Enzyme actionWALT: To be able to describe how enzymes work.WILF: ~ Recall what the word denatured means. (D)~ Describe how factors (temperature, pH and concentration) can affect the activity of enzymes. (C)~ Explain the model of the ‘Lock and Key’ hypothesis of showing how enzymes work. (B)~ Explain how enzymes work referring to the active site and how it can be affected . (A/A*)

Keywordsenzyme active site Lock and Key

hypothesis substrate

Substrate molecules

EnzymeActive site

Product

The ‘lock and key’ hypothesis

Reaction happens (bonds either made or broken)

Enzymes have a specific 3D structure

Enzyme-substrate complex

Breaker Enzymes

Enzymes

Builder Enzymes

Enzymes

The ‘lock and key’ hypothesisTask: Copy this

image, label and add notes to explain how the ‘lock and key’ hypothesis works.Keywords

enzyme substrate active site 3D shape specific reaction product

A change in temperature or pH can affect the bonds that hold the protein together. This causes the enzyme to denature, loose its shape.

The ‘lock and key’ hypothesis

Factors which affect enzyme reactions

Use information on pg 54 to make notes on how each factor affects the rate of reaction.

Enzyme triominoes 1.Cut out all

your triangle pieces.

2.Match up a question with an ANSWER.

3.Create 3 of your own question and answers.

4.Glue into your books.

You should end up with a triangle shape like

the one above.

The ‘lock and key’ hypothesis

Copy and label the diagram from the board and then use the keywords to fill in the gaps.

Enzymes have a ________________ 3d shape.

The molecules that enzymes work on are called ____________. This molecule fits into the enzymes ____________ _________, this is a different shape in each type of enzyme.

The reaction takes place, this could involve ________ being made or broken. After the reaction the ____________ is released.

The ‘lock and key’ hypothesis

Copy and label the diagram from the board and then use the keywords to fill in the gaps.

Enzymes have a ________________ 3d shape.

The molecules that enzymes work on are called ____________. This molecule fits into the enzymes ____________ _________, this is a different shape in each type of enzyme.

The reaction takes place, this could involve ________ being made or broken. After the reaction the ____________ is released.

The ‘lock and key’ hypothesis

Copy and label the diagram from the board and then use the keywords to fill in the gaps.

Enzymes have a ________________ 3d shape.

The molecules that enzymes work on are called ____________. This molecule fits into the enzymes ____________ _________, this is a different shape in each type of enzyme.

The reaction takes place, this could involve ________ being made or broken. After the reaction the ____________ is released.

The ‘lock and key’ hypothesis

Copy and label the diagram from the board and then use the keywords to fill in the gaps.

Enzymes have a ________________ 3d shape.

The molecules that enzymes work on are called ____________. This molecule fits into the enzymes ____________ _________, this is a different shape in each type of enzyme.

The reaction takes place, this could involve ________ being made or broken. After the reaction the ____________ is released.