ca review on cns
TRANSCRIPT
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I. NEUROANATOMY
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Anatomy and Physiology
Gross anatomy
The nervous system is divided into the central
and peripheral nervous system
The Central nervous system consists of the
BRAIN and the Spinal Cord
The peripheral nervous system consists of theSpinal nerves and the cranial nerves
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BRAIN
The Brain is divided into 3 major areas:
1. Cerebrum
2. Brain Stem3. Cerebellum
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BRAIN- 1. Cerebrum
The largest part of the brain. Composed of:
2 hemispheres- the right and left, and the basal
ganglia.
The hemisphere is connected by corpus callosum, aband of fibers.
Each hemisphere is divided into 4 lobes.
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The 4 Lobes of the CEREBRUM
1. Frontal Lobe Largest lobe
location: frontof the skull.
contains theprimary motor cortexand responsible
for functions related to motor activity.
The left frontal lobe containsBrocas area(controlthe ability to produce spoken words)
The frontal lobecontrols higher intellectualfunction, awareness of self, and autonomic
responses related to emotions.
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2. Parietal
Sensory lobe
location: near the crown of the head.Contains theprimary sensory cortex.
One of its major function is to process sensory inputsuch asposition sense, touch, shape, and consistency
of objects.3. TemporalLocation: around the temples.
Contains theprimary auditory cortex.
Wernickes area is located on left temporal lobe. Contains the interpretative area where auditory, visual and
somatic input are integrated into thought and memory
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Lobes-cont.
4. Occipital
Location: lower back of the head
Contains theprimary visual cortex
Function: responsible for visual
interpretation.
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THE 4 LOBES
Frontal- motor /controlshigher intellectualfunction, awareness ofself, and autonomicresponses related toemotions.
Parietal- sensory
Temporal-auditory(Wernickes); Containsthe interpretative areawhere auditory, visualand somatic input areintegrated into thoughtand memory
Occipital-visual
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Structure of the Brain
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BRAIN-2. Brain Stem Consist of the midbrain, pons, and medulla oblongata.
Midbrain
-connects the pons and the cerebellum with the cerebralhemisphere, it contains sensory and motor pathways
-center for auditory and visual reflexes
Pons-connects the two halves of the cerebrum
- involved in the integration of movements in the right and leftsides of the body, and the transmission of motor informationfrom the higher brain areas and the spinal cord to the
cerebellum.medulla oblongata
- involved in the respiration, circulation, gastrointestinalfunctioning, coughing, sneezing, and swallowing.
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BRAIN-3. Cerebellum
Location: base of the brain.
Responsible for coordination, balance and
posture.
Damage to the cerebellum can resultinataxia, a
condition characterized by drunken-like
movements, severe tremors, and loss of
balance.
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Structures Protecting the Brain
The brain is contained in the rigid skull, whichprotects it from injury.
The meninges(fibrous connective tissuesthat cover the brain and the spinal cord)
provide protection, support and nourishmentto the brain and the spinal cord.
Layers of the meninges:
1.dura mater
2.arachnoid
3.pia mater.
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CSF
CSF- provide a cushion, provide nutrition,maintain normal ICP, remove metabolic waste.
Composition colorless, odorless fluid containing
glucose, electrolytes, oxygen, water, small amountof carbon monoxide and few leukocytes.
Produced in the choroid plexus of the ventricles.
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BLOOD SUPPLY TO THE CNS
1/3 of the cardiac output
From 2 vertebral artery and one internal
carotid arteries
Circle of willis
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Spinal Cord
Approximately 45 cm long (18 inches) long.
Acts as apassageway for condition of
sensory information from the periphery
of the body to the brain (via afferent
nerve fibers).
Serve as the connection between the brain and
the periphery.Mediates the reflexes.
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Spinal Nerves Spinal nerves
31 pairs 8 cervical, 12 thoracic, 5 lumbar
5 sacral, 1 coccygeal
Two roots
Ventral root (motor)
Carry impulses from the spinal cord to themuscles
Dorsal root (sensory)
Carry impulses from sensory receptors to thebody of the spinal cord
Then to brain for interpretation
Initiate a reflex response
Dermatome distribution
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Cranial Nerves
12 pairs
emerge from theundersurface of the brain.
Cranial nerve conductsimpulses (motor andsensory information)between the brain andvarious structures of thehead, neck, thoracic cavityand abdominal cavity.
IOlfactory nerve
IIOptic nerve
IIIOculomotor nerve
IVTrochlear nerve
VTrigeminal nerve
VIAbducens nerve
VIIFacial nerve VIIIAcoustic/Vestibulococ
hlear
IXGlossopharyngeal
nerve
XVagus nerve XIAccessory nerve
XIIHypoglossal nerve
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Autonomic Nervous System
Contains motor neurons that regulate
visceral organs & innervate ( supply
nerves to ) smooth & cardiac muscles& the glands
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TWO PARTS OF ANS
1. sympathetic nervous system
Controls the fight or flight response
2. parasympathetic nervous systrem
Maintains the baseline of the body functions
Resposible for the rest & digest response
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the NEURON or NERVE CELL is the nervous systems
fundamental unitthis highly specialized conductor cell receives and
transmits electrochemical nerve impulses
delicate, threadlike nerve fibers called
AXONS & DENDRITES extend from thecell body & transmit signals
Axons carry impulses away from the
cell body;dendrites carry impulses to the
cell body
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Each neuron communicates with each
other to a specific target tissue through
neurotransmitters
These neurotransmitters are produced
& stored in the synaptic vesicles;theyenable conduction of impulses across the
synaptic cleft
The action of neurotransmitters is to
potentiate, terminate or modulate a
specific action & can either excite orinhibit the target cells activity.
MAJOR NEUROTRANSMITTERS:
1. Acetycholine
2. Serotonin
3. Dopamine4. Norepinephrine
5. Gamma-aminobutyric acid (GABA)
6. Enkephalin,endorphin
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II. NEUROLOGICAL ASSESSMENTS
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NEUROLOGICAL ASSESSMENT
I. Mental Status: Reveals cerebral function (intellectual and
affective) Major areas of assessment:
a. Languageb. Orientationc. Memory d. Attention span
e. Calculation
Level of consciousness
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NEUROLOGICAL ASSESSMENT
A. Language
Aphasia
inability to express oneself by speech,
writing or comprehend spoken or writtenlanguage due to disease of cerebral cortex
Two Categories:1. Sensory or receptive aphasia
2. Motor or expressive aphasia
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NEUROLOGICAL ASSESSMENT
1. Sensory/receptive aphasia
- loss of ability to comprehend written orspoken words
Two types:a. Auditory aphasia unable to understand
symbolic content associated with sounds
b. Visual aphasia unable to understand printed
or written figures
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NEUROLOGICAL ASSESSMENT
2. Motor/ expressive aphasia
- loss of power to express oneself by writing,making signs or speaking
How to assess language deficits: Point to common objects and name them
Read some words and match printed and writtenwords with pictures
Respond to verbal/written commands
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NEUROLOGICAL ASSESSMENT
Speech Patterns:
- pace, clarity, spontaneity
Abnormalities:
a. Perseveration
- repeating the same response as differentquestions are asked
b. Paraphasia- speech appropriately expressed but containsincorrect words
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NEUROLOGICAL ASSESSMENT
B. Orientation 3 spheres
C. Memory
- Listen for lapses of memory
- If problems are present:
Three categories of memory:
1. Immediate recall
N: can repeat series of 5
8 digits in sequenceand 4 6 digits in reverse order
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NEUROLOGICAL ASSESSMENT
C. Memory
2. Recent memory
- Ask to recall the events of the day- Recall information given early in the
interview
- Provide 3 facts to recall (color, object,address), then ask later
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NEUROLOGICAL ASSESSMENT
C. Memory
3. Remote memory
- Previous illness or surgery (years ago), birthday,
anniversaryD. Attention Span
- Tests the ability to concentrate
(alphabet, count backward from 100)
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NEUROLOGICAL ASSESSMENT
E. Calculation
- Serial seven or serial three test
N: can complete serial seven in 90 secondswith 3 or less errors
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Mental status
Utilize the Glasgow Coma Scale
An easy method of describing mental status
and abnormality detection
Tests 3 areas- eye opening, verbal response
and motor response
Scores are evaluated- range from 3-15
NoZERO score
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Glascow Coma Scale
Score BEST response
in each category
Highest score = 15
(normal)
Lowest score = 3
(deep coma)
Eye OpeningSpontaneous
To Voice
To Pain
None
Best VerbalOriented
Confused
Inappropriate Words
Incomprehensible Sounds
None
Best MotorObeys Commands
Localizes Pain
Withdraws to Pain
Flexion to Pain (decorticate)
Extension to Pain (decerebrate)None
4
3
2
1
5
4
3
2
1
65
4
32
1
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Altered Level of Consciousness (LOC)
Confusion
Delirium
Impaired ability to think clearly
Disturbed ability to perceive, respond to, and
remember current stimuli
Disorientation Functional in activities of daily living (ADLs)
Motor restlessness
Increased disorientation
Transient hallucinations
Delusions possible
Requires some assistance with ADLs
can result from destruction of the brain stem or its reticular formation of ascending
nerves, or from other structural, metabolic, or psychogenic disturbances.
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Altered Arousal/Level of Consciousness (LOC)
cont.
Obtundation
Stupor
Coma
Decreased alertness
Psychomotor retardation
Requires complete assistance with ADLs
Arousable but not alert
Severe disorientation
Little or no spontaneous activity
Unarousable
Unresponsive to external stimuli or internal needs
Determination commonly documented usingGlasgow Coma Scale score
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Altered Movement
Involves certain neurotransmitters (ex. dopamine)
Hyperkinesia- excessive movement
Hypokinesia- decreased movement
Marked byparesis- partial loss of motor function and
muscle power; commonly described as weakness;
can result from destruction of upper & lower motor
neurons
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Cranial Nerve Function
Assess cranial nerve function.
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CRANIAL NERVESCranial Nerves
I olfactory smell
II optic vision
III oculomotor Most eye movt, pupillary constriction, upper eyelid elevation
IV trochlear Down & in down movt
V trigeminal Chewing, corneal reflex, face & scalp sensations
VI abducent Lateral eye movement
VII facial Expressions in forehead
VIII acoustic Hearing & balance
IX glossopharynge
al
Swallowing, salivating, taste
X vagus Swallowing, gag reflex, talking, sensations of the throat, larynx & abdl viscera,activities of thoracic & abdl viscera, e.g. HR, & peristalsis
XI accessosy Shoulder movt, head rotation
XII hypoglossal Tongue movt
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Cranial Nerve Function: Cranial Nerve
1- Olfactory
Check first for the patency of the nose
Instruct to close the eyes
Occlude one nostrils at a time
Hold familiar substance and asks for the
identification
Repeat with the other nostrils
PROBLEM- ANOSMIA- loss of smell
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Cranial Nerve Function: Cranial Nerve
2- Optic
Check the visual acuity with the use of the
Snellen chart
Check for visual field by confrontation test
Check for pupillary reflex- direct and
consensual
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Snellen chart
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Cranial Nerve Function: Cranial Nerve
3, 4 and 6
Assess simultaneously the movement of the
extra-ocular muscles
Deviations:
Opthalmoplegia- inability to move the eye in a
direction
Diplopia- complaint of double vision
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C i l N F i C i l N
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Cranial Nerve Function: Cranial Nerve
5 -trigeminal
Sensory portion- assess for sensation of the
facial skin
Motor portion- assess the muscles of
mastication
Assess corneal reflex
C i l N F i C i l N
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Cranial Nerve Function: Cranial Nerve
7 -facial
Sensory portion- prepare salt, sugar, and
vinegar. Place each substance in the anterior
two thirds of the tongue, rinsing the mouth
with water
Motor portion- ask the client to make facial
expressions, ask to forcefully close the eyelids
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Cranial Nerve Function: Cranial Nerve 8- vestibulo-
auditory
Test patients hearing acuity
Observe for nystagmus and disturbed balance
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Cranial Nerve Function: Cranial Nerve 9-
glossopharyngeal
Together with Cranial nerve 10vagus
Assess for gag reflex
Watch the soft palate rising after instructing
the client to say AH
The posterior one-third of the tongue is
supplied by the glossopharyngeal nerve
C i l N F ti C i l N
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Cranial Nerve Function: Cranial Nerve
11- accessory
Press down the patients shoulder while he
attempts to shrug against resistance
C i l N F ti C i l N
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Cranial Nerve Function: Cranial Nerve
12- hypoglossal
Ask patient to protrude the tongue and note
for symmetry
3. Motor System Function
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3. Motor System FunctionAssess muscle size (inspect and palpate) tone, and strength;
assess symmetry differences between right and left side; balance
and coordination.
Altered Muscle Tone
Hypotonia- severely reduced degree oftension or resistance to movement in a muscle
Hypertonia- marked increase in a muscle
tension and decreased ability of a muscle tostretch
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MUSCLE GRADING
5- Normal-Complete range of motion against gravity with full resistance
4- Good
-Complete range of motion against gravity with some resistance
3- Fair
-Complete range of motion against gravity2- Poor
-Complete range of motion against gravity eliminated
1- Trace
-Evidence of slight contractility. No joint motion.
0- ZeroNo evidence of contractility
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4.Sensory FunctionTest for:
superficial tactile sensation superficialand deep pressure pain
thermal sensitivity
sensitivity to vibration point localization.
Reflexes
Evaluate deep and superficial reflexes(biceps, triceps, patellar, ankle reflexes)and abnormal reflexes (Babinskis reflex).
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4.Sensory Function
Primary Sensory Functions Always with the persons eyes closed
Vision, hearing, smell, taste and facial sensations
Part to be Assess Hands
Lower arms
Abdomen
Feet
Lower legs
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4.Sensory Function
Primary Sensory Functions Superficial touch
Use a cotton wisp
Have the person point to the area touched
Superficial pain
Sharp and dull sensations
Allow 2 seconds between each stimulus
Temperature and deep pressure ONLY TESTED when superficial pain sensation is not
intact
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4.Sensory Function
Primary Sensory Functions
Vibration
Place stem of tuning fork against bony prominences
Begin distally
Sites
Sternum
Finger wrist elbow - shoulder
Toes ankle shin
Position of joints (great toes, one finger on each hand) Up
Down
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4.Sensory Function
Cortical Sensory Functions
Always with the persons eyes closed
Stereognosis
Ability to identify a familiar object by touch andmanipulation
Tactile agnosia: inability to recognize objects
Graphesthesia
With a blunt pen, draw a letter or number on the palm
Should be readily recognized
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4.Sensory Function
Cortical Sensory Functions
Point location
Touch an area of the body and ask the person to point
to where you have touched This is being tested the same time as superficial touch
Extinction phenomenon
Simultaneously touch one or both sides of the body
Ask the person to point to where you have touched
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4.Sensory Function
Cortical Sensory Functions Two-point discrimination
Use two pointed objects, alternate touching skin withone or two points
Find the distance at which the person can no longerdiscriminate 2 points
Fingertips 2 - 8 mm
Toes 3 - 8 mm
Palms 8-12 mm Forearms 40 mm
Upper arms and thighs 75 mm
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Proprioception/Cerebellar Function
Proprioception
The sensation of position and muscular activity
originating from within the body which provides
awareness of posture, movement, and changes inequilibrium
Test
Coordination and Fine Motor Skills
Balance
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Proprioception/Cerebellar Function
Coordination and Fine Motor Skills Rapid rhythmic alternating movements
Have seated person alternately pronate and supinatehands, patting knees, and gradually increasing speed
OR Have person touch thumb to each finger on the same
hand sequentially from index to little finger and back,gradually increasing speed
person should be able to do these movementssmoothly, maintaining rhythm, with increasing speed
Observe for slow, stiff, non-rhythmic, or jerkymovements
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Proprioception/Cerebellar Function
Coordination and Fine Motor Skills
Accuracy of movement
Finger-to-finger test with persons eyes open Movements should be rapid, smooth, and accurate
Consistent past pointing may indicate cerebellar impairment
Finger to nose test with persons eyes closed
Movement should be smooth, accurate, and rapid
Heel-to-shin with person supine, sitting, or standing
Should move heel from knee up and down the shin in a
straight line, without irregular deviations to the side
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Proprioception/Cerebellar Function
Coordination and Fine Motor Skills
Balance: Equilibrium
Romberg test Have person stand with arms at side and feet together
Have person perform initially with eyes open and then with
eyes closed
Stand close to prevent falls
person should maintain position with eyes open or closed for
20 seconds with only minimal swaying
If the Romberg is positive (i.e. there is significant swaying or
the person has to take a step to maintain/regain balance) DO
NOT DO OTHER TESTS OF BALANCE
http://www.webster.edu/~davittdc/ear/romberg/romberg.mov -
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III.DIAGNOSTIC TEST
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DIAGNOSTIC TESTS
EEG - Graphic record of the electrical activity generated in the brain. EEG is a useful test for diagnosing and evaluating seizure
disorders, coma, or organic brain syndrome.
Nursing implication: Withhold medications that may interfere with the results-
anticonvulsants, sedatives and stimulants Wash hair thoroughly before procedure
Explain the procedure, assure the client he/she will not receiveelectrical shock.
The nurse needs to check doctors order regarding the administration
of antiseizure medication prior to testing. Withhold tranquillizer and stimulants for 24 to 48 hours.
Inform the client that the standard EEG takes 45 to 60 minutes and 12hours for sleep EEG.
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DIAGNOSTIC TESTS
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DIAGNOSTIC TESTS
CT scanVisualize sections of the spinal cord as well as intracranial contents
The injection of a water-soluble iodinated contrast into thesubarachnoid space through lumbar puncture helps
noninvasive and painless
has a high degree of sensitivity for detecting lesions.Use of xray beams cross section
Use : to identify intracranial tumor, hemorrhage, cerebral atrophy,calcification, edema, infarction, congenital abnormality.
With radiation risk If contrast medium will be used- ensure consent, assess for
allergies to dyes and iodine or seafood, flushing and metallictaste are expected as the dye is injected
DIAGNOSTIC TESTS
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MRI
Uses magnetic waves
Patients with pacemakers, orthopedic
metal prosthesis and implanted metal
devices cannot undergo this procedure
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DIAGNOSTIC TESTS
Cerebral arteriographyIs an x-ray study of the cerebral circulation with a contrastagent injected into a selected artery (femoral)
Visualize aneurysm
Nursing considerationNote allergies to dyes, iodine and seafood
Ensure consentKeep patient at rest after procedure
Maintain pressure dressing or sandbag overpunctured site
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Lumbar Puncture
is a procedure to collect cerebrospinal fluid tocheck for the presence of disease or injury.
A spinal needle is inserted, usually between the3rd and 4th lumbar vertebrae in the lower spine.Once the needle is properly positioned in the
subarachnoid space (the space between the spinalcord and its covering, the meninges), pressures canbe measured and fluid can be collected for testing.
DIAGNOSTIC TESTS
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DIAGNOSTIC TESTS
Lumbar puncture
Nursing considerations
Ensure consent, determine ability to lie stillContraindicated in patients with increased
ICP
Keep flat on bed after procedureIncrease fluid intake after procedure
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Tapos na PO