cannabis. the use of marijuana for medicinal proposes dates back more then 5ooo years
TRANSCRIPT
Cannabis
Cannabis
The use of marijuana for medicinal proposes dates back more then 5ooo years
الحشاشون
bull الفاطميين عن انشقت إسماعيلية طائفة
من اتخذ الذي الصباح بن الحسن أسسهادعوته لنشر ا مركز) فارس في آلموت قلعة
هذه تميزت وقد دولته أركان وترسيخألهداف واالغتيال القتل باحتراف الطائفة
الحشاشين وكلمة متعصبة ودينية سياسيةAssassin في مختلفة بأشكال دخلت
أو خلسة القتل بمعنى األوروبي االستخدام المأجور المحترف القاتل بمعنى أو غدرا)
Cannabis sppCannabis is native to South Asia where it was first
cultivated and developed into the two varieties It is now a cultivated crop and an invasive in many parts of the world
There are three species known Cannabis sativa C indica and C rudelarisThe leaves are the most recognisable and well-
known aspect of the cannabis plant Despite the great degree of variation found naturally in local populations of cannabis the leaves do not alter greatly in appearance between varieties
What is Marijuana
Marijuana is the dried mix of flowers and leaves form the female Cannabis Sativa plant
Hashish is the resin or sap harvested from the plant
Hashish oil is the essential oil of the female Cannabis Sativa plant
Cannabis BiologyMajor Drug Component ndash delta-trans-tetrahydrocannabinol (THC)
- binds to specific receptors in brain
THC- produced in glands on leaves and flowers
-- female plants produce more glands
-- gland production stimulated by heat sunlight drought
-- sinsemilla (sin = without semilla = seeds) ndash particularly strong
Hashish ndash product - relatively pure resin
Glands THC
Tetrahydrocannabinol (THC)
Tetrahydrocannabinol (THC) is the main psychoactive substance found in the hemp plant Cannabis sativa or marijuana
Modes of Absorption
bull The most common method of absorption is smoking Either in a loosely rolled cigarette called a joint or through a pipe or water pipe
Smoking and the Body
THC enters the body through the Lungs
The smoke is inhaled and held in the lungsAll affect how much THC will enter the plasmaTHC crosses the blood barrier through the capillaries in the lungs
After inhalation THC can reach the brain in about 14 seconds
THC EffectsAlong with euphoria relaxation is another frequently reported effect in human
studies Other effects which vary dramatically from person to person include heightened sensory perception (eg brighter colors) laughter altered perception of time and increased appetite After a while the euphoria subsides and the user may feel sleepy or depressed In some users marijuana can produce anxiety fear distrust or panic
Marijuana users who have taken large doses of the drug may experience an acute psychosis which includes hallucinations delusions and a loss of the sense of personal identity Although the specific causes of these symptoms remain unknown they appear to occur more frequently when a high dose of cannabis is consumed in food or drink rather than smoked
The connection between marijuana use and cardiovascular risk could be partly explained by marijuanarsquos ability to increase heart rate (and blood pressuremdashat least initially) and reduce the bloods capacity to carry oxygen
ConthellipMarijuana use impairs a persons ability to form new memories and to shift
focus which can be particularly disruptive to young people who are at a stage in their lives when they should be absorbing critical information and skills needed to realize their full potential
THC also disrupts coordination and balance by affecting information processing in the cerebellum and basal gangliamdashparts of the brain that regulate balance posture coordination and reaction time Therefore learning doing complicated tasks participating in athletics and driving are also affected Not surprisingly because marijuana impairs judgment and motor coordination and slows reaction time an intoxicated person has an increased chance of being involved in and being responsible for an accident And in fact a recent systematic review of nine independent studies concluded that acute marijuana consumption is associated with a doubling of the risk of a motor vehicle crash especially of fatal collisions
Cannabinoids
Type-1 cannabinoid receptors (CB1) are found in CNS
Stimulation of these receptors has analgesic and anticonvulsant effects as well as antiemeticantinausea effects
The Cannabis High DescribedGives sensation of euphoria relaxation sexual
arousalbull1sttime users may experience nothing (experts say
they must learn to appreciate the effects)bullMarijuana tends to inhibit aggression and
accentuate caution as opposed to alcoholbull Marijuana causes time expansion (over estimation
of time elapsed)bullWorkers say that smoking marijuana help them to
work harder
Marijuana smoke can have harmful effects on the heart
1048766increased cardiac oxygen consumption1048766
Reduced blood flow in coronary arteries1048766
Increased carboxy-haemoglobin levels reducing the capacity of the blood to carry oxygen1048766
negative overall impact on atherosclerotic heart disease
Cannabinoidsbull Cannabinoids are a group of chemicals
which activate the bodyrsquos cannabinoid receptors Before other types were discovered the term referred to a unique group of secondary metabolites found in the Cannabis plant and now sometimes termed phytocannabinoids which are responsible for the plants peculiar pharmacological effects
CannabinoidsThere are three general types of
cannabinoids
1048766endogenous cannabinoids produced in the bodies of humans and other animals
1048766herbal cannabinoids present in the Cannabis plant
1048766synthetic cannabinoids similar compounds produced in a laboratory
Cannabinoid ReceptorsBeforethe 1980s it was often speculated that
cannabinoids produced their effects through non specific interaction with cell membranes instead of interacting with specific receptors
The discovery of the first cannabinoid receptors in the 1980s helped to resolve this debate These receptors are common in animals and have been found in mammals birds fishes and reptiles
There are currently two known types of cannabinoid receptors CB1 and CB2
CB1 ReceptorsFound primarily in the brain (specifically basal ganglia limbic
system including the hippocampus and cerebellum)1048766Most dense in brain regions involved with thinking and memory
attention and control of movement1048766Also present in both male and female reproductive systems as
well as in the lungs liver and kidneys1048766Appear to be responsible for the euphoric and anticonvulsive
effects of Cannabis1048766Essentially absent in the medulla oblongata the part of the brain
that is responsible for respiratory and cardiovascular functions
Thus there is no risk of respiratory or cardiovascular failure as there is with many other drugs
CB2 Receptor
CB2 receptors are almost exclusively found in the immune system (T cells macrophages B cells) with the greatest density in the spleen
1048766CB2 receptors appear to be responsible for the anti-inflammatory and possible other therapeutic effects of Cannabis
1048766Also expressed on peripheral nerve terminals
Endocannabinoids
Both Δ9-THC the psychoactive component of Cannabis sativa and anandamide an endogenous neurotransmitter in our brain bind o the same cannabinoid receptor
Drugs Can be Chemical Imposters(THC mimics a natural brain chemical)
Drug
THC
Brainrsquos Chemical
Anandamide
Withdrawal Symptoms
Marijuana addiction is also linked to a withdrawal syndrome that can make it hard to quit Symptoms include
bull irritabilitybull sleeping difficultiesbull cravingbull anxiety andbull increased aggression
WarningMarijuana is illegal in most places
Marijuana is in general much less dangerous than it is made out to be and certainly less harmful than legal drugs like tobacco and alcohol
It is impossible die from marijuana unlike most other illegal drugs and many legal ones
Most of the supposed scientific evidence for brain damage infertility etc have been disproven
- Cannabis
- Slide 2
- الحشاشون
- Cannabis spp
- Slide 5
- What is Marijuana
- Cannabis Biology
- Tetrahydrocannabinol (THC)
- Modes of Absorption
- Smoking and the Body
- THC Effects
- Conthellip
- Cannabinoids
- The Cannabis High Described
- Marijuana smoke can have harmful effects on the heart
- Cannabinoids
- Slide 17
- Cannabinoid Receptors
- CB1 Receptors
- CB2 Receptor
- Endocannabinoids
- Slide 22
- Withdrawal Symptoms
- Warning
-
Cannabis
The use of marijuana for medicinal proposes dates back more then 5ooo years
الحشاشون
bull الفاطميين عن انشقت إسماعيلية طائفة
من اتخذ الذي الصباح بن الحسن أسسهادعوته لنشر ا مركز) فارس في آلموت قلعة
هذه تميزت وقد دولته أركان وترسيخألهداف واالغتيال القتل باحتراف الطائفة
الحشاشين وكلمة متعصبة ودينية سياسيةAssassin في مختلفة بأشكال دخلت
أو خلسة القتل بمعنى األوروبي االستخدام المأجور المحترف القاتل بمعنى أو غدرا)
Cannabis sppCannabis is native to South Asia where it was first
cultivated and developed into the two varieties It is now a cultivated crop and an invasive in many parts of the world
There are three species known Cannabis sativa C indica and C rudelarisThe leaves are the most recognisable and well-
known aspect of the cannabis plant Despite the great degree of variation found naturally in local populations of cannabis the leaves do not alter greatly in appearance between varieties
What is Marijuana
Marijuana is the dried mix of flowers and leaves form the female Cannabis Sativa plant
Hashish is the resin or sap harvested from the plant
Hashish oil is the essential oil of the female Cannabis Sativa plant
Cannabis BiologyMajor Drug Component ndash delta-trans-tetrahydrocannabinol (THC)
- binds to specific receptors in brain
THC- produced in glands on leaves and flowers
-- female plants produce more glands
-- gland production stimulated by heat sunlight drought
-- sinsemilla (sin = without semilla = seeds) ndash particularly strong
Hashish ndash product - relatively pure resin
Glands THC
Tetrahydrocannabinol (THC)
Tetrahydrocannabinol (THC) is the main psychoactive substance found in the hemp plant Cannabis sativa or marijuana
Modes of Absorption
bull The most common method of absorption is smoking Either in a loosely rolled cigarette called a joint or through a pipe or water pipe
Smoking and the Body
THC enters the body through the Lungs
The smoke is inhaled and held in the lungsAll affect how much THC will enter the plasmaTHC crosses the blood barrier through the capillaries in the lungs
After inhalation THC can reach the brain in about 14 seconds
THC EffectsAlong with euphoria relaxation is another frequently reported effect in human
studies Other effects which vary dramatically from person to person include heightened sensory perception (eg brighter colors) laughter altered perception of time and increased appetite After a while the euphoria subsides and the user may feel sleepy or depressed In some users marijuana can produce anxiety fear distrust or panic
Marijuana users who have taken large doses of the drug may experience an acute psychosis which includes hallucinations delusions and a loss of the sense of personal identity Although the specific causes of these symptoms remain unknown they appear to occur more frequently when a high dose of cannabis is consumed in food or drink rather than smoked
The connection between marijuana use and cardiovascular risk could be partly explained by marijuanarsquos ability to increase heart rate (and blood pressuremdashat least initially) and reduce the bloods capacity to carry oxygen
ConthellipMarijuana use impairs a persons ability to form new memories and to shift
focus which can be particularly disruptive to young people who are at a stage in their lives when they should be absorbing critical information and skills needed to realize their full potential
THC also disrupts coordination and balance by affecting information processing in the cerebellum and basal gangliamdashparts of the brain that regulate balance posture coordination and reaction time Therefore learning doing complicated tasks participating in athletics and driving are also affected Not surprisingly because marijuana impairs judgment and motor coordination and slows reaction time an intoxicated person has an increased chance of being involved in and being responsible for an accident And in fact a recent systematic review of nine independent studies concluded that acute marijuana consumption is associated with a doubling of the risk of a motor vehicle crash especially of fatal collisions
Cannabinoids
Type-1 cannabinoid receptors (CB1) are found in CNS
Stimulation of these receptors has analgesic and anticonvulsant effects as well as antiemeticantinausea effects
The Cannabis High DescribedGives sensation of euphoria relaxation sexual
arousalbull1sttime users may experience nothing (experts say
they must learn to appreciate the effects)bullMarijuana tends to inhibit aggression and
accentuate caution as opposed to alcoholbull Marijuana causes time expansion (over estimation
of time elapsed)bullWorkers say that smoking marijuana help them to
work harder
Marijuana smoke can have harmful effects on the heart
1048766increased cardiac oxygen consumption1048766
Reduced blood flow in coronary arteries1048766
Increased carboxy-haemoglobin levels reducing the capacity of the blood to carry oxygen1048766
negative overall impact on atherosclerotic heart disease
Cannabinoidsbull Cannabinoids are a group of chemicals
which activate the bodyrsquos cannabinoid receptors Before other types were discovered the term referred to a unique group of secondary metabolites found in the Cannabis plant and now sometimes termed phytocannabinoids which are responsible for the plants peculiar pharmacological effects
CannabinoidsThere are three general types of
cannabinoids
1048766endogenous cannabinoids produced in the bodies of humans and other animals
1048766herbal cannabinoids present in the Cannabis plant
1048766synthetic cannabinoids similar compounds produced in a laboratory
Cannabinoid ReceptorsBeforethe 1980s it was often speculated that
cannabinoids produced their effects through non specific interaction with cell membranes instead of interacting with specific receptors
The discovery of the first cannabinoid receptors in the 1980s helped to resolve this debate These receptors are common in animals and have been found in mammals birds fishes and reptiles
There are currently two known types of cannabinoid receptors CB1 and CB2
CB1 ReceptorsFound primarily in the brain (specifically basal ganglia limbic
system including the hippocampus and cerebellum)1048766Most dense in brain regions involved with thinking and memory
attention and control of movement1048766Also present in both male and female reproductive systems as
well as in the lungs liver and kidneys1048766Appear to be responsible for the euphoric and anticonvulsive
effects of Cannabis1048766Essentially absent in the medulla oblongata the part of the brain
that is responsible for respiratory and cardiovascular functions
Thus there is no risk of respiratory or cardiovascular failure as there is with many other drugs
CB2 Receptor
CB2 receptors are almost exclusively found in the immune system (T cells macrophages B cells) with the greatest density in the spleen
1048766CB2 receptors appear to be responsible for the anti-inflammatory and possible other therapeutic effects of Cannabis
1048766Also expressed on peripheral nerve terminals
Endocannabinoids
Both Δ9-THC the psychoactive component of Cannabis sativa and anandamide an endogenous neurotransmitter in our brain bind o the same cannabinoid receptor
Drugs Can be Chemical Imposters(THC mimics a natural brain chemical)
Drug
THC
Brainrsquos Chemical
Anandamide
Withdrawal Symptoms
Marijuana addiction is also linked to a withdrawal syndrome that can make it hard to quit Symptoms include
bull irritabilitybull sleeping difficultiesbull cravingbull anxiety andbull increased aggression
WarningMarijuana is illegal in most places
Marijuana is in general much less dangerous than it is made out to be and certainly less harmful than legal drugs like tobacco and alcohol
It is impossible die from marijuana unlike most other illegal drugs and many legal ones
Most of the supposed scientific evidence for brain damage infertility etc have been disproven
- Cannabis
- Slide 2
- الحشاشون
- Cannabis spp
- Slide 5
- What is Marijuana
- Cannabis Biology
- Tetrahydrocannabinol (THC)
- Modes of Absorption
- Smoking and the Body
- THC Effects
- Conthellip
- Cannabinoids
- The Cannabis High Described
- Marijuana smoke can have harmful effects on the heart
- Cannabinoids
- Slide 17
- Cannabinoid Receptors
- CB1 Receptors
- CB2 Receptor
- Endocannabinoids
- Slide 22
- Withdrawal Symptoms
- Warning
-
الحشاشون
bull الفاطميين عن انشقت إسماعيلية طائفة
من اتخذ الذي الصباح بن الحسن أسسهادعوته لنشر ا مركز) فارس في آلموت قلعة
هذه تميزت وقد دولته أركان وترسيخألهداف واالغتيال القتل باحتراف الطائفة
الحشاشين وكلمة متعصبة ودينية سياسيةAssassin في مختلفة بأشكال دخلت
أو خلسة القتل بمعنى األوروبي االستخدام المأجور المحترف القاتل بمعنى أو غدرا)
Cannabis sppCannabis is native to South Asia where it was first
cultivated and developed into the two varieties It is now a cultivated crop and an invasive in many parts of the world
There are three species known Cannabis sativa C indica and C rudelarisThe leaves are the most recognisable and well-
known aspect of the cannabis plant Despite the great degree of variation found naturally in local populations of cannabis the leaves do not alter greatly in appearance between varieties
What is Marijuana
Marijuana is the dried mix of flowers and leaves form the female Cannabis Sativa plant
Hashish is the resin or sap harvested from the plant
Hashish oil is the essential oil of the female Cannabis Sativa plant
Cannabis BiologyMajor Drug Component ndash delta-trans-tetrahydrocannabinol (THC)
- binds to specific receptors in brain
THC- produced in glands on leaves and flowers
-- female plants produce more glands
-- gland production stimulated by heat sunlight drought
-- sinsemilla (sin = without semilla = seeds) ndash particularly strong
Hashish ndash product - relatively pure resin
Glands THC
Tetrahydrocannabinol (THC)
Tetrahydrocannabinol (THC) is the main psychoactive substance found in the hemp plant Cannabis sativa or marijuana
Modes of Absorption
bull The most common method of absorption is smoking Either in a loosely rolled cigarette called a joint or through a pipe or water pipe
Smoking and the Body
THC enters the body through the Lungs
The smoke is inhaled and held in the lungsAll affect how much THC will enter the plasmaTHC crosses the blood barrier through the capillaries in the lungs
After inhalation THC can reach the brain in about 14 seconds
THC EffectsAlong with euphoria relaxation is another frequently reported effect in human
studies Other effects which vary dramatically from person to person include heightened sensory perception (eg brighter colors) laughter altered perception of time and increased appetite After a while the euphoria subsides and the user may feel sleepy or depressed In some users marijuana can produce anxiety fear distrust or panic
Marijuana users who have taken large doses of the drug may experience an acute psychosis which includes hallucinations delusions and a loss of the sense of personal identity Although the specific causes of these symptoms remain unknown they appear to occur more frequently when a high dose of cannabis is consumed in food or drink rather than smoked
The connection between marijuana use and cardiovascular risk could be partly explained by marijuanarsquos ability to increase heart rate (and blood pressuremdashat least initially) and reduce the bloods capacity to carry oxygen
ConthellipMarijuana use impairs a persons ability to form new memories and to shift
focus which can be particularly disruptive to young people who are at a stage in their lives when they should be absorbing critical information and skills needed to realize their full potential
THC also disrupts coordination and balance by affecting information processing in the cerebellum and basal gangliamdashparts of the brain that regulate balance posture coordination and reaction time Therefore learning doing complicated tasks participating in athletics and driving are also affected Not surprisingly because marijuana impairs judgment and motor coordination and slows reaction time an intoxicated person has an increased chance of being involved in and being responsible for an accident And in fact a recent systematic review of nine independent studies concluded that acute marijuana consumption is associated with a doubling of the risk of a motor vehicle crash especially of fatal collisions
Cannabinoids
Type-1 cannabinoid receptors (CB1) are found in CNS
Stimulation of these receptors has analgesic and anticonvulsant effects as well as antiemeticantinausea effects
The Cannabis High DescribedGives sensation of euphoria relaxation sexual
arousalbull1sttime users may experience nothing (experts say
they must learn to appreciate the effects)bullMarijuana tends to inhibit aggression and
accentuate caution as opposed to alcoholbull Marijuana causes time expansion (over estimation
of time elapsed)bullWorkers say that smoking marijuana help them to
work harder
Marijuana smoke can have harmful effects on the heart
1048766increased cardiac oxygen consumption1048766
Reduced blood flow in coronary arteries1048766
Increased carboxy-haemoglobin levels reducing the capacity of the blood to carry oxygen1048766
negative overall impact on atherosclerotic heart disease
Cannabinoidsbull Cannabinoids are a group of chemicals
which activate the bodyrsquos cannabinoid receptors Before other types were discovered the term referred to a unique group of secondary metabolites found in the Cannabis plant and now sometimes termed phytocannabinoids which are responsible for the plants peculiar pharmacological effects
CannabinoidsThere are three general types of
cannabinoids
1048766endogenous cannabinoids produced in the bodies of humans and other animals
1048766herbal cannabinoids present in the Cannabis plant
1048766synthetic cannabinoids similar compounds produced in a laboratory
Cannabinoid ReceptorsBeforethe 1980s it was often speculated that
cannabinoids produced their effects through non specific interaction with cell membranes instead of interacting with specific receptors
The discovery of the first cannabinoid receptors in the 1980s helped to resolve this debate These receptors are common in animals and have been found in mammals birds fishes and reptiles
There are currently two known types of cannabinoid receptors CB1 and CB2
CB1 ReceptorsFound primarily in the brain (specifically basal ganglia limbic
system including the hippocampus and cerebellum)1048766Most dense in brain regions involved with thinking and memory
attention and control of movement1048766Also present in both male and female reproductive systems as
well as in the lungs liver and kidneys1048766Appear to be responsible for the euphoric and anticonvulsive
effects of Cannabis1048766Essentially absent in the medulla oblongata the part of the brain
that is responsible for respiratory and cardiovascular functions
Thus there is no risk of respiratory or cardiovascular failure as there is with many other drugs
CB2 Receptor
CB2 receptors are almost exclusively found in the immune system (T cells macrophages B cells) with the greatest density in the spleen
1048766CB2 receptors appear to be responsible for the anti-inflammatory and possible other therapeutic effects of Cannabis
1048766Also expressed on peripheral nerve terminals
Endocannabinoids
Both Δ9-THC the psychoactive component of Cannabis sativa and anandamide an endogenous neurotransmitter in our brain bind o the same cannabinoid receptor
Drugs Can be Chemical Imposters(THC mimics a natural brain chemical)
Drug
THC
Brainrsquos Chemical
Anandamide
Withdrawal Symptoms
Marijuana addiction is also linked to a withdrawal syndrome that can make it hard to quit Symptoms include
bull irritabilitybull sleeping difficultiesbull cravingbull anxiety andbull increased aggression
WarningMarijuana is illegal in most places
Marijuana is in general much less dangerous than it is made out to be and certainly less harmful than legal drugs like tobacco and alcohol
It is impossible die from marijuana unlike most other illegal drugs and many legal ones
Most of the supposed scientific evidence for brain damage infertility etc have been disproven
- Cannabis
- Slide 2
- الحشاشون
- Cannabis spp
- Slide 5
- What is Marijuana
- Cannabis Biology
- Tetrahydrocannabinol (THC)
- Modes of Absorption
- Smoking and the Body
- THC Effects
- Conthellip
- Cannabinoids
- The Cannabis High Described
- Marijuana smoke can have harmful effects on the heart
- Cannabinoids
- Slide 17
- Cannabinoid Receptors
- CB1 Receptors
- CB2 Receptor
- Endocannabinoids
- Slide 22
- Withdrawal Symptoms
- Warning
-
Cannabis sppCannabis is native to South Asia where it was first
cultivated and developed into the two varieties It is now a cultivated crop and an invasive in many parts of the world
There are three species known Cannabis sativa C indica and C rudelarisThe leaves are the most recognisable and well-
known aspect of the cannabis plant Despite the great degree of variation found naturally in local populations of cannabis the leaves do not alter greatly in appearance between varieties
What is Marijuana
Marijuana is the dried mix of flowers and leaves form the female Cannabis Sativa plant
Hashish is the resin or sap harvested from the plant
Hashish oil is the essential oil of the female Cannabis Sativa plant
Cannabis BiologyMajor Drug Component ndash delta-trans-tetrahydrocannabinol (THC)
- binds to specific receptors in brain
THC- produced in glands on leaves and flowers
-- female plants produce more glands
-- gland production stimulated by heat sunlight drought
-- sinsemilla (sin = without semilla = seeds) ndash particularly strong
Hashish ndash product - relatively pure resin
Glands THC
Tetrahydrocannabinol (THC)
Tetrahydrocannabinol (THC) is the main psychoactive substance found in the hemp plant Cannabis sativa or marijuana
Modes of Absorption
bull The most common method of absorption is smoking Either in a loosely rolled cigarette called a joint or through a pipe or water pipe
Smoking and the Body
THC enters the body through the Lungs
The smoke is inhaled and held in the lungsAll affect how much THC will enter the plasmaTHC crosses the blood barrier through the capillaries in the lungs
After inhalation THC can reach the brain in about 14 seconds
THC EffectsAlong with euphoria relaxation is another frequently reported effect in human
studies Other effects which vary dramatically from person to person include heightened sensory perception (eg brighter colors) laughter altered perception of time and increased appetite After a while the euphoria subsides and the user may feel sleepy or depressed In some users marijuana can produce anxiety fear distrust or panic
Marijuana users who have taken large doses of the drug may experience an acute psychosis which includes hallucinations delusions and a loss of the sense of personal identity Although the specific causes of these symptoms remain unknown they appear to occur more frequently when a high dose of cannabis is consumed in food or drink rather than smoked
The connection between marijuana use and cardiovascular risk could be partly explained by marijuanarsquos ability to increase heart rate (and blood pressuremdashat least initially) and reduce the bloods capacity to carry oxygen
ConthellipMarijuana use impairs a persons ability to form new memories and to shift
focus which can be particularly disruptive to young people who are at a stage in their lives when they should be absorbing critical information and skills needed to realize their full potential
THC also disrupts coordination and balance by affecting information processing in the cerebellum and basal gangliamdashparts of the brain that regulate balance posture coordination and reaction time Therefore learning doing complicated tasks participating in athletics and driving are also affected Not surprisingly because marijuana impairs judgment and motor coordination and slows reaction time an intoxicated person has an increased chance of being involved in and being responsible for an accident And in fact a recent systematic review of nine independent studies concluded that acute marijuana consumption is associated with a doubling of the risk of a motor vehicle crash especially of fatal collisions
Cannabinoids
Type-1 cannabinoid receptors (CB1) are found in CNS
Stimulation of these receptors has analgesic and anticonvulsant effects as well as antiemeticantinausea effects
The Cannabis High DescribedGives sensation of euphoria relaxation sexual
arousalbull1sttime users may experience nothing (experts say
they must learn to appreciate the effects)bullMarijuana tends to inhibit aggression and
accentuate caution as opposed to alcoholbull Marijuana causes time expansion (over estimation
of time elapsed)bullWorkers say that smoking marijuana help them to
work harder
Marijuana smoke can have harmful effects on the heart
1048766increased cardiac oxygen consumption1048766
Reduced blood flow in coronary arteries1048766
Increased carboxy-haemoglobin levels reducing the capacity of the blood to carry oxygen1048766
negative overall impact on atherosclerotic heart disease
Cannabinoidsbull Cannabinoids are a group of chemicals
which activate the bodyrsquos cannabinoid receptors Before other types were discovered the term referred to a unique group of secondary metabolites found in the Cannabis plant and now sometimes termed phytocannabinoids which are responsible for the plants peculiar pharmacological effects
CannabinoidsThere are three general types of
cannabinoids
1048766endogenous cannabinoids produced in the bodies of humans and other animals
1048766herbal cannabinoids present in the Cannabis plant
1048766synthetic cannabinoids similar compounds produced in a laboratory
Cannabinoid ReceptorsBeforethe 1980s it was often speculated that
cannabinoids produced their effects through non specific interaction with cell membranes instead of interacting with specific receptors
The discovery of the first cannabinoid receptors in the 1980s helped to resolve this debate These receptors are common in animals and have been found in mammals birds fishes and reptiles
There are currently two known types of cannabinoid receptors CB1 and CB2
CB1 ReceptorsFound primarily in the brain (specifically basal ganglia limbic
system including the hippocampus and cerebellum)1048766Most dense in brain regions involved with thinking and memory
attention and control of movement1048766Also present in both male and female reproductive systems as
well as in the lungs liver and kidneys1048766Appear to be responsible for the euphoric and anticonvulsive
effects of Cannabis1048766Essentially absent in the medulla oblongata the part of the brain
that is responsible for respiratory and cardiovascular functions
Thus there is no risk of respiratory or cardiovascular failure as there is with many other drugs
CB2 Receptor
CB2 receptors are almost exclusively found in the immune system (T cells macrophages B cells) with the greatest density in the spleen
1048766CB2 receptors appear to be responsible for the anti-inflammatory and possible other therapeutic effects of Cannabis
1048766Also expressed on peripheral nerve terminals
Endocannabinoids
Both Δ9-THC the psychoactive component of Cannabis sativa and anandamide an endogenous neurotransmitter in our brain bind o the same cannabinoid receptor
Drugs Can be Chemical Imposters(THC mimics a natural brain chemical)
Drug
THC
Brainrsquos Chemical
Anandamide
Withdrawal Symptoms
Marijuana addiction is also linked to a withdrawal syndrome that can make it hard to quit Symptoms include
bull irritabilitybull sleeping difficultiesbull cravingbull anxiety andbull increased aggression
WarningMarijuana is illegal in most places
Marijuana is in general much less dangerous than it is made out to be and certainly less harmful than legal drugs like tobacco and alcohol
It is impossible die from marijuana unlike most other illegal drugs and many legal ones
Most of the supposed scientific evidence for brain damage infertility etc have been disproven
- Cannabis
- Slide 2
- الحشاشون
- Cannabis spp
- Slide 5
- What is Marijuana
- Cannabis Biology
- Tetrahydrocannabinol (THC)
- Modes of Absorption
- Smoking and the Body
- THC Effects
- Conthellip
- Cannabinoids
- The Cannabis High Described
- Marijuana smoke can have harmful effects on the heart
- Cannabinoids
- Slide 17
- Cannabinoid Receptors
- CB1 Receptors
- CB2 Receptor
- Endocannabinoids
- Slide 22
- Withdrawal Symptoms
- Warning
-
What is Marijuana
Marijuana is the dried mix of flowers and leaves form the female Cannabis Sativa plant
Hashish is the resin or sap harvested from the plant
Hashish oil is the essential oil of the female Cannabis Sativa plant
Cannabis BiologyMajor Drug Component ndash delta-trans-tetrahydrocannabinol (THC)
- binds to specific receptors in brain
THC- produced in glands on leaves and flowers
-- female plants produce more glands
-- gland production stimulated by heat sunlight drought
-- sinsemilla (sin = without semilla = seeds) ndash particularly strong
Hashish ndash product - relatively pure resin
Glands THC
Tetrahydrocannabinol (THC)
Tetrahydrocannabinol (THC) is the main psychoactive substance found in the hemp plant Cannabis sativa or marijuana
Modes of Absorption
bull The most common method of absorption is smoking Either in a loosely rolled cigarette called a joint or through a pipe or water pipe
Smoking and the Body
THC enters the body through the Lungs
The smoke is inhaled and held in the lungsAll affect how much THC will enter the plasmaTHC crosses the blood barrier through the capillaries in the lungs
After inhalation THC can reach the brain in about 14 seconds
THC EffectsAlong with euphoria relaxation is another frequently reported effect in human
studies Other effects which vary dramatically from person to person include heightened sensory perception (eg brighter colors) laughter altered perception of time and increased appetite After a while the euphoria subsides and the user may feel sleepy or depressed In some users marijuana can produce anxiety fear distrust or panic
Marijuana users who have taken large doses of the drug may experience an acute psychosis which includes hallucinations delusions and a loss of the sense of personal identity Although the specific causes of these symptoms remain unknown they appear to occur more frequently when a high dose of cannabis is consumed in food or drink rather than smoked
The connection between marijuana use and cardiovascular risk could be partly explained by marijuanarsquos ability to increase heart rate (and blood pressuremdashat least initially) and reduce the bloods capacity to carry oxygen
ConthellipMarijuana use impairs a persons ability to form new memories and to shift
focus which can be particularly disruptive to young people who are at a stage in their lives when they should be absorbing critical information and skills needed to realize their full potential
THC also disrupts coordination and balance by affecting information processing in the cerebellum and basal gangliamdashparts of the brain that regulate balance posture coordination and reaction time Therefore learning doing complicated tasks participating in athletics and driving are also affected Not surprisingly because marijuana impairs judgment and motor coordination and slows reaction time an intoxicated person has an increased chance of being involved in and being responsible for an accident And in fact a recent systematic review of nine independent studies concluded that acute marijuana consumption is associated with a doubling of the risk of a motor vehicle crash especially of fatal collisions
Cannabinoids
Type-1 cannabinoid receptors (CB1) are found in CNS
Stimulation of these receptors has analgesic and anticonvulsant effects as well as antiemeticantinausea effects
The Cannabis High DescribedGives sensation of euphoria relaxation sexual
arousalbull1sttime users may experience nothing (experts say
they must learn to appreciate the effects)bullMarijuana tends to inhibit aggression and
accentuate caution as opposed to alcoholbull Marijuana causes time expansion (over estimation
of time elapsed)bullWorkers say that smoking marijuana help them to
work harder
Marijuana smoke can have harmful effects on the heart
1048766increased cardiac oxygen consumption1048766
Reduced blood flow in coronary arteries1048766
Increased carboxy-haemoglobin levels reducing the capacity of the blood to carry oxygen1048766
negative overall impact on atherosclerotic heart disease
Cannabinoidsbull Cannabinoids are a group of chemicals
which activate the bodyrsquos cannabinoid receptors Before other types were discovered the term referred to a unique group of secondary metabolites found in the Cannabis plant and now sometimes termed phytocannabinoids which are responsible for the plants peculiar pharmacological effects
CannabinoidsThere are three general types of
cannabinoids
1048766endogenous cannabinoids produced in the bodies of humans and other animals
1048766herbal cannabinoids present in the Cannabis plant
1048766synthetic cannabinoids similar compounds produced in a laboratory
Cannabinoid ReceptorsBeforethe 1980s it was often speculated that
cannabinoids produced their effects through non specific interaction with cell membranes instead of interacting with specific receptors
The discovery of the first cannabinoid receptors in the 1980s helped to resolve this debate These receptors are common in animals and have been found in mammals birds fishes and reptiles
There are currently two known types of cannabinoid receptors CB1 and CB2
CB1 ReceptorsFound primarily in the brain (specifically basal ganglia limbic
system including the hippocampus and cerebellum)1048766Most dense in brain regions involved with thinking and memory
attention and control of movement1048766Also present in both male and female reproductive systems as
well as in the lungs liver and kidneys1048766Appear to be responsible for the euphoric and anticonvulsive
effects of Cannabis1048766Essentially absent in the medulla oblongata the part of the brain
that is responsible for respiratory and cardiovascular functions
Thus there is no risk of respiratory or cardiovascular failure as there is with many other drugs
CB2 Receptor
CB2 receptors are almost exclusively found in the immune system (T cells macrophages B cells) with the greatest density in the spleen
1048766CB2 receptors appear to be responsible for the anti-inflammatory and possible other therapeutic effects of Cannabis
1048766Also expressed on peripheral nerve terminals
Endocannabinoids
Both Δ9-THC the psychoactive component of Cannabis sativa and anandamide an endogenous neurotransmitter in our brain bind o the same cannabinoid receptor
Drugs Can be Chemical Imposters(THC mimics a natural brain chemical)
Drug
THC
Brainrsquos Chemical
Anandamide
Withdrawal Symptoms
Marijuana addiction is also linked to a withdrawal syndrome that can make it hard to quit Symptoms include
bull irritabilitybull sleeping difficultiesbull cravingbull anxiety andbull increased aggression
WarningMarijuana is illegal in most places
Marijuana is in general much less dangerous than it is made out to be and certainly less harmful than legal drugs like tobacco and alcohol
It is impossible die from marijuana unlike most other illegal drugs and many legal ones
Most of the supposed scientific evidence for brain damage infertility etc have been disproven
- Cannabis
- Slide 2
- الحشاشون
- Cannabis spp
- Slide 5
- What is Marijuana
- Cannabis Biology
- Tetrahydrocannabinol (THC)
- Modes of Absorption
- Smoking and the Body
- THC Effects
- Conthellip
- Cannabinoids
- The Cannabis High Described
- Marijuana smoke can have harmful effects on the heart
- Cannabinoids
- Slide 17
- Cannabinoid Receptors
- CB1 Receptors
- CB2 Receptor
- Endocannabinoids
- Slide 22
- Withdrawal Symptoms
- Warning
-
Cannabis BiologyMajor Drug Component ndash delta-trans-tetrahydrocannabinol (THC)
- binds to specific receptors in brain
THC- produced in glands on leaves and flowers
-- female plants produce more glands
-- gland production stimulated by heat sunlight drought
-- sinsemilla (sin = without semilla = seeds) ndash particularly strong
Hashish ndash product - relatively pure resin
Glands THC
Tetrahydrocannabinol (THC)
Tetrahydrocannabinol (THC) is the main psychoactive substance found in the hemp plant Cannabis sativa or marijuana
Modes of Absorption
bull The most common method of absorption is smoking Either in a loosely rolled cigarette called a joint or through a pipe or water pipe
Smoking and the Body
THC enters the body through the Lungs
The smoke is inhaled and held in the lungsAll affect how much THC will enter the plasmaTHC crosses the blood barrier through the capillaries in the lungs
After inhalation THC can reach the brain in about 14 seconds
THC EffectsAlong with euphoria relaxation is another frequently reported effect in human
studies Other effects which vary dramatically from person to person include heightened sensory perception (eg brighter colors) laughter altered perception of time and increased appetite After a while the euphoria subsides and the user may feel sleepy or depressed In some users marijuana can produce anxiety fear distrust or panic
Marijuana users who have taken large doses of the drug may experience an acute psychosis which includes hallucinations delusions and a loss of the sense of personal identity Although the specific causes of these symptoms remain unknown they appear to occur more frequently when a high dose of cannabis is consumed in food or drink rather than smoked
The connection between marijuana use and cardiovascular risk could be partly explained by marijuanarsquos ability to increase heart rate (and blood pressuremdashat least initially) and reduce the bloods capacity to carry oxygen
ConthellipMarijuana use impairs a persons ability to form new memories and to shift
focus which can be particularly disruptive to young people who are at a stage in their lives when they should be absorbing critical information and skills needed to realize their full potential
THC also disrupts coordination and balance by affecting information processing in the cerebellum and basal gangliamdashparts of the brain that regulate balance posture coordination and reaction time Therefore learning doing complicated tasks participating in athletics and driving are also affected Not surprisingly because marijuana impairs judgment and motor coordination and slows reaction time an intoxicated person has an increased chance of being involved in and being responsible for an accident And in fact a recent systematic review of nine independent studies concluded that acute marijuana consumption is associated with a doubling of the risk of a motor vehicle crash especially of fatal collisions
Cannabinoids
Type-1 cannabinoid receptors (CB1) are found in CNS
Stimulation of these receptors has analgesic and anticonvulsant effects as well as antiemeticantinausea effects
The Cannabis High DescribedGives sensation of euphoria relaxation sexual
arousalbull1sttime users may experience nothing (experts say
they must learn to appreciate the effects)bullMarijuana tends to inhibit aggression and
accentuate caution as opposed to alcoholbull Marijuana causes time expansion (over estimation
of time elapsed)bullWorkers say that smoking marijuana help them to
work harder
Marijuana smoke can have harmful effects on the heart
1048766increased cardiac oxygen consumption1048766
Reduced blood flow in coronary arteries1048766
Increased carboxy-haemoglobin levels reducing the capacity of the blood to carry oxygen1048766
negative overall impact on atherosclerotic heart disease
Cannabinoidsbull Cannabinoids are a group of chemicals
which activate the bodyrsquos cannabinoid receptors Before other types were discovered the term referred to a unique group of secondary metabolites found in the Cannabis plant and now sometimes termed phytocannabinoids which are responsible for the plants peculiar pharmacological effects
CannabinoidsThere are three general types of
cannabinoids
1048766endogenous cannabinoids produced in the bodies of humans and other animals
1048766herbal cannabinoids present in the Cannabis plant
1048766synthetic cannabinoids similar compounds produced in a laboratory
Cannabinoid ReceptorsBeforethe 1980s it was often speculated that
cannabinoids produced their effects through non specific interaction with cell membranes instead of interacting with specific receptors
The discovery of the first cannabinoid receptors in the 1980s helped to resolve this debate These receptors are common in animals and have been found in mammals birds fishes and reptiles
There are currently two known types of cannabinoid receptors CB1 and CB2
CB1 ReceptorsFound primarily in the brain (specifically basal ganglia limbic
system including the hippocampus and cerebellum)1048766Most dense in brain regions involved with thinking and memory
attention and control of movement1048766Also present in both male and female reproductive systems as
well as in the lungs liver and kidneys1048766Appear to be responsible for the euphoric and anticonvulsive
effects of Cannabis1048766Essentially absent in the medulla oblongata the part of the brain
that is responsible for respiratory and cardiovascular functions
Thus there is no risk of respiratory or cardiovascular failure as there is with many other drugs
CB2 Receptor
CB2 receptors are almost exclusively found in the immune system (T cells macrophages B cells) with the greatest density in the spleen
1048766CB2 receptors appear to be responsible for the anti-inflammatory and possible other therapeutic effects of Cannabis
1048766Also expressed on peripheral nerve terminals
Endocannabinoids
Both Δ9-THC the psychoactive component of Cannabis sativa and anandamide an endogenous neurotransmitter in our brain bind o the same cannabinoid receptor
Drugs Can be Chemical Imposters(THC mimics a natural brain chemical)
Drug
THC
Brainrsquos Chemical
Anandamide
Withdrawal Symptoms
Marijuana addiction is also linked to a withdrawal syndrome that can make it hard to quit Symptoms include
bull irritabilitybull sleeping difficultiesbull cravingbull anxiety andbull increased aggression
WarningMarijuana is illegal in most places
Marijuana is in general much less dangerous than it is made out to be and certainly less harmful than legal drugs like tobacco and alcohol
It is impossible die from marijuana unlike most other illegal drugs and many legal ones
Most of the supposed scientific evidence for brain damage infertility etc have been disproven
- Cannabis
- Slide 2
- الحشاشون
- Cannabis spp
- Slide 5
- What is Marijuana
- Cannabis Biology
- Tetrahydrocannabinol (THC)
- Modes of Absorption
- Smoking and the Body
- THC Effects
- Conthellip
- Cannabinoids
- The Cannabis High Described
- Marijuana smoke can have harmful effects on the heart
- Cannabinoids
- Slide 17
- Cannabinoid Receptors
- CB1 Receptors
- CB2 Receptor
- Endocannabinoids
- Slide 22
- Withdrawal Symptoms
- Warning
-
Tetrahydrocannabinol (THC)
Tetrahydrocannabinol (THC) is the main psychoactive substance found in the hemp plant Cannabis sativa or marijuana
Modes of Absorption
bull The most common method of absorption is smoking Either in a loosely rolled cigarette called a joint or through a pipe or water pipe
Smoking and the Body
THC enters the body through the Lungs
The smoke is inhaled and held in the lungsAll affect how much THC will enter the plasmaTHC crosses the blood barrier through the capillaries in the lungs
After inhalation THC can reach the brain in about 14 seconds
THC EffectsAlong with euphoria relaxation is another frequently reported effect in human
studies Other effects which vary dramatically from person to person include heightened sensory perception (eg brighter colors) laughter altered perception of time and increased appetite After a while the euphoria subsides and the user may feel sleepy or depressed In some users marijuana can produce anxiety fear distrust or panic
Marijuana users who have taken large doses of the drug may experience an acute psychosis which includes hallucinations delusions and a loss of the sense of personal identity Although the specific causes of these symptoms remain unknown they appear to occur more frequently when a high dose of cannabis is consumed in food or drink rather than smoked
The connection between marijuana use and cardiovascular risk could be partly explained by marijuanarsquos ability to increase heart rate (and blood pressuremdashat least initially) and reduce the bloods capacity to carry oxygen
ConthellipMarijuana use impairs a persons ability to form new memories and to shift
focus which can be particularly disruptive to young people who are at a stage in their lives when they should be absorbing critical information and skills needed to realize their full potential
THC also disrupts coordination and balance by affecting information processing in the cerebellum and basal gangliamdashparts of the brain that regulate balance posture coordination and reaction time Therefore learning doing complicated tasks participating in athletics and driving are also affected Not surprisingly because marijuana impairs judgment and motor coordination and slows reaction time an intoxicated person has an increased chance of being involved in and being responsible for an accident And in fact a recent systematic review of nine independent studies concluded that acute marijuana consumption is associated with a doubling of the risk of a motor vehicle crash especially of fatal collisions
Cannabinoids
Type-1 cannabinoid receptors (CB1) are found in CNS
Stimulation of these receptors has analgesic and anticonvulsant effects as well as antiemeticantinausea effects
The Cannabis High DescribedGives sensation of euphoria relaxation sexual
arousalbull1sttime users may experience nothing (experts say
they must learn to appreciate the effects)bullMarijuana tends to inhibit aggression and
accentuate caution as opposed to alcoholbull Marijuana causes time expansion (over estimation
of time elapsed)bullWorkers say that smoking marijuana help them to
work harder
Marijuana smoke can have harmful effects on the heart
1048766increased cardiac oxygen consumption1048766
Reduced blood flow in coronary arteries1048766
Increased carboxy-haemoglobin levels reducing the capacity of the blood to carry oxygen1048766
negative overall impact on atherosclerotic heart disease
Cannabinoidsbull Cannabinoids are a group of chemicals
which activate the bodyrsquos cannabinoid receptors Before other types were discovered the term referred to a unique group of secondary metabolites found in the Cannabis plant and now sometimes termed phytocannabinoids which are responsible for the plants peculiar pharmacological effects
CannabinoidsThere are three general types of
cannabinoids
1048766endogenous cannabinoids produced in the bodies of humans and other animals
1048766herbal cannabinoids present in the Cannabis plant
1048766synthetic cannabinoids similar compounds produced in a laboratory
Cannabinoid ReceptorsBeforethe 1980s it was often speculated that
cannabinoids produced their effects through non specific interaction with cell membranes instead of interacting with specific receptors
The discovery of the first cannabinoid receptors in the 1980s helped to resolve this debate These receptors are common in animals and have been found in mammals birds fishes and reptiles
There are currently two known types of cannabinoid receptors CB1 and CB2
CB1 ReceptorsFound primarily in the brain (specifically basal ganglia limbic
system including the hippocampus and cerebellum)1048766Most dense in brain regions involved with thinking and memory
attention and control of movement1048766Also present in both male and female reproductive systems as
well as in the lungs liver and kidneys1048766Appear to be responsible for the euphoric and anticonvulsive
effects of Cannabis1048766Essentially absent in the medulla oblongata the part of the brain
that is responsible for respiratory and cardiovascular functions
Thus there is no risk of respiratory or cardiovascular failure as there is with many other drugs
CB2 Receptor
CB2 receptors are almost exclusively found in the immune system (T cells macrophages B cells) with the greatest density in the spleen
1048766CB2 receptors appear to be responsible for the anti-inflammatory and possible other therapeutic effects of Cannabis
1048766Also expressed on peripheral nerve terminals
Endocannabinoids
Both Δ9-THC the psychoactive component of Cannabis sativa and anandamide an endogenous neurotransmitter in our brain bind o the same cannabinoid receptor
Drugs Can be Chemical Imposters(THC mimics a natural brain chemical)
Drug
THC
Brainrsquos Chemical
Anandamide
Withdrawal Symptoms
Marijuana addiction is also linked to a withdrawal syndrome that can make it hard to quit Symptoms include
bull irritabilitybull sleeping difficultiesbull cravingbull anxiety andbull increased aggression
WarningMarijuana is illegal in most places
Marijuana is in general much less dangerous than it is made out to be and certainly less harmful than legal drugs like tobacco and alcohol
It is impossible die from marijuana unlike most other illegal drugs and many legal ones
Most of the supposed scientific evidence for brain damage infertility etc have been disproven
- Cannabis
- Slide 2
- الحشاشون
- Cannabis spp
- Slide 5
- What is Marijuana
- Cannabis Biology
- Tetrahydrocannabinol (THC)
- Modes of Absorption
- Smoking and the Body
- THC Effects
- Conthellip
- Cannabinoids
- The Cannabis High Described
- Marijuana smoke can have harmful effects on the heart
- Cannabinoids
- Slide 17
- Cannabinoid Receptors
- CB1 Receptors
- CB2 Receptor
- Endocannabinoids
- Slide 22
- Withdrawal Symptoms
- Warning
-
Modes of Absorption
bull The most common method of absorption is smoking Either in a loosely rolled cigarette called a joint or through a pipe or water pipe
Smoking and the Body
THC enters the body through the Lungs
The smoke is inhaled and held in the lungsAll affect how much THC will enter the plasmaTHC crosses the blood barrier through the capillaries in the lungs
After inhalation THC can reach the brain in about 14 seconds
THC EffectsAlong with euphoria relaxation is another frequently reported effect in human
studies Other effects which vary dramatically from person to person include heightened sensory perception (eg brighter colors) laughter altered perception of time and increased appetite After a while the euphoria subsides and the user may feel sleepy or depressed In some users marijuana can produce anxiety fear distrust or panic
Marijuana users who have taken large doses of the drug may experience an acute psychosis which includes hallucinations delusions and a loss of the sense of personal identity Although the specific causes of these symptoms remain unknown they appear to occur more frequently when a high dose of cannabis is consumed in food or drink rather than smoked
The connection between marijuana use and cardiovascular risk could be partly explained by marijuanarsquos ability to increase heart rate (and blood pressuremdashat least initially) and reduce the bloods capacity to carry oxygen
ConthellipMarijuana use impairs a persons ability to form new memories and to shift
focus which can be particularly disruptive to young people who are at a stage in their lives when they should be absorbing critical information and skills needed to realize their full potential
THC also disrupts coordination and balance by affecting information processing in the cerebellum and basal gangliamdashparts of the brain that regulate balance posture coordination and reaction time Therefore learning doing complicated tasks participating in athletics and driving are also affected Not surprisingly because marijuana impairs judgment and motor coordination and slows reaction time an intoxicated person has an increased chance of being involved in and being responsible for an accident And in fact a recent systematic review of nine independent studies concluded that acute marijuana consumption is associated with a doubling of the risk of a motor vehicle crash especially of fatal collisions
Cannabinoids
Type-1 cannabinoid receptors (CB1) are found in CNS
Stimulation of these receptors has analgesic and anticonvulsant effects as well as antiemeticantinausea effects
The Cannabis High DescribedGives sensation of euphoria relaxation sexual
arousalbull1sttime users may experience nothing (experts say
they must learn to appreciate the effects)bullMarijuana tends to inhibit aggression and
accentuate caution as opposed to alcoholbull Marijuana causes time expansion (over estimation
of time elapsed)bullWorkers say that smoking marijuana help them to
work harder
Marijuana smoke can have harmful effects on the heart
1048766increased cardiac oxygen consumption1048766
Reduced blood flow in coronary arteries1048766
Increased carboxy-haemoglobin levels reducing the capacity of the blood to carry oxygen1048766
negative overall impact on atherosclerotic heart disease
Cannabinoidsbull Cannabinoids are a group of chemicals
which activate the bodyrsquos cannabinoid receptors Before other types were discovered the term referred to a unique group of secondary metabolites found in the Cannabis plant and now sometimes termed phytocannabinoids which are responsible for the plants peculiar pharmacological effects
CannabinoidsThere are three general types of
cannabinoids
1048766endogenous cannabinoids produced in the bodies of humans and other animals
1048766herbal cannabinoids present in the Cannabis plant
1048766synthetic cannabinoids similar compounds produced in a laboratory
Cannabinoid ReceptorsBeforethe 1980s it was often speculated that
cannabinoids produced their effects through non specific interaction with cell membranes instead of interacting with specific receptors
The discovery of the first cannabinoid receptors in the 1980s helped to resolve this debate These receptors are common in animals and have been found in mammals birds fishes and reptiles
There are currently two known types of cannabinoid receptors CB1 and CB2
CB1 ReceptorsFound primarily in the brain (specifically basal ganglia limbic
system including the hippocampus and cerebellum)1048766Most dense in brain regions involved with thinking and memory
attention and control of movement1048766Also present in both male and female reproductive systems as
well as in the lungs liver and kidneys1048766Appear to be responsible for the euphoric and anticonvulsive
effects of Cannabis1048766Essentially absent in the medulla oblongata the part of the brain
that is responsible for respiratory and cardiovascular functions
Thus there is no risk of respiratory or cardiovascular failure as there is with many other drugs
CB2 Receptor
CB2 receptors are almost exclusively found in the immune system (T cells macrophages B cells) with the greatest density in the spleen
1048766CB2 receptors appear to be responsible for the anti-inflammatory and possible other therapeutic effects of Cannabis
1048766Also expressed on peripheral nerve terminals
Endocannabinoids
Both Δ9-THC the psychoactive component of Cannabis sativa and anandamide an endogenous neurotransmitter in our brain bind o the same cannabinoid receptor
Drugs Can be Chemical Imposters(THC mimics a natural brain chemical)
Drug
THC
Brainrsquos Chemical
Anandamide
Withdrawal Symptoms
Marijuana addiction is also linked to a withdrawal syndrome that can make it hard to quit Symptoms include
bull irritabilitybull sleeping difficultiesbull cravingbull anxiety andbull increased aggression
WarningMarijuana is illegal in most places
Marijuana is in general much less dangerous than it is made out to be and certainly less harmful than legal drugs like tobacco and alcohol
It is impossible die from marijuana unlike most other illegal drugs and many legal ones
Most of the supposed scientific evidence for brain damage infertility etc have been disproven
- Cannabis
- Slide 2
- الحشاشون
- Cannabis spp
- Slide 5
- What is Marijuana
- Cannabis Biology
- Tetrahydrocannabinol (THC)
- Modes of Absorption
- Smoking and the Body
- THC Effects
- Conthellip
- Cannabinoids
- The Cannabis High Described
- Marijuana smoke can have harmful effects on the heart
- Cannabinoids
- Slide 17
- Cannabinoid Receptors
- CB1 Receptors
- CB2 Receptor
- Endocannabinoids
- Slide 22
- Withdrawal Symptoms
- Warning
-
Smoking and the Body
THC enters the body through the Lungs
The smoke is inhaled and held in the lungsAll affect how much THC will enter the plasmaTHC crosses the blood barrier through the capillaries in the lungs
After inhalation THC can reach the brain in about 14 seconds
THC EffectsAlong with euphoria relaxation is another frequently reported effect in human
studies Other effects which vary dramatically from person to person include heightened sensory perception (eg brighter colors) laughter altered perception of time and increased appetite After a while the euphoria subsides and the user may feel sleepy or depressed In some users marijuana can produce anxiety fear distrust or panic
Marijuana users who have taken large doses of the drug may experience an acute psychosis which includes hallucinations delusions and a loss of the sense of personal identity Although the specific causes of these symptoms remain unknown they appear to occur more frequently when a high dose of cannabis is consumed in food or drink rather than smoked
The connection between marijuana use and cardiovascular risk could be partly explained by marijuanarsquos ability to increase heart rate (and blood pressuremdashat least initially) and reduce the bloods capacity to carry oxygen
ConthellipMarijuana use impairs a persons ability to form new memories and to shift
focus which can be particularly disruptive to young people who are at a stage in their lives when they should be absorbing critical information and skills needed to realize their full potential
THC also disrupts coordination and balance by affecting information processing in the cerebellum and basal gangliamdashparts of the brain that regulate balance posture coordination and reaction time Therefore learning doing complicated tasks participating in athletics and driving are also affected Not surprisingly because marijuana impairs judgment and motor coordination and slows reaction time an intoxicated person has an increased chance of being involved in and being responsible for an accident And in fact a recent systematic review of nine independent studies concluded that acute marijuana consumption is associated with a doubling of the risk of a motor vehicle crash especially of fatal collisions
Cannabinoids
Type-1 cannabinoid receptors (CB1) are found in CNS
Stimulation of these receptors has analgesic and anticonvulsant effects as well as antiemeticantinausea effects
The Cannabis High DescribedGives sensation of euphoria relaxation sexual
arousalbull1sttime users may experience nothing (experts say
they must learn to appreciate the effects)bullMarijuana tends to inhibit aggression and
accentuate caution as opposed to alcoholbull Marijuana causes time expansion (over estimation
of time elapsed)bullWorkers say that smoking marijuana help them to
work harder
Marijuana smoke can have harmful effects on the heart
1048766increased cardiac oxygen consumption1048766
Reduced blood flow in coronary arteries1048766
Increased carboxy-haemoglobin levels reducing the capacity of the blood to carry oxygen1048766
negative overall impact on atherosclerotic heart disease
Cannabinoidsbull Cannabinoids are a group of chemicals
which activate the bodyrsquos cannabinoid receptors Before other types were discovered the term referred to a unique group of secondary metabolites found in the Cannabis plant and now sometimes termed phytocannabinoids which are responsible for the plants peculiar pharmacological effects
CannabinoidsThere are three general types of
cannabinoids
1048766endogenous cannabinoids produced in the bodies of humans and other animals
1048766herbal cannabinoids present in the Cannabis plant
1048766synthetic cannabinoids similar compounds produced in a laboratory
Cannabinoid ReceptorsBeforethe 1980s it was often speculated that
cannabinoids produced their effects through non specific interaction with cell membranes instead of interacting with specific receptors
The discovery of the first cannabinoid receptors in the 1980s helped to resolve this debate These receptors are common in animals and have been found in mammals birds fishes and reptiles
There are currently two known types of cannabinoid receptors CB1 and CB2
CB1 ReceptorsFound primarily in the brain (specifically basal ganglia limbic
system including the hippocampus and cerebellum)1048766Most dense in brain regions involved with thinking and memory
attention and control of movement1048766Also present in both male and female reproductive systems as
well as in the lungs liver and kidneys1048766Appear to be responsible for the euphoric and anticonvulsive
effects of Cannabis1048766Essentially absent in the medulla oblongata the part of the brain
that is responsible for respiratory and cardiovascular functions
Thus there is no risk of respiratory or cardiovascular failure as there is with many other drugs
CB2 Receptor
CB2 receptors are almost exclusively found in the immune system (T cells macrophages B cells) with the greatest density in the spleen
1048766CB2 receptors appear to be responsible for the anti-inflammatory and possible other therapeutic effects of Cannabis
1048766Also expressed on peripheral nerve terminals
Endocannabinoids
Both Δ9-THC the psychoactive component of Cannabis sativa and anandamide an endogenous neurotransmitter in our brain bind o the same cannabinoid receptor
Drugs Can be Chemical Imposters(THC mimics a natural brain chemical)
Drug
THC
Brainrsquos Chemical
Anandamide
Withdrawal Symptoms
Marijuana addiction is also linked to a withdrawal syndrome that can make it hard to quit Symptoms include
bull irritabilitybull sleeping difficultiesbull cravingbull anxiety andbull increased aggression
WarningMarijuana is illegal in most places
Marijuana is in general much less dangerous than it is made out to be and certainly less harmful than legal drugs like tobacco and alcohol
It is impossible die from marijuana unlike most other illegal drugs and many legal ones
Most of the supposed scientific evidence for brain damage infertility etc have been disproven
- Cannabis
- Slide 2
- الحشاشون
- Cannabis spp
- Slide 5
- What is Marijuana
- Cannabis Biology
- Tetrahydrocannabinol (THC)
- Modes of Absorption
- Smoking and the Body
- THC Effects
- Conthellip
- Cannabinoids
- The Cannabis High Described
- Marijuana smoke can have harmful effects on the heart
- Cannabinoids
- Slide 17
- Cannabinoid Receptors
- CB1 Receptors
- CB2 Receptor
- Endocannabinoids
- Slide 22
- Withdrawal Symptoms
- Warning
-
THC EffectsAlong with euphoria relaxation is another frequently reported effect in human
studies Other effects which vary dramatically from person to person include heightened sensory perception (eg brighter colors) laughter altered perception of time and increased appetite After a while the euphoria subsides and the user may feel sleepy or depressed In some users marijuana can produce anxiety fear distrust or panic
Marijuana users who have taken large doses of the drug may experience an acute psychosis which includes hallucinations delusions and a loss of the sense of personal identity Although the specific causes of these symptoms remain unknown they appear to occur more frequently when a high dose of cannabis is consumed in food or drink rather than smoked
The connection between marijuana use and cardiovascular risk could be partly explained by marijuanarsquos ability to increase heart rate (and blood pressuremdashat least initially) and reduce the bloods capacity to carry oxygen
ConthellipMarijuana use impairs a persons ability to form new memories and to shift
focus which can be particularly disruptive to young people who are at a stage in their lives when they should be absorbing critical information and skills needed to realize their full potential
THC also disrupts coordination and balance by affecting information processing in the cerebellum and basal gangliamdashparts of the brain that regulate balance posture coordination and reaction time Therefore learning doing complicated tasks participating in athletics and driving are also affected Not surprisingly because marijuana impairs judgment and motor coordination and slows reaction time an intoxicated person has an increased chance of being involved in and being responsible for an accident And in fact a recent systematic review of nine independent studies concluded that acute marijuana consumption is associated with a doubling of the risk of a motor vehicle crash especially of fatal collisions
Cannabinoids
Type-1 cannabinoid receptors (CB1) are found in CNS
Stimulation of these receptors has analgesic and anticonvulsant effects as well as antiemeticantinausea effects
The Cannabis High DescribedGives sensation of euphoria relaxation sexual
arousalbull1sttime users may experience nothing (experts say
they must learn to appreciate the effects)bullMarijuana tends to inhibit aggression and
accentuate caution as opposed to alcoholbull Marijuana causes time expansion (over estimation
of time elapsed)bullWorkers say that smoking marijuana help them to
work harder
Marijuana smoke can have harmful effects on the heart
1048766increased cardiac oxygen consumption1048766
Reduced blood flow in coronary arteries1048766
Increased carboxy-haemoglobin levels reducing the capacity of the blood to carry oxygen1048766
negative overall impact on atherosclerotic heart disease
Cannabinoidsbull Cannabinoids are a group of chemicals
which activate the bodyrsquos cannabinoid receptors Before other types were discovered the term referred to a unique group of secondary metabolites found in the Cannabis plant and now sometimes termed phytocannabinoids which are responsible for the plants peculiar pharmacological effects
CannabinoidsThere are three general types of
cannabinoids
1048766endogenous cannabinoids produced in the bodies of humans and other animals
1048766herbal cannabinoids present in the Cannabis plant
1048766synthetic cannabinoids similar compounds produced in a laboratory
Cannabinoid ReceptorsBeforethe 1980s it was often speculated that
cannabinoids produced their effects through non specific interaction with cell membranes instead of interacting with specific receptors
The discovery of the first cannabinoid receptors in the 1980s helped to resolve this debate These receptors are common in animals and have been found in mammals birds fishes and reptiles
There are currently two known types of cannabinoid receptors CB1 and CB2
CB1 ReceptorsFound primarily in the brain (specifically basal ganglia limbic
system including the hippocampus and cerebellum)1048766Most dense in brain regions involved with thinking and memory
attention and control of movement1048766Also present in both male and female reproductive systems as
well as in the lungs liver and kidneys1048766Appear to be responsible for the euphoric and anticonvulsive
effects of Cannabis1048766Essentially absent in the medulla oblongata the part of the brain
that is responsible for respiratory and cardiovascular functions
Thus there is no risk of respiratory or cardiovascular failure as there is with many other drugs
CB2 Receptor
CB2 receptors are almost exclusively found in the immune system (T cells macrophages B cells) with the greatest density in the spleen
1048766CB2 receptors appear to be responsible for the anti-inflammatory and possible other therapeutic effects of Cannabis
1048766Also expressed on peripheral nerve terminals
Endocannabinoids
Both Δ9-THC the psychoactive component of Cannabis sativa and anandamide an endogenous neurotransmitter in our brain bind o the same cannabinoid receptor
Drugs Can be Chemical Imposters(THC mimics a natural brain chemical)
Drug
THC
Brainrsquos Chemical
Anandamide
Withdrawal Symptoms
Marijuana addiction is also linked to a withdrawal syndrome that can make it hard to quit Symptoms include
bull irritabilitybull sleeping difficultiesbull cravingbull anxiety andbull increased aggression
WarningMarijuana is illegal in most places
Marijuana is in general much less dangerous than it is made out to be and certainly less harmful than legal drugs like tobacco and alcohol
It is impossible die from marijuana unlike most other illegal drugs and many legal ones
Most of the supposed scientific evidence for brain damage infertility etc have been disproven
- Cannabis
- Slide 2
- الحشاشون
- Cannabis spp
- Slide 5
- What is Marijuana
- Cannabis Biology
- Tetrahydrocannabinol (THC)
- Modes of Absorption
- Smoking and the Body
- THC Effects
- Conthellip
- Cannabinoids
- The Cannabis High Described
- Marijuana smoke can have harmful effects on the heart
- Cannabinoids
- Slide 17
- Cannabinoid Receptors
- CB1 Receptors
- CB2 Receptor
- Endocannabinoids
- Slide 22
- Withdrawal Symptoms
- Warning
-
ConthellipMarijuana use impairs a persons ability to form new memories and to shift
focus which can be particularly disruptive to young people who are at a stage in their lives when they should be absorbing critical information and skills needed to realize their full potential
THC also disrupts coordination and balance by affecting information processing in the cerebellum and basal gangliamdashparts of the brain that regulate balance posture coordination and reaction time Therefore learning doing complicated tasks participating in athletics and driving are also affected Not surprisingly because marijuana impairs judgment and motor coordination and slows reaction time an intoxicated person has an increased chance of being involved in and being responsible for an accident And in fact a recent systematic review of nine independent studies concluded that acute marijuana consumption is associated with a doubling of the risk of a motor vehicle crash especially of fatal collisions
Cannabinoids
Type-1 cannabinoid receptors (CB1) are found in CNS
Stimulation of these receptors has analgesic and anticonvulsant effects as well as antiemeticantinausea effects
The Cannabis High DescribedGives sensation of euphoria relaxation sexual
arousalbull1sttime users may experience nothing (experts say
they must learn to appreciate the effects)bullMarijuana tends to inhibit aggression and
accentuate caution as opposed to alcoholbull Marijuana causes time expansion (over estimation
of time elapsed)bullWorkers say that smoking marijuana help them to
work harder
Marijuana smoke can have harmful effects on the heart
1048766increased cardiac oxygen consumption1048766
Reduced blood flow in coronary arteries1048766
Increased carboxy-haemoglobin levels reducing the capacity of the blood to carry oxygen1048766
negative overall impact on atherosclerotic heart disease
Cannabinoidsbull Cannabinoids are a group of chemicals
which activate the bodyrsquos cannabinoid receptors Before other types were discovered the term referred to a unique group of secondary metabolites found in the Cannabis plant and now sometimes termed phytocannabinoids which are responsible for the plants peculiar pharmacological effects
CannabinoidsThere are three general types of
cannabinoids
1048766endogenous cannabinoids produced in the bodies of humans and other animals
1048766herbal cannabinoids present in the Cannabis plant
1048766synthetic cannabinoids similar compounds produced in a laboratory
Cannabinoid ReceptorsBeforethe 1980s it was often speculated that
cannabinoids produced their effects through non specific interaction with cell membranes instead of interacting with specific receptors
The discovery of the first cannabinoid receptors in the 1980s helped to resolve this debate These receptors are common in animals and have been found in mammals birds fishes and reptiles
There are currently two known types of cannabinoid receptors CB1 and CB2
CB1 ReceptorsFound primarily in the brain (specifically basal ganglia limbic
system including the hippocampus and cerebellum)1048766Most dense in brain regions involved with thinking and memory
attention and control of movement1048766Also present in both male and female reproductive systems as
well as in the lungs liver and kidneys1048766Appear to be responsible for the euphoric and anticonvulsive
effects of Cannabis1048766Essentially absent in the medulla oblongata the part of the brain
that is responsible for respiratory and cardiovascular functions
Thus there is no risk of respiratory or cardiovascular failure as there is with many other drugs
CB2 Receptor
CB2 receptors are almost exclusively found in the immune system (T cells macrophages B cells) with the greatest density in the spleen
1048766CB2 receptors appear to be responsible for the anti-inflammatory and possible other therapeutic effects of Cannabis
1048766Also expressed on peripheral nerve terminals
Endocannabinoids
Both Δ9-THC the psychoactive component of Cannabis sativa and anandamide an endogenous neurotransmitter in our brain bind o the same cannabinoid receptor
Drugs Can be Chemical Imposters(THC mimics a natural brain chemical)
Drug
THC
Brainrsquos Chemical
Anandamide
Withdrawal Symptoms
Marijuana addiction is also linked to a withdrawal syndrome that can make it hard to quit Symptoms include
bull irritabilitybull sleeping difficultiesbull cravingbull anxiety andbull increased aggression
WarningMarijuana is illegal in most places
Marijuana is in general much less dangerous than it is made out to be and certainly less harmful than legal drugs like tobacco and alcohol
It is impossible die from marijuana unlike most other illegal drugs and many legal ones
Most of the supposed scientific evidence for brain damage infertility etc have been disproven
- Cannabis
- Slide 2
- الحشاشون
- Cannabis spp
- Slide 5
- What is Marijuana
- Cannabis Biology
- Tetrahydrocannabinol (THC)
- Modes of Absorption
- Smoking and the Body
- THC Effects
- Conthellip
- Cannabinoids
- The Cannabis High Described
- Marijuana smoke can have harmful effects on the heart
- Cannabinoids
- Slide 17
- Cannabinoid Receptors
- CB1 Receptors
- CB2 Receptor
- Endocannabinoids
- Slide 22
- Withdrawal Symptoms
- Warning
-
Cannabinoids
Type-1 cannabinoid receptors (CB1) are found in CNS
Stimulation of these receptors has analgesic and anticonvulsant effects as well as antiemeticantinausea effects
The Cannabis High DescribedGives sensation of euphoria relaxation sexual
arousalbull1sttime users may experience nothing (experts say
they must learn to appreciate the effects)bullMarijuana tends to inhibit aggression and
accentuate caution as opposed to alcoholbull Marijuana causes time expansion (over estimation
of time elapsed)bullWorkers say that smoking marijuana help them to
work harder
Marijuana smoke can have harmful effects on the heart
1048766increased cardiac oxygen consumption1048766
Reduced blood flow in coronary arteries1048766
Increased carboxy-haemoglobin levels reducing the capacity of the blood to carry oxygen1048766
negative overall impact on atherosclerotic heart disease
Cannabinoidsbull Cannabinoids are a group of chemicals
which activate the bodyrsquos cannabinoid receptors Before other types were discovered the term referred to a unique group of secondary metabolites found in the Cannabis plant and now sometimes termed phytocannabinoids which are responsible for the plants peculiar pharmacological effects
CannabinoidsThere are three general types of
cannabinoids
1048766endogenous cannabinoids produced in the bodies of humans and other animals
1048766herbal cannabinoids present in the Cannabis plant
1048766synthetic cannabinoids similar compounds produced in a laboratory
Cannabinoid ReceptorsBeforethe 1980s it was often speculated that
cannabinoids produced their effects through non specific interaction with cell membranes instead of interacting with specific receptors
The discovery of the first cannabinoid receptors in the 1980s helped to resolve this debate These receptors are common in animals and have been found in mammals birds fishes and reptiles
There are currently two known types of cannabinoid receptors CB1 and CB2
CB1 ReceptorsFound primarily in the brain (specifically basal ganglia limbic
system including the hippocampus and cerebellum)1048766Most dense in brain regions involved with thinking and memory
attention and control of movement1048766Also present in both male and female reproductive systems as
well as in the lungs liver and kidneys1048766Appear to be responsible for the euphoric and anticonvulsive
effects of Cannabis1048766Essentially absent in the medulla oblongata the part of the brain
that is responsible for respiratory and cardiovascular functions
Thus there is no risk of respiratory or cardiovascular failure as there is with many other drugs
CB2 Receptor
CB2 receptors are almost exclusively found in the immune system (T cells macrophages B cells) with the greatest density in the spleen
1048766CB2 receptors appear to be responsible for the anti-inflammatory and possible other therapeutic effects of Cannabis
1048766Also expressed on peripheral nerve terminals
Endocannabinoids
Both Δ9-THC the psychoactive component of Cannabis sativa and anandamide an endogenous neurotransmitter in our brain bind o the same cannabinoid receptor
Drugs Can be Chemical Imposters(THC mimics a natural brain chemical)
Drug
THC
Brainrsquos Chemical
Anandamide
Withdrawal Symptoms
Marijuana addiction is also linked to a withdrawal syndrome that can make it hard to quit Symptoms include
bull irritabilitybull sleeping difficultiesbull cravingbull anxiety andbull increased aggression
WarningMarijuana is illegal in most places
Marijuana is in general much less dangerous than it is made out to be and certainly less harmful than legal drugs like tobacco and alcohol
It is impossible die from marijuana unlike most other illegal drugs and many legal ones
Most of the supposed scientific evidence for brain damage infertility etc have been disproven
- Cannabis
- Slide 2
- الحشاشون
- Cannabis spp
- Slide 5
- What is Marijuana
- Cannabis Biology
- Tetrahydrocannabinol (THC)
- Modes of Absorption
- Smoking and the Body
- THC Effects
- Conthellip
- Cannabinoids
- The Cannabis High Described
- Marijuana smoke can have harmful effects on the heart
- Cannabinoids
- Slide 17
- Cannabinoid Receptors
- CB1 Receptors
- CB2 Receptor
- Endocannabinoids
- Slide 22
- Withdrawal Symptoms
- Warning
-
The Cannabis High DescribedGives sensation of euphoria relaxation sexual
arousalbull1sttime users may experience nothing (experts say
they must learn to appreciate the effects)bullMarijuana tends to inhibit aggression and
accentuate caution as opposed to alcoholbull Marijuana causes time expansion (over estimation
of time elapsed)bullWorkers say that smoking marijuana help them to
work harder
Marijuana smoke can have harmful effects on the heart
1048766increased cardiac oxygen consumption1048766
Reduced blood flow in coronary arteries1048766
Increased carboxy-haemoglobin levels reducing the capacity of the blood to carry oxygen1048766
negative overall impact on atherosclerotic heart disease
Cannabinoidsbull Cannabinoids are a group of chemicals
which activate the bodyrsquos cannabinoid receptors Before other types were discovered the term referred to a unique group of secondary metabolites found in the Cannabis plant and now sometimes termed phytocannabinoids which are responsible for the plants peculiar pharmacological effects
CannabinoidsThere are three general types of
cannabinoids
1048766endogenous cannabinoids produced in the bodies of humans and other animals
1048766herbal cannabinoids present in the Cannabis plant
1048766synthetic cannabinoids similar compounds produced in a laboratory
Cannabinoid ReceptorsBeforethe 1980s it was often speculated that
cannabinoids produced their effects through non specific interaction with cell membranes instead of interacting with specific receptors
The discovery of the first cannabinoid receptors in the 1980s helped to resolve this debate These receptors are common in animals and have been found in mammals birds fishes and reptiles
There are currently two known types of cannabinoid receptors CB1 and CB2
CB1 ReceptorsFound primarily in the brain (specifically basal ganglia limbic
system including the hippocampus and cerebellum)1048766Most dense in brain regions involved with thinking and memory
attention and control of movement1048766Also present in both male and female reproductive systems as
well as in the lungs liver and kidneys1048766Appear to be responsible for the euphoric and anticonvulsive
effects of Cannabis1048766Essentially absent in the medulla oblongata the part of the brain
that is responsible for respiratory and cardiovascular functions
Thus there is no risk of respiratory or cardiovascular failure as there is with many other drugs
CB2 Receptor
CB2 receptors are almost exclusively found in the immune system (T cells macrophages B cells) with the greatest density in the spleen
1048766CB2 receptors appear to be responsible for the anti-inflammatory and possible other therapeutic effects of Cannabis
1048766Also expressed on peripheral nerve terminals
Endocannabinoids
Both Δ9-THC the psychoactive component of Cannabis sativa and anandamide an endogenous neurotransmitter in our brain bind o the same cannabinoid receptor
Drugs Can be Chemical Imposters(THC mimics a natural brain chemical)
Drug
THC
Brainrsquos Chemical
Anandamide
Withdrawal Symptoms
Marijuana addiction is also linked to a withdrawal syndrome that can make it hard to quit Symptoms include
bull irritabilitybull sleeping difficultiesbull cravingbull anxiety andbull increased aggression
WarningMarijuana is illegal in most places
Marijuana is in general much less dangerous than it is made out to be and certainly less harmful than legal drugs like tobacco and alcohol
It is impossible die from marijuana unlike most other illegal drugs and many legal ones
Most of the supposed scientific evidence for brain damage infertility etc have been disproven
- Cannabis
- Slide 2
- الحشاشون
- Cannabis spp
- Slide 5
- What is Marijuana
- Cannabis Biology
- Tetrahydrocannabinol (THC)
- Modes of Absorption
- Smoking and the Body
- THC Effects
- Conthellip
- Cannabinoids
- The Cannabis High Described
- Marijuana smoke can have harmful effects on the heart
- Cannabinoids
- Slide 17
- Cannabinoid Receptors
- CB1 Receptors
- CB2 Receptor
- Endocannabinoids
- Slide 22
- Withdrawal Symptoms
- Warning
-
Marijuana smoke can have harmful effects on the heart
1048766increased cardiac oxygen consumption1048766
Reduced blood flow in coronary arteries1048766
Increased carboxy-haemoglobin levels reducing the capacity of the blood to carry oxygen1048766
negative overall impact on atherosclerotic heart disease
Cannabinoidsbull Cannabinoids are a group of chemicals
which activate the bodyrsquos cannabinoid receptors Before other types were discovered the term referred to a unique group of secondary metabolites found in the Cannabis plant and now sometimes termed phytocannabinoids which are responsible for the plants peculiar pharmacological effects
CannabinoidsThere are three general types of
cannabinoids
1048766endogenous cannabinoids produced in the bodies of humans and other animals
1048766herbal cannabinoids present in the Cannabis plant
1048766synthetic cannabinoids similar compounds produced in a laboratory
Cannabinoid ReceptorsBeforethe 1980s it was often speculated that
cannabinoids produced their effects through non specific interaction with cell membranes instead of interacting with specific receptors
The discovery of the first cannabinoid receptors in the 1980s helped to resolve this debate These receptors are common in animals and have been found in mammals birds fishes and reptiles
There are currently two known types of cannabinoid receptors CB1 and CB2
CB1 ReceptorsFound primarily in the brain (specifically basal ganglia limbic
system including the hippocampus and cerebellum)1048766Most dense in brain regions involved with thinking and memory
attention and control of movement1048766Also present in both male and female reproductive systems as
well as in the lungs liver and kidneys1048766Appear to be responsible for the euphoric and anticonvulsive
effects of Cannabis1048766Essentially absent in the medulla oblongata the part of the brain
that is responsible for respiratory and cardiovascular functions
Thus there is no risk of respiratory or cardiovascular failure as there is with many other drugs
CB2 Receptor
CB2 receptors are almost exclusively found in the immune system (T cells macrophages B cells) with the greatest density in the spleen
1048766CB2 receptors appear to be responsible for the anti-inflammatory and possible other therapeutic effects of Cannabis
1048766Also expressed on peripheral nerve terminals
Endocannabinoids
Both Δ9-THC the psychoactive component of Cannabis sativa and anandamide an endogenous neurotransmitter in our brain bind o the same cannabinoid receptor
Drugs Can be Chemical Imposters(THC mimics a natural brain chemical)
Drug
THC
Brainrsquos Chemical
Anandamide
Withdrawal Symptoms
Marijuana addiction is also linked to a withdrawal syndrome that can make it hard to quit Symptoms include
bull irritabilitybull sleeping difficultiesbull cravingbull anxiety andbull increased aggression
WarningMarijuana is illegal in most places
Marijuana is in general much less dangerous than it is made out to be and certainly less harmful than legal drugs like tobacco and alcohol
It is impossible die from marijuana unlike most other illegal drugs and many legal ones
Most of the supposed scientific evidence for brain damage infertility etc have been disproven
- Cannabis
- Slide 2
- الحشاشون
- Cannabis spp
- Slide 5
- What is Marijuana
- Cannabis Biology
- Tetrahydrocannabinol (THC)
- Modes of Absorption
- Smoking and the Body
- THC Effects
- Conthellip
- Cannabinoids
- The Cannabis High Described
- Marijuana smoke can have harmful effects on the heart
- Cannabinoids
- Slide 17
- Cannabinoid Receptors
- CB1 Receptors
- CB2 Receptor
- Endocannabinoids
- Slide 22
- Withdrawal Symptoms
- Warning
-
Cannabinoidsbull Cannabinoids are a group of chemicals
which activate the bodyrsquos cannabinoid receptors Before other types were discovered the term referred to a unique group of secondary metabolites found in the Cannabis plant and now sometimes termed phytocannabinoids which are responsible for the plants peculiar pharmacological effects
CannabinoidsThere are three general types of
cannabinoids
1048766endogenous cannabinoids produced in the bodies of humans and other animals
1048766herbal cannabinoids present in the Cannabis plant
1048766synthetic cannabinoids similar compounds produced in a laboratory
Cannabinoid ReceptorsBeforethe 1980s it was often speculated that
cannabinoids produced their effects through non specific interaction with cell membranes instead of interacting with specific receptors
The discovery of the first cannabinoid receptors in the 1980s helped to resolve this debate These receptors are common in animals and have been found in mammals birds fishes and reptiles
There are currently two known types of cannabinoid receptors CB1 and CB2
CB1 ReceptorsFound primarily in the brain (specifically basal ganglia limbic
system including the hippocampus and cerebellum)1048766Most dense in brain regions involved with thinking and memory
attention and control of movement1048766Also present in both male and female reproductive systems as
well as in the lungs liver and kidneys1048766Appear to be responsible for the euphoric and anticonvulsive
effects of Cannabis1048766Essentially absent in the medulla oblongata the part of the brain
that is responsible for respiratory and cardiovascular functions
Thus there is no risk of respiratory or cardiovascular failure as there is with many other drugs
CB2 Receptor
CB2 receptors are almost exclusively found in the immune system (T cells macrophages B cells) with the greatest density in the spleen
1048766CB2 receptors appear to be responsible for the anti-inflammatory and possible other therapeutic effects of Cannabis
1048766Also expressed on peripheral nerve terminals
Endocannabinoids
Both Δ9-THC the psychoactive component of Cannabis sativa and anandamide an endogenous neurotransmitter in our brain bind o the same cannabinoid receptor
Drugs Can be Chemical Imposters(THC mimics a natural brain chemical)
Drug
THC
Brainrsquos Chemical
Anandamide
Withdrawal Symptoms
Marijuana addiction is also linked to a withdrawal syndrome that can make it hard to quit Symptoms include
bull irritabilitybull sleeping difficultiesbull cravingbull anxiety andbull increased aggression
WarningMarijuana is illegal in most places
Marijuana is in general much less dangerous than it is made out to be and certainly less harmful than legal drugs like tobacco and alcohol
It is impossible die from marijuana unlike most other illegal drugs and many legal ones
Most of the supposed scientific evidence for brain damage infertility etc have been disproven
- Cannabis
- Slide 2
- الحشاشون
- Cannabis spp
- Slide 5
- What is Marijuana
- Cannabis Biology
- Tetrahydrocannabinol (THC)
- Modes of Absorption
- Smoking and the Body
- THC Effects
- Conthellip
- Cannabinoids
- The Cannabis High Described
- Marijuana smoke can have harmful effects on the heart
- Cannabinoids
- Slide 17
- Cannabinoid Receptors
- CB1 Receptors
- CB2 Receptor
- Endocannabinoids
- Slide 22
- Withdrawal Symptoms
- Warning
-
CannabinoidsThere are three general types of
cannabinoids
1048766endogenous cannabinoids produced in the bodies of humans and other animals
1048766herbal cannabinoids present in the Cannabis plant
1048766synthetic cannabinoids similar compounds produced in a laboratory
Cannabinoid ReceptorsBeforethe 1980s it was often speculated that
cannabinoids produced their effects through non specific interaction with cell membranes instead of interacting with specific receptors
The discovery of the first cannabinoid receptors in the 1980s helped to resolve this debate These receptors are common in animals and have been found in mammals birds fishes and reptiles
There are currently two known types of cannabinoid receptors CB1 and CB2
CB1 ReceptorsFound primarily in the brain (specifically basal ganglia limbic
system including the hippocampus and cerebellum)1048766Most dense in brain regions involved with thinking and memory
attention and control of movement1048766Also present in both male and female reproductive systems as
well as in the lungs liver and kidneys1048766Appear to be responsible for the euphoric and anticonvulsive
effects of Cannabis1048766Essentially absent in the medulla oblongata the part of the brain
that is responsible for respiratory and cardiovascular functions
Thus there is no risk of respiratory or cardiovascular failure as there is with many other drugs
CB2 Receptor
CB2 receptors are almost exclusively found in the immune system (T cells macrophages B cells) with the greatest density in the spleen
1048766CB2 receptors appear to be responsible for the anti-inflammatory and possible other therapeutic effects of Cannabis
1048766Also expressed on peripheral nerve terminals
Endocannabinoids
Both Δ9-THC the psychoactive component of Cannabis sativa and anandamide an endogenous neurotransmitter in our brain bind o the same cannabinoid receptor
Drugs Can be Chemical Imposters(THC mimics a natural brain chemical)
Drug
THC
Brainrsquos Chemical
Anandamide
Withdrawal Symptoms
Marijuana addiction is also linked to a withdrawal syndrome that can make it hard to quit Symptoms include
bull irritabilitybull sleeping difficultiesbull cravingbull anxiety andbull increased aggression
WarningMarijuana is illegal in most places
Marijuana is in general much less dangerous than it is made out to be and certainly less harmful than legal drugs like tobacco and alcohol
It is impossible die from marijuana unlike most other illegal drugs and many legal ones
Most of the supposed scientific evidence for brain damage infertility etc have been disproven
- Cannabis
- Slide 2
- الحشاشون
- Cannabis spp
- Slide 5
- What is Marijuana
- Cannabis Biology
- Tetrahydrocannabinol (THC)
- Modes of Absorption
- Smoking and the Body
- THC Effects
- Conthellip
- Cannabinoids
- The Cannabis High Described
- Marijuana smoke can have harmful effects on the heart
- Cannabinoids
- Slide 17
- Cannabinoid Receptors
- CB1 Receptors
- CB2 Receptor
- Endocannabinoids
- Slide 22
- Withdrawal Symptoms
- Warning
-
Cannabinoid ReceptorsBeforethe 1980s it was often speculated that
cannabinoids produced their effects through non specific interaction with cell membranes instead of interacting with specific receptors
The discovery of the first cannabinoid receptors in the 1980s helped to resolve this debate These receptors are common in animals and have been found in mammals birds fishes and reptiles
There are currently two known types of cannabinoid receptors CB1 and CB2
CB1 ReceptorsFound primarily in the brain (specifically basal ganglia limbic
system including the hippocampus and cerebellum)1048766Most dense in brain regions involved with thinking and memory
attention and control of movement1048766Also present in both male and female reproductive systems as
well as in the lungs liver and kidneys1048766Appear to be responsible for the euphoric and anticonvulsive
effects of Cannabis1048766Essentially absent in the medulla oblongata the part of the brain
that is responsible for respiratory and cardiovascular functions
Thus there is no risk of respiratory or cardiovascular failure as there is with many other drugs
CB2 Receptor
CB2 receptors are almost exclusively found in the immune system (T cells macrophages B cells) with the greatest density in the spleen
1048766CB2 receptors appear to be responsible for the anti-inflammatory and possible other therapeutic effects of Cannabis
1048766Also expressed on peripheral nerve terminals
Endocannabinoids
Both Δ9-THC the psychoactive component of Cannabis sativa and anandamide an endogenous neurotransmitter in our brain bind o the same cannabinoid receptor
Drugs Can be Chemical Imposters(THC mimics a natural brain chemical)
Drug
THC
Brainrsquos Chemical
Anandamide
Withdrawal Symptoms
Marijuana addiction is also linked to a withdrawal syndrome that can make it hard to quit Symptoms include
bull irritabilitybull sleeping difficultiesbull cravingbull anxiety andbull increased aggression
WarningMarijuana is illegal in most places
Marijuana is in general much less dangerous than it is made out to be and certainly less harmful than legal drugs like tobacco and alcohol
It is impossible die from marijuana unlike most other illegal drugs and many legal ones
Most of the supposed scientific evidence for brain damage infertility etc have been disproven
- Cannabis
- Slide 2
- الحشاشون
- Cannabis spp
- Slide 5
- What is Marijuana
- Cannabis Biology
- Tetrahydrocannabinol (THC)
- Modes of Absorption
- Smoking and the Body
- THC Effects
- Conthellip
- Cannabinoids
- The Cannabis High Described
- Marijuana smoke can have harmful effects on the heart
- Cannabinoids
- Slide 17
- Cannabinoid Receptors
- CB1 Receptors
- CB2 Receptor
- Endocannabinoids
- Slide 22
- Withdrawal Symptoms
- Warning
-
CB1 ReceptorsFound primarily in the brain (specifically basal ganglia limbic
system including the hippocampus and cerebellum)1048766Most dense in brain regions involved with thinking and memory
attention and control of movement1048766Also present in both male and female reproductive systems as
well as in the lungs liver and kidneys1048766Appear to be responsible for the euphoric and anticonvulsive
effects of Cannabis1048766Essentially absent in the medulla oblongata the part of the brain
that is responsible for respiratory and cardiovascular functions
Thus there is no risk of respiratory or cardiovascular failure as there is with many other drugs
CB2 Receptor
CB2 receptors are almost exclusively found in the immune system (T cells macrophages B cells) with the greatest density in the spleen
1048766CB2 receptors appear to be responsible for the anti-inflammatory and possible other therapeutic effects of Cannabis
1048766Also expressed on peripheral nerve terminals
Endocannabinoids
Both Δ9-THC the psychoactive component of Cannabis sativa and anandamide an endogenous neurotransmitter in our brain bind o the same cannabinoid receptor
Drugs Can be Chemical Imposters(THC mimics a natural brain chemical)
Drug
THC
Brainrsquos Chemical
Anandamide
Withdrawal Symptoms
Marijuana addiction is also linked to a withdrawal syndrome that can make it hard to quit Symptoms include
bull irritabilitybull sleeping difficultiesbull cravingbull anxiety andbull increased aggression
WarningMarijuana is illegal in most places
Marijuana is in general much less dangerous than it is made out to be and certainly less harmful than legal drugs like tobacco and alcohol
It is impossible die from marijuana unlike most other illegal drugs and many legal ones
Most of the supposed scientific evidence for brain damage infertility etc have been disproven
- Cannabis
- Slide 2
- الحشاشون
- Cannabis spp
- Slide 5
- What is Marijuana
- Cannabis Biology
- Tetrahydrocannabinol (THC)
- Modes of Absorption
- Smoking and the Body
- THC Effects
- Conthellip
- Cannabinoids
- The Cannabis High Described
- Marijuana smoke can have harmful effects on the heart
- Cannabinoids
- Slide 17
- Cannabinoid Receptors
- CB1 Receptors
- CB2 Receptor
- Endocannabinoids
- Slide 22
- Withdrawal Symptoms
- Warning
-
CB2 Receptor
CB2 receptors are almost exclusively found in the immune system (T cells macrophages B cells) with the greatest density in the spleen
1048766CB2 receptors appear to be responsible for the anti-inflammatory and possible other therapeutic effects of Cannabis
1048766Also expressed on peripheral nerve terminals
Endocannabinoids
Both Δ9-THC the psychoactive component of Cannabis sativa and anandamide an endogenous neurotransmitter in our brain bind o the same cannabinoid receptor
Drugs Can be Chemical Imposters(THC mimics a natural brain chemical)
Drug
THC
Brainrsquos Chemical
Anandamide
Withdrawal Symptoms
Marijuana addiction is also linked to a withdrawal syndrome that can make it hard to quit Symptoms include
bull irritabilitybull sleeping difficultiesbull cravingbull anxiety andbull increased aggression
WarningMarijuana is illegal in most places
Marijuana is in general much less dangerous than it is made out to be and certainly less harmful than legal drugs like tobacco and alcohol
It is impossible die from marijuana unlike most other illegal drugs and many legal ones
Most of the supposed scientific evidence for brain damage infertility etc have been disproven
- Cannabis
- Slide 2
- الحشاشون
- Cannabis spp
- Slide 5
- What is Marijuana
- Cannabis Biology
- Tetrahydrocannabinol (THC)
- Modes of Absorption
- Smoking and the Body
- THC Effects
- Conthellip
- Cannabinoids
- The Cannabis High Described
- Marijuana smoke can have harmful effects on the heart
- Cannabinoids
- Slide 17
- Cannabinoid Receptors
- CB1 Receptors
- CB2 Receptor
- Endocannabinoids
- Slide 22
- Withdrawal Symptoms
- Warning
-
Endocannabinoids
Both Δ9-THC the psychoactive component of Cannabis sativa and anandamide an endogenous neurotransmitter in our brain bind o the same cannabinoid receptor
Drugs Can be Chemical Imposters(THC mimics a natural brain chemical)
Drug
THC
Brainrsquos Chemical
Anandamide
Withdrawal Symptoms
Marijuana addiction is also linked to a withdrawal syndrome that can make it hard to quit Symptoms include
bull irritabilitybull sleeping difficultiesbull cravingbull anxiety andbull increased aggression
WarningMarijuana is illegal in most places
Marijuana is in general much less dangerous than it is made out to be and certainly less harmful than legal drugs like tobacco and alcohol
It is impossible die from marijuana unlike most other illegal drugs and many legal ones
Most of the supposed scientific evidence for brain damage infertility etc have been disproven
- Cannabis
- Slide 2
- الحشاشون
- Cannabis spp
- Slide 5
- What is Marijuana
- Cannabis Biology
- Tetrahydrocannabinol (THC)
- Modes of Absorption
- Smoking and the Body
- THC Effects
- Conthellip
- Cannabinoids
- The Cannabis High Described
- Marijuana smoke can have harmful effects on the heart
- Cannabinoids
- Slide 17
- Cannabinoid Receptors
- CB1 Receptors
- CB2 Receptor
- Endocannabinoids
- Slide 22
- Withdrawal Symptoms
- Warning
-
Drugs Can be Chemical Imposters(THC mimics a natural brain chemical)
Drug
THC
Brainrsquos Chemical
Anandamide
Withdrawal Symptoms
Marijuana addiction is also linked to a withdrawal syndrome that can make it hard to quit Symptoms include
bull irritabilitybull sleeping difficultiesbull cravingbull anxiety andbull increased aggression
WarningMarijuana is illegal in most places
Marijuana is in general much less dangerous than it is made out to be and certainly less harmful than legal drugs like tobacco and alcohol
It is impossible die from marijuana unlike most other illegal drugs and many legal ones
Most of the supposed scientific evidence for brain damage infertility etc have been disproven
- Cannabis
- Slide 2
- الحشاشون
- Cannabis spp
- Slide 5
- What is Marijuana
- Cannabis Biology
- Tetrahydrocannabinol (THC)
- Modes of Absorption
- Smoking and the Body
- THC Effects
- Conthellip
- Cannabinoids
- The Cannabis High Described
- Marijuana smoke can have harmful effects on the heart
- Cannabinoids
- Slide 17
- Cannabinoid Receptors
- CB1 Receptors
- CB2 Receptor
- Endocannabinoids
- Slide 22
- Withdrawal Symptoms
- Warning
-
Withdrawal Symptoms
Marijuana addiction is also linked to a withdrawal syndrome that can make it hard to quit Symptoms include
bull irritabilitybull sleeping difficultiesbull cravingbull anxiety andbull increased aggression
WarningMarijuana is illegal in most places
Marijuana is in general much less dangerous than it is made out to be and certainly less harmful than legal drugs like tobacco and alcohol
It is impossible die from marijuana unlike most other illegal drugs and many legal ones
Most of the supposed scientific evidence for brain damage infertility etc have been disproven
- Cannabis
- Slide 2
- الحشاشون
- Cannabis spp
- Slide 5
- What is Marijuana
- Cannabis Biology
- Tetrahydrocannabinol (THC)
- Modes of Absorption
- Smoking and the Body
- THC Effects
- Conthellip
- Cannabinoids
- The Cannabis High Described
- Marijuana smoke can have harmful effects on the heart
- Cannabinoids
- Slide 17
- Cannabinoid Receptors
- CB1 Receptors
- CB2 Receptor
- Endocannabinoids
- Slide 22
- Withdrawal Symptoms
- Warning
-
WarningMarijuana is illegal in most places
Marijuana is in general much less dangerous than it is made out to be and certainly less harmful than legal drugs like tobacco and alcohol
It is impossible die from marijuana unlike most other illegal drugs and many legal ones
Most of the supposed scientific evidence for brain damage infertility etc have been disproven
- Cannabis
- Slide 2
- الحشاشون
- Cannabis spp
- Slide 5
- What is Marijuana
- Cannabis Biology
- Tetrahydrocannabinol (THC)
- Modes of Absorption
- Smoking and the Body
- THC Effects
- Conthellip
- Cannabinoids
- The Cannabis High Described
- Marijuana smoke can have harmful effects on the heart
- Cannabinoids
- Slide 17
- Cannabinoid Receptors
- CB1 Receptors
- CB2 Receptor
- Endocannabinoids
- Slide 22
- Withdrawal Symptoms
- Warning
-