000120, 232, 1, 0.00%, Apricot-Cooked; Dried; Boiled 1010780, 110, 1, 0.00%, Carrot-Uncooked; Fresh or N/S; Cook Meth N/S14002690, 211, 1, 0.00%, Pecan-Cooked; Fresh or N/S; Baked23001690, 212, 1, 0.00%, Goat, meat-Cooked; Fresh or N/S; Boiled26003390, 211, 2, 0.00%, Sheep, meat-Cooked; Fresh or N/S; Baked 6003490, 210, 1, 0.00%, Soybean, soy milk-Cooked; Fresh or N/S; Cook MethN/S15004040, 230, 2, 0.00%, Wheat, bran-Cooked; Dried; Cook Meth N/S15001270, 212, 1, 0.00%, Corn, sweet-Cooked; Fresh or N/S; Boiled 8003750, 211, 1, 0.00%, Tomato-Cooked; Fresh or N/S; Baked27002220, 230, 1, 0.00%, Milk, fat-Cooked; Dried; Cook Meth N/S 6030420, 232, 1, 0.00%, Bean, pinto, seed-Cooked; Dried; Boiled15004020, 240, 2, 0.00%, Wheat, flour-Cooked; Canned; Cook Meth N/S 8003760, 212, 2, 0.00%, Tomato, paste-Cooked; Fresh or N/S; Boiled25002920, 213, 1, 0.00%, Pork, meat byproducts-Cooked; Fresh or N/S; Fried25002930, 251, 1, 0.00%, Pork, fat-Cooked; Cured etc; Baked95001300, 240, 1, 0.00%, Cranberry-Cooked; Canned; Cook Meth N/S15001270, 242, 1, 0.00%, Corn, sweet-Cooked; Canned; Boiled95002630, 112, 1, 0.00%, Peanut-Uncooked; Fresh or N/S; Boiled25002920, 210, 1, 0.00%, Pork, meat byproducts-Cooked; Fresh or N/S; CookMeth N/S95002790, 110, 1, 0.00%, Pineapple-Uncooked; Fresh or N/S; Cook Meth N/S 6030360, 232, 1, 0.00%, Bean, kidney, seed-Cooked; Dried; Boiled15004010, 232, 1, 0.00%, Wheat, grain-Cooked; Dried; Boiled20003650, 900, 1, 0.00%, Sunflower, oil-Refined; FF N/A; Cook Meth N/S 5023890, 242, 1, 0.00%, Turnip, greens-Cooked; Canned; Boiled15001220, 230, 1, 0.00%, Corn, field, bran-Cooked; Dried; Cook Meth N/S26003410, 211, 1, 0.00%, Sheep, fat-Cooked; Fresh or N/S; Baked 8003770, 211, 1, 0.00%, Tomato, puree-Cooked; Fresh or N/S; Baked14000810, 211, 1, 0.00%, Cashew-Cooked; Fresh or N/S; Baked11002680, 120, 1, 0.00%, Pear, juice-Uncooked; Frozen; Cook Meth N/S15001210, 213, 1, 0.00%, Corn, field, meal-Cooked; Fresh or N/S; Fried

409

Youth 13-19 yrsLow percentile for CEC records: 95 Exposure (mg/day) = 0.000357High percentile for CEC records: 100 Exposure (mg/day) = 0.026460Number of actual records in this interval: 2203

Critical foods/foodforms for this population (as derived from these records): N=number of appearances in all records (including duplicates) %=percent of total exposure for all records (including duplicates)

Food, FF, N , Percent, Food Name --------, ---, -----, -------, -------------10002000, 110, 576, 11.88%, Lemon, juice-Uncooked; Fresh or N/S; Cook Meth N/S 9010800, 110, 19, 9.48%, Casaba-Uncooked; Fresh or N/S; Cook Meth N/S12000910, 110, 76, 8.39%, Cherry, juice-Uncooked; Fresh or N/S; Cook Meth N/S 5022290, 212, 76, 5.77%, Mustard greens-Cooked; Fresh or N/S; Boiled10001810, 110, 200, 5.60%, Grapefruit, juice-Uncooked; Fresh or N/S; Cook MethN/S 8002720, 110, 140, 5.31%, Pepper, nonbell-Uncooked; Fresh or N/S; Cook MethN/S12002620, 110, 38, 4.49%, Peach, juice-Uncooked; Fresh or N/S; Cook Meth N/S 4023670, 212, 19, 3.94%, Swiss chard-Cooked; Fresh or N/S; Boiled12000910, 210, 194, 3.15%, Cherry, juice-Cooked; Fresh or N/S; Cook Meth N/S 5020700, 210, 57, 2.44%, Cabbage, Chinese, bok choy-Cooked; Fresh or N/S;Cook Meth N/S 8002340, 220, 38, 2.42%, Okra-Cooked; Frozen; Cook Meth N/S 5020700, 150, 57, 2.37%, Cabbage, Chinese, bok choy-Uncooked; Cured etc;Cook Meth N/S11000070, 110, 54, 2.20%, Apple, fruit with peel-Uncooked; Fresh or N/S; CookMeth N/S95002810, 110, 129, 1.86%, Pineapple, juice-Uncooked; Fresh or N/S; Cook MethN/S11000090, 211, 122, 1.58%, Apple, dried-Cooked; Fresh or N/S; Baked 8002720, 210, 178, 1.42%, Pepper, nonbell-Cooked; Fresh or N/S; Cook Meth N/S 4023220, 211, 19, 1.33%, Rhubarb-Cooked; Fresh or N/S; Baked 8002720, 212, 77, 1.31%, Pepper, nonbell-Cooked; Fresh or N/S; Boiled95002350, 240, 13, 1.12%, Olive-Cooked; Canned; Cook Meth N/S13020570, 211, 33, 1.12%, Blueberry-Cooked; Fresh or N/S; Baked10003690, 110, 61, 0.95%, Tangerine-Uncooked; Fresh or N/S; Cook Meth N/S 8002720, 150, 58, 0.81%, Pepper, nonbell-Uncooked; Cured etc; Cook Meth N/S 8002340, 213, 38, 0.74%, Okra-Cooked; Fresh or N/S; Fried10002000, 210, 194, 0.71%, Lemon, juice-Cooked; Fresh or N/S; Cook Meth N/S25002930, 210, 449, 0.70%, Pork, fat-Cooked; Fresh or N/S; Cook Meth N/S 8002720, 220, 19, 0.69%, Pepper, nonbell-Cooked; Frozen; Cook Meth N/S13010580, 240, 147, 0.63%, Boysenberry-Cooked; Canned; Cook Meth N/S95001750, 110, 17, 0.57%, Grape-Uncooked; Fresh or N/S; Cook Meth N/S12000910, 240, 141, 0.54%, Cherry, juice-Cooked; Canned; Cook Meth N/S95002350, 211, 13, 0.52%, Olive-Cooked; Fresh or N/S; Baked10003700, 240, 163, 0.52%, Tangerine, juice-Cooked; Canned; Cook Meth N/S11000090, 230, 22, 0.49%, Apple, dried-Cooked; Dried; Cook Meth N/S15001240, 240, 727, 0.47%, Corn, field, syrup-Cooked; Canned; Cook Meth N/S10002000, 240, 165, 0.45%, Lemon, juice-Cooked; Canned; Cook Meth N/S 8002340, 210, 19, 0.45%, Okra-Cooked; Fresh or N/S; Cook Meth N/S10001810, 240, 180, 0.44%, Grapefruit, juice-Cooked; Canned; Cook Meth N/S13010550, 211, 4, 0.43%, Blackberry-Cooked; Fresh or N/S; Baked13013200, 240, 22, 0.40%, Raspberry-Cooked; Canned; Cook Meth N/S10002070, 240, 162, 0.40%, Lime, juice-Cooked; Canned; Cook Meth N/S10002070, 110, 38, 0.39%, Lime, juice-Uncooked; Fresh or N/S; Cook Meth N/S 9020880, 210, 19, 0.38%, Chayote, fruit-Cooked; Fresh or N/S; Cook Meth N/S 8002720, 240, 140, 0.33%, Pepper, nonbell-Cooked; Canned; Cook Meth N/S12000900, 110, 2, 0.30%, Cherry-Uncooked; Fresh or N/S; Cook Meth N/S13010550, 240, 32, 0.28%, Blackberry-Cooked; Canned; Cook Meth N/S10002410, 110, 256, 0.25%, Orange, juice-Uncooked; Fresh or N/S; Cook Meth N/S10002000, 130, 23, 0.25%, Lemon, juice-Uncooked; Dried; Cook Meth N/S 8002700, 110, 17, 0.22%, Pepper, bell-Uncooked; Fresh or N/S; Cook Meth N/S

410

11000100, 110, 114, 0.22%, Apple, juice-Uncooked; Fresh or N/S; Cook Meth N/S13013210, 110, 10, 0.22%, Raspberry, juice-Uncooked; Fresh or N/S; Cook MethN/S12002600, 240, 18, 0.22%, Peach-Cooked; Canned; Cook Meth N/S95003590, 110, 6, 0.20%, Strawberry-Uncooked; Fresh or N/S; Cook Meth N/S13020570, 110, 6, 0.20%, Blueberry-Uncooked; Fresh or N/S; Cook Meth N/S25002930, 213, 121, 0.19%, Pork, fat-Cooked; Fresh or N/S; Fried25002930, 211, 182, 0.19%, Pork, fat-Cooked; Fresh or N/S; Baked15001240, 110, 390, 0.18%, Corn, field, syrup-Uncooked; Fresh or N/S; CookMeth N/S27002220, 110, 349, 0.16%, Milk, fat-Uncooked; Fresh or N/S; Cook Meth N/S 8002340, 240, 11, 0.16%, Okra-Cooked; Canned; Cook Meth N/S12002600, 110, 7, 0.15%, Peach-Uncooked; Fresh or N/S; Cook Meth N/S 8002730, 211, 19, 0.15%, Pepper, nonbell, dried-Cooked; Fresh or N/S; Baked95002810, 240, 141, 0.14%, Pineapple, juice-Cooked; Canned; Cook Meth N/S15004020, 211, 368, 0.13%, Wheat, flour-Cooked; Fresh or N/S; Baked25002930, 250, 158, 0.13%, Pork, fat-Cooked; Cured etc; Cook Meth N/S25002900, 210, 138, 0.13%, Pork, meat-Cooked; Fresh or N/S; Cook Meth N/S15003250, 230, 62, 0.12%, Rice, flour-Cooked; Dried; Cook Meth N/S13010580, 110, 19, 0.12%, Boysenberry-Uncooked; Fresh or N/S; Cook Meth N/S10001990, 110, 29, 0.12%, Lemon-Uncooked; Fresh or N/S; Cook Meth N/S12002300, 110, 1, 0.11%, Nectarine-Uncooked; Fresh or N/S; Cook Meth N/S 8003770, 210, 88, 0.11%, Tomato, puree-Cooked; Fresh or N/S; Cook Meth N/S 8002730, 210, 87, 0.10%, Pepper, nonbell, dried-Cooked; Fresh or N/S; CookMeth N/S 8002700, 210, 8, 0.10%, Pepper, bell-Cooked; Fresh or N/S; Cook Meth N/S21000440, 211, 125, 0.10%, Beef, meat-Cooked; Fresh or N/S; Baked12000900, 211, 3, 0.10%, Cherry-Cooked; Fresh or N/S; Baked25002930, 253, 63, 0.10%, Pork, fat-Cooked; Cured etc; Fried11000080, 211, 3, 0.09%, Apple, peeled fruit-Cooked; Fresh or N/S; Baked 8002730, 212, 27, 0.08%, Pepper, nonbell, dried-Cooked; Fresh or N/S; Boiled13020570, 214, 2, 0.08%, Blueberry-Cooked; Fresh or N/S; Fried/baked15004020, 232, 57, 0.08%, Wheat, flour-Cooked; Dried; Boiled10002000, 211, 61, 0.07%, Lemon, juice-Cooked; Fresh or N/S; Baked10002410, 120, 105, 0.07%, Orange, juice-Uncooked; Frozen; Cook Meth N/S11002660, 110, 2, 0.07%, Pear-Uncooked; Fresh or N/S; Cook Meth N/S95003590, 240, 1, 0.07%, Strawberry-Cooked; Canned; Cook Meth N/S10003700, 110, 19, 0.06%, Tangerine, juice-Uncooked; Fresh or N/S; Cook MethN/S13010580, 120, 58, 0.06%, Boysenberry-Uncooked; Frozen; Cook Meth N/S15001210, 233, 103, 0.06%, Corn, field, meal-Cooked; Dried; Fried95001750, 210, 9, 0.06%, Grape-Cooked; Fresh or N/S; Cook Meth N/S25002900, 211, 68, 0.06%, Pork, meat-Cooked; Fresh or N/S; Baked13020570, 210, 2, 0.06%, Blueberry-Cooked; Fresh or N/S; Cook Meth N/S 8002700, 211, 9, 0.06%, Pepper, bell-Cooked; Fresh or N/S; Baked10002070, 120, 56, 0.06%, Lime, juice-Uncooked; Frozen; Cook Meth N/S 8002700, 213, 6, 0.06%, Pepper, bell-Cooked; Fresh or N/S; Fried21000440, 210, 137, 0.05%, Beef, meat-Cooked; Fresh or N/S; Cook Meth N/S25002900, 250, 102, 0.05%, Pork, meat-Cooked; Cured etc; Cook Meth N/S95001760, 110, 31, 0.05%, Grape, juice-Uncooked; Fresh or N/S; Cook Meth N/S25002930, 230, 42, 0.05%, Pork, fat-Cooked; Dried; Cook Meth N/S21000470, 210, 115, 0.04%, Beef, fat-Cooked; Fresh or N/S; Cook Meth N/S21000470, 211, 53, 0.04%, Beef, fat-Cooked; Fresh or N/S; Baked13020570, 213, 2, 0.04%, Blueberry-Cooked; Fresh or N/S; Fried21000440, 213, 123, 0.04%, Beef, meat-Cooked; Fresh or N/S; Fried21000470, 213, 122, 0.04%, Beef, fat-Cooked; Fresh or N/S; Fried11002660, 240, 2, 0.04%, Pear-Cooked; Canned; Cook Meth N/S20003640, 211, 19, 0.03%, Sunflower, seed-Cooked; Fresh or N/S; Baked 8002730, 240, 59, 0.03%, Pepper, nonbell, dried-Cooked; Canned; Cook MethN/S10003700, 120, 57, 0.03%, Tangerine, juice-Uncooked; Frozen; Cook Meth N/S11000070, 211, 1, 0.03%, Apple, fruit with peel-Cooked; Fresh or N/S; Baked15001200, 214, 78, 0.03%, Corn, field, flour-Cooked; Fresh or N/S;Fried/baked 8003760, 210, 21, 0.03%, Tomato, paste-Cooked; Fresh or N/S; Cook Meth N/S

411

15001200, 230, 73, 0.03%, Corn, field, flour-Cooked; Dried; Cook Meth N/S21000440, 212, 55, 0.03%, Beef, meat-Cooked; Fresh or N/S; Boiled27002220, 120, 45, 0.03%, Milk, fat-Uncooked; Frozen; Cook Meth N/S 9021350, 110, 22, 0.03%, Cucumber-Uncooked; Fresh or N/S; Cook Meth N/S10002000, 120, 57, 0.03%, Lemon, juice-Uncooked; Frozen; Cook Meth N/S25002900, 213, 57, 0.02%, Pork, meat-Cooked; Fresh or N/S; Fried15001210, 230, 60, 0.02%, Corn, field, meal-Cooked; Dried; Cook Meth N/S 8002720, 215, 19, 0.02%, Pepper, nonbell-Cooked; Fresh or N/S; Boiled/baked13013210, 240, 11, 0.02%, Raspberry, juice-Cooked; Canned; Cook Meth N/S95001760, 240, 41, 0.02%, Grape, juice-Cooked; Canned; Cook Meth N/S 9010750, 110, 2, 0.02%, Cantaloupe-Uncooked; Fresh or N/S; Cook Meth N/S23001690, 212, 19, 0.02%, Goat, meat-Cooked; Fresh or N/S; Boiled95003600, 110, 2, 0.02%, Strawberry, juice-Uncooked; Fresh or N/S; Cook MethN/S15001240, 130, 44, 0.02%, Corn, field, syrup-Uncooked; Dried; Cook Meth N/S15004020, 210, 63, 0.02%, Wheat, flour-Cooked; Fresh or N/S; Cook Meth N/S 6010430, 242, 1, 0.02%, Bean, snap, succulent-Cooked; Canned; Boiled 6010430, 222, 1, 0.02%, Bean, snap, succulent-Cooked; Frozen; Boiled 4012480, 210, 41, 0.02%, Parsley, leaves-Cooked; Fresh or N/S; Cook Meth N/S13013200, 211, 6, 0.02%, Raspberry-Cooked; Fresh or N/S; Baked10002400, 110, 2, 0.02%, Orange-Uncooked; Fresh or N/S; Cook Meth N/S 8002700, 150, 7, 0.02%, Pepper, bell-Uncooked; Cured etc; Cook Meth N/S27002220, 232, 19, 0.02%, Milk, fat-Cooked; Dried; Boiled25002930, 212, 42, 0.02%, Pork, fat-Cooked; Fresh or N/S; Boiled 8002720, 213, 21, 0.02%, Pepper, nonbell-Cooked; Fresh or N/S; Fried95001750, 240, 2, 0.02%, Grape-Cooked; Canned; Cook Meth N/S15001240, 120, 40, 0.02%, Corn, field, syrup-Uncooked; Frozen; Cook Meth N/S11000080, 110, 1, 0.02%, Apple, peeled fruit-Uncooked; Fresh or N/S; CookMeth N/S 1010790, 110, 9, 0.02%, Carrot, juice-Uncooked; Fresh or N/S; Cook Meth N/S12000120, 240, 7, 0.02%, Apricot-Cooked; Canned; Cook Meth N/S12000910, 120, 38, 0.02%, Cherry, juice-Uncooked; Frozen; Cook Meth N/S15001260, 230, 50, 0.01%, Corn, pop-Cooked; Dried; Cook Meth N/S21000470, 212, 19, 0.01%, Beef, fat-Cooked; Fresh or N/S; Boiled15003250, 210, 25, 0.01%, Rice, flour-Cooked; Fresh or N/S; Cook Meth N/S14000810, 211, 19, 0.01%, Cashew-Cooked; Fresh or N/S; Baked15001200, 210, 41, 0.01%, Corn, field, flour-Cooked; Fresh or N/S; Cook MethN/S21000440, 250, 19, 0.01%, Beef, meat-Cooked; Cured etc; Cook Meth N/S13020570, 240, 6, 0.01%, Blueberry-Cooked; Canned; Cook Meth N/S95003600, 210, 2, 0.01%, Strawberry, juice-Cooked; Fresh or N/S; Cook MethN/S 8002720, 232, 20, 0.01%, Pepper, nonbell-Cooked; Dried; Boiled21000470, 250, 19, 0.01%, Beef, fat-Cooked; Cured etc; Cook Meth N/S95002640, 210, 35, 0.01%, Peanut, butter-Cooked; Fresh or N/S; Cook Meth N/S 8003770, 240, 21, 0.01%, Tomato, puree-Cooked; Canned; Cook Meth N/S95002350, 232, 1, 0.01%, Olive-Cooked; Dried; Boiled 8002720, 211, 21, 0.01%, Pepper, nonbell-Cooked; Fresh or N/S; Baked25002930, 251, 19, 0.01%, Pork, fat-Cooked; Cured etc; Baked26003390, 210, 19, 0.01%, Sheep, meat-Cooked; Fresh or N/S; Cook Meth N/S 1033000, 212, 5, 0.01%, Potato, tuber, w/o peel-Cooked; Fresh or N/S;Boiled11000110, 212, 10, 0.01%, Apple, sauce-Cooked; Fresh or N/S; Boiled15001200, 211, 19, 0.01%, Corn, field, flour-Cooked; Fresh or N/S; Baked25002930, 232, 19, 0.01%, Pork, fat-Cooked; Dried; Boiled 6030980, 232, 19, 0.01%, Chickpea, seed-Cooked; Dried; Boiled25002900, 251, 19, 0.01%, Pork, meat-Cooked; Cured etc; Baked15004020, 212, 19, 0.01%, Wheat, flour-Cooked; Fresh or N/S; Boiled15004010, 211, 10, 0.01%, Wheat, grain-Cooked; Fresh or N/S; Baked 6010430, 212, 1, 0.01%, Bean, snap, succulent-Cooked; Fresh or N/S; Boiled95002790, 240, 2, 0.01%, Pineapple-Cooked; Canned; Cook Meth N/S95001320, 240, 9, 0.01%, Cranberry, juice-Cooked; Canned; Cook Meth N/S27002220, 211, 13, 0.01%, Milk, fat-Cooked; Fresh or N/S; Baked10002410, 240, 14, 0.01%, Orange, juice-Cooked; Canned; Cook Meth N/S 8002730, 213, 23, 0.01%, Pepper, nonbell, dried-Cooked; Fresh or N/S; Fried

412

8002720, 250, 19, 0.01%, Pepper, nonbell-Cooked; Cured etc; Cook Meth N/S 8003760, 212, 19, 0.01%, Tomato, paste-Cooked; Fresh or N/S; Boiled15004020, 213, 20, 0.01%, Wheat, flour-Cooked; Fresh or N/S; Fried 8002700, 212, 2, 0.01%, Pepper, bell-Cooked; Fresh or N/S; Boiled21000440, 221, 19, 0.01%, Beef, meat-Cooked; Frozen; Baked27002220, 214, 19, 0.01%, Milk, fat-Cooked; Fresh or N/S; Fried/baked13013200, 110, 2, 0.00%, Raspberry-Uncooked; Fresh or N/S; Cook Meth N/S 9021350, 240, 6, 0.00%, Cucumber-Cooked; Canned; Cook Meth N/S15004020, 231, 21, 0.00%, Wheat, flour-Cooked; Dried; Baked25002900, 253, 19, 0.00%, Pork, meat-Cooked; Cured etc; Fried15004020, 221, 18, 0.00%, Wheat, flour-Cooked; Frozen; Baked12000140, 240, 2, 0.00%, Apricot, juice-Cooked; Canned; Cook Meth N/S 6030410, 232, 19, 0.00%, Bean, pink, seed-Cooked; Dried; Boiled26003410, 210, 19, 0.00%, Sheep, fat-Cooked; Fresh or N/S; Cook Meth N/S95000230, 110, 14, 0.00%, Banana-Uncooked; Fresh or N/S; Cook Meth N/S 1032990, 212, 3, 0.00%, Potato, tuber, w/peel-Cooked; Fresh or N/S; Boiled 6030420, 232, 19, 0.00%, Bean, pinto, seed-Cooked; Dried; Boiled95003590, 211, 2, 0.00%, Strawberry-Cooked; Fresh or N/S; Baked15001240, 210, 17, 0.00%, Corn, field, syrup-Cooked; Fresh or N/S; Cook MethN/S11002660, 210, 3, 0.00%, Pear-Cooked; Fresh or N/S; Cook Meth N/S27002220, 210, 12, 0.00%, Milk, fat-Cooked; Fresh or N/S; Cook Meth N/S95002360, 900, 4, 0.00%, Olive, oil-Refined; FF N/A; Cook Meth N/S13013200, 120, 1, 0.00%, Raspberry-Uncooked; Frozen; Cook Meth N/S11000100, 210, 9, 0.00%, Apple, juice-Cooked; Fresh or N/S; Cook Meth N/S95003600, 240, 2, 0.00%, Strawberry, juice-Cooked; Canned; Cook Meth N/S 8003750, 211, 5, 0.00%, Tomato-Cooked; Fresh or N/S; Baked11000100, 240, 4, 0.00%, Apple, juice-Cooked; Canned; Cook Meth N/S12002600, 211, 1, 0.00%, Peach-Cooked; Fresh or N/S; Baked11002680, 240, 3, 0.00%, Pear, juice-Cooked; Canned; Cook Meth N/S 8002700, 221, 1, 0.00%, Pepper, bell-Cooked; Frozen; Baked 1033000, 210, 3, 0.00%, Potato, tuber, w/o peel-Cooked; Fresh or N/S; CookMeth N/S 8003750, 240, 4, 0.00%, Tomato-Cooked; Canned; Cook Meth N/S 8003790, 240, 2, 0.00%, Tomato, juice-Cooked; Canned; Cook Meth N/S 8003760, 211, 8, 0.00%, Tomato, paste-Cooked; Fresh or N/S; Baked15001210, 211, 4, 0.00%, Corn, field, meal-Cooked; Fresh or N/S; Baked12000130, 211, 2, 0.00%, Apricot, dried-Cooked; Fresh or N/S; Baked13013210, 120, 2, 0.00%, Raspberry, juice-Uncooked; Frozen; Cook Meth N/S95001760, 210, 3, 0.00%, Grape, juice-Cooked; Fresh or N/S; Cook Meth N/S11002680, 110, 1, 0.00%, Pear, juice-Uncooked; Fresh or N/S; Cook Meth N/S 1032990, 211, 2, 0.00%, Potato, tuber, w/peel-Cooked; Fresh or N/S; Baked 8003750, 215, 2, 0.00%, Tomato-Cooked; Fresh or N/S; Boiled/baked13010550, 120, 2, 0.00%, Blackberry-Uncooked; Frozen; Cook Meth N/S21000450, 232, 1, 0.00%, Beef, meat, dried-Cooked; Dried; Boiled13020570, 120, 1, 0.00%, Blueberry-Uncooked; Frozen; Cook Meth N/S95002630, 112, 1, 0.00%, Peanut-Uncooked; Fresh or N/S; Boiled10001800, 110, 1, 0.00%, Grapefruit-Uncooked; Fresh or N/S; Cook Meth N/S12000900, 240, 1, 0.00%, Cherry-Cooked; Canned; Cook Meth N/S 8003750, 212, 2, 0.00%, Tomato-Cooked; Fresh or N/S; Boiled15001260, 231, 3, 0.00%, Corn, pop-Cooked; Dried; Baked27002220, 212, 3, 0.00%, Milk, fat-Cooked; Fresh or N/S; Boiled 8003770, 211, 2, 0.00%, Tomato, puree-Cooked; Fresh or N/S; Baked 8002700, 215, 1, 0.00%, Pepper, bell-Cooked; Fresh or N/S; Boiled/baked 8003750, 110, 3, 0.00%, Tomato-Uncooked; Fresh or N/S; Cook Meth N/S 4020860, 240, 2, 0.00%, Celery, juice-Cooked; Canned; Cook Meth N/S 6003470, 210, 1, 0.00%, Soybean, seed-Cooked; Fresh or N/S; Cook Meth N/S15004010, 232, 2, 0.00%, Wheat, grain-Cooked; Dried; Boiled 1033000, 211, 1, 0.00%, Potato, tuber, w/o peel-Cooked; Fresh or N/S; Baked25002900, 212, 1, 0.00%, Pork, meat-Cooked; Fresh or N/S; Boiled15003250, 211, 1, 0.00%, Rice, flour-Cooked; Fresh or N/S; Baked 8002720, 221, 1, 0.00%, Pepper, nonbell-Cooked; Frozen; Baked27002220, 230, 1, 0.00%, Milk, fat-Cooked; Dried; Cook Meth N/S12000900, 120, 1, 0.00%, Cherry-Uncooked; Frozen; Cook Meth N/S15004020, 214, 1, 0.00%, Wheat, flour-Cooked; Fresh or N/S; Fried/baked

413

8003750, 210, 1, 0.00%, Tomato-Cooked; Fresh or N/S; Cook Meth N/S25002930, 222, 1, 0.00%, Pork, fat-Cooked; Frozen; Boiled95002790, 110, 1, 0.00%, Pineapple-Uncooked; Fresh or N/S; Cook Meth N/S15004010, 230, 1, 0.00%, Wheat, grain-Cooked; Dried; Cook Meth N/S

414

Adults 20-49 yrsLow percentile for CEC records: 95 Exposure (mg/day) = 0.000345High percentile for CEC records: 100 Exposure (mg/day) = 0.037797Number of actual records in this interval: 8813

Critical foods/foodforms for this population (as derived from these records): N=number of appearances in all records (including duplicates) %=percent of total exposure for all records (including duplicates)

Food, FF, N , Percent, Food Name --------, ---, -----, -------, ------------- 8002720, 110, 1697, 13.10%, Pepper, nonbell-Uncooked; Fresh or N/S; Cook MethN/S 5022290, 212, 269, 7.05%, Mustard greens-Cooked; Fresh or N/S; Boiled10002000, 110, 1522, 6.19%, Lemon, juice-Uncooked; Fresh or N/S; Cook Meth N/S 5020700, 150, 361, 5.31%, Cabbage, Chinese, bok choy-Uncooked; Cured etc;Cook Meth N/S12002880, 110, 173, 5.06%, Plum, prune, juice-Uncooked; Fresh or N/S; CookMeth N/S 4023220, 211, 133, 4.10%, Rhubarb-Cooked; Fresh or N/S; Baked10001810, 110, 840, 3.82%, Grapefruit, juice-Uncooked; Fresh or N/S; Cook MethN/S 8002720, 210, 983, 3.59%, Pepper, nonbell-Cooked; Fresh or N/S; Cook Meth N/S 4023220, 240, 19, 3.14%, Rhubarb-Cooked; Canned; Cook Meth N/S 5020700, 210, 254, 2.60%, Cabbage, Chinese, bok choy-Cooked; Fresh or N/S;Cook Meth N/S95002810, 110, 498, 2.48%, Pineapple, juice-Uncooked; Fresh or N/S; Cook MethN/S 8002720, 213, 404, 2.45%, Pepper, nonbell-Cooked; Fresh or N/S; Fried 8002340, 210, 306, 2.40%, Okra-Cooked; Fresh or N/S; Cook Meth N/S12002620, 110, 133, 2.14%, Peach, juice-Uncooked; Fresh or N/S; Cook Meth N/S10002070, 110, 535, 2.05%, Lime, juice-Uncooked; Fresh or N/S; Cook Meth N/S13020570, 110, 51, 1.77%, Blueberry-Uncooked; Fresh or N/S; Cook Meth N/S 8002720, 240, 698, 1.50%, Pepper, nonbell-Cooked; Canned; Cook Meth N/S12002620, 240, 114, 1.36%, Peach, juice-Cooked; Canned; Cook Meth N/S11000070, 110, 178, 1.25%, Apple, fruit with peel-Uncooked; Fresh or N/S; CookMeth N/S95002350, 240, 72, 1.11%, Olive-Cooked; Canned; Cook Meth N/S 8002720, 150, 326, 1.04%, Pepper, nonbell-Uncooked; Cured etc; Cook Meth N/S 8002720, 212, 285, 1.01%, Pepper, nonbell-Cooked; Fresh or N/S; Boiled13020570, 211, 91, 0.99%, Blueberry-Cooked; Fresh or N/S; Baked 8002340, 220, 95, 0.91%, Okra-Cooked; Frozen; Cook Meth N/S 5022290, 242, 19, 0.91%, Mustard greens-Cooked; Canned; Boiled10002000, 240, 522, 0.76%, Lemon, juice-Cooked; Canned; Cook Meth N/S 5022290, 222, 19, 0.73%, Mustard greens-Cooked; Frozen; Boiled 8002340, 213, 155, 0.73%, Okra-Cooked; Fresh or N/S; Fried12002610, 130, 114, 0.72%, Peach, dried-Uncooked; Dried; Cook Meth N/S12000910, 110, 114, 0.69%, Cherry, juice-Uncooked; Fresh or N/S; Cook Meth N/S 8002700, 210, 150, 0.69%, Pepper, bell-Cooked; Fresh or N/S; Cook Meth N/S13013200, 240, 95, 0.68%, Raspberry-Cooked; Canned; Cook Meth N/S13010580, 110, 95, 0.66%, Boysenberry-Uncooked; Fresh or N/S; Cook Meth N/S10003690, 110, 188, 0.56%, Tangerine-Uncooked; Fresh or N/S; Cook Meth N/S 8002700, 110, 136, 0.56%, Pepper, bell-Uncooked; Fresh or N/S; Cook Meth N/S13010580, 120, 105, 0.56%, Boysenberry-Uncooked; Frozen; Cook Meth N/S95001750, 110, 72, 0.53%, Grape-Uncooked; Fresh or N/S; Cook Meth N/S10001810, 240, 345, 0.49%, Grapefruit, juice-Cooked; Canned; Cook Meth N/S 4020860, 110, 19, 0.44%, Celery, juice-Uncooked; Fresh or N/S; Cook Meth N/S10001810, 120, 137, 0.39%, Grapefruit, juice-Uncooked; Frozen; Cook Meth N/S11000090, 211, 192, 0.39%, Apple, dried-Cooked; Fresh or N/S; Baked13013200, 110, 30, 0.35%, Raspberry-Uncooked; Fresh or N/S; Cook Meth N/S95002350, 211, 54, 0.34%, Olive-Cooked; Fresh or N/S; Baked 4023670, 212, 19, 0.33%, Swiss chard-Cooked; Fresh or N/S; Boiled12002300, 110, 31, 0.31%, Nectarine-Uncooked; Fresh or N/S; Cook Meth N/S12002600, 110, 51, 0.30%, Peach-Uncooked; Fresh or N/S; Cook Meth N/S

415

13021360, 110, 38, 0.30%, Currant-Uncooked; Fresh or N/S; Cook Meth N/S10003700, 110, 133, 0.28%, Tangerine, juice-Uncooked; Fresh or N/S; Cook MethN/S11000090, 130, 133, 0.27%, Apple, dried-Uncooked; Dried; Cook Meth N/S10002000, 130, 122, 0.27%, Lemon, juice-Uncooked; Dried; Cook Meth N/S10003700, 240, 326, 0.26%, Tangerine, juice-Cooked; Canned; Cook Meth N/S25002930, 210, 1086, 0.25%, Pork, fat-Cooked; Fresh or N/S; Cook Meth N/S 9020880, 210, 38, 0.22%, Chayote, fruit-Cooked; Fresh or N/S; Cook Meth N/S10002070, 240, 304, 0.21%, Lime, juice-Cooked; Canned; Cook Meth N/S11002660, 110, 38, 0.19%, Pear-Uncooked; Fresh or N/S; Cook Meth N/S11002670, 130, 114, 0.18%, Pear, dried-Uncooked; Dried; Cook Meth N/S12002610, 230, 38, 0.18%, Peach, dried-Cooked; Dried; Cook Meth N/S10001990, 110, 314, 0.17%, Lemon-Uncooked; Fresh or N/S; Cook Meth N/S25002930, 230, 495, 0.16%, Pork, fat-Cooked; Dried; Cook Meth N/S15001240, 240, 1466, 0.16%, Corn, field, syrup-Cooked; Canned; Cook Meth N/S 8002340, 240, 19, 0.15%, Okra-Cooked; Canned; Cook Meth N/S95003590, 110, 31, 0.14%, Strawberry-Uncooked; Fresh or N/S; Cook Meth N/S 8002720, 221, 25, 0.14%, Pepper, nonbell-Cooked; Frozen; Baked 5020700, 110, 19, 0.14%, Cabbage, Chinese, bok choy-Uncooked; Fresh or N/S;Cook Meth N/S13010550, 240, 54, 0.14%, Blackberry-Cooked; Canned; Cook Meth N/S10002060, 110, 79, 0.13%, Lime-Uncooked; Fresh or N/S; Cook Meth N/S 8002720, 220, 38, 0.13%, Pepper, nonbell-Cooked; Frozen; Cook Meth N/S12002600, 240, 27, 0.13%, Peach-Cooked; Canned; Cook Meth N/S25002930, 213, 429, 0.12%, Pork, fat-Cooked; Fresh or N/S; Fried25002930, 211, 487, 0.11%, Pork, fat-Cooked; Fresh or N/S; Baked13020570, 240, 11, 0.11%, Blueberry-Cooked; Canned; Cook Meth N/S11000080, 211, 13, 0.11%, Apple, peeled fruit-Cooked; Fresh or N/S; Baked 8002730, 211, 84, 0.10%, Pepper, nonbell, dried-Cooked; Fresh or N/S; Baked10002000, 211, 293, 0.10%, Lemon, juice-Cooked; Fresh or N/S; Baked95002810, 240, 99, 0.10%, Pineapple, juice-Cooked; Canned; Cook Meth N/S 9020210, 212, 19, 0.10%, Balsam pear-Cooked; Fresh or N/S; Boiled95002360, 900, 271, 0.09%, Olive, oil-Refined; FF N/A; Cook Meth N/S12000900, 110, 25, 0.09%, Cherry-Uncooked; Fresh or N/S; Cook Meth N/S13020570, 214, 5, 0.09%, Blueberry-Cooked; Fresh or N/S; Fried/baked25002930, 253, 258, 0.09%, Pork, fat-Cooked; Cured etc; Fried 2001400, 212, 19, 0.09%, Dasheen, leaves-Cooked; Fresh or N/S; Boiled95002800, 130, 114, 0.08%, Pineapple, dried-Uncooked; Dried; Cook Meth N/S25002930, 250, 481, 0.08%, Pork, fat-Cooked; Cured etc; Cook Meth N/S 6010430, 242, 15, 0.08%, Bean, snap, succulent-Cooked; Canned; Boiled10002410, 110, 414, 0.08%, Orange, juice-Uncooked; Fresh or N/S; Cook Meth N/S15001240, 110, 728, 0.08%, Corn, field, syrup-Uncooked; Fresh or N/S; CookMeth N/S13020570, 120, 13, 0.08%, Blueberry-Uncooked; Frozen; Cook Meth N/S 8002730, 212, 186, 0.07%, Pepper, nonbell, dried-Cooked; Fresh or N/S; Boiled10002000, 210, 87, 0.07%, Lemon, juice-Cooked; Fresh or N/S; Cook Meth N/S10001070, 110, 19, 0.07%, Citrus hybrids-Uncooked; Fresh or N/S; Cook MethN/S 4011500, 110, 189, 0.07%, Endive-Uncooked; Fresh or N/S; Cook Meth N/S 8002700, 213, 25, 0.07%, Pepper, bell-Cooked; Fresh or N/S; Fried12000900, 211, 15, 0.06%, Cherry-Cooked; Fresh or N/S; Baked15004020, 211, 684, 0.06%, Wheat, flour-Cooked; Fresh or N/S; Baked10002070, 120, 127, 0.06%, Lime, juice-Uncooked; Frozen; Cook Meth N/S13010550, 110, 11, 0.06%, Blackberry-Uncooked; Fresh or N/S; Cook Meth N/S13013200, 120, 10, 0.06%, Raspberry-Uncooked; Frozen; Cook Meth N/S11000100, 110, 107, 0.06%, Apple, juice-Uncooked; Fresh or N/S; Cook Meth N/S15001200, 214, 410, 0.06%, Corn, field, flour-Cooked; Fresh or N/S;Fried/baked95000730, 110, 57, 0.06%, Cactus-Uncooked; Fresh or N/S; Cook Meth N/S10003700, 120, 84, 0.05%, Tangerine, juice-Uncooked; Frozen; Cook Meth N/S10002000, 120, 86, 0.05%, Lemon, juice-Uncooked; Frozen; Cook Meth N/S13010580, 240, 157, 0.05%, Boysenberry-Cooked; Canned; Cook Meth N/S13020570, 213, 9, 0.05%, Blueberry-Cooked; Fresh or N/S; Fried21000440, 210, 428, 0.04%, Beef, meat-Cooked; Fresh or N/S; Cook Meth N/S

416

13013210, 110, 10, 0.04%, Raspberry, juice-Uncooked; Fresh or N/S; Cook MethN/S12002600, 211, 7, 0.04%, Peach-Cooked; Fresh or N/S; Baked25002900, 250, 268, 0.04%, Pork, meat-Cooked; Cured etc; Cook Meth N/S25002930, 232, 119, 0.04%, Pork, fat-Cooked; Dried; Boiled 8002720, 211, 109, 0.04%, Pepper, nonbell-Cooked; Fresh or N/S; Baked27002220, 110, 405, 0.04%, Milk, fat-Uncooked; Fresh or N/S; Cook Meth N/S95001760, 110, 81, 0.04%, Grape, juice-Uncooked; Fresh or N/S; Cook Meth N/S 6010430, 212, 8, 0.04%, Bean, snap, succulent-Cooked; Fresh or N/S; Boiled10002410, 120, 192, 0.04%, Orange, juice-Uncooked; Frozen; Cook Meth N/S10002000, 212, 40, 0.04%, Lemon, juice-Cooked; Fresh or N/S; Boiled13010550, 120, 6, 0.04%, Blackberry-Uncooked; Frozen; Cook Meth N/S13013200, 211, 14, 0.04%, Raspberry-Cooked; Fresh or N/S; Baked 8002720, 230, 76, 0.03%, Pepper, nonbell-Cooked; Dried; Cook Meth N/S21000440, 211, 241, 0.03%, Beef, meat-Cooked; Fresh or N/S; Baked12000910, 120, 84, 0.03%, Cherry, juice-Uncooked; Frozen; Cook Meth N/S95002810, 120, 99, 0.03%, Pineapple, juice-Uncooked; Frozen; Cook Meth N/S25002900, 210, 248, 0.03%, Pork, meat-Cooked; Fresh or N/S; Cook Meth N/S 9010750, 110, 18, 0.03%, Cantaloupe-Uncooked; Fresh or N/S; Cook Meth N/S25002900, 211, 165, 0.03%, Pork, meat-Cooked; Fresh or N/S; Baked21000470, 210, 269, 0.03%, Beef, fat-Cooked; Fresh or N/S; Cook Meth N/S13020570, 210, 5, 0.03%, Blueberry-Cooked; Fresh or N/S; Cook Meth N/S21000470, 213, 237, 0.03%, Beef, fat-Cooked; Fresh or N/S; Fried21000440, 213, 281, 0.03%, Beef, meat-Cooked; Fresh or N/S; Fried 9021350, 110, 58, 0.03%, Cucumber-Uncooked; Fresh or N/S; Cook Meth N/S12000120, 110, 5, 0.02%, Apricot-Uncooked; Fresh or N/S; Cook Meth N/S 8002700, 211, 37, 0.02%, Pepper, bell-Cooked; Fresh or N/S; Baked10002400, 110, 13, 0.02%, Orange-Uncooked; Fresh or N/S; Cook Meth N/S 8002700, 150, 21, 0.02%, Pepper, bell-Uncooked; Cured etc; Cook Meth N/S 8002340, 242, 19, 0.02%, Okra-Cooked; Canned; Boiled 2001010, 110, 159, 0.02%, Chicory, tops-Uncooked; Fresh or N/S; Cook Meth N/S95003590, 240, 11, 0.02%, Strawberry-Cooked; Canned; Cook Meth N/S25002900, 213, 128, 0.02%, Pork, meat-Cooked; Fresh or N/S; Fried 8002730, 210, 141, 0.02%, Pepper, nonbell, dried-Cooked; Fresh or N/S; CookMeth N/S95003600, 240, 9, 0.02%, Strawberry, juice-Cooked; Canned; Cook Meth N/S 8003770, 210, 134, 0.02%, Tomato, puree-Cooked; Fresh or N/S; Cook Meth N/S 8002340, 212, 39, 0.02%, Okra-Cooked; Fresh or N/S; Boiled15003250, 230, 76, 0.02%, Rice, flour-Cooked; Dried; Cook Meth N/S95003600, 110, 6, 0.02%, Strawberry, juice-Uncooked; Fresh or N/S; Cook MethN/S21000440, 212, 174, 0.02%, Beef, meat-Cooked; Fresh or N/S; Boiled 8002700, 215, 24, 0.02%, Pepper, bell-Cooked; Fresh or N/S; Boiled/baked 8002720, 215, 122, 0.02%, Pepper, nonbell-Cooked; Fresh or N/S; Boiled/baked15003250, 210, 62, 0.02%, Rice, flour-Cooked; Fresh or N/S; Cook Meth N/S25002930, 212, 87, 0.02%, Pork, fat-Cooked; Fresh or N/S; Boiled 8002700, 212, 12, 0.02%, Pepper, bell-Cooked; Fresh or N/S; Boiled12000130, 211, 4, 0.02%, Apricot, dried-Cooked; Fresh or N/S; Baked12000120, 240, 7, 0.02%, Apricot-Cooked; Canned; Cook Meth N/S15003250, 232, 38, 0.01%, Rice, flour-Cooked; Dried; Boiled12000130, 130, 7, 0.01%, Apricot, dried-Uncooked; Dried; Cook Meth N/S 8002700, 221, 6, 0.01%, Pepper, bell-Cooked; Frozen; Baked21000470, 212, 129, 0.01%, Beef, fat-Cooked; Fresh or N/S; Boiled 8002730, 240, 90, 0.01%, Pepper, nonbell, dried-Cooked; Canned; Cook MethN/S12000910, 240, 44, 0.01%, Cherry, juice-Cooked; Canned; Cook Meth N/S 6010430, 222, 3, 0.01%, Bean, snap, succulent-Cooked; Frozen; Boiled95003590, 120, 4, 0.01%, Strawberry-Uncooked; Frozen; Cook Meth N/S21000470, 211, 92, 0.01%, Beef, fat-Cooked; Fresh or N/S; Baked15001210, 233, 126, 0.01%, Corn, field, meal-Cooked; Dried; Fried95002350, 210, 5, 0.01%, Olive-Cooked; Fresh or N/S; Cook Meth N/S 6010430, 210, 3, 0.01%, Bean, snap, succulent-Cooked; Fresh or N/S; CookMeth N/S12000910, 210, 6, 0.01%, Cherry, juice-Cooked; Fresh or N/S; Cook Meth N/S15004020, 210, 178, 0.01%, Wheat, flour-Cooked; Fresh or N/S; Cook Meth N/S

417

8001480, 214, 3, 0.01%, Eggplant-Cooked; Fresh or N/S; Fried/baked95003590, 211, 5, 0.01%, Strawberry-Cooked; Fresh or N/S; Baked15003250, 212, 19, 0.01%, Rice, flour-Cooked; Fresh or N/S; Boiled 8002730, 213, 85, 0.01%, Pepper, nonbell, dried-Cooked; Fresh or N/S; Fried15001200, 230, 124, 0.01%, Corn, field, flour-Cooked; Dried; Cook Meth N/S13013210, 240, 7, 0.01%, Raspberry, juice-Cooked; Canned; Cook Meth N/S15001240, 130, 64, 0.01%, Corn, field, syrup-Uncooked; Dried; Cook Meth N/S 9014000, 110, 19, 0.01%, Watermelon, juice-Uncooked; Fresh or N/S; Cook MethN/S15001200, 211, 86, 0.01%, Corn, field, flour-Cooked; Fresh or N/S; Baked 9021350, 240, 39, 0.01%, Cucumber-Cooked; Canned; Cook Meth N/S 4012480, 110, 21, 0.01%, Parsley, leaves-Uncooked; Fresh or N/S; Cook MethN/S 8003790, 240, 45, 0.01%, Tomato, juice-Cooked; Canned; Cook Meth N/S13010550, 211, 2, 0.01%, Blackberry-Cooked; Fresh or N/S; Baked15004020, 232, 94, 0.01%, Wheat, flour-Cooked; Dried; Boiled11000110, 212, 12, 0.01%, Apple, sauce-Cooked; Fresh or N/S; Boiled 8002720, 232, 38, 0.01%, Pepper, nonbell-Cooked; Dried; Boiled 8003790, 110, 27, 0.01%, Tomato, juice-Uncooked; Fresh or N/S; Cook Meth N/S95002350, 212, 2, 0.01%, Olive-Cooked; Fresh or N/S; Boiled 8003770, 212, 51, 0.01%, Tomato, puree-Cooked; Fresh or N/S; Boiled 1033000, 212, 29, 0.01%, Potato, tuber, w/o peel-Cooked; Fresh or N/S;Boiled13020570, 230, 2, 0.01%, Blueberry-Cooked; Dried; Cook Meth N/S27002220, 120, 70, 0.01%, Milk, fat-Uncooked; Frozen; Cook Meth N/S95001750, 240, 8, 0.01%, Grape-Cooked; Canned; Cook Meth N/S95001760, 240, 46, 0.01%, Grape, juice-Cooked; Canned; Cook Meth N/S 8003740, 210, 64, 0.01%, Tomatillo-Cooked; Fresh or N/S; Cook Meth N/S27002220, 211, 64, 0.01%, Milk, fat-Cooked; Fresh or N/S; Baked95001320, 240, 47, 0.01%, Cranberry, juice-Cooked; Canned; Cook Meth N/S 4012480, 212, 20, 0.01%, Parsley, leaves-Cooked; Fresh or N/S; Boiled10002410, 240, 47, 0.01%, Orange, juice-Cooked; Canned; Cook Meth N/S11000070, 211, 3, 0.01%, Apple, fruit with peel-Cooked; Fresh or N/S; Baked95002640, 210, 62, 0.01%, Peanut, butter-Cooked; Fresh or N/S; Cook Meth N/S10002000, 232, 21, 0.01%, Lemon, juice-Cooked; Dried; Boiled11000080, 221, 2, 0.01%, Apple, peeled fruit-Cooked; Frozen; Baked13013210, 120, 10, 0.01%, Raspberry, juice-Uncooked; Frozen; Cook Meth N/S95000190, 212, 4, 0.01%, Asparagus-Cooked; Fresh or N/S; Boiled13010560, 110, 2, 0.01%, Blackberry, juice-Uncooked; Fresh or N/S; Cook MethN/S 6030420, 230, 79, 0.01%, Bean, pinto, seed-Cooked; Dried; Cook Meth N/S 5010690, 110, 58, 0.00%, Cabbage-Uncooked; Fresh or N/S; Cook Meth N/S 8003770, 240, 27, 0.00%, Tomato, puree-Cooked; Canned; Cook Meth N/S14002820, 211, 23, 0.00%, Pistachio-Cooked; Fresh or N/S; Baked 8003790, 210, 20, 0.00%, Tomato, juice-Cooked; Fresh or N/S; Cook Meth N/S25002900, 253, 38, 0.00%, Pork, meat-Cooked; Cured etc; Fried 1010500, 250, 20, 0.00%, Beet, garden, roots-Cooked; Cured etc; Cook MethN/S12000900, 240, 4, 0.00%, Cherry-Cooked; Canned; Cook Meth N/S 1031390, 212, 19, 0.00%, Dasheen, corm-Cooked; Fresh or N/S; Boiled15001200, 210, 45, 0.00%, Corn, field, flour-Cooked; Fresh or N/S; Cook MethN/S 6030420, 232, 58, 0.00%, Bean, pinto, seed-Cooked; Dried; Boiled11000090, 230, 24, 0.00%, Apple, dried-Cooked; Dried; Cook Meth N/S 1030820, 210, 19, 0.00%, Cassava-Cooked; Fresh or N/S; Cook Meth N/S11002660, 240, 1, 0.00%, Pear-Cooked; Canned; Cook Meth N/S19011440, 240, 39, 0.00%, Dillweed-Cooked; Canned; Cook Meth N/S95002350, 221, 1, 0.00%, Olive-Cooked; Frozen; Baked15004010, 230, 38, 0.00%, Wheat, grain-Cooked; Dried; Cook Meth N/S15003240, 232, 39, 0.00%, Rice, brown-Cooked; Dried; Boiled 9023080, 211, 26, 0.00%, Pumpkin-Cooked; Fresh or N/S; Baked95001790, 110, 21, 0.00%, Grape, wine and sherry-Uncooked; Fresh or N/S; CookMeth N/S 9023090, 211, 19, 0.00%, Pumpkin, seed-Cooked; Fresh or N/S; Baked15001200, 232, 19, 0.00%, Corn, field, flour-Cooked; Dried; Boiled

418

95002790, 240, 4, 0.00%, Pineapple-Cooked; Canned; Cook Meth N/S15004020, 231, 23, 0.00%, Wheat, flour-Cooked; Dried; Baked95000730, 210, 3, 0.00%, Cactus-Cooked; Fresh or N/S; Cook Meth N/S27002220, 232, 20, 0.00%, Milk, fat-Cooked; Dried; Boiled12002850, 110, 3, 0.00%, Plum-Uncooked; Fresh or N/S; Cook Meth N/S 6030340, 232, 19, 0.00%, Bean, cowpea, seed-Cooked; Dried; Boiled12000900, 210, 1, 0.00%, Cherry-Cooked; Fresh or N/S; Cook Meth N/S 6003480, 230, 19, 0.00%, Soybean, flour-Cooked; Dried; Cook Meth N/S27002220, 210, 25, 0.00%, Milk, fat-Cooked; Fresh or N/S; Cook Meth N/S25002930, 221, 19, 0.00%, Pork, fat-Cooked; Frozen; Baked 8003790, 212, 24, 0.00%, Tomato, juice-Cooked; Fresh or N/S; Boiled15004020, 212, 28, 0.00%, Wheat, flour-Cooked; Fresh or N/S; Boiled 1033660, 212, 14, 0.00%, Sweet potato-Cooked; Fresh or N/S; Boiled95002630, 112, 19, 0.00%, Peanut-Uncooked; Fresh or N/S; Boiled15001210, 210, 19, 0.00%, Corn, field, meal-Cooked; Fresh or N/S; Cook MethN/S20003640, 211, 20, 0.00%, Sunflower, seed-Cooked; Fresh or N/S; Baked11002680, 120, 6, 0.00%, Pear, juice-Uncooked; Frozen; Cook Meth N/S12000900, 120, 3, 0.00%, Cherry-Uncooked; Frozen; Cook Meth N/S10001800, 110, 9, 0.00%, Grapefruit-Uncooked; Fresh or N/S; Cook Meth N/S25002900, 212, 22, 0.00%, Pork, meat-Cooked; Fresh or N/S; Boiled15001200, 213, 21, 0.00%, Corn, field, flour-Cooked; Fresh or N/S; Fried 6032030, 232, 19, 0.00%, Lentil, seed-Cooked; Dried; Boiled15001260, 230, 25, 0.00%, Corn, pop-Cooked; Dried; Cook Meth N/S 8003750, 110, 21, 0.00%, Tomato-Uncooked; Fresh or N/S; Cook Meth N/S95001750, 120, 1, 0.00%, Grape-Uncooked; Frozen; Cook Meth N/S21000490, 210, 19, 0.00%, Beef, liver-Cooked; Fresh or N/S; Cook Meth N/S 6003490, 210, 15, 0.00%, Soybean, soy milk-Cooked; Fresh or N/S; Cook MethN/S 1033660, 211, 7, 0.00%, Sweet potato-Cooked; Fresh or N/S; Baked27002220, 215, 19, 0.00%, Milk, fat-Cooked; Fresh or N/S; Boiled/baked27002220, 230, 17, 0.00%, Milk, fat-Cooked; Dried; Cook Meth N/S21000460, 210, 19, 0.00%, Beef, meat byproducts-Cooked; Fresh or N/S; CookMeth N/S 8003750, 211, 15, 0.00%, Tomato-Cooked; Fresh or N/S; Baked15004020, 215, 19, 0.00%, Wheat, flour-Cooked; Fresh or N/S; Boiled/baked15001210, 230, 22, 0.00%, Corn, field, meal-Cooked; Dried; Cook Meth N/S15001240, 120, 18, 0.00%, Corn, field, syrup-Uncooked; Frozen; Cook Meth N/S14000810, 211, 8, 0.00%, Cashew-Cooked; Fresh or N/S; Baked 8003750, 240, 14, 0.00%, Tomato-Cooked; Canned; Cook Meth N/S25002920, 210, 20, 0.00%, Pork, meat byproducts-Cooked; Fresh or N/S; CookMeth N/S15001210, 211, 22, 0.00%, Corn, field, meal-Cooked; Fresh or N/S; Baked 1032990, 212, 5, 0.00%, Potato, tuber, w/peel-Cooked; Fresh or N/S; Boiled11002660, 210, 1, 0.00%, Pear-Cooked; Fresh or N/S; Cook Meth N/S95002790, 110, 4, 0.00%, Pineapple-Uncooked; Fresh or N/S; Cook Meth N/S15003240, 210, 3, 0.00%, Rice, brown-Cooked; Fresh or N/S; Cook Meth N/S11002680, 110, 4, 0.00%, Pear, juice-Uncooked; Fresh or N/S; Cook Meth N/S11000100, 240, 9, 0.00%, Apple, juice-Cooked; Canned; Cook Meth N/S15004020, 214, 20, 0.00%, Wheat, flour-Cooked; Fresh or N/S; Fried/baked12000140, 240, 2, 0.00%, Apricot, juice-Cooked; Canned; Cook Meth N/S25002930, 240, 2, 0.00%, Pork, fat-Cooked; Canned; Cook Meth N/S 9021020, 210, 2, 0.00%, Chinese waxgourd-Cooked; Fresh or N/S; Cook MethN/S 8002730, 221, 3, 0.00%, Pepper, nonbell, dried-Cooked; Frozen; Baked12002600, 120, 4, 0.00%, Peach-Uncooked; Frozen; Cook Meth N/S 4012480, 210, 6, 0.00%, Parsley, leaves-Cooked; Fresh or N/S; Cook Meth N/S 9011870, 110, 2, 0.00%, Honeydew melon-Uncooked; Fresh or N/S; Cook MethN/S11000090, 210, 3, 0.00%, Apple, dried-Cooked; Fresh or N/S; Cook Meth N/S 8001480, 210, 1, 0.00%, Eggplant-Cooked; Fresh or N/S; Cook Meth N/S 1032990, 211, 5, 0.00%, Potato, tuber, w/peel-Cooked; Fresh or N/S; Baked 9021350, 150, 6, 0.00%, Cucumber-Uncooked; Cured etc; Cook Meth N/S12000140, 120, 1, 0.00%, Apricot, juice-Uncooked; Frozen; Cook Meth N/S14003910, 211, 2, 0.00%, Walnut-Cooked; Fresh or N/S; Baked

419

14002690, 211, 3, 0.00%, Pecan-Cooked; Fresh or N/S; Baked20003640, 110, 2, 0.00%, Sunflower, seed-Uncooked; Fresh or N/S; Cook MethN/S 8003750, 215, 7, 0.00%, Tomato-Cooked; Fresh or N/S; Boiled/baked95000230, 110, 7, 0.00%, Banana-Uncooked; Fresh or N/S; Cook Meth N/S 8003760, 212, 5, 0.00%, Tomato, paste-Cooked; Fresh or N/S; Boiled95001320, 110, 2, 0.00%, Cranberry, juice-Uncooked; Fresh or N/S; Cook MethN/S21000470, 250, 5, 0.00%, Beef, fat-Cooked; Cured etc; Cook Meth N/S95002630, 211, 3, 0.00%, Peanut-Cooked; Fresh or N/S; Baked 8003750, 210, 6, 0.00%, Tomato-Cooked; Fresh or N/S; Cook Meth N/S15004010, 211, 4, 0.00%, Wheat, grain-Cooked; Fresh or N/S; Baked13021370, 211, 1, 0.00%, Currant, dried-Cooked; Fresh or N/S; Baked15001270, 212, 2, 0.00%, Corn, sweet-Cooked; Fresh or N/S; Boiled25002930, 222, 1, 0.00%, Pork, fat-Cooked; Frozen; Boiled11000100, 120, 3, 0.00%, Apple, juice-Uncooked; Frozen; Cook Meth N/S 8002720, 242, 1, 0.00%, Pepper, nonbell-Cooked; Canned; Boiled 1034060, 210, 1, 0.00%, Yam, true-Cooked; Fresh or N/S; Cook Meth N/S25002930, 214, 2, 0.00%, Pork, fat-Cooked; Fresh or N/S; Fried/baked15001240, 230, 3, 0.00%, Corn, field, syrup-Cooked; Dried; Cook Meth N/S 9023570, 215, 4, 0.00%, Squash, winter-Cooked; Fresh or N/S; Boiled/baked21000460, 212, 2, 0.00%, Beef, meat byproducts-Cooked; Fresh or N/S; Boiled21000450, 230, 2, 0.00%, Beef, meat, dried-Cooked; Dried; Cook Meth N/S12002860, 211, 2, 0.00%, Plum, prune, fresh-Cooked; Fresh or N/S; Baked20003650, 900, 2, 0.00%, Sunflower, oil-Refined; FF N/A; Cook Meth N/S 8003750, 212, 3, 0.00%, Tomato-Cooked; Fresh or N/S; Boiled 4020860, 240, 2, 0.00%, Celery, juice-Cooked; Canned; Cook Meth N/S 5010830, 222, 1, 0.00%, Cauliflower-Cooked; Frozen; Boiled 1033660, 210, 2, 0.00%, Sweet potato-Cooked; Fresh or N/S; Cook Meth N/S95002810, 211, 1, 0.00%, Pineapple, juice-Cooked; Fresh or N/S; Baked15001200, 231, 2, 0.00%, Corn, field, flour-Cooked; Dried; Baked11002680, 240, 1, 0.00%, Pear, juice-Cooked; Canned; Cook Meth N/S15001210, 232, 2, 0.00%, Corn, field, meal-Cooked; Dried; Boiled21000440, 250, 2, 0.00%, Beef, meat-Cooked; Cured etc; Cook Meth N/S 8003760, 210, 2, 0.00%, Tomato, paste-Cooked; Fresh or N/S; Cook Meth N/S10001060, 211, 1, 0.00%, Citrus citron-Cooked; Fresh or N/S; Baked 9023560, 212, 1, 0.00%, Squash, summer-Cooked; Fresh or N/S; Boiled 9023080, 212, 2, 0.00%, Pumpkin-Cooked; Fresh or N/S; Boiled 1033000, 211, 1, 0.00%, Potato, tuber, w/o peel-Cooked; Fresh or N/S; Baked 1013140, 110, 1, 0.00%, Radish, roots-Uncooked; Fresh or N/S; Cook Meth N/S20003640, 210, 1, 0.00%, Sunflower, seed-Cooked; Fresh or N/S; Cook Meth N/S95002790, 210, 1, 0.00%, Pineapple-Cooked; Fresh or N/S; Cook Meth N/S95003600, 120, 1, 0.00%, Strawberry, juice-Uncooked; Frozen; Cook Meth N/S95001760, 120, 1, 0.00%, Grape, juice-Uncooked; Frozen; Cook Meth N/S26003390, 210, 1, 0.00%, Sheep, meat-Cooked; Fresh or N/S; Cook Meth N/S 1033000, 210, 1, 0.00%, Potato, tuber, w/o peel-Cooked; Fresh or N/S; CookMeth N/S15001260, 210, 1, 0.00%, Corn, pop-Cooked; Fresh or N/S; Cook Meth N/S 8003770, 242, 1, 0.00%, Tomato, puree-Cooked; Canned; Boiled15001270, 222, 1, 0.00%, Corn, sweet-Cooked; Frozen; Boiled 1010500, 212, 1, 0.00%, Beet, garden, roots-Cooked; Fresh or N/S; Boiled95002630, 210, 1, 0.00%, Peanut-Cooked; Fresh or N/S; Cook Meth N/S 8002700, 232, 1, 0.00%, Pepper, bell-Cooked; Dried; Boiled 5010830, 110, 1, 0.00%, Cauliflower-Uncooked; Fresh or N/S; Cook Meth N/S27002220, 212, 1, 0.00%, Milk, fat-Cooked; Fresh or N/S; Boiled10002010, 230, 1, 0.00%, Lemon, peel-Cooked; Dried; Cook Meth N/S15004020, 213, 1, 0.00%, Wheat, flour-Cooked; Fresh or N/S; Fried 4012040, 110, 1, 0.00%, Lettuce, head-Uncooked; Fresh or N/S; Cook Meth N/S 8003770, 211, 1, 0.00%, Tomato, puree-Cooked; Fresh or N/S; Baked

420

Adults 50+ yrsLow percentile for CEC records: 95 Exposure (mg/day) = 0.000329High percentile for CEC records: 100 Exposure (mg/day) = 0.045247Number of actual records in this interval: 9137

Critical foods/foodforms for this population (as derived from these records): N=number of appearances in all records (including duplicates) %=percent of total exposure for all records (including duplicates)

Food, FF, N , Percent, Food Name --------, ---, -----, -------, -------------12002880, 110, 1278, 21.84%, Plum, prune, juice-Uncooked; Fresh or N/S; CookMeth N/S 5022290, 212, 628, 12.24%, Mustard greens-Cooked; Fresh or N/S; Boiled 4023220, 240, 114, 5.62%, Rhubarb-Cooked; Canned; Cook Meth N/S 4023670, 212, 152, 5.35%, Swiss chard-Cooked; Fresh or N/S; Boiled 8002720, 110, 841, 5.01%, Pepper, nonbell-Uncooked; Fresh or N/S; Cook MethN/S 8002340, 210, 627, 4.54%, Okra-Cooked; Fresh or N/S; Cook Meth N/S 4023220, 211, 266, 4.06%, Rhubarb-Cooked; Fresh or N/S; Baked10001810, 110, 1097, 3.30%, Grapefruit, juice-Uncooked; Fresh or N/S; Cook MethN/S 4020860, 110, 133, 2.89%, Celery, juice-Uncooked; Fresh or N/S; Cook Meth N/S 8002720, 210, 479, 2.57%, Pepper, nonbell-Cooked; Fresh or N/S; Cook Meth N/S 5020700, 210, 266, 1.86%, Cabbage, Chinese, bok choy-Cooked; Fresh or N/S;Cook Meth N/S 5022290, 242, 115, 1.81%, Mustard greens-Cooked; Canned; Boiled10002000, 110, 847, 1.74%, Lemon, juice-Uncooked; Fresh or N/S; Cook Meth N/S12002610, 130, 171, 1.27%, Peach, dried-Uncooked; Dried; Cook Meth N/S 5020700, 150, 133, 1.26%, Cabbage, Chinese, bok choy-Uncooked; Cured etc;Cook Meth N/S12002620, 110, 114, 1.25%, Peach, juice-Uncooked; Fresh or N/S; Cook Meth N/S 8002340, 220, 209, 1.24%, Okra-Cooked; Frozen; Cook Meth N/S 5022290, 222, 57, 1.22%, Mustard greens-Cooked; Frozen; Boiled 4023220, 120, 38, 1.15%, Rhubarb-Uncooked; Frozen; Cook Meth N/S 8002340, 213, 270, 1.15%, Okra-Cooked; Fresh or N/S; Fried 8002720, 213, 212, 1.10%, Pepper, nonbell-Cooked; Fresh or N/S; Fried11000070, 110, 229, 1.03%, Apple, fruit with peel-Uncooked; Fresh or N/S; CookMeth N/S 8002720, 240, 354, 0.84%, Pepper, nonbell-Cooked; Canned; Cook Meth N/S 8002720, 212, 236, 0.79%, Pepper, nonbell-Cooked; Fresh or N/S; Boiled13020570, 211, 86, 0.77%, Blueberry-Cooked; Fresh or N/S; Baked13013200, 240, 164, 0.54%, Raspberry-Cooked; Canned; Cook Meth N/S95002810, 110, 289, 0.53%, Pineapple, juice-Uncooked; Fresh or N/S; Cook MethN/S10002070, 110, 253, 0.51%, Lime, juice-Uncooked; Fresh or N/S; Cook Meth N/S95001750, 110, 101, 0.51%, Grape-Uncooked; Fresh or N/S; Cook Meth N/S11000090, 211, 318, 0.47%, Apple, dried-Cooked; Fresh or N/S; Baked13020570, 110, 54, 0.45%, Blueberry-Uncooked; Fresh or N/S; Cook Meth N/S 8002700, 210, 122, 0.40%, Pepper, bell-Cooked; Fresh or N/S; Cook Meth N/S 9010800, 110, 57, 0.40%, Casaba-Uncooked; Fresh or N/S; Cook Meth N/S11000090, 130, 190, 0.39%, Apple, dried-Uncooked; Dried; Cook Meth N/S95002350, 240, 53, 0.38%, Olive-Cooked; Canned; Cook Meth N/S13013200, 120, 17, 0.35%, Raspberry-Uncooked; Frozen; Cook Meth N/S12002600, 110, 81, 0.35%, Peach-Uncooked; Fresh or N/S; Cook Meth N/S 8002720, 220, 19, 0.32%, Pepper, nonbell-Cooked; Frozen; Cook Meth N/S13010580, 120, 62, 0.31%, Boysenberry-Uncooked; Frozen; Cook Meth N/S 5020700, 110, 38, 0.30%, Cabbage, Chinese, bok choy-Uncooked; Fresh or N/S;Cook Meth N/S 8002700, 110, 125, 0.28%, Pepper, bell-Uncooked; Fresh or N/S; Cook Meth N/S10003690, 110, 176, 0.27%, Tangerine-Uncooked; Fresh or N/S; Cook Meth N/S12002600, 240, 95, 0.25%, Peach-Cooked; Canned; Cook Meth N/S 8002340, 150, 78, 0.25%, Okra-Uncooked; Cured etc; Cook Meth N/S 8002720, 221, 76, 0.22%, Pepper, nonbell-Cooked; Frozen; Baked

421

95002800, 130, 190, 0.21%, Pineapple, dried-Uncooked; Dried; Cook Meth N/S 8002720, 150, 65, 0.19%, Pepper, nonbell-Uncooked; Cured etc; Cook Meth N/S13013200, 110, 39, 0.19%, Raspberry-Uncooked; Fresh or N/S; Cook Meth N/S11002660, 110, 47, 0.18%, Pear-Uncooked; Fresh or N/S; Cook Meth N/S10001810, 120, 60, 0.18%, Grapefruit, juice-Uncooked; Frozen; Cook Meth N/S13021370, 130, 19, 0.18%, Currant, dried-Uncooked; Dried; Cook Meth N/S13010550, 211, 13, 0.15%, Blackberry-Cooked; Fresh or N/S; Baked11002670, 130, 152, 0.14%, Pear, dried-Uncooked; Dried; Cook Meth N/S12000900, 211, 37, 0.13%, Cherry-Cooked; Fresh or N/S; Baked13010550, 240, 82, 0.13%, Blackberry-Cooked; Canned; Cook Meth N/S25002930, 210, 782, 0.13%, Pork, fat-Cooked; Fresh or N/S; Cook Meth N/S25002930, 213, 486, 0.12%, Pork, fat-Cooked; Fresh or N/S; Fried12000900, 110, 35, 0.11%, Cherry-Uncooked; Fresh or N/S; Cook Meth N/S10003700, 110, 136, 0.10%, Tangerine, juice-Uncooked; Fresh or N/S; Cook MethN/S12000910, 110, 117, 0.10%, Cherry, juice-Uncooked; Fresh or N/S; Cook Meth N/S10001810, 240, 154, 0.10%, Grapefruit, juice-Cooked; Canned; Cook Meth N/S 8002340, 212, 62, 0.10%, Okra-Cooked; Fresh or N/S; Boiled10002000, 130, 21, 0.10%, Lemon, juice-Uncooked; Dried; Cook Meth N/S13010580, 110, 98, 0.08%, Boysenberry-Uncooked; Fresh or N/S; Cook Meth N/S10002000, 120, 41, 0.08%, Lemon, juice-Uncooked; Frozen; Cook Meth N/S12002300, 110, 17, 0.08%, Nectarine-Uncooked; Fresh or N/S; Cook Meth N/S10002000, 211, 380, 0.07%, Lemon, juice-Cooked; Fresh or N/S; Baked10002000, 240, 259, 0.06%, Lemon, juice-Cooked; Canned; Cook Meth N/S12002600, 211, 18, 0.06%, Peach-Cooked; Fresh or N/S; Baked11002660, 240, 23, 0.06%, Pear-Cooked; Canned; Cook Meth N/S95002350, 211, 17, 0.05%, Olive-Cooked; Fresh or N/S; Baked10001070, 110, 20, 0.05%, Citrus hybrids-Uncooked; Fresh or N/S; Cook MethN/S12002620, 240, 22, 0.05%, Peach, juice-Cooked; Canned; Cook Meth N/S12000120, 240, 18, 0.05%, Apricot-Cooked; Canned; Cook Meth N/S95003590, 110, 23, 0.05%, Strawberry-Uncooked; Fresh or N/S; Cook Meth N/S 8002730, 212, 133, 0.04%, Pepper, nonbell, dried-Cooked; Fresh or N/S; Boiled11000070, 211, 7, 0.04%, Apple, fruit with peel-Cooked; Fresh or N/S; Baked11000080, 211, 17, 0.04%, Apple, peeled fruit-Cooked; Fresh or N/S; Baked25002930, 250, 414, 0.04%, Pork, fat-Cooked; Cured etc; Cook Meth N/S13020570, 213, 4, 0.04%, Blueberry-Cooked; Fresh or N/S; Fried12002600, 120, 5, 0.04%, Peach-Uncooked; Frozen; Cook Meth N/S95002810, 240, 199, 0.03%, Pineapple, juice-Cooked; Canned; Cook Meth N/S13020570, 120, 12, 0.03%, Blueberry-Uncooked; Frozen; Cook Meth N/S 6010430, 242, 12, 0.03%, Bean, snap, succulent-Cooked; Canned; Boiled25002930, 253, 341, 0.03%, Pork, fat-Cooked; Cured etc; Fried 9010750, 110, 36, 0.03%, Cantaloupe-Uncooked; Fresh or N/S; Cook Meth N/S10002410, 110, 343, 0.03%, Orange, juice-Uncooked; Fresh or N/S; Cook Meth N/S10003700, 240, 127, 0.03%, Tangerine, juice-Cooked; Canned; Cook Meth N/S 6010430, 212, 12, 0.03%, Bean, snap, succulent-Cooked; Fresh or N/S; Boiled13010580, 240, 125, 0.03%, Boysenberry-Cooked; Canned; Cook Meth N/S95003590, 240, 19, 0.03%, Strawberry-Cooked; Canned; Cook Meth N/S25002930, 211, 147, 0.03%, Pork, fat-Cooked; Fresh or N/S; Baked95001760, 110, 110, 0.02%, Grape, juice-Uncooked; Fresh or N/S; Cook Meth N/S13013210, 110, 13, 0.02%, Raspberry, juice-Uncooked; Fresh or N/S; Cook MethN/S15001240, 110, 275, 0.02%, Corn, field, syrup-Uncooked; Fresh or N/S; CookMeth N/S15001240, 240, 472, 0.02%, Corn, field, syrup-Cooked; Canned; Cook Meth N/S10002070, 240, 127, 0.02%, Lime, juice-Cooked; Canned; Cook Meth N/S 4012480, 110, 82, 0.02%, Parsley, leaves-Uncooked; Fresh or N/S; Cook MethN/S95002360, 900, 157, 0.02%, Olive, oil-Refined; FF N/A; Cook Meth N/S95002810, 120, 22, 0.02%, Pineapple, juice-Uncooked; Frozen; Cook Meth N/S12000130, 130, 32, 0.02%, Apricot, dried-Uncooked; Dried; Cook Meth N/S12000130, 211, 8, 0.02%, Apricot, dried-Cooked; Fresh or N/S; Baked 8002700, 213, 17, 0.02%, Pepper, bell-Cooked; Fresh or N/S; Fried25002900, 210, 231, 0.02%, Pork, meat-Cooked; Fresh or N/S; Cook Meth N/S95002350, 210, 3, 0.02%, Olive-Cooked; Fresh or N/S; Cook Meth N/S

422

8002700, 150, 12, 0.02%, Pepper, bell-Uncooked; Cured etc; Cook Meth N/S13013200, 211, 16, 0.02%, Raspberry-Cooked; Fresh or N/S; Baked13010550, 110, 14, 0.02%, Blackberry-Uncooked; Fresh or N/S; Cook Meth N/S11000110, 212, 42, 0.02%, Apple, sauce-Cooked; Fresh or N/S; Boiled25002900, 250, 280, 0.02%, Pork, meat-Cooked; Cured etc; Cook Meth N/S15004020, 211, 374, 0.02%, Wheat, flour-Cooked; Fresh or N/S; Baked15003250, 230, 108, 0.02%, Rice, flour-Cooked; Dried; Cook Meth N/S11000100, 110, 65, 0.02%, Apple, juice-Uncooked; Fresh or N/S; Cook Meth N/S12000140, 110, 2, 0.01%, Apricot, juice-Uncooked; Fresh or N/S; Cook MethN/S 4011500, 110, 109, 0.01%, Endive-Uncooked; Fresh or N/S; Cook Meth N/S25002930, 232, 86, 0.01%, Pork, fat-Cooked; Dried; Boiled25002930, 212, 176, 0.01%, Pork, fat-Cooked; Fresh or N/S; Boiled12000120, 232, 2, 0.01%, Apricot-Cooked; Dried; Boiled13020570, 230, 3, 0.01%, Blueberry-Cooked; Dried; Cook Meth N/S 8002730, 240, 112, 0.01%, Pepper, nonbell, dried-Cooked; Canned; Cook MethN/S 8002700, 221, 9, 0.01%, Pepper, bell-Cooked; Frozen; Baked10002410, 120, 112, 0.01%, Orange, juice-Uncooked; Frozen; Cook Meth N/S 6010430, 222, 4, 0.01%, Bean, snap, succulent-Cooked; Frozen; Boiled13010560, 110, 1, 0.01%, Blackberry, juice-Uncooked; Fresh or N/S; Cook MethN/S95001750, 240, 18, 0.01%, Grape-Cooked; Canned; Cook Meth N/S12000900, 120, 7, 0.01%, Cherry-Uncooked; Frozen; Cook Meth N/S10001990, 110, 83, 0.01%, Lemon-Uncooked; Fresh or N/S; Cook Meth N/S21000440, 210, 220, 0.01%, Beef, meat-Cooked; Fresh or N/S; Cook Meth N/S21000440, 211, 209, 0.01%, Beef, meat-Cooked; Fresh or N/S; Baked95003600, 240, 11, 0.01%, Strawberry, juice-Cooked; Canned; Cook Meth N/S21000470, 210, 155, 0.01%, Beef, fat-Cooked; Fresh or N/S; Cook Meth N/S 9021350, 110, 44, 0.01%, Cucumber-Uncooked; Fresh or N/S; Cook Meth N/S10002400, 110, 11, 0.01%, Orange-Uncooked; Fresh or N/S; Cook Meth N/S 8003790, 110, 44, 0.01%, Tomato, juice-Uncooked; Fresh or N/S; Cook Meth N/S10002000, 210, 45, 0.01%, Lemon, juice-Cooked; Fresh or N/S; Cook Meth N/S13020570, 214, 1, 0.01%, Blueberry-Cooked; Fresh or N/S; Fried/baked15001200, 214, 58, 0.01%, Corn, field, flour-Cooked; Fresh or N/S;Fried/baked25002900, 211, 98, 0.01%, Pork, meat-Cooked; Fresh or N/S; Baked25002930, 230, 65, 0.01%, Pork, fat-Cooked; Dried; Cook Meth N/S27002220, 110, 173, 0.01%, Milk, fat-Uncooked; Fresh or N/S; Cook Meth N/S12000910, 240, 44, 0.01%, Cherry, juice-Cooked; Canned; Cook Meth N/S 8002730, 210, 70, 0.01%, Pepper, nonbell, dried-Cooked; Fresh or N/S; CookMeth N/S11000070, 213, 2, 0.01%, Apple, fruit with peel-Cooked; Fresh or N/S; Fried 8002730, 213, 59, 0.01%, Pepper, nonbell, dried-Cooked; Fresh or N/S; Fried12000120, 211, 1, 0.01%, Apricot-Cooked; Fresh or N/S; Baked25002900, 213, 77, 0.01%, Pork, meat-Cooked; Fresh or N/S; Fried21000440, 213, 123, 0.01%, Beef, meat-Cooked; Fresh or N/S; Fried10002000, 232, 25, 0.01%, Lemon, juice-Cooked; Dried; Boiled95000730, 210, 19, 0.01%, Cactus-Cooked; Fresh or N/S; Cook Meth N/S95000190, 212, 12, 0.01%, Asparagus-Cooked; Fresh or N/S; Boiled25002930, 240, 7, 0.01%, Pork, fat-Cooked; Canned; Cook Meth N/S 8003790, 212, 67, 0.01%, Tomato, juice-Cooked; Fresh or N/S; Boiled 9011870, 110, 7, 0.01%, Honeydew melon-Uncooked; Fresh or N/S; Cook MethN/S 8003770, 210, 95, 0.01%, Tomato, puree-Cooked; Fresh or N/S; Cook Meth N/S 8002700, 211, 6, 0.01%, Pepper, bell-Cooked; Fresh or N/S; Baked95003590, 211, 5, 0.01%, Strawberry-Cooked; Fresh or N/S; Baked 5010690, 110, 87, 0.01%, Cabbage-Uncooked; Fresh or N/S; Cook Meth N/S13020570, 210, 2, 0.01%, Blueberry-Cooked; Fresh or N/S; Cook Meth N/S 8003790, 240, 28, 0.01%, Tomato, juice-Cooked; Canned; Cook Meth N/S 9014000, 110, 19, 0.01%, Watermelon, juice-Uncooked; Fresh or N/S; Cook MethN/S11000090, 230, 11, 0.01%, Apple, dried-Cooked; Dried; Cook Meth N/S21000440, 212, 99, 0.00%, Beef, meat-Cooked; Fresh or N/S; Boiled12000120, 110, 2, 0.00%, Apricot-Uncooked; Fresh or N/S; Cook Meth N/S

423

8002720, 232, 21, 0.00%, Pepper, nonbell-Cooked; Dried; Boiled 1031390, 213, 20, 0.00%, Dasheen, corm-Cooked; Fresh or N/S; Fried12000900, 240, 11, 0.00%, Cherry-Cooked; Canned; Cook Meth N/S21000460, 210, 39, 0.00%, Beef, meat byproducts-Cooked; Fresh or N/S; CookMeth N/S 4011380, 212, 2, 0.00%, Dandelion, leaves-Cooked; Fresh or N/S; Boiled 1010790, 110, 20, 0.00%, Carrot, juice-Uncooked; Fresh or N/S; Cook Meth N/S 8002720, 215, 39, 0.00%, Pepper, nonbell-Cooked; Fresh or N/S; Boiled/baked12002850, 110, 7, 0.00%, Plum-Uncooked; Fresh or N/S; Cook Meth N/S21000470, 212, 61, 0.00%, Beef, fat-Cooked; Fresh or N/S; Boiled 1033000, 212, 25, 0.00%, Potato, tuber, w/o peel-Cooked; Fresh or N/S;Boiled11002680, 240, 6, 0.00%, Pear, juice-Cooked; Canned; Cook Meth N/S15001260, 230, 42, 0.00%, Corn, pop-Cooked; Dried; Cook Meth N/S 8002700, 212, 4, 0.00%, Pepper, bell-Cooked; Fresh or N/S; Boiled27002220, 120, 67, 0.00%, Milk, fat-Uncooked; Frozen; Cook Meth N/S 4013550, 242, 2, 0.00%, Spinach-Cooked; Canned; Boiled12000120, 213, 2, 0.00%, Apricot-Cooked; Fresh or N/S; Fried 2001010, 110, 58, 0.00%, Chicory, tops-Uncooked; Fresh or N/S; Cook Meth N/S12000140, 240, 1, 0.00%, Apricot, juice-Cooked; Canned; Cook Meth N/S95002630, 211, 29, 0.00%, Peanut-Cooked; Fresh or N/S; Baked 6010430, 240, 1, 0.00%, Bean, snap, succulent-Cooked; Canned; Cook Meth N/S 6010430, 210, 1, 0.00%, Bean, snap, succulent-Cooked; Fresh or N/S; CookMeth N/S21000470, 211, 57, 0.00%, Beef, fat-Cooked; Fresh or N/S; Baked95001320, 240, 30, 0.00%, Cranberry, juice-Cooked; Canned; Cook Meth N/S21000470, 213, 60, 0.00%, Beef, fat-Cooked; Fresh or N/S; Fried 8002700, 215, 8, 0.00%, Pepper, bell-Cooked; Fresh or N/S; Boiled/baked95001760, 240, 29, 0.00%, Grape, juice-Cooked; Canned; Cook Meth N/S15004020, 231, 56, 0.00%, Wheat, flour-Cooked; Dried; Baked15001200, 213, 37, 0.00%, Corn, field, flour-Cooked; Fresh or N/S; Fried95003600, 120, 1, 0.00%, Strawberry, juice-Uncooked; Frozen; Cook Meth N/S11000080, 110, 1, 0.00%, Apple, peeled fruit-Uncooked; Fresh or N/S; CookMeth N/S95001790, 110, 15, 0.00%, Grape, wine and sherry-Uncooked; Fresh or N/S; CookMeth N/S15004020, 232, 57, 0.00%, Wheat, flour-Cooked; Dried; Boiled10002000, 212, 7, 0.00%, Lemon, juice-Cooked; Fresh or N/S; Boiled 8002730, 232, 21, 0.00%, Pepper, nonbell, dried-Cooked; Dried; Boiled15003240, 232, 22, 0.00%, Rice, brown-Cooked; Dried; Boiled 8003750, 110, 30, 0.00%, Tomato-Uncooked; Fresh or N/S; Cook Meth N/S11000100, 240, 6, 0.00%, Apple, juice-Cooked; Canned; Cook Meth N/S10003700, 120, 22, 0.00%, Tangerine, juice-Uncooked; Frozen; Cook Meth N/S10002420, 210, 19, 0.00%, Orange, peel-Cooked; Fresh or N/S; Cook Meth N/S12002870, 130, 9, 0.00%, Plum, prune, dried-Uncooked; Dried; Cook Meth N/S11000080, 213, 3, 0.00%, Apple, peeled fruit-Cooked; Fresh or N/S; Fried15001240, 130, 20, 0.00%, Corn, field, syrup-Uncooked; Dried; Cook Meth N/S 6010430, 221, 2, 0.00%, Bean, snap, succulent-Cooked; Frozen; Baked 1032990, 212, 12, 0.00%, Potato, tuber, w/peel-Cooked; Fresh or N/S; Boiled95000190, 242, 10, 0.00%, Asparagus-Cooked; Canned; Boiled15001240, 120, 21, 0.00%, Corn, field, syrup-Uncooked; Frozen; Cook Meth N/S95002350, 212, 1, 0.00%, Olive-Cooked; Fresh or N/S; Boiled 1033660, 212, 24, 0.00%, Sweet potato-Cooked; Fresh or N/S; Boiled10002070, 120, 21, 0.00%, Lime, juice-Uncooked; Frozen; Cook Meth N/S 9021350, 240, 16, 0.00%, Cucumber-Cooked; Canned; Cook Meth N/S25002930, 242, 21, 0.00%, Pork, fat-Cooked; Canned; Boiled15001210, 211, 23, 0.00%, Corn, field, meal-Cooked; Fresh or N/S; Baked15001210, 232, 19, 0.00%, Corn, field, meal-Cooked; Dried; Boiled 4020860, 240, 21, 0.00%, Celery, juice-Cooked; Canned; Cook Meth N/S12000910, 120, 21, 0.00%, Cherry, juice-Uncooked; Frozen; Cook Meth N/S95002640, 210, 23, 0.00%, Peanut, butter-Cooked; Fresh or N/S; Cook Meth N/S10001060, 211, 5, 0.00%, Citrus citron-Cooked; Fresh or N/S; Baked 1013880, 212, 21, 0.00%, Turnip, roots-Cooked; Fresh or N/S; Boiled27002220, 240, 19, 0.00%, Milk, fat-Cooked; Canned; Cook Meth N/S 8003740, 210, 20, 0.00%, Tomatillo-Cooked; Fresh or N/S; Cook Meth N/S

424

10002410, 240, 8, 0.00%, Orange, juice-Cooked; Canned; Cook Meth N/S 6003490, 210, 17, 0.00%, Soybean, soy milk-Cooked; Fresh or N/S; Cook MethN/S15001200, 210, 20, 0.00%, Corn, field, flour-Cooked; Fresh or N/S; Cook MethN/S25002920, 210, 21, 0.00%, Pork, meat byproducts-Cooked; Fresh or N/S; CookMeth N/S 8003770, 211, 20, 0.00%, Tomato, puree-Cooked; Fresh or N/S; Baked12000910, 210, 1, 0.00%, Cherry, juice-Cooked; Fresh or N/S; Cook Meth N/S11002680, 110, 5, 0.00%, Pear, juice-Uncooked; Fresh or N/S; Cook Meth N/S 8002700, 222, 1, 0.00%, Pepper, bell-Cooked; Frozen; Boiled95000230, 110, 22, 0.00%, Banana-Uncooked; Fresh or N/S; Cook Meth N/S25002900, 240, 4, 0.00%, Pork, meat-Cooked; Canned; Cook Meth N/S 8001480, 210, 4, 0.00%, Eggplant-Cooked; Fresh or N/S; Cook Meth N/S27002220, 210, 20, 0.00%, Milk, fat-Cooked; Fresh or N/S; Cook Meth N/S95002790, 240, 6, 0.00%, Pineapple-Cooked; Canned; Cook Meth N/S 4012480, 212, 23, 0.00%, Parsley, leaves-Cooked; Fresh or N/S; Boiled13020570, 240, 1, 0.00%, Blueberry-Cooked; Canned; Cook Meth N/S 8003750, 212, 16, 0.00%, Tomato-Cooked; Fresh or N/S; Boiled 1033660, 211, 16, 0.00%, Sweet potato-Cooked; Fresh or N/S; Baked 6030420, 210, 19, 0.00%, Bean, pinto, seed-Cooked; Fresh or N/S; Cook MethN/S14000810, 211, 6, 0.00%, Cashew-Cooked; Fresh or N/S; Baked95001750, 120, 1, 0.00%, Grape-Uncooked; Frozen; Cook Meth N/S 8003770, 221, 17, 0.00%, Tomato, puree-Cooked; Frozen; Baked15001240, 230, 18, 0.00%, Corn, field, syrup-Cooked; Dried; Cook Meth N/S15004040, 230, 20, 0.00%, Wheat, bran-Cooked; Dried; Cook Meth N/S 5010830, 212, 9, 0.00%, Cauliflower-Cooked; Fresh or N/S; Boiled 9013990, 110, 8, 0.00%, Watermelon-Uncooked; Fresh or N/S; Cook Meth N/S15001200, 230, 12, 0.00%, Corn, field, flour-Cooked; Dried; Cook Meth N/S 9021350, 150, 3, 0.00%, Cucumber-Uncooked; Cured etc; Cook Meth N/S15001210, 230, 15, 0.00%, Corn, field, meal-Cooked; Dried; Cook Meth N/S 1033000, 211, 9, 0.00%, Potato, tuber, w/o peel-Cooked; Fresh or N/S; Baked15004020, 210, 9, 0.00%, Wheat, flour-Cooked; Fresh or N/S; Cook Meth N/S 8001480, 214, 2, 0.00%, Eggplant-Cooked; Fresh or N/S; Fried/baked 8001480, 215, 2, 0.00%, Eggplant-Cooked; Fresh or N/S; Boiled/baked15003250, 232, 1, 0.00%, Rice, flour-Cooked; Dried; Boiled 8003770, 212, 7, 0.00%, Tomato, puree-Cooked; Fresh or N/S; Boiled27002220, 211, 11, 0.00%, Milk, fat-Cooked; Fresh or N/S; Baked 2000510, 212, 1, 0.00%, Beet, garden, tops-Cooked; Fresh or N/S; Boiled13021370, 211, 1, 0.00%, Currant, dried-Cooked; Fresh or N/S; Baked 1032990, 211, 5, 0.00%, Potato, tuber, w/peel-Cooked; Fresh or N/S; Baked12002850, 240, 2, 0.00%, Plum-Cooked; Canned; Cook Meth N/S 1031390, 212, 2, 0.00%, Dasheen, corm-Cooked; Fresh or N/S; Boiled 1010500, 212, 6, 0.00%, Beet, garden, roots-Cooked; Fresh or N/S; Boiled 8001480, 213, 1, 0.00%, Eggplant-Cooked; Fresh or N/S; Fried14003910, 211, 2, 0.00%, Walnut-Cooked; Fresh or N/S; Baked95002810, 211, 5, 0.00%, Pineapple, juice-Cooked; Fresh or N/S; Baked21000440, 214, 4, 0.00%, Beef, meat-Cooked; Fresh or N/S; Fried/baked21000470, 250, 5, 0.00%, Beef, fat-Cooked; Cured etc; Cook Meth N/S 1033660, 242, 6, 0.00%, Sweet potato-Cooked; Canned; Boiled13013210, 240, 3, 0.00%, Raspberry, juice-Cooked; Canned; Cook Meth N/S21000440, 250, 4, 0.00%, Beef, meat-Cooked; Cured etc; Cook Meth N/S 1010500, 242, 3, 0.00%, Beet, garden, roots-Cooked; Canned; Boiled95002790, 110, 5, 0.00%, Pineapple-Uncooked; Fresh or N/S; Cook Meth N/S 8003750, 211, 2, 0.00%, Tomato-Cooked; Fresh or N/S; Baked95001320, 110, 2, 0.00%, Cranberry, juice-Uncooked; Fresh or N/S; Cook MethN/S11000110, 240, 3, 0.00%, Apple, sauce-Cooked; Canned; Cook Meth N/S 4012480, 210, 3, 0.00%, Parsley, leaves-Cooked; Fresh or N/S; Cook Meth N/S 4011380, 110, 1, 0.00%, Dandelion, leaves-Uncooked; Fresh or N/S; Cook MethN/S 1013140, 110, 5, 0.00%, Radish, roots-Uncooked; Fresh or N/S; Cook Meth N/S 9023560, 212, 4, 0.00%, Squash, summer-Cooked; Fresh or N/S; Boiled 8003750, 210, 2, 0.00%, Tomato-Cooked; Fresh or N/S; Cook Meth N/S

425

6032030, 232, 4, 0.00%, Lentil, seed-Cooked; Dried; Boiled 8002720, 230, 1, 0.00%, Pepper, nonbell-Cooked; Dried; Cook Meth N/S11000110, 211, 1, 0.00%, Apple, sauce-Cooked; Fresh or N/S; Baked15004010, 230, 4, 0.00%, Wheat, grain-Cooked; Dried; Cook Meth N/S12002860, 232, 2, 0.00%, Plum, prune, fresh-Cooked; Dried; Boiled 8002720, 242, 1, 0.00%, Pepper, nonbell-Cooked; Canned; Boiled 8003750, 240, 3, 0.00%, Tomato-Cooked; Canned; Cook Meth N/S10001800, 110, 2, 0.00%, Grapefruit-Uncooked; Fresh or N/S; Cook Meth N/S 1033000, 210, 1, 0.00%, Potato, tuber, w/o peel-Cooked; Fresh or N/S; CookMeth N/S12002620, 211, 1, 0.00%, Peach, juice-Cooked; Fresh or N/S; Baked26003390, 210, 3, 0.00%, Sheep, meat-Cooked; Fresh or N/S; Cook Meth N/S25002900, 253, 3, 0.00%, Pork, meat-Cooked; Cured etc; Fried15003250, 120, 2, 0.00%, Rice, flour-Uncooked; Frozen; Cook Meth N/S10002420, 110, 1, 0.00%, Orange, peel-Uncooked; Fresh or N/S; Cook Meth N/S15004010, 211, 3, 0.00%, Wheat, grain-Cooked; Fresh or N/S; Baked 8003750, 215, 2, 0.00%, Tomato-Cooked; Fresh or N/S; Boiled/baked 9010750, 240, 1, 0.00%, Cantaloupe-Cooked; Canned; Cook Meth N/S25002900, 212, 2, 0.00%, Pork, meat-Cooked; Fresh or N/S; Boiled14002690, 211, 2, 0.00%, Pecan-Cooked; Fresh or N/S; Baked25002900, 251, 3, 0.00%, Pork, meat-Cooked; Cured etc; Baked 8001480, 211, 1, 0.00%, Eggplant-Cooked; Fresh or N/S; Baked 6003490, 230, 2, 0.00%, Soybean, soy milk-Cooked; Dried; Cook Meth N/S 9023080, 211, 2, 0.00%, Pumpkin-Cooked; Fresh or N/S; Baked 8003770, 240, 3, 0.00%, Tomato, puree-Cooked; Canned; Cook Meth N/S 8003760, 212, 2, 0.00%, Tomato, paste-Cooked; Fresh or N/S; Boiled21000440, 221, 2, 0.00%, Beef, meat-Cooked; Frozen; Baked19012490, 221, 2, 0.00%, Parsley, dried leaves-Cooked; Frozen; Baked25002930, 251, 1, 0.00%, Pork, fat-Cooked; Cured etc; Baked95002630, 210, 2, 0.00%, Peanut-Cooked; Fresh or N/S; Cook Meth N/S26003410, 210, 2, 0.00%, Sheep, fat-Cooked; Fresh or N/S; Cook Meth N/S15001210, 233, 2, 0.00%, Corn, field, meal-Cooked; Dried; Fried 5010830, 222, 1, 0.00%, Cauliflower-Cooked; Frozen; Boiled20003640, 230, 1, 0.00%, Sunflower, seed-Cooked; Dried; Cook Meth N/S 4012480, 213, 1, 0.00%, Parsley, leaves-Cooked; Fresh or N/S; Fried15001240, 211, 2, 0.00%, Corn, field, syrup-Cooked; Fresh or N/S; Baked25002900, 232, 1, 0.00%, Pork, meat-Cooked; Dried; Boiled20003640, 110, 1, 0.00%, Sunflower, seed-Uncooked; Fresh or N/S; Cook MethN/S 9023090, 211, 1, 0.00%, Pumpkin, seed-Cooked; Fresh or N/S; Baked15003240, 230, 2, 0.00%, Rice, brown-Cooked; Dried; Cook Meth N/S15001270, 222, 1, 0.00%, Corn, sweet-Cooked; Frozen; Boiled95001760, 120, 1, 0.00%, Grape, juice-Uncooked; Frozen; Cook Meth N/S19012490, 212, 1, 0.00%, Parsley, dried leaves-Cooked; Fresh or N/S; Boiled 8003790, 242, 1, 0.00%, Tomato, juice-Cooked; Canned; Boiled15004020, 213, 1, 0.00%, Wheat, flour-Cooked; Fresh or N/S; Fried95001320, 120, 1, 0.00%, Cranberry, juice-Uncooked; Frozen; Cook Meth N/S 8001480, 212, 1, 0.00%, Eggplant-Cooked; Fresh or N/S; Boiled21000490, 213, 1, 0.00%, Beef, liver-Cooked; Fresh or N/S; Fried 4013550, 222, 1, 0.00%, Spinach-Cooked; Frozen; Boiled21000470, 221, 1, 0.00%, Beef, fat-Cooked; Frozen; Baked 6003480, 230, 1, 0.00%, Soybean, flour-Cooked; Dried; Cook Meth N/S27002220, 215, 1, 0.00%, Milk, fat-Cooked; Fresh or N/S; Boiled/baked 6032560, 212, 1, 0.00%, Pea, dry-Cooked; Fresh or N/S; Boiled 8003770, 215, 1, 0.00%, Tomato, puree-Cooked; Fresh or N/S; Boiled/baked 8003760, 242, 1, 0.00%, Tomato, paste-Cooked; Canned; Boiled 1010500, 250, 1, 0.00%, Beet, garden, roots-Cooked; Cured etc; Cook MethN/S21000490, 214, 1, 0.00%, Beef, liver-Cooked; Fresh or N/S; Fried/baked 1033660, 210, 1, 0.00%, Sweet potato-Cooked; Fresh or N/S; Cook Meth N/S15003250, 210, 1, 0.00%, Rice, flour-Cooked; Fresh or N/S; Cook Meth N/S 6030380, 232, 1, 0.00%, Bean, lima, seed-Cooked; Dried; Boiled 6030420, 232, 1, 0.00%, Bean, pinto, seed-Cooked; Dried; Boiled15001240, 210, 1, 0.00%, Corn, field, syrup-Cooked; Fresh or N/S; Cook MethN/S

426

Females 13-49 yrsLow percentile for CEC records: 95 Exposure (mg/day) = 0.000325High percentile for CEC records: 100 Exposure (mg/day) = 0.037516Number of actual records in this interval: 5541

Critical foods/foodforms for this population (as derived from these records): N=number of appearances in all records (including duplicates) %=percent of total exposure for all records (including duplicates)

Food, FF, N , Percent, Food Name --------, ---, -----, -------, -------------12002880, 110, 154, 7.90%, Plum, prune, juice-Uncooked; Fresh or N/S; CookMeth N/S 5022290, 212, 155, 7.45%, Mustard greens-Cooked; Fresh or N/S; Boiled 8002720, 110, 561, 7.20%, Pepper, nonbell-Uncooked; Fresh or N/S; Cook MethN/S10002000, 110, 938, 7.19%, Lemon, juice-Uncooked; Fresh or N/S; Cook Meth N/S 4023220, 240, 19, 5.31%, Rhubarb-Cooked; Canned; Cook Meth N/S10001810, 110, 568, 4.62%, Grapefruit, juice-Uncooked; Fresh or N/S; Cook MethN/S95002810, 110, 449, 3.70%, Pineapple, juice-Uncooked; Fresh or N/S; Cook MethN/S 5020700, 150, 152, 3.24%, Cabbage, Chinese, bok choy-Uncooked; Cured etc;Cook Meth N/S10002070, 110, 425, 2.56%, Lime, juice-Uncooked; Fresh or N/S; Cook Meth N/S13020570, 110, 44, 2.51%, Blueberry-Uncooked; Fresh or N/S; Cook Meth N/S 8002720, 213, 229, 2.48%, Pepper, nonbell-Cooked; Fresh or N/S; Fried12002620, 110, 114, 2.33%, Peach, juice-Uncooked; Fresh or N/S; Cook Meth N/S 5020700, 210, 134, 2.28%, Cabbage, Chinese, bok choy-Cooked; Fresh or N/S;Cook Meth N/S 8002340, 210, 190, 2.27%, Okra-Cooked; Fresh or N/S; Cook Meth N/S 8002720, 212, 215, 2.20%, Pepper, nonbell-Cooked; Fresh or N/S; Boiled 4023220, 211, 57, 2.19%, Rhubarb-Cooked; Fresh or N/S; Baked11000070, 110, 126, 1.69%, Apple, fruit with peel-Uncooked; Fresh or N/S; CookMeth N/S 8002340, 220, 95, 1.54%, Okra-Cooked; Frozen; Cook Meth N/S 5022290, 242, 19, 1.53%, Mustard greens-Cooked; Canned; Boiled 8002720, 210, 377, 1.35%, Pepper, nonbell-Cooked; Fresh or N/S; Cook Meth N/S95002350, 240, 48, 1.27%, Olive-Cooked; Canned; Cook Meth N/S13010580, 110, 95, 1.15%, Boysenberry-Uncooked; Fresh or N/S; Cook Meth N/S12000910, 210, 159, 1.08%, Cherry, juice-Cooked; Fresh or N/S; Cook Meth N/S13013200, 240, 82, 1.00%, Raspberry-Cooked; Canned; Cook Meth N/S10003690, 110, 149, 0.91%, Tangerine-Uncooked; Fresh or N/S; Cook Meth N/S 8002340, 213, 117, 0.91%, Okra-Cooked; Fresh or N/S; Fried13020570, 211, 68, 0.91%, Blueberry-Cooked; Fresh or N/S; Baked12000910, 110, 95, 0.87%, Cherry, juice-Uncooked; Fresh or N/S; Cook Meth N/S95001750, 110, 65, 0.74%, Grape-Uncooked; Fresh or N/S; Cook Meth N/S 4020860, 110, 19, 0.74%, Celery, juice-Uncooked; Fresh or N/S; Cook Meth N/S 8002700, 110, 83, 0.65%, Pepper, bell-Uncooked; Fresh or N/S; Cook Meth N/S10001810, 120, 115, 0.64%, Grapefruit, juice-Uncooked; Frozen; Cook Meth N/S 8002720, 150, 109, 0.57%, Pepper, nonbell-Uncooked; Cured etc; Cook Meth N/S10002000, 240, 347, 0.56%, Lemon, juice-Cooked; Canned; Cook Meth N/S 8002700, 210, 74, 0.54%, Pepper, bell-Cooked; Fresh or N/S; Cook Meth N/S10002000, 130, 123, 0.53%, Lemon, juice-Uncooked; Dried; Cook Meth N/S 8002720, 240, 434, 0.51%, Pepper, nonbell-Cooked; Canned; Cook Meth N/S11000090, 211, 157, 0.43%, Apple, dried-Cooked; Fresh or N/S; Baked10001810, 240, 254, 0.43%, Grapefruit, juice-Cooked; Canned; Cook Meth N/S12002600, 110, 42, 0.40%, Peach-Uncooked; Fresh or N/S; Cook Meth N/S12002620, 240, 38, 0.37%, Peach, juice-Cooked; Canned; Cook Meth N/S10003700, 110, 95, 0.35%, Tangerine, juice-Uncooked; Fresh or N/S; Cook MethN/S 8002720, 220, 38, 0.35%, Pepper, nonbell-Cooked; Frozen; Cook Meth N/S13013200, 110, 22, 0.33%, Raspberry-Uncooked; Fresh or N/S; Cook Meth N/S12002300, 110, 22, 0.31%, Nectarine-Uncooked; Fresh or N/S; Cook Meth N/S

427

13021360, 110, 19, 0.29%, Currant-Uncooked; Fresh or N/S; Cook Meth N/S10003700, 240, 227, 0.28%, Tangerine, juice-Cooked; Canned; Cook Meth N/S10001990, 110, 208, 0.27%, Lemon-Uncooked; Fresh or N/S; Cook Meth N/S10002000, 210, 182, 0.25%, Lemon, juice-Cooked; Fresh or N/S; Cook Meth N/S 8002340, 240, 19, 0.25%, Okra-Cooked; Canned; Cook Meth N/S 8002720, 221, 26, 0.23%, Pepper, nonbell-Cooked; Frozen; Baked 5020700, 110, 19, 0.23%, Cabbage, Chinese, bok choy-Uncooked; Fresh or N/S;Cook Meth N/S10002070, 240, 206, 0.22%, Lime, juice-Cooked; Canned; Cook Meth N/S10002060, 110, 77, 0.22%, Lime-Uncooked; Fresh or N/S; Cook Meth N/S12002610, 130, 19, 0.22%, Peach, dried-Uncooked; Dried; Cook Meth N/S25002930, 210, 634, 0.21%, Pork, fat-Cooked; Fresh or N/S; Cook Meth N/S95002350, 211, 23, 0.21%, Olive-Cooked; Fresh or N/S; Baked95003590, 110, 25, 0.21%, Strawberry-Uncooked; Fresh or N/S; Cook Meth N/S12002600, 240, 36, 0.20%, Peach-Cooked; Canned; Cook Meth N/S13010580, 240, 161, 0.20%, Boysenberry-Cooked; Canned; Cook Meth N/S12000910, 240, 126, 0.20%, Cherry, juice-Cooked; Canned; Cook Meth N/S 9020880, 210, 19, 0.18%, Chayote, fruit-Cooked; Fresh or N/S; Cook Meth N/S13020570, 240, 12, 0.18%, Blueberry-Cooked; Canned; Cook Meth N/S13010550, 211, 4, 0.18%, Blackberry-Cooked; Fresh or N/S; Baked11002660, 110, 16, 0.18%, Pear-Uncooked; Fresh or N/S; Cook Meth N/S13010550, 240, 51, 0.18%, Blackberry-Cooked; Canned; Cook Meth N/S15001240, 240, 989, 0.17%, Corn, field, syrup-Cooked; Canned; Cook Meth N/S11000080, 211, 12, 0.17%, Apple, peeled fruit-Cooked; Fresh or N/S; Baked13020570, 214, 5, 0.16%, Blueberry-Cooked; Fresh or N/S; Fried/baked11000100, 110, 157, 0.14%, Apple, juice-Uncooked; Fresh or N/S; Cook Meth N/S10001070, 110, 19, 0.12%, Citrus hybrids-Uncooked; Fresh or N/S; Cook MethN/S13020570, 120, 10, 0.12%, Blueberry-Uncooked; Frozen; Cook Meth N/S10002000, 211, 154, 0.11%, Lemon, juice-Cooked; Fresh or N/S; Baked25002930, 213, 215, 0.11%, Pork, fat-Cooked; Fresh or N/S; Fried13010580, 120, 63, 0.10%, Boysenberry-Uncooked; Frozen; Cook Meth N/S13010550, 110, 9, 0.10%, Blackberry-Uncooked; Fresh or N/S; Cook Meth N/S15001240, 110, 544, 0.10%, Corn, field, syrup-Uncooked; Fresh or N/S; CookMeth N/S95002810, 240, 150, 0.10%, Pineapple, juice-Cooked; Canned; Cook Meth N/S95002360, 900, 169, 0.10%, Olive, oil-Refined; FF N/A; Cook Meth N/S95000730, 110, 57, 0.10%, Cactus-Uncooked; Fresh or N/S; Cook Meth N/S12000900, 110, 13, 0.09%, Cherry-Uncooked; Fresh or N/S; Cook Meth N/S25002930, 250, 317, 0.09%, Pork, fat-Cooked; Cured etc; Cook Meth N/S 6010430, 242, 9, 0.08%, Bean, snap, succulent-Cooked; Canned; Boiled25002930, 211, 283, 0.08%, Pork, fat-Cooked; Fresh or N/S; Baked10002410, 110, 269, 0.08%, Orange, juice-Uncooked; Fresh or N/S; Cook Meth N/S15004020, 211, 568, 0.07%, Wheat, flour-Cooked; Fresh or N/S; Baked10002070, 120, 84, 0.07%, Lime, juice-Uncooked; Frozen; Cook Meth N/S25002930, 230, 162, 0.07%, Pork, fat-Cooked; Dried; Cook Meth N/S12000900, 211, 9, 0.06%, Cherry-Cooked; Fresh or N/S; Baked 8002700, 213, 17, 0.06%, Pepper, bell-Cooked; Fresh or N/S; Fried 8002730, 212, 114, 0.06%, Pepper, nonbell, dried-Cooked; Fresh or N/S; Boiled13010550, 120, 6, 0.06%, Blackberry-Uncooked; Frozen; Cook Meth N/S 4011500, 110, 110, 0.06%, Endive-Uncooked; Fresh or N/S; Cook Meth N/S10002410, 120, 199, 0.06%, Orange, juice-Uncooked; Frozen; Cook Meth N/S11000090, 130, 19, 0.06%, Apple, dried-Uncooked; Dried; Cook Meth N/S10002000, 212, 38, 0.06%, Lemon, juice-Cooked; Fresh or N/S; Boiled21000440, 210, 321, 0.06%, Beef, meat-Cooked; Fresh or N/S; Cook Meth N/S11002670, 130, 19, 0.06%, Pear, dried-Uncooked; Dried; Cook Meth N/S 8003770, 210, 129, 0.05%, Tomato, puree-Cooked; Fresh or N/S; Cook Meth N/S10003700, 120, 60, 0.05%, Tangerine, juice-Uncooked; Frozen; Cook Meth N/S 8002730, 210, 167, 0.05%, Pepper, nonbell, dried-Cooked; Fresh or N/S; CookMeth N/S 8002730, 211, 38, 0.05%, Pepper, nonbell, dried-Cooked; Fresh or N/S; Baked13013210, 110, 11, 0.05%, Raspberry, juice-Uncooked; Fresh or N/S; Cook MethN/S 9010750, 110, 11, 0.05%, Cantaloupe-Uncooked; Fresh or N/S; Cook Meth N/S13020570, 213, 5, 0.05%, Blueberry-Cooked; Fresh or N/S; Fried

428

25002900, 250, 169, 0.05%, Pork, meat-Cooked; Cured etc; Cook Meth N/S10002000, 120, 60, 0.04%, Lemon, juice-Uncooked; Frozen; Cook Meth N/S27002220, 110, 306, 0.04%, Milk, fat-Uncooked; Fresh or N/S; Cook Meth N/S25002930, 232, 59, 0.04%, Pork, fat-Cooked; Dried; Boiled 8002720, 230, 38, 0.04%, Pepper, nonbell-Cooked; Dried; Cook Meth N/S15004020, 232, 86, 0.04%, Wheat, flour-Cooked; Dried; Boiled 8002340, 242, 19, 0.04%, Okra-Cooked; Canned; Boiled15003250, 230, 69, 0.04%, Rice, flour-Cooked; Dried; Cook Meth N/S13013200, 211, 12, 0.03%, Raspberry-Cooked; Fresh or N/S; Baked12000910, 120, 60, 0.03%, Cherry, juice-Uncooked; Frozen; Cook Meth N/S21000470, 210, 153, 0.03%, Beef, fat-Cooked; Fresh or N/S; Cook Meth N/S12002600, 211, 4, 0.03%, Peach-Cooked; Fresh or N/S; Baked95001760, 110, 34, 0.03%, Grape, juice-Uncooked; Fresh or N/S; Cook Meth N/S 9021350, 110, 33, 0.03%, Cucumber-Uncooked; Fresh or N/S; Cook Meth N/S 6010430, 212, 3, 0.03%, Bean, snap, succulent-Cooked; Fresh or N/S; Boiled25002900, 210, 110, 0.03%, Pork, meat-Cooked; Fresh or N/S; Cook Meth N/S13020570, 210, 3, 0.03%, Blueberry-Cooked; Fresh or N/S; Cook Meth N/S12000130, 211, 5, 0.03%, Apricot, dried-Cooked; Fresh or N/S; Baked15003250, 210, 77, 0.03%, Rice, flour-Cooked; Fresh or N/S; Cook Meth N/S95002800, 130, 19, 0.03%, Pineapple, dried-Uncooked; Dried; Cook Meth N/S25002930, 253, 111, 0.03%, Pork, fat-Cooked; Cured etc; Fried15003250, 232, 38, 0.02%, Rice, flour-Cooked; Dried; Boiled21000440, 213, 166, 0.02%, Beef, meat-Cooked; Fresh or N/S; Fried95003600, 110, 5, 0.02%, Strawberry, juice-Uncooked; Fresh or N/S; Cook MethN/S10002400, 110, 8, 0.02%, Orange-Uncooked; Fresh or N/S; Cook Meth N/S13013210, 240, 14, 0.02%, Raspberry, juice-Cooked; Canned; Cook Meth N/S21000440, 211, 111, 0.02%, Beef, meat-Cooked; Fresh or N/S; Baked 8002730, 240, 67, 0.02%, Pepper, nonbell, dried-Cooked; Canned; Cook MethN/S15001210, 233, 132, 0.02%, Corn, field, meal-Cooked; Dried; Fried15001240, 130, 83, 0.02%, Corn, field, syrup-Uncooked; Dried; Cook Meth N/S25002900, 211, 73, 0.02%, Pork, meat-Cooked; Fresh or N/S; Baked15001200, 214, 106, 0.02%, Corn, field, flour-Cooked; Fresh or N/S;Fried/baked21000470, 213, 126, 0.02%, Beef, fat-Cooked; Fresh or N/S; Fried 8002700, 221, 4, 0.02%, Pepper, bell-Cooked; Frozen; Baked12000120, 110, 3, 0.02%, Apricot-Uncooked; Fresh or N/S; Cook Meth N/S15003250, 212, 19, 0.02%, Rice, flour-Cooked; Fresh or N/S; Boiled 2001010, 110, 83, 0.02%, Chicory, tops-Uncooked; Fresh or N/S; Cook Meth N/S95001750, 210, 7, 0.02%, Grape-Cooked; Fresh or N/S; Cook Meth N/S25002900, 213, 89, 0.02%, Pork, meat-Cooked; Fresh or N/S; Fried 9014000, 110, 19, 0.02%, Watermelon, juice-Uncooked; Fresh or N/S; Cook MethN/S95002810, 120, 58, 0.02%, Pineapple, juice-Uncooked; Frozen; Cook Meth N/S95003600, 240, 6, 0.02%, Strawberry, juice-Cooked; Canned; Cook Meth N/S 8002700, 211, 16, 0.01%, Pepper, bell-Cooked; Fresh or N/S; Baked 4012480, 110, 20, 0.01%, Parsley, leaves-Uncooked; Fresh or N/S; Cook MethN/S11000110, 212, 27, 0.01%, Apple, sauce-Cooked; Fresh or N/S; Boiled11002660, 240, 2, 0.01%, Pear-Cooked; Canned; Cook Meth N/S 8002720, 211, 41, 0.01%, Pepper, nonbell-Cooked; Fresh or N/S; Baked15004020, 210, 119, 0.01%, Wheat, flour-Cooked; Fresh or N/S; Cook Meth N/S25002930, 212, 26, 0.01%, Pork, fat-Cooked; Fresh or N/S; Boiled95003590, 240, 8, 0.01%, Strawberry-Cooked; Canned; Cook Meth N/S12000120, 240, 7, 0.01%, Apricot-Cooked; Canned; Cook Meth N/S95002350, 210, 2, 0.01%, Olive-Cooked; Fresh or N/S; Cook Meth N/S95002350, 221, 2, 0.01%, Olive-Cooked; Frozen; Baked 8003790, 110, 23, 0.01%, Tomato, juice-Uncooked; Fresh or N/S; Cook Meth N/S27002220, 120, 80, 0.01%, Milk, fat-Uncooked; Frozen; Cook Meth N/S13013200, 120, 5, 0.01%, Raspberry-Uncooked; Frozen; Cook Meth N/S 8003760, 210, 19, 0.01%, Tomato, paste-Cooked; Fresh or N/S; Cook Meth N/S 8002340, 212, 2, 0.01%, Okra-Cooked; Fresh or N/S; Boiled12000130, 130, 3, 0.01%, Apricot, dried-Uncooked; Dried; Cook Meth N/S 8003790, 240, 26, 0.01%, Tomato, juice-Cooked; Canned; Cook Meth N/S

429

8002720, 215, 48, 0.01%, Pepper, nonbell-Cooked; Fresh or N/S; Boiled/baked95001750, 240, 7, 0.01%, Grape-Cooked; Canned; Cook Meth N/S95003590, 120, 2, 0.01%, Strawberry-Uncooked; Frozen; Cook Meth N/S 8003770, 212, 43, 0.01%, Tomato, puree-Cooked; Fresh or N/S; Boiled 4012480, 212, 19, 0.01%, Parsley, leaves-Cooked; Fresh or N/S; Boiled11000080, 221, 2, 0.01%, Apple, peeled fruit-Cooked; Frozen; Baked21000440, 212, 50, 0.01%, Beef, meat-Cooked; Fresh or N/S; Boiled13010560, 110, 1, 0.01%, Blackberry, juice-Uncooked; Fresh or N/S; Cook MethN/S15001200, 230, 67, 0.01%, Corn, field, flour-Cooked; Dried; Cook Meth N/S10002000, 232, 20, 0.01%, Lemon, juice-Cooked; Dried; Boiled 9021350, 240, 23, 0.01%, Cucumber-Cooked; Canned; Cook Meth N/S 8002720, 232, 20, 0.01%, Pepper, nonbell-Cooked; Dried; Boiled95001320, 240, 27, 0.01%, Cranberry, juice-Cooked; Canned; Cook Meth N/S 6010430, 222, 1, 0.01%, Bean, snap, succulent-Cooked; Frozen; Boiled27002220, 232, 20, 0.01%, Milk, fat-Cooked; Dried; Boiled14002820, 211, 21, 0.01%, Pistachio-Cooked; Fresh or N/S; Baked15001210, 230, 58, 0.01%, Corn, field, meal-Cooked; Dried; Cook Meth N/S 8001480, 214, 1, 0.01%, Eggplant-Cooked; Fresh or N/S; Fried/baked 4012480, 210, 39, 0.01%, Parsley, leaves-Cooked; Fresh or N/S; Cook Meth N/S 8002700, 150, 9, 0.01%, Pepper, bell-Uncooked; Cured etc; Cook Meth N/S 8002700, 215, 7, 0.01%, Pepper, bell-Cooked; Fresh or N/S; Boiled/baked13013210, 120, 8, 0.01%, Raspberry, juice-Uncooked; Frozen; Cook Meth N/S95003600, 210, 3, 0.01%, Strawberry, juice-Cooked; Fresh or N/S; Cook MethN/S19011440, 240, 38, 0.01%, Dillweed-Cooked; Canned; Cook Meth N/S 8003770, 240, 28, 0.01%, Tomato, puree-Cooked; Canned; Cook Meth N/S21000440, 250, 20, 0.01%, Beef, meat-Cooked; Cured etc; Cook Meth N/S12000900, 240, 3, 0.01%, Cherry-Cooked; Canned; Cook Meth N/S21000470, 250, 21, 0.01%, Beef, fat-Cooked; Cured etc; Cook Meth N/S95001760, 240, 22, 0.01%, Grape, juice-Cooked; Canned; Cook Meth N/S21000470, 211, 42, 0.01%, Beef, fat-Cooked; Fresh or N/S; Baked95002790, 240, 9, 0.01%, Pineapple-Cooked; Canned; Cook Meth N/S10002410, 240, 22, 0.00%, Orange, juice-Cooked; Canned; Cook Meth N/S 9023080, 211, 24, 0.00%, Pumpkin-Cooked; Fresh or N/S; Baked95002350, 232, 1, 0.00%, Olive-Cooked; Dried; Boiled15001200, 232, 19, 0.00%, Corn, field, flour-Cooked; Dried; Boiled15003240, 232, 39, 0.00%, Rice, brown-Cooked; Dried; Boiled15001260, 230, 42, 0.00%, Corn, pop-Cooked; Dried; Cook Meth N/S12002850, 110, 3, 0.00%, Plum-Uncooked; Fresh or N/S; Cook Meth N/S95002350, 212, 1, 0.00%, Olive-Cooked; Fresh or N/S; Boiled12000900, 210, 1, 0.00%, Cherry-Cooked; Fresh or N/S; Cook Meth N/S 1033000, 212, 13, 0.00%, Potato, tuber, w/o peel-Cooked; Fresh or N/S;Boiled15004010, 230, 45, 0.00%, Wheat, grain-Cooked; Dried; Cook Meth N/S 8003740, 210, 26, 0.00%, Tomatillo-Cooked; Fresh or N/S; Cook Meth N/S 6003490, 210, 27, 0.00%, Soybean, soy milk-Cooked; Fresh or N/S; Cook MethN/S 8003790, 212, 24, 0.00%, Tomato, juice-Cooked; Fresh or N/S; Boiled95001790, 110, 16, 0.00%, Grape, wine and sherry-Uncooked; Fresh or N/S; CookMeth N/S 6030420, 232, 21, 0.00%, Bean, pinto, seed-Cooked; Dried; Boiled 1033660, 212, 14, 0.00%, Sweet potato-Cooked; Fresh or N/S; Boiled95002630, 112, 19, 0.00%, Peanut-Uncooked; Fresh or N/S; Boiled11000070, 211, 2, 0.00%, Apple, fruit with peel-Cooked; Fresh or N/S; Baked 8003750, 240, 17, 0.00%, Tomato-Cooked; Canned; Cook Meth N/S11002660, 210, 4, 0.00%, Pear-Cooked; Fresh or N/S; Cook Meth N/S95002640, 210, 21, 0.00%, Peanut, butter-Cooked; Fresh or N/S; Cook Meth N/S11000090, 230, 5, 0.00%, Apple, dried-Cooked; Dried; Cook Meth N/S11000100, 240, 7, 0.00%, Apple, juice-Cooked; Canned; Cook Meth N/S15001200, 211, 20, 0.00%, Corn, field, flour-Cooked; Fresh or N/S; Baked20003640, 211, 19, 0.00%, Sunflower, seed-Cooked; Fresh or N/S; Baked 6032030, 232, 19, 0.00%, Lentil, seed-Cooked; Dried; Boiled 1033660, 211, 8, 0.00%, Sweet potato-Cooked; Fresh or N/S; Baked25002900, 212, 20, 0.00%, Pork, meat-Cooked; Fresh or N/S; Boiled

430

27002220, 211, 25, 0.00%, Milk, fat-Cooked; Fresh or N/S; Baked 5010690, 110, 20, 0.00%, Cabbage-Uncooked; Fresh or N/S; Cook Meth N/S27002220, 230, 18, 0.00%, Milk, fat-Cooked; Dried; Cook Meth N/S15001200, 210, 23, 0.00%, Corn, field, flour-Cooked; Fresh or N/S; Cook MethN/S27002220, 215, 19, 0.00%, Milk, fat-Cooked; Fresh or N/S; Boiled/baked 8002730, 213, 20, 0.00%, Pepper, nonbell, dried-Cooked; Fresh or N/S; Fried 8002720, 250, 19, 0.00%, Pepper, nonbell-Cooked; Cured etc; Cook Meth N/S21000440, 221, 19, 0.00%, Beef, meat-Cooked; Frozen; Baked11002680, 110, 4, 0.00%, Pear, juice-Uncooked; Fresh or N/S; Cook Meth N/S15004020, 215, 19, 0.00%, Wheat, flour-Cooked; Fresh or N/S; Boiled/baked15004020, 221, 18, 0.00%, Wheat, flour-Cooked; Frozen; Baked 6030410, 232, 19, 0.00%, Bean, pink, seed-Cooked; Dried; Boiled15001210, 211, 19, 0.00%, Corn, field, meal-Cooked; Fresh or N/S; Baked15004010, 232, 18, 0.00%, Wheat, grain-Cooked; Dried; Boiled10001800, 110, 7, 0.00%, Grapefruit-Uncooked; Fresh or N/S; Cook Meth N/S27002220, 210, 12, 0.00%, Milk, fat-Cooked; Fresh or N/S; Cook Meth N/S 9021020, 210, 2, 0.00%, Chinese waxgourd-Cooked; Fresh or N/S; Cook MethN/S 8002730, 221, 3, 0.00%, Pepper, nonbell, dried-Cooked; Frozen; Baked 8003750, 110, 9, 0.00%, Tomato-Uncooked; Fresh or N/S; Cook Meth N/S11000100, 210, 8, 0.00%, Apple, juice-Cooked; Fresh or N/S; Cook Meth N/S11002680, 120, 3, 0.00%, Pear, juice-Uncooked; Frozen; Cook Meth N/S 8001480, 210, 1, 0.00%, Eggplant-Cooked; Fresh or N/S; Cook Meth N/S21000470, 212, 8, 0.00%, Beef, fat-Cooked; Fresh or N/S; Boiled15003240, 210, 2, 0.00%, Rice, brown-Cooked; Fresh or N/S; Cook Meth N/S 8003750, 211, 7, 0.00%, Tomato-Cooked; Fresh or N/S; Baked14002690, 211, 4, 0.00%, Pecan-Cooked; Fresh or N/S; Baked 9021350, 150, 6, 0.00%, Cucumber-Uncooked; Cured etc; Cook Meth N/S12000140, 120, 1, 0.00%, Apricot, juice-Uncooked; Frozen; Cook Meth N/S20003640, 110, 2, 0.00%, Sunflower, seed-Uncooked; Fresh or N/S; Cook MethN/S 8003790, 210, 2, 0.00%, Tomato, juice-Cooked; Fresh or N/S; Cook Meth N/S11000090, 210, 2, 0.00%, Apple, dried-Cooked; Fresh or N/S; Cook Meth N/S 1032990, 212, 3, 0.00%, Potato, tuber, w/peel-Cooked; Fresh or N/S; Boiled95001320, 110, 2, 0.00%, Cranberry, juice-Uncooked; Fresh or N/S; Cook MethN/S 4020860, 240, 4, 0.00%, Celery, juice-Cooked; Canned; Cook Meth N/S15004020, 231, 3, 0.00%, Wheat, flour-Cooked; Dried; Baked12000900, 120, 3, 0.00%, Cherry-Uncooked; Frozen; Cook Meth N/S95003590, 211, 1, 0.00%, Strawberry-Cooked; Fresh or N/S; Baked 9011870, 110, 1, 0.00%, Honeydew melon-Uncooked; Fresh or N/S; Cook MethN/S 5010830, 212, 3, 0.00%, Cauliflower-Cooked; Fresh or N/S; Boiled21000450, 232, 1, 0.00%, Beef, meat, dried-Cooked; Dried; Boiled25002930, 214, 2, 0.00%, Pork, fat-Cooked; Fresh or N/S; Fried/baked 1032990, 211, 2, 0.00%, Potato, tuber, w/peel-Cooked; Fresh or N/S; Baked 8003750, 215, 3, 0.00%, Tomato-Cooked; Fresh or N/S; Boiled/baked95000190, 212, 2, 0.00%, Asparagus-Cooked; Fresh or N/S; Boiled15001270, 212, 1, 0.00%, Corn, sweet-Cooked; Fresh or N/S; Boiled15004020, 212, 3, 0.00%, Wheat, flour-Cooked; Fresh or N/S; Boiled15004010, 211, 3, 0.00%, Wheat, grain-Cooked; Fresh or N/S; Baked15001240, 230, 2, 0.00%, Corn, field, syrup-Cooked; Dried; Cook Meth N/S 8003750, 210, 3, 0.00%, Tomato-Cooked; Fresh or N/S; Cook Meth N/S95002630, 211, 1, 0.00%, Peanut-Cooked; Fresh or N/S; Baked15001240, 120, 2, 0.00%, Corn, field, syrup-Uncooked; Frozen; Cook Meth N/S 1010500, 250, 1, 0.00%, Beet, garden, roots-Cooked; Cured etc; Cook MethN/S 1033660, 210, 2, 0.00%, Sweet potato-Cooked; Fresh or N/S; Cook Meth N/S11000100, 120, 2, 0.00%, Apple, juice-Uncooked; Frozen; Cook Meth N/S95002810, 211, 1, 0.00%, Pineapple, juice-Cooked; Fresh or N/S; Baked15001200, 231, 2, 0.00%, Corn, field, flour-Cooked; Dried; Baked95001760, 210, 2, 0.00%, Grape, juice-Cooked; Fresh or N/S; Cook Meth N/S14003910, 211, 1, 0.00%, Walnut-Cooked; Fresh or N/S; Baked95000230, 110, 2, 0.00%, Banana-Uncooked; Fresh or N/S; Cook Meth N/S

431

6030420, 230, 2, 0.00%, Bean, pinto, seed-Cooked; Dried; Cook Meth N/S 9013990, 110, 1, 0.00%, Watermelon-Uncooked; Fresh or N/S; Cook Meth N/S10001060, 211, 1, 0.00%, Citrus citron-Cooked; Fresh or N/S; Baked 9023560, 212, 1, 0.00%, Squash, summer-Cooked; Fresh or N/S; Boiled 1033000, 211, 1, 0.00%, Potato, tuber, w/o peel-Cooked; Fresh or N/S; Baked15001200, 213, 1, 0.00%, Corn, field, flour-Cooked; Fresh or N/S; Fried11002680, 240, 1, 0.00%, Pear, juice-Cooked; Canned; Cook Meth N/S 1013140, 110, 1, 0.00%, Radish, roots-Uncooked; Fresh or N/S; Cook Meth N/S 1010780, 110, 1, 0.00%, Carrot-Uncooked; Fresh or N/S; Cook Meth N/S95003600, 120, 1, 0.00%, Strawberry, juice-Uncooked; Frozen; Cook Meth N/S12000140, 240, 1, 0.00%, Apricot, juice-Cooked; Canned; Cook Meth N/S26003390, 210, 1, 0.00%, Sheep, meat-Cooked; Fresh or N/S; Cook Meth N/S15004020, 214, 1, 0.00%, Wheat, flour-Cooked; Fresh or N/S; Fried/baked 8003750, 212, 1, 0.00%, Tomato-Cooked; Fresh or N/S; Boiled25002930, 222, 1, 0.00%, Pork, fat-Cooked; Frozen; Boiled15001210, 232, 1, 0.00%, Corn, field, meal-Cooked; Dried; Boiled12002600, 120, 1, 0.00%, Peach-Uncooked; Frozen; Cook Meth N/S10002010, 230, 1, 0.00%, Lemon, peel-Cooked; Dried; Cook Meth N/S15004020, 213, 1, 0.00%, Wheat, flour-Cooked; Fresh or N/S; Fried21000440, 214, 1, 0.00%, Beef, meat-Cooked; Fresh or N/S; Fried/baked 4012040, 110, 1, 0.00%, Lettuce, head-Uncooked; Fresh or N/S; Cook Meth N/S20003640, 230, 1, 0.00%, Sunflower, seed-Cooked; Dried; Cook Meth N/S

432

Custom demographics 1: Adults 16-70 yrLow percentile for CEC records: 95 Exposure (mg/day) = 0.000344High percentile for CEC records: 100 Exposure (mg/day) = 0.045247Number of actual records in this interval: 16591

Critical foods/foodforms for this population (as derived from these records): N=number of appearances in all records (including duplicates) %=percent of total exposure for all records (including duplicates)

Food, FF, N , Percent, Food Name --------, ---, -----, -------, ------------- 5022290, 212, 801, 10.10%, Mustard greens-Cooked; Fresh or N/S; Boiled 8002720, 110, 2543, 9.85%, Pepper, nonbell-Uncooked; Fresh or N/S; Cook MethN/S12002880, 110, 610, 7.72%, Plum, prune, juice-Uncooked; Fresh or N/S; CookMeth N/S10002000, 110, 2602, 5.10%, Lemon, juice-Uncooked; Fresh or N/S; Cook Meth N/S 4023220, 211, 342, 4.35%, Rhubarb-Cooked; Fresh or N/S; Baked10001810, 110, 1895, 4.27%, Grapefruit, juice-Uncooked; Fresh or N/S; Cook MethN/S 4023670, 212, 171, 3.78%, Swiss chard-Cooked; Fresh or N/S; Boiled 8002340, 210, 763, 3.66%, Okra-Cooked; Fresh or N/S; Cook Meth N/S 5020700, 150, 494, 3.51%, Cabbage, Chinese, bok choy-Uncooked; Cured etc;Cook Meth N/S 8002720, 210, 1550, 3.25%, Pepper, nonbell-Cooked; Fresh or N/S; Cook Meth N/S 4023220, 240, 57, 2.69%, Rhubarb-Cooked; Canned; Cook Meth N/S 5020700, 210, 522, 2.67%, Cabbage, Chinese, bok choy-Cooked; Fresh or N/S;Cook Meth N/S 4020860, 110, 133, 2.05%, Celery, juice-Uncooked; Fresh or N/S; Cook Meth N/S 8002720, 213, 597, 1.91%, Pepper, nonbell-Cooked; Fresh or N/S; Fried95002810, 110, 766, 1.57%, Pineapple, juice-Uncooked; Fresh or N/S; Cook MethN/S12002620, 110, 190, 1.51%, Peach, juice-Uncooked; Fresh or N/S; Cook Meth N/S10002070, 110, 782, 1.37%, Lime, juice-Uncooked; Fresh or N/S; Cook Meth N/S 8002720, 240, 1117, 1.33%, Pepper, nonbell-Cooked; Canned; Cook Meth N/S11000070, 110, 373, 1.25%, Apple, fruit with peel-Uncooked; Fresh or N/S; CookMeth N/S 8002340, 220, 247, 1.19%, Okra-Cooked; Frozen; Cook Meth N/S12002610, 130, 247, 1.18%, Peach, dried-Uncooked; Dried; Cook Meth N/S 5022290, 242, 96, 1.11%, Mustard greens-Cooked; Canned; Boiled13020570, 110, 93, 1.06%, Blueberry-Uncooked; Fresh or N/S; Cook Meth N/S 8002340, 213, 348, 1.06%, Okra-Cooked; Fresh or N/S; Fried13020570, 211, 175, 1.03%, Blueberry-Cooked; Fresh or N/S; Baked 8002720, 212, 480, 0.97%, Pepper, nonbell-Cooked; Fresh or N/S; Boiled12000910, 110, 233, 0.82%, Cherry, juice-Uncooked; Fresh or N/S; Cook Meth N/S95002350, 240, 122, 0.79%, Olive-Cooked; Canned; Cook Meth N/S12002620, 240, 136, 0.68%, Peach, juice-Cooked; Canned; Cook Meth N/S 8002720, 150, 409, 0.62%, Pepper, nonbell-Uncooked; Cured etc; Cook Meth N/S13013200, 240, 208, 0.57%, Raspberry-Cooked; Canned; Cook Meth N/S95001750, 110, 144, 0.54%, Grape-Uncooked; Fresh or N/S; Cook Meth N/S 8002700, 210, 241, 0.53%, Pepper, bell-Cooked; Fresh or N/S; Cook Meth N/S11000090, 211, 480, 0.53%, Apple, dried-Cooked; Fresh or N/S; Baked13010580, 120, 204, 0.49%, Boysenberry-Uncooked; Frozen; Cook Meth N/S10003690, 110, 360, 0.48%, Tangerine-Uncooked; Fresh or N/S; Cook Meth N/S10002000, 240, 829, 0.42%, Lemon, juice-Cooked; Canned; Cook Meth N/S 8002700, 110, 220, 0.39%, Pepper, bell-Uncooked; Fresh or N/S; Cook Meth N/S11000090, 130, 285, 0.39%, Apple, dried-Uncooked; Dried; Cook Meth N/S13010580, 110, 176, 0.37%, Boysenberry-Uncooked; Fresh or N/S; Cook Meth N/S 4023220, 120, 19, 0.36%, Rhubarb-Uncooked; Frozen; Cook Meth N/S12002600, 110, 116, 0.35%, Peach-Uncooked; Fresh or N/S; Cook Meth N/S 5022290, 222, 19, 0.35%, Mustard greens-Cooked; Frozen; Boiled10001810, 240, 588, 0.31%, Grapefruit, juice-Cooked; Canned; Cook Meth N/S 8002720, 220, 57, 0.29%, Pepper, nonbell-Cooked; Frozen; Cook Meth N/S

433

5020700, 110, 57, 0.28%, Cabbage, Chinese, bok choy-Uncooked; Fresh or N/S;Cook Meth N/S13013200, 120, 24, 0.26%, Raspberry-Uncooked; Frozen; Cook Meth N/S25002930, 210, 2008, 0.25%, Pork, fat-Cooked; Fresh or N/S; Cook Meth N/S95002350, 211, 76, 0.24%, Olive-Cooked; Fresh or N/S; Baked13013200, 110, 57, 0.23%, Raspberry-Uncooked; Fresh or N/S; Cook Meth N/S10002000, 130, 165, 0.22%, Lemon, juice-Uncooked; Dried; Cook Meth N/S10001810, 120, 156, 0.22%, Grapefruit, juice-Uncooked; Frozen; Cook Meth N/S12002300, 110, 48, 0.21%, Nectarine-Uncooked; Fresh or N/S; Cook Meth N/S12002600, 240, 89, 0.19%, Peach-Cooked; Canned; Cook Meth N/S 9010800, 110, 38, 0.18%, Casaba-Uncooked; Fresh or N/S; Cook Meth N/S11002660, 110, 69, 0.18%, Pear-Uncooked; Fresh or N/S; Cook Meth N/S95002800, 130, 266, 0.18%, Pineapple, dried-Uncooked; Dried; Cook Meth N/S12000910, 210, 89, 0.17%, Cherry, juice-Cooked; Fresh or N/S; Cook Meth N/S10003700, 240, 543, 0.17%, Tangerine, juice-Cooked; Canned; Cook Meth N/S11002670, 130, 228, 0.17%, Pear, dried-Uncooked; Dried; Cook Meth N/S10003700, 110, 214, 0.16%, Tangerine, juice-Uncooked; Fresh or N/S; Cook MethN/S 8002720, 221, 83, 0.16%, Pepper, nonbell-Cooked; Frozen; Baked 8002340, 150, 59, 0.14%, Okra-Uncooked; Cured etc; Cook Meth N/S13021360, 110, 38, 0.14%, Currant-Uncooked; Fresh or N/S; Cook Meth N/S10002070, 240, 521, 0.14%, Lime, juice-Cooked; Canned; Cook Meth N/S13010550, 240, 125, 0.13%, Blackberry-Cooked; Canned; Cook Meth N/S13021370, 130, 19, 0.13%, Currant, dried-Uncooked; Dried; Cook Meth N/S25002930, 213, 878, 0.12%, Pork, fat-Cooked; Fresh or N/S; Fried15001240, 240, 2256, 0.12%, Corn, field, syrup-Cooked; Canned; Cook Meth N/S13010550, 211, 16, 0.12%, Blackberry-Cooked; Fresh or N/S; Baked12000900, 110, 55, 0.11%, Cherry-Uncooked; Fresh or N/S; Cook Meth N/S 9020880, 210, 38, 0.10%, Chayote, fruit-Cooked; Fresh or N/S; Cook Meth N/S 8002340, 240, 38, 0.10%, Okra-Cooked; Canned; Cook Meth N/S13010580, 240, 415, 0.10%, Boysenberry-Cooked; Canned; Cook Meth N/S95003590, 110, 49, 0.09%, Strawberry-Uncooked; Fresh or N/S; Cook Meth N/S10002000, 211, 634, 0.09%, Lemon, juice-Cooked; Fresh or N/S; Baked10001990, 110, 389, 0.09%, Lemon-Uncooked; Fresh or N/S; Cook Meth N/S25002930, 211, 761, 0.09%, Pork, fat-Cooked; Fresh or N/S; Baked12002610, 230, 38, 0.08%, Peach, dried-Cooked; Dried; Cook Meth N/S25002930, 230, 560, 0.08%, Pork, fat-Cooked; Dried; Cook Meth N/S10002000, 120, 164, 0.08%, Lemon, juice-Uncooked; Frozen; Cook Meth N/S95002810, 240, 378, 0.08%, Pineapple, juice-Cooked; Canned; Cook Meth N/S12000900, 211, 38, 0.08%, Cherry-Cooked; Fresh or N/S; Baked10002000, 210, 209, 0.08%, Lemon, juice-Cooked; Fresh or N/S; Cook Meth N/S10002410, 110, 831, 0.08%, Orange, juice-Uncooked; Fresh or N/S; Cook Meth N/S11000080, 211, 23, 0.07%, Apple, peeled fruit-Cooked; Fresh or N/S; Baked10001070, 110, 38, 0.07%, Citrus hybrids-Uncooked; Fresh or N/S; Cook MethN/S15001240, 110, 1292, 0.07%, Corn, field, syrup-Uncooked; Fresh or N/S; CookMeth N/S25002930, 253, 499, 0.07%, Pork, fat-Cooked; Cured etc; Fried 8002730, 211, 103, 0.07%, Pepper, nonbell, dried-Cooked; Fresh or N/S; Baked12000910, 240, 200, 0.07%, Cherry, juice-Cooked; Canned; Cook Meth N/S25002930, 250, 839, 0.06%, Pork, fat-Cooked; Cured etc; Cook Meth N/S 8002730, 212, 314, 0.06%, Pepper, nonbell, dried-Cooked; Fresh or N/S; Boiled10002060, 110, 79, 0.06%, Lime-Uncooked; Fresh or N/S; Cook Meth N/S11000090, 230, 49, 0.06%, Apple, dried-Cooked; Dried; Cook Meth N/S13020570, 120, 22, 0.06%, Blueberry-Uncooked; Frozen; Cook Meth N/S13013210, 110, 27, 0.06%, Raspberry, juice-Uncooked; Fresh or N/S; Cook MethN/S12002600, 211, 20, 0.05%, Peach-Cooked; Fresh or N/S; Baked13020570, 240, 17, 0.05%, Blueberry-Cooked; Canned; Cook Meth N/S95002360, 900, 336, 0.05%, Olive, oil-Refined; FF N/A; Cook Meth N/S13020570, 213, 14, 0.05%, Blueberry-Cooked; Fresh or N/S; Fried13020570, 214, 6, 0.05%, Blueberry-Cooked; Fresh or N/S; Fried/baked 6010430, 242, 20, 0.05%, Bean, snap, succulent-Cooked; Canned; Boiled15004020, 211, 1173, 0.05%, Wheat, flour-Cooked; Fresh or N/S; Baked11000100, 110, 157, 0.05%, Apple, juice-Uncooked; Fresh or N/S; Cook Meth N/S

434

9020210, 212, 19, 0.05%, Balsam pear-Cooked; Fresh or N/S; Boiled 8002700, 213, 41, 0.04%, Pepper, bell-Cooked; Fresh or N/S; Fried 2001400, 212, 19, 0.04%, Dasheen, leaves-Cooked; Fresh or N/S; Boiled 4011500, 110, 283, 0.04%, Endive-Uncooked; Fresh or N/S; Cook Meth N/S25002900, 210, 554, 0.04%, Pork, meat-Cooked; Fresh or N/S; Cook Meth N/S95001760, 110, 194, 0.04%, Grape, juice-Uncooked; Fresh or N/S; Cook Meth N/S15001200, 214, 488, 0.04%, Corn, field, flour-Cooked; Fresh or N/S;Fried/baked13010550, 110, 21, 0.03%, Blackberry-Uncooked; Fresh or N/S; Cook Meth N/S10002070, 120, 181, 0.03%, Lime, juice-Uncooked; Frozen; Cook Meth N/S27002220, 110, 755, 0.03%, Milk, fat-Uncooked; Fresh or N/S; Cook Meth N/S21000440, 210, 714, 0.03%, Beef, meat-Cooked; Fresh or N/S; Cook Meth N/S 9010750, 110, 47, 0.03%, Cantaloupe-Uncooked; Fresh or N/S; Cook Meth N/S21000440, 211, 467, 0.03%, Beef, meat-Cooked; Fresh or N/S; Baked95002810, 120, 120, 0.03%, Pineapple, juice-Uncooked; Frozen; Cook Meth N/S15003250, 230, 200, 0.03%, Rice, flour-Cooked; Dried; Cook Meth N/S13013200, 211, 30, 0.03%, Raspberry-Cooked; Fresh or N/S; Baked25002900, 250, 493, 0.03%, Pork, meat-Cooked; Cured etc; Cook Meth N/S25002930, 232, 201, 0.03%, Pork, fat-Cooked; Dried; Boiled10002410, 120, 327, 0.03%, Orange, juice-Uncooked; Frozen; Cook Meth N/S10003700, 120, 143, 0.03%, Tangerine, juice-Uncooked; Frozen; Cook Meth N/S21000470, 210, 540, 0.03%, Beef, fat-Cooked; Fresh or N/S; Cook Meth N/S95000730, 110, 57, 0.03%, Cactus-Uncooked; Fresh or N/S; Cook Meth N/S12002600, 120, 8, 0.03%, Peach-Uncooked; Frozen; Cook Meth N/S25002900, 211, 313, 0.03%, Pork, meat-Cooked; Fresh or N/S; Baked 8002700, 150, 34, 0.03%, Pepper, bell-Uncooked; Cured etc; Cook Meth N/S 6010430, 212, 13, 0.02%, Bean, snap, succulent-Cooked; Fresh or N/S; Boiled13020570, 210, 9, 0.02%, Blueberry-Cooked; Fresh or N/S; Cook Meth N/S 8003770, 210, 302, 0.02%, Tomato, puree-Cooked; Fresh or N/S; Cook Meth N/S 8002340, 212, 60, 0.02%, Okra-Cooked; Fresh or N/S; Boiled21000440, 213, 468, 0.02%, Beef, meat-Cooked; Fresh or N/S; Fried12000120, 240, 23, 0.02%, Apricot-Cooked; Canned; Cook Meth N/S12000130, 211, 12, 0.02%, Apricot, dried-Cooked; Fresh or N/S; Baked 8002700, 211, 50, 0.02%, Pepper, bell-Cooked; Fresh or N/S; Baked11002660, 240, 9, 0.02%, Pear-Cooked; Canned; Cook Meth N/S 9021350, 110, 108, 0.02%, Cucumber-Uncooked; Fresh or N/S; Cook Meth N/S 8002720, 211, 130, 0.02%, Pepper, nonbell-Cooked; Fresh or N/S; Baked21000470, 213, 365, 0.02%, Beef, fat-Cooked; Fresh or N/S; Fried10002000, 212, 46, 0.02%, Lemon, juice-Cooked; Fresh or N/S; Boiled 8002730, 210, 251, 0.02%, Pepper, nonbell, dried-Cooked; Fresh or N/S; CookMeth N/S95002350, 210, 7, 0.02%, Olive-Cooked; Fresh or N/S; Cook Meth N/S10002400, 110, 22, 0.02%, Orange-Uncooked; Fresh or N/S; Cook Meth N/S12000910, 120, 123, 0.02%, Cherry, juice-Uncooked; Frozen; Cook Meth N/S13010550, 120, 7, 0.02%, Blackberry-Uncooked; Frozen; Cook Meth N/S95003600, 240, 20, 0.02%, Strawberry, juice-Cooked; Canned; Cook Meth N/S25002900, 213, 255, 0.02%, Pork, meat-Cooked; Fresh or N/S; Fried 8002720, 230, 76, 0.02%, Pepper, nonbell-Cooked; Dried; Cook Meth N/S 8002730, 240, 198, 0.02%, Pepper, nonbell, dried-Cooked; Canned; Cook MethN/S95003590, 240, 22, 0.02%, Strawberry-Cooked; Canned; Cook Meth N/S 4012480, 110, 81, 0.02%, Parsley, leaves-Uncooked; Fresh or N/S; Cook MethN/S12000130, 130, 34, 0.02%, Apricot, dried-Uncooked; Dried; Cook Meth N/S25002930, 212, 214, 0.02%, Pork, fat-Cooked; Fresh or N/S; Boiled12000120, 110, 6, 0.02%, Apricot-Uncooked; Fresh or N/S; Cook Meth N/S 6010430, 222, 7, 0.01%, Bean, snap, succulent-Cooked; Frozen; Boiled 8002700, 221, 14, 0.01%, Pepper, bell-Cooked; Frozen; Baked15004020, 232, 170, 0.01%, Wheat, flour-Cooked; Dried; Boiled11000070, 211, 7, 0.01%, Apple, fruit with peel-Cooked; Fresh or N/S; Baked21000470, 211, 154, 0.01%, Beef, fat-Cooked; Fresh or N/S; Baked21000440, 212, 258, 0.01%, Beef, meat-Cooked; Fresh or N/S; Boiled 2001010, 110, 209, 0.01%, Chicory, tops-Uncooked; Fresh or N/S; Cook Meth N/S13010560, 110, 3, 0.01%, Blackberry, juice-Uncooked; Fresh or N/S; Cook MethN/S

435

8002720, 215, 161, 0.01%, Pepper, nonbell-Cooked; Fresh or N/S; Boiled/baked 8002730, 213, 166, 0.01%, Pepper, nonbell, dried-Cooked; Fresh or N/S; Fried 8002700, 212, 17, 0.01%, Pepper, bell-Cooked; Fresh or N/S; Boiled 8003790, 110, 67, 0.01%, Tomato, juice-Uncooked; Fresh or N/S; Cook Meth N/S21000470, 212, 187, 0.01%, Beef, fat-Cooked; Fresh or N/S; Boiled95001750, 240, 20, 0.01%, Grape-Cooked; Canned; Cook Meth N/S 8002700, 215, 32, 0.01%, Pepper, bell-Cooked; Fresh or N/S; Boiled/baked 8002340, 242, 19, 0.01%, Okra-Cooked; Canned; Boiled11000110, 212, 36, 0.01%, Apple, sauce-Cooked; Fresh or N/S; Boiled 8003790, 240, 91, 0.01%, Tomato, juice-Cooked; Canned; Cook Meth N/S15001210, 233, 172, 0.01%, Corn, field, meal-Cooked; Dried; Fried95003590, 211, 9, 0.01%, Strawberry-Cooked; Fresh or N/S; Baked95003600, 110, 6, 0.01%, Strawberry, juice-Uncooked; Fresh or N/S; Cook MethN/S15003250, 210, 69, 0.01%, Rice, flour-Cooked; Fresh or N/S; Cook Meth N/S27002220, 120, 173, 0.01%, Milk, fat-Uncooked; Frozen; Cook Meth N/S 9014000, 110, 38, 0.01%, Watermelon, juice-Uncooked; Fresh or N/S; Cook MethN/S15001240, 130, 125, 0.01%, Corn, field, syrup-Uncooked; Dried; Cook Meth N/S 6010430, 210, 4, 0.01%, Bean, snap, succulent-Cooked; Fresh or N/S; CookMeth N/S15004020, 210, 237, 0.01%, Wheat, flour-Cooked; Fresh or N/S; Cook Meth N/S15003250, 232, 39, 0.01%, Rice, flour-Cooked; Dried; Boiled12000900, 120, 9, 0.01%, Cherry-Uncooked; Frozen; Cook Meth N/S10002000, 232, 45, 0.01%, Lemon, juice-Cooked; Dried; Boiled95000190, 212, 15, 0.01%, Asparagus-Cooked; Fresh or N/S; Boiled 8002720, 232, 58, 0.01%, Pepper, nonbell-Cooked; Dried; Boiled 1010790, 110, 39, 0.01%, Carrot, juice-Uncooked; Fresh or N/S; Cook Meth N/S95001760, 240, 95, 0.01%, Grape, juice-Cooked; Canned; Cook Meth N/S13013210, 240, 19, 0.01%, Raspberry, juice-Cooked; Canned; Cook Meth N/S 1033000, 212, 51, 0.01%, Potato, tuber, w/o peel-Cooked; Fresh or N/S;Boiled95000730, 210, 22, 0.01%, Cactus-Cooked; Fresh or N/S; Cook Meth N/S 5010690, 110, 139, 0.01%, Cabbage-Uncooked; Fresh or N/S; Cook Meth N/S95003590, 120, 4, 0.01%, Strawberry-Uncooked; Frozen; Cook Meth N/S15001200, 230, 158, 0.01%, Corn, field, flour-Cooked; Dried; Cook Meth N/S 8001480, 214, 5, 0.01%, Eggplant-Cooked; Fresh or N/S; Fried/baked15001260, 230, 123, 0.01%, Corn, pop-Cooked; Dried; Cook Meth N/S15001200, 211, 105, 0.01%, Corn, field, flour-Cooked; Fresh or N/S; Baked 9021350, 240, 55, 0.01%, Cucumber-Cooked; Canned; Cook Meth N/S25002930, 240, 9, 0.01%, Pork, fat-Cooked; Canned; Cook Meth N/S15003250, 212, 19, 0.00%, Rice, flour-Cooked; Fresh or N/S; Boiled 9011870, 110, 8, 0.00%, Honeydew melon-Uncooked; Fresh or N/S; Cook MethN/S95002350, 212, 3, 0.00%, Olive-Cooked; Fresh or N/S; Boiled95001320, 240, 71, 0.00%, Cranberry, juice-Cooked; Canned; Cook Meth N/S15001200, 210, 106, 0.00%, Corn, field, flour-Cooked; Fresh or N/S; Cook MethN/S27002220, 211, 91, 0.00%, Milk, fat-Cooked; Fresh or N/S; Baked95002640, 210, 106, 0.00%, Peanut, butter-Cooked; Fresh or N/S; Cook Meth N/S12002850, 110, 9, 0.00%, Plum-Uncooked; Fresh or N/S; Cook Meth N/S 8003770, 212, 57, 0.00%, Tomato, puree-Cooked; Fresh or N/S; Boiled11000080, 110, 2, 0.00%, Apple, peeled fruit-Uncooked; Fresh or N/S; CookMeth N/S 8003770, 240, 48, 0.00%, Tomato, puree-Cooked; Canned; Cook Meth N/S 8003740, 210, 84, 0.00%, Tomatillo-Cooked; Fresh or N/S; Cook Meth N/S15001240, 120, 77, 0.00%, Corn, field, syrup-Uncooked; Frozen; Cook Meth N/S10002410, 240, 62, 0.00%, Orange, juice-Cooked; Canned; Cook Meth N/S27002220, 232, 39, 0.00%, Milk, fat-Cooked; Dried; Boiled13020570, 230, 3, 0.00%, Blueberry-Cooked; Dried; Cook Meth N/S 1031390, 213, 20, 0.00%, Dasheen, corm-Cooked; Fresh or N/S; Fried 8003760, 210, 22, 0.00%, Tomato, paste-Cooked; Fresh or N/S; Cook Meth N/S95001750, 210, 5, 0.00%, Grape-Cooked; Fresh or N/S; Cook Meth N/S12000140, 240, 5, 0.00%, Apricot, juice-Cooked; Canned; Cook Meth N/S15003240, 232, 60, 0.00%, Rice, brown-Cooked; Dried; Boiled

436

4012480, 212, 24, 0.00%, Parsley, leaves-Cooked; Fresh or N/S; Boiled25002900, 253, 59, 0.00%, Pork, meat-Cooked; Cured etc; Fried12000900, 240, 10, 0.00%, Cherry-Cooked; Canned; Cook Meth N/S15001200, 213, 58, 0.00%, Corn, field, flour-Cooked; Fresh or N/S; Fried13013210, 120, 11, 0.00%, Raspberry, juice-Uncooked; Frozen; Cook Meth N/S11000080, 221, 2, 0.00%, Apple, peeled fruit-Cooked; Frozen; Baked14000810, 211, 30, 0.00%, Cashew-Cooked; Fresh or N/S; Baked95002790, 240, 9, 0.00%, Pineapple-Cooked; Canned; Cook Meth N/S15004020, 231, 65, 0.00%, Wheat, flour-Cooked; Dried; Baked 6030420, 230, 79, 0.00%, Bean, pinto, seed-Cooked; Dried; Cook Meth N/S27002220, 210, 67, 0.00%, Milk, fat-Cooked; Fresh or N/S; Cook Meth N/S11002680, 240, 7, 0.00%, Pear, juice-Cooked; Canned; Cook Meth N/S95001790, 110, 30, 0.00%, Grape, wine and sherry-Uncooked; Fresh or N/S; CookMeth N/S 6030420, 232, 76, 0.00%, Bean, pinto, seed-Cooked; Dried; Boiled12000120, 213, 2, 0.00%, Apricot-Cooked; Fresh or N/S; Fried14002820, 211, 23, 0.00%, Pistachio-Cooked; Fresh or N/S; Baked 8003790, 210, 20, 0.00%, Tomato, juice-Cooked; Fresh or N/S; Cook Meth N/S 1010500, 250, 20, 0.00%, Beet, garden, roots-Cooked; Cured etc; Cook MethN/S95002630, 211, 30, 0.00%, Peanut-Cooked; Fresh or N/S; Baked 8003790, 212, 46, 0.00%, Tomato, juice-Cooked; Fresh or N/S; Boiled 6010430, 240, 1, 0.00%, Bean, snap, succulent-Cooked; Canned; Cook Meth N/S15004020, 212, 47, 0.00%, Wheat, flour-Cooked; Fresh or N/S; Boiled 4013550, 242, 1, 0.00%, Spinach-Cooked; Canned; Boiled 1032990, 212, 17, 0.00%, Potato, tuber, w/peel-Cooked; Fresh or N/S; Boiled 1031390, 212, 19, 0.00%, Dasheen, corm-Cooked; Fresh or N/S; Boiled15004010, 211, 26, 0.00%, Wheat, grain-Cooked; Fresh or N/S; Baked 8003750, 110, 41, 0.00%, Tomato-Uncooked; Fresh or N/S; Cook Meth N/S 1030820, 210, 19, 0.00%, Cassava-Cooked; Fresh or N/S; Cook Meth N/S19011440, 240, 39, 0.00%, Dillweed-Cooked; Canned; Cook Meth N/S11000100, 240, 16, 0.00%, Apple, juice-Cooked; Canned; Cook Meth N/S 1033660, 212, 33, 0.00%, Sweet potato-Cooked; Fresh or N/S; Boiled95002350, 221, 1, 0.00%, Olive-Cooked; Frozen; Baked95000230, 110, 52, 0.00%, Banana-Uncooked; Fresh or N/S; Cook Meth N/S15004010, 230, 42, 0.00%, Wheat, grain-Cooked; Dried; Cook Meth N/S 4012480, 210, 29, 0.00%, Parsley, leaves-Cooked; Fresh or N/S; Cook Meth N/S 9023080, 211, 28, 0.00%, Pumpkin-Cooked; Fresh or N/S; Baked 8002730, 232, 19, 0.00%, Pepper, nonbell, dried-Cooked; Dried; Boiled 6003490, 210, 32, 0.00%, Soybean, soy milk-Cooked; Fresh or N/S; Cook MethN/S95003600, 210, 1, 0.00%, Strawberry, juice-Cooked; Fresh or N/S; Cook MethN/S 9023090, 211, 19, 0.00%, Pumpkin, seed-Cooked; Fresh or N/S; Baked 4020860, 240, 42, 0.00%, Celery, juice-Cooked; Canned; Cook Meth N/S15001210, 230, 56, 0.00%, Corn, field, meal-Cooked; Dried; Cook Meth N/S15001200, 232, 19, 0.00%, Corn, field, flour-Cooked; Dried; Boiled 6030340, 232, 19, 0.00%, Bean, cowpea, seed-Cooked; Dried; Boiled26003390, 210, 22, 0.00%, Sheep, meat-Cooked; Fresh or N/S; Cook Meth N/S12000900, 210, 1, 0.00%, Cherry-Cooked; Fresh or N/S; Cook Meth N/S11000080, 213, 3, 0.00%, Apple, peeled fruit-Cooked; Fresh or N/S; Fried95001750, 120, 2, 0.00%, Grape-Uncooked; Frozen; Cook Meth N/S 6003480, 230, 20, 0.00%, Soybean, flour-Cooked; Dried; Cook Meth N/S11002680, 110, 9, 0.00%, Pear, juice-Uncooked; Fresh or N/S; Cook Meth N/S25002920, 210, 40, 0.00%, Pork, meat byproducts-Cooked; Fresh or N/S; CookMeth N/S25002930, 221, 19, 0.00%, Pork, fat-Cooked; Frozen; Baked95000190, 242, 10, 0.00%, Asparagus-Cooked; Canned; Boiled10001800, 110, 12, 0.00%, Grapefruit-Uncooked; Fresh or N/S; Cook Meth N/S 8003750, 211, 22, 0.00%, Tomato-Cooked; Fresh or N/S; Baked95002630, 112, 19, 0.00%, Peanut-Uncooked; Fresh or N/S; Boiled25002930, 242, 20, 0.00%, Pork, fat-Cooked; Canned; Boiled15001210, 232, 21, 0.00%, Corn, field, meal-Cooked; Dried; Boiled 8001480, 210, 5, 0.00%, Eggplant-Cooked; Fresh or N/S; Cook Meth N/S

437

15001210, 210, 19, 0.00%, Corn, field, meal-Cooked; Fresh or N/S; Cook MethN/S20003640, 211, 20, 0.00%, Sunflower, seed-Cooked; Fresh or N/S; Baked 8003760, 212, 26, 0.00%, Tomato, paste-Cooked; Fresh or N/S; Boiled25002900, 212, 24, 0.00%, Pork, meat-Cooked; Fresh or N/S; Boiled 6032030, 232, 22, 0.00%, Lentil, seed-Cooked; Dried; Boiled11002680, 120, 6, 0.00%, Pear, juice-Uncooked; Frozen; Cook Meth N/S11002660, 210, 3, 0.00%, Pear-Cooked; Fresh or N/S; Cook Meth N/S 1033660, 211, 10, 0.00%, Sweet potato-Cooked; Fresh or N/S; Baked10001060, 211, 5, 0.00%, Citrus citron-Cooked; Fresh or N/S; Baked15001210, 211, 27, 0.00%, Corn, field, meal-Cooked; Fresh or N/S; Baked 1013880, 212, 20, 0.00%, Turnip, roots-Cooked; Fresh or N/S; Boiled 8003770, 211, 21, 0.00%, Tomato, puree-Cooked; Fresh or N/S; Baked21000490, 210, 19, 0.00%, Beef, liver-Cooked; Fresh or N/S; Cook Meth N/S27002220, 215, 19, 0.00%, Milk, fat-Cooked; Fresh or N/S; Boiled/baked27002220, 230, 17, 0.00%, Milk, fat-Cooked; Dried; Cook Meth N/S 8002700, 222, 1, 0.00%, Pepper, bell-Cooked; Frozen; Boiled21000460, 210, 19, 0.00%, Beef, meat byproducts-Cooked; Fresh or N/S; CookMeth N/S21000440, 221, 21, 0.00%, Beef, meat-Cooked; Frozen; Baked25002900, 240, 4, 0.00%, Pork, meat-Cooked; Canned; Cook Meth N/S 8003750, 240, 16, 0.00%, Tomato-Cooked; Canned; Cook Meth N/S15004020, 213, 20, 0.00%, Wheat, flour-Cooked; Fresh or N/S; Fried27002220, 214, 19, 0.00%, Milk, fat-Cooked; Fresh or N/S; Fried/baked15001240, 230, 21, 0.00%, Corn, field, syrup-Cooked; Dried; Cook Meth N/S95002790, 110, 7, 0.00%, Pineapple-Uncooked; Fresh or N/S; Cook Meth N/S15004020, 215, 19, 0.00%, Wheat, flour-Cooked; Fresh or N/S; Boiled/baked26003410, 210, 21, 0.00%, Sheep, fat-Cooked; Fresh or N/S; Cook Meth N/S15004020, 221, 18, 0.00%, Wheat, flour-Cooked; Frozen; Baked 6030410, 232, 19, 0.00%, Bean, pink, seed-Cooked; Dried; Boiled 6030420, 210, 19, 0.00%, Bean, pinto, seed-Cooked; Fresh or N/S; Cook MethN/S15003240, 210, 3, 0.00%, Rice, brown-Cooked; Fresh or N/S; Cook Meth N/S 8003770, 221, 16, 0.00%, Tomato, puree-Cooked; Frozen; Baked15004020, 214, 20, 0.00%, Wheat, flour-Cooked; Fresh or N/S; Fried/baked13021370, 211, 2, 0.00%, Currant, dried-Cooked; Fresh or N/S; Baked 6010430, 221, 1, 0.00%, Bean, snap, succulent-Cooked; Frozen; Baked15001240, 210, 17, 0.00%, Corn, field, syrup-Cooked; Fresh or N/S; Cook MethN/S 8003760, 211, 18, 0.00%, Tomato, paste-Cooked; Fresh or N/S; Baked12002870, 130, 3, 0.00%, Plum, prune, dried-Uncooked; Dried; Cook Meth N/S 9021020, 210, 2, 0.00%, Chinese waxgourd-Cooked; Fresh or N/S; Cook MethN/S 8003750, 212, 13, 0.00%, Tomato-Cooked; Fresh or N/S; Boiled 1033000, 210, 5, 0.00%, Potato, tuber, w/o peel-Cooked; Fresh or N/S; CookMeth N/S 8002730, 221, 3, 0.00%, Pepper, nonbell, dried-Cooked; Frozen; Baked 1033000, 211, 9, 0.00%, Potato, tuber, w/o peel-Cooked; Fresh or N/S; Baked 8001480, 215, 2, 0.00%, Eggplant-Cooked; Fresh or N/S; Boiled/baked 1032990, 211, 6, 0.00%, Potato, tuber, w/peel-Cooked; Fresh or N/S; Baked 9021350, 150, 7, 0.00%, Cucumber-Uncooked; Cured etc; Cook Meth N/S21000470, 250, 8, 0.00%, Beef, fat-Cooked; Cured etc; Cook Meth N/S11000090, 210, 3, 0.00%, Apple, dried-Cooked; Fresh or N/S; Cook Meth N/S14002690, 211, 5, 0.00%, Pecan-Cooked; Fresh or N/S; Baked 2000510, 212, 1, 0.00%, Beet, garden, tops-Cooked; Fresh or N/S; Boiled 8003750, 215, 9, 0.00%, Tomato-Cooked; Fresh or N/S; Boiled/baked 9013990, 110, 4, 0.00%, Watermelon-Uncooked; Fresh or N/S; Cook Meth N/S 5010830, 212, 6, 0.00%, Cauliflower-Cooked; Fresh or N/S; Boiled95002810, 211, 6, 0.00%, Pineapple, juice-Cooked; Fresh or N/S; Baked95001320, 110, 3, 0.00%, Cranberry, juice-Uncooked; Fresh or N/S; Cook MethN/S12000140, 120, 1, 0.00%, Apricot, juice-Uncooked; Frozen; Cook Meth N/S14003910, 211, 2, 0.00%, Walnut-Cooked; Fresh or N/S; Baked20003640, 110, 2, 0.00%, Sunflower, seed-Uncooked; Fresh or N/S; Cook MethN/S

438

8002720, 242, 2, 0.00%, Pepper, nonbell-Cooked; Canned; Boiled 8001480, 213, 1, 0.00%, Eggplant-Cooked; Fresh or N/S; Fried27002220, 240, 5, 0.00%, Milk, fat-Cooked; Canned; Cook Meth N/S 8003750, 210, 7, 0.00%, Tomato-Cooked; Fresh or N/S; Cook Meth N/S11000100, 210, 4, 0.00%, Apple, juice-Cooked; Fresh or N/S; Cook Meth N/S21000440, 250, 5, 0.00%, Beef, meat-Cooked; Cured etc; Cook Meth N/S25002930, 222, 2, 0.00%, Pork, fat-Cooked; Frozen; Boiled 1013140, 110, 5, 0.00%, Radish, roots-Uncooked; Fresh or N/S; Cook Meth N/S11000110, 240, 3, 0.00%, Apple, sauce-Cooked; Canned; Cook Meth N/S27002220, 212, 5, 0.00%, Milk, fat-Cooked; Fresh or N/S; Boiled15001270, 212, 2, 0.00%, Corn, sweet-Cooked; Fresh or N/S; Boiled11000100, 120, 3, 0.00%, Apple, juice-Uncooked; Frozen; Cook Meth N/S 5010830, 222, 2, 0.00%, Cauliflower-Cooked; Frozen; Boiled 1034060, 210, 1, 0.00%, Yam, true-Cooked; Fresh or N/S; Cook Meth N/S25002930, 214, 2, 0.00%, Pork, fat-Cooked; Fresh or N/S; Fried/baked11000110, 211, 1, 0.00%, Apple, sauce-Cooked; Fresh or N/S; Baked 9023570, 215, 4, 0.00%, Squash, winter-Cooked; Fresh or N/S; Boiled/baked15001260, 231, 4, 0.00%, Corn, pop-Cooked; Dried; Baked21000460, 212, 2, 0.00%, Beef, meat byproducts-Cooked; Fresh or N/S; Boiled 1010500, 242, 2, 0.00%, Beet, garden, roots-Cooked; Canned; Boiled21000450, 230, 2, 0.00%, Beef, meat, dried-Cooked; Dried; Cook Meth N/S12002620, 211, 1, 0.00%, Peach, juice-Cooked; Fresh or N/S; Baked15003250, 120, 2, 0.00%, Rice, flour-Uncooked; Frozen; Cook Meth N/S12002860, 211, 2, 0.00%, Plum, prune, fresh-Cooked; Fresh or N/S; Baked10002420, 110, 1, 0.00%, Orange, peel-Uncooked; Fresh or N/S; Cook Meth N/S20003650, 900, 2, 0.00%, Sunflower, oil-Refined; FF N/A; Cook Meth N/S 9010750, 240, 1, 0.00%, Cantaloupe-Cooked; Canned; Cook Meth N/S 1033660, 210, 2, 0.00%, Sweet potato-Cooked; Fresh or N/S; Cook Meth N/S15001270, 222, 2, 0.00%, Corn, sweet-Cooked; Frozen; Boiled15001200, 231, 2, 0.00%, Corn, field, flour-Cooked; Dried; Baked95002630, 210, 2, 0.00%, Peanut-Cooked; Fresh or N/S; Cook Meth N/S 9023560, 212, 1, 0.00%, Squash, summer-Cooked; Fresh or N/S; Boiled 9023080, 212, 2, 0.00%, Pumpkin-Cooked; Fresh or N/S; Boiled25002900, 251, 2, 0.00%, Pork, meat-Cooked; Cured etc; Baked 4012480, 213, 1, 0.00%, Parsley, leaves-Cooked; Fresh or N/S; Fried15001240, 211, 2, 0.00%, Corn, field, syrup-Cooked; Fresh or N/S; Baked25002900, 232, 1, 0.00%, Pork, meat-Cooked; Dried; Boiled95001760, 210, 1, 0.00%, Grape, juice-Cooked; Fresh or N/S; Cook Meth N/S20003640, 210, 1, 0.00%, Sunflower, seed-Cooked; Fresh or N/S; Cook Meth N/S 6003490, 211, 1, 0.00%, Soybean, soy milk-Cooked; Fresh or N/S; Baked95002790, 210, 1, 0.00%, Pineapple-Cooked; Fresh or N/S; Cook Meth N/S95003600, 120, 1, 0.00%, Strawberry, juice-Uncooked; Frozen; Cook Meth N/S95001760, 120, 1, 0.00%, Grape, juice-Uncooked; Frozen; Cook Meth N/S21000440, 214, 1, 0.00%, Beef, meat-Cooked; Fresh or N/S; Fried/baked15001260, 210, 1, 0.00%, Corn, pop-Cooked; Fresh or N/S; Cook Meth N/S 8003770, 242, 1, 0.00%, Tomato, puree-Cooked; Canned; Boiled 8001480, 212, 1, 0.00%, Eggplant-Cooked; Fresh or N/S; Boiled21000490, 213, 1, 0.00%, Beef, liver-Cooked; Fresh or N/S; Fried 1010500, 212, 1, 0.00%, Beet, garden, roots-Cooked; Fresh or N/S; Boiled19012490, 221, 1, 0.00%, Parsley, dried leaves-Cooked; Frozen; Baked21000470, 221, 1, 0.00%, Beef, fat-Cooked; Frozen; Baked 8002700, 232, 1, 0.00%, Pepper, bell-Cooked; Dried; Boiled 6032560, 212, 1, 0.00%, Pea, dry-Cooked; Fresh or N/S; Boiled 5010830, 110, 1, 0.00%, Cauliflower-Uncooked; Fresh or N/S; Cook Meth N/S 8003770, 215, 1, 0.00%, Tomato, puree-Cooked; Fresh or N/S; Boiled/baked15004040, 230, 1, 0.00%, Wheat, bran-Cooked; Dried; Cook Meth N/S10002010, 230, 1, 0.00%, Lemon, peel-Cooked; Dried; Cook Meth N/S 6030380, 232, 1, 0.00%, Bean, lima, seed-Cooked; Dried; Boiled12000140, 110, 1, 0.00%, Apricot, juice-Uncooked; Fresh or N/S; Cook MethN/S 4012040, 110, 1, 0.00%, Lettuce, head-Uncooked; Fresh or N/S; Cook Meth N/S15001230, 210, 1, 0.00%, Corn, field, starch-Cooked; Fresh or N/S; Cook MethN/S

439

Appendix VI. Residue Data Files (RDFs) for the Acute Monte Carlo Analysis

Crop groups 1A and 1AB - Root vegetables

RDF1CARROT - CA-ONLY PDP 2006 2007PCT=6%TOTALZ=317TOTALLOD=20 LODRES=0.001

Crop group 1CD - Tuber and corm vegetables

RDF2POTATO - CA-ONLY PDP 2000 2001 2002PCT=3%TOTALZ=318TOTALLOD=10 LODRES=0.004

RDF3POTATO FROZEN - CA-ONLY PDP 2006 2007PCT=3%TOTALZ=337TOTALLOD=10 LODRES=0.001

RDF4SWEET POTATO - CA-ONLY PDP 2003 2004PCT=38%TOTALZ=207TOTALLOD=126 LODRES=0.0040.013

Crop group 2 - Leaves of root and tuber vegetables

(No RDFs for crop group 2.)

Crop group 4A - Leafy greens

RDF5LETTUCE - CA-ONLY PDP 2004 2005PCT=4%TOTALZ=323TOTALLOD=13 LODRES=0.001

RDF6SPINACH - CA-ONLY PDP 2006PCT=2%TOTALZ=111TOTALLOD=2 LODRES=0.001

440

RDF7CANNED SPINACH - CA-ONLY PDP 2004PCT=2%TOTALZ=82TOTALLOD=2 LODRES=0.042

Crop group 4B - Leafy petioles

RDF8CELERY - CA-ONLY PDP 2007PCT=4%TOTALZ=160TOTALLOD=7 LODRES=0.001

Crop group 5A - Brassica: head and stem

RDF9BROCCOLI - CA-ONLY PDP 2006 2007PCT=9%TOTALZ=191TOTALLOD=12 LODRES=0.0005

Crop group 5B - Brassica: leafy greens

RDF10COLLARD - CA-ONLY PDP 2006 2007PCT=11%TOTALZ=87TOTALLOD=11 LODRES=0.001

RDF11KALE - CA-ONLY PDP 2006 2007PCT=2%TOTALZ=108TOTALLOD=2 LODRES=0.001

RDF80TURNIP GREENS - COLLARD DATAPCT=100%TOTALZ=0TOTALLOD=110 LODRES=0.001

Crop group 6 - Soybean

RDF12SOYBEAN - not CA-ONLY PDP 2004 2005PCT=100% (BLENDED)TOTALZ=0TOTALLOD=1254 LODRES=0.015

Crop group 6A - Edible-pod legume vegetables

441

RDF71GREEN BEANS - CA-ONLY 2005 2007PCT=14%TOTALZ=179TOTALLOD=28 LODRES=0.0010.19

RDF72GREEN BEANS, CANNED - CA-ONLY 2004PCT=14%TOTALZ=26TOTALLOD=6 LODRES=0.001

RDF73GREEN BEANS, FROZEN - CA-ONLY 2005PCT=14%TOTALZ=107TOTALLOD=15 LODRES=0.0010.0080.0030.003

RDF74SWEET PEAS - CA-ONLY 2001 2002 (c/f) 2003 (f) 2006 (f)**PCT=1%TOTALZ=343TOTALLOD=3 LODRES=0.004

Crop group 6C - Dried shelled peas / beans (except soybeans)

(No RDFs for crop group 6C.)

Crop group 8 - Fruiting vegetables

RDF13EGGPLANT - CA-ONLY 2005 2006PCT=13%TOTALZ=291TOTALLOD=32 LODRES=0.0050.180.130.120.1

0.10.0880.048

0.0430.0170.017

0.0170.017

RDF14SWEET BELL PEPPER - CA-ONLY 2002 2003 2004PCT=12%TOTALZ=296TOTALLOD=0 LODRES=0.00050.810.720.65

0.520.50.47

0.390.390.37

0.310.290.27

442

0.260.260.260.250.230.170.170.14

0.130.120.10.0930.0890.080.075

0.0620.0530.0490.040.0370.0340.03

0.00330.00270.00260.0020.0020.002

RDF15TOMATO - CA-ONLY PDP 2007PCT=9%TOTALZ=151TOTALLOD=15 LODRES=0.003

RDF16TOMATO PASTE - CA-ONLY PDP 2001PCT=100% (BLENDED)TOTALZ=0TOTALLOD=83 LODRES=0.0055

Crop group 9A - Curcurbits: melons

RDF17CANTALOUPE - CA-ONLY PDP 2004 2005PCT=13%TOTALZ=256TOTALLOD=18 LODRES=0.0010.110.0250.0240.0220.0120.012

0.0110.010.0090.0090.008

0.00740.0030.0030.0030.003

0.0030.0030.0030.003

RDF18WATERMELON - CA-ONLY PDP 2005 2006PCT=12%TOTALZ=148TOTALLOD=20 LODRES=0.001

RDF78HONEYDEW (CANTALOUPE DATA - CA-ONLY PDP 2004 2005)PCT=100%TOTALZ=0TOTALLOD=274 LODRES=0.0010.110.0250.0240.0220.0120.012

0.0110.010.0090.0090.008

0.00740.0030.0030.0030.003

0.0030.0030.0030.003

443

Crop group 9B - Curcurbits: squash / cucumbers

RDF19CUCUMBER - CA-ONLY PDP 2002 2003 2004PCT=22%TOTALZ=261TOTALLOD=60 LODRES=0.0040.0590.0460.0440.043

0.0420.0370.0350.022

0.0130.0130.0130.013

0.0030.003

RDF29SUMMER SQUASH - CA-ONLY PDP 2006 2007PCT=24%TOTALZ=160TOTALLOD=49 LODRES=0.0010.003

RDF30WINTER SQUASH - CA-ONLY PDP 2004 2005 2006PCT=24%TOTALZ=255TOTALLOD=80 LODRES=0.001

Crop group 10 - Citrus fruits

RDF31GRAPEFRUIT - CA-ONLY PDP 2005 2006PCT=11%TOTALZ=298TOTALLOD=34 LODRES=0.0010.0030.0030.003

RDF32ORANGE - CA-ONLY PDP 2004 2005PCT=4%TOTALZ=323TOTALLOD=2 LODRES=0.0010.0590.0570.035

0.0150.0070.003

0.0030.0030.003

0.0030.003

444

RDF33ORANGE JUICE - CA-ONLY PDP 2004 2005 2006PCT=100% (BLENDED)TOTALZ=0TOTALLOD=262 LODRES=0.0010.0160.010.0090.0090.0090.00890.00780.0030.0030.0030.0030.0030.0030.0030.0030.0030.0030.0030.003

0.0030.0030.0030.0030.0030.0030.0030.0030.0030.0030.0030.0030.0030.0030.0030.0030.0030.0030.003

0.0030.0030.0030.0030.0030.0030.0030.0030.0030.0030.0030.0030.0030.0030.0030.0030.0030.003

0.0030.0030.0030.0030.0030.0030.0030.0030.0030.0030.0030.0030.0030.0030.0030.0030.003

Crop group 11 - Pome fruits

RDF34APPLE - CA-ONLY 2004 2005PCT=35%TOTALZ=218TOTALLOD=102 LODRES=0.0010.490.450.180.160.16

0.0750.0410.0170.016

0.0150.0110.0030.003

0.0030.0030.003

RDF35APPLE JUICE - CA-ONLY 2007PCT=100% (BLENDED)TOTALZ=0TOTALLOD=71 LODRES=0.0010.0310.0240.00780.003

0.0030.0030.003

0.0030.0030.003

0.0030.003

445

RDF36APPLE SAUCE - CA-ONLY 2006PCT=100% (BLENDED)TOTALZ=0TOTALLOD=141 LODRES=0.0010.0470.0410.040.0380.0340.0320.03

0.030.0290.0250.0180.0170.0160.015

0.0110.00960.00960.00860.0030.0030.003

0.0030.0030.0030.0030.0030.003

RDF37PEAR - CA-ONLY PDP 2004 2005PCT=5%TOTALZ=279TOTALLOD=3 LODRES=0.0020.320.270.20.12

0.0640.0530.023

0.0220.0030.003

0.0030.003

Crop group 12 - Stone fruits

RDF38CHERRY - CA-ONLY PDP 2007PCT=33%TOTALZ=68TOTALLOD=19 LODRES=0.0010.840.740.330.22

0.120.080.0670.067

0.0510.0360.0280.013

0.010.0030.003

RDF39NECTARINE - CA-ONLY PDP 2007PCT=13%TOTALZ=107TOTALLOD=12 LODRES=0.0030.810.0660.0450.039

RDF40PEACH - CA-ONLY PDP 2006 2007PCT=13%TOTALZ=117TOTALLOD=7 LODRES=0.0010.50.180.11

0.0860.0840.062

0.0310.0190.0079

0.0030.003

446

RDF41PLUM - CA-ONLY PDP 2005 2006PCT=8%TOTALZ=211TOTALLOD=1 LODRES=0.050.0680.0320.0170.0170.017

0.0170.0170.0170.0170.017

0.0170.0170.0170.017

0.0170.0170.017

RDF42DRIED PLUM - CA-ONLY PDP 2005 2006PCT=8%TOTALZ=94TOTALLOD=8 LODRES=0.05

RDF77APRICOT (NECTARINE DATA - CA-ONLY PDP 2007)PCT=100%TOTALZ=0TOTALLOD=129 LODRES=0.0030.810.0660.0450.039

Crop group 13A - Caneberry group

RDF43RASPBERRY - FDA DATA**PCT=7%TOTALZ=196TOTALLOD=0 LODRES=0.0013.791.521.180.0190.040.4362.780.2983.430.0320.0280.0050.016

1.130.0210.190.020.0050.0050.0050.0050.0050.0050.0050.0050.03

0.130.0050.0450.160.130.080.0050.0341.070.0070.0630.160.88

0.0050.0260.0050.350.060.830.0050.063.20.230.0050.12

**The number of detects for raspberries (51) was higher than the theoretical maximum (17, or 247 x 7%) when pct is taken intoaccount. Consequently, there were no samples set at the LOD; all non-detects were considered to be at zero.

447

RDF79BLACKBERRY (RASPBERRY - FDA DATA)PCT=100%TOTALZ=0TOTALLOD=196 LODRES=0.0013.791.521.180.0190.040.4362.780.2983.430.0320.0280.0050.016

1.130.0210.190.020.0050.0050.0050.0050.0050.0050.0050.0050.03

0.130.0050.0450.160.130.080.0050.0341.070.0070.0630.160.88

0.0050.0260.0050.350.060.830.0050.063.20.230.0050.12

Crop group 13B - Bushberry group

RDF44BLUEBERRY - FDA DATAPCT=44%TOTALZ=119TOTALLOD=70 LODRES=0.0010.3420.2451.060.1460.1120.206

0.2340.0050.194.380.1190.005

0.0050.520.232.050.089.7

0.0050.020.0540.150.012

Crop group 14 - Tree nuts

RDF45ALMOND - CA-ONLY PDP 2007PCT=1%TOTALZ=82TOTALLOD=1 LODRES=0.0075

Crop group 15 - Cereal grains

RDF48SWEET CORN - CA-ONLY PDP 2001 2002 2003PCT=1%TOTALZ=324TOTALLOD=1 LODRES=0.004

RDF49CORN SYRUP - not CA-ONLY PDP 1998 1999PCT=100%TOTALZ=0TOTALLOD=438 LODRES=0.003

448

RDF50RICE - CA-ONLY PDP 2000 2001 2002PCT=100%TOTALZ=0TOTALLOD=214 LODRES=0.0030.0380.0380.0260.0230.010

RDF51WHEAT - CA-ONLY PDP 2005 2006PCT=100%TOTALZ=0TOTALLOD=1268 LODRES=0.003

RDF52WHEAT FLOUR - CA-ONLY PDP 2003 2004PCT=100%TOTALZ=0TOTALLOD=299 LODRES=0.003

Crop group 19A - Herbs

(No RDFs for crop group 19A.)

Crop group O - Other

RDF53ASPARAGUS - CA-ONLY 2002 2003PCT=45%TOTALZ=136TOTALLOD=112 LODRES=0.0040.160.013

RDF54CANNED ASPARAGUS - CA-ONLY 2003PCT=45% (ASPARAGUS DATA)TOTALZ=46TOTALLOD=38 LODRES=0.004

RDF55BANANA - CA-ONLY 2006 2007PCT=100% (IMPORTED)TOTALZ=0TOTALLOD=334 LODRES=0.0010.0030.003

449

RDF56CRANBERRY - CA-ONLY 2006PCT=68%TOTALZ=14TOTALLOD=12 LODRES=0.0010.0030.0030.0030.003

RDF57GRAPE - CA-ONLY 2004 2005PCT=10%TOTALZ=302TOTALLOD=15 LODRES=0.0010.510.470.440.360.36

0.230.10.0660.0540.046

0.0350.0260.0260.0140.0084

0.0030.0030.0030.003

RDF58GRAPE JUICE - CA-ONLY 1998 1999PCT=100%TOTALZ=0TOTALLOD=253 LODRES=0.0040.0550.0440.0390.028

0.0130.0130.013

0.0130.0130.013

0.0130.013

RDF59RAISIN - CA-ONLY 2006 2007PCT=10%TOTALZ=156TOTALLOD=15 LODRES=0.0010.0080.003

RDF76OLIVE**PCT=2%TOTALZ=588TOTALLOD=0 LODRES=0.02

**The RDF for olives was based on a field trial in which 12/12 samples were detects. To calculate a sample size in which 98% ofthe samples were zero (i.e., 2% pct), the following calculation was carried out: (12 / 0.02) - 12 = 588.

RDF60PEANUT BUTTER AND PEANUT - CA-ONLY PDP 2007PCT=100% (BLENDED)TOTALZ=0TOTALLOD=166 LODRES=0.005

450

RDF61PINEAPPLE - CA-ONLY 2000 2001 2002PCT=100% (IMPORT)TOTALZ=0TOTALLOD=320 LODRES=0.0040.110.110.043

0.0130.0130.013

0.0130.013

0.013

RDF62STRAWBERRY - CA-ONLY 2004 2005PCT=27%TOTALZ=245TOTALLOD=38 LODRES=0.0010.430.20.0670.059

0.0450.0390.0350.003

0.0030.0030.0030.003

0.0030.003

RDF63WATER, DRINKING - CA-ONLY 2005 2006, 2007 not CA-ONLYPCT=100% (BLENDED)TOTALZ=0TOTALLOD=404 LODRES=0.000012

451

RDF64WATER, BOTTLED - CA-ONLY 2005 2006PCT=100% (BLENDED)TOTALZ=0TOTALLOD=140 LODRES=0.000004

Crop group M - Meat

(Note: No RDFs for crop group M.)

Crop group D - Dairy products

RDF70MILK - CA-ONLY 2004 2005PCT=100%TOTALZ=0TOTALLOD=335 LODRES=0.000060.000083

RFD75HEAVY CREAM - CA-ONLY 2005 2007PCT=100%TOTALZ=0TOTALLOD=250 LODRES=0.013

452

Appendix VII. DEEM-FCID® Chronic and Oncogenic Dietary Exposure Assessment andRisk Calculations

VII-1. Chronic Residue Levels

Filename: H:\ARubin\Corel\CARBARYL\NEW DIETARY August 2009\DEEM files\cbl chronic.R98Chemical: carbarylRfD(Chronic): 0 mg/kg bw/day NOEL(Chronic): 0 mg/kg bw/dayRfD(Acute): 0 mg/kg bw/day NOEL(Acute): 0 mg/kg bw/dayDate created/last modified: 12-10-2009/10:32:53/14 Program ver. 2.03--------------------------------------------------------------------------------

EPA Crop Commodity Name Def Res Adj.Factors RDL Comment Code Grp (ppm) #1 #2 Pntr-------- ---- ------------------------------- ---------- ------ ------ --- -------01010500 1AB Beet, garden, roots 0.006000 1.000 1.000 -01010501 1AB Beet, garden, roots-babyfood 0.006000 1.000 1.000 -01010520 1A Beet, sugar 0.006000 1.000 0.040 -01010521 1A Beet, sugar-babyfood 0.006000 1.000 0.040 -01010530 1A Beet, sugar, molasses 0.006000 1.000 0.040 -01010531 1A Beet, sugar, molasses-babyfood 0.006000 1.000 0.040 -01010670 1AB Burdock 0.006000 1.000 1.000 -01010780 1AB Carrot 0.001000 1.000 1.000 1 -01010781 1AB Carrot-babyfood 0.001000 1.000 1.000 1 -01010790 1AB Carrot, juice 0.006000 1.000 1.000 -01010840 1AB Celeriac 0.006000 1.000 1.000 -01011000 1AB Chicory, roots 0.006000 1.000 1.000 -01011680 1AB Ginseng, dried 0.006000 1.000 1.000 -01011900 1AB Horseradish 0.006000 1.000 1.000 -01012500 1AB Parsley, turnip rooted 0.006000 1.000 1.000 -01012510 1AB Parsnip 0.006000 1.000 1.000 -01012511 1AB Parsnip-babyfood 0.006000 1.000 1.000 -01013140 1AB Radish, roots 0.006000 1.000 1.000 -01013160 1AB Radish, Oriental, roots 0.006000 1.000 1.000 -01013270 1AB Rutabaga 0.006000 1.000 1.000 -01013310 1AB Salsify, roots 0.006000 1.000 1.000 -01013880 1AB Turnip, roots 0.006000 1.000 1.000 -01030150 1CD Arrowroot, flour 0.013000 1.000 1.000 -01030151 1CD Arrowroot, flour-babyfood 0.013000 1.000 1.000 -01030170 1CD Artichoke, Jerusalem 0.013000 1.000 1.000 -01030820 1CD Cassava 0.013000 1.000 1.000 -01030821 1CD Cassava-babyfood 0.013000 1.000 1.000 -01031390 1CD Dasheen, corm 0.013000 1.000 1.000 -01031660 1CD Ginger 0.013000 1.000 1.000 -01031661 1CD Ginger-babyfood 0.013000 1.000 1.000 -01031670 1CD Ginger, dried 0.013000 1.000 1.000 -01032960 1C Potato, chips 0.008000 1.000 0.040 2 -01032970 1C Potato, dry (granules/ flakes) 0.008000 1.000 0.400 2 -01032971 1C Potato, dry (granules/ flakes)-b 0.008000 1.000 0.400 2 -01032980 1C Potato, flour 0.008000 1.000 6.500 2 -01032981 1C Potato, flour-babyfood 0.008000 1.000 6.500 2 -01032990 1C Potato, tuber, w/peel 210-Cooked; Fresh or N/S; Cook Meth N/S 0.004000 1.000 1.000 2 - 211-Cooked; Fresh or N/S; Baked 0.004000 1.000 1.200 2 - 212-Cooked; Fresh or N/S; Boiled 0.004000 1.000 2.500 2 - 213-Cooked; Fresh or N/S; Fried 0.004000 1.000 0.040 2 -01032991 1C Potato, tuber, w/peel-babyfood 0.004000 1.000 1.000 2 -01033000 1C Potato, tuber, w/o peel 110-Uncooked; Fresh or N/S; Cook Meth N/S

453

0.004000 1.000 1.000 2 - 210-Cooked; Fresh or N/S; Cook Meth N/S 0.004000 1.000 1.000 2 - 211-Cooked; Fresh or N/S; Baked 0.004000 1.000 1.200 2 - 212-Cooked; Fresh or N/S; Boiled 0.004000 1.000 2.500 2 - 213-Cooked; Fresh or N/S; Fried 0.004000 1.000 0.040 2 - 221-Cooked; Frozen; Baked 0.001000 1.000 1.000 2 - 223-Cooked; Frozen; Fried 0.001000 1.000 0.040 2 - 232-Cooked; Dried; Boiled 0.004000 1.000 2.500 2 - 233-Cooked; Dried; Fried 0.004000 1.000 0.040 2 - 240-Cooked; Canned; Cook Meth N/S 0.004000 1.000 1.000 2 - 242-Cooked; Canned; Boiled 0.004000 1.000 2.500 2 - 252-Cooked; Cured etc; Boiled 0.004000 1.000 2.500 2 - 253-Cooked; Cured etc; Fried 0.004000 1.000 0.040 2 -01033001 1C Potato, tuber, w/o peel-babyfood 0.004000 1.000 1.000 2 -01033660 1CD Sweet potato 0.002522 1.000 1.000 4 -01033661 1CD Sweet potato-babyfood 0.002522 1.000 1.000 4 -01033710 1CD Tanier, corm 0.013000 1.000 1.000 -01033870 1CD Turmeric 0.013000 1.000 1.000 -01034060 1CD Yam, true 0.013000 1.000 1.000 -01034070 1CD Yam bean 0.013000 1.000 1.000 -02000510 2 Beet, garden, tops 0.093000 1.000 1.000 -02001010 2 Chicory, tops 0.093000 1.000 1.000 -02001400 2 Dasheen, leaves 0.093000 1.000 1.000 -02003150 2 Radish, tops 0.093000 1.000 1.000 -02003170 2 Radish, Oriental, tops 0.093000 1.000 1.000 -02003320 2 Salsify, tops 0.093000 1.000 1.000 -04011380 4A Dandelion, leaves 0.093000 1.000 1.000 -04011500 4A Endive 0.093000 1.000 1.000 -04012040 4A Lettuce, head 0.001012 1.000 1.000 5 -04012050 4A Lettuce, leaf 0.001012 1.000 1.000 5 -04012480 4A Parsley, leaves 0.093000 1.000 1.000 -04013550 4A Spinach 110-Uncooked; Fresh or N/S; Cook Meth N/S 0.001000 1.000 1.000 6 - 210-Cooked; Fresh or N/S; Cook Meth N/S 0.001000 1.000 1.000 6 - 211-Cooked; Fresh or N/S; Baked 0.001000 1.000 1.000 6 - 212-Cooked; Fresh or N/S; Boiled 0.001000 1.000 1.000 6 - 213-Cooked; Fresh or N/S; Fried 0.001000 1.000 1.000 6 - 215-Cooked; Fresh or N/S; Boiled/baked 0.001000 1.000 1.000 6 - 220-Cooked; Frozen; Cook Meth N/S 0.001000 1.000 1.000 6 - 221-Cooked; Frozen; Baked 0.001000 1.000 1.000 6 - 222-Cooked; Frozen; Boiled 0.001000 1.000 1.000 6 - 232-Cooked; Dried; Boiled 0.001000 1.000 1.000 6 - 240-Cooked; Canned; Cook Meth N/S 0.004200 1.000 1.000 6 - 242-Cooked; Canned; Boiled 0.004200 1.000 1.000 6 -04013551 4A Spinach-babyfood 240-Cooked; Canned; Cook Meth N/S 0.004200 1.000 1.000 6 -04020760 4B Cardoon 3.000000 1.000 1.000 -04020850 4B Celery 0.001000 1.000 1.000 8 -04020851 4B Celery-babyfood 0.001000 1.000 1.000 8 -04020860 4B Celery, juice 3.000000 1.000 1.000 -04020870 4B Celtuce 3.000000 1.000 1.000 -

454

04021520 4B Fennel, Florence 3.000000 1.000 1.000 -04023220 4B Rhubarb 3.000000 1.000 1.000 -04023670 4B Swiss chard 3.000000 1.000 1.000 -05010610 5A Broccoli 0.000500 1.000 1.000 9 -05010611 5A Broccoli-babyfood 0.000500 1.000 1.000 9 -05010620 5A Broccoli, Chinese 0.003000 1.000 1.000 -05010640 5A Brussels sprouts 110-Uncooked; Fresh or N/S; Cook Meth N/S 0.003000 1.000 1.000 - 212-Cooked; Fresh or N/S; Boiled 0.003000 1.000 0.100 - 222-Cooked; Frozen; Boiled 0.003000 1.000 0.100 -05010690 5A Cabbage 110-Uncooked; Fresh or N/S; Cook Meth N/S 0.003000 1.000 1.000 - 150-Uncooked; Cured etc; Cook Meth N/S 0.003000 1.000 1.000 - 210-Cooked; Fresh or N/S; Cook Meth N/S 0.003000 1.000 0.100 - 211-Cooked; Fresh or N/S; Baked 0.003000 1.000 0.100 - 212-Cooked; Fresh or N/S; Boiled 0.003000 1.000 0.100 - 213-Cooked; Fresh or N/S; Fried 0.003000 1.000 0.100 - 221-Cooked; Frozen; Baked 0.003000 1.000 0.100 - 230-Cooked; Dried; Cook Meth N/S 0.003000 1.000 0.100 - 232-Cooked; Dried; Boiled 0.003000 1.000 0.100 - 240-Cooked; Canned; Cook Meth N/S 0.003000 1.000 0.100 - 242-Cooked; Canned; Boiled 0.003000 1.000 0.100 - 245-Cooked; Canned; Boiled/baked 0.003000 1.000 0.100 - 250-Cooked; Cured etc; Cook Meth N/S 0.003000 1.000 0.100 - 255-Cooked; Cured etc; Boiled/baked 0.003000 1.000 0.100 -05010710 5A Cabbage, Chinese, napa 0.003000 1.000 1.000 -05010720 5A Cabbage, Chinese, mustard 0.003000 1.000 1.000 -05010830 5A Cauliflower 0.003000 1.000 1.000 -05011960 5A Kohlrabi 0.003000 1.000 1.000 -05020630 5B Broccoli raab 1.700000 1.000 1.000 -05020700 5B Cabbage, Chinese, bok choy 1.700000 1.000 1.000 -05021170 5B Collards 0.001000 1.000 1.000 10 -05021940 5B Kale 0.001000 1.000 1.000 11 -05022290 5B Mustard greens 1.700000 1.000 1.000 -05023180 5B Rape greens 1.700000 1.000 1.000 -05023890 5B Turnip, greens 1.700000 1.000 1.000 -06003470 6 Soybean, seed 0.001500 1.000 1.000 12 -06003480 6 Soybean, flour 0.003000 1.000 1.000 -06003481 6 Soybean, flour-babyfood 0.003000 1.000 1.000 -06003490 6 Soybean, soy milk 0.003000 1.000 1.000 -06003491 6 Soybean, soy milk-babyfood or in 0.003000 1.000 1.000 -06003500 6 Soybean, oil 0.003000 1.000 0.005 -06003501 6 Soybean, oil-babyfood 0.003000 1.000 0.005 -06010430 6A Bean, snap, succulent 0.001909 1.000 1.000 71 -06010431 6A Bean, snap, succulent-babyfood 0.001909 1.000 1.000 71 -06012570 6A Pea, edible podded, succulent 110-Uncooked; Fresh or N/S; Cook Meth N/S 0.002843 1.000 0.150 74 - 210-Cooked; Fresh or N/S; Cook Meth N/S 0.002843 1.000 0.150 74 - 212-Cooked; Fresh or N/S; Boiled 0.002843 1.000 0.150 74 -

455

213-Cooked; Fresh or N/S; Fried 0.002843 1.000 0.150 74 - 220-Cooked; Frozen; Cook Meth N/S 0.002843 1.000 0.150 74 - 221-Cooked; Frozen; Baked 0.002843 1.000 0.150 74 -06030300 6C Bean, black, seed 0.003000 1.000 1.000 -06030320 6C Bean, broad, seed 0.003000 1.000 1.000 -06030340 6C Bean, cowpea, seed 0.003000 1.000 1.000 -06030350 6C Bean, great northern, seed 0.003000 1.000 1.000 -06030360 6C Bean, kidney, seed 0.003000 1.000 1.000 -06030380 6C Bean, lima, seed 0.003000 1.000 1.000 -06030390 6C Bean, mung, seed 0.003000 1.000 1.000 -06030400 6C Bean, navy, seed 0.003000 1.000 1.000 -06030410 6C Bean, pink, seed 0.003000 1.000 1.000 -06030420 6C Bean, pinto, seed 0.003000 1.000 1.000 -06030980 6C Chickpea, seed 0.003000 1.000 1.000 -06030981 6C Chickpea, seed-babyfood 0.003000 1.000 1.000 -06030990 6C Chickpea, flour 0.003000 1.000 1.000 -06031820 6C Guar, seed 0.003000 1.000 1.000 -06031821 6C Guar, seed-babyfood 0.003000 1.000 1.000 -06032030 6C Lentil, seed 0.003000 1.000 1.000 -06032560 6C Pea, dry 0.003000 1.000 1.000 -06032561 6C Pea, dry-babyfood 0.003000 1.000 1.000 -06032580 6C Pea, pigeon, seed 0.003000 1.000 1.000 -08001480 8 Eggplant 0.007439 1.000 1.000 13 -08002340 8 Okra 150-Uncooked; Cured etc; Cook Meth N/S 0.810000 1.000 1.000 - 210-Cooked; Fresh or N/S; Cook Meth N/S 0.810000 1.000 0.610 - 212-Cooked; Fresh or N/S; Boiled 0.810000 1.000 0.180 - 213-Cooked; Fresh or N/S; Fried 0.810000 1.000 0.610 - 220-Cooked; Frozen; Cook Meth N/S 0.810000 1.000 0.610 - 222-Cooked; Frozen; Boiled 0.810000 1.000 0.180 - 240-Cooked; Canned; Cook Meth N/S 0.810000 1.000 0.610 - 242-Cooked; Canned; Boiled 0.810000 1.000 0.180 -08002700 8 Pepper, bell 0.025591 1.000 1.000 14 -08002701 8 Pepper, bell-babyfood 0.025591 1.000 1.000 14 -08002710 8 Pepper, bell, dried 0.810000 1.000 1.000 14 -08002711 8 Pepper, bell, dried-babyfood 0.810000 1.000 1.000 14 -08002720 8 Pepper, nonbell 0.810000 1.000 1.000 -08002721 8 Pepper, nonbell-babyfood 0.810000 1.000 1.000 -08002730 8 Pepper, nonbell, dried 0.810000 1.000 1.000 -08003740 8 Tomatillo 0.006000 1.000 1.000 -08003750 8 Tomato 0.003000 1.000 1.000 15 -08003751 8 Tomato-babyfood 0.003000 1.000 1.000 15 -08003760 8 Tomato, paste 0.005500 1.000 0.650 16 -08003761 8 Tomato, paste-babyfood 0.005500 1.000 0.650 16 -08003770 8 Tomato, puree 0.011000 1.000 0.650 16 -08003771 8 Tomato, puree-babyfood 0.011000 1.000 0.650 16 -08003780 8 Tomato, dried 0.006000 1.000 0.520 -08003781 8 Tomato, dried-babyfood 0.006000 1.000 0.520 -08003790 8 Tomato, juice 0.011000 1.000 0.520 -09010750 9A Cantaloupe 0.001896 1.000 1.000 17 -09010800 9A Casaba 0.610000 1.000 1.000 -09011870 9A Honeydew melon 0.610000 1.000 1.000 78 -09013990 9A Watermelon 0.001000 1.000 1.000 18 -09014000 9A Watermelon, juice 0.007000 1.000 1.000 -09020210 9B Balsam pear 0.200000 1.000 1.000 -09020880 9B Chayote, fruit 0.200000 1.000 1.000 -09021020 9B Chinese waxgourd 0.008000 1.000 1.000 -

456

09021350 9B Cucumber 0.003901 1.000 1.000 19 -09023080 9B Pumpkin 0.008000 1.000 1.000 -09023090 9B Pumpkin, seed 0.008000 1.000 1.000 -09023560 9B Squash, summer 0.001010 1.000 1.000 29 -09023561 9B Squash, summer-babyfood 0.001010 1.000 1.000 29 -09023570 9B Squash, winter 0.001000 1.000 1.000 30 -09023571 9B Squash, winter-babyfood 0.001000 1.000 1.000 30 -10001060 10 Citrus citron 0.120000 1.000 1.000 -10001070 10 Citrus hybrids 0.120000 1.000 1.000 -10001080 10 Citrus, oil 0.120000 1.000 1.000 -10001800 10 Grapefruit 0.001018 1.000 1.000 31 -10001810 10 Grapefruit, juice 0.039000 1.000 2.100 -10001970 10 Kumquat 0.120000 1.000 1.000 -10001990 10 Lemon 0.120000 1.000 1.000 -10002000 10 Lemon, juice 0.120000 1.000 2.000 -10002001 10 Lemon, juice-babyfood 0.120000 1.000 2.000 -10002010 10 Lemon, peel 0.120000 1.000 1.160 -10002060 10 Lime 0.120000 1.000 1.000 -10002070 10 Lime, juice 0.120000 1.000 2.000 -10002071 10 Lime, juice-babyfood 0.120000 1.000 2.000 -10002400 10 Orange 0.001536 1.000 1.000 32 -10002410 10 Orange, juice 0.001581 1.000 1.000 33 -10002411 10 Orange, juice-babyfood 0.017000 1.000 1.000 33 -10002420 10 Orange, peel 0.120000 1.000 1.270 -10003070 10 Pummelo 0.120000 1.000 1.000 -10003690 10 Tangerine 0.120000 1.000 1.000 -10003700 10 Tangerine, juice 0.120000 1.000 2.300 -11000070 11 Apple, fruit with peel 0.005804 1.000 1.000 34 -11000080 11 Apple, peeled fruit 0.005804 1.000 1.000 34 -11000081 11 Apple, peeled fruit-babyfood 0.005804 1.000 1.000 34 -11000090 11 Apple, dried 0.490000 1.000 2.580 -11000091 11 Apple, dried-babyfood 0.490000 1.000 2.580 -11000100 11 Apple, juice 0.001937 1.000 1.000 35 -11000101 11 Apple, juice-babyfood 0.001937 1.000 1.000 35 -11000110 11 Apple, sauce 0.003683 1.000 1.000 36 -11000111 11 Apple, sauce-babyfood 0.003683 1.000 1.000 36 -11001290 11 Crabapple 0.490000 1.000 1.000 -11002100 11 Loquat 0.490000 1.000 1.000 -11002660 11 Pear 0.004646 1.000 1.000 37 -11002661 11 Pear-babyfood 0.004646 1.000 1.000 37 -11002670 11 Pear, dried 0.460000 1.000 2.580 -11002680 11 Pear, juice 0.004646 1.000 0.370 37 -11002681 11 Pear, juice-babyfood 0.004646 1.000 0.370 37 -11003100 11 Quince 0.490000 1.000 1.000 -12000120 12 Apricot 1.500000 1.000 1.000 77 -12000121 12 Apricot-babyfood 1.500000 1.000 1.000 77 -12000130 12 Apricot, dried 1.500000 1.000 6.000 -12000140 12 Apricot, juice 1.500000 1.000 1.000 -12000141 12 Apricot, juice-babyfood 1.500000 1.000 1.000 -12000900 12 Cherry 0.026422 1.000 1.000 38 -12000901 12 Cherry-babyfood 0.026422 1.000 1.000 38 -12000910 12 Cherry, juice 0.840000 1.000 1.500 -12000911 12 Cherry, juice-babyfood 0.840000 1.000 1.500 -12002300 12 Nectarine 0.010707 1.000 1.000 39 -12002600 12 Peach 110-Uncooked; Fresh or N/S; Cook Meth N/S 0.008962 1.000 1.000 40 - 120-Uncooked; Frozen; Cook Meth N/S 0.008962 1.000 1.000 40 - 130-Uncooked; Dried; Cook Meth N/S 0.008962 1.000 7.000 40 - 210-Cooked; Fresh or N/S; Cook Meth N/S 0.008962 1.000 1.000 40 - 211-Cooked; Fresh or N/S; Baked 0.008962 1.000 1.000 40 -

457

213-Cooked; Fresh or N/S; Fried 0.008962 1.000 1.000 40 - 221-Cooked; Frozen; Baked 0.008962 1.000 1.000 40 - 223-Cooked; Frozen; Fried 0.008962 1.000 1.000 40 - 240-Cooked; Canned; Cook Meth N/S 0.008962 1.000 1.000 40 -12002601 12 Peach-babyfood 0.008962 1.000 1.000 40 -12002610 12 Peach, dried 0.670000 1.000 7.000 -12002611 12 Peach, dried-babyfood 0.670000 1.000 7.000 -12002620 12 Peach, juice 0.670000 1.000 1.000 -12002621 12 Peach, juice-babyfood 0.670000 1.000 1.000 -12002850 12 Plum 0.006179 1.000 1.000 41 -12002851 12 Plum-babyfood 0.006179 1.000 1.000 41 -12002860 12 Plum, prune, fresh 0.006179 1.000 1.000 41 -12002861 12 Plum, prune, fresh-babyfood 0.006179 1.000 1.000 41 -12002870 12 Plum, prune, dried 0.005000 1.000 1.000 42 -12002871 12 Plum, prune, dried-babyfood 0.005000 1.000 1.000 42 -12002880 12 Plum, prune, juice 0.560000 1.000 1.400 -12002881 12 Plum, prune, juice-babyfood 0.560000 1.000 1.400 -13010550 13A Blackberry 0.092575 1.000 1.000 79 -13010560 13A Blackberry, juice 3.790000 1.000 1.000 79 -13010561 13A Blackberry, juice-babyfood 3.790000 1.000 1.000 79 -13010580 13A Boysenberry 3.790000 1.000 1.000 -13011420 13A Dewberry 3.790000 1.000 1.000 -13012080 13A Loganberry 3.790000 1.000 1.000 -13013200 13A Raspberry 0.092575 1.000 1.000 43 -13013201 13A Raspberry-babyfood 0.092575 1.000 1.000 43 -13013210 13A Raspberry, juice 3.790000 1.000 1.000 43 -13013211 13A Raspberry, juice-babyfood 3.790000 1.000 1.000 43 -13020570 13B Blueberry 0.094618 1.000 1.000 44 -13020571 13B Blueberry-babyfood 0.094618 1.000 1.000 44 -13021360 13B Currant 9.700000 1.000 1.000 -13021370 13B Currant, dried 9.700000 1.000 1.000 -13021490 13B Elderberry 9.700000 1.000 1.000 -13021740 13B Gooseberry 9.700000 1.000 1.000 -13021910 13B Huckleberry 9.700000 1.000 1.000 -14000030 14 Almond 0.007500 1.000 1.000 45 -14000031 14 Almond-babyfood 0.007500 1.000 1.000 45 -14000040 14 Almond, oil 0.015000 1.000 1.000 -14000041 14 Almond, oil-babyfood 0.015000 1.000 1.000 -14000590 14 Brazil nut 0.015000 1.000 1.000 -14000680 14 Butternut 0.015000 1.000 1.000 -14000810 14 Cashew 0.015000 1.000 1.000 -14000920 14 Chestnut 0.015000 1.000 1.000 -14001550 14 Filbert 0.015000 1.000 1.000 -14001560 14 Filbert, oil 0.015000 1.000 1.000 -14001850 14 Hickory nut 0.015000 1.000 1.000 -14002130 14 Macadamia nut 0.015000 1.000 1.000 -14002690 14 Pecan 0.015000 1.000 1.000 -14002820 14 Pistachio 0.015000 1.000 1.000 -14003910 14 Walnut 0.015000 1.000 1.000 -15001200 15 Corn, field, flour 0.008000 1.000 1.000 -15001201 15 Corn, field, flour-babyfood 0.008000 1.000 1.000 -15001210 15 Corn, field, meal 0.008000 1.000 1.000 -15001211 15 Corn, field, meal-babyfood 0.008000 1.000 1.000 -15001220 15 Corn, field, bran 0.008000 1.000 1.000 -15001230 15 Corn, field, starch 0.008000 1.000 1.000 -15001231 15 Corn, field, starch-babyfood 0.008000 1.000 1.000 -15001240 15 Corn, field, syrup 0.003000 1.000 1.500 49 -15001241 15 Corn, field, syrup-babyfood 0.003000 1.000 1.500 49 -15001250 15 Corn, field, oil 0.008000 1.000 0.250 -15001251 15 Corn, field, oil-babyfood 0.008000 1.000 1.000 -15001260 15 Corn, pop 0.008000 1.000 1.000 -15001270 15 Corn, sweet 0.004000 1.000 1.000 48 -15001271 15 Corn, sweet-babyfood 0.004000 1.000 1.000 48 -

458

15002260 15 Millet, grain 0.006000 1.000 1.000 -15003230 15 Rice, white 0.003548 1.000 0.030 50 -15003231 15 Rice, white-babyfood 0.003548 1.000 0.030 50 -15003240 15 Rice, brown 0.003548 1.000 1.000 50 -15003241 15 Rice, brown-babyfood 0.003548 1.000 1.000 50 -15003250 15 Rice, flour 0.040000 1.000 1.000 -15003251 15 Rice, flour-babyfood 0.040000 1.000 1.000 -15003260 15 Rice, bran 0.040000 1.000 0.400 -15003261 15 Rice, bran-babyfood 0.040000 1.000 0.400 -15003440 15 Sorghum, grain 0.008000 1.000 1.000 -15003450 15 Sorghum, syrup 0.008000 1.000 1.000 -15004010 15 Wheat, grain 0.003000 1.000 1.000 51 -15004011 15 Wheat, grain-babyfood 0.003000 1.000 1.000 51 -15004020 15 Wheat, flour 0.003000 1.000 1.000 52 -15004021 15 Wheat, flour-babyfood 0.003000 1.000 1.000 52 -15004030 15 Wheat, germ 0.006000 1.000 0.650 -15004040 15 Wheat, bran 0.006000 1.000 1.030 -19011440 19A Dillweed 0.093000 1.000 1.000 -19012490 19A Parsley, dried leaves 0.093000 1.000 1.000 -19012491 19A Parsley, dried leaves-babyfood 0.093000 1.000 1.000 -20001630 20 Flaxseed, oil 0.020000 1.000 1.000 -20003640 20 Sunflower, seed 0.012900 1.000 1.000 -20003650 20 Sunflower, oil 0.020000 1.000 1.000 -20003651 20 Sunflower, oil-babyfood 0.020000 1.000 1.000 -21000440 M Beef, meat 0.001800 1.000 1.000 -21000441 M Beef, meat-babyfood 0.001800 1.000 1.000 -21000450 M Beef, meat, dried 0.003600 1.000 1.920 -21000460 M Beef, meat byproducts 0.003600 1.000 1.000 -21000461 M Beef, meat byproducts-babyfood 0.003600 1.000 1.000 -21000470 M Beef, fat 0.007000 1.000 1.000 -21000471 M Beef,fat-babyfood 0.007000 1.000 1.000 -21000480 M Beef, kidney 0.003600 1.000 1.000 -21000490 M Beef, liver 0.001800 1.000 1.000 -21000491 M Beef, liver-babyfood 0.001800 1.000 1.000 -23001690 M Goat, meat 0.003600 1.000 1.000 -23001700 M Goat, meat byproducts 0.003600 1.000 1.000 -23001710 M Goat, fat 0.001400 1.000 1.000 -23001720 M Goat, kidney 0.003600 1.000 1.000 -23001730 M Goat, liver 0.003600 1.000 1.000 -24001890 M Horse, meat 0.003600 1.000 1.000 -25002900 M Pork, meat 0.000018 1.000 1.000 -25002901 M Pork, meat-babyfood 0.000018 1.000 1.000 -25002920 M Pork, meat byproducts 0.006600 1.000 1.000 -25002921 M Pork, meat byproducts-babyfood 0.006600 1.000 1.000 -25002930 M Pork, fat 0.003000 1.000 1.000 -25002931 M Pork, fat-babyfood 0.003000 1.000 1.000 -25002940 M Pork, kidney 0.006600 1.000 1.000 -25002950 M Pork, liver 0.006600 1.000 1.000 -26003390 M Sheep, meat 0.003600 1.000 1.000 -26003391 M Sheep, meat-babyfood 0.003600 1.000 1.000 -26003400 M Sheep, meat byproducts 0.003600 1.000 1.000 -26003410 M Sheep, fat 0.001400 1.000 1.000 -26003411 M Sheep, fat-babyfood 0.001400 1.000 1.000 -26003420 M Sheep, kidney 0.003600 1.000 1.000 -26003430 M Sheep, liver 0.003600 1.000 1.000 -27002220 D Milk, fat 0.008384 1.000 1.000 75 -27002221 D Milk, fat - baby food/infant for 0.008384 1.000 1.000 75 -27012230 D Milk, nonfat solids 0.000083 1.000 1.000 -27012231 D Milk, nonfat solids-baby food/in 0.000083 1.000 1.000 -27022240 D Milk, water 0.000043 1.000 1.000 70 -27022241 D Milk, water-babyfood/infant form 0.000043 1.000 1.000 70 -27032251 D Milk, sugar (lactose)-baby food/ 0.000083 1.000 1.000 -86011000 O Water, direct, tap 0.000009 1.000 1.000 63 -86012000 O Water, direct, bottled 0.000004 1.000 1.000 64 -86013000 O Water, direct, other 0.000019 1.000 1.000 -

459

86014000 O Water, direct, source-NS 0.000019 1.000 1.000 -86021000 O Water, indirect, tap 0.000009 1.000 1.000 63 -86022000 O Water, indirect, bottled 0.000004 1.000 1.000 64 -86023000 O Water, indirect, other 0.000019 1.000 1.000 -86024000 O Water, indirect, source-NS 0.000019 1.000 1.000 -95000190 O Asparagus 110-Uncooked; Fresh or N/S; Cook Meth N/S 0.004665 1.000 1.000 53 - 212-Cooked; Fresh or N/S; Boiled 0.004665 1.000 1.000 53 - 213-Cooked; Fresh or N/S; Fried 0.004665 1.000 1.000 53 - 222-Cooked; Frozen; Boiled 0.004665 1.000 1.000 53 - 242-Cooked; Canned; Boiled 0.004609 1.000 1.000 53 -95000230 O Banana 110-Uncooked; Fresh or N/S; Cook Meth N/S 0.001012 1.000 1.000 55 - 120-Uncooked; Frozen; Cook Meth N/S 0.001012 1.000 1.000 55 - 130-Uncooked; Dried; Cook Meth N/S 0.001012 1.000 3.900 55 - 211-Cooked; Fresh or N/S; Baked 0.001012 1.000 1.000 55 - 212-Cooked; Fresh or N/S; Boiled 0.001012 1.000 1.000 55 - 213-Cooked; Fresh or N/S; Fried 0.001012 1.000 1.000 55 - 223-Cooked; Frozen; Fried 0.001012 1.000 1.000 55 - 240-Cooked; Canned; Cook Meth N/S 0.001012 1.000 1.000 55 -95000730 O Cactus 0.025000 1.000 1.000 -95001300 O Cranberry 0.001267 1.000 1.000 56 -95001301 O Cranberry-babyfood 0.001267 1.000 1.000 56 -95001310 O Cranberry, dried 0.003000 1.000 1.000 -95001320 O Cranberry, juice 0.003000 1.000 1.100 -95001321 O Cranberry, juice-babyfood 0.003000 1.000 1.100 -95001750 O Grape 0.009150 1.000 1.000 57 -95001760 O Grape, juice 0.004838 1.000 1.000 58 -95001761 O Grape, juice-babyfood 0.004838 1.000 1.000 58 -95001780 O Grape, raisin 0.001050 1.000 1.000 59 -95001790 O Grape, wine and sherry 0.086000 1.000 1.000 59 -95002350 O Olive 9.830000 1.000 1.000 76 -95002360 O Olive, oil 0.077000 1.000 1.000 -95002630 O Peanut 0.010000 1.000 1.000 60 -95002640 O Peanut, butter 0.005000 1.000 1.000 60 -95002650 O Peanut, oil 0.010000 1.000 0.290 -95002790 O Pineapple 0.004927 1.000 0.540 61 -95002791 O Pineapple-babyfood 0.004927 1.000 0.540 61 -95002800 O Pineapple, dried 0.110000 1.000 5.000 -95002810 O Pineapple, juice 0.110000 1.000 0.540 -95002811 O Pineapple, juice-babyfood 0.110000 1.000 0.540 -95003590 O Strawberry 0.003625 1.000 1.000 62 -95003591 O Strawberry-babyfood 0.003625 1.000 1.000 62 -95003600 O Strawberry, juice 0.003625 1.000 1.000 62 -95003601 O Strawberry, juice-babyfood 0.003625 1.000 1.000 62 -

460

VII-2. Chronic Dietary Exposures and Risk EstimatesCalifornia Department of Pesticide Regulation Ver. 2.00DEEM-FCID Chronic analysis for CARBARYL (1994-98 data)Residue file name: H:\ARubin\Corel\CARBARYL\NEW DIETARY August 2009\DEEM files\cblchronic.R98 Adjustment factor #2 used.Analysis Date 12-10-2009/11:12:05 Residue file dated: 12-10-2009/10:32:53/14NOEL (Chronic) = .5 mg/kg bw/dayCOMMENT 1: Carbaryl chronic, run #4 - 12.10.09=============================================================================== Total exposure by population subgroup-------------------------------------------------------------------------------

Total Exposure ----------------------------------- Population mg/kg Percent Margin of Subgroup body wt/day of NOEL Exposr 1/-------------------------------------- ------------- --------- ---------U.S. Population (total) 0.000287 0.06% 1,741

U.S. Population (spring season) 0.000292 0.06% 1,713U.S. Population (summer season) 0.000281 0.06% 1,780U.S. Population (autumn season) 0.000278 0.06% 1,798U.S. Population (winter season) 0.000299 0.06% 1,672

Northeast region 0.000280 0.06% 1,787Midwest region 0.000291 0.06% 1,719Southern region 0.000240 0.05% 2,083Western region 0.000364 0.07% 1,373

Hispanics 0.000266 0.05% 1,882Non-hispanic whites 0.000291 0.06% 1,719Non-hispanic blacks 0.000251 0.05% 1,990Non-hisp/non-white/non-black 0.000379 0.08% 1,320

All infants (< 1 year) 0.000503 0.10% 995Nursing infants 0.000235 0.05% 2,128Non-nursing infants 0.000604 0.12% 827Children 1-6 yrs 0.000538 0.11% 929Children 7-12 yrs 0.000295 0.06% 1,696

Females 13-19 (not preg or nursing) 0.000207 0.04% 2,411Females 20+ (not preg or nursing) 0.000264 0.05% 1,897Females 13-50 yrs 0.000254 0.05% 1,972Females 13+ (preg/not nursing) 0.000193 0.04% 2,590Females 13+ (nursing) 0.000244 0.05% 2,046

Males 13-19 yrs 0.000244 0.05% 2,049Males 20+ yrs 0.000251 0.05% 1,994Seniors 55+ 0.000269 0.05% 1,862

Children 1-2 yrs 0.000655 0.13% 763Children 3-5 yrs 0.000483 0.10% 1,036Children 6-12 yrs 0.000322 0.06% 1,554Youth 13-19 yrs 0.000225 0.05% 2,219Adults 20-49 yrs 0.000253 0.05% 1,973Adults 50+ yrs 0.000263 0.05% 1,903Females 13-49 yrs 0.000249 0.05% 2,004

461

VII-3. Chronic Critical Commodity Contribution Analysis

California Department of Pesticide Regulation Ver. 2.00DEEM-FCID Chronic analysis for CARBARYL (1994-98 data)Residue file name: H:\ARubin\Corel\CARBARYL\NEW DIETARY August 2009\DEEM files\cblchronic.R98 Adjustment factor #2 used.Analysis Date 12-10-2009/11:12:19 Residue file dated: 12-10-2009/10:32:53/14NOEL (Chronic) = .5 mg/kg bw/dayCOMMENT 1: Carbaryl chronic, run #4 - 12.10.09=============================================================================== Critical Commodity Contribution Analysis for U.S. Population (total)

Total Exposure =.0002871 mg/kg bw/day

Crop groups with total exposure contribution > 5% Foods/Foodforms with exposure contribution > 5%-------------------------------------------------------------------------------

Crop group ------------ Exposure Analysis ----------- Food mg/kg |% of Total| Percent | Margin Foodform body wt/day| Exposure | of NOEL |of Exposr---------------------------------- -----------|----------|-------- |---------

Crop Group = (O) Other Olive (95002350): FoodForm N/S 0.0000938 32.66% 0.0% 5,332---------------------------------- -----------|----------|-------- |--------- Total for crop group 0.0001130 39.36% 0.0% 4,424

Crop Group = (5) Brassica (Cole) Leafy Vegetables Total for crop group 0.0000225 7.84% 0.0% 22,203

Crop Group = (5B) Brassica: Leafy Greens Total for crop group 0.0000223 7.76% 0.0% 22,440

Crop Group = (8) Fruiting Vegetables Total for crop group 0.0000210 7.30% 0.0% 23,859

Crop Group = (10) Citrus Fruits Total for crop group 0.0000206 7.18% 0.0% 24,238

Crop Group = (12) Stone Fruits Total for crop group 0.0000460 16.01% 0.0% 10,873

Total for crop groups listed above: 0.0002231 77.69% 0.0% 2,241-------------------------------------------------------------------------------

1. Margin of Exposure = NOEL / Dietary Exposure

462

Critical Commodity Contribution Analysis for Western region

Total Exposure =.0003641 mg/kg bw/day

Crop groups with total exposure contribution > 5% Foods/Foodforms with exposure contribution > 5%-------------------------------------------------------------------------------

Crop group ------------ Exposure Analysis ----------- Food mg/kg |% of Total| Percent | Margin Foodform body wt/day| Exposure | of NOEL |of Exposr---------------------------------- -----------|----------|-------- |---------

Crop Group = (O) Other Olive (95002350): FoodForm N/S 0.0001278 35.08% 0.0% 3,914---------------------------------- -----------|----------|-------- |--------- Total for crop group 0.0001540 42.30% 0.0% 3,246

Crop Group = (8) Fruiting Vegetables Pepper, nonbell (08002720): FoodForm N/S 0.0000221 6.07% 0.0% 22,636---------------------------------- -----------|----------|-------- |--------- Total for crop group 0.0000312 8.56% 0.0% 16,048

Crop Group = (9) Curcurbit Vegetables Total for crop group 0.0000210 5.76% 0.0% 23,840

Crop Group = (9A) Melons Total for crop group 0.0000197 5.42% 0.0% 25,338

Crop Group = (10) Citrus Fruits Total for crop group 0.0000215 5.91% 0.0% 23,243

Crop group ------------ Exposure Analysis ----------- Food mg/kg |% of Total| Percent | Margin Foodform body wt/day| Exposure | of NOEL |of Exposr---------------------------------- -----------|----------|-------- |---------

Crop Group = (12) Stone Fruits Apricot (12000120): FoodForm N/S 0.0000233 6.39% 0.0% 21,479---------------------------------- -----------|----------|-------- |--------- Total for crop group 0.0000560 15.39% 0.0% 8,924

Total for crop groups listed above: 0.0002837 77.91% 0.1% 1,762-------------------------------------------------------------------------------

1. Margin of Exposure = NOEL / Dietary Exposure

463

Critical Commodity Contribution Analysis for Hispanics

Total Exposure =.0002657 mg/kg bw/day

Crop groups with total exposure contribution > 5% Foods/Foodforms with exposure contribution > 5%-------------------------------------------------------------------------------

Crop group ------------ Exposure Analysis ----------- Food mg/kg |% of Total| Percent | Margin Foodform body wt/day| Exposure | of NOEL |of Exposr---------------------------------- -----------|----------|-------- |---------

Crop Group = (O) Other Olive (95002350): FoodForm N/S 0.0000826 31.08% 0.0% 6,055---------------------------------- -----------|----------|-------- |--------- Total for crop group 0.0000988 37.18% 0.0% 5,062

Crop Group = (8) Fruiting Vegetables Pepper, nonbell (08002720): FoodForm N/S 0.0000351 13.23% 0.0% 14,227---------------------------------- -----------|----------|-------- |--------- Total for crop group 0.0000471 17.71% 0.0% 10,626

Crop Group = (10) Citrus Fruits Total for crop group 0.0000242 9.09% 0.0% 20,696

Crop Group = (12) Stone Fruits Total for crop group 0.0000394 14.84% 0.0% 12,684

Crop Group = (15) Cereal Grains Total for crop group 0.0000157 5.91% 0.0% 31,846

Total for crop groups listed above: 0.0002251 84.72% 0.0% 2,221-------------------------------------------------------------------------------

1. Margin of Exposure = NOEL / Dietary Exposure

464

Critical Commodity Contribution Analysis for Non-hispanic whites

Total Exposure =.0002909 mg/kg bw/day

Crop groups with total exposure contribution > 5% Foods/Foodforms with exposure contribution > 5%-------------------------------------------------------------------------------

Crop group ------------ Exposure Analysis ----------- Food mg/kg |% of Total| Percent | Margin Foodform body wt/day| Exposure | of NOEL |of Exposr---------------------------------- -----------|----------|-------- |---------

Crop Group = (O) Other Olive (95002350): FoodForm N/S 0.0001062 36.51% 0.0% 4,708---------------------------------- -----------|----------|-------- |--------- Total for crop group 0.0001276 43.85% 0.0% 3,920

Crop Group = (8) Fruiting Vegetables Total for crop group 0.0000172 5.90% 0.0% 29,114

Crop Group = (10) Citrus Fruits Total for crop group 0.0000196 6.74% 0.0% 25,502

Crop Group = (12) Stone Fruits Total for crop group 0.0000484 16.63% 0.0% 10,339

Total for crop groups listed above: 0.0002127 73.12% 0.0% 2,351-------------------------------------------------------------------------------

1. Margin of Exposure = NOEL / Dietary Exposure

465

Critical Commodity Contribution Analysis for Non-hispanic blacks

Total Exposure =.0002512 mg/kg bw/day

Crop groups with total exposure contribution > 5% Foods/Foodforms with exposure contribution > 5%-------------------------------------------------------------------------------

Crop group ------------ Exposure Analysis ----------- Food mg/kg |% of Total| Percent | Margin Foodform body wt/day| Exposure | of NOEL |of Exposr---------------------------------- -----------|----------|-------- |---------

Crop Group = (O) Other Olive (95002350): FoodForm N/S 0.0000305 12.12% 0.0% 16,419---------------------------------- -----------|----------|-------- |--------- Total for crop group 0.0000416 16.55% 0.0% 12,027

Crop Group = (5) Brassica (Cole) Leafy Vegetables Mustard greens (05022290): FoodForm N/S 0.0000204 8.14% 0.0% 24,463 Turnip, greens (05023890): FoodForm N/S 0.0000599 23.83% 0.0% 8,352---------------------------------- -----------|----------|-------- |--------- Total for crop group 0.0000822 32.71% 0.0% 6,085

Crop Group = (5B) Brassica: Leafy Greens Mustard greens (05022290): FoodForm N/S 0.0000204 8.14% 0.0% 24,463 Turnip, greens (05023890): FoodForm N/S 0.0000599 23.83% 0.0% 8,352---------------------------------- -----------|----------|-------- |--------- Total for crop group 0.0000820 32.62% 0.0% 6,101

Crop Group = (8) Fruiting Vegetables Total for crop group 0.0000211 8.41% 0.0% 23,674

Crop Group = (10) Citrus Fruits Total for crop group 0.0000234 9.33% 0.0% 21,326

Crop group ------------ Exposure Analysis ----------- Food mg/kg |% of Total| Percent | Margin Foodform body wt/day| Exposure | of NOEL |of Exposr---------------------------------- -----------|----------|-------- |---------

Crop Group = (12) Stone Fruits Apricot, dried (12000130): FoodForm N/S 0.0000245 9.77% 0.0% 20,372---------------------------------- -----------|----------|-------- |--------- Total for crop group 0.0000410 16.31% 0.0% 12,206

Crop Group = (15) Cereal Grains Total for crop group 0.0000148 5.91% 0.0% 33,684

Total for crop groups listed above: 0.0002241 89.21% 0.0% 2,231-------------------------------------------------------------------------------

1. Margin of Exposure = NOEL / Dietary Exposure

466

Critical Commodity Contribution Analysis for Non-hisp/non-white/non-black

Total Exposure =.0003788 mg/kg bw/day

Crop groups with total exposure contribution > 5% Foods/Foodforms with exposure contribution > 5%-------------------------------------------------------------------------------

Crop group ------------ Exposure Analysis ----------- Food mg/kg |% of Total| Percent | Margin Foodform body wt/day| Exposure | of NOEL |of Exposr---------------------------------- -----------|----------|-------- |---------

Crop Group = (O) Other Olive (95002350): FoodForm N/S 0.0000966 25.51% 0.0% 5,174---------------------------------- -----------|----------|-------- |--------- Total for crop group 0.0001113 29.38% 0.0% 4,492

Crop Group = (5) Brassica (Cole) Leafy Vegetables Cabbage, Chinese, bok choy (05020700): FoodForm N/S 0.0000649 17.14% 0.0% 7,701 Mustard greens (05022290): FoodForm N/S 0.0000399 10.53% 0.0% 12,535---------------------------------- -----------|----------|-------- |--------- Total for crop group 0.0001094 28.87% 0.0% 4,572

Crop Group = (5B) Brassica: Leafy Greens Cabbage, Chinese, bok choy (05020700): FoodForm N/S 0.0000649 17.14% 0.0% 7,701 Mustard greens (05022290): FoodForm N/S 0.0000399 10.53% 0.0% 12,535---------------------------------- -----------|----------|-------- |--------- Total for crop group 0.0001089 28.74% 0.0% 4,593

Crop Group = (8) Fruiting Vegetables Total for crop group 0.0000200 5.29% 0.0% 24,951

Crop Group = (9) Curcurbit Vegetables Honeydew melon (09011870): FoodForm N/S 0.0000326 8.60% 0.0% 15,339---------------------------------- -----------|----------|-------- |--------- Total for crop group 0.0000368 9.72% 0.0% 13,579

Crop group ------------ Exposure Analysis ----------- Food mg/kg |% of Total| Percent | Margin Foodform body wt/day| Exposure | of NOEL |of Exposr---------------------------------- -----------|----------|-------- |---------

Crop Group = (9A) Melons Honeydew melon (09011870): FoodForm N/S 0.0000326 8.60% 0.0% 15,339---------------------------------- -----------|----------|-------- |--------- Total for crop group 0.0000332 8.76% 0.0% 15,060

Crop Group = (10) Citrus Fruits Total for crop group 0.0000209 5.53% 0.0% 23,888

Crop Group = (12) Stone Fruits Total for crop group 0.0000369 9.74% 0.0% 13,550

Total for crop groups listed above: 0.0003353 88.52% 0.1% 1,491

467

-------------------------------------------------------------------------------

1. Margin of Exposure = NOEL / Dietary Exposure

468

Critical Commodity Contribution Analysis for All infants (< 1 year)

Total Exposure =.0005027 mg/kg bw/day

Crop groups with total exposure contribution > 5% Foods/Foodforms with exposure contribution > 5%-------------------------------------------------------------------------------

Crop group ------------ Exposure Analysis ----------- Food mg/kg |% of Total| Percent | Margin Foodform body wt/day| Exposure | of NOEL |of Exposr---------------------------------- -----------|----------|-------- |---------

Crop Group = (12) Stone Fruits Apricot-babyfood (12000121): FoodForm N/S 0.0001473 29.31% 0.0% 3,394 Apricot, juice-babyfood (12000141): FoodForm N/S 0.0001344 26.74% 0.0% 3,720---------------------------------- -----------|----------|-------- |--------- Total for crop group 0.0003452 68.67% 0.1% 1,448

Crop Group = (13) Berries Total for crop group 0.0000282 5.62% 0.0% 17,713

Crop Group = (15) Cereal Grains Total for crop group 0.0000370 7.36% 0.0% 13,523

Total for crop groups listed above: 0.0004104 81.64% 0.1% 1,218-------------------------------------------------------------------------------

1. Margin of Exposure = NOEL / Dietary Exposure

469

Critical Commodity Contribution Analysis for Nursing infants

Total Exposure =.000235 mg/kg bw/day

Crop groups with total exposure contribution > 5% Foods/Foodforms with exposure contribution > 5%-------------------------------------------------------------------------------

Crop group ------------ Exposure Analysis ----------- Food mg/kg |% of Total| Percent | Margin Foodform body wt/day| Exposure | of NOEL |of Exposr---------------------------------- -----------|----------|-------- |---------

Crop Group = (11) Pome Fruits Total for crop group 0.0000142 6.02% 0.0% 35,316

Crop Group = (12) Stone Fruits Apricot-babyfood (12000121): FoodForm N/S 0.0000848 36.08% 0.0% 5,896 Apricot, juice-babyfood (12000141): FoodForm N/S 0.0000452 19.21% 0.0% 11,073---------------------------------- -----------|----------|-------- |--------- Total for crop group 0.0001527 64.98% 0.0% 3,274

Crop Group = (13) Berries Blackberry, juice-babyfood (13010561): FoodForm N/S 0.0000123 5.24% 0.0% 40,580---------------------------------- -----------|----------|-------- |--------- Total for crop group 0.0000216 9.17% 0.0% 23,193

Crop Group = (13A)Berries: Caneberry Group Blackberry, juice-babyfood (13010561): FoodForm N/S 0.0000123 5.24% 0.0% 40,580---------------------------------- -----------|----------|-------- |--------- Total for crop group 0.0000162 6.91% 0.0% 30,789

Crop Group = (15) Cereal Grains Rice, flour-babyfood (15003251): FoodForm N/S 0.0000164 6.96% 0.0% 30,565---------------------------------- -----------|----------|-------- |--------- Total for crop group 0.0000210 8.95% 0.0% 23,776

Total for crop groups listed above: 0.0002095 89.13% 0.0% 2,387-------------------------------------------------------------------------------

1. Margin of Exposure = NOEL / Dietary Exposure

470

Critical Commodity Contribution Analysis for Non-nursing infants

Total Exposure =.0006043 mg/kg bw/day

Crop groups with total exposure contribution > 5% Foods/Foodforms with exposure contribution > 5%-------------------------------------------------------------------------------

Crop group ------------ Exposure Analysis ----------- Food mg/kg |% of Total| Percent | Margin Foodform body wt/day| Exposure | of NOEL |of Exposr---------------------------------- -----------|----------|-------- |---------

Crop Group = (12) Stone Fruits Apricot-babyfood (12000121): FoodForm N/S 0.0001711 28.31% 0.0% 2,923 Apricot, juice-babyfood (12000141): FoodForm N/S 0.0001683 27.85% 0.0% 2,971---------------------------------- -----------|----------|-------- |--------- Total for crop group 0.0004183 69.22% 0.1% 1,195

Crop Group = (13) Berries Total for crop group 0.0000308 5.09% 0.0% 16,256

Crop Group = (15) Cereal Grains Total for crop group 0.0000430 7.12% 0.0% 11,621

Total for crop groups listed above: 0.0004920 81.43% 0.1% 1,016-------------------------------------------------------------------------------

1. Margin of Exposure = NOEL / Dietary Exposure

471

Critical Commodity Contribution Analysis for Females 13+ (preg/not nursing)

Total Exposure =.000193 mg/kg bw/day

Crop groups with total exposure contribution > 5% Foods/Foodforms with exposure contribution > 5%-------------------------------------------------------------------------------

Crop group ------------ Exposure Analysis ----------- Food mg/kg |% of Total| Percent | Margin Foodform body wt/day| Exposure | of NOEL |of Exposr---------------------------------- -----------|----------|-------- |---------

Crop Group = (O) Other Olive (95002350): FoodForm N/S 0.0000555 28.78% 0.0% 9,001---------------------------------- -----------|----------|-------- |--------- Total for crop group 0.0000652 33.79% 0.0% 7,666

Crop Group = (8) Fruiting Vegetables Pepper, nonbell (08002720): FoodForm N/S 0.0000495 25.63% 0.0% 10,107---------------------------------- -----------|----------|-------- |--------- Total for crop group 0.0000565 29.25% 0.0% 8,855

Crop Group = (10) Citrus Fruits Lemon, juice (10002000): FoodForm N/S 0.0000111 5.76% 0.0% 44,960---------------------------------- -----------|----------|-------- |--------- Total for crop group 0.0000166 8.62% 0.0% 30,057

Crop Group = (12) Stone Fruits Apricot, juice (12000140): FoodForm N/S 0.0000148 7.69% 0.0% 33,684---------------------------------- -----------|----------|-------- |--------- Total for crop group 0.0000232 12.04% 0.0% 21,521

Crop Group = (15) Cereal Grains Total for crop group 0.0000110 5.69% 0.0% 45,555

Total for crop groups listed above: 0.0001725 89.39% 0.0% 2,898-------------------------------------------------------------------------------

1. Margin of Exposure = NOEL / Dietary Exposure

472

Critical Commodity Contribution Analysis for Females 13+ (nursing)

Total Exposure =.0002443 mg/kg bw/day

Crop groups with total exposure contribution > 5% Foods/Foodforms with exposure contribution > 5%-------------------------------------------------------------------------------

Crop group ------------ Exposure Analysis ----------- Food mg/kg |% of Total| Percent | Margin Foodform body wt/day| Exposure | of NOEL |of Exposr---------------------------------- -----------|----------|-------- |---------

Crop Group = (O) Other Olive (95002350): FoodForm N/S 0.0000519 21.24% 0.0% 9,633 Pineapple, juice (95002810): FoodForm N/S 0.0000126 5.16% 0.0% 39,673---------------------------------- -----------|----------|-------- |--------- Total for crop group 0.0000689 28.19% 0.0% 7,259

Crop Group = (9) Curcurbit Vegetables Honeydew melon (09011870): FoodForm N/S 0.0000642 26.29% 0.0% 7,784---------------------------------- -----------|----------|-------- |--------- Total for crop group 0.0000653 26.72% 0.0% 7,657

Crop Group = (9A) Melons Honeydew melon (09011870): FoodForm N/S 0.0000642 26.29% 0.0% 7,784---------------------------------- -----------|----------|-------- |--------- Total for crop group 0.0000648 26.53% 0.0% 7,714

Crop Group = (10) Citrus Fruits Total for crop group 0.0000194 7.93% 0.0% 25,810

Crop Group = (12) Stone Fruits Apricot, dried (12000130): FoodForm N/S 0.0000249 10.18% 0.0% 20,100---------------------------------- -----------|----------|-------- |--------- Total for crop group 0.0000440 18.02% 0.0% 11,358

Total for crop groups listed above: 0.0001976 80.86% 0.0% 2,531-------------------------------------------------------------------------------

1. Margin of Exposure = NOEL / Dietary Exposure

473

Critical Commodity Contribution Analysis for Children 1-2 yrs

Total Exposure =.0006552 mg/kg bw/day

Crop groups with total exposure contribution > 5% Foods/Foodforms with exposure contribution > 5%-------------------------------------------------------------------------------

Crop group ------------ Exposure Analysis ----------- Food mg/kg |% of Total| Percent | Margin Foodform body wt/day| Exposure | of NOEL |of Exposr---------------------------------- -----------|----------|-------- |---------

Crop Group = (O) Other Olive (95002350): FoodForm N/S 0.0001206 18.41% 0.0% 4,145---------------------------------- -----------|----------|-------- |--------- Total for crop group 0.0001666 25.43% 0.0% 3,001

Crop Group = (10) Citrus Fruits Total for crop group 0.0000457 6.97% 0.0% 10,949

Crop Group = (12) Stone Fruits Apricot, dried (12000130): FoodForm N/S 0.0001107 16.89% 0.0% 4,517---------------------------------- -----------|----------|-------- |--------- Total for crop group 0.0002312 35.29% 0.0% 2,162

Crop Group = (13) Berries Total for crop group 0.0000432 6.59% 0.0% 11,581

Crop Group = (13A)Berries: Caneberry Group Total for crop group 0.0000381 5.82% 0.0% 13,123

Crop Group = (15) Cereal Grains Total for crop group 0.0000333 5.09% 0.0% 15,005

Total for crop groups listed above: 0.0005200 79.37% 0.1% 962-------------------------------------------------------------------------------

1. Margin of Exposure = NOEL / Dietary Exposure

474

Critical Commodity Contribution Analysis for Children 3-5 yrs

Total Exposure =.0004826 mg/kg bw/day

Crop groups with total exposure contribution > 5% Foods/Foodforms with exposure contribution > 5%-------------------------------------------------------------------------------

Crop group ------------ Exposure Analysis ----------- Food mg/kg |% of Total| Percent | Margin Foodform body wt/day| Exposure | of NOEL |of Exposr---------------------------------- -----------|----------|-------- |---------

Crop Group = (O) Other Olive (95002350): FoodForm N/S 0.0001238 25.66% 0.0% 4,038---------------------------------- -----------|----------|-------- |--------- Total for crop group 0.0001529 31.69% 0.0% 3,270

Crop Group = (5) Brassica (Cole) Leafy Vegetables Total for crop group 0.0000270 5.59% 0.0% 18,521

Crop Group = (5B) Brassica: Leafy Greens Total for crop group 0.0000268 5.54% 0.0% 18,687

Crop Group = (10) Citrus Fruits Total for crop group 0.0000450 9.32% 0.0% 11,122

Crop Group = (12) Stone Fruits Apricot (12000120): FoodForm N/S 0.0000280 5.80% 0.0% 17,862 Cherry, juice (12000910): FoodForm N/S 0.0000318 6.59% 0.0% 15,728---------------------------------- -----------|----------|-------- |--------- Total for crop group 0.0000916 18.99% 0.0% 5,456

Crop Group = (13) Berries Total for crop group 0.0000425 8.80% 0.0% 11,778

Crop group ------------ Exposure Analysis ----------- Food mg/kg |% of Total| Percent | Margin Foodform body wt/day| Exposure | of NOEL |of Exposr---------------------------------- -----------|----------|-------- |---------

Crop Group = (13A)Berries: Caneberry Group Total for crop group 0.0000294 6.09% 0.0% 16,998

Crop Group = (15) Cereal Grains Total for crop group 0.0000351 7.28% 0.0% 14,236

Total for crop groups listed above: 0.0003941 81.66% 0.1% 1,269-------------------------------------------------------------------------------

1. Margin of Exposure = NOEL / Dietary Exposure

475

Critical Commodity Contribution Analysis for Children 6-12 yrs

Total Exposure =.0003218 mg/kg bw/day

Crop groups with total exposure contribution > 5% Foods/Foodforms with exposure contribution > 5%-------------------------------------------------------------------------------

Crop group ------------ Exposure Analysis ----------- Food mg/kg |% of Total| Percent | Margin Foodform body wt/day| Exposure | of NOEL |of Exposr---------------------------------- -----------|----------|-------- |---------

Crop Group = (O) Other Olive (95002350): FoodForm N/S 0.0001024 31.81% 0.0% 4,885---------------------------------- -----------|----------|-------- |--------- Total for crop group 0.0001157 35.95% 0.0% 4,322

Crop Group = (8) Fruiting Vegetables Total for crop group 0.0000205 6.36% 0.0% 24,438

Crop Group = (9) Curcurbit Vegetables Total for crop group 0.0000161 5.00% 0.0% 31,063

Crop Group = (10) Citrus Fruits Total for crop group 0.0000283 8.81% 0.0% 17,641

Crop Group = (12) Stone Fruits Apricot (12000120): FoodForm N/S 0.0000184 5.73% 0.0% 27,114 Cherry, juice (12000910): FoodForm N/S 0.0000195 6.06% 0.0% 25,638---------------------------------- -----------|----------|-------- |--------- Total for crop group 0.0000540 16.77% 0.0% 9,266

Crop Group = (13) Berries Total for crop group 0.0000175 5.45% 0.0% 28,531

Crop group ------------ Exposure Analysis ----------- Food mg/kg |% of Total| Percent | Margin Foodform body wt/day| Exposure | of NOEL |of Exposr---------------------------------- -----------|----------|-------- |---------

Crop Group = (15) Cereal Grains Total for crop group 0.0000260 8.08% 0.0% 19,231

Total for crop groups listed above: 0.0002781 86.41% 0.1% 1,798-------------------------------------------------------------------------------

1. Margin of Exposure = NOEL / Dietary Exposure

476

Critical Commodity Contribution Analysis for Youth 13-19 yrs

Total Exposure =.0002253 mg/kg bw/day

Crop groups with total exposure contribution > 5% Foods/Foodforms with exposure contribution > 5%-------------------------------------------------------------------------------

Crop group ------------ Exposure Analysis ----------- Food mg/kg |% of Total| Percent | Margin Foodform body wt/day| Exposure | of NOEL |of Exposr---------------------------------- -----------|----------|-------- |---------

Crop Group = (O) Other Olive (95002350): FoodForm N/S 0.0000947 42.03% 0.0% 5,280---------------------------------- -----------|----------|-------- |--------- Total for crop group 0.0001000 44.39% 0.0% 5,000

Crop Group = (8) Fruiting Vegetables Total for crop group 0.0000149 6.63% 0.0% 33,459

Crop Group = (9) Curcurbit Vegetables Total for crop group 0.0000123 5.46% 0.0% 40,617

Crop Group = (9A) Melons Total for crop group 0.0000117 5.18% 0.0% 42,867

Crop Group = (10) Citrus Fruits Lemon, juice (10002000): FoodForm N/S 0.0000122 5.42% 0.0% 40,907---------------------------------- -----------|----------|-------- |--------- Total for crop group 0.0000222 9.85% 0.0% 22,524

Crop Group = (12) Stone Fruits Total for crop group 0.0000199 8.84% 0.0% 25,117

Crop group ------------ Exposure Analysis ----------- Food mg/kg |% of Total| Percent | Margin Foodform body wt/day| Exposure | of NOEL |of Exposr---------------------------------- -----------|----------|-------- |---------

Crop Group = (13) Berries Total for crop group 0.0000114 5.04% 0.0% 44,042

Crop Group = (15) Cereal Grains Total for crop group 0.0000164 7.27% 0.0% 30,512

Total for crop groups listed above: 0.0001971 87.48% 0.0% 2,537-------------------------------------------------------------------------------

1. Margin of Exposure = NOEL / Dietary Exposure

477

Critical Commodity Contribution Analysis for Adults 20-49 yrs

Total Exposure =.0002534 mg/kg bw/day

Crop groups with total exposure contribution > 5% Foods/Foodforms with exposure contribution > 5%-------------------------------------------------------------------------------

Crop group ------------ Exposure Analysis ----------- Food mg/kg |% of Total| Percent | Margin Foodform body wt/day| Exposure | of NOEL |of Exposr---------------------------------- -----------|----------|-------- |---------

Crop Group = (O) Other Grape, wine and sherry (95001790): FoodForm N/S 0.0000143 5.64% 0.0% 34,982 Olive (95002350): FoodForm N/S 0.0001108 43.72% 0.0% 4,513---------------------------------- -----------|----------|-------- |--------- Total for crop group 0.0001302 51.36% 0.0% 3,841

Crop Group = (5) Brassica (Cole) Leafy Vegetables Total for crop group 0.0000173 6.81% 0.0% 28,960

Crop Group = (5B) Brassica: Leafy Greens Total for crop group 0.0000170 6.72% 0.0% 29,343

Crop Group = (8) Fruiting Vegetables Pepper, nonbell (08002720): FoodForm N/S 0.0000154 6.08% 0.0% 32,431---------------------------------- -----------|----------|-------- |--------- Total for crop group 0.0000245 9.68% 0.0% 20,376

Crop Group = (10) Citrus Fruits Total for crop group 0.0000174 6.87% 0.0% 28,731

Crop Group = (12) Stone Fruits Total for crop group 0.0000221 8.70% 0.0% 22,669

Total for crop groups listed above: 0.0002114 83.43% 0.0% 2,365-------------------------------------------------------------------------------

1. Margin of Exposure = NOEL / Dietary Exposure

478

Critical Commodity Contribution Analysis for Adults 50+ yrs

Total Exposure =.0002628 mg/kg bw/day

Crop groups with total exposure contribution > 5% Foods/Foodforms with exposure contribution > 5%-------------------------------------------------------------------------------

Crop group ------------ Exposure Analysis ----------- Food mg/kg |% of Total| Percent | Margin Foodform body wt/day| Exposure | of NOEL |of Exposr---------------------------------- -----------|----------|-------- |---------

Crop Group = (O) Other Grape, wine and sherry (95001790): FoodForm N/S 0.0000175 6.67% 0.0% 28,510 Olive (95002350): FoodForm N/S 0.0000563 21.42% 0.0% 8,885---------------------------------- -----------|----------|-------- |--------- Total for crop group 0.0000781 29.70% 0.0% 6,406

Crop Group = (4) Leafy Vegetables (except Brassica) Total for crop group 0.0000202 7.67% 0.0% 24,812

Crop Group = (4B) Leaf Petioles Total for crop group 0.0000194 7.38% 0.0% 25,796

Crop Group = (5) Brassica (Cole) Leafy Vegetables Turnip, greens (05023890): FoodForm N/S 0.0000256 9.74% 0.0% 19,543---------------------------------- -----------|----------|-------- |--------- Total for crop group 0.0000403 15.33% 0.0% 12,410

Crop Group = (5B) Brassica: Leafy Greens Turnip, greens (05023890): FoodForm N/S 0.0000256 9.74% 0.0% 19,543---------------------------------- -----------|----------|-------- |--------- Total for crop group 0.0000400 15.21% 0.0% 12,511

Crop group ------------ Exposure Analysis ----------- Food mg/kg |% of Total| Percent | Margin Foodform body wt/day| Exposure | of NOEL |of Exposr---------------------------------- -----------|----------|-------- |---------

Crop Group = (8) Fruiting Vegetables Total for crop group 0.0000172 6.56% 0.0% 28,996

Crop Group = (9) Curcurbit Vegetables Honeydew melon (09011870): FoodForm N/S 0.0000164 6.25% 0.0% 30,438---------------------------------- -----------|----------|-------- |--------- Total for crop group 0.0000179 6.81% 0.0% 27,943

Crop Group = (9A) Melons Honeydew melon (09011870): FoodForm N/S 0.0000164 6.25% 0.0% 30,438---------------------------------- -----------|----------|-------- |--------- Total for crop group 0.0000174 6.64% 0.0% 28,670

Crop Group = (10) Citrus Fruits Total for crop group 0.0000154 5.85% 0.0% 32,508

479

Crop Group = (12) Stone Fruits Apricot (12000120): FoodForm N/S 0.0000169 6.43% 0.0% 29,609 Plum, prune, juice (12002880): FoodForm N/S 0.0000171 6.49% 0.0% 29,323---------------------------------- -----------|----------|-------- |--------- Total for crop group 0.0000467 17.77% 0.0% 10,708

Total for crop groups listed above: 0.0002357 89.70% 0.0% 2,121-------------------------------------------------------------------------------

1. Margin of Exposure = NOEL / Dietary Exposure

480

Critical Commodity Contribution Analysis for Females 13-49 yrs

Total Exposure =.0002495 mg/kg bw/day

Crop groups with total exposure contribution > 5% Foods/Foodforms with exposure contribution > 5%-------------------------------------------------------------------------------

Crop group ------------ Exposure Analysis ----------- Food mg/kg |% of Total| Percent | Margin Foodform body wt/day| Exposure | of NOEL |of Exposr---------------------------------- -----------|----------|-------- |---------

Crop Group = (O) Other Grape, wine and sherry (95001790): FoodForm N/S 0.0000145 5.80% 0.0% 34,575 Olive (95002350): FoodForm N/S 0.0001084 43.44% 0.0% 4,614---------------------------------- -----------|----------|-------- |--------- Total for crop group 0.0001287 51.57% 0.0% 3,886

Crop Group = (5) Brassica (Cole) Leafy Vegetables Total for crop group 0.0000142 5.70% 0.0% 35,161

Crop Group = (5B) Brassica: Leafy Greens Total for crop group 0.0000140 5.62% 0.0% 35,680

Crop Group = (8) Fruiting Vegetables Total for crop group 0.0000202 8.11% 0.0% 24,705

Crop Group = (10) Citrus Fruits Total for crop group 0.0000194 7.77% 0.0% 25,801

Crop Group = (12) Stone Fruits Total for crop group 0.0000244 9.77% 0.0% 20,511

Total for crop groups listed above: 0.0002069 82.92% 0.0% 2,417-------------------------------------------------------------------------------

1. Margin of Exposure = NOEL / Dietary Exposure

481

VII-4. Oncogenic Dietary Exposures and Risk Estimates

California Department of Pesticide Regulation Ver. 2.00DEEM-FCID Chronic analysis for CARBARYL (1994-98 data)Residue file name: H:\ARubin\Corel\CARBARYL\NEW DIETARY August 2009\DEEM files\cblchronic.R98 Adjustment factor #2 used.Analysis Date 01-20-2010/14:36:42 Residue file dated: 12-10-2009/10:32:53/14Q* = 0.0101 COMMENT 1: Final onco run using the recalculated value of 1.01x10e-2 as the potencyfactor.

=============================================================================== Total exposure by population subgroup-------------------------------------------------------------------------------

Total Exposure ----------------------------------- Population mg/kg Lifetime risk Subgroup body wt/day (Q*= .0101)-------------------------------------- ------------- -------------U.S. Population (total) 0.000287 2.90E-06

U.S. Population (spring season) 0.000292 2.95E-06U.S. Population (summer season) 0.000281 2.84E-06U.S. Population (autumn season) 0.000278 2.81E-06U.S. Population (winter season) 0.000299 3.02E-06

Northeast region 0.000280 2.83E-06Midwest region 0.000291 2.94E-06Southern region 0.000240 2.42E-06Western region 0.000364 3.68E-06

Hispanics 0.000266 2.68E-06Non-hispanic whites 0.000291 2.94E-06Non-hispanic blacks 0.000251 2.54E-06Non-hisp/non-white/non-black 0.000379 3.83E-06-------------------------------------------------------------------------------

482

Appendix VIII. The Environmental Fate of Carbaryl (EM Documents by Amrith Gunasekaraand by Sue Xu)

see following pages