AUTHOR INDEX

August 15, 1998

Adler, G., 3551Aikou, T., 3727Anderson, L. M., 3590Antalis, T. M., 3719Arnold, A., 3706Arosarena, O., 3668Azzara, M., 3504

Bagnasco, L., 3654Balazs, M., 3555Balczon, R., 3611Barr, F. G., 3542Barre«,J. C., 3579Barry, P., 3508Bartholomew, J., 3712Beamer, W. G., 3694Behari, N., 3649Bell, D. A., 3603Bennicelli, J. L., 3542Bezdek, T., 3504Booth, C. L., 3641Boothman, D. A., 3712Bougnoux, P., 3529Bourdon, M. A., 3743Brix, G., 3598Brou wer, K. L. R., 3641Brouwer, K. R., 3641Brown, S. B., 3706Bruno, S., 3654

Canister, M., 3668Carroll, P. R., 3555Castranio, T., 3603Chaney, S. G., 3579Chang, J., 3504Chapman, J. D., 3571Chasovskikh, S., 3495Chen, J., 3504Chen, L-C, 3677

Chen, S. L., 3561Chen, Z., 3668Cheng, A., 3611Chu, L., 3555Chung, D. C., 3706Churchill, G. A., 3694Clark, S. J., 3508Clerico, L., 3654Colella, G., 3654Collins, C., 3677Colon, I., 3668Corbett, S. A., 3586

Dairkee, S. H., 3677Danks, M. K., 3627Davis, E. M., 3561Davis, R. J., 3542Deryugina, E. I., 3743Devetten, M., 3538DeVries, S., 3555Dimtchev, A., 3495Diwan, B. A., 3590Dong, G., 3668Dritschilo, A., 3495Dubauskas, Z., 3561Dünn,D., 3538Durand, R. E., 3547

Eicher, E. M., 3694El-Deiry, W. S., 3513

English, N. M., 3736Essig, M., 3598

Fawcett, J., 3719Henning, M. C„3571Flossmann-Käst, B. B. M., 3551

Foe, J. L. T., 3538Foty, R. A., 3586France, J., 3660Fujiwara, T., 3499Fukuchi, T., 3526

Ginsberg, J. P., 3542Giorello, L., 3654Golberg, J. L., 3571Gotley, D. C., 3719Gottlob, K., 3566Graeme-Cook, F., 3706

Graessmann, A., 3566

Hamada, K., 3700Hamilton, T. C., 3579Han, K., 3751Harding, C. V., 3660Hartmann, A., 3712Hawighorst, H., 3598Hirohashi, S., 3526, 3700Hochadel, J. F., 3590Hoeflich, A., 3551Honkanen, R. E., 3611Horwitz, S. B., 3620Hovey, R. M., 3555Husain, S. R., 3649Huschtscha, L. I., 3508Hyman, R., 3736

Ichikawa, T., 3561Ichikawa, Y., 3561Ichinose, M., 3751

Jehle, P. M., 3551Jen, J., 3513Jensen, R. T., 3706Johnsen, A., 3660Johnson, B. H., 3684Johnston, S. L., 3519Jones, A. B., 3590Jung, M., 3495

Kaneko, Y., 3751Kherzai, A. W., 3504Killary, A. M., 3533Kim, S., 3538Kimura, S., 3751Klatzmann, D., 3529Knapstein, P. G., 3598Knopp, M. V., 3598Kohno, T., 3700Koons, J. S., 3611Kreitman, R. J., 3649Kunkel, T. A., 3579Kuo, W-L., 3677

Le Beau, M. M., 3561Lesley, J. F., 3736Levrero, M., 3566Lhuillery, C., 3529Li, Y., 3538Limoli, C. L., 3712Ling, Y-H., 3633

Liu, J. M., 3538Ljung, B-M, 3677Loda, M., 3732Lott, S. T., 3533Lovell, M., 3533Lu, Y., 3677Lutz, M. P., 3551Luu, H. H., 3561

Mancuso, T., 3654Manjeshwar, S., 3677

Maruyama, K., 3526Matsuno, Y., 3700Mazière, J-C, 3571Medh, R. D., 3684Melki, J. R., 3508Miyoshi, Y., 3499Mohler, J. L., 3603Moore, D., 3555, 3677Morgan, W. F., 3712Morlière, P., 3571Morton, C. L., 3627Moy, E. L., 3508

Nadeau, J. H., 3694Nagata, M., 3499Nagura, H., 3491Naito, Y., 3491Nakamura, Y., 3499Nauta, L. E., 3542Naylor, S. L., 3533Neumann, A. A., 3508Nicholson, J. C., 3668Nisen, P. D., 3504Noble, J. R., 3508Noguchi, M., 3700Nozawa, S., 3526

Ohtani, H., 3491Ohuchi, A., 3491Ortiz, N., 3668Otsuki, T., 3538Ozaki, K., 3499Özören,N., 3513

Pagano, S., 3566Pai, S. I., 3513Pang, D., 3495Parodi, S., 3654Pastan, I., 3649Paulson, D., 3603Pegram, M. Y., 3668Perantoni, A. O., 3590Perez-Soler, R., 3633

Pescarolo, M. P., 3654Peyrat, M-B., 3529

Potter, P. M., 3627Prinsep, M. R., 3571Puri, R. K., 3649

Raleigh, J. A., 3547Ramljak, D., 3590Reddel, R. R., 3508Reeder, J. A., 3719Reisfeld, R. A., 3743Rinker-Schaeffer, C. W., 3561

Risinger, J. I., 3579Robbins, P. F., 3519Robertson, C., 3603Rosenberg, S. A., 3519Rosenthal, D., 3495Russo, P., 3654

Sacré-Salem,B., 3529Saeed, M. F., 3684Saigenji, K., 3491Saito, K., 3491Sakamoto, M., 3526Salmona, M., 3654Salzmann, J-L., 3529

Santus, R., 3571Sauter, G., 3555Schönberg, S. O., 3598Schwarzbauer, J. E., 3586Shephard, L., 3712

Shiiba, K., 3491Shultz, K. L., 3694Sidransky, D., 3513Simbulan-Rosenthal, C., 3495

Singh, B., 3633Smith, C. D., 3571Smith, H. S., 3677Smith, R. C., 3561Smulson, M. E., 3495Spoonde, A., 3495Steinberg, M. S., 3586Stephens, E., 3603Stobbe, C. C., 3571Strome, S., 3668Strongin, A., 3743Suzuki, M., 3499Sy, M-S., 3660

Sytkowski, A. J., 3732

Takahashi, E-i., 3499

Takao, S., 3727Takei, K., 3700Takita, J., 3700Taylor, J. A., 3603Tennent, B. J., 3694Thompson, E. B., 3684Tillotson, L. G., 3706Tornos, C., 3633Torres, K., 3620Tsuda, H., 3526Tsukamoto, A., 3751

Ueda, K., 3499Uemura, K., 3727Uezato, H., 3700Umar, A., 3579Umbach, D. M., 3603

Vaisman, A., 3579van Kaick, G., 3598Van Waes, C., 3668Varchenko, M., 3579Vaupel, P., 3598Vikhanskaya, F., 3654

Waldman, F. M., 3555Walsh, A. H., 3611Walsh, M. D., 3719Wang, J., 3538Wang, R-F., 3519Wang, X., 3519Warshaw, A. L., 3706Watabe, K., 3561Wei, M. X., 3529Weikel, W., 3598Wernick, M., 3677Wierdl, M., 3627Willingham, T., 3504Wolverton, J. S., 3627Wu, G. S., 3513Wu, L., 3513

Yakovlev, A., 3495Yang, C-r., 3712Yang, M., 3732Yang, Y., 3633Yokota, J., 3700Yoshida, T., 3751Youssoufian, H., 3538Yu, J., 3538

Zagaja. G. P., 3561Zeng, G., 3519Zuna, L, 3598Zuo, Z., 3611

3760

AMERICAN ASSOCIATION FOR CANCER RESEARCH

GUIDELINES FOR APPLICATION FOR ACTIVE ANDCORRESPONDING MEMBERSHIP

BENEFITS OF MEMBERSHIP

The American Association for Cancer Research (AACR), a scientificsociety of over 13,500 laboratory and clinical cancer researchers, was foundedin 1907 to facilitate communication and dissemination of knowledge amongscientists and others dedicated to the cancer problem; to foster research incancer and related biomédicalsciences; to encourage the presentation anddiscussion of new and important observations in the field; to foster publiceducation, science education, and training; and to advance the understandingof cancer etiology, prevention, diagnosis, and treatment throughout the world.

Members of the AACR enjoy the following benefits:

1. the privilege of sponsoring a proffered paper (abstract) for consideration for presentation at the AACR annual meeting;

2. subscriptions to the Association's high-quality journals Cancer Re

search, Clinical Cancer Research, Cell Growth & Differentiation, andCancer Epidemiology, Biomarkers & Prevention at reduced memberrates;

3. an advance copy of the Program and Proceedings of the AmericanAssociation for Cancer Research that contains over 4,000 abstracts ofproffered papers presented at the annual meeting;

4. reduced registration rates at annual meetings;5. priority notice of small, focussed meetings in the AACR's exciting series

of Special Conferences in Cancer Research;6. substantially reduced registration rates for Special Conferences;7. opportunities for participation in AACR meetings in North America and

abroad with other scientific societies around the world;8. receipt of AACR Newsletters and other important announcements;9. early notification of and reduced rates for participation in the AACR

Employment Register;10. an up-to-date Membership Directory of over 13,500 member researchers

in the cancer field;11. the professional benefits of the AACR's public education activities con

cerning funding for cancer research and press coverage of the latestresearch findings;

12. the opportunity to participate in three Summer Workshops that fosterknowledge in the cancer field for young investigators;

13. the facilitation of informal scientific exchange with leading researchers inthe cancer field; and

14. many more ongoing benefits.

QUALIFICATIONS FOR MEMBERSHIP

Active membership in the AACR is open to investigators who live in theAmericas. Individuals who have conducted two years of research resulting inpeer-reviewed publications relevant to cancer, or who have made substantialcontributions to cancer research in an administrative or educational capacity,are eligible. If a candidate has conducted research in an area of biomédicalscience related to cancer, he or she will qualify for membership. Evidence ofpatents relevant to cancer research may be submitted as qualifications formembership in lieu of peer-reviewed publications.

Corresponding membership is open to persons who are not residentsof the Americas. The qualifications for corresponding membership are thesame as those indicated above for active membership. Visiting scientistsfrom outside the Americas who intend to return to their countries of originby the anticipated time of election should apply for corresponding membership. All other visiting scientists should apply for active membershipand transfer to corresponding status upon leaving the Americas.

Graduate and medical students, postdoctoral fellows, and physicians intraining who do not yet meet the above qualifications for active orcorresponding membership should apply for associate membership.Forms for associate membership are available from the AACR Office.

PROCEDURES FOR APPLICATION

There are three deadlines for the receipt of a membership application:January 1, May 1, and September 1 of each year. The MembershipCommittee will review all complete applications for active membershipthat have been received by these deadlines and will submit recommendations on each candidate to the Board of Directors which formally elects all

members. The same procedure is followed by the Special MembershipsCommittee which receives applications for corresponding membership.Candidates will be notified according to the following schedule:

Receipt of Applicationin AACR Office Notification of Candidate

January 1May 1September 1

MarchJulyNovember

A complete application consists of the following material:1. 6 copies of the form on the opposite side of this page, with all requested

information provided.2. 5 copies of the candidate's most current curriculum vitae and bibliog

raphy.3. 5 copies of a letter of recommendation from a nominator who is an

active, corresponding, emeritus, or honorary member of the AACR (atleast one copy must be a signed, original letter). This letter shoulddescribe the candidate's achievements in laboratory research, clinical

investigations, or epidemiological research, and it should affirm thatthis research adheres to accepted ethical scientific standards. -OR- Thenominator may supply the responses requested at the bottom of theapplication form in the section entitled "STATEMENT OF SUPPORT" (at least one copy of the form must be the signed original).

4. 5 copies of a letter of recommendation as described in Item 3 abovefrom a seconder who is an active, corresponding, emeritus, or honorarymember of the AACR (at least one copy must be a signed, originalletter). -OR- The seconder may supply the responses requested at thebottom of the application form in the section entitled "STATEMENT OFSUPPORT" (at least one copy of the form must be the signed original).

5. 5 reprints of each of two publications on which the candidate appears asauthor. As noted above, evidence of patents developed by the candidatemay be submitted in lieu of one or both of the publications. If submittingpatents, supply patent number and year awarded.

All material should be collated into five complete sets with the originalapplication form as a covering document and sent to the address givenbelow. Questions regarding procedures for membership application mayalso be directed to the following address:

Membership Services DepartmentAmerican Association for Cancer Research

Public Ledger Building, Suite 826150 S. Independence Mall WestPhiladelphia, PA 19106-3483

Phone: 215/440-9300FAX: 215/440-9412

E-mail: aacr@aacr.org

RESPONSIBILITIES OF MEMBERSHIP

Candidates should be aware of the following responsibilities of membership in the AACR. Active members must pay annual dues. In 1998annual dues for active members are $175, $100 of which is designated forAACR journal subscriptions. Newly elected members of the AACR whohave already purchased subscriptions to Cancer Research, Clinical Cancer Research, Cell Growth & Differentiation, or Cancer Epidemiology,Biomarkers & Prevention at the higher, nonmember rates will receivereimbursement of the unused portion of those subscriptions once their firstyear's membership dues are paid in full.

Corresponding members are required to pay dues ($100 in 1998) andmay, if they wish, subscribe to Cancer Research, Clinical Cancer Research, Cell Growth & Differentiation, or Cancer Epidemiology, Biomarkers & Prevention at reduced member rates.

Applicants elected in March will be responsible for payment of thatyear's dues; applicants elected in July and November will pay dues for the

following year. Applicants elected in March and July will be eligible tosponsor an abstract for the next annual meeting. Every effort will be madeto afford the same opportunity to applicants elected in November.

Margaret Foti, Ph.D.Executive Director

AMERICAN ASSOCIATION FOR CANCER RESEARCH, INC.Public Ledger Building •¿�Suite 826 •¿�150 S. Independence Mall West •¿�Philadelphia, PA 19106-3483

APPLICATION FOR ACTIVE OR CORRESPONDING MEMBERSHIP

NAME OF CANDIDATE:. DATE OF BIRTH:.LAST FIRST M.I. Month/Day/Year

PRESENT POSITION/TITLE:

INSTITUTIONALAFFILIATION:INSTITUTIONAL

ADDRESS:(City)

(State/Province)

TELEPHONE NUMBER:(Country)

(Postal Code)

FAXNUMBER:E-MAIL

ADDRESS:

PRIMARY FIELD OF RESEARCH (Please check only one):Biochemistry and Biophysics BiostatisticsCellular Biology and Genetics Clinical Investigationsipidemiology Immunology

eclinical Pharmacology and VirologyExperimental Therapeutics

ACADEMIC DEGREES (Including where and when granted)

_CarcinogenesisSndocrinologylolecular Biology and Genetics

.Other:(Please specify)

EXPERIENCE SINCE HIGHEST DEGREE WAS GRANTED (Please list most recent first)

PUBLICATIONS (Reprints of two peer-reviewed articles on which the candidate appears as an author must accompany this application. Forthese two articles list the authors, title, journal, volume, inclusive pages, and year. Do not submit abstracts. If submitting patents, supply patentnumber and year awarded.)

CANDIDATE IS APPLYING FOR (Check one): D ACTIVE D CORRESPONDING MEMBERSHIP

CANDIDATENOMINATED BY*:.

CANDIDATESECONDED BY*:.

(Please print) (Please print)

STATEMENT OF SUPPORTInstead of submitting letters of recommendation, either the nominator or the seconder or both may complete the following section:

I acknowledge by signing this statement of support that this candidate adheres to accepted ethical scientific standards and has or will make along-term contribution to cancer research.

Signature of Nominator* Date Signature of Seconder*

See Guidelines for Application on the reverse side of this form for further instructions.

*Both nominator and seconder must be active, corresponding, emeritus, or honorary members of the AACR in good standing.

(This form may be reproduced.)

Date

1998

AMERICAN ASSOCIATION FOR CANCER RESEARCH

GUIDELINES FOR APPLICATION FOR ASSOCIATE MEMBERSHIP

QUALIFICATIONS FOR MEMBERSHIP

Associate membership is open to graduate students, medical students,postdoctoral fellows, and physicians in training who are following acourse of study or who are working in a research program relevant tocancer. Scientists in training who already have a substantial record ofpublications may wish to apply for active or corresponding membershipwhich confers full benefits of membership.

BENEFITS OF MEMBERSHIP

The American Association for Cancer Research (AACR), a scientificsociety consisting of laboratory and clinical cancer researchers, wasfounded in 1907 to facilitate communication and dissemination of knowledge among scientists and others dedicated to the cancer problem; tofoster research in cancer and related biomédicalsciences; to encouragepresentation and discussion of new and important observations in thefield; to foster public education, science education, and training; and toadvance the understanding of cancer etiology, prevention, diagnosis, andtreatment throughout the world. Associate members of the AACR enjoythe following benefits:

1. the privilege of sponsoring a proffered paper (abstract) for consideration for presentation at the AACR annual meeting provided that (a)the associate member is the presenter of the paper and (b) an active,corresponding, emeritus, or honorary member in good standing of theAACR also signs the abstract of the paper in support of the work. (Inthis instance, the member who cosigns the abstract does not lose hisor her own sponsorship privilege.);

2. optional subscriptions to the Association's high-quality journals:

Cancer Research, Clinical Cancer Research, Cell Growth & Differentiation, and Cancer Epidemiology, Biomarkers & Prevention atreduced member rates; beginning in 1998 associate members will beable to purchase AACR journals for half the price of a regularmember subscription;

3. the privilege of registering for the annual meeting at the low associatemember rate;

4. the privilege of electing an Associate Member Council that organizesprograms benefiting associate members and that presents their concerns to the AACR Board of Directors;

5. the opportunity to stand for election to the Associate Member Council;

6. preferred access to the AACR Employment Register;7. priority notification of events in the AACR's series of special

conferences on timely subjects in the field;8. substantially reduced registration rates at special conferences;9. the receipt of AACR newsletters, meeting announcements, and an

up-to-date Membership Directory;10. the opportunity to participate in three Summer Workshops that foster

knowledge in the cancer field for young investigators; and11. the facilitation of informal scientific exchange with leading research

ers in the cancer field.

PROCEDURES FOR APPLICATION

Persons wishing to apply for associate membership must use theofficial application form on the reverse side of these instructions. Eachcandidate for associate membership must be nominated by an active,corresponding, emeritus, or honorary member in good standing of the

AACR. Three completed copies of the form should be submitted; at leastone of these copies must carry the original signatures of both the candidateand the nominator. In addition, the candidate should submit one copy ofhis or her curriculum vitae. The application form may be submitted to theAssociation Office at any time.

After review of applications for associate membership, the ExecutiveDirector will notify candidates of their election or deferral within onemonth of the receipt of the application form. A check for one year's dues

payment must accompany the application. Dues for 1998 are $55 forassociate members residing in the Americas and $65 for residents of othercountries. This fee will be refunded to any candidate deemed to beineligible for associate membership. Checks should be in U.S. currency,made payable to AACR, Inc., and drawn on a U.S. bank. Send the threecopies of the application form and the appropriate dues payment to:

Membership Services DepartmentAmerican Association for Cancer Research

Public Ledger Building, Suite 826150 S. Independence Mall WestPhiladelphia, PA 19106-3483

Phone: 215/440-9300Fax: 215/440-9412

E-mail: aacr@aacr.org

RESPONSIBILITIES OF MEMBERSHIP

Associate members must pay annual dues in an amount to be determined by the AACR Board of Directors. Dues for 1998 have been set at$55 per year for residents of the Americas and $65 for residents of othercountries. If an application is submitted by August 31, the accompanyingdues payment will be credited to the current year. Candidates submittingapplications between September 1 and December 31 may indicate whetherthey wish their dues payments credited to the current or forthcoming year.Candidates should be aware, however, that associate members may sponsor an abstract for the annual meeting only if their dues for the current yearare paid. For example, an associate member submitting an abstract inNovember 1998 for the forthcoming annual meeting must have paid duesfor 1998. Any newly elected associate members of the AACR who havealready purchased subscriptions to Cancer Research, Clinical CancerResearch, Cell Growth & Differentiation, or Cancer Epidemiology, Bio-markers & Prevention at the higher, nonmember rate will receive a refundfor the unused portion of that subscription upon receipt of their paymentfor a member's subscription.

Each Fall the AACR will send to current associate members an invoicefor dues for the forthcoming year. Payment of this invoice must beaccompanied by a statement signed by the associate member's currentregistrar, dean, or department head, verifying the member's current academic status. The Association's By-Laws state that dues are payable for

each year in advance by January 1 of the year to which they should beapplied. An individual may be an associate member for a maximum offive years. Each year in which an individual pays dues will count as onefull year of associate membership. Thus, an associate member who paysdues for 1998 may retain associate membership until December 31, 2002.The Board of Directors may terminate the membership of an associatemember whose dues are in arrears for two years.

Margaret Foti, Ph.D.Executive Director

AMERICAN ASSOCIATION FOR CANCER RESEARCH, INC.Public Ledger Building •¿�Suite 826 •¿�150 S. Independence Mall West •¿�Philadelphia, PA 19106-3483

APPLICATION FOR ASSOCIATE MEMBERSHIP

NAME OF CANDIDATE:. DATE OF BIRTH:.LAST FIRST M.I. Month/Day/Year

INSTITUTIONAL AFFILIATION:.

INSTITUTIONAL ADDRESS:

(City)

TELEPHONE NUMBER:.

E-MAIL ADDRESS:

(State/Province) (Country)

FAX NUMBER:.

(Postal Code)

PRESENT ACADEMIC STATUS/TITLE (Please check only one):Graduate Student Medical StudentPhysician in Training Postdoctoral Fellow

PRIMARY FIELD OF RESEARCH (Please check only one):Biochemistry and Biophysics BiostatisticsCellular Biology and Genetics Clinical Investigationsipidemiology Immunologytechnical Pharmacology and Virology

Experimental Therapeutics

Gender: D Male D Female

.Carcinogenesisndocrinologylolecular Biology and Genetics

.Other:(Please specify)

ACADEMIC DEGREES (Please indicate degree(s) acquired to date along with the name of the academic institution and date of receipt. Provideinformation on degree currently being sought and the anticipated date of completion of this degree program.)

RELEVANT RESEARCH EXPERIENCE NOT RELATED TO COURSE WORK (Please list most recent first.)

PUBLICATIONS (List the authors, title, journal, volume, inclusive pages, and year of any article in a peer-reviewed journal on which the

candidate appears as an author. Do not list abstracts. Continue on a separate sheet, if necessary.)

CANDIDATE NOMINATED BY*:

(Please print)SIGNATURESI hereby apply for associate membership in the American Association for Cancer Research. I have read the instructions on the reverse side ofthis form, and I understand the privileges and responsibilities of this class of membership. I certify that the statements on this application aretrue.

Signature of Candidate: Date:

I recommend this candidate for associate membership in the American Association for Cancer Research. To the best of my knowledge, thecandidate is qualified for this class of membership, and the statements on this application are true.

Signature of Nominator*: Date:

Submit three copies of this form. At least one copy must contain the original signatures of the candidate and the nominator. In addition, submitone copy of your curriculum vitae. Enclose a check in U.S. funds, made payable to AACR, Inc., and drawn on a U.S. bank for one year's dues.

For 1998, dues are $55 for associate members residing in the Americas and $65 for residents of other countries.

Check one of the following boxes only if this form is being submitted between September 1 and December 31:The enclosed dues payment should be applied to the D current D forthcoming calendar year.

(NOTE: If dues are applied to the forthcoming year, membership will take effect on January 1, but the candidate will not be eligible to sponsoran abstract for presentation at the annual meeting in March or April of that year.) See Guidelines for Application on the reverse side of thisform for further instructions.

*Nominator must be active, corresponding, emeritus, or honorary member of the AACR in good standing.

(This form may be reproduced.) 1998

Guidelines for Submitting Disksto

American Association for Cancer Research Publications

The word processing packages that we prefer are as follows:

MacWriteMicrosoft Word (DOS, Windows,

and Macintosh)

WordPerfect (DOS, Windows,and Macintosh)

XyWrite (DOS and Windows)

Also acceptable:

AbilityAmiProA.S-TEXAppleworksArborTEXArborTextClarisWorks WPCPT 8000CTOSDiabloDisplayWriteDuetEinsteinEnableEXPFinal WordFullWriteGemWord PlusIBM Writing AssistantInterleafLATEX

LatexLeading EdgeLotus ManuscriptLotus Write

Mass 11MS Windows WriteMS WorksMS Works WP MacMultimateMultimate AdvantageNibiaNisus (to ASCII file)NotewriterObunOfficeWriterPC WritePFS First ChoiceProfessional WriteQ&A WriteQuark XPressRagTime MS Works

(to ASCII file)Rich Text FormatRSG (to ASCII file)SignatureSLITEXSmartWhereSmartWrite II

SoloWriterSprintStxSunWriteSymphonyTEXTEX78Text ExecutiveTexturesTotal WordTroff/¿TEXVolkswriterVuWriterWang OISWang WPSWang WriterWindow WorksWindows WriteWiziWordWordstarWordstar 2000WriteNowXerox

Software packages that we are unable to translate:

FrameMakerPageMaker

Ready, Set, GoScientific Writer

Disks produced on IBM or IBM-compatible computers are preferred, but those produced on some Apple orWang computers can also be converted. Because of the file structures and internal coding, we cannot acceptdisks created on desktop publishing systems or those created on proprietary typesetting systems. We alsocannot guarantee that all special characters can be translated. Tabular and mathematical material, such asequations, will not be captured from the disk but will be rekeyed.

To expedite work and for your own security, we do require that you submit a hard copy printout of the diskfile. The tables and equations will be keyed from this hard copy. We also need to know the name of the fileto be converted, the type of hardware (e.g., IBM PC) on which the files were created, the operating system(e.g., DOS 3.3), and the version of the software (e.g., WordPerfect 5.1) used to create the file.

PLEASE FILL OUT ALL INFORMATION ON REVERSE SIDE AND SUBMIT THIS FORM WITH YOUR DISK.DISKS WILL NOT BE PROCESSED WITHOUT THIS INFORMATION.

DISK SUBMISSION FORM

AACR journals are now using personal computers to copyedit manuscripts accepted for publication. Whensubmitting a revised manuscript, authors are encouraged to submit an electronic disk of the paper along withthe required four hard copy printouts. Disks will ultimately be returned to the authors.

See reverse for the word processing packages that can be accepted.

File preparation

Please be sure that the file you send is the most recent version of the manuscript and that it matches the mostrecently submitted printed copy. The file should contain all the parts of the manuscript in one file. Mathematical and tabular material, however, will be processed in the traditional manner and may be excluded fromthe disk file.

Note: AACR does not assume responsibility for errors in conversion of customized software, newly releasedsoftware, or special characters.

Please label the outside of the disk with the journal name, the first author's name, a partial title of the

manuscript, and the name of the computer file used to access the manuscript on disk. To process your diskefficiently, we need the following information. Please be sure to provide ALL the information.

Name used to access paper on disk:Name of computer used (e.g., IBM/PS2):Operating system and version (e.g., DOS 3.3):Word processing program and version (e.g., WordPerfect 5.0):

[See reverse for acceptable programs.]

Manuscript number:First author:Corresponding author (if different from first author):Telephone/FAX numbers:

This form (both sides) may be reproduced.

AACR SPECIALCONFERENCE INCANCER RESEARCH

NewResearchApproachesinthe Preventionand Cureof

ProstateCancerDecember2-6,1998

HyattGrandChampionsResortIndianWells(PalmSprings),CA

Supportedby MajorEducationalGrantsfromBristol-MyersSquibbOncologyand from

BeckmannCoulter,Inc.

CONFERENCE CO-CHAIRPERSONS

Jonathan W. Simons / Baltimore,MDKenneth J. Pienta / Ann Arbor, Ml

CONFERENCE PROGRAM

KeynoteAddressesAndyGrove/ SantaClara,CALeroyE.Hood/Seattle,WADonaldS.Coffey/ Baltimore,MD

Heredity and EnvironmentElaineA. Ostrander/ Seattle,WAWilliamB. Isaacs/ Baltimore,MDWilliamG.Nelson/ Baltimore,MDTheodoreL. DeWeese/ Baltimore,MDOtisW.Brawley/ Bethesda,MD

Local Control of Clinical Prostate CancerJeffreyD.Forman/ Detroit,MlCurtisA. Pettaway/ Houston,TX

Molecular PathologyLanceA. Liotta/ Bethesda,MDJill A. Macoska/ AnnArbor,MlRobertE.Reiter/ LosAngeles,CA

Hormones and Hormone TherapyEvelynR.Barrack/ Baltimore,MDRonaldM.Evans/ LaJolla,CAMartinE.Cleave/ Vancouver,BC,CanadaJuneM.Chan/ Boston,MA

Prostate Cancer Tumor BiologyCarrieW.Rinker-Schaeffer/ Chicago,ILNormanM.Greenberg/ Houston,TXRobertS.Kerbel/ Toronto,Ontario,Canada

NewTherapeuticInitiativesfor AdvancedDiseaseStuartHolden/ SantaMonica,CARobertE.Wittes/ Bethesda,MDErkkiRuoslahti/ LaJolla,CAJonathanW.Simons/ Baltimore,MDNealRosen/ NewYork,NY

Growth FactorsWallaceL. McKeehan/ Houston,TXMichaelO'Reilly/ Boston,MA

RobertH.Getzenberg/ Pittsburgh,PARonaldA. Morton,Jr. / Houston,TX

Novel Therapeutic StrategiesKennethJ. Pienta/ AnnArbor,MlGeraldP.Murphy/ Seattle,WAMartinG.Sanda/ AnnArbor,MlAlanW.Partin/ Baltimore,MD

Additional Talks from Selected AbstractsSubmitted by Young Investigators

Registration Deadline: September 28, 1998Information and Application Forms:American Association for Cancer ResearchPublic Ledger Building, Suite 826150 South Independence Mall WestPhiladelphia, PA 19106-3483215-440-9300 215-440-9313 (FAX)E-mail: meetings@aacr.orgWebsite: http://www.aacr.org

AMERICAN ASSOCIATION FOR CANCER RESEARCHResearch Grants for Young Cancer Scientists

New! Application forms available on-line at http://www.aacr.org

GERTRUDE B. ELION CANCER RESEARCH AWARDSupported by an Educational Grant from Glaxo Wellcome Oncology

The Gertrude B. Elion Cancer Research Award is a one-year, $30,000 grant for a scientist in the U.S. or Canada

engaged in meritorious basic, clinical, or translational research in cancer etiology, diagnosis, treatment, orprevention at the level of Assistant Professor (not yet tenured). The AACR will reimburse the Awardee for travelto the 1999 Annual Meeting in Philadelphia, PA, where Dr. Elion will personally present this Award.

Eligibility/Selection ProcessCandidates must have completed postdoctoral studies or clinical fellowships not later than July 1 of the Awardyear, and ordinarily not more than five years earlier. Tenured faculty in academia, federal governmentemployees, and employees of private industry are not eligible for this award. A Candidate need not be a memberof the AACR at the time of application, but must be nominated by a Member of the AACR. Associate Membersmay not be nominators. Applications are evaluated by a Committee consisting of AACR Members who areexperts in basic, clinical, translational, and prevention research. Application deadline: December 15,1998.

AACR RESEARCH FELLOWSHIPSFor Young Scientists at the Postdoctoral or Clinical Fellow Level

New! Some Two-Year Fellowships

The AACR Research Fellowships in Clinical, Translational, Basic, and Prevention Research foster meritoriouscancer research in North, Central, or South America by young scientists currently at the postdoctoral or clinicalresearch fellow level. Sponsored by Amgen, Bristol-Myers Squibb Oncology, Cancer Research Foundation ofAmerica, the Sidney Kimmel Foundation for Cancer Research, AACR, and others, the AACR Fellowshipsprovide either one or two years of salary support at the rate of $30,000 per annum. Those awarded two-yeargrants who receive a junior faculty appointment in the second year may use the funds for non-salary researchexpenses in connection with the new position.

Eligibility/Selection ProcessCandidates must have completed the M.D., Ph.D., or other doctoral degree. Candidates must currently be apostdoctoral or clinical research fellow and must have been a fellow for at least two years but not more than fiveyears prior to the year of the award. Academic faculty, graduate or medical students, medical residents, permanentgovernment employees, employees of private industry, and individuals who will receive fellowships from similarprograms during the award year are not eligible. A candidate need not be a member of the AACR at the time ofapplication, but he or she must be nominated by an AACR Member, and non-members must submit an acceptable

application for membership with the fellowship application. Associate Members may not be nominators.Applications are evaluated by a Committee consisting of AACR Members who are experts in basic, clinical,translational, and prevention research. Application deadline: January 15,1999.

For Further InformationAMERICAN ASSOCIATION FOR CANCER RESEARCH

Public Ledger Building, Suite 826150 South Independence Mall West

Philadelphia, PA 19106-3483Telephone: (215)440-9300 FAX: (215)440-9372 E-mail: horst@aacr.org

1999 AACR-Pezcoller International Awardfor Cancer Research

FondazionePKZCOI.LKRTrento - Italy

AACR-Pezcoller International Award Committee

Peter K. Vogt, Ph.D., Chairperson, Scripps Research Institute, La Jolla, USAFranco Cavalli, M.D., Ospedale San Giovanni, Bellinzona, Switzerland

Gertrude B. Elion, D.Sc., Glaxo Wellcome, Inc., Research Triangle Park, USARichard D. Kolodner, Ph.D., Ludwig Institute for Cancer Research, La Jolla, USA

Alex Matter, M.D., Novartis Pharma AG, Basel, SwitzerlandMarco A. Pierotti, Ph.D., Istituto Nazionale Tumori, Milan, Italy

Masaaki Terada, M.D., D.M.Sc., National Cancer Center Research Institute, Tokyo, JapanBengt Westermark, Ph.D., University of Uppsala, Uppsala, Sweden

Ex officioDavid M. Livingston, M.D., Dana-Farber Cancer Institute, Boston, USA

Enrico Mihich, M.D., Roswell Park Cancer Institute, Buffalo, USA

The AACR-Pezcoller International Award for Cancer Research isgiven annually to a scientist who has made a major scientificdiscovery in the field of cancer, who continues to be active in thefield, and whose ongoing work holds promise for future contributions to cancer research. The Pezcoller Foundation wasestablished in 1982 by Professor Alessio Pezcoller, a dedicatedItalian surgeon who has made important contributions tomedicine during his career and who, through his foresight, vision,and generous gift in support of the formation of the Foundation,stimulated others to make significant advances in cancerresearch. Over the past decade the Pezcoller Foundation hasgiven a major award for outstanding contributions to cancer andcancer-related biomedicai science.

The American Association for Cancer Research (AACR) wasfounded in 1907 by eleven physicians and scientists dedicated tothe conquest of cancer and now has nearly 14,000 members inmore than 60 countries who are experts in basic, clinical, andtranslational cancer research. The mission of the AACR is tofoster cancer research; this is accomplished in part through outstanding scientific publications, meetings, and training andeducational programs. Because of the commitment of theFoundation and the AACR to scientific excellence in cancerresearch, these two organizations are collaborating annually onthe presentation of the AACR-Pezcoller Award. This jointlysponsored award will strengthen international collaborations andwill be a catalyst for advancements in cancer researchinternationally. The awardee will be selected by an internationalcommittee of AACR members appointed by the AACR Presidentalong with the agreement of the Council of the PezcollerFoundation. While normally the Award will be presented to asingle investigator, in exceptional cases two individuals may beselected to share the award when their investigations haveresulted in related prizeworthy work. The committee will makeits selection solely on the basis of the awardee's scientific

accomplishments without regard to race, gender, nationality, orreligious or political views. The candidate will give an awardlecture during the AACR Annual Meeting in Philadelphia, USA(April 10-14, 1999) and will receive the award in an officialceremony at the Foundation's headquarters in Trento, Italy, after

the annual meeting. The award consists of an honorarium ofUS$75,000 and a commemorative plaque.

The Pezcoller Foundation and the AACR are now solicitingnominations for the 1999 Award. Nominations can be made byany scientist who is now or has been affiliated with an institutionengaged in cancer research. Institutions or organizations are noteligible for this award, and candidates may not nominatethemselves.

There is no official application form for this award,nomination package should consist of the following:

The

•¿�the candidate's curriculum vitae and full list of published

works

•¿�an indication of the candidatesi most importantpublications

•¿�a letter of recommendation in English (500 words,maximum) explaining why the candidate is deserving ofthis prestigious Award. This letter should summarize thecandidate's major scientific achievements, indicate which ofthe candidate's publications best describe these

achievements, and explain the impact of these achievementson progress in cancer research.

Nominators are asked to maintain the confidentiality of thenomination process and to refrain from informing the candidateabout the nomination.

The deadline for receipt of nominations for the 1999 Award isOctober 1, 1998. Questions about the nomination processshould be directed to the AACR via FAX at (215) 440-9322 orE-mail at aacr@aacr.org. Nominations should be submitted to

the AACR. Please forward the original nomination letter plus 15copies of the letter and any accompanying materials to:

Peter K. Vogt, Ph.D., Chairperson, Selection CommitteeAACR-Pezcoller International Award for Cancer Research

c/o American Association for Cancer ResearchPublic Ledger Building, Suite 826

150 S. Independence Mall WestPhiladelphia, PA 19106-3483

USA

Thewaytosilenceakiller

istomake

Cancer kills more than 1,500 people everyday. And it is theleading cause of death by disease in our children. Yet, forevery ten dollars in taxes the government collects, it spendsonly ariepennyon cancer research. We can do better. For themore than eight million Americans now living with cancer -and for the millions more at risk - we must do better. THE

MARCH is a momentous event uniting people inWashington, DC, and in communities across the nation.We are coming together to make cancer the nation's # 1

research priority. We are raising our voices to say Nomore... No more suffering... No more excuses... No morecancer. Please join us.

ATHE

Coming Together To Conquer CancerSM

September 25 & 26, 1998

1730 K Street, 4th FloorWashington, DC 20006

I.877.THE.MARCHwww.thcmarch.org

THE SIDNEY KIMMEL FOUNDATION/or CANCER RESEARCH

The AACR is a proud supporter of The March. For information about AACR members'

March-related activities, please call the AACR Office at (215) 440-9300.