breast & its diseases
TRANSCRIPT
Breast Problems
Breast Development
• Contains mainly fat tissue, connective tissue and glands
• 15-25 ducts• Breast tissue extends
into axilla (“tail”)• Smallest, day 4-7
Quadrants
• Breast is divided into quadrants
• Upper-Outer quadrant has the greatest mass
• UOQ is the site of about half of all breast cancers
Supernumerary Breasts
• Relatively common• Found along “milk
line”• Most identified during
pregnancy/lactation• Most common in axilla• Not dangerous
Supernumerary Nipples
• More common than supernumerary breasts
• Found along milk line• May darken during
pregnancy• Not dangerous
Inverted Nipples
• Often will evert with stimulation
• Mostly a cosmetic issue
• Successful breastfeeding is usually possible.
Adolescent Breast Problems
• Assymetric growth is the rule rather than the exception.
• Mammary hypertrophy: Postpone surgical intervention until all growth has occurred
• Breast masses are ~100% benign and surgery or FNA is almost never warranted (disturbs breast architecture and may be disfiguring
Pregnancy Changes
• 1st TM: Tender breasts and nipples• 2nd TM: Non-tender breasts enlarge• 2nd-3rd TM: Steady darkening of nipples and
prominent Montgomery’s glands
Puerperal Mastitis• Rapid onset of red, hot,
swollen, tender breast• High fever• Prompt treatment
(Amox, Diclox, Erythromycin, Azithromycin
• Abscess needs drainage• Keep breast-feeding
Nipple Laceration
• Keep clean and dry.• Stop breastfeeding that side and allow to heal• Antibiotics usually not necessary
Cyclic Breast Pain
• Worst just before menses• Thick, tender, nodular breasts• Not dangerous but annoying• Rx: OCPs (cyclic or continuous)• Rx: Danazol (extreme cases)• Reduce caffeine? Vitamin E?
Non-Cyclic Breast Pain
• Often due to trauma (breast or chest wall)• May be due to muscle strain• May be due to increased levels of estrogen• Usually not due to cancer• Examine and refer if cause is not obvious.
Nipple Discharge• Normal nipple discharge is
clear, milky or green-tinged.
• If bloody, needs surgical evaluation
• If it stains the inside of the bra each day, that is galactorrhea and will need thyroid and pituitary evaluation.
Fat Necrosis• Tender, thickened, bruised area of breast• Follows trauma• Benign• Resolves spontaneously over weeks to months• Atypical cases should have FNA
Breast Cyst• Smooth, unilateral mass• Feels like a cyst• Infrequently associated
with malignancy• Aspirate• Watch for reforming of cyst• Recurring cysts are more
worrisome
Paget’s Disease• Crusty, flaking lesion• Gradual onset over
months or years• Associated with
underlying breast malignancy
• Diagnosis confirmed by needle biopsy
Breast Mass• Dominant mass• Unilateral• Persists through the
menstrual cycle• Usually biopsied
(FNA or excisional)• Can wait weeks but
not months
Fibroadenoma• Common• Benign• Solid, rubbery, non-tender• Round or oval• Rarely grow > 2-3 cm• FNA or excisional Bx• Observe in adolescents
Breast Cancer• 30% of all cancers in women• Treatment is successful in 3/4• Rare before age 25• Steadily increasing frequency with increasing
age• Affects 1/9 women reaching age 90.
Breast Cancer Risk Factors• Strong family history• Menopause after age 55• No term pregnancy prior to age 35• Most (80%) of breast cancer occurs in women not
at increased risk.