Breast Pathology

Breast pathologyBreast pathology

The normal microscopic appearance of female breast tissue is shown here. There is a larger duct to the right and lobules to the left. A collagenous stroma extends between the structures. A variable amount of adipose tissue can be admixed with these elements.

Here is the microscopic appearance of a fibroadenoma. To the right is compressed breast connective tissue forming a "capsule" to this mass. The neoplasm itself is composed of a fibroblastic stroma in which are located

elongated compressed ducts lined by benign appearing epithelium.

fibrocystic changes in breast

Blue dome cyst

Apocrine change

epithelial hyperplasia

intraductal papilloma

Paget's disease

Breast CancerBreast Cancer

Classification Breast CA

Lobular CIS (low)

Lobular CIS (high)

intraductal carcinoma

The cells in the center of the ducts with comedocarcinoma are often necrotic and calcify, as shown here. This central necrosis leads to the gross characteristic of extrusion of cheesy material from the ducts with pressure (comedone-like).

Both intraductal and infiltrating ductal carcinoma

infiltrating ductal carcinoma

colloid, or mucinous carcinoma

Invasive lobular carcinoma

Invasive lobular carcinoma

Medullary carcinomas