Annual General Meeting 3 July 2018

Asthma UK

Agenda

Presentations

▪ Review of 2016 – 17

▪ Digital Health

▪ Individual Giving

▪ Financial review

Formal AGM business

▪ Apologies

▪ Minutes from 2017 AGM

▪ Annual Report

▪ Auditors

▪ Trustees

Highlights of 2016 - 17

Kay BoycottChief Executive

Our mission: Stop asthma attacks. Cure asthma.

CAMPAIGN FOR CHANGE ON THE ISSUES THAT AFFECT PEOPLE WITH ASTHMA

We constantly challenge complacency around asthma so that everyone knows just how serious asthma is

We campaign and raise awareness of the issues and solutions so everyone gets the right basic care that

research has proved substantially reduces the risk of an asthma attack

We help people with asthma speak directly to politicians and decision makers on the issues that are important to

them

FUND WORLD-CLASS RESEARCH

We have invested over £50 million in asthma research to date We fund scientists to pursue new avenues of research into

asthma and develop better treatmentsNew technologies and better collaboration will increase the chances of scientific breakthroughs. Ultimately a cure that

would transform the lives of people with asthma will be found We are determined that everyone with asthma will benefit

from scientific breakthroughs

PROVIDE EXPERT ADVICE AND SUPPORT

We help people to effectively manage their daily life with asthma

We achieve this by providing access to the best information and practical advice available through our website and our expert asthma nurse helpline

How we are making a difference:In the last year, Asthma UK has…

➢ Supported over 1.8 million users on our website – an increase of 27% from last year➢ Enabled 93,000 Asthma Action Plans to be downloaded – 71,000 of these for adults

and 21,000 for children

➢ Selected as 1 of 4 ‘launch’ charities to use Facebook Pay➢ Made the most from every donation: for every £1 spent…. 31.5p was reinvested in

fundraising to make another £1 and 68.5p was spent on charitable activity

➢ Grown our social media channels by 20% (based year on year) ➢ Engaged with 30,000 Facebook users as part of our ‘back to school campaign’ and our

pollen campaign reached 300,000 on social channels ➢ Helped 7367 people through our helpline whilst our nurses answered 7000 calls….at the

same time as delivering popular asthma Q&A sessions on social media!

➢ Published the Annual Asthma Survey 2017, with 7611 responses – the largest AUK has ever seen!

➢ Successfully campaigned for the use of Mepolizumab and Reslizumab in the NHS➢ Launched our Smart Asthma report as well as the 2016 – 2021 Research Strategy and

the Research Roadmap ➢ Renewed our investment in the Basic Centre for another 5 years➢ Funded 2 Fellows at Imperial College➢ Co-funded £100,000 into the Epigenetics project (in partnership with LifeArc)

Research: ‘stand on the shoulders of giants’

2016 – 17 advances in scientific knowledge (funded through AUK research)

Dr Henry McSorley has uncovered novel means to target a cytokine called IL-33, which is strongly implicated in causing asthma; this discovery promises exciting

new opportunities for intervention in asthma

Dr Anna Furmanski tested the idea of controlling the amount of Hedgehog (Hh) proteins (which cause inflammation in the lungs) to minimise allergic immune responses in asthma; a promising

new idea for potential asthma treatments

Prof. Ian Sayers and his team have identified the main genetic changes in the IL-33 and ST-2 genes that are relevant to asthma; paving the way to understanding the changes and

targeting them for therapy to correct the change

Prof. Salman Siddiqui has found different types of asthma pathology using new data analysis techniques, allowing them to separate different types of airways pathology

for people with mild, moderate and severe asthma

Dr Hans Michael Haitchi (researching ADAM-33 a susceptibility gene that is associated with asthma) and his team have studied the effects caused by changes in ADAM-33 very early in life; leading to discoveries about the

ways in which airways are prone to developing asthma when exposed to house dust mite allergen, at a very early stage in life

2016 – 17 advances in scientific knowledge (funded through AUK research)

Dr Rachel Clifford has identified several genes that are particularly interesting in airway muscle cells & examined these for changes in DNA and gene signalling

Dr Amanda Tatler and the team have developed methods to perform key experiments on human tissue to compare responses between asthmatic and non-asthmatic breathing

Prof. Hannah Gould and her team compared the gene expression signatures (which genes are ‘on’ and which are ‘off’) of cells that produce IgE antibodies; leading to potential new discoveries for targeting

intervention in the development and progression of asthma

Dr Tara Sutherland has succeeded in establishing a ‘mouse model’ of allergic inflammation and the factors assumed to play a role in humans; future work will

look at changes in lung structure

Dr Hannah Durrington has continued her work on understanding why asthma varies so much over the course of a day, this data has been presented as a talk at the European Biological

Rhythms Society meeting (July 2017)

Prof. Andrew Wardlaw and his Asthma UK funded PhD student have continued their work exploring the relationship between fungal allergy and lung damage. Their results could have

major implications for treating fungal allergy in asthma

Delivering charitable purpose Managing resources responsibly

Activity 2017 – 2020 Strategy Activity 2017 – 2020 Strategy

Improve asthma management

wherever delivered

Inspire people with asthma to make a positive change

Maximiseresources for the

long-term benefit of

people with asthma

Develop a sustainable asthma income generation model for a

digital world

Re-imagine asthma self-management through

digital innovation

Pursue improvement in the NHS for people with asthma

Speed up research against

the biggest asthma priorities

Broker ambitious research collaborations Advance Asthma UK’s agility and

productivityInvest in exceptional patient-centric science

Asthma UK 2017 – 2020: strategy

Digital health

Emma RubachAdvice & Content Manager, Digital Health

Our risk checker engaged new people

Cross-selling the risk checker with our lottery audience has proved successful.

After completing the checker people also have the option to sign up to get more email advice from us.

50% increase in people using the risk checker tool

Social media health activation campaigns

30,000 Facebook users watched our ‘Back to School’ campaign video, warning parents of the spike in asthma attacks in September

Our pollen campaign reached almost 300,000 on social channels

Increasing the reach of our Helpline nurses

Answering people with asthma’s questions on Facebook and Twitter

Supporting people through the pilot of our 12-Week Asthma Support Programme

Appearing on instructional and advice videosThis video on cleaning your

spacer has had 12,600 views on

YouTube

Individual Giving

Joe Aldrich Direct Marketing Manager, Fundraising

INDIVIDUAL GIVING

CASH APPEALS & MAGAZINES

RAFFLES & LOTTERY

REGULAR GIVING

STEWARDSHIP

Raising £1.8M a year

INDIVIDUAL GIVING – Cause led growth

*All figures up to the end of May 18

GROSS INCOME* £1.02M 5% growth year on year

NET INCOME* £831K 9% growth year on year

INDIVIDUAL GIVING – Cause led growth

*All figures up to the end of May 18

2017/18 Gross Income Net Income 2016/17

XMAS APPEAL £48.6K £32.5K 35% net growth year on year

SPRING RAFFLE £44.5K £17K 12% net growth year on year

95%

5%

2016/17

Offline

Online

84%

16%

2017/18

Offline

Online

98%

2%

2015/16

Offline

Online

INDIVIDUAL GIVING – Lottery investment

*All figures up to the end of May 18

GROSS INCOME* £194K 47% growth year on year

NET INCOME* -£190K 900% increase in spend year on year

INDIVIDUAL GIVING – Lottery investment

*All figures up to the end of May 18

£32,000

£77,000

£0 £20,000 £40,000 £60,000 £80,000 £100,000

Online

Phone

Gross Income through acquisition*

1500%

381%

0% 500% 1000% 1500% 2000%

Online

Phone

Income % Increase Year on Year

The future is bright… the future is purple

1

2016 – 17 Financial Performance

Harriet Jones Director of Finance and Resources

Overall financial performance

£000’s 2014-15 2015-16 2016-17

Income 7,973 8,762 7,950

Expenditure 7,496 9,292* 7,139

Surplus/(deficit) 477 (530) 811

Investment gain / (loss) (229) 1,467 315

Net surplus 248 937 1,126

* Includes investment in Asthma UK Centre in Allergic Mechanisms of Asthma

Income

£000’s 2014-15 2015-16 2016-17

Individuals 2,404 2,430 2,108

Companies and Trusts 872 688 710

Community and Events 1,333 1,214 1,347

Legacies 3,059 3,697 3,041

Other Income 305 502 460

Gifts in Kind - 231 284

Total 7,973 8,762 7,950

Income sources (gross)…..

… with costs of fundraising

Spend

£000’s 2014-15 2015-16 2016-17

Research 1,557 3,688 1,496

Improving care 1,312 905 798

Advice and support 2,293 2,507 2,579

Fundraising 2,290 2,171 2,266

Investment management 44 21 -

Total expenditure 7,496 9,292 7,139

* Includes Governance

Reserves

Financial forecast

£000’s 2015-16 2016-17 2017-18

Income 8,762 7,984 8,239

Expenditure 9,292* 7,583 8,463

Surplus/(deficit) (530) 401 (224)

Investment gain / (loss) 1,467 - -

Net surplus/(deficit) 937 401 (224)

* Includes investment in Asthma UK Centre in Allergic Mechanisms of Asthma

AGM Formal Business

John Tucker Chairman

AGM

▪ Formal AGM business ▪ Apologies ▪ Minutes from 2017 AGM▪ Annual Report ▪ Auditors ▪ Trustee election (please be reminded only members can

vote)

End