bio111l-sec. i printed
TRANSCRIPT
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ANATOMICAL POSITION
– the subject stands erect
facing the observer, with
legs together and feet
slightly apart, arms at the
sides with palms facing
the front, and with the
thumbs away from the
body
Directional Terms
• Directional terms describe the locations of
structures in relation to other structures or
locations in the body.
• These terms often have a counterpart with
converse or opposite meaning.
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Directional Terms
• Superior – Towards the head or
upper part of astructure or the body;above (this term ismainly used in thetorso region)
• Inferior – Away from the head
or toward the lowerpart of a structure or
the body; below (thisterm is mainly used inthe torso region)
Directional Terms
• Anterior (ventral) – Towards the front of the
body, organ, or section ofthe body
– This term is only
used interchangeably inhumans
• Posterior (dorsal) – Towards the back of the
body, organ, or section ofthe body
– This term is only
used interchangeably inhumans
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Directional Terms
• Medial – Towards the
middle of the body,
organ, or section of
the body
• Lateral
– Towards the side
of the body, organ,
or section of the
body
Directional Terms
• Lateral
– Ipsilateral
• On the same
side of the body
– gallbladder and
ascending colon
– Contralateral
• Opposite sidesof the midline
– ascending and
descending
colon
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Directional Terms
• Proximal
– Closest to the point
of attachment
• the wrist is proximal to
the fingers
• Distal
– Away from the point
of attachment
• the fingers are distal to
the wrist
Directional Terms
• Deep (internal)
– Towards the internal
portion of the body
• organs are deep to the
skin
• Superficial (external)
– Away from the
internal portion of the
body• skin is superficial to the
organs
Skin
Organ
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Activity
• Use 3 directional terms to describe the location of thefollowing
• (Remember that directional terms are always relative to
something. Be sure to state that the structure is
superior to the … or proximal to the …)
– The right small finger
– The left shoulder blade
– The nose
– The right ear
– The liver
– The left knee
Planes• Medical professionals often refer to
sections of the body in terms of anatomical
planes (flat surfaces)
• These planes are imaginary lines – vertical
or horizontal – drawn through an upright
body
• The terms are used to describe a specific
body part
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Types of Planes
1) Sagittal plane – This vertical (up and
down) plane divides
the body, organ, or
section of the body
into right and left
sections
– Has 2 sub-types
a) Midsagittal
b) Parasagittal
Median or Midsagittal plane
• This vertical (up and
down) plane divides the
body, organ, or section
of the body into equal
right and left halves
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• Parasagittal plane
– This vertical (up and
down) plane divides
the body, organ, or
section of the body
into unequal right
and left parts
2) Frontal or Coronalplane
– This vertical (up and
down) plane divides
the body, organ, or
section of the body
into anterior and
posterior portions
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3) Transverse
(cross sectional
or Horizontal)
plane – This plane divides
the body, organ, or
section of the body
into superior and
inferior portions
Planes and Sections of the Brain
• Horizontal
Plane
• Frontal Plane
• Midsagittal
Plane
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Body Cavities• The spaces of the body containing the
internal organs (viscera).
• The two main cavities are;
i) Ventral Cavity (subdivided into the
thoracic and abdominopelvic cavities)
ii) Dorsal Cavity (subdivided into the cranial
and vertebral or spinal cavities)
• The ventral cavity is the larger cavitytowards the front of the body.
The ventral Body Cavity
– Subdivided into
a) thoracic cavity which is superior(above) to the diaphragm.
b) abdominopelvic cavity which isinferior (below) to the diaphragm.
These two sub-cavities are separatedby the diaphragm, a dome-
shaped muscle of respiration
– Each of these major subdivisionsof the ventral cavity can be furthersubdivided.
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Thoracic Body CavitiesDivided into 4
subcavities locatedabove the diaphragm;
• 2 Pleural cavities
- One containing the
right lung and the other
the left lung.
• 1 Superior mediastinum;
- space between the
two pleural cavities thatcontains organs.
• 1 Pericardial cavity;
- contains the heart.
Abdominopelvic Cavity
Divided into 2 subcavitieslocated below thediaphragm;
• Abdominal cavity
– this space contains theabdominal organs(stomach, intestine,spleen, liver, etc.
• Pelvic cavity
– space that contains theurinary bladder, somereproductive organs,and the rectum.
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Dorsal Body Cavity
is subdivided into;i) cranial cavity
- contains the brain
and its associated
membranes.
ii) vertebral or
spinal cavity
- contains the spinalcord and its
associated
membranes.
Abdominopelvic regions
• Right hypochondriac region
– This region is located laterally to
the Epigastric region (remember
your anatomical right)
• Right lumbar region
– This region is located laterally to
the umbilical region (remember
your anatomical right)
• Right iliac or inguinal region
– Is located laterally to the
hypogastric region
– (remember your anatomical
right)
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Abdominopelvic regions
• Epigastric region
– This region is located superior
to the umbilical region
• Umbilical
– This region is the centermost
region
• Hypogastric (pubic) region
– Is located inferiorly to theumbilical region
Abdominopelvic regions
• Left hypochondriac region – This region is located laterally to
the epigastric region (rememberyour anatomical left)
• Left lumber – This region is located laterally to
the umbilical region (rememberyour anatomical left)
• Left iliac or inguinal region – Is located laterally to the
hypogastric region
– (remember your anatomicalleft)
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Quadrants
• RUQ
– right upper quadrant
• RLQ
– right lower quadrant
• LUQ
– left upper quadrant
• LLQ
– left lower quadrant
Activity• Get a torso model
• Please use only wooden pointers with themodels NOT PENS!
• Name the regions and quadrants where thefollowing organs are found. – The liver
– The gall bladder
– The stomach
– The right kidney
– The spleen
– The large intestine
– The urinary bladder
– Vermiform appendix
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Membranes
• Body membranes are thin sheets of tissue that
line body cavities, and cover internal organs
within the cavities.
• 2 types;
a) Parietal membranes.
b) Visceral membranes
• Parietal membrane
– this serous
membrane lines the
cavity walls or can
line the outside wall
of an organ
• Visceral membrane
– this serous
membrane covers the
organs in the cavity
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Membranes of the Heart
• Parietal pericardium
– lines the pericardial
cavity (pericardial
sac)
• Visceral pericardium
or epicardium
– the parietal
pericardium reflects
back and covers theheart
Membranes of the Lungs• Parietal pleura
–this serous
membrane
lines the walls
of the thoracic
cavity
Parietal pleura
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Membranes
• Visceral pleura
– this serous
membrane
covers the lungs
Visceral pleura
Membranes of the
Abdominopelvic Cavity
• Parietal
peritoneum
– is associated with
the walls of the
abdominopelvic
cavityParietal peritoneum
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• Visceral
peritoneum
– covers most of
the organs within
the
abdominopelvic
cavityVisceral peritoneum
Microscope• In biology, it is imperative that the student be
proficient in the use of the microscope
• All biology students should be able to focus on asmear in less than three minutes with anymicroscope
• Initially, you must learn the parts of themicroscope, the function of each part, and finally
the care and the maintenance of the microscope• Ideally, at the conclusion of this exercise, you
should be well on your way to success in the useof the microscope
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Microscope
• Ocular (eyepiece)
– usually a 10 power
(lOX) lens containing
a pointer which can
be used to designate
a particular location in
the field of view
Microscope• Body tube
– a tube, quite long in
some microscopes,
which forms the main
body of the microscope;
the ocular is at the top
of the body tube, and a
nosepiece or containingseveral objectives is at
the bottom of the tube
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Microscope
• Coarse adjustment
– a knob which raises
and lowers the body
tube to bring the
specimen on the slide
into focus
Microscope
• Fine adjustment
– a knob to be used
for fine adjustment
(focusing) after
using the coarse
adjustment
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Microscope
• Nosepiece
– a turret that holds
the objectives and
allows them to pivot
into position as
needed
Microscope• Objectives
– there are usually four objectivelenses, but some nosepieceshave fewer; they are a 4Xscanning lens, a 10X lowpower, a 40X-45X high power,and a 100X oil immersion
– On many microscopes, theobjectives are identified by colorbands: green for low power,yellow for high power, and red
for oil immersionWhat would be the total
magnification when using any
of these objectives?
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Microscope
• Spring clips or
Mechanical slide
holder
– these hold the
glass slide in
position on the
stage
Microscope• Stage
–a platform on
which the slide is
placed
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Microscope
• Diaphragm
– regulates the size ofthe light opening inthe stage, thusregulating the amountof light passingthrough the specimen
– proper control of theamount of light is
nearly as important asproper focusing forviewing the specimen
Microscope• Illuminator
– a sub-stage light ormirror is enclosed in thebase of somemicroscopes
– If the light source is notsufficient, the fullcapabilities of amicroscope cannot berealized. Turn this lightoff when not in use; theswitch usually liesbehind the light
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Microscope
• Arm
– the main supportive
structure of the
microscope, and the
only part except the
base by which the
instrument should be
carried
Microscope• Base
– the supportive bottom
of the instrument that
holds the light
source
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Microscope
• Condenser – a lens system locked into the
light opening of the stage ofmany microscopes (not presenton all)
– the condenser focuses orconcentrates the light from theilluminator on the specimen
– the condenser can be adjustedto a higher or lower position bya substage adjustment knobbut for most purposes, thecondenser should be fullyraised
– if a pattern appears in the field
of view, you lower thecondenser until the patterndisappears
ACTIVITY-MICROSCOPE
• Get out a microscope
• Learn the various parts
– Ocular
– Objectives
• 4x, 10x, 40x
– Stage
– Course adjustment
– Fine adjustment
– Diaphragm
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TISSUES• Tissues are a group of cells that have
a similar structure, and are specializedfor a specific function.
• The four main types of tissues are;
– Epithelial
– Connective
– Muscle
– Nerve
4 MainTypes of Tissue• Epithelial Tissue
– Simple
– Stratified
– Pseudostratified
• Connective Tissue – Loose
– Dense
– Cartilage
– Bone
– Blood
• Muscle Tissue – Cardiac
– Smooth
– Skeletal
• Nervous Tissue
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1-EPITHELIAL TISSUE
Characteristics of Epithelial Tissue
i) Cellularity
– composed almost entirely of cells
ii) Special contacts
– form continuous sheets held together by tight
junctions and desmosomesiii) Polarity
– apical and basal surfaces
Characteristics of Epithelial Tissue
iv) Supported by connective tissue
– reticular and basal laminae
v) Avascular but innervated
– contains no blood vessels but supplied
by nerve fibers
vi) Regenerative
– rapidly replaces lost cells by cell division
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Epithelial Tissue
• Classified by presence oflayers and shapes
• Classification by layers
– Simple
• One layer
– Stratified
• Many layers
– Pseudostratified
• Single layer
• Appears multilayered
Types of Epithelial Tissue1) Simple squamous
– Location
• blood vessels, lining the
heart (visceral pericardium),
air sacs of the lung, kidney
(Bowman’s capsule)
– Function
• Diffusion and filtration,
secretion of lubricating
substances in the serosae – Special features
• flat single layered cells,
square to octagonal shape,
central nucleus
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Epithelial Tissue
2) Simple cuboidal – Location
• kidney tubules, ovary,
ducts and secretory
portions of small glands
– Function
• secretion and
absorption
– Special features
• single layered, cube
shaped, central nucleus
Epithelial Tissue3) Simple columnar
– Location
• gastrointestinal (GI)
tract, gallbladder, and
excretory ducts of some
glands
– Function
• secretion “mucus” and
absorption “nutrients”
– Special features
• column shaped, goblet
cells, microvilli
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Epithelial Tissue
4) Pseudostratifiedciliated columnar
– Location• upper respiratory tract
(trachea, nasal cavity,etc.) and male urethra
– Function• secretion of mucus and
movement by cilaryaction
– Special features• cilia and scattered
nuclei
Epithelial Tissue5) Stratified squamous
– Keratinized and non-keratinized
– Location• skin, vagina, mouth,
esophagus
– Function• Protection
– Special features• layers of cells and
dark basementmembrane
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Epithelial Tissue
6) Transitional – Location
• urinary tract (urethra,
ureter, urinary
bladder)
– Function
• Stretching and
distension
– Special features
• dome shaped cells
with centralized
nuclei
2- CONNECTIVE TISSUE
Structural Elements of Connective Tissue
• Cells
– fibroblasts, chondroblasts, osteoblasts, and
hematopoietic stem cells
• Matrix
– Ground substance
• unstructured material that fills the spacebetween cells
– Fibers
• collagen, elastic, or reticular
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Cells
• Fibroblasts – collagen and elastin
• Chondroblasts
– cartilage
• Osteoblasts
– bone
• Hematopoietic stem cells
– blood
• White blood cells, plasma cells,macrophages, and mast cells
Fibers• Collagen
– tough; provideshigh tensilestrength
• Elastic
– long, thin fibersthat allow forstretch
• Reticular – branched
collagenous fibersthat form delicatenetworks
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Types of Connective Tissue
i) Loose Connective Tissue
a) Areolar
– Location
• surrounds capillaries and
distributed under epithelial
– Function
• wraps and cushions organs
– Special features
• scattered fibers
Loose Connective Tissue
b) Reticular
– Location
• spleen, bone
marrow, and lymph
nodes
– Function
• frame work (stroma)
of various organs
– Special features
• reticular fibers and
blood cells
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Loose Connective Tissue
c) Adipose – Location
• around the heart andkidney, under the skin,posterior portion of theeye
– Function• energy storage, thermal
regulation, support andprotects organs
– Special features
• Cells with large fat(triglycerides) vacuolesthat push the nuclei tothe periphery
ii) Dense Connective Tissue
a) Dense regular
– Location
• tendons (attach
muscle to bone)
and ligaments
(attach bone to
bone)
– Function
• strong attachment
– Special features
• collagen fibers in
waves
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b) Dense irregular – Location
• dermis of theskin
– Function
• strength andwithstandstension
– Special features• collagen fibers in
waves
Dense Connective Tissue
iii) Elastic Connective Tissue
• Elastic connective
– Location
• elastic artery walls
and lung
– Function
• elasticity
– Special features
• scattered elastic
fibers
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iv) Cartilage
a) Hyaline cartilage
– Location
• trachea, ends of long
bones, tip of the nose
– Function
• supports, cushioning,
and resists stress
– Special features
• a vast number ofchondrocytes in
lacuna, collagen
Cartilageb) Elastic Cartilage
– Location
• external ear (pinna)
and epiglottis
– Function
• shape and structure
– Special features
• vast number of
elastic fibers
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Cartilage
c) Fibrocartilage
– Location
• intervertebral disc,
pubic symphysis,
discs of knee joint
– Function
• strength and
absorbs shock
– Special features• thick collagen
fibers
v) BONE• Bone
– Location
• skeletal system
(bones)
– Function
• protection,
support, blood
production – Special features
• osteons
(haversion
systems)
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Vi) BLOOD
• Blood
– Location
• blood vessels and
heart
– Function
• protection, regulation,
transportation
– Special features
• red blood cells (RBC),white blood cells
(WBC), plasma
WBC
RBC
Plasma
3-MUSCLE TISSUESa) Skeletal Muscle
– Location
• skeletal system
(gross muscles)
• attached to bone
– Function
• voluntary movement
and generate heat
– Special features
• striations and
cylindrical fibers
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Muscle Tissue
b) Cardiac Muscle – Location
• heart wall
– Function• Pumps blood
through involuntarymovement.
– Special features• striations,
intercalated disc,centralized nuclei,and branches
Muscle Tissuec) Smooth Muscle
– Location• Hallow organs, blood
vessels, andgastrointestinal tract
– Function• involuntary
propulsion(movement) of
substances – Special features
• non-striated fiberswith centralizednuclei
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4-NERVOUS TISSUE• Neuron
– Location
• central and
peripheral nervous
system
– Function
• action potential and
nerve impulse
– Special features
• dendrites, axon, cell
body (soma)
THE SKIN• Epidermis
– the outermost layer of the skin
– It forms the waterproof, protective wrap over thebody's surface and is made up of stratifiedsquamous epithelium
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The Skin
• Epidermis
– Stratum corneum(Horny layer)
• keratin
• 25-30 cell layersthick
• top layer of deadcells (dry skin anddandruff)
• provides a durableovercoat forprotection
• Epidermis
– Stratum lucidum
(Clear layer )
• visible in the palms
of our hands and
soles of our feet
(thick skin layers)
The Skin
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The Skin
• Epidermis – Stratum granulosum
(Granular layer)• Contain Dying cells
• keratohylinegranules which formkeratin
• contain lamellatedgranules whichcontain awaterproofingglycolipid
The Skin• Epidermis
– Stratum spinosum
(Prickly layer)
• contain
keratinocytes and
Langerhans’ cells
• among the
keratinocytes aremelanin granules
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The Skin
• Epidermis
– Stratum basale
(Basal layer) or
stratum
germinativum
• continually
dividing cells
(mitosis)
The Skin• Dermis (composed of two sub-layers)
– One layer of skin beneath the epidermis that
consists of connective tissue and cushions thebody from stress and strain
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The Skin
• Dermis – Papillary region (layer)
• contains dermal papillae
• Ridges which form the bases for forming our
fingerprints
Accessory Structures• Meissner’s corpuscles
– in dermal papillae
– touch receptors
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Accessory Structures
• Free nerve endings
– in dermal papillae
– pain receptors
The Skin• Dermis
– Reticular region (layer)
• Stretch-recoil properties
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Accessory Structures
• Hair shaft – part of the hair that is above the skin
• Hair root
– part of the hair buried in the follicle under
the skin
Accessory Structures
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• Hair bulb – this area is expanded resembling a bulb
– a knot of sensory nerve endings
Accessory Structures
• Papilla of hair
– At the base of the follicle is a largestructure that is called the papilla
Accessory Structures
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• Hair follicle – Is part of the skin that grows hair by
packing old cells together
Accessory Structures
• Arrector pili muscle
– a bundle of smooth muscle cells
– produces goose bumps (raiser of hair)
Accessory Structures
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Accessory Structures
• Sebaceous (oil) glands
– secrete an oily substance called sebum
Accessory Structures• Sweat (sudoriferous) glands
– two types eccrine and apocrine
– eccrine the most abundant
– eccrine secretes a hypotonic filtrate (sweat) of the
blood
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The Skin• Hypodermis or Superficial fascia (not part of the skin,
but shares some of the skins protective properties)
– anchors skin to the underlying structures (mostly muscles)
• subcutaneous tissue mostly composed of adipose cells
Accessory Structures
• Pacinian corpuscles
– deep pressure receptor