bioremediation of asbestos · 2018-04-03 · bioremediation of asbestos asbestos roof. asbestos ......
TRANSCRIPT
SanjayK.Mohanty,Ph.D.UniversityofPennsylvaniaApril04,2016
BIOREMEDIATIONOFASBESTOS
Asbestos roof
Asbestos
• Naturallyoccurringfibrousminerals
• Industrialuse:heat-andabrasion-resistantmaterials;roof,insulator;winefiltration…
AsbestosPile,Ambler,PA
http://www.boritcag.org/photo/index.html
Asbestos
• Exposuretoasbestoscancauseasbestosis,mesothelioma,andlungcancer.
• IntheUS,30peopledieeachdayduetoasbestos-relateddisease.
Whyisasbestostoxic?
Physicalstructure• Rigidity• LongfiberChemicalproperties• Ironenhancesasbestostoxicity
Histologicalexaminationofhumanlungtissuewithasbestosbodies.(Pascoloetal.2013ScientificReport)
Whyis(free)irontoxic?
Goal
Tolowerasbestosexposurepotentialtocommunitybytreatingtheasbestosfibersunderground.ü Decreasefiber
toxicityü Breakdownfiber
BestRemediationPlan:Capping
April2015
VegetativecoverGE-Pittsfield/HousatonicRiverSite
Canweremoveironandbreakdownasbestosundergroundusingplant(nativegrass)?
Mycorrhizal fungi
O
-O
O
O-
O
O-
O
-O
OH
O
O-
O O-
O
-O
N
N
N
HO
HO
OH
O
O
O
HN
NH
H2N
OO
O
-O
O
O-
Exudates
FeCa
Plantsneedfungitogetnutrientslockedinmineralsorrocks.
http://creating-a-new-earth.blogspot.com/2014_12_01_archive.html
“TheWorld'sLargestMiningOperationIsRunbyFungi”
http://blogs.scientificamerican.com/artful-amoeba/the-world-s-largest-mining-operation-is-run-by-fungi/
Wheredowetypicallyusefungi?
Materialsq AsbestosFiber(Chrysotile) q PlantandFungalExudates
Desferrioxamine B (DFO-B) siderophore
N
N
N
HO
HO
OH
O
O
O
HN
NH
H2N
OO
Chrysotileore(Globe,Arizona)
Plantandfungalexudatescanremoveironfromasbestosfibers
N
N
N
HO
HO
OH
O
O
O
HN
NH
H2N
OO
Mohanty et al.(2016 b) In Preparation!
A sustainable remediation design!
Ongoingwork
• Greatstart,butwehavealong-waytogo
• Phytoremediationusingnativegrass
• Possiblefieldexperimentatadifferentsite
Remediationofasbestos-contaminatedsite
Cap
Subsurface leakage
Asbestos fibers
Erosion
ABetterStrategy?
CurrentRemediationPlan
Reduction in toxicity and mobility of asbestos fibers
Plants
Acknowledgements
Prof. Jane Willenbring!Earth and Environmental Science!
U. of Pennsylvania!
Prof. Brenda Casper!Biology Department!U. of Pennsylvania!
Ashkan Salamatipour!(Pre-med Student)!U. of Pennsylvania!
Dr. Cedric Gonneau!Postdoctoral Scholar!U. of Pennsylvania!