blood glucose management for games & interval exercise ......intense - 75% na therapy management...

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Blood Glucose Management for Games & Interval Exercise for People with Type 1 Diabetes Dr Othmar Moser Diabetes Research Group & A-STEM [email protected] https://www.researchgate.net/profile/Othmar_Moser

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  • Blood Glucose Management for

    Games & Interval Exercise for

    People with Type 1 Diabetes

    Dr Othmar Moser

    Diabetes Research Group & A-STEM

    [email protected]

    https://www.researchgate.net/profile/Othmar_Moser

  • Table of Content

    • Games & interval exercise – different or the same?

    • Safe for people with type 1 diabetes?

    • Therapy management around games & interval exercise

    • Expected glucose responses

    • New technology/insulin and games & interval exercise

  • Games & interval exercise – different or the same?

    Matthew et al., 2009

    Cipryan et al., 2017

    Gibala e al., 2012

    Games & interval exercise describe physical exercise that is

    characterised by brief, intermittent bursts of vigorous activity (O),

    interspersed by periods of rest or low-intensity exercise (O).

    Basketball Game Interval exercise

    Random orderStructured

  • Safe for people with type 1 diabetes?

    • Games and interval exercise can be associated with a

    higher risk of nocturnal hypoglycaemia than continuous

    aerobic exercise

    • No data exist on increased risk of cardiovascular events

    (e.g. myocardial infarction) during interval exercise in

    people with type 1 diabetes

    • Even in patients with coronary heart disease, an event rate

    of 1 nonfatal heart attack per 23182 hours of interval

    training it is reported

    Moser et al., 2015

    Riddell et al., 2017

    Rognmo et al., 2012

    YES!

  • 1Low = fast walking, jogging (easily talking)

    Moderate = fast jogging, moderate running (talking possible)

    Heavy = fast running (talking demanding)

    Intense = fast running (talking not possible)

    Therapy management around games &

    interval exercise

    Riddell et al., 2017

    Moser et al., 2017

    Moser et al., 2015

    Intensity 30 min exercise 60 min exercise

    Low1 - 25% for bolus

    insulin (60-90 min

    prior exercise)

    - 50%

    Moderate - 50% - 75%

    Heavy - 75% NA

    Intense - 75% NA

  • Therapy management around games &

    interval exercise

    Starting blood glucose below 5 mmol/L (

  • Expected glucose responses to games

    Game

    Continuous

    exercise

    - 5.3 ± 0.4 mmol/L

    - 1.1 ± 0.7 mmol/L

    45 min

    Campbell at al., 2014

  • Expected Glucose Responses to Interval

    Exercise (20 sec Sprints)

    Moser et al., 2015

    No difference in blood glucose

    decrease in comparison of continuous

    exercise and interval exercise in blood

    glucose response during exercise

    and during 24 hrs after exercise for

    different exercise intensities!

  • New Technology/Insulin for Games & Interval

    Exercise

    • Flash glucose monitoring

    • Continuous glucose monitoring

    • Basal-automatic artificial pancreas

    • Ultra-long acting insulins

    • Faster-short acting insulins

    Exercise

    studies

    INT/Games

    studies

  • Reality around Games & Interval Exercise…

  • … but doable?

  • Take Home Message

    • Games & interval exercise are safe for people with type 1

    diabetes

    • Therapy adaptation is mainly based on exercise intensity

    and duration

    • Adequate reaction to starting blood glucose levels are

    necessary

    • Blood glucose response to games & interval exercise may

    vary

  • Literature

    1. Lukas Cipryan, et al. Acute and Post-Exercise Physiological Responses to High-Intensity Interval Training in Endurance and

    Sprint Athletes. J Sports Sci Med. 2017 Jun;16(2):219-229.

    2. Dionne Matthew, Anne Delextrat. Heart rate, blood lactate concentration, and time–motion analysis of female basketball players

    during competition. Journal of Sports Sciences, June 2009; 27(8): 813–821.

    3. Martin Gibala, et al. Physiological adaptations to low-volume, high-intensity interval training in health and disease. J Physiol

    590.5 (2012) pp 1077–1084.

    4. Othmar Moser, et al. Effects of High-Intensity Interval Exercise versus Moderate Continuous Exercise on Glucose Homeostasis

    and Hormone Response in Patients with Type 1 Diabetes Mellitus Using Novel Ultra-Long-Acting Insulin. PLoS ONE 10(8):

    e0136489. doi:10.1371/journal.pone.0136489.

    5. Michael C Riddell, et al. Exercise management in type 1 diabetes: a consensus statement. Lancet Endocrinology. 2017

    http://dx.doi.org/10.1016/S2213-8587(17)30014-1.

    6. Rognmo Ø, et al. Cardiovascular risk of high- versus moderate-intensity aerobic exercise in coronary heart disease patients.

    Circulation. 2012. 126(12):1436-40.

    7. Othmar Moser, et al. Short-Acting Insulin Reduction Strategies for Continuous Cycle Ergometer Exercises in Patients with Type

    1 Diabetes Mellitus. Asian J Sports Med. 2017 March; 8(1):e42160.

    8. Campbell, et al. Simulated games activity vs continuous running exercise: A novel comparison of the glycemic and metabolic

    responses in T1DM patients. Scand J Med Sci Sports 2014: doi: 10.1111/sms.12192

  • Dankeschön!

    Othmar Moser

    E-mail: [email protected]

    Tel: +44 7757 062851

    Web: researchgate.net/profile/Othmar_Moser

    Twitter: @Othmar_moser