bachelor of medical laboratory sciences honours degree

1

DEPARTMENT OF MEDICAL LABORATORY SCIENCES

FACULTY OF HEALTH SCIENCES

THE OPEN UNIVERSITY OF SRI LANKA

Course Synopses

Bachelor of Medical Laboratory Sciences

Honours Degree Programme

2

Semester and Level Semester 1– Level 03

Course Code MDU3400

Course Title Basics for Medical Laboratory Sciences

Credit value 04

Core/Optional Core

Prerequisites None

Hourly breakdown Theory Practical Independent Learning Assessment Total

50 hrs

(25 Sessions)

08 hrs

(4 DSs)

24 hrs

(4 days

Lab)

115 hrs

(Sessions [75hrs) +

Practical [12hrs] +

Online [14hrs] +

recommended readings

[14hrs])

03 hrs

(1 CAT x

1.5hrs) + (1

Practical test x

1.5hrs)

200 hrs

Course Aim/s. ● To provide basic knowledge on structural and functional aspects of a medical laboratory

PLOs addressed by

course

● PLO 01: Academic Expertise ● PLO 02: Practical Competence ● PLO 07: Information and Data Management Skills

Course Learning

Outcomes (CLO) The students should be able to: ● CLO 1: Recognize glassware, plastic ware, equipment, reagents and consumables used in

the laboratory and describe principles and uses of different laboratory instruments. (PLO 01) ● CLO 2: Explain theories behind chemical reactions used in laboratory investigations. (PLO

01) ● CLO 3: Explain hazards that can take place in a laboratory, management of these hazards

and to discuss the safety precautions. (PLO 01) ● CLO 4: Perform basic chemical investigations. (PLO 02)

● CLO 5: Describe the basic statistical parameters that are needed for the interpretation of test

and quality control results. (PLO 07)

Content (Main topics, sub

topics)

● Introduction to medical laboratory - Medical laboratory, Laboratory items including

instruments, Glassware and plastic ware

● Laboratory equipment – Basic principles of physics for laboratory instrumentation,

Microscope, Centrifuge, Pipettes, Spectrophotometer and Colorimeter, Balances, Shakers and

Mixers, Instruments for sterilization, Other laboratory equipment

● Basic Chemistry - Atoms ions and molecules, Pure substances and substance mixtures,

Chemical reactions, Properties of solutions, Solutions & ionic reactions, Volumetric analysis,

Radioactivity, Electrochemistry & Thermochemistry

● Safety in the laboratory – Hazards in laboratory and safety measures, Safe handling of

chemicals, Prevention of laboratory infections

● Basic Statistics in medical laboratory – Mean, Median and Mode, Standard deviation and

Coefficient of variation

Teaching Learning

methods

● Self- learning: Course material online (25 Sessions), Online components, Recommended

readings ● Compulsory contact sessions: Laboratory classes - 4 days x 6hrs ● Non-compulsory contact sessions – 4 Day schools ● Continuous assessments: 1 NBT + 1 Practical test (PT) ● Final examination: 1 Theory paper

Assessment

strategy Overall CA Mark (OCAM): 40% Final Assessment: 60%

Theory (50%): NBT: 1 x 1.5hrs ;

10 MCQs (10 marks) + 04 SEQs (80 marks) + 01 Essay

question (10 marks)

Practical (50%): Practical test –1.5hrs

OCAM Computation:

50% NBT + 50% Practical test

Minimum 50% compulsory for PT

Attendance at all PS is compulsory

Minimum OCAM of 40% is required to be eligible for

the Final exam; Eligibility valid only for 2 years

Theory: 100%

1 paper – 3hrs;

30 MCQs (30 marks), 04 SEQs (40 marks)

and 02 Essay Questions (30 marks)

All questions compulsory

3

Recommended Readings:

1. Cheesbrough, M. (2006 or latest edition). District laboratory practice in tropical countries: Part 1.

Cambridge: Cambridge University Press.

2. Seyoum B. (2006 or latest edition), LECTURE NOTES for Medical Laboratory Technology Students,

Introduction to Medical Laboratory Technology.

3. Holmes, H. N. (1941 or latest edition). General chemistry. New York: Macmillan Co.

4

Semester and Level Semester 1 – Level 03

Course Code MDU3401

Course Title Haematology I

Credit value 04

Core/Optional Core

Prerequisites None

Hourly breakdown Theory Practical Independent

Learning

Assessment Total

34hrs

(17 Sessions)

06hrs

(3 DSs)

60 hrs

(10 days

Lab)

96hrs

(Sessions [51hrs]) +

Practical [30 hrs] +

Online [08 hrs] +

Recommended

readings [07 hrs])

04hrs

(1 CAT x 1.5hrs) +

(1 Practical test x

2.5 hrs)

200 hrs

Course Aim/s. ● To provide fundamental knowledge in formation, development, functions and abnormalities

of blood cells and to provide knowledge and skills in routine haematological investigations.

Programme

Learning Outcomes

(PLO) addressed by

course


Course Learning

Outcomes (CLO) The students should be able to:

● CLO 01: Outline the process of blood cell formation, development and their functions. (PLO

01) ● CLO 02: Compare the features of blood cells in normal and disease conditions. (PLO 01) ● CLO 03: Describe the principles of routine haematological tests. (PLO 01) ● CLO 04: Perform routine haematological tests and interpret the results obtained. (PLO 02, 07)


topics)

● Introduction to Haematology - Introduction to blood and its components, Haemopoiesis ● Specimen collection for Haematological testing - Introduction to blood collection, Blood

collection methods ● Changes of blood cells in diseases - Introduction to erythrocyte disorders, Lab diagnosis of

erythrocyte disorders, Introduction to leukocyte disorders, Lab diagnosis of leukocyte

disorders, Introduction to platelet disorders, Lab diagnosis of platelet disorders ● Routine Haematological tests Cell counts and indices, Other routine haematological tests,

Bone marrow smear preparation and staining, Examination of bone marrow cells

Laboratory errors in haematology ● Introduction to hemostasis - Normal hemostasis, Coagulation tests.

Teaching Learning

methods


readings ● Compulsory contact sessions: Laboratory classes - 10 days x 6hrs ● Non-compulsory contact sessions –3 Day schools ● Continuous assessments: 1NBT + 1 Practical test (PT) ● Final examination – 1 Theory paper

Assessment


Theory (50%): NBT: 1 x 1.5hrs:

10 MCQ (10 marks) + 04 SEQs (80 marks) + 01 Essay

question (10 marks)

Practical (50%): Practical test – 2.5hrs

OCAM Computation:

50%NBT + 50% Practical test



Minimum OCAM of 40% is required to be eligible for the

Final exam; Eligibility valid only for 2 years

Theory: 100%

1 paper– 3hrs:

30 MCQs (30 marks), 04 SEQs (40

marks) and 02 Essay Questions (30

marks)


5




2. Bain, B. J., Lewis, S. M., &Dacie, J. V. (2012 or latest edition). Dacie and Lewis practical

haematology. Edinburgh: Elsevier Churchill Livingstone.

3. Hoffbrand, A. V., Moss, P. A. H., & Pettit, J. E. (2006 or latest edition). Essential haematology.

Malden, Mass: Blackwell Pub.

6


Course Code MDU3402

Course Title Medical Bacteriology

Credit value 04

Core/Optional Core

Prerequisites None

Hourly breakdown Theory Practical

Independent Learning Assessment Total

50hrs

(25 Sessions)

08hrs

(4 DSs)

30 hrs

(5 days

Lab)

108hrs

(Sessions [75hrs] +

Practical [15hrs] + Online

[10 hrs] + Recommended

readings [8hrs])

04hrs

(1 CAT x 1.5hrs)

+ (1 Practical

test x 2.5hrs)

200 hrs

Course Aim/s. ● To impart knowledge of basic concepts in bacteriology including nature of bacteria, laboratory

diagnostic techniques and transmission, prevention and control of bacteria and to provide

requisite practical skills to perform standard laboratory procedures in microbiology to identify

medically important bacteria in a safety laboratory environment

PLOs addressed by

course

● PLO 01: Academic Expertise ● PLO 02: Practical Competence ● PLO 03: Effective communication and networking

Course Learning

Outcomes (CLO) The students should be able to: ● CLO 01: Describe morphology and structure, genetics, growth characteristics, human bacteria

relationships, pathogenesis, basics of antimicrobial chemotherapy and resistance. (PLO 01) ● CLO 02: Explain basic principles/concepts and application of laboratory techniques in the

identification of main bacterial pathogens in human and safety laboratory practices (PLO 01) ● CLO 03: Acquire practical skills to identify medically important bacterial species using

standard laboratory techniques including staining techniques, culture techniques,

biochemical and serological tests. (PLO 02) ● CLO 04: Demonstrate standard safe practices in the laboratory. (PLO 02) ● CLO 05: Communicate information clearly, both verbally and in written. (PLO 03)


topics)

● Medical bacteriology- Introduction to bacteria, General properties of bacteria, Introduction to

medical bacteriology ● Identification techniques-Bacterial culture, inoculation techniques, Biochemical tests,

serological and molecular tests ● Prevention and control of bacteria – Sterilization and disinfection of bacterial agents,

Antibiotics and antibiotic resistance, Principles of laboratory safety in microbiology

laboratory. ● Medically important bacteria - Gram-positive cocci (Staphylococci, Streptococci), Gram-

positive bacilli, Enteric Gram-negative bacilli, Pseudomonas and other non-enteric Gram-

negative bacilli, Vibrio, Campylobacter and Helicobacter, Parvobacteria, Neisseria, Anaerobes,

Mycobacteria, Spirochetes, Mycoplasma, Chlamydia and Rickettsia

Teaching Learning

methods


readings ● Compulsory contact sessions: Laboratory classes - 05 days x 6hrs ● Non-compulsory contact sessions – 4 Day schools ● Continuous assessments: 1NBT + 1 Practical test (PT) ● Final examination: 1 Theory paper

Assessment strategy Overall CA Mark (OCAM): 40% Final Assessment: 60%

Theory (50%): NBT: 1x 1.5 hrs ;

10 MCQs (10 marks) + 04 SEQs (80 marks) + 01

Essay question (10 marks)

Practical (50%): Practical test – 2.5 hrs

OCAM Computation:




Minimum OCAM of 40% is required to be eligible

for the Final exam; Eligibility valid only for 2 years

Theory: 100%

1 paper: 3hrs; 30 MCQs (30 marks), 04

SEQs (40 marks) and 02 Essay Questions

(30 marks)


7


1. Ash L. A. and Oriel T.C. A Guide to Laboratory procedure and Identification. American

Society of Clinical Pathologists. Chicago – Latest edition

2. Atlas R. Principles of Microbiology, Mosby Publishers – Latest edition

3. Cheesbrough Monica. Medical Laboratory Manual for Tropical Countries. Vol: 1 &11,

Butterworth- Heinmann Ltd. Oxford – More Advanced Edition

4. Isenberg, Henry D. (editor). Clinical Microbiology Procedures Handbook – Latest edition

5. Laboratory Biosafety Manual. World Health Organization– Latest edition

6. World Health Organization Manual of Basic techniques for a Health laboratory. Geneva –

Latest edition

8


Course Code MDU3303

Course Title Clinical Biochemistry I

Credit value 03

Core/ Optional Core

Prerequisites None

Hourly Breakdown Theory Practical Independent Learning Assessment Total

42hrs

(21 Sessions)

08 hrs

(4 DSs)

18 hrs

(3 days

Lab)

79 hrs

(Sessions [63hrs] +

Practical [09hrs] +

Online [04hrs] +

Recommended readings

[03hrs])

03 hrs

(1 CAT x 1.5 hrs)

+ (1 Practical test

1.5 hrs)

150 hrs

Course Aims ● To provide basic knowledge on structures, functions and metabolic pathways of major

biomolecules and to provide an introduction to clinical biochemistry.

PLOs addressed by

course

● PLO 01: Academic Expertise ● PLO 02: Practical Competence

Course Learning

Outcomes (CLO) The students should be able to: ● CLO 01: Outline basic structures and functions of major types of biomolecules in

human (PLO 01) ● CLO 02: Compare and contrast key structural and functional differences of main

biomolecules. (PLO 01) ● CLO 03: Describe the methods of collection, preservation, transportation and storage of

clinical specimens. (PLO 01) ● CLO 04: Demonstrate competence in specimen collection, preservation and storage.

(PLO 02) ● CLO 05: Describe and Perform basic biochemical analysis of urine. (PLO 01, 02)


topics)

● pH and buffers – Introduction to pH and buffers, Preparation and usages of buffers in

biochemistry. ● Enzymes and enzyme catalyzed reactions - Introduction to enzymes, Enzyme

catalyzed reactions. ● Biochemistry of Carbohydrates – Structure and functions of carbohydrates,

Metabolism of carbohydrates. ● Biochemistry of Amino acids and proteins - Structure and functions of amino acids

and proteins, Proteins and their metabolism. ● Biochemistry of Fats and lipids -Structure and functions of lipids and lipoproteins,

Metabolism of lipids and lipoproteins. ● Biochemistry of Nucleic acids - Structure and functions of nucleic acids, Metabolism of

nucleic acids ● Energy metabolism - Cellular energy metabolism ● Analytical techniques in clinical biochemistry - Analytical techniques in clinical

biochemistry, Point of care testing, Establishment and use of reference values ● Specimen collection in clinical biochemistry– Specimen collection and processing, Pre-

analytical errors ● Urinalysis - Urine collection methods/ types of urine specimens, Physical and chemical

analysis of urine, Urine sediment analysis

Teaching- Learning

methods

● Self- learning: Course material online (21 Sessions), Online components,

Recommended readings ● Compulsory contact sessions: Laboratory classes - 03 days x 6hrs ● Non-compulsory contact sessions – 4 Day schools ● Continuous assessments: 1 NBT + 1 Practical test (PT) ● Final examination: 1 Theory paper

Assessment Strategy Overall CA Mark (OCAM): 40% Final Assessment: 60%

Theory (50%): NBT: 1x 1.5 hrs; 10 MCQs (10 marks) + 04 SEQs (80 marks) + 01 Essay

question (10 marks)

Practical (50%): Practical test –1.5 hrs

OCAM Computation:



Theory: 100%

1 paper: 3 hrs; 30 MCQs (30

marks), 04 SEQs (40 marks) and

02 Essay Questions (30 marks)


9




Recommended

Reading 1. Champe, P. C., Harvey, R. A., & Ferrier, D. R. (2005 or latest edition). Biochemistry.

Philadelphia: Lippincott/Williams & Wilkins.

2. Murray, R. K. (2009 or latest edition). Harper's illustrated biochemistry. New York:

McGraw-Hill.

3. Cheesbrough, M. (2006 or latest edition). District laboratory practice in tropical countries:

Part 1&2. Cambridge: Cambridge University Press.

4. Varley, H., Gowenlock, A. H., McMurray, J. R., McLauchlan, D. M., & Varley, H. (1988

or latest edition). Varley's practical clinical biochemistry. Boca Raton, Fla: CRC Press.

10

Semester and Level Semester I, Level 3

Course Code BSU3230

Course Title Human Anatomy

Credit value 02

Core/ Optional Core

Prerequisites None

Hourly Breakdown Theory Practical Independent Learning Assessments Total

32 hrs

(16 sessions)

6 hrs

(3 DS)

- 63 hrs

(Sessions [48 hrs] + Online


reading [5 hrs])

2 hrs

(2 NBTs x 1hr)

103hrrs

Course Aims ● The main aim of the course is to provide a detailed understanding on the anatomy of the

human body.

PLOs addressed by

course

● PLO1: Theoretical Knowledge ● PLO5: Creativity and problem solving ● PLO7: Information utilization and management

Course Learning

Outcomes (CLO) The students should be able to: ● CLO1: Describe the development and organization of normal body structure (PLO1) ● CLO2: Apply knowledge of human anatomy in clinical practice (PLO1, 5, 7)


topics)

● Introduction to human anatomy: Importance of anatomy, Terminology, Body cavities,

Structural organization ● The cell: Structure of cells, Cell membrane, Cellular organelles, Cell division ● Tissues and organ systems: Tissues of the body, Organs and systems ● Muscle tissue: Skeletal, Cardiac, Smooth muscles ● Circulatory system I- Blood: Composition of blood ● Circulatory system II-The Heart: Structure of the heart and blood flow, Cardiac

conduction system ● Circulatory system III- Blood vessels and Lymphatic system: Structure of blood

vessels, Structure of lymphatic system, Formation and circulation of lymph ● Respiratory system: Air conducting regions – Nose, Pharynx, Larynx, Trachea, Bronchi,

Alveoli, Respiratory mucosa; Voice production, Rib cage, Properties of lung tissue,

Blood and nerve supply ● Gastrointestinal system: Alimentary tract, Structure of alimentary canal, Accessory

digestive organs ● Renal system: Kidney, Nephron, Ureter, Bladder, Blood and nerve supply ● Endocrine system: Classification of hormones, Endocrine glands ● Reproductive system: Male and female reproductive system ● Skeletal muscular system: Attachment of muscles, Muscles of the head, face, neck,

shoulders, forearm, respirations, abdominal wall, joints, pelvic floor, back ● Skeletal system I: Cartilage, Types of bone, Regions of the skeleton, Vertebral column,

Thoracic cage, Appendicular skeleton ● Skeletal system II-Joints and articulation: Classification of joints, Ligaments, Tendons,

Joints of the upper and lower limbs, Ligaments of the vertebral column ● Nervous system and special senses: Nerve tissue, Structure of nervous system, Sensory

receptors, The senses

Teaching- Learning

methods

● Self- learning: course material (printed), Online components, Recommended readings ● Non-compulsory contact sessions: 3 Day schools (DS) ● Continuous Assessments: NBT I and NBT II ● Final Examination: 1 theory paper

Assessment Strategy Overall Continuous Assessment Mark (OCAM): 40% Final Examination: 60%

Theory (100%): NBTs: 2 x 1 hr

20 MCQs (20 marks) + 2 SEQs (80 marks)

OCAM computation:

50% NBT1 mark + 50% NBT2 mark



Theory: 100%

1 paper - 2 hrs, 20MCQs (20

marks) +2SEQs (40 marks)

+2Essay (40 marks)


11

Recommended

Reading 1. Elling, B., Elling, K. M. and Rothenberg, M. A. (2004) Anatomy & Physiology

Paramedic. 1st Edition., Jones & Bartlett publishers. London, U.K ISBN 978-0763737924

2. Tortora, G. J., & Grabowski, S. R. (2000). Principles of anatomy and physiology. 14th

Edition. John Wiley & Sons. New York:, U.S.A.ISBN:978-0-7637-3792-4

3. Waugh, A., Grant, A., & Ross, J. S. (2001). Ross and Wilson anatomy and physiology in

health and illness. Churchill Livingstone Elsevier. Edinburg, Scotland. ISBN: 978-0-

7020-3227-1

4. VanPutte, C. L., Redan, J., Russo, A. & Seeley, R. (2014). Seeley's anatomy & physiology.

11th Edition. McGraw-Hill. New York:, U.S.A ISBN: 9781259671142

12


Course Code MDU3805

Course Title Work Based Training I

Credit value 08

Core/Optional Core

Prerequisites (MDU3400, MDU3401, MDU3402, MDU3303, MDU3306) CR



- 02hrs

(1 DSs)

444 hrs

(74 days

training)

350 hrs

Lab training [222 hrs} +

Reflective journal [74

hrs] + Online [40 hrs] +

Recommended

readings [14 hrs])

04 hrs

(2 Practical tests

x 2 hrs)

800 hrs

Course Aim/s. ● To provide hands on experience in performing routine medical laboratory tests in

biochemistry, bacteriology, parasitology and haematology, and to support learner to

develop competent, ethical and reflective professional practice.

PLOs addressed by

course

● PLO 02: Practical Competence ● PLO 03: Effective Communication and Networking ● PLO 04: Teamwork and Leadership ● PLO 05: Creativity and Problem Solving ● PLO 07: Information and Data Management Skills ● PLO 08: Ethical professional Behaviour

Course Learning

Outcomes (CLO) The students should be able to: ● CLO 01: Perform basic medical laboratory investigations and evaluate test results. (PLO 02,

07) ● CLO 02: Identify errors in pre-analytical, analytical and post- analytical phases of routine

laboratory tests and develop effective plans to minimize errors. (PLO 05) ● CLO 03: Interact with patients and health care professionals in providing effective patient

care. (PLO 03, 04) ● CLO 04: Demonstrate ability in working effectively in different working environments

(PLO 09) ● CLO 05: Demonstrate professional and ethical behavior in the working environment (PLO

08)


topics)

● Introduction to Medical Laboratory ● Biochemistry ● Medical Bacteriology ● Parasitology ● Haematology

Teaching Learning

methods ● Self- learning: Online components, Recommended readings

● Compulsory contact sessions: Laboratory training - 74 days x 6hrs

● Non-compulsory contact sessions – 1 Day school

● Continuous assessments: 2 Practical tests (PT)

● Final examination: 1 Practical test, Reflective journal and Viva voce

Assessment


Practical (100%): Practical tests – 2 x 2 hrs

OCAM Computation:

50% PT1 mark + 50% PT2 mark

Attendance at both PTs and training is

compulsory.

Minimum OCAM of 40% is required to be

eligible for the Final exam; Eligibility valid

only for 2 years

Practical (60%) – Practical test – 3 hrs

Reflective journal (20%)

Viva voce (20%) – Viva voce – 10 mins


1. Lewis S.M., Kumari S. (2000 or latest edition). Guidelines on Standard Operating Procedures

for Haematology. WHO, Reginal Office for South East Asia, New Delhi.

2. Kumari S, Ichhpujani R.L (2000 or latest edition). Guidelines on Standard Operating Procedures

for Microbiology. WHO, Reginal Office for South East Asia, New Delhi.

3. Cheesbrough, M. (2006 or latest edition). District laboratory practice in tropical countries: Part

1&2. Cambridge: Cambridge University Press.

4. Markell, E. K., John, D. T., &Krotoski, W. A. (1999 or latest edition). Markell and Voge's

medical parasitology. Philadelphia: Saunders.

13


Course Code MDU3306

Course Title Medical Parasitology

Credit value 03

Core/Optional Core

Prerequisites None


36 hrs

(18 Sessions)

06 hrs

(3DSs)

24hrs

(4 days Lab)

81 hrs

(Sessions [54 hrs} +

Practical [12 hrs} +

Online [08 hrs] +

Recommended

readings [07 hrs])

03 hrs

(1 CAT x 1.5 hrs)

+ (1 Practical test

x 1.5 hrs)

150 hrs

Course Aim/s. ● To provide knowledge on parasitic diseases of human and their laboratory identifications.

PLOs addressed by

course


Course Learning

Outcomes (CLO) The students should be able to: ● CLO 01: Explain the morphology, life cycle, mode of transmission of the medically important

parasites found in Sri Lanka. (PLO 01) ● CLO 02: Review the epidemiological information available on major parasitic infections in Sri

Lanka. (PLO 01, 07) ● CLO 03: Perform suitable laboratory tests and identify medically important parasites (PLO 02) ● CLO 04: Discuss the appropriate preventive and control measures of parasitic diseases. (PLO

01)


topics)

● Introduction to Parasitology – Introduction to Parasitology, Classification of protozoa and

helminths, Collection, transportation, and storage of specimens.

● Intestinal and genital protozoan parasites - Intestinal Amoebae, Intestinal Flagellates &

Ciliates, Genital Flagellates.

● Intestinal Helminths – Nematodes, Taenia species & other intestinal Cestodes.

● Parasites in circulatory system - Malaria and Babesia, Filarial worms in blood,

Haemoflagellates, Blood, liver and lung flukes

● Tissue parasites -Toxoplasmosis, Opportunistic parasites

● Laboratory techniques in Medical Parasitology – Faecal Concentration techniques,

Laboratory techniques used in the identification of faecal parasites, Laboratory techniques

used in the identification of blood and tissue parasites, Immunodiagnostic techniques and

Rapid diagnostic techniques in parasitology.

Teaching Learning

methods ● Self- learning: Course material online (18 Sessions), Online components, Recommended

readings

● Compulsory contact sessions: Laboratory classes - 04 days x 6hrs

● Non-compulsory contact sessions – 03 Day schools

● Continuous assessments: 1 NBT + 1 Practical test (PT)

● Final examination: 1 Theory paper


Theory (50%): NBT: 1x 1.5 hrs; 10 MCQs (10 marks) + 04 SEQs (80 marks) + 01


Practical (50%): Practical test –1.5 hrs

OCAM Computation:






Theory: 100%

1 paper: 3 hrs; 30 MCQs (30 marks), 04 SEQs

(40 marks) and 02 Essay Questions (30

marks)





2. Markell, E. K., John, D. T., &Krotoski, W. A. (1999 or latest edition). Markell and Voge's medical

parasitology. Philadelphia: Saunders.

14


Course Code MDU3207

Course Title Health Communication

Credit value 02

Core/Optional Core

Prerequisites None


Learning

Assessment Total

30hrs

(15 Sessions)

06 hrs

(3 DSs)

6 hrs (1 day

Practical)

56 hrs

(Sessions [45hrs] +

Practical [3 hrs] +

Online [5 hrs] +

Recommended

readings [3 hrs])

02 hrs

(1 CAT x 1.5 hrs

+ 1 Presentation

x 15min + 1

Debate x

15min)

100hrs

Course Aim/s. ● To explain the importance of effective communication and its applicability in health care

system.

Programme

Learning Outcome

(PLO) addressed by

course

● PLO 01: Academic Expertise ● PLO 03: Effective Communication and Networking

Course Learning

Outcomes (CLO) The students should be able to: ● CLO 01: Describe different methods of communication. (PLO 01) ● CLO 02: Identify barriers in effective communication and how to overcome them. (PLO 01) ● CLO 03: Describe the importance of proper communication in health care system. (PLO 01) ● CLO 04: Practice different types of communication effectively. (PLO 03)


topics)

● Introduction to communication - Definitions and basic assumptions in human

communication, Selected health care related models of communication, Communication in

health care relationships

● Levels and types of communication - Levels of communication, Types of communication,

Nonverbal communication in health care, The nature and dimensions of nonverbal

communication.

● Communication strategies - Active listening, Strategies that encourage conversation,

Strategies that help the patient to express thoughts and feelings, Strategies that insure

mutual understanding ● Reporting and documenting - The importance of reporting, The importance of

documenting, Guide for oral presentations, Guide for written presentations.

Teaching Learning


readings

● Compulsory contact sessions: Practical -1 day x 6hrs


● Continuous assessments: 2 NBTs ● Final examination: 1 Theory paper and presentation

Assessment


Theory (70%): NBTs: 1 x 1.5 hrs;


question (10 marks)

Presentation (15%): 1 x 15 min

Debate (15%): 1 x 15 min

OCAM Computation:

70% NBT + 15% Presentation + 15% Debate

Attendance at all three CATs is compulsory



Theory: 80%

1 paper: 2 hrs; 20 MCQs (20 marks), 03

SEQs (60 marks) and 01 Essay Question

(20 marks)


Presentation: 20% - 15 mins


1. Ludden, M. (2002 or latest edition). Effective communication skills: Essential skills for success in

work and life. Indianapolis, Ind: JIST Works.

2. Moss, B. (2008 or latest edition). Communication skills for health and social care. Los Angeles:

SAGE.

15


Course Code MDE3208

Course Title Refresher Course for Medical Laboratory Technologists

Credit value 02

Core/Optional Optional (Compulsory for Lateral Entrants)

Prerequisites None


38 hrs

(19 Sessions)

- - 58 hrs

(Sessions [52hrs) +

Online [08 hrs]

02 hrs

(2 CATs x 1hr)

100 hrs

Course Aim/s. ● To refresh the existing knowledge in the field of medical laboratory sciences

Programme

Learning Outcome

(PLO) addressed by

course

● PLO 01: Academic Expertise

Course Learning

Outcomes (CLO) The students should be able to: ● CLO 1: define the key terms related to medical laboratory sciences (PLO 01) ● CLO 2: describe basic chemical principles and metabolism of major biomolecules (PLO 01). ● CLO 3: recall basic theoretical knowledge in the main aspects of medical laboratory sciences

(PLO 01). ● CLO 4: outline the basic laboratory processes (PLO 01).


topics)

● Introduction to medical laboratory – Introduction to medical laboratory, Laboratory

equipment and instrumentation ● Basic chemistry – Chemical reactions ● Haematology – Specimen collection and handling in haematology, Changes of blood cells in

diseases, Routine haematological tests, Haemostasis. ● Medical Bacteriology – General Bacteriology, Control of bacteria and laboratory safety,

Culture methods and enumeration of bacteria, Medical important bacteria and their

identification ● Clinical Biochemistry - Major biomolecules of the body and their metabolism, Cellular

Energy metabolism ● Human Anatomy – Cells, tissues and organization of the human body, Introduction to

human anatomy ● Medical Parasitology – Medically important parasites, Laboratory techniques in medical

parasitology ● Laboratory Safety and Occupational Health - Hazards in Laboratory and safety measures,

Safe handling in chemicals

Teaching Learning

methods

● Self- learning: Course material online (19 Sessions), Online components ● Continuous assessments: 2 NBTs ● Final examination: Theory paper (online)

Assessment

strategy Overall CA Mark (OCAM): - 40% Final Assessment: 60%

Theory (100%): NBTs: 2 x 1hr (online); 25 MCQs (100

marks)

OCAM Computation:




Theory: 100%

1 paper: 2 hrs (online); 50 MCQs (100

marks)



1. Cheesbrough, M. (2006 or latest edition). District laboratory practice in tropical countries: Part 1




16


Course Code BSU4230

Course Title Basic Statistics

Credit value 02

Core/Optional Core

Prerequisites None


28 hrs

(14 Sessions)

6 hrs

(3 DS)

- 64 hrs

(Sessions [42 hrs] + online


readings [70 hrs])

2 hrs

(2 CATs x 1hr)

100 hrs

Course Aim/s. ● The main aim of the course is to provide the basic knowledge of sampling, data handling and

analysis of data using statistical methods

PLOs addressed by

course

● PLO1: Academic Expertise

● PLO5: Creativity and Problem Solving

● PLO7: Information and Data Management Skills

Course Learning

Outcomes (CLO)

The students should be able to: ● CLO1: Discuss statistical terminology, correct methods of data collection and errors that can

occur during analysis (PLO1)

● CLO2: Evaluate different data displays available for the different types of data (PLO1)

● CLO3: Select the most appropriate method of sampling suitable for the type of research

conducted (PLO7)

● CLO4: Analyze sample sizes and workout suitable samples for a given population using

different sampling techniques (PLO7, 5)

Content

(Main topics, sub

topics)

● Introduction to Health Statistics: Classification of research – pilot study, case study, clinical

trial, observations and experimental studies, terminology in medical research

● Summarizing data: Central tendency (mean, median, mode), dispersion (variance, standard

deviation, inter-quartile range)

● Normal distribution and Probability statistics: normal distribution, standard normal

distribution, Rules of probability, probability distribution,

● Qualitative & quantitative research: classification of variables, scale of measurement

● Presentation and qualitative data: Diagrams and graphs of qualitative data

● Presentation and quantitative data: graphical representation and quantitative data

● Errors in studies: random variation, bias, sampling error, missing values, non-sampling

errors

● Sampling methods: Probability sampling (random sampling), non-probability sampling.

● Populations and sampling: Populations and sample “parameters & statistics”, probability

sampling methods and non-probability sampling methods.

● Inference of means and proportions: Distribution of mean, standard error, confidence

intervals, point estimate and interval estimates.

● Measures of morbidity and mortality, fertility and Survival analysis: fertility, morbidity,

mortality, cohort life tables

● Descriptive statistics in medical research: retrospective, prospective studies, cohorts, case

control studies, cross sectional studies, concepts in epidemiology/health research

● Diagnostic tests and clinical trials

● Research designs in Health Sciences – Research designs, quantitative and qualitative

research methods

Teaching Learning

methods

● Self- learning: Course material in print (print), Online components, Recommended readings


● Continuous assessments: NBTs

● Final examination: 1 theory paper

Assessment strategy Overall Continuous Assessment Mark (OCAM): 40% Final Examination: 60%

17

Theory (100%): NBTs: 2 x 1hr; 10 MCQs (20 marks), 2

SEQs (80 marks)

OCAM Computation:




Theory: 100%

1 paper - 2 hrs (4 EQs) (100 marks)


Recommended

Readings:

1. Daniel, W. W. (2013). Biostatistics: A foundation for analysis in the health sciences. 10th Edition.

Hoboken, NJ, John Wiley & Sons, Inc. ISBN-13: 978-1118302798

2. Campbell, M. J., Machin, D. & Walters, S. J. (2007) Medical Statistics: A Textbook for the Health

Sciences. 4th Edition. West Sussex, England, John Wiley & Sons, Inc. ISBN:978-0-470-02519- 2

3. Kirkwood, B. R. & Sterne, J. A. C. (2003) Essential Medical Statistics. 2nd Edition. Cornwall, UK,

Blackwell Science Inc. ISBN:978-0-86542-871- 3

4. Daly, L. E. & Bourke, G. J (2000) Interpretation and uses of medical statistics. 5th Edition.

Massachusetts, USA, Blackwell Science Inc. ISBN: 978-0-632-04763-5

18


Course Code MDU4501

Course Title Haematology II

Credit value 05

Core/Optional Core

Prerequisites None


Learning

Assessment Total

62 hrs

(31 Sessions)

12 hrs

(6 DSs)

36 hrs

(6 days Lab)

137 hrs

(Sessions [99 hrs] +


Online [08 hrs] +

Recommended

readings [12 hrs])

03 hrs

(1 CAT x 1.5

hrs) + (1

Practical test

1.5 hrs)

250 hrs

Course Aim/s. ● To provide basic knowledge on red cell and platelet disorders, test principles and the

application of laboratory investigations in diagnosis of these disorders. ● To provide necessary theoretical knowledge and practical skills in activities related to blood

transfusion.

PLOs addressed by

course

● PLO 01: Academic Expertise ● PLO 02: Practical Competence ● PLO 05: Creativity and Problem Solving ● PLO 07 Information and Data Management Skills

Course Learning

Outcomes (CLO) The students should be able to: ● CLO 01: Discuss the pathology behind red cell disorders and platelet disorders. (PLO 01) ● CLO 02: Perform necessary laboratory investigations for the diagnosis of red cell and

platelet disorders (PLO 02) ● CLO 03: Critically evaluate and compare test results and other relevant information in red

cell and platelet disorders. (PLO07) ● CLO 04: Identify source of errors in hematological investigations and preventive actions

(PLO05) ● CLO 05: Explain the major and minor blood group systems with their clinical importance.

(PLO 01) ● CLO 06: Discuss the preparation and storage of blood components in blood banking and

blood transfusion (PLO 01) ● CLO 07: Perform different types of pre-transfusion testing to confirm the compatibility

and quality of the blood (PLO 02)


topics)

● Disorders of Haemoglobin - Structure and functions of Haemoglobin,

Haemoglobinopathies, Thalassemia ● Anaemia – Introduction to anaemia, Haemolytic anaemia, Anaemia due to cellular

defects, Anaemia due to enzyme defects, Anaemia due to Nutritional deficiencies,

Anaemia of chronic diseases, Red cell aplasia and hypoplasia ● Platelet disorders - Hereditary Platelet Disorders, Acquired Platelet Disorders, Increased

Destruction or Consumption of Platelets, Primary and secondary thrombocytosis, ● Introduction to blood transfusion - Blood group systems, Biochemical properties and

characteristics of blood group antigens and antibodies, Identification of natural and

Immune antibodies ● Blood collection, processing and component preparation - Donor selection, Blood

collection, Blood components, Storage of blood and components. ● Pre-transfusion testing - Blood groups, Compatibility testing- ABO grouping and Rh

typing, Antibody screening, Methods of cross matching, ABO and Rh blood group

discrepancies, Assuring quality in blood and blood products. ● Adverse effects of blood transfusion- Hemolytic transfusion reactions, Non-hemolytic

transfusion reactions, Transfusion transmitted infections, Other immediate and delayed

adverse effects.

Teaching Learning

methods ● Self- learning: Course material online (31 Sessions), Online components,






19

Assessment


Theory (50%): NBT: 1 x 1.5hrs;




OCAM Computation:






Theory: 100%

1 paper – 3hrs; 30 MCQs (30 marks), 04


(30 marks)





2. Hoffbrand, A. V., Moss, P. A. H., & Pettit, J. E. (2006 or latest edition). Essential haematology.

Malden, Mass: Blackwell Pub.

3. Contreras, M. (2009 or latest edition). ABC of transfusion. Chichester, UK: Wiley-Blackwell

Pub.

20


Course Code MDU4302

Course Title Diagnostic Bacteriology

Credit value 03

Core/Optional Core

Prerequisites None


Learning

Assessment Total

30 hrs

(15 Sessions)

06 hrs

(3 DSs)

30 hrs

(5 days Lab)

74 hrs



Online [08 hrs] +

Recommended

readings [06 hrs])

10 hrs

(1 CAT x 1.5 hrs)

+ (1 Practical test

8.5 hrs)

150 hrs

Course Aim/s. ● To impart comprehensive theoretical knowledge in laboratory diagnosis of human

infections caused by bacteria and to foster practical competencies that required to pursue

a career in a medical microbiology laboratory

PLOs addressed by

course

● PLO 01: Academic Expertise ● PLO 02: Practical Competence ● PLO 03: Effective Communication and Networking ● PLO 05: Creativity and Problem Solving ● PLO 07: Information and Data Management Skills

Course Learning

Outcomes (CLO) The students should be able to: ● CLO 01: Describe scientific basis of human infectious diseases caused by bacteria,

aetiology, epidemiology , prevention and control of infectious diseases (PLO 01) ● CLO 02: Classify different classes of antibiotic and compare the basic mechanisms of

mode of action of different classes of antibiotics and the bacterial resistance mechanisms

(PLO 01) ● CLO 04: Explain specimen collection guidelines and evaluate the acceptability of

specimens for potential pathogens (PLO 1, PLO 05) ● CLO 03: Investigate the clinical samples to identify aetiological agents, critically evaluate,

interpret and report laboratory results appropriately (PLO 02, PLO 05, PLO 07) ● CLO 04: Perform antibiotic susceptibility testing to determine the effective antibiotic

regimen, interpret and report results (PLO 02, PLO 05, PLO 07) ● CLO 04: communicate information clearly both verbally and in writing (PLO 03) ● CLO 05: Apply the QA and QC concepts to identify errors, to take corrective actions and

to produce accurate and precise laboratory results (PLO 01, PLO 02, PLO 07, CLO 05)


topics)

● Bacteriology of infective diseases- Urinary tract infections, Bloodstream infections,

Meningitis and other CNS infections, Musculo-skeletal infections, Skin and soft tissue

infections, Respiratory tract infections, Genital tract infections, Gastrointestinal tract

infections, Diagnosis of tuberculosis ● Antibiotic agents – Classification of antibiotic agents, Mechanisms of action, Resistance

mechanisms, Laboratory detection of antibiotic resistance, Antibiotic sensitivity testing

methods, Quality Control (QC) and Quality Assurance (QA) in Microbiology

Teaching Learning

methods



Assessment






OCAM Computation:






Theory: 100%

1 paper – 3hrs; 30 MCQs (30 marks),

04 SEQs (40 marks) and 02 Essay

Questions (30 marks)


21


1. Ash L. A. and Oriel T.C. A Guide to Laboratory procedure and Identification. American

Society of Clinical Pathologists. Chicago – Latest edition 2. Atlas R. Principles of Microbiology, Mosby Publishers – Latest edition 3. Cheesbrough Monica. Medical Laboratory Manual for Tropical Countries. Vol: 1 &11,

Butterworth- Heinmann Ltd. Oxford – More Advanced Edition 4. Isenberg, Henry D. (editor). Clinical Microbiology Procedures Handbook – Latest

edition 5. Laboratory Biosafety Manual. World Health Organization– Latest edition 6. World Health Organization Manual of Basic techniques for a Health laboratory. Geneva

– Latest edition 7. Thevanesam V., Laboratory manual in Microbiology, Latest edition, Sri Lanka college of

Microbiologists, World Health Organization. 8. Greenwood, D. (2012 or latest edition). Medical microbiology: A guide to microbial infections:

pathogenesis, immunity, laboratory diagnosis and control. Edinburgh: Churchill

Livingstone/Elsevier.

22


Course Code MDU4303

Course Title Clinical Biochemistry II

Credit value 03

Core/Optional Core

Prerequisites None


26hrs

(13 Sessions)

06 hrs

(3 DSs)

30hrs

(5 days Lab)

84 hrs

(Sessions [39hrs] +

Practical [15hrs] +

Online [14hrs] +

Recommended

readings [16 hrs])

04 hrs

(1 CAT x 1.5

hrs) + (1

Practical test

2.5 hrs)

150 hrs

Course Aim/s. ● To provide basic knowledge on biochemical aspects of blood and other body fluids, how they

change in different disease conditions and to provide opportunity to develop required

practical skills in performing biochemical investigations.

PLOs addressed by

course

● PLO 01: Academic Expertise ● PLO 02: Practical Competence ● PLO 05: Creativity and Problem Solving ● PLO 07: Information and Data Management Skills

Course Learning

Outcomes (CLO) The students should be able to: ● CLO 01: Explain the principles and perform biochemical investigations of blood and other

body fluids. (PLO 01, 02) ● CLO 02: Evaluate the results of biochemical investigations and comment on their disease

conditions. (PLO 07) ● CLO 03: Identify and minimize pre – analytical, analytical and post analytical errors. (PLO

05) ● CLO 04: Discuss the characteristics of common metabolic disorders. (POL 01) ● CLO 05: Analyse clinical specimens to identify main metabolic disorders. (PLO 02)


topics)

● Disorders of carbohydrate metabolism and laboratory diagnosis - Disorders of

carbohydrate metabolism, Diabetes Mellitus, Blood Glucose determination and diagnosis of

Diabetes, Complications of Diabetes and laboratory diagnosis. ● Disorders of Lipid metabolism and laboratory diagnosis – Disorders of Lipid and

Lipoprotein metabolism, Analysis of Lipids and Lipoproteins. ● Serum / Plasma Protein – Changes of protein levels in disorders, Estimation of serum

/Plasma proteins ● Other body fluids – Analysis of Cerebrospinal fluid (CSF), Analysis body cavity fluids, Stool

analysis ● Disorders of reproduction and laboratory diagnosis – Disorders of reproduction in male

and laboratory diagnosis, Disorders of reproduction in female and laboratory diagnosis

Teaching Learning

methods



Assessment






OCAM Computation:






Theory: 100%



(30 marks)


23


1. Burtis, C. A., Ashwood, E. R., Border, B., & Tietz, N. W. (2001 or latest edition). Tietz

fundamentals of clinical chemistry. Philadelphia: W.B. Saunders.



3. Varley, H., Gowenlock, A. H., McMurray, J. R., McLauchlan, D. M., & Varley, H. (1988 or

latest edition). Varley's practical clinical biochemistry. Boca Raton, Fla: CRC Press.

24

Semester and Level Semester II, Level 4

Course Code BSU4245

Course Title Human Physiology

Credit value 02

Core/ Optional Core

Prerequisites BSU3230(EL)

Hourly Breakdown Theory Practical Independent

Learning

Assessments Total

30 hrs

(15 sessions)

6 hrs

(3 DS)

6 hrs

(2 day x 3 hrs)

60 hrs

(Sessions [45 hrs] + Lab

[3 hrs] + online [8 hrs]

Recommended reading

[4 hrs])

3 hrs

(2 CATs x 1hr

+

1 PA x 1 hr)

105 hrs

Course Aims ● The main aim of the course is to provide a detailed understanding on the anatomy and

physiology of the human body.

Programme

Learning Outcomes

(PLO) addressed by

course

● PLO1: Knowledge and understanding

● PLO2: Practical competence

● PLO5: Creativity and problem solving

● PLO6: Information and data literacy

Course Learning

Outcomes (CLO)

At the completion of this course student will be able to:

● CLO1: Describe the development and organization of normal body structures (PLO1)

● CLO2: Describe the physiology of the organ systems and the conditions necessary to

maintain homeostasis (PLO1, 2)

● CLO3: Apply knowledge of human anatomy and physiology in clinical practice

(PLO1, 2, 5, 6)

Content

(Main topics, sub

topics)

Introduction to human anatomy and physiology, Basic biochemistry, Structure and

function of cells, Nervous system, Sensory organs, Muscle system, Endocrine system,

Blood and the heart, Blood vessels and lymphatic system, Immune system, Respiratory

system, Digestive system I, The alimentary canal

● Digestive system II, Accessory organs

● Urinary system

● Reproductive system

Teaching- Learning

methods

● Self- learning: course material (printed), Online components, Recommended readings

● Compulsory contact sessions: Laboratory classes - 2 days (anatomy: observe organs,

physiology: blood pressure, cardiac rhythm, vision, spirometry)

● Non-compulsory contact sessions: 3 Day schools

● Continuous Assessments: NBT I and NBT II


Assessment

Strategy

Overall Continuous Assessment Mark (OCAM): 40% Final Examination: 60%

Theory (80%): NBT: 2 x 1 hr;


Practical Assessment (20%) – 1 hr

OCAM Computation:

40% of NBT I + 40% of NBT II + 20% PA

Minimum 50% marks compulsory for PA



Final Evaluation:

Theory: 100%

1 paper - 2 hrs

20 MCQs (20 marks) +2 SEQs (40

marks) +2 Essay (40 marks)


Recommended

Reading

1. VanPutte, C. L., Redan, J., Russo, A. & Seeley, R. (2014). Seeley's anatomy & physiology.

11th Edition. McGraw-Hill. New York, U.S.A. ISBN: 9781259671142

2. Tortora, G. J., & Grabowski, S. R. (2000). Principles of anatomy and physiology. 14th

Edition. John Wiley & Sons. New York, U.S.A. ISBN:978-0-7637-3792-4

25

3. Waugh, A., Grant, A., & Ross, J. S. (2001). Ross and Wilson anatomy and physiology in

health and illness. Churchill Livingstone Elsevier. Edinburgh, Scotland ISBN: 978-0-

7020-3227-1

4. Saladin, K. S. (2014) Anatomy & Physiology: The Unity of Form and Function (Standalone

Book). 7th Edition. McGraw Hill. New York, U.S.A. ISBN: 978-0073403717

5. Barrett, K. E., Barman, S. M., Boitano, S. & Brooks, H. (2012) Ganong's Review of Medical

Physiology. 24th Edition. McGraw Hill. China. ISBN: 978-0071780032

https://www.amazon.com/Anatomy-Physiology-Unity-Function-Standalone/dp/0073403717/ref=sr_1_1?s=books&ie=UTF8&qid=1503644397&sr=1-1&keywords=Anatomy+And+Physiology













26


Course Code MDU4405

Course Title Work Based Training II

Credit value 04

Core/Optional Core

Prerequisites (MDU4406, MDU4303) CR


- 02 hrs

(1 DSs)

210 hrs

(35 days

training)

185 hrs

Lab training [105 hrs] +


hrs] Online [20 hrs]

Recommended

readings [25 hrs])

03 hrs

(2 Practical tests

x 1.5 hrs)

400 hrs

Course Aim/s. ● To provide hands on experience in performing biochemical and histopathological laboratory

procedures, supporting learner to develop competent, ethical and reflective professional

practice.

PLOs addressed by

course

● PLO 01: Academic Expertise ● PLO 02: Practical Competence ● PLO 03: Effective Communication and Networking ● PLO 04: Teamwork and Leadership ● PLO 05: Creativity and Problem Solving ● PLO 07: Information and Data Management Skills ● PLO 08: Ethical Professional Behaviour

Course Learning

Outcomes (CLO) Students should be able to: ● CLO 01: Perform routine biochemical tests and all histopathological tests assigned for

Medical Laboratory Scientists. (PLO 02) ● CLO 02: Evaluate the test results, compare them with the disease pathologies and comment

on the possible diagnosis. (PLO 05,07) ● CLO 03: Identify possible laboratory errors and develop protocols for quality improvement.

(PLO 05) ● CLO 04: Evaluate existing laboratory procedures and propose improvements (PLO 01, 05.

07) ● CLO 05: Interact with patients and health care professionals in providing effective patient care.

(PLO 03, 04) ● CLO 06: Demonstrate ability in working efficiently and effectively in different working

environments (PLO 09) ● CLO 07: Demonstrate professional and ethical behavior in the working environment (PLO 08)


topics)

● Histopathology ● Clinical Biochemistry

Teaching Learning

methods

● Self- learning: Online components, Recommended readings ● Compulsory contact sessions: Laboratory training - 35 days x 6hrs ● Non-compulsory contact sessions – 1 Day school ● Continuous assessments: 2 Practical tests (PT) ● Final examination: 1 Theory paper, Reflective journal and Viva voce

Assessment


Practical (100%): Practical tests – 2 x 1.5 hrs

OCAM Computation:

50 % PT1 mark + 50 % PT2 mark

Attendance at both PTs & training is

compulsory



only for 2 years





1. Bancroft, J. D., Cook, H. C., & Stirling, R. W. (1994 or latest edition). Manual of histological

techniques and their diagnostic application. Edinburgh: Churchill Livingstone.

2. Sheehan, D. C., & Hrapchak, B. B. (1987 or latest edition). Theory and practice of histotechnology.

Columbus, Ohio: Battelle Press.



4. Varley, H., Gowenlock, A. H., McMurray, J. R., McLauchlan, D. M., & Varley, H. (1988 or latest

edition). Varley's practical clinical biochemistry. Boca Raton, Fla: CRC Press.

27


Course Code MDU4406

Course Title Histopathology

Credit value 04

Core/Optional Core

Prerequisites None


48 hrs

(24 Sessions)

08 hrs

(4 DSs)

36 hrs

(6 days Lab)

104 hrs


Practical [18 hrs] + Online


readings [8 hrs)

04 hrs

(1 CAT x 1.5

hrs) + + (1

Practical test 2.5

hrs)

200 hrs

Course Aim/s. ● To provide adequate knowledge on microanatomy of tissues, their changes in different

pathological conditions and histopathological procedure of laboratory identification of these

changes. ● To provide opportunity to develop laboratory skills in routine and special histopathological

techniques.

PLOs addressed by

course


Course Learning

Outcomes (CLO) Students should be able to: ● CLO 01: Identify and illustrate microscopic structure of organs, tissues and cells of human body

systems and their changes in pathological conditions. (PLO 01) ● CLO 02: Describe the principles of histopathological procedures (PLO 01) ● CLO 03: Perform all histopathological techniques assigned for Medical Laboratory Scientists.

(PLO 02, 05) ● CLO 04: Operate, troubleshoot and maintain equipment in histopathology laboratories. (PLO

01, 02, 05) ● CLO 05: Discuss the importance, weaknesses and possible improvements in quality assurance

procedures in histopathology (PLO 01, 05, 07) ● CLO 06: Explain the principles of immunohistochemical methods and their application in

histopathology laboratories. (PLO 01)


topics)

● Introduction to histopathology: Introduction to histopathology, Specimen collection,

handling and fixation.

● Preparation of specimens: Handling small specimens, Decalcification

● Specimen Processing and tissue sectioning: Tissue processing & embedding I, Tissue

processing and embedding II, Tissue sectioning

● Staining: Introduction to staining, Routine stains, Special stains

● Microanatomy: Histology of epithelial tissues and connective tissues, Histology of bone,

cartilage & muscle, Histology of cardiovascular system, Histology of urinary system, Histology

of male & female reproductive system, Histology of liver, Histology of gastrointestinal tract &

associated organs, Histology of respiratory system, Histology of reticulo-endothelial system,

lymphoid tissue, spleen & lymph nodes, Histology of nervous system

● Immunohistochemistry: Introduction to Immunohistochemistry, Immunohistochemical

methods

● Quality assurance in histopathology: Quality assurance in histopathology, Safety in

Histopathology

Teaching Learning


readings



● Continuous assessments: 1 NBT + Practical Test (PT)


Overall CA Mark (OCAM): 40% Final Assessment: 60%

28

Assessment

strategy Theory (50%): NBT: 1 x 1.5hrs ;




OCAM Computation:






Theory: 100%

1 paper – 3hrs; 30 MCQs (30 marks), 04 SEQs

(40 marks) and 02 Essay Questions (30 marks)



1. Bancroft, J. D., & Gamble, M. (2002 or latest edition). Theory and practice of histological techniques.

London: Churchill Livingstone.

2. Cuello, A. C. (1983 or latest edition). Immunohistochemistry. Chichester, West Sussex: Wiley.

29

Semester and Level Semester – Level 04

Course Code MDU4307

Course Title Virology & Mycology

Credit value 03

Core/Optional Core

Prerequisites None


36 hrs

(18 Sessions)

06 hrs

(3 DSs)

24 hrs

(4 days Lab)

80 hrs




readings [8 hrs])

04 hrs

(1 CAT x 1.5

hrs) + (1

Practical test x

2.5 hrs)

150 hrs

Course Aim/s. ● To empower the learner with knowledge and skills in virology and mycology while supporting

learner to develop competent, ethical and quality practice.

PLOs addressed by

course


Course Learning

Outcomes (CLO) Students should be able to: ● CLO 01: Define key terms used in virology and mycology. (PLO 01) ● CLO 02: Outline the classification of viruses and fungi and explain the basis. (PLO 01) ● CLO 03: Explain key structural and functional properties of viruses and fungi, which promotes

their transmission and pathogenesis. (PLO 01) ● CLO 04: Explain the principles and perform laboratory techniques in identification of viruses

and fungi. (PLO 01, 02) ● CLO 05: Evaluate the quality control procedures and safety precautions in virology and

mycology laboratories and comment on necessary improvements. (PLO 01,07,05)


topics)

● Virology - Introduction to Virology, Classification of viruses, Diagnosis treatment and control

of viruses, Viral Enteric Diseases, Viral Hepatitis, Viral Respiratory diseases, Viral infections of

the skin- skin rashes, Viral Haemorrhagic Fevers, Neurological diseases of viral origin, Genital

tract infections of viral origin, Other viral infections.

● Mycology – Overview of Medical Mycology, Fungal disease in human, Collection, transport

and storage of specimens, Superficial mycoses, Subcutaneous mycoses, Agents of

Hyalohyphomycosis, Yeast, Zygomycetes, Agents of phaeohyphomycosis, Non-culture

methods of identification of fungi, Antifungals and Antifungal sensitivity test

Teaching Learning


readings





Assessment






OCAM Computation:






Theory: 100%



(30 marks)



1. Brooks, G. F., Butel, J. S., Morse, S. A., &Jawetz, E. (2004 or latest edition). Jawetz, Melnick,

&Adelberg's medical microbiology. New York, N.Y: Lange Medical Books/McGraw-Hill, Medical

Pub. Division.

2. Goering, R. V., & Mims, C. A. (2008 or latest edition). Mims' medical microbiology. Philadelphia,

PA: Mosby Elsevier.

3. Fenner, F., & White, D. O. (1986 or latest edition). Medical virology. Orlando: Academic Press.

4. Deacon, J. W., & Deacon, J. W. (1997 or latest edition). Modern mycology. Oxford England:

Blackwell Science.

30


Course Code MDU4208

Course Title Ethics & Professional Development

Credit value 02

Core/Optional Core

Prerequisites None


28 hrs

(14 Sessions)

06 hrs

(3 DSs)

-

64 hrs


Online [12 hrs] +

Recommended

readings [10 hrs])

2hrs

(2 CATs x 1hr)

100 hrs

Course Aim/s. ● To provide fundamental theories of ethics and professionalism, enabling learner to develop

ability to recognize, articulate and apply code of ethics and professional competencies in

various academic, professional, social, or personal contexts.

PLOs addressed by

course

● PLO 01: Academic Expertise ● PLO 03: Effective Communication and Networking ● PLO 05: Creativity and Problem Solving ● PLO 07: Information and Data Management Skills ● PLO 08: Ethical Professional Behaviour ● PLO 09: Self-management and Lifelong Learning

Course Learning

Outcomes (CLO) Students should be able to: ● CLO 01: Demonstrate ethical and professional behavior (PLO 08) ● CLO 02: Demonstrate competency in communicating with people at different levels.

(PLO03) ● CLO 03Demonstrate ability in developing productive relationships with people at all

levels (PLO 03) ● CLO 04: Identify ethical issues in the working environment, describe the current methods

of addressing them and propose improvements. (PLO 01, 05, 07, 08) ● CLO 05: Evaluate the effectiveness of current policies and procedures and propose

necessary improvements. (PLO 01, 05, 07) ● CLO 06: Demonstrate interest and motivation in lifelong learning and professional

development. (PLO 09)


topics)

● Medical ethics and legal aspect – Introduction to Ethics, professional secrecy, Ethics in

clinical trials, Ethics in animal studies, Ethics in handling of clinical specimens and other

biological specimens, Ethics in disease screening. ● Professional development - Team work and Leadership, Attitudes, Time management,

Administration, Professional communication and presentation skills, Professional

behavior, Concept of lifelong learning and continuing professional development,

professional practice.

Teaching Learning

methods


readings ● Non-compulsory contact sessions – 3 Day schools ● Continuous assessments: 2 NBTs ● Final examination: 1 Theory paper, Viva voce and oral presentation

Assessment


Theory (100%): NBTs: 2 x 1 hr;

10 MCQs (10 marks) + 02 SEQs (80 marks) +

01 Essay Question (10 marks)

OCAM Computation:




only for 2 years

Theory: 80%


(60 marks) and 01 Essay Question (20 marks)


Other: 20%

Viva voce (70%)- 10 min

Oral presentation (30%) – 10 min

31


1. Tipton, D., (2007 or latest edition). Personal and Professional Growth for Health Care

Professionals.

2. Arora, DR, & Arora, B. (2007 or latest edition). Ethics in laboratory medicine. (Indian Journal

of Medical Microbiology (ISSN: 0255-0857) Vol 25 Num 3.) Medknow Publications on

behalf of Indian Association of Medical Microbiology.

3. Godkin, D., Markwell, H., & Ontario. (2003 or latest edition). The duty to care of healthcare

professionals: Ethical issues and guidelines for policy development. Toronto, Ont.: Ontario

Ministry of Health and Long-Term Care.

32


Course Code MDU4209

Course Title General Pathology

Credit value 02

Core/Optional Core

Prerequisites None


Independent

Learning

Assessment Total

26 hrs

(13 Sessions)

06 hrs

(3 DSs)

-

66 hrs


Online [14 hrs] +

Recommended

readings [13 hrs])

02 hrs

(2 CATs x 1hr)

100hrs

Course Aim/s. ● To provide basic knowledge on pathological processes and to discuss the involvement

of these processes in disease pathogenesis.

PLOs addressed by

course

● PLO 01: Academic Expertise ● PLO 03: Effective Communication and Networking

Course Learning

Outcomes (CLO) Students should be able to: ● CLO 01: Describe disease processes due to pathological alterations at tissue level. (PLO

01) ● CLO 02: Utilize appropriate pathologic terminology to properly explain the cellular and

tissue changes. (PLO 01, 03) ● CLO 03: Describe basic patterns of changes in neoplastic cells. (PLO 01)


topics)

● Cell injury and tissue response to injury - Cell injury & necrosis, Cellular and tissue

response to damage, Cellular adaptations to injury. ● Inflammation & repair - Acute inflammation, Chronic inflammation, Healing & repair ● Tissue changes in vascular injury- Thrombosis and embolism, Ischaemia&

congestion, Infarction & gangrene ● Neoplasia - Basic concepts of neoplasia, Molecular basis of carcinogenesis, Cellular

changes in neoplastic cells, Effects of Neoplasms

Teaching Learning

methods

● Self- learning: Course material in print (13 Sessions), Online components,

Recommended readings ● Non-compulsory contact sessions – 3 Day schools ● Continuous assessments: 2 NBTs





OCAM Computation:




only for 2 years

Theory: 100%





1. Reid, R., Roberts, F., & Macfarlane, P. S. (2005 or latest edition). Pathology illustrated.

Edinburgh: Elsevier/Churchill Livingstone.

2. Cotran, R. S., Kumar, V., Collins, T., & Robbins, S. L. (1999 or latest edition). Robbins

pathologic basis of disease.Philadeolphia: Saunders.

33

Semester and Level Semester II - Level 05

Course Code BSU5230

Course Title Applied Statistics

Credit value 02

Core/Optional Core

Prerequisites BSU4430


20 hrs

(10 Sessions)

4 hrs

(2 DS)

6 hrs

(1 Day x 6hrs)

67 hrs


Practical [9 hrs] +

online [8 hrs]

Recommended

readings [20 hrs])

3 hrs

(2 CATs x 1hr

+ 1 PA x 1 hr)

100 hrs

Course Aim/s. ● To provide an understanding on the concepts and applications of statistical methods.

● To develop knowledge, attitudes and skills required for evidence based medical laboratory

science.

● To empower students to communicate statistical practices and methodologies.

● To develop IT, analytical and critical thinking skills

PLOs addressed by

course

● PLO1: Academic Expertise

● PLO2: Practical Competence

● PLO5: Creativity and Problem Solving

● PLO7: Information and Data Management Skills

Course Learning

Outcomes (CLO)

The students should be able to: ● CLO1: Appraise parametric, non-parametric, qualitative and quantitative statistical methods

(PLO1)

● CLO2: Explain the relevance and use of statistics (PLO1)

● CLO3: Apply appropriate statistical methods to suit research objectives (PLO1, 7)

● CLO4: Demonstrate competences in execution and interpretation of core statistical

techniques used by health care professionals (PLO2, 5, 7)

● CLO5: Interpret and produce graphical and numerical summaries of data (PLO2)

Content

(Main topics, sub

topics)

● Statistical inference: point estimation and interval estimation

● Hypothesis testing: Null hypothesis and alternate hypothesis, t-distribution, type I and type

II errors

● t-test: one sample, two independent samples and two dependent samples

● paired t- test: one sample mean, one sample proportion, two independent sample mean

● Chi-squared test: application of chi-squared test, degrees of freedom, rules in calculating

chi-squared values

● Correlation and linear regression: identify dependent and independent variable, interpret

scatter plot, interpret regression

● Analysis of variance (ANOVA): one-way ANOVA

● Computer Based Statistical analysis – SPSS I, SPSS II, Other statistical software

● Selecting appropriate statistical tests

● Non-parametric tests: Wilcoxon signed-rank test, Wilcoxon rank-sum test, Spearmen’s rank

correlation

Teaching Learning

methods

● Self- learning: Course material in print (print), Online components, Recommended readings

● Compulsory contact sessions: Laboratory classes - 3 days (data entry, analysis of data on

Excel, graphical summary of data, Software package, analysis of data)


● Continuous assessments: NBTs


Overall Continuous Assessment Mark (OCAM): 40% Final Examination: 60%

34

Assessment

strategy

Theory (80%): NBTs: - 1 hr x 2


Practical (20%) – 1 hr

OCAM computation:

40% of NBT I + 40% of NBT II + 20% PA

Minimum 50% marks compulsory for PA

Minimum OCAM of 40% is required to be eligible for the

Final exam; Eligibility valid only for 2 years

Final Evaluation:

Theory: 100%

1 paper - 2 hrs 4 EQs (100 marks)


Recommended

Readings:

1. Daniel, W. W. (2013). Biostatistics: A foundation for analysis in the health sciences. 10th Edition.

Hoboken, NJ, John Wiley & Sons, Inc. ISBN-13: 978-1118302798

2. Campbell, M. J., Machin, D. & Walters, S. J. (2007) Medical Statistics: A Textbook for the Health

Sciences. 4th Edition. West Sussex, England, John Wiley & Sons, Inc. ISBN:978-0-470-02519- 2

3. Kirkwood, B. R. & Sterne, J. A. C. (2003) Essential Medical Statistics. 2nd Edition. Cornwall, UK,

Blackwell Science Inc. ISBN:978-0-86542-871- 3

4. Daly, L. E. & Bourke, G. J (2000) Interpretation and uses of medical statistics. 5th Edition.

Massachusetts, USA, Blackwell Science Inc. ISBN: 978-0-632-04763-5

5. Zar, J. H. (2010). Biostatistical analysis. 5th Edition. Upper Saddle River, NJ. Prentice-

Hall/Pearson Education Ltd. ISBN:978-1-292-02404-2

6. Triola, M. M., & Triola, M. F. (2014). Biostatistics for the biological and health sciences. 1st

Edition. Pearson new international edition. Boston, USA. Pearson Education Ltd. ISBN: 978-

1-292-03964-0

35

Semester and Level Semester 1 - Level 5

Course Code MDU5401

Course Title Advanced Haematology

Credit value 04

Core/Optional Core

Prerequisites None

Hourly breakdown Theory Practical hours


hours

58 hrs

(29 Sessions)

10 hrs

(5 DSs)

24 hrs

(4 days Lab)

109 hrs



Online [03 hrs] +

Recommended

readings [04 hrs])

04 hrs

(1 CAT x

1.5hrs) + +

(1 Practical

test 2.5 hrs)

205 hrs

Course Aim/s. ● To provide knowledge on haematological disorders and their laboratory diagnosis. ● To provide necessary practice in performing relevant laboratory tests and basic knowledge

on treatment modalities such as stem cell transplantation.

PLOs addressed by

course


Course Learning

Outcomes (CLO) Students should be able to, ● CLO 01: Describe pathophysiology and laboratory identification methods of main

haematological disorders (PLO 01) ● CLO 02: Perform haematological investigations adhering to standard procedures,

interpret the results and comment on possible disease conditions (PLO 01, 02, 05, 07) ● CLO 03: Explain the disease pathogenesis, classifications and laboratory identification of

haematological malignancies. (PLO 01) ● CLO 04: Operate, troubleshoot and maintain all the automated instrument used in the

haematology laboratory. (PLO 01, 02, 05)


topics)

● Bone marrow disorders - Pancytopenia and Aplastic Anemia, Congenital Bone marrow

disorders ● Defects in hemostasis- Hereditary bleeding disorders, acquired bleeding disorders,

Bleeding disorders due to vascular abnormalities, Thrombosis and thrombophilia,

Antiphospholipid syndrome. ● White blood cell disorders - Granulocyte dysfunction disorders, Granulocytopenia,

Lymphopenia and lymphocyte dysfunction syndromes, Other white cells disorders. ● Haematological Malignancies - Classification of human hematopoietic neoplasms,

Myeloproliferative disorders, Essential thrombocythemia, Acute myelogenous leukemia,

Chronic myelogenous leukemia, Myelodysplastic syndrome. Lymphoproliferative

disorders (Lymphoid disorders and lymphoma), Chronic lymphocytic leukemia/Small

Lymphocytic Lymphoma, Multiple myeloma ● Peripheral blood stem cell transplantation - Peripheral Blood Stem Cell Transplantation

(PBSCT), Pluripotent stem cells and harvesting, Analysis, Processing and storage of stem

cells ● Immunomarkers in haematology - Cell surface and intracellular antigens in

haematological diseases, Flowcytometry, Haematological cytochemistry ● Laboratory haematology - Ref range calculation of reference ranges, Automation in

Haematology, Quality control in haematology

Teaching Learning

methods


Recommended readings ● Compulsory contact sessions: Laboratory classes - 04 days x 6hrs

Non-compulsory contact sessions – 5 Day schools ● Continuous assessments: 1 NBT + Practical Test (PT) ● Final examination: 1 Theory paper

Assessment






OCAM Computation:

Theory: 100%



(30 marks)


36





eligible for the Final exam; Eligibility valid only

for 2 years




2. Linch, D. C., Yates, A. P., & Watts, M. J. (1996). Haematology. Edinburgh: Churchill

Livingstone.

3. Cheesbrough, M. (2006 or latest edition). District laboratory practice in tropical countries:

Part 2. Cambridge: Cambridge University Press.

37


Course Code MDU5202

Course Title Vector Borne Diseases

Credit value 02

Core/Optional Core

Prerequisites None


Learning

Assessment Total

26 hrs

(13 Sessions)

6 hrs

(3 DSs)

12 hrs

(2 days Lab)

60 hrs

(Sessions [45hrs] +

Practical [06hrs] +

Online [03 hrs] +

Recommended

readings [06 hrs])

02 hrs

(1 CAT x 1 hr) +

+ (1 Practical

test 1 hr)

106 hrs

Course Aim/s. ● To provide a comprehensive knowledge on vector borne diseases in tropical and subtropical

region with respect to disease diagnosis, geographical distribution of diseases, arthropod

vectors, vector-pathogen interactions, vector biology & bionomics, treatment and control of

diseases.

PLOs addressed by

course

● PLO 01: Academic Expertise

● PLO 02: Practical Competence

● PLO 05: Creativity and Problem Solving

● PLO 07: Information and Data Management Skills

Course Learning

Outcomes (CLO) Students should be able to:

● CLO 01: Explain the prevalence of vector borne diseases with respect to their diagnosis,

distribution, diseases transmission, vectors, vector bionomics, treatment of the disease and

vector control (PLO 01)

● CLO 02: Apply basic knowledge in morphology of vectors in identifying and classifying of

vectors and parasites within vectors. (PLO 01, PLO2)

● CLO 03: Evaluate vector control measures and disease prevention strategies in current

practice and propose new strategies. (PLO 01, PLO 02)

● CLO 04: Document current scientific information on vector borne diseases in the form of

literature surveys, review reports, field site visit reports, group project reports etc. (PLO 01,

PLO 02, PLO 05, PLO 07)


topics)

● Introduction to vector borne diseases

Disease diagnosis, their distribution, vectors, vector-pathogen disease transmission cycles,

vector bionomics, treatment and control of following diseases. ● Mosquito borne diseases - Malaria, Filariasis, Dengue, Japanese Encephalitis, Zika ● Fly borne diseases – Leishmaniasis, Onchocerciasis, African Trypanosomiasis and other fly

borne diseases ● Tick and mite borne diseases ● Bugs and lice borne diseases and flea borne diseases

Teaching Learning

methods ● Self- learning: Course material in print (15 Sessions), Online components, Recommended

readings

● Compulsory contact sessions: Laboratory classes - 02 days x 6 hrs


● Continuous assessments: 1NBTs + Practical Test (PT)


Theory (50%): NBT: 1 x 1 hr;


Question (10 marks)

Practical (50%): Practical test – 1 hr

OCAM Computation:


Minimum 50 marks compulsory for PT




Theory: 100%


SEQs (60 marks) and 01 Essay

Question (20 marks)



1. Goddard, J. (2000). Infectious diseases and arthropods. Totowa, N.J.: Humana Press.

2. Goddard, J. (2007). Physician's guide to arthropods of medical importance. Boca Raton: CRC

Press.

https://en.wikipedia.org/wiki/Onchocerciasis

38

3. Eldridge, B., & Edman, J. (2004) Medical Entomology; A Textbook on Public Health and

Veterinary Problems Caused by Arthropods. Springer Press.

39


Course Code MDU5303

Course Title Immunology & Serology

Credit value 03

Core/Optional Core

Prerequisites None


40hrs

(20 Sessions)

08 hrs

(4 DSs)

12hrs

(2 days Lab)

87 hrs

(Sessions [60hrs] +

Practical [06hrs] +

Online [10 hrs] +

Recommended

readings [11 hrs])

03 hrs

(1 CAT x

1.5hrs) + (1

Practical

test 1.5 hrs)

150hrs

Course Aim/s. ● To provide knowledge on the immune system, immunological disorders and their

laboratory identification procedures.

● To provide necessary skills in performing immunoassays and laboratory investigations

in assessing immunity.

PLOs addressed by

course ● PLO 01: Academic Expertise

● PLO 02: Practical Competence

● PLO 05: Creativity and Problem Solving

● PLO 07: Information and Data Management Skills

Course Learning

Outcomes (CLO) Students should be able to:

● CLO 01: Describe cellular and humoral mechanisms of immunity in health and disease.

(PLO 01)

● CLO 02: Explain the principles and perform immunoassays and investigations in

assessing immunity. (PLO 01, 02)

● CLO 03: Interpret the laboratory findings and comment on possible disease conditions.

(PLO 01, 05, 07)

● CLO 04: Evaluate the quality control process of immunoassays and propose

improvements. (PLO 01, 02, 05)


topics)

● Overview of the immune system - Introduction to immunity, Cells and organs of

immune system

● Less specific host defense - Innate immunity, The complement system, Cytokines and

chemokines

● Acquired specific immunity- Humoral and cell mediated immunity, Major

histocompatability complex, B cells and T cells, Antibody generation and function

● Immune system health and diseases - Immunity and infection, Hypersensitive

reactions, Tolerance and autoimmunity, Immune deficiency, Primary/secondary

response to antigens and vaccines, Transplantation immunology, Cancer immunology

● Practical aspects of immunology – Antigen -Antibody reactions and immunoassays,

Monoclonal antibodies: production, purification and uses, Isolation of

immunoglobulins and cells

Teaching Learning

methods ● Self- learning: Course material online (20 Sessions), Online components,






Assessment






OCAM Computation:






Theory: 100%

1 paper – 3hrs; 30 MCQs (30

marks), 04 SEQs (40 marks) and 02

Essay Questions (30 marks)


40


1. Roitt, I. M., Brostoff, J., & Male, D. K. (latest edition). Immunology. London: Mosby.

2. Carpenter, P. L. (1965 or latest edition). Immunology and serology. Philadelphia:

Saunders.

3. Widmann, F. K., Itatani, C. A., &Widmann, F. K. (1998 or latest edition). An

introduction to clinical immunology and serology. Philadelphia: F.A. Davis.

41


Course Code MDU5304

Course Title Laboratory Management

Credit value 03

Core/Optional Core

Prerequisites None


Learning

Assessment Total

34 hrs

(17 Sessions)

06 hrs

(3 DSs)

12hrs

(2 days Lab)

91 hrs



Online [14 hrs] +

Recommended

readings [20 hrs])

02 hrs

(2 CATs x 1 hr)

145hrs

Course Aim/s. ● To provide basic knowledge in laboratory management

PLOs addressed by

course

● PLO 01: Academic Expertise ● PLO 02: Practical Competence ● PLO 04: Teamwork and Leadership ● PLO 05: Creativity and Problem Solving ● PLO 06: Managerial and Entrepreneurship Skills

Course Learning

Outcomes (CLO) Students should be able to: ● CLO 01: Describe general principles of management. (PLO 01) ● CLO 02: Explain the main aspects of laboratory management. (PLO 01) ● CLO 03: Perform basic managerial duties. (PLO 02, PLO 06) ● CLO 04: Develop plans and strategies to improve conditions / overcome problems of a

given scenario (PLO 04, 05, 06) ● CLO 05: Demonstrate abilities in leading and managing (PLO 06)


topics)

● Introduction to management - Definitions and general principles, Concepts of

management, Management functions ● Health laboratory management - Scope of medical laboratory management, Laboratory

planning and organization, Laboratory layout planning and considerations of ergonomics,

Evidence based laboratory administration, Strategic planning ● 3.0 Aspects of laboratory management - Management ethics, Quality management,

Human resource management, Specimen management and processes, Financial

management, Chemical, consumable and stores management, Information management,

Safety management, Medical laboratory waste management

Teaching Learning

methods

● Self- learning: Course material lineon (17 Sessions), Online components, Recommended

readings ● Compulsory contact sessions: Laboratory classes - 02 days x 6hrs ● Non-compulsory contact sessions – 3 Day schools ● Continuous assessments: 2 NBTs ● Final examination: Theory paper

Assessment


Theory (100%): NBTs: 2 x 1.5 hr;



OCAM Computation:




only for 2 years

Theory: 100%


(40 marks) and 02 Essay Questions (30 marks)



1. Harmening, D. (2007 or latest edition). Laboratory management: Principles and processes. St.

Petersburg, Fla: D.H. Pub. & Consulting.

2. Varnadoe, L. A. (1996 or latest edition). Medical laboratory management and supervision:

Operations, review, and study guide. Philadelphia: F.A. Davis Co.

3. Mekonnen, E. (2004 or latest edition), Lecture notes For Medical Laboratory Technology

Students Health Laboratory Management and Quality Assurance, University of Gondar.

42


Course Code MDU5305

Course Title Work Based Training III

Credit value 03

Core/Optional Core

Prerequisites (MDU5401, MDU5303, MDU5206) CR & MDE3208 C grade (MDE3208 - only for lateral

entrants)


- 02hrs

(1 DSs)

156 hrs

(26 days Lab

training)

138 hrs




Recommended

readings [19 hrs])

04hrs

(2 Practical

test x 2 hrs)

300 hrs

Course Aim/s. ● To provide hands on experience in performing laboratory investigations while supporting

the learner to develop competent, ethical and professional and reflective practice.

PLOs addressed by

course

● PLO 01: Academic Expertise ● PLO 02: Practical Competence ● PLO 03: Effective Communication and Networking ● PLO 04: Teamwork and Leadership ● PLO 05: Creativity and Problem Solving ● PLO 07: Information and Data Management Skills ● PLO 08: Ethical Professional Behaviour

Course Learning

Outcomes (CLO) Students should be able to: ● CLO 01: Perform relevant laboratory investigations and evaluate test results (PLO 02,

07) ● CLO 02: Compare results of the laboratory tests with the disease pathologies and

comment on possible diagnosis. (PLO 01) ● CLO 03: Perform all the duties and investigations in the blood bank assigned for the

Medical Laboratory Scientists. (PLO 02) ● CLO 04: Identify possible laboratory errors and develop protocols for quality

improvement. (PLO 01, 05) ● CLO 05: Interact with patients and health care professionals in providing effective patient


(PLO 09) ● CLO 07: Demonstrate professional and ethical behavior in the working environment (PLO

08)


topics)

● Haematology ● Clinical Biochemistry ● Immunology and Serology ● Cytology

Teaching Learning

methods

● Self- learning: Online components, Recommended readings ● Compulsory contact sessions: Laboratory training - 26 days x 6hrs ● Non-compulsory contact sessions – 1 Day school ● Continuous assessments: 2 Practical tests (PT) ● Final examination: 1 Practical test, reflective journal and viva voce

Assessment


Practical (100%): Practical tests – 2x 2 hrs

OCAM Computation:

50% PT1 mark + 50% PT2 mark


compulsory


for the Final exam; Eligibility valid only for 2

years




43


1. Lewis, S. M. and Kumari, S (2000 or latest edition). Guidelines on Standard Operating

Procedures for Haematology. WHO, Reginal Office for South East Asia, New Delhi.



3. Contreras, M. (2009 or latest edition). ABC of transfusion. Chichester, UK: Wiley-

Blackwell Pub.

4. Varley, H., Gowenlock, A. H., McMurray, J. R., McLauchlan, D. M., & Varley, H. (1988

or latest edition). Varley's practical clinical biochemistry. Boca Raton, Fla: CRC Press.

44


Course Code MDU5206

Course Title Cytology

Credit value 02

Core/Optional Core

Prerequisites None


24 hrs

(12 Sessions)

6 hrs

(3 DSs)

12 hrs

(2 days Lab)

56 hrs




readings [07 hrs])

02 hrs

(1 CAT x 1hr)

+ (1 Practical

test 1hr)

100 hrs

Course Aim/s. ● To provide knowledge on gynaecological and non gynaecological cytology including normal

cellular morphology, abnormal features and laboratory evaluation of cytology. ● To develop skills in performing cytological techniques assigned for medical laboratory

scientists.

PLOs addressed by

course


Course Learning

Outcomes (CLO) Students should be able to: ● CLO 01: Discuss the normal and abnormal nuclear, cytoplasmic and background cytological

features of cells in cytological smears. (PLO 01) ● CLO 02: Describe different sources, collection techniques and handling of cytological specimens.

(PLO 01) ● CLO 03: Perform cytological investigations assigned for Medical Laboratory Scientists (PLO 02) ● CLO 04: Evaluate possible errors in cytological procedures, evaluate existing quality assurance

procedures and propose quality assurance measures. (PLO 01, 05, 07)


topics)

● Introduction to cytology – Introduction to cytology, Specimen collection and preparation,

Fixation and staining in cytology ● Non-gynaecological cytology - Exfoliative cytology, Urine, Cyst & joint fluid aspirates,

Cytology of thyroid, Lymph nodes and breast ● Cervical cytology / gynaecological cytology - Cervical cancer classification, smear pattern &

hormonal status, Non / Specific inflammation, SIL lesions ● Quality assurance (QA) and audits in cytology – Quality assurance in sample collection and

preparation, Quality assurance in staining.

Teaching Learning

methods

● Self- learning: Course material in print (12 Sessions), Online components, Recommended

readings ● Compulsory contact sessions: Laboratory classes - 02 days x 6hrs ● Non-compulsory contact sessions – 3 Day schools ● Continuous assessments: 1 NBT + Practical Test (PT)

Assessment




Essay Question (10 marks)

Practical (50%): Practical test – 1 hr

OCAM Computation:


Minimum 50 marks compulsory for PT




Theory: 100%




45


1. Keebler, C. M., Somrak, T. M. (1993 or latest edition). The Manual of cytotechnology. Chicago:

American Society of Clinical Pathology Press.

2. Kooss, L. G. (1961 or latest edition). Diagnostic cytology and its histopathologic basis. London:

Pitman Medical Publishing.

3. Gray, W., & McKee, G. T. (2003 or latest edition). Diagnostic cytopathology. Edinburgh:

Churchill Livingstone.

4. Demay, R. M. (2012 or latest edition). The art and science of cytopathology. Chicago, IL: American

Society of Clinical Pathology.

46


Course Code MDU5407

Course Title Laboratory Automation & Instrumentation

Credit value 04

Core/Optional Core

Prerequisites None



44 hrs

(22 Sessions)

08 hrs

(4 DSs)

36 hrs

(6 days Lab)

109 hrs



Online [13 hrs] +

Recommended

readings [12 hrs])

03 hrs

(1 CAT x

1.5hrs) + 1

Practical test x

1.5 hrs)

200hrs

Course Aim/s. ● To provide knowledge on the basic operation of manual and automated laboratory

instruments. ● To provide practice in operating, maintaining and troubleshooting laboratory instruments.

PLOs addressed by

course

● PLO 01: Academic Expertise ● PLO 02: Practical Competence ● PLO 05: Creativity and Problem Solving

Course Learning

Outcomes (CLO) Students should be able to: ● CLO 01: Explain the theories and operating principles of manual and automated laboratory

instruments. (PLO 01) ● CLO 02: Discuss the applications of various analytical instruments in medical diagnosis &

research. (PLO 01) ● CLO 03: Operate, maintain and troubleshoot laboratory equipment. (PLO 02, 05) ● CLO 04: Evaluate the quality control procedures used in analyzers. (PLO 01, 05) ● CLO 05: Outline limitations of automated analyzers and comment on possible

improvements. (PLO 01, 05)


topics)

● Instrumentation – Principles and applications of photometry, Principles and applications

of spectrometry, Principles and applications of spectroscopy, Principles and applications

of chromatography, Principles and applications of electrophoresis, Principles and

applications of luminometry, Principles and applications of fluorometry, Principles and

applications of other instrument. ● Introduction to automation – Introduction to laboratory automation, Role of computers in

automated systems, Automation in specimen processing, Automation of volumetric

measurements and calibration, Measurement of ion activity and potentiometry,

Voltammetry, coulometry and conductometry, Communications and laboratory networks ● Automated systems in the laboratory - Automation in Haematology, Automation in

biochemistry, Automation in histopathology, Automation in Microbiology, Other

automated systems in the laboratory, Analytical errors and Quality assurance in automated

systems, Trouble shooting and maintenance of automated analyzers.

Teaching Learning

methods


readings ● Compulsory contact sessions: Laboratory classes - 06 days x 6hrs ● Non-compulsory contact sessions – 4 Day schools ● Continuous assessments: 1 NBT, 1 Practical Test (PT) ● Final examination: 1 Theory paper

Assessment


Theory (50%): NBT: 1 x 1.5hrs;




OCAM Computation:






Theory: 100%





47


1. Cheesbrough, M. (2005 or latest edition). District laboratory practice in tropical countries.


2. Gunathilaka, M.M., De Silva D.K. &Hunais H.M., (2004-2005 or latest edition) Guidelines for

maintenance of Equipment in a Clinical Chemistry Laboratory. Department of Biochemistry,

Medical Research Institute, Colombo, WHO Biennium.

3. Varley, H., Gowenlock, A. H., McMurray, J. R., McLauchlan, D. M., & Varley, H. (1988 or

latest edition). Varley's practical clinical biochemistry. Boca Raton, Fla: CRC Press.

4. Enderle, J.D., Blanchard, S.M., Bronzino, J.D., (2nd edition). Introduction to Biomedical

Engineering, Elsevier academic press.

48


Course Code MDU5308

Course Title Research Methodology

Credit value 03

Core/Optional Core

Prerequisites None


42 hrs

(21 Sessions)

08 hrs

(4 DSs)

06 hrs

(1 day lab)

92 hrs



Online [13 hrs] +

Recommended

readings [13 hrs])

02 hrs

(2 CATs x 1

hr)

150hrs

Course Aim/s. ● To provide knowledge and skills in researching.

PLOs addressed by

course

● PLO 01: Academic Expertise ● PLO 02: Practical Competence ● PLO 03: Effective Communication and Networking ● PLO 05: Creativity and Problem Solving ● PLO 07: Information and Data Management Skills

Course Learning

Outcomes (CLO) Students should be able to: ● CLO 01: Discuss the main aspects of researching (PLO 01) ● CLO 02: Identify research problems and construct hypothesis (PLO 01, 05) ● CLO 03: Evaluate ethical issues in conducting research. (PLO 01) ● CLO 04: Design research applying principles of qualitative and quantitative research

methods (PLO 01,05) ● CLO 05: Validate data collection tools and laboratory investigations in research. (PLO

01, 02) ● CLO 06: Process and present data using appropriate manual and computer based

methods (PLO 03, 05, 07)


topics)

● Introduction to research - Introduction to research, The research process ● Research problem – Reviving the literature, Formulating a research problem,

Identifying variables, Constructing hypothesis ● Research design – The research design, Selecting a study design ● Sample – Population and sample, Selecting a sample ● Data collection – Methods of data collection, Ethical issues in data collection,

Establishing the validity and reliability of a research instrument, Laboratory

investigations in research ● Processing and presenting data – Processing data, Software for data processing and

presenting ● Presenting and report writing – Reference writing, Proposal writing, Report writing,

Article writing, Research presentation

Teaching Learning

methods


Recommended readings ● Non-compulsory contact sessions – 5 Day schools ● Compulsory contact sessions: Laboratory class - 01 day x 6hrs ● Continuous assessments: 2 NBTs ● Final examination: 1 Theory paper


Theory (100%): NBTs: 2 x 1.5 hr;



OCAM Computation:




for 2 years

Theory: 100%






1. Creswell, J. W. (2003 or latest edition). Research design: Qualitative, quantitative, and mixed

method approaches. Thousand Oaks, Calif: Sage Publications.

2. Miles, M. B., & Huberman, A. M. (1994 or latest edition). Qualitative data analysis: An

expanded sourcebook. Thousand Oaks: Sage Publications.

49


Course Code MDU5209

Course Title Advanced Techniques in Medical Laboratory Sciences Credit value 02

Core/Optional Core

Prerequisites None



20 hrs

(10 Sessions)

04 hrs

(2 DSs)

18 hrs

(3 days Lab)

56 hrs


Practical [09hrs] +

Online [10 hrs] +

Recommended

readings [07 hrs])

02 hrs

(2 CATs x

1hr)

100 hrs

Course Aim/s. ● To provide theoretical and practical knowledge on laboratory techniques used in protein

sequencing, vitamin and mineral estimation and animal studies.

PLOs addressed by

course

● PLO 01: Academic Expertise ● PLO 02: Practical Competence

Course Learning

Outcomes (CLO) Students should be able to: ● CLO 1: Perform protein analysis and sequencing (PLO 01, PLO 02) ● CLO 2: Explain the basic concepts of nanotechnology and their applications in health

care (PLO 01) ● CLO 3: Explain the basic aspects of animal studies. (PLO 01)


topics)

● Protein extraction, separation and sequencing - General aspects of protein analysis,

Sample preparation, Protein electrophoresis, Determination of composition and

sequencing. ● Introduction to nanotechnology – Introduction to nanotechnology, Applications of

nanotechnology in health care. ● Animal Studies – History and applications of animal studies, Handling of laboratory

animals, Animal models, Animal studies

Teaching Learning

methods

● Self- learning: Course online (10 Sessions), Online components, Recommended

readings ● Compulsory contact sessions: Laboratory classes - 03 days x 6hrs ● Non-compulsory contact sessions – 4 Day schools ● Continuous assessments: 2 NBTs ● Final examination: 1 Theory paper

Assessment


Theory (100%): NBTs: 2 x 1 hr; 10 MCQs (10 marks) + 02 SEQs (80 marks) + 01


OCAM Computation:




for 2 years

Theory: 100%

1 paper: 2 hrs;

of 20 MCQs (20 marks), 03 SEQs (60

marks) and 01 Essay Question (20

marks)



1. Rosenberg, I. M. (2005 or latest edition). Protein analysis and purification. Boston:

Birkhauser.

2. Robert A Meyers. (2015 or latest edition). Synthetic biology: advances in molecular biology

medicine. Weinheim Wiley-VCH.

3. Harry F Tibbals. (2011 or latest edition). Medical nanotechnology and nanomedicine. Boca

Raton [etc.]: CRC Press.

4. Hau, J., Gerald, L., Hoosier, J.R.V., (Latest edition) Hand book of laboratory animal science,

CRC press.

50


Course Code MDU5210

Course Title Special Topics in MLS

Credit value 02

Core/Optional Optional

Prerequisites None



- 12hrs

(4 Seminars)

12hrs

(2 days Lab)

68 hrs

(Practical [06hrs] +

Online [32 hrs] +

Recommended

readings [30])

08hrs

(2 assignments)

100hrs

Course Aim/s. ● To introduce recent technical and practical advancements to undergraduates and make

them engage in social activities in order to develop their attitudes towards self-learning and

social responsibility.

PLOs addressed by

course

● PLO 01: Academic Expertise ● PLO 02: Practical Competence ● PLO 03: Effective Communication and Networking ● PLO 04: Teamwork and Leadership ● PLO 05: Creativity and Problem Solving ● PLO 06: Managerial and Entrepreneurship Skills ● PLO 07: Information and Data Management Skills ● PLO 08: Ethical Professional Behaviour ● PLO 09: Self-management and Lifelong Learning

Course Learning

Outcomes (CLO) Students should be able to: ● CLO 01: Recall latest technical and practical advancements in the field of medical laboratory

sciences. (PLO 01, 09) ● CLO 02: Compare existing techniques and practices with new trends and identify areas to

be improved. (PLO 02,05, 07) ● CLO 03: Demonstrate effective communication and ability in developing productive

relationships with people at different levels. (PLO 03) ● CLO 04: Demonstrate the ability in working with and through the others in achieving

objectives of the study. (PLO 04, 06) ● CLO 05: Exhibit the competency in setting up goals, designing strategies and managing the

conditions towards achieving goals. (PLO 05, 09) ● CLO 06: Demonstrate professional and ethical behavior. (PLO 08)


topics)

● Scientific seminars related to current scenarios ● Organize and conduct social activities related to Medical Laboratory Sciences

Teaching Learning

methods

● Self- learning: Online components, Recommended readings ● Compulsory contact sessions: Laboratory classes - 02 days x 6hrs ● Non-compulsory contact sessions – 4 seminars ● Continuous assessments: 2 Assignments ● Final examination: Report and Viva voce


Assignments (100%): 2 x 4 hrs

OCAM Computation:

50% Assignment 1 mark+ 50% Assignment 2 mark



years

Report (70%)

Viva voce (30%) - 15 mins


Required readings of books. journals and newspaper articles related to the selected special

topics.

51


Course Code MDU5211

Course Title Healthcare Informatics

Credit value 02


Prerequisites None



28hrs

(14 Sessions)

06 hrs

(3 DSs)

06 hrs

(1day Lab)

58 hrs



Online [08 hrs] +


[05 hrs])

02 hrs

(2 CATs x 1

hr)

100 hrs

Course Aim/s. ● To provide necessary knowledge and practice in healthcare information management.

PLOs addressed by

course


Course Learning

Outcomes (CLO) Students should be able to: ● CLO 01: Explain the importance of information management in health care systems (PLO

01) ● CLO 02: Explain the applications of latest “Information Management Systems” (IMS) in

healthcare information management and administration. (PLO 01) ● CLO 03: Outline the basic steps in securing privacy and confidentiality IMS. (PLO 01) ● CLO 04: Perform basic operations of data management using IMS. (PLO 02, 07) ● CLO 05: Evaluate the procedures of assuring quality of information in IMS (PLO 01, 05)


topics)

Introduction to health informatics, Theories and health care informatics literacy,

Informatics application in administration, research and education, Healthcare

Information systems, Basic computer competencies, Confidentiality, Privacy and

security of healthcare information, Using search engines and electronic health records,

Health IT technology infrastructure, Assessing quality of information, Practices of

health informatics in Sri Lanka, Health information exchange, Public health information

and data, Data presentation, Selection, implementation, evaluation, and management of

healthcare information systems

Teaching Learning


readings


● Compulsory contact sessions: Laboratory class - 01 day x 6hrs

● Continuous assessments: 2 NBTs



Theory (100%): 2 x 1 hr; 10 MCQs (10 marks) +

02 SEQs (80 marks) + 01 Essay Question (10

marks)

OCAM Computation:




for 2 years

Theory: 100%


SEQs (60 marks) and 01 Essay Question

(20 marks)



1. Coiera, E. (2015). Guide to health informatics. Boca Raton: CRC Press, Taylor & Francis

Group.

2. Shortliffe, E. H., &Cimino, J. J. (2014). Biomedical informatics: computer applications in

healthcare and biomedicine. New York, NY: Springer.

3. Nelson, R., & Staggers, N. (2014). Health informatics: an interprofessional approach. St.

Louis, MO: Elsevier.

52


Course Code MDU5212

Course Title Literature Review

Credit value 02


Prerequisites None


- 04 hrs

(02 DS)

06 hrs

(1 workshop)

170 hrs

(survey and review of

literature [160 hrs] +

Recommended reading

of texts [10])

20 hrs

(01

Presentation; 01

Report)

200hrs

Course Aim/s. ● To develop skills in the retrieval and critical analysis of scientific information relevant to

a particular subject area.

PLOs addressed by

course

● PLO 01: Academic Expertise ● PLO 02: Practical Competence ● PLO 03: Effective Communication and Networking ● PLO 05: Creativity and Problem Solving ● PLO 07: Information and Data Management Skills ● PLO 08: Ethical Professional Behaviour ● PLO 09: Self-management and Lifelong Learning

Course Learning

Outcomes (CLO) Students should be able to: ● CLO 01: Conduct a systematic search of the published research literature in a given topic

using a variety of information retrieval sources/tools. (PLO 01, 02, 07, 09) ● CLO 02: Select and summarize the information based on their relevance to the topic.

(PLO 02, 05, 07) ● CLO 03: Critically examine the literature evaluating their contributions to the

understanding of the topic. (PLO 01, 05, 07) ● CLO 04: Write a structured review report, using the prescribed format with source

material appropriately referenced. (PLO 03, 07, 08)


topics)

Student will select and review a topic of research of their choice. Will involve searching

for literature, sorting and prioritizing the literature, analytical reading and evaluation of

papers, comparison across studies and finally writing a well-organized, structured

review including a critical analysis and synthesis of the findings to highlight gaps or

directions that will help formulate new research questions/hypothesis. This course

requires the student to work independently with minimal supervision

Teaching Learning

methods

● Literature survey and information retrieval, Review of literature; Planning, organizing

and writing a critical review, recommended reading of text books ● Contact sessions – 02 Day schools (04 hrs), workshop (06 hrs) ● Continuous Assessments (CA): 01 Presentation + 01 Review report – based on analyzing

a research article, applying relevant literature review and presentation skills ● Final examination: Report and presentation

Assessment


Topic presentation (30%)

Critical review of a research article (70%)

OCAM Computation:

30% Presentation + 70% Report

Attendance at both CATs is compulsory



only for 2 years

Final Report: 70%

Presentation: 30%


1. Ridley, D. (2013). The literature review: A step-by-step guide for students. London: SAGE.

2. Burton, J. (March 01, 2011). Book review: Literature reviewing. Journal of English for

Academic Purposes.

53

Semester and Level Semester 01 & 02- Level 06

Course Code MDU6800

Course Title Research Project

Credit value 08

Core/Optional Core

Prerequisites MDU5308 C & BSU4230 C


- 08 hrs

(4 DSs)

-

752 hrs

(research activities [732hrs]

+ contact with supervisor/s

[20hrs])

40 hrs

(2 Presentations + 2

Reports)

800hrs

Course Aim/s. ● To train students in designing and conducting independent scientific research

PLOs addressed by

course


Course Learning

Outcomes (CLO) The students should be able to; ● CLO 01: Frame relevant research questions/ hypotheses for investigation. (PLO 05, 07) ● CLO 02: Design and carryout research-based projects to create new knowledge, using

appropriate and current methodologies and tools. (PLO 01, 02, 04, 05, 08, 09) ● CLO 03: Search and review literature from libraries, journal databases and other information

sources. (PLO 07) ● CLO 04: Analyze research data, using suitable statistical methods where relevant, to generate

useful information. (PLO 02, 07) ● CLO 05: Communicate research findings through presentations and scientific reports,

demonstrating effective oral and written communication skills. (PLO 03) ● CLO 06: Conduct research activities in a responsible manner adhering to research ethics,

whilst demonstrating a broad understanding of issues and administrative frameworks

associated with research ethics (PLO 02, 08) ● CLO 07: Demonstrate generic skills including critical thinking; skills to address new

research questions/challenges and research setbacks; planning and goal setting, time

management skills; leadership and teamwork skills, etc. (PLO 05, 04, 06, 09)


topics)

Student will design and conduct a research study under the guidance of a supervisor. It would be

conducted as a group project (2-3 members) but will require a high degree of independent work.

Student will review literature relevant to the topic and formulate research questions/hypothesis.

Data collection activities will be for about 2-3 months. Findings of the research project must be

analysed and communicated in the written form in a scientific report using correct formats and

styles and presented orally

Teaching Learning

methods Literature survey (100 hrs), Planning and Data collection (400 hrs), Data analysis & writing

reports (272 hrs)

Contact sessions – 4 Day schools (08 hrs); Contact with supervisor/s (20 hrs)

Continuous Assessments (CA): 2 Reports + 2 Presentations

Final examination: 1 Theory paper, Final report and Viva voce

Assessment


Proposal assessment: 70% Proposal +

30% Presentation

Progress assessment: 70% Progress

report + 30% Presentation

OCAM Computation:

70% Progress Assessment + 30%

Project proposal Assessment

Attendance at all components is

compulsory

Theory paper: 20%

Final Report: 70 %

Viva voce: 10%

54

Minimum OCAM of 40% is required

to be eligible for the Final exam;

Eligibility valid only for 2 years


No recommended test books: Students should read articles relevant to the research project

55

Semester and Level Semester 01- Level 06

Course Code MDU6301

Course Title Cytogenetics and Molecular Genetics

Credit value 03

Core/Optional Core

Prerequisites None


46 hrs

(23 Sessions)

08 hrs

(4 DSs)

12 hrs

(2 days Lab)

81 hrs




readings [03 hrs])

3 hrs

(1 CAT x 1.5

hrs) + (1

Practical test

1.5 hr)

150

hrs

Course Aim/s. ● To provide knowledge on cytogenetics, molecular genetics and basic molecular

diagnostics methods, and to provide necessary practice in basic molecular diagnostic

methods.

PLOs addressed by

course

● PLO 01: Academic Expertise ● PLO 02: Practical Competence ● PLO 05: Creativity and Problem Solving ● PLO 07 Information and Data Management Skills ● PLO 08: Ethical Professional Behaviour

Course Learning

Outcomes (CLO) The students should be able to; ● CLO 01: Explain the main aspects of cytogenetics and molecular genetics (PLO 01) ● CLO 02: Describe the ethical aspects involved in genetics. (PLO 01, 08) ● CLO 03: Perform basic molecular diagnostic methods and evaluate the results. (PLO 02,

05) ● CLO 04: Evaluate the current applications of molecular biological techniques and propose

new applications. (PLO 01, 05, 07)


topics)

● Cytogenetics – Chromosome morphology & Cytogenetic Nomenclature, Cell division

and gametogenesis, Introduction to embryological development, Mechanisms of

chromosomal abnormalities, Chromosome abnormalities in birth defects, Chromosome

abnormalities in malignancies ● Molecular genetics DNA and RNA structure, Human genome and genetic variations,

Patterns of inheritance, Genetic counselling ● Special topics - Biochemical genetics, Pharmacogenetics and Pharmacogenomics,

Molecular Microbiology, Assisted reproductive techniques and stem cells, Ethics in

Genetics ● Bioinformatics Introduction to Bioinformatics tools, Bioinformatics databases, Retrieving

and analyzing sequence data, Designing genotyping assays ● Diagnostic methods Chromosome culture and karyotyping, Special cytogenetic

techniques, DNA/RNA amplification using PCR/RT-PCR, Post PCR processing

Teaching Learning

methods



Assessment






OCAM Computation:






for 2 years

Theory: 100%



(30 marks)


56


1. Snustad, D.P. &Simmon M.J. (1988 or latest edition), Principles of Genetics. John Wiley &

Sons.

2. Brown, T.A. (2006 or latest edition), Genommes, Garland Science.

3. Claverie, J.M. &Notredame, C. (2014 or latest edition), Bioinformatics for Dummies, Wiley

publisher.

57


Course Code MDU6302

Course Title Public Health Microbiology

Credit value 03

Core/Optional Core

Prerequisites None


Independent

Learning

Assessment Total

30 hrs

(15 Sessions)

06 hrs

(3 DSs)

18 hrs

(3 days Lab)

88 hrs



Online [15 hrs] +

recommended

readings [19 hrs])

03 hrs

(1 CAT x

1.5hrs) + (1

Practical test x

1.5 hrs)

145 hrs

Course Aim/s. ● To provide knowledge and develop capacity in responding public health threats

PLOs addressed by

course


Course Learning

Outcomes (CLO) Students should be able to: ● CLO 01: Discuss possible public health issues caused by microorganisms, their

laboratory investigations, control and prevention strategies applied. (PLO 01). ● CLO 02: Perform appropriate laboratory investigations in diagnosis, outbreak

assessment, surveillance, and epidemiological studies. (PLO 02). ● CLO 03: Evaluate available public health surveillance Programmes and propose

improvements. (PLO 05, 07) ● CLO 04: Identify public health issues which need further investigations and design

epidemiological studies. (PLO 01, 05, 07)


topics)

● Infectious diseases and Public health microbiology - Introduction to Public Health,

Microbiome, Vector borne diseases, Water borne infections, Laboratory diagnosis of

water borne infections, Food borne Infections and Food poisoning, Laboratory diagnosis

of Food borne infections, Hospital acquired infections, Bioterrorism, Bioterrorism –

Bacterial agents

● Surveillance and Monitoring health - Basics of epidemiology, Epidemiologic methods,

Public health surveillance, Investigation outbreaks, Typing methods

Teaching Learning


readings










OCAM Computation:






only for 2 years

Theory: 100%



(30 marks)


58


1. Emergency preparedness and response, (2014). Centers for Disease control and

Prevention.URL: https://emergency.cdc.gov.

2. Mandell, G. L., Douglas, R. G., Bennett, J. E., & Dolin, R. (2005 or latest edition). Mandell,

Douglas, and Bennett's principles and practice of infectious diseases. New York:

Elsevier/Churchill Livingstone.

3. Ray, B. (1996 or latest edition). Fundamental food microbiology. Boca Raton: CRC Press.

https://emergency.cdc.gov/

59


Course Code MDU6503

Course Title Clinical Biochemistry III

Credit value 05

Core/Optional Core

Prerequisites None



56 hrs

(28 Sessions)

10 hrs

(5 DSs)

42 hrs

(7 days Lab)

138 hrs



Online [16 hrs] +


[17 hrs])

4 hrs

(1 CAT x 1.5

hrs) + (1

Practical test 2.5

hrs)

250 hrs

Course Aim/s. ● To provide knowledge on biochemical aspects of the major systems of the body, changes in

disease conditions and laboratory diagnosis of these changes. ● To provide opportunity to develop skills in performing biochemical investigations while

maintaining the standard practices.

PLOs addressed by

course


Course Learning

Outcomes (CLO) The students should be able to: ● CLO 01: Describe biochemical processes of major systems of the body, changes in disease

conditions and their laboratory diagnosis process. (PLO 01) ● CLO 02: Perform routine and advanced biochemical investigations, evaluate test results

and comment on possible disease conditions. (PLO 02, 05, 07) ● CLO 03: Describe the analytical techniques used in tumour marker analysis and therapeutic

drug monitoring. (PLO 01) ● CLO 04: Discuss biochemical aspects of major vitamins and minerals of the body and

perform relevant biochemical investigations (PLO 01) ● CLO 05: Identify pre – analytical, analytical and post analytical errors and develop

protocols to minimize these errors. (PLO 02, 05, 07)


topics)

● Kidney diseases and kidney function tests – Functions of the kidney and kidney diseases,

Kidney function tests. ● Liver diseases and liver function tests – Functions of the liver and Liver diseases, Liver

function tests ● GI diseases and laboratory diagnosis – Biochemical functions of GI tract and its disorders,

Laboratory evaluation of GI diseases. ● Cardiac diseases and laboratory diagnosis – Evaluation of cardiac function, Cardiac

disorders and laboratory diagnosis. ● Endocrinology - Classification, Biosynthesis and regulation of hormones, Hormone

secretion, Laboratory estimation of hormones, Thyroid hormones, Adrenal hormones,

Reproductive hormones. Other hormones ● Pregnancy, prenatal and postnatal testing – Laboratory investigations related to pregnancy,

Prenatal and Postnatal screening and disease diagnosis. ● Vitamins - Chemistry and functions of vitamins, Laboratory evaluation of vitamins ● Minerals and Trace elements – Biological importance of Minerals, Iron metabolism and

laboratory evaluation, Calcium, Phosphorous and Magnesium metabolism and laboratory

evaluation, Trace elements, Introduction to toxicology. ● Tumour markers – Introduction to tumour markers, Clinically important tumour markers

and their laboratory evaluation. ● Therapeutic drug monitoring: Introduction to pharmacology, Therapeutic drug

monitoring

Teaching Learning

methods




60

Assessment

strategy Theory (50%): NBT: 1 x 1.5hrs ;




OCAM Computation:






years

Theory: 100%

1 paper – 3hrs; 30 MCQs (30 marks), 04 SEQs

(40 marks) and 02 Essay Questions (30

marks)



1. Burtis, C. A., Ashwood, E. R., Border, B., &Tietz, N. W. (2001 or latest edition). Tietz


2. Cheesbrough, M. (2005 or latest edition). District laboratory practice in tropical countries.


3. White, A., Handler, P., & Smith, E. L. (1973 or latest edition). Principles of biochemistry. New

York: McGraw-Hill,.

61


Course Code MDU6404

Course Title Medical Laboratory Quality Management & Accreditation

Credit value 04

Core/Optional Core

Prerequisites None


54 hrs

(27 Sessions)

10 hrs

(5 DSs)

12 hrs

(2 days Lab)

121 hrs



Online [19 hrs] +


[15 hrs])

3 hrs

(2 CATs x 1.5

hrs)

200 hrs

Course Aim/s. ● To provide knowledge on quality assurance, leadership, personnel management, operations

management, financial management and laboratory informatics. ● To provide overall knowledge and experience in the process of accreditation.

PLOs addressed by

course

● PLO 01: Academic Expertise ● PLO 02: Practical Competence ● PLO 05: Creativity and Problem Solving ● PLO 06: Managerial and Entrepreneurship Skills ● PLO 07: Information and Data Management Skills

Course Learning

Outcomes (CLO) The students should be able to: ● CLO 01: Describe total quality management in a laboratory. (PLO 1) ● CLO 02: Explain personnel, financial and operational management theories. (PLO 1) ● CLO 03: Design a laboratory quality management system. (PLO 02, 05, 06) ● CLO 04: Describe the process of accreditation of medical laboratory. (PLO 1) ● CLO 05: Prepare documents for laboratory accreditation. (PLO 02, 06, 07)

● CLO 06: Plan and conduct internal audits. (PLO 02, 06, 07)


topics)

● Quality assurance: Introduction to Quality Assurance (QA), Concepts of Quality Control,

QA procedures, Root cause analysis in troubleshooting, Establishment of verification of

method performance specifications, Quality indicators, Internal audit

● Leadership: The Laboratory Medical Director: Roles, Responsibilities and Expectations, The

Laboratory Manager/Supervisor: Roles, Responsibilities and Expectations, Management

Theory: Applying Emotional Intelligence in the Healthcare Environment, Delivering

Effective Presentations, Basic Elements of the Strategic Process

● Personnel management: Setting Performance Expectations, Appraising Employee

Performance, Maintaining Ethics in the Laboratory, preparation of Job Description

● Operations management: Developing Quality management Systems, Preparing Standard

Operating Procedures and maintaining proper reporting documentation

● Financial management: Preparation of annual budgetary requirements, LEAN

management, Purchasing procedures/ procurement, Equipment selection and procurement

procedure including preparation of specifications

● Informatics: Laboratory Management Information Systems in Daily Practice

● Laboratory accreditation: Management requirements, Technical requirements, Laboratory

information management, Laboratory information system

Teaching Learning

methods ● Self- learning: Course material online(27 Sessions), Online components, Recommended

readings



● Continuous assessments: 2 NBTs


Assessment


Theory (100%): 2 x 1.5 hrs; 10 MCQs (10 marks) + 04 SEQs (80 marks) + 1


OCAM Computation:


Theory: 100%


SEQs (40 marks) and 02 Essay Questions (30

marks)


62



for 2 years


1. Westgard, J. O., & Barry, P. L. (2010 or latest edition). Basic QC practices: Training in

statistical quality control for medical laboratories. Madison, WI: Westgard QC.

2. Harmening, D. (2007 or latest edition). Laboratory management: Principles and processes. St.

Petersburg, Fla: D.H. Pub. & Consulting.

3. Varnadoe, L. A. (1996 or latest edition). Medical laboratory management and supervision:

Operations, review, and study guide. Philadelphia: F.A. Davis Co.

4. Mekonnen,E (2004). LECTURE NOTES for Medical Laboratory Technology Students:

Health Laboratory Management and Quality Assurance. University of Gondar.

5. Varnadoe, L.A. (2008 or latest edition), Medical Laboratory Management and Supervision,

Amazon.com, Inc.

6. Mekonnen, E. (2004 or latest edition), Health Laboratory Management and Quality

Assurance: LECTURE NOTES for Medical Laboratory Technology Students, University

of Gondar.

7. ISO 15189: Medical laboratories: Requirements for quality and competence (2012).

8. EP29-A: Expression of Measurement Uncertainty in Laboratory Medicine, Approved

Guideline Clinical and Laboratory Standards Institute, (2012).

63


Course Code MDU6705

Course Title Work Based Training IV

Credit value 07

Core/Optional Core

Prerequisites (MDU 6301, MDU6503, MDU 6404) CR


- 02hrs

(1 DSs)

390 hrs

(65 days Lab

training)

304 hrs




Recommended

readings [14 hrs])

04 hrs

(2 Practical tests

x 2 hrs)

700 hrs

Course Aim/s. ● To provide hands on experience in performing advanced laboratory procedures while

supporting learner to develop competent, ethical and reflective professional practice.

PLOs addressed by

course


Course Learning

Outcomes (CLO) Students should be able to: ● CLO 01: Perform routine and special medical laboratory tests and evaluate test results

(PLO 02, 05) ● CLO 02: Compare results of the laboratory tests with the disease pathologies and

comment on possible diagnosis. (PLO 01, 05, 07) ● CLO 03: Identify possible laboratory errors and develop protocols for quality

improvement. (PLO 01, 05) ● CLO 04: Evaluate standard laboratory safety procedures and risk management and

propose possible improvements. (PLO 01, 05) ● CLO 05: Interact with patients and health care professionals in providing effective patient


and demonstrate the ability in updating themselves to the latest advancements in the

field. (PLO 09) ● CLO 07: Demonstrate professional and ethical behavior in the working environment

(PLO 08) ● CLO 08: Demonstrate the competency in basic aspect of laboratory management. (PLO

06) ● CLO 09: Outline the basic requirements in setting up businesses in the field of Medical

Laboratory Sciences and develop plans in developing, promoting and overcoming

issues. (PLO 06) ● CLO 10: Develop a responsible and mature approach to assigned duties and

responsibilities. (PLO 09)


topics)

● Clinical biochemistry ● Bacteriology, Virology & Mycology ● Haematology ● Histopathology and Cytology ● Molecular biology ● Laboratory management

Teaching Learning

methods ● Self- learning: Online components, Recommended readings

● Compulsory contact sessions: Laboratory training - 65 days x 6 hrs

● Non-compulsory contact sessions – 1 Day school

● Continuous assessments: 2 Practical tests (PT)

● Final examination: 1 Practical test, Reflective journal and Viva voce


64

Assessment

strategy Practical (100%): Practical test – 2 x 2hrs

OCAM Computation:

50 % PT1 mark + 50% PT2 mark


compulsory



only for 2 years





1. 1. Lewis, S. M. (2007 or latest edition). Laboratory Practice. 1007-1021.

2. Kumari, S., Ichhpujani, R. L. (2000 or latest edition). Guidelines on Standard Operating

Procedures for Microbiology. WHO, Reginal Office for South East Asia, New Delhi.

3. Burtis, C. A., Ashwood, E. R., Border, B., &Tietz, N. W. (2001 or latest edition). Tietz


4. Robert A Meyers. (2015 or latest edition). Synthetic biology: advances in molecular biology

medicine. Weinheim Wiley-VCH.



bachelor of medical laboratory sciences honours degree

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