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    I. NEUROANATOMY

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    Anatomy and Physiology

    Gross anatomy

    The nervous system is divided into the central

    and peripheral nervous system

    The Central nervous system consists of the

    BRAIN and the Spinal Cord

    The peripheral nervous system consists of theSpinal nerves and the cranial nerves

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    BRAIN

    The Brain is divided into 3 major areas:

    1. Cerebrum

    2. Brain Stem3. Cerebellum

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    BRAIN- 1. Cerebrum

    The largest part of the brain. Composed of:

    2 hemispheres- the right and left, and the basal

    ganglia.

    The hemisphere is connected by corpus callosum, aband of fibers.

    Each hemisphere is divided into 4 lobes.

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    The 4 Lobes of the CEREBRUM

    1. Frontal Lobe Largest lobe

    location: frontof the skull.

    contains theprimary motor cortexand responsible

    for functions related to motor activity.

    The left frontal lobe containsBrocas area(controlthe ability to produce spoken words)

    The frontal lobecontrols higher intellectualfunction, awareness of self, and autonomic

    responses related to emotions.

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    2. Parietal

    Sensory lobe

    location: near the crown of the head.Contains theprimary sensory cortex.

    One of its major function is to process sensory inputsuch asposition sense, touch, shape, and consistency

    of objects.3. TemporalLocation: around the temples.

    Contains theprimary auditory cortex.

    Wernickes area is located on left temporal lobe. Contains the interpretative area where auditory, visual and

    somatic input are integrated into thought and memory

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    Lobes-cont.

    4. Occipital

    Location: lower back of the head

    Contains theprimary visual cortex

    Function: responsible for visual

    interpretation.

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    THE 4 LOBES

    Frontal- motor /controlshigher intellectualfunction, awareness ofself, and autonomicresponses related toemotions.

    Parietal- sensory

    Temporal-auditory(Wernickes); Containsthe interpretative areawhere auditory, visualand somatic input areintegrated into thoughtand memory

    Occipital-visual

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    Structure of the Brain

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    BRAIN-2. Brain Stem Consist of the midbrain, pons, and medulla oblongata.

    Midbrain

    -connects the pons and the cerebellum with the cerebralhemisphere, it contains sensory and motor pathways

    -center for auditory and visual reflexes

    Pons-connects the two halves of the cerebrum

    - involved in the integration of movements in the right and leftsides of the body, and the transmission of motor informationfrom the higher brain areas and the spinal cord to the

    cerebellum.medulla oblongata

    - involved in the respiration, circulation, gastrointestinalfunctioning, coughing, sneezing, and swallowing.

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    BRAIN-3. Cerebellum

    Location: base of the brain.

    Responsible for coordination, balance and

    posture.

    Damage to the cerebellum can resultinataxia, a

    condition characterized by drunken-like

    movements, severe tremors, and loss of

    balance.

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    Structures Protecting the Brain

    The brain is contained in the rigid skull, whichprotects it from injury.

    The meninges(fibrous connective tissuesthat cover the brain and the spinal cord)

    provide protection, support and nourishmentto the brain and the spinal cord.

    Layers of the meninges:

    1.dura mater

    2.arachnoid

    3.pia mater.

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    CSF

    CSF- provide a cushion, provide nutrition,maintain normal ICP, remove metabolic waste.

    Composition colorless, odorless fluid containing

    glucose, electrolytes, oxygen, water, small amountof carbon monoxide and few leukocytes.

    Produced in the choroid plexus of the ventricles.

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    BLOOD SUPPLY TO THE CNS

    1/3 of the cardiac output

    From 2 vertebral artery and one internal

    carotid arteries

    Circle of willis

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    Spinal Cord

    Approximately 45 cm long (18 inches) long.

    Acts as apassageway for condition of

    sensory information from the periphery

    of the body to the brain (via afferent

    nerve fibers).

    Serve as the connection between the brain and

    the periphery.Mediates the reflexes.

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    Spinal Nerves Spinal nerves

    31 pairs 8 cervical, 12 thoracic, 5 lumbar

    5 sacral, 1 coccygeal

    Two roots

    Ventral root (motor)

    Carry impulses from the spinal cord to themuscles

    Dorsal root (sensory)

    Carry impulses from sensory receptors to thebody of the spinal cord

    Then to brain for interpretation

    Initiate a reflex response

    Dermatome distribution

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    Cranial Nerves

    12 pairs

    emerge from theundersurface of the brain.

    Cranial nerve conductsimpulses (motor andsensory information)between the brain andvarious structures of thehead, neck, thoracic cavityand abdominal cavity.

    IOlfactory nerve

    IIOptic nerve

    IIIOculomotor nerve

    IVTrochlear nerve

    VTrigeminal nerve

    VIAbducens nerve

    VIIFacial nerve VIIIAcoustic/Vestibulococ

    hlear

    IXGlossopharyngeal

    nerve

    XVagus nerve XIAccessory nerve

    XIIHypoglossal nerve

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    Autonomic Nervous System

    Contains motor neurons that regulate

    visceral organs & innervate ( supply

    nerves to ) smooth & cardiac muscles& the glands

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    TWO PARTS OF ANS

    1. sympathetic nervous system

    Controls the fight or flight response

    2. parasympathetic nervous systrem

    Maintains the baseline of the body functions

    Resposible for the rest & digest response

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    the NEURON or NERVE CELL is the nervous systems

    fundamental unitthis highly specialized conductor cell receives and

    transmits electrochemical nerve impulses

    delicate, threadlike nerve fibers called

    AXONS & DENDRITES extend from thecell body & transmit signals

    Axons carry impulses away from the

    cell body;dendrites carry impulses to the

    cell body

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    Each neuron communicates with each

    other to a specific target tissue through

    neurotransmitters

    These neurotransmitters are produced

    & stored in the synaptic vesicles;theyenable conduction of impulses across the

    synaptic cleft

    The action of neurotransmitters is to

    potentiate, terminate or modulate a

    specific action & can either excite orinhibit the target cells activity.

    MAJOR NEUROTRANSMITTERS:

    1. Acetycholine

    2. Serotonin

    3. Dopamine4. Norepinephrine

    5. Gamma-aminobutyric acid (GABA)

    6. Enkephalin,endorphin

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    II. NEUROLOGICAL ASSESSMENTS

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    NEUROLOGICAL ASSESSMENT

    I. Mental Status: Reveals cerebral function (intellectual and

    affective) Major areas of assessment:

    a. Languageb. Orientationc. Memory d. Attention span

    e. Calculation

    Level of consciousness

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    NEUROLOGICAL ASSESSMENT

    A. Language

    Aphasia

    inability to express oneself by speech,

    writing or comprehend spoken or writtenlanguage due to disease of cerebral cortex

    Two Categories:1. Sensory or receptive aphasia

    2. Motor or expressive aphasia

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    NEUROLOGICAL ASSESSMENT

    1. Sensory/receptive aphasia

    - loss of ability to comprehend written orspoken words

    Two types:a. Auditory aphasia unable to understand

    symbolic content associated with sounds

    b. Visual aphasia unable to understand printed

    or written figures

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    NEUROLOGICAL ASSESSMENT

    2. Motor/ expressive aphasia

    - loss of power to express oneself by writing,making signs or speaking

    How to assess language deficits: Point to common objects and name them

    Read some words and match printed and writtenwords with pictures

    Respond to verbal/written commands

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    NEUROLOGICAL ASSESSMENT

    Speech Patterns:

    - pace, clarity, spontaneity

    Abnormalities:

    a. Perseveration

    - repeating the same response as differentquestions are asked

    b. Paraphasia- speech appropriately expressed but containsincorrect words

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    NEUROLOGICAL ASSESSMENT

    B. Orientation 3 spheres

    C. Memory

    - Listen for lapses of memory

    - If problems are present:

    Three categories of memory:

    1. Immediate recall

    N: can repeat series of 5

    8 digits in sequenceand 4 6 digits in reverse order

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    NEUROLOGICAL ASSESSMENT

    C. Memory

    2. Recent memory

    - Ask to recall the events of the day- Recall information given early in the

    interview

    - Provide 3 facts to recall (color, object,address), then ask later

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    NEUROLOGICAL ASSESSMENT

    C. Memory

    3. Remote memory

    - Previous illness or surgery (years ago), birthday,

    anniversaryD. Attention Span

    - Tests the ability to concentrate

    (alphabet, count backward from 100)

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    NEUROLOGICAL ASSESSMENT

    E. Calculation

    - Serial seven or serial three test

    N: can complete serial seven in 90 secondswith 3 or less errors

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    Mental status

    Utilize the Glasgow Coma Scale

    An easy method of describing mental status

    and abnormality detection

    Tests 3 areas- eye opening, verbal response

    and motor response

    Scores are evaluated- range from 3-15

    NoZERO score

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    Glascow Coma Scale

    Score BEST response

    in each category

    Highest score = 15

    (normal)

    Lowest score = 3

    (deep coma)

    Eye OpeningSpontaneous

    To Voice

    To Pain

    None

    Best VerbalOriented

    Confused

    Inappropriate Words

    Incomprehensible Sounds

    None

    Best MotorObeys Commands

    Localizes Pain

    Withdraws to Pain

    Flexion to Pain (decorticate)

    Extension to Pain (decerebrate)None

    4

    3

    2

    1

    5

    4

    3

    2

    1

    65

    4

    32

    1

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    Altered Level of Consciousness (LOC)

    Confusion

    Delirium

    Impaired ability to think clearly

    Disturbed ability to perceive, respond to, and

    remember current stimuli

    Disorientation Functional in activities of daily living (ADLs)

    Motor restlessness

    Increased disorientation

    Transient hallucinations

    Delusions possible

    Requires some assistance with ADLs

    can result from destruction of the brain stem or its reticular formation of ascending

    nerves, or from other structural, metabolic, or psychogenic disturbances.

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    Altered Arousal/Level of Consciousness (LOC)

    cont.

    Obtundation

    Stupor

    Coma

    Decreased alertness

    Psychomotor retardation

    Requires complete assistance with ADLs

    Arousable but not alert

    Severe disorientation

    Little or no spontaneous activity

    Unarousable

    Unresponsive to external stimuli or internal needs

    Determination commonly documented usingGlasgow Coma Scale score

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    Altered Movement

    Involves certain neurotransmitters (ex. dopamine)

    Hyperkinesia- excessive movement

    Hypokinesia- decreased movement

    Marked byparesis- partial loss of motor function and

    muscle power; commonly described as weakness;

    can result from destruction of upper & lower motor

    neurons

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    Cranial Nerve Function

    Assess cranial nerve function.

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    CRANIAL NERVESCranial Nerves

    I olfactory smell

    II optic vision

    III oculomotor Most eye movt, pupillary constriction, upper eyelid elevation

    IV trochlear Down & in down movt

    V trigeminal Chewing, corneal reflex, face & scalp sensations

    VI abducent Lateral eye movement

    VII facial Expressions in forehead

    VIII acoustic Hearing & balance

    IX glossopharynge

    al

    Swallowing, salivating, taste

    X vagus Swallowing, gag reflex, talking, sensations of the throat, larynx & abdl viscera,activities of thoracic & abdl viscera, e.g. HR, & peristalsis

    XI accessosy Shoulder movt, head rotation

    XII hypoglossal Tongue movt

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    Cranial Nerve Function: Cranial Nerve

    1- Olfactory

    Check first for the patency of the nose

    Instruct to close the eyes

    Occlude one nostrils at a time

    Hold familiar substance and asks for the

    identification

    Repeat with the other nostrils

    PROBLEM- ANOSMIA- loss of smell

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    Cranial Nerve Function: Cranial Nerve

    2- Optic

    Check the visual acuity with the use of the

    Snellen chart

    Check for visual field by confrontation test

    Check for pupillary reflex- direct and

    consensual

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    Snellen chart

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    Cranial Nerve Function: Cranial Nerve

    3, 4 and 6

    Assess simultaneously the movement of the

    extra-ocular muscles

    Deviations:

    Opthalmoplegia- inability to move the eye in a

    direction

    Diplopia- complaint of double vision

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    C i l N F i C i l N

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    Cranial Nerve Function: Cranial Nerve

    5 -trigeminal

    Sensory portion- assess for sensation of the

    facial skin

    Motor portion- assess the muscles of

    mastication

    Assess corneal reflex

    C i l N F i C i l N

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    Cranial Nerve Function: Cranial Nerve

    7 -facial

    Sensory portion- prepare salt, sugar, and

    vinegar. Place each substance in the anterior

    two thirds of the tongue, rinsing the mouth

    with water

    Motor portion- ask the client to make facial

    expressions, ask to forcefully close the eyelids

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    Cranial Nerve Function: Cranial Nerve 8- vestibulo-

    auditory

    Test patients hearing acuity

    Observe for nystagmus and disturbed balance

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    Cranial Nerve Function: Cranial Nerve 9-

    glossopharyngeal

    Together with Cranial nerve 10vagus

    Assess for gag reflex

    Watch the soft palate rising after instructing

    the client to say AH

    The posterior one-third of the tongue is

    supplied by the glossopharyngeal nerve

    C i l N F ti C i l N

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    Cranial Nerve Function: Cranial Nerve

    11- accessory

    Press down the patients shoulder while he

    attempts to shrug against resistance

    C i l N F ti C i l N

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    Cranial Nerve Function: Cranial Nerve

    12- hypoglossal

    Ask patient to protrude the tongue and note

    for symmetry

    3. Motor System Function

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    3. Motor System FunctionAssess muscle size (inspect and palpate) tone, and strength;

    assess symmetry differences between right and left side; balance

    and coordination.

    Altered Muscle Tone

    Hypotonia- severely reduced degree oftension or resistance to movement in a muscle

    Hypertonia- marked increase in a muscle

    tension and decreased ability of a muscle tostretch

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    MUSCLE GRADING

    5- Normal-Complete range of motion against gravity with full resistance

    4- Good

    -Complete range of motion against gravity with some resistance

    3- Fair

    -Complete range of motion against gravity2- Poor

    -Complete range of motion against gravity eliminated

    1- Trace

    -Evidence of slight contractility. No joint motion.

    0- ZeroNo evidence of contractility

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    4.Sensory FunctionTest for:

    superficial tactile sensation superficialand deep pressure pain

    thermal sensitivity

    sensitivity to vibration point localization.

    Reflexes

    Evaluate deep and superficial reflexes(biceps, triceps, patellar, ankle reflexes)and abnormal reflexes (Babinskis reflex).

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    4.Sensory Function

    Primary Sensory Functions Always with the persons eyes closed

    Vision, hearing, smell, taste and facial sensations

    Part to be Assess Hands

    Lower arms

    Abdomen

    Feet

    Lower legs

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    4.Sensory Function

    Primary Sensory Functions Superficial touch

    Use a cotton wisp

    Have the person point to the area touched

    Superficial pain

    Sharp and dull sensations

    Allow 2 seconds between each stimulus

    Temperature and deep pressure ONLY TESTED when superficial pain sensation is not

    intact

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    4.Sensory Function

    Primary Sensory Functions

    Vibration

    Place stem of tuning fork against bony prominences

    Begin distally

    Sites

    Sternum

    Finger wrist elbow - shoulder

    Toes ankle shin

    Position of joints (great toes, one finger on each hand) Up

    Down

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    4.Sensory Function

    Cortical Sensory Functions

    Always with the persons eyes closed

    Stereognosis

    Ability to identify a familiar object by touch andmanipulation

    Tactile agnosia: inability to recognize objects

    Graphesthesia

    With a blunt pen, draw a letter or number on the palm

    Should be readily recognized

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    4.Sensory Function

    Cortical Sensory Functions

    Point location

    Touch an area of the body and ask the person to point

    to where you have touched This is being tested the same time as superficial touch

    Extinction phenomenon

    Simultaneously touch one or both sides of the body

    Ask the person to point to where you have touched

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    4.Sensory Function

    Cortical Sensory Functions Two-point discrimination

    Use two pointed objects, alternate touching skin withone or two points

    Find the distance at which the person can no longerdiscriminate 2 points

    Fingertips 2 - 8 mm

    Toes 3 - 8 mm

    Palms 8-12 mm Forearms 40 mm

    Upper arms and thighs 75 mm

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    Proprioception/Cerebellar Function

    Proprioception

    The sensation of position and muscular activity

    originating from within the body which provides

    awareness of posture, movement, and changes inequilibrium

    Test

    Coordination and Fine Motor Skills

    Balance

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    Proprioception/Cerebellar Function

    Coordination and Fine Motor Skills Rapid rhythmic alternating movements

    Have seated person alternately pronate and supinatehands, patting knees, and gradually increasing speed

    OR Have person touch thumb to each finger on the same

    hand sequentially from index to little finger and back,gradually increasing speed

    person should be able to do these movementssmoothly, maintaining rhythm, with increasing speed

    Observe for slow, stiff, non-rhythmic, or jerkymovements

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    Proprioception/Cerebellar Function

    Coordination and Fine Motor Skills

    Accuracy of movement

    Finger-to-finger test with persons eyes open Movements should be rapid, smooth, and accurate

    Consistent past pointing may indicate cerebellar impairment

    Finger to nose test with persons eyes closed

    Movement should be smooth, accurate, and rapid

    Heel-to-shin with person supine, sitting, or standing

    Should move heel from knee up and down the shin in a

    straight line, without irregular deviations to the side

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    Proprioception/Cerebellar Function

    Coordination and Fine Motor Skills

    Balance: Equilibrium

    Romberg test Have person stand with arms at side and feet together

    Have person perform initially with eyes open and then with

    eyes closed

    Stand close to prevent falls

    person should maintain position with eyes open or closed for

    20 seconds with only minimal swaying

    If the Romberg is positive (i.e. there is significant swaying or

    the person has to take a step to maintain/regain balance) DO

    NOT DO OTHER TESTS OF BALANCE

    http://www.webster.edu/~davittdc/ear/romberg/romberg.mov
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    III.DIAGNOSTIC TEST

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    DIAGNOSTIC TESTS

    EEG - Graphic record of the electrical activity generated in the brain. EEG is a useful test for diagnosing and evaluating seizure

    disorders, coma, or organic brain syndrome.

    Nursing implication: Withhold medications that may interfere with the results-

    anticonvulsants, sedatives and stimulants Wash hair thoroughly before procedure

    Explain the procedure, assure the client he/she will not receiveelectrical shock.

    The nurse needs to check doctors order regarding the administration

    of antiseizure medication prior to testing. Withhold tranquillizer and stimulants for 24 to 48 hours.

    Inform the client that the standard EEG takes 45 to 60 minutes and 12hours for sleep EEG.

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    DIAGNOSTIC TESTS

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    DIAGNOSTIC TESTS

    CT scanVisualize sections of the spinal cord as well as intracranial contents

    The injection of a water-soluble iodinated contrast into thesubarachnoid space through lumbar puncture helps

    noninvasive and painless

    has a high degree of sensitivity for detecting lesions.Use of xray beams cross section

    Use : to identify intracranial tumor, hemorrhage, cerebral atrophy,calcification, edema, infarction, congenital abnormality.

    With radiation risk If contrast medium will be used- ensure consent, assess for

    allergies to dyes and iodine or seafood, flushing and metallictaste are expected as the dye is injected

    DIAGNOSTIC TESTS

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    MRI

    Uses magnetic waves

    Patients with pacemakers, orthopedic

    metal prosthesis and implanted metal

    devices cannot undergo this procedure

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    DIAGNOSTIC TESTS

    Cerebral arteriographyIs an x-ray study of the cerebral circulation with a contrastagent injected into a selected artery (femoral)

    Visualize aneurysm

    Nursing considerationNote allergies to dyes, iodine and seafood

    Ensure consentKeep patient at rest after procedure

    Maintain pressure dressing or sandbag overpunctured site

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    Lumbar Puncture

    is a procedure to collect cerebrospinal fluid tocheck for the presence of disease or injury.

    A spinal needle is inserted, usually between the3rd and 4th lumbar vertebrae in the lower spine.Once the needle is properly positioned in the

    subarachnoid space (the space between the spinalcord and its covering, the meninges), pressures canbe measured and fluid can be collected for testing.

    DIAGNOSTIC TESTS

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    DIAGNOSTIC TESTS

    Lumbar puncture

    Nursing considerations

    Ensure consent, determine ability to lie stillContraindicated in patients with increased

    ICP

    Keep flat on bed after procedureIncrease fluid intake after procedure

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    Tapos na PO