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BACTERIOLOGICAL REVIEWSAIMS AND SCOPE
Bacteriological Reviews is published under the auspices of the American Society forMicrobiology to provide authoritative critical surveys on the current status of subjects andproblems in the diverse fields of microbiology and cognate disciplines, such as immunologyand genetics. This scope includes the occasional short monograph, incorporating and sum-mating original investigations of such breadth and significance that they would lose cogencyif published as a series of research papers. Bacteriological Reviews provides opportunity forthe expert to interpret his special knowledge for the benefit of the main body of micro-biologists. Both established workers and students just beginning research perforce dependincreasingly on compendia for knowledge of progress outside the scope of their trainingand research interests.
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Henry W. ScherpNational Institute of Dental Research
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AUTHOR INDEX
Volumes 23 to 25-1959 to 1961
Albrink, Wilhelm S., 1961, 25, 268-273Andrews, Justin M., 1961, 25, 362-377Angus, T. A., 1960, 24, 266-288Attardi, Giuseppe, 1959, 23, 213-223Austrian, Robert, 1960, 24, 261-265
Bang, Frederik B., 1961; 25, 228-236Barksdale, Lane, 1959, 23, 202-212Beck, Patricia N., 1961, 25, 152-161Benacerraf, Baruj, 1960, 24, 35-40Benenson, Abram S., 1961, 25, 285-293Bennett, Ivan L., Jr., 1960, 24, 16-34Bergersen, F. J., 1960, 24, 246-250Beutner, Ernst H., 1961, 25, 49-76Bibby, Basil G., 1961, 25, 131-141Bridges, Robert A., 1960, 24, 115-132Briody, Bernard A., 1959, 23, 61-95Brock, Thomas D., 1961, 25, 32-48Bryant, Marvin P., 1959, 23, 125-153Burk, Dean, 1961, 25, 447-456
Chance, H. L., 1959, 23, 254-260Cluff, Leighton E., 1961, 25, 362-377Cohn, Melvin, 1959, 23, 213-223Cohn, Zanvil A., 1960, 24, 96-105Condie, Richard M., 1960, 24, 115-132Cox, Herald R., 1961, 25, 383-388
Davenport, Fred M., 1961, 25, 294-300Dingle, John H., 1961, 25, 362-377Dmochowski, Leon, 1959, 23, 18-40
Edwards, Philip R., 1959, 23, 155-174Eichenwald, Heinz F., 1961, 25, 274-281Elberg, Sanford S., 1960, 24, 67-95Evans, Charles A., 1960, 24, 341-352
Fasso, Lois A., 1961, 25, 274-281Fife, Mary A., 1959, 23, 155-174Fletcher, Donald W., 1960, 24, 397-416Francis, Thomas, Jr., 1961, 25, 362-377Friedman, Herman, 1960, 24, 309-339Furcolow, Michael L., 1961, 25, 301-309
Gilmour, Marion N., 1961, 25, 131-141, 142-151,152-161
Ginsberg, Harold S., 1960, 24, 141-150Glassman, Harold N., 1961, 25, 362-377Gochenour, William S., 1961, 25, 285-293Good, Robert A., 1960, 24, 115-132Goodlow, Robert J., 1961, 25, 182-187Gowen, John W., 1960, 24, 192-200Graham, Angus F., 1959, 23, 224-231
Hahon, Nicholas, 1961, 25, 459-476Halvorson, H. Orin, 1959, 23, 267-272Harris, Henry, 1960, 24, 3-15Hartsell, Stanley E., 1959, 23, 250-253Haskins, Willard T., 1961, 25, 427-436Hatch, Theodore F., 1961, 25, 237-240Heimpel, A. M., 1960, 24, 266-288Henderson, David W., 1960, 24, 167-176Hirsch, James G., 1959, 23, 48-60-, 1960, 24, 133-140Horibata, Kengo, 1959, 23, 213-223Howell, Arden, Jr., 1961, 25, 131-141, 162-171Hungate, Robert E., 1960, 24, 353-364
Ingraham, J. L., 1959, 23, 97-108
Kass, Edward H., 1960, 24, 177-185Kotsevalov, Olga, 1961, 25, 274-281
Lamanna, Carl, 1961, 25, 323-330Landy, Maurice, 1961, 25, 427-436, 437-446, 447-
456Langmuir, Alexander D., 1961, 25, 173-181, 356-
358, 362-377Lennox, Edwin S., 1959, 23, 213-223Leonard, Frederic A., 1961, 25, 182-187Levine, Hillel B., 1961, 25, 310-320Lichstein, Herman C., 1959, 23, 261-266Lockhart, W. R., 1959, 23, 8-17Lwoff, Andre, 1959, 23, 109-124
MacLeod, Colin M., 1960, 24, 2Mandelstam, J., 1960, 24, 289-308Marcus, Philip I., 1959, 23, 232-249McCrumb, Fred R., Jr., 1961, 25, 262-267McDermott, Walsh, 1961, 25, 362-377Meyer, Karl F., 1961, 25, 249-261Michael, J. Gabriel, 1961, 25, 437-446Middlebrook, Gardner, 1961, 25, 331-346Milner, Kelsey C., 1961, 25, 427-436Moat, Albert G., 1960, 24, 309-339
Nagai, H., 1961, 25, 404-426Nagai, S., 1961, 25, 404-426Nelson, Norton, 1961, 25, 362-377Nicastri, Anthony, 1960, 24, 16-34Nilsson, Gerda, 1959, 23, 41-47
Oeding, Per, 1960, 24, 374-396
Pappagianis, Demosthenes, 1961, 25, 310-320Perkins, William A., 1961, 25, 347-355Petty, Milton A., 1961, 25, 111-130
477
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AUTHOR INDEX
Pine, Leo, 1961, 25, 162-171Porter, J. R., 1961, 25, 389-403
Ramsey, Carolyn H., 1959, 23, 155-174Ravin, Arnold W., 1960, 24, 201-220Ribi, Edgar, 1961, 25, 427-436Riley, Richard L., 1961, 25, 243-248Rogers, David E., 1960, 24, 50-66Rothstein, Aser, 1959, 23, 175-201Rotman, Boris, 1960, 24, 251-260Rowe, Wallace P., 1961, 25, 18-31Rowley, Derrick, 1960, 24, 106-114
Saito, Margaret, 1961, 25, 310-320Salton, M. R. J., 1961, 25, 77-99Schneider, Howard A., 1960, 24, 186-191Skinner, Charles E., 1960, 24, 397-416Smith, Charles E., 1961, 25, 310-320Stanier, R. Y., 1961, 25, 1-17Steinhaus, Edward A., 1960, 24, 365-373Stetson, Chandler A., Jr., 1961, 25, 457-458
Stokes, J. L., 1959, 23, 97-108Strange, R. E., 1959, 23, 1-7Sulkin, S. Edward, 1961, 25, 203-209
Tigertt, William D., 1961, 25, 285-293
Vaughan, L. M., 1961, 25, 347-355
Wagner, Robert R., 1960, 24, 151-166, 1961, 25, 100-110
Wedum, Arnold G., 1961, 25, 210-216Whitby, James L., 1961, 25, 437-446, 447-456Wolfe, Elwood K., Jr., 1961, 25, 194-202Wood, W. Barry, Jr., 1960, 24, 41-49
, 1961, 25, 362-377Woods, Mark W., 1961, 25, 437-446, 447-456Wright, George W., 1961, 25, 219-227
Yanagishima, N., 1961, 25, 404-426Yanofsky, Charles, 1960, 24, 221-245
Zentner, Robert J., 1961, 25, 188-193
478 [VOL. 25
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SUBJECT INDEX
Volumes 23 to 25-1959 to 1961
Aerosol, infection of man, with Pasteurella tula-rensis, 1961, 25, 262-267
-, techniques for formation of, 1961, 25, 188-193Aerosols, quantitative characterization of, 1961,
25, 194-202Airborne coccidioidomycosis, 1961, 25, 310-320- histoplasmosis, 1961, 25, 301-309- infection, control of, in laboratory, 1961, 25,
210-216- -, critique of Conference on, 1961, 25, 362-377
-, epidemiology of, 1961, 25, 173-181, inhalation of toxins in, 1961, 25, 323-330
-, public health aspects of, 25, 347-358-, reactions to inhaled antigens in, 1961, 25,331-346
- microorganisms, viability and infectivity of,1961, 25, 182-187
- pulmonary tuberculosis, 1961, 25, 243-248- Q fever, 1961, 25, 285-293Anatomy of bacterial surface, 1961, 25, 77-99Anthrax, inhalation, pathogenesis of, 1961, 25,
268-273Antibody, fluorescent, for immunofluorescent
staining, 1961, 25, 49-76- synthesis, at cellular level, 1959, 23, 213-223Antimicrobial factors, in tissues and phagocytic
cells, 1960, 24, 133-140Arizona group, of Enterobacteriaceae, 1959, 23,
155-174
Bacillus species, cell wall lysis and peptide release,1959, 23, 1-7
Bacteria, encapsulated, phagocytosis in, 1960,24, 41-47
-, lysogenic conversions in, 1959, 23, 202-212, outgrowth of, 1959, 23, 267-272
-, photosynthetic mechanisms of, 1961, 25, 1-17, psychrophilic, 1959, 23, 97-108, rumen, 1959, 23, 125-153
Bacterial endotoxins, chemical composition,related to biological activity of, 1961, 25,427-436
- , immunological aspects of host reaction to,1961, 25, 457-458
-, increased nonspecific resistance to infectionevoked by, 1961, 25, 437-446
- , metabolic effects on mammalian cells, 1961,25, 447-456
- insecticides, 1960, 24, 266-288- interference, in nonspecific resistance to infec-
tion, 1960, 24, 167-176
- nitrogen fixation, legume root nodules in, 1960,24, 246-250
- species, origin of, 1960, 24, 201-220- surface, anatomy of, 1961, 25, 77-99Bacterionema matruchotii, growth and biochemical
characteristics of, 1961, 25, 152-161-, physiological and biochemical character-istics of, 1961, 25, 162-171
- -, reproduction of, 1961, 25, 142-151Biosynthesis, purine derivatives, 1960, 24, 309-339Blood stream, host mechanisms for removal of
bacteria from, 1960, 24, 50-66
Candida, genus, 1960, 24, 397-416Cell, biology of, modified by virus or antigens,
1959, 23, 202-231-, growth, changes in early phases of, 1959, 23,
254-260-,-, physiological aspects of, 1959, 23, 261-266
membrane, in metabolism of inorganic electro-lytes, 1959, 23, 175-201
, metabolism, relation to infection with rickett-sial and bacterial agents, 1960, 24, 96-105
-wall, lysis and peptide release, 1959, 23, 1-7Cells, immunity, 1960, 24, 67-95
, mammalian, viral biosynthesis in, 1959, 23,224-231
Chloramphenicol, 1961, 25, 32-48Coccidioidomycosis, human, 1961, 25, 310-320Cytology, changes in early growth phases, 1959,
23, 254-460
Differentiation, biochemical, intracellular turn-over of protein and nucleic acids in, 1960, 24,289-308
Dormancy, in bacterial growth, 1959, 23, 267-272Dysproteinemias, host-parasite relationships in
patients with, 1960, 24, 115-132
Ectromelia, response of mice to, 1959, 23, 61-95Endotoxins, bacterial, immunological aspects of
the host reaction to, 1961, 25, 457-458, increased resistance to infection evoked by,
1961, 25, 437-446- -, metabolic effects on mammalian cells, 1961,
25, 447-456relationship of chemical composition to
biological activity of, 1961, 25, 427-436Enterobacteriaceae, Arizona group, 1959, 23, 155-
174
Fever, as mechanism of resistance to infection,1960, 24, 16-34
479
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SUBJECT INDEX
Fluorescent antibody, for immunofluoreseentstaining, 1961, 25, 49-76
Genetic effects, in nonspecific resistance to infec-tious disease, 1960, 24, 192-200
- recombination, in origin of bacterial species,1960, 24, 201-220
Germination, bacterial, 1959, 23, 267-272Gram stain, and etiology of lobar pneumonia,
historical note, 1960, 24, 261-265Growth, bacterial, initiation of, 1959, 23, 250-253
, initiation, physiological aspects of, 1959, 23,261-266
Halometabolites, microbial, origin and biochem-istry of, 1961, 25, 111-130
Histoplasmosis, airborne, 1961, 25, 301-309Hormones, host resistance to infection and, 1960,
24, 177-185Host, mechanisms, in removal of bacteria from
blood stream, 1960, 24, 50-66-, resistance, to infection, hormones in, 1960, 24,
177-185nutritional factors in infection, 1960, 24,
186-191- , relationship of viral interference to, 1960,24, 151-166
Host-parasite relationships, in patients withdysproteinemias, 1960, 24, 115-132
Immunity, cellular, 1960, 24, 67-95, infectious disease, Metchnikoff's concepts of,
1959, 23, 48-60Immunofluorescent staining, fluorescent antibody
method for, 1961, 25, 49-76Infection, airborne, critique of Conference on,
1961, 25, 362-377immunological aspects of inhalation of
toxins in, 1961, 25, 323-330--- reactions to inhaled antigens in
1961, 25, 331-346,-, public health aspects of, 1961, 25, 347-358
viability and infectivity of microorganismsin, 1961, 25, 182-187
, bacterial, acquired resistance to, in insects,1961, 25, 100-110
, fever as mechanism of resistance to, 1960, 24,16-24
, inflammatory tissue, mobilization of defensivecells in, 1960, 24, 3-15
, nonspecific resistance to, defined, 1960, 24, 2, relation of antibacterial systems of serum, and
nonspecific immunity to, 1960, 24, 106-114cell metabolism to, with rickettsial and
bacterial agents, 1960, 24, 96-105, resistance to, influence of radiation on, 1960,
24, 35-40
structure and function of respiratory tract inrelation to, 1961, 25, 219-227viral-bacterial interaction in, 1961, 25, 274-281
Infections, laboratory-acquired, 1961, 25, 203-209Infectious disease, genetic effects in nonspecific
resistance to, 1960, 24, 192-200immunity, Metchnikoff's concepts of, 1959,23, 48-60
Influenza, pathogenesis of, 1961, 25, 294-300Inhalation anthrax, pathogenesis of, 1961, 25,
268-273Inhaled particles, distribution and deposition of,
in respiratory tract, 1961, 25, 237-240Insecticides, bacterial, 1960, 24, 266-288Insect-microbe ecosystem, environmental factors
effecting, 1960, 24, 365-373Insects, acquired resistance to bacterial infection
in, 1961, 25, 100-110Ion exchange resins, use in microbiology, 1960, 24,
251-260Irradiation, influence on resistance to infection,
1960, 24, 35-40
Laboratory airborne infection, control of, 1961,25, 210-216
Leptotrichia, classification of organisms so termed,1961, 25, 131-141
Lobar pneumonia, etiology, and Gram stain, his-torical note, 1960, 24, 261-265
Metchnikoff concepts of immunity to infectiousdisease, 1959, 23, 48-60
Microbial halometabolites, origin and biochemis-try of, 1961, 25, 111-130
Microorganisms, cell membrane in metabolism ofinorganic electrolytes, 1959, 23, 175-201use in growth and morphogenesis studies, 1959,23, 8-17
Milk, bacteriological grading of, 1959, 23, 41-47reducing properties, in bacteriological gradingof, 1959, 23, 41-47
Morphogenesis, use of microorganisms in study of,1959, 23, 1-7
Mucociliary function, as protective mechanism inupper respiratory tract, 1961, 25, 228-236
Mutation, respiration-deficient, in yeast andother microorganisms, 1961, 25, 404-426
Nitrogen fixation, biochemical pathways inlegume root nodule, 1960, 24, 246-250
Nucleic acids, in biochemical differentiation, 1960,24, 289-308
Nutrition, factor in host resistance to infection,1960, 24, 186-191
"Pasteur. Achievements and disappointments,1861," 1961, 25, 389-403
Pasteurella pestis, in study of pnemonic plague.1961, 25, 249-261
480 [VOL. 25
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SUBJECT INDEX
-tularensis, aerosol infection of man with, 1961,25, 262-267
Peptide, release and cell wall lysis, in Bacillusspecies, 1959, 23, 1-7
Phagocytic cells, antimicrobial factors in, 1960,24, 133-140
Phagocytosis, in encapsulated bacteria, 1960, 24,41-49
Photosynthetic mechanisms, in bacteria andplants, unitary concept of, 1961, 25, 1-17
Pneumonic plague, 1961, 25, 249-261Poliomyelitis, factors influencing occurrence of
illness in, 1960, 24, 341-352- vaccine, oral, 1961, 25, 383-388Polyoma virus infection, mouse, epidemiology of,
1961, 25, 18-31Poxvirus infection in the simian host, 1961, 25,
459-476Protein, in biochemical differentiation, 1960, 24,
289-308Psychrophiles, 1959, 23, 97-108Public health, medical aspects of airborne infec-
tion and, 1961, 25, 356-358--, physical aspects of airborne infection and,
1961, 25, 347-355Purines, biosynthesis and interconversion of, 1960,
24, 309-339
Q fever, airborne, 1961, 25, 285-293
Resins, ion exchange, use in microbiology, 1960,24, 251-260
Respiration-deficient (RD) mutation, in yeast,1961, 25, 404-426
Respiratory tract, distribution and deposition ofinhaled particles in, 1961, 25, 237-240
- , mucociliary function as protective mech-anism in, 1961, 25, 228-236
- , structure and function, in relation to infec-tion, 1961, 25, 219-227
Rumen, bacterial species of, 1959, 23, 125-153
-, microbial ecology of, 1960, 24, 353-364
Serum, antibacterial systems, relation to non-specific immunity to infection, 1960, 24, 106-114
-, inhibitors of virus, 1960, 24, 141-150Smallpox infection in the simian host, 1961, 25,
459-476Staphylococci, aerial dissemination of, effects of
viral infection on, 1961, 25, 274-281Staphylococcus aureus, antigenic properties of,
1960, 24, 374-396
Tissues, antimicrobial factors in, 1960, 24, 133-140, inflammatory, mobilization of defensive cells
in, 1960, 4, 3-15, inhibitors of virus, 1960, 24, 141-150
Tryptophan synthetase, biosynthesis of, 1960, 24,221-245
Tuberculosis, airborne pulmonary, 1961, 25, 243-248
Tumors, recent advances in study of, 1959, 23,18-40
Vaccine, oral poliomyelitis, 1961, 25, 383-388Viral biosynthesis, mammalian cells, physiological
conditions for study of, 1959, 23, 224-231- disease, evolution, at cellular level and in the
organism, 1959, 23, 109-124- interference, relationship to host resistance,
1960, 24, 151-166Virus, poliomyelitis, factors influencing occur-
rence of illness in naturally acquired infec-tions, 1960, 24, 341-352
-, polyoma, epidemiology of mouse infection,1961, 25, 18-31
-, recent advances in study of, 1959, 23, 1S-40-, serum and tissue inhibitors of, 1960, 24, 141-150
vaccinia, response of mice to, 1959, 23, 61-95Virus-host interactions, single-cell techniques in
tracing, 1959, 23, 232-249
19611 481
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BACTERIOLOGICALREVIEWS
VOLUME 25
BALTIMORE, MD.1961
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CONTENTS
No. 1, MARCH
Photosynthetic Mechanisms in Bacteria and Plants: Development of a UnitaryConcept. R. Y. STANIER................................................... 1- 17
The Epidemiology of Mouse Polyoma Virus Infection. WALLACE P. ROWE...... 18- 31Chloramphenicol. THOMAS D. BROCK........................................... 32- 48Immunofluorescent Staining: The Fluorescent Antibody Method. ERNST H.
BEUTNER................................................................... 49- 76
No. 2, JUNE
The Anatomy of the Bacterial Surface. M. R. J. SALTON...................... 77- 99Acquired Resistance to Bacterial Infection in Insects. ROBERT R. WAGNER...... 100-110An Introduction to the Origin and Biochemistry of Microbial Halometabolites.
MILTON A. PETTY.......................................................... 111-130The Classification of Organisms Termed Leptotrichia (Leptothrix) buccalis.
I. Review of the Literature and Proposed Separation into Leptotrichia buccalisTrevisan, 1879 and Bacterionema gen. nov., B. matruchotii (Mendel, 1919)comb. nov. MARION N. GILMOUR, ARDEN HOWELL, JR., AND BASIL G. BIBBY. 131-141
II. Reproduction of Bacterionema matruchotii. MARION N. GILMOUR.......... 142-151III. Growth and Biochemical Characteristics of Bacterionema matruchotii.
MARION N. GILMOUR AND PATRICIA N. BECK............................... 152-161IV. Physiological and Biochemical Characteristics of Bacterionema matruchotii.
ARDEN HOWELL, JR., AND LEO PINE....................................... 162-171
No. 3, SEPTEMBER
CONFERENCE ON AIRBORNE INFECTION
Foreword............................................................................ viiPART I. Keynote Address: Epidemiology of Airborne Infection. ALEXANDER D.
LANGMUIR........................................................... 173-181PART II. Airborne Organisms. NORTON NELSON, Chairman
Viability and infectivity of microorganisms in experimental airborne infection.ROBERT J. GOODLOW AND FREDERIC A. LEONARD .......................... 182-187
Techniques of aerosol formation. ROBERT J. ZENTNER...................... 188-193Quantitative characterization of aerosols. ELWOOD K. WOLFE, JR........... 194-202Laboratory-acquired infections. S. EDWARD SULKIN........................ 203-209Control of laboratory airborne infection. ARNOLD G. WEDUM............... 210-216Discussions of papers on airborne organisms. HAROLD N. GLASSMAN,Rapporteur............................................................... 217-218
Part III. Respiratory System and Airborne Infection. W. BARRY WOOD, JR.,Chairman
Structure and function of respiratory tract in relation to infection. GEORGEW. WRIGHT............................................................... 219-227
Mucociliary function as protective mechanism in upper respiratory tract.FREDERIK B. BANG. 228-236
Distribution and deposition of inhaled particles in respiratory tract.THEODORE F. HATCH.................................................... 237-240
Discussions of papers on respiratory system and airborne infection. LEIGHTONE. CLUFF, Rapporteur. 241-242
PART IV. Bacterial Diseases. JUSTIN M. ANDREWS, ChairmanAirborne pulmonary tuberculosis. RICHARD L. RILEY....................... 243-248Pneumonic plague. KARL F. MEYER........................................ 249-261Aerosol infection of man with Pasteurella tularensis. FRED R. MCCRUMB, JR.. . 262-267
iii
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CONTENTS
Pathogenesis of inhalation anthrax. WILHELM S. ALBRINK.................. 268-273Some effects of viral infection on aerial dissemination of staphylococci and on
susceptibility to bacterial colonization. HEINZ F. EICHENWALD, OLGAKOTSEVALOV, AND LOIS A. FASSO ......................................... 274-281
Discussions of papers on bacterial diseases. PHIi.IP S. BRACHMAN,Rapporteur ............................................................... 282-284
PART V. Virus and Fungus Diseases. THOMAS FRANCIS, JR., ChairmanAirborne Q fever. WILLIAM D. TIGERTT, ABRAM S. BENENSON, AND WILLIAM
S. GOCHENOUR............................................................ 285-293Pathogenesis of influenza. FRED M. DAVENPORT............................ 294-300Airborne histoplasmosis. MICHAEL L. FURCOLOW........................... 301-309Human coccidioidomycosis. CHARLES E. SMITH, DEMOSTHENES PAPPA-
GIANIS, HILLEL B. LEVINE, AND MARGARET SAITO........................ 310-320Discussions of papers on virus and fungus diseases. ROBERT J. GOOD-LOW, Rapporteur......................................... 321-322
Part VI. Immunology and Public Health. LEIGHTON E. CLUFF, ChairmanImmunological aspects of airborne infection: Some general considerations ofresponse to inhalation of toxins. CARL LAMANNA.323-330
Immunological aspects of airborne infection: Reactions to inhaled antigens.GARDNER MIDDLEBROOK .................................................. 331-346
Public health implications of airborne infection: Physical aspects. WILLIAMA. PERKINS AND L. M. VAUGHAN ....... 347-355
Public health implications of airborne infection: Medical aspects. ALEXANDERD.LANGMIR..356-358
Discussions of papers on immunology and public health. ARNOLD G. WEDUrM.Rapporteur.359-361
Part VII. Critique of Conference. WALSH MCDERMOTT, Chairman............ 362-377Index.......................................................................... 379-382
No. 4, DECEMBER
Oral Poliomyelitis Vaccine. HERALD R. Cox................................... 383-388Louis Pasteur. Achievements and Disappointments, 1861. J. R. PORTER........ 389-403Advances in the Study of Respiration-deficient (RD) Mutation in Yeast and Other
Microorganisms. S. NAGAI, N. YANAGISHIMA, AND H. NAGAI............ 404-426Symposium on Bacterial Endotoxins. Maurice Landy, Convener.
Relationship of Chemical Composition to Biological Activity. EDGAR RIBI,WILLARD T. HASKINS, MAURICE LANDY, AND KELSEY C. MILNER............. 427-436
Possible Mechanisms whereby Endotoxins Evoke Increased Nonspecific Resist-ance to Infection. JAMES L. WHITBY, J. GABRIEL MICHAEL, MARK W. WOODS,AND MAURICE LANDY....................................................... 437-446
Metabolic Effects of Endotoxins on Mammalian Cells. MARK W. WOODS,MAURICE LANDY, JAMES L. WHITBY, AND DEAN BURK....................... 447-456
Immunological Aspects of the Host Reaction to Endotoxins. CHANDLER A.STETSON, JR.............................................................. 457-458
Smallpox and Related Poxvirus Infections in the Simian Host. NICHOLAS HAHON.. 459-476Author Index, Vols. 23 to 25...................... 477-478Subject Index, Vols. 23 to 25...................... 479-481
iv
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ANREusURt-BUCH, INC...........................S t. Louis, Mo.AnmoUR AND COMPANY, INC...................... Chicago, Ill.ARTHUR D. LITTLE, INC...................... Cambridge, Mass.
ATERsT LABORATORIES....................... New York, N. Y.
BALTIMORE BIOLOGICAL LABORATORY, DIVISION OF B-D LAno-ZATORuIS, INC............................... Baltimore, Md.
BAUsCH AND LOMB OPTICAL CO ............... Rochester, N. Y.DON BAXTER, INC.............................. Glendale, Calif.
BECTON, DICKINSON AND Co................. Rutherford, N. J.BzuLco GLASS, INC............................. Vineland, N. J.BIOVBRm CORP................................ Wasco, Calif.BORDEN FOODS Co.............................S yracuse, N. Y.
BRAmHALL, DEANE Co....................... New York, N. Y.
BRINKMAN INSTRUMENT, INC.......... Great Neck, L. I., N. Y.
BRISTOL LABORATORIES, INC................... Syracuse, N. Y.
BUCKMAN LABORATORIES, INC. ............... Memphis, Tenn.BU1RGESS PUBLISRING Co................... Minneapolis, Minn.
BURROUGHS, WELLCOME AND CO. ........... New York, N. Y.CAPPEL LABORATORIES, DIv. oP B-D LABORATORIES, INC.
West Chester, Pa.CARwoRTE FARMS, INC.... New City, Rockland County, N. Y.CASE LABORATORIES, INC........................ Chicago, Ill.
CHILEAN IODINE EDUCATIONAL BUREAU, INC... New York, N. Y.CIBA PHARMACEUTICAL PRODUCTS, INC..........Summit, N. J.
COCA COLA Co Atlanta, Ga.
COLORADO SERUM Co... Denver, Colo.COMMERCIAL SOLVENTS CORP................ Terre Haute, Ind.CONSOLIDATED LABORATORIES, INC........Chicago Heights, Ill.
CORNING GLASS WORKS......................... Corning, N. Y.CORN STATES LABORATORIES, INC...............Omaha, Neb.
COULTER ELECTRONICS, INC........................ Chicago,
CUTTER LABORATORIES......................... Berkeley, Calif.
Dico LABORATORIES, INC....................... Detroit, Mich.
DIVERSEY CORP.................................... Chicago, Ill.
Dow CHEMICAL Co.............................M idland, Mich.
EBERBACH CORP.............................. Ann Arbor, Mich.
E. DUPONT DE NEMOURS & Co., INC Wilmington, Del.
FALCON PLASTIC PRODUCTS, DIv. OF B-D LABORATORIES, INC.Los Angeles, Calif.
FISHER SCIENTIFIC Co.......................... Pittsburgh, Pa.
FLEISCHMANN LABORATORIES................. Stamford, Conn.GENERAL BIOLOGICAL SUPPLY HOUSE, INC......... Chicago, Ill.
HAMILTON MFG. CO ........................ Two Rivers, Wisc.
HARTmAN-LEDDON COMPANY................ Philadelphia, Pa.
HEINICKE INSTRUMENT CORP.................. Hollywood, Fla.
HOFFMANN-LA ROCHE, INC....................... Nutley, N. J.
HUNTINGTON LABORATORIES, INC ......... Huntington, Ind.HYLAND LABORATORIES......................LO8 Angeles, Calif.HTNSON, WESTCOTT AND DUNNING ............. Baltimore, Md.
INDUSTRIAL BIOLOGY LABORATORIES, INC.Philadelphia, Pa.INTERNATIONAL EQUIpMENT Co..................Boston, Mass.INTERNATIONAL MINERALS AND CHEMICAL CoRP..-Chicago, I11.JENsEN-S3ALsBERy LABORATORIES, INC.......Kansas City, Mo.KEWAUNEE MANUFACTURING Co................. Adrian, Mich.KINBLE GLASS DIVISION, OWENS-ILLINoin GLAss Co.
Toledo, OhioLABLINE, INc ..................................... Chicago, Ill.LEDERLE LABORATORIES .................. Pearl River, N. Y.E. LEITZ, INC.............................. New York, N. Y.ELI LniLY AND Co........................... Indianapolis, Ind.LOURDEs INSTRUMENT CoRP................... Brooklyn, N. Y.MERCK SHARP AND DOHmE ..................... Rahway, N. J.MILES CHEMICAL Co..............................Clifton, N. J.MILES LABORATORIES, INC.........................Elkhart, Ind.MILLIPORE FILTER CoaP...................... Watertown, Mass.MONARCH CHEMICALS, INC.................. Minneapolis, Minn.NATIONAL DRUG Co.......................... Philadelphia, Pa.NEW BsRUNSWIcK SCIENTIFIC Co........ Now Brunswick, N. J.NITRAGIN CO., INc............................ Milwaukee, Wiwc.NORWICH PHARMACAL CO...................... Norwich, N. Y.OarHo RESEARCH FOUNDATION.................. Raritan, N. J.PARKE, DAVIs AND Co.......................... Detroit, Mich.CHAS. PFIZER AND CO., INC.................. New York, N. Y.PITMAN-MOORE Co., DIV. OF ALLIED LABORATORIES, INC.
Indianapolis, Ind.PHILIP MORRIS, INC............................ Richmond, Va.THE PILLSBURY Co...................... Minneapolis 14, Minn.PROCTER & GAMBLE Co....................... Cincinnati, OhioPROFEasIONAL TAPE Co., INC.................... Riverside, Ill.RED STAR YEAST AND PRODUCTS Co.......... Milwaukee. Wisc.SCHERING Coup............................ Bloomfield, N. J.CARL SCHLEICHER & SCHUELL Co................Keene, N. H.JOSEPH SCHLITZ BREWING Co................. Milwaukee, Wisc.SCHWARZ LABORATORIES, INC............ Mount Vernon, N. Y.SCIENTIC GLASS APPARATUS Co., INC........ Bloomfield, N. J.SCIENTIFIC PRODUCTS............................. Evanston, I11.JOSEPH E. SEAGRAM AND SONS, INC............. Louisville, Ky.G. D. SEARLE & COMPANY........................ Chicago, I11.SELAS CORPORATION OF AMERICA ....... ...... Philadelphia, Pa.SHARP AND DOHME, INC...................... Philadelphia, Pa.SHERMAN LABORATORIES ................. Detroit, Mich.SMITH, KLINE & FRENCH LABORATORIES....Philadelphia, Pa.IVAN SORVALL,INC........................... Norwalk, Conn.SQUIBB INSTITUTE FOR MEDICAL RESEARCH
New Brunswick, N. J.STANDARD SCIENTIFIC SUPPLY CORP.......... New York, N. Y.SUN OIL Co., R & D DIvIsuoN............ Marcus Hook, Pa.SWIFT & COMPANY ................................ Chicago, IllARTHUR H. THOMAS CO...................... Philadelphia, Pa.THE UPJOHN Co.............................Kalamazoo, Mich.VESTAL LABORATORIES, INC......................St. Louis, Mo.WALLERSTEIN Co., INC....................... New York, N. Y.WARNER LAMBERT RESEARCH INSTITUTE..... New York, N. Y.THE WILLIAMS & WILKINS CO.................. Baltimore, Md.WILMOT CASTLE Co........................... Rochester, N. Y.WINTHROP LABORATORIES, INC............... New York, N. Y.WISCONSIN ALUMNI RESEARCH FOUNDATION ... Madison, Wiec.