Conclusion: The coexistence of preprocedural neutrophilia andanemia in patients undergoing PCI for STEMI is an independentpredictor of short-term clinical outcomes.

AS-106Impact of Statins on 12-Month Clinical Outcomes in Patientswith Acute ST-Segment Elevation Myocardial Infarction.Seung-Woon Rha1, Lin Wang1, Kanhaiya L. Poddar1,Sureshkumar Ramasamy1, Byoung Geol Choi1, Ji Bak Kim1,Seung Yong Shin1, Cheol Ung Choi1, Hong Euy Lim1,Jin Won Kim1, Eung Ju Kim1, Chang Gyu Park1, Hong Seog Seo1,Dong Joo Oh1, Young Keun Ahn2, Myung Ho Jeong2,KAMIR Investigators3. 1Korea University Guro Hospital, Seoul,Republic of Korea; 2Chonnam National University Hospital,Gwangju, Republic of Korea; 3Other KAMIR Investigators, Seoul,Republic of Korea.

Background: There are very limited data on the role of statins inmanaging acute ST-segment elevation myocardial infarction (STEMI),especially in the drug-eluting stent (DES) era.

Methods: The study population consisted of 4,304 consecutivepatients with STEMI enrolled in the Korea Acute Myocardial Infarc-tion Registry (KAMIR) study from November 2005 to April 2008. Ofthese patients, 92% underwent percutaneous coronary intervention(PCI) with DES, and the rest of the patients received either a bare-metalstent (BMS) or thrombolysis. Statin types and doses were at thephysician’s discretion, and 3,355 patients were included from the timeof presentation. We investigated the clinical outcomes using propensityscore (PS) adjustment between the 3,355 statin-naive patients and thosewithout statin treatment (n � 949) up to 12 months.

Results: The baseline characteristics were similar between the 2groups, except that patients in the statin group were younger than thosein the no-statin group (age, 61.2 � 12.6 years vs 63.2 � 12.4 years, p�0.05). Mortality, repeat PCI (predominantly derived by fewer non-target vessel revascularizations), recurrent acute MI, and total majoradverse cardiac events (MACE) were significantly lower in the statingroup (Table). Statin administration was associated with a lower inci-dence of MACE at 12 months (unadjusted odds ratio, 0.559; 95%confidence interval, 0.453–0.691; p �0.01; PS-adjusted odds ratio,0.654; 95% confidence interval, 0.505–0.847; p � 0.001).

Conclusion: Routine administration of statins in patients with acuteSTEMI, regardless of the revascularization strategy, showed better12-month clinical outcomes compared with those of STEMI patientswithout statin therapy.

AS-107

Clinical Effects of Distance Between Home and Hospital onMortality in Patients with Acute Myocardial Infarction.Chung Kim, Myung Ho Jeong, Keun-Ho Park, Min Goo Lee,Jum Suk Ko, Doo Sun Sim, Nam Sik Yoon, Hyun Ju Yoon,Young Joon Hong, Hyung Wook Park, Ju Han Kim,Young Keun Ahn, Jeong Gwan Cho, Jong Chun Park,Jung Chaee Kang. Chonnam National University Hospital, Gwangju,Republic of Korea.

Background: The mortality of patients with acute myocardial in-farction (AMI) has been known to increase as the time betweensymptom onset and hospital arrival increases. But the relation ofAMI mortality and the distance between home and hospital is notwell known.

Methods: From November 2005 to December 2007, 1,223 patientswith AMI (age, 63.2 � 12.3 years; 864 men) were classified by thedistance between home and hospital, within 1 hour (group 1, n � 699),1– 2 hours (group 2, n � 315), 2–3 hours (group 3, n � 199), and �3hours (group 4, n � 9). The mortality, success rate of percutaneouscoronary intervention (PCI), and major adverse cardiac events (MACE)at 1 month, 6 months, and 1 year were compared.

Results: Diagnosis of acute ST-segment elevation myocardial in-farction (STEMI) was not different among the 4 groups (65.4% vs65.1% vs 66.8% vs 33.3%, p � 0.233), and clinical characteristics andangiographic findings were not different among the 4 groups. Thesuccess rate of PCI was higher in the near-distance group (93.7% vs91.3% vs 89.8% vs 85.7%, p � 0.042). In patients with STEMI, therewas more primary PCI as the distance decreased (76.1% vs 77.1% vs72.9% vs 66.7%, p � 0.527), and there was a higher rate of in-hospitalmortality as the distance increased (4.4% vs 5.1% vs 5.0% vs 11.1%,p � 0.504). Increasing distance was also associated with higher1-month composite MACE (9.9% vs 11.7% vs 10.2% vs 22.2%, p �0.486), 6-month composite MACE (19.8% vs 23.5% vs 17.3% vs22.2%, p � 0.368), 1-year composite MACE (23.3% vs 26.0%vs 19.5% vs 33.3%, p � 0.337), 1-month mortality (7.0% vs 9.5% vs8.7% vs 22.2%, p � 0.141), and 1-year mortality (10.2% vs 14.3% vs9.7% vs 22.2%, p � 0.171), although these associations were notsignificant.

Conclusion: As the distance between home and hospital becamecloser, patients with AMI had more primary PCI and had highersuccess rates of PCI. Although in-hospital and 1-year total MACE andmortality rates became higher as the distance became longer, theseassociations were not significant.

AS-108

Pitavastatin (Livalo) Versus No Statins in Patients with AcuteMyocardial Infarction Undergoing Percutaneous CoronaryIntervention: 12-Month Clinical Outcomes from the Livalo AcuteMyocardial Infarction Study (LAMIS). Seung-Woon Rha1,Lin Wang1, Ji Young Park1, Kanhaiya L. Poddar1,Sureshkumar Ramasamy1, Byoung Geol Choi1, Ji Bak Kim1,Seung Yong Shin1, Cheol Ung Choi1, Hong Euy Lim1,Jin Won Kim1, Eung Ju Kim1, Chang Gyu Park1, Hong Seog Seo1,Dong Joo Oh1, Young Keun Ahn2, Myung Ho Jeong2,Other LAMIS Investigators3. 2Chonnam National UniversityHospital, Gwangju, Republic of Korea; 3Other LAMIS investigators,Seoul, Republic of Korea; 1Korea University Guro Hospital, Seoul,Republic of Korea.

The American Journal of Cardiology� APRIL 28–30 2010 ANGIOPLASTY SUMMIT ABSTRACTS/E-Poster 45B

E-POSTER

ABSTRACTS

Wednesday, April 28 - Friday, April 30, 2010 (E-Poster Abstract Zone)