analysis of surveillance data

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ANALYSIS OF SURVEILLANCE DATA Dr. Ronnie D. Domingo

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Page 1: Analysis of Surveillance Data

ANALYSIS OF SURVEILLANCE

DATADr. Ronnie D. Domingo

Page 2: Analysis of Surveillance Data

Design

formField data

gathering

Dataencodin

g

Data Analysi

s

ReportWritin

g

Data Processing

Page 3: Analysis of Surveillance Data

Data

pro

cess

ing

• Sorting• Coding• Editing • Summarizing

Data analysis

Page 4: Analysis of Surveillance Data

Data processing

• A series of steps undertaken to transform collected raw data into a form suitable for statistical analysis (Sanchez et al, 1989)

Page 5: Analysis of Surveillance Data

Data sorting method

• Types of data sheets• Numbering system for

data sheets (especially for surveys)

• The physical “container” for these raw data

Sorting

Coding

Editing

Summarizing

Page 6: Analysis of Surveillance Data

Data Coding• Examples

Data Possible codes

“Yes” answer Y or 1

“No” answer N or 2

No response 999 or U for unknown

Does not know 888 or D

Sorting

Coding

Editing

Summarizing

Page 7: Analysis of Surveillance Data

Data editing/ validation

Examine the data for four things: C.A.T.S.• Completeness• Accuracy• Traceability• Standard format

Sorting

Coding

Editing

Summarizing

Page 8: Analysis of Surveillance Data

Spreadsheet from Hell

By Daniel W. Byrne

Page 9: Analysis of Surveillance Data

Spreadsheet from Heaven

By Daniel W. Byrne

Page 10: Analysis of Surveillance Data

GIGO• Garbage In, Garbage Out

Page 11: Analysis of Surveillance Data

Form Level Validation:

• At the stage of filling up the online or printed form.

• Mandatory vs optional fields• INC entries= “SUBMIT” failD

ata

Vali

dat

ion

Page 12: Analysis of Surveillance Data

Field Level Validation:

• Field= space where you write the answer

• “Farmer’s Name” field = Fernan@do Cruz

• Date: 03-02-2016• Provide a list of possible

answers• Other fields auto appear or

disappear

Dat

a Va

lid

atio

n

Page 13: Analysis of Surveillance Data

Data Saving Validation:

• Option: keep the record as a draft copy vs “Submit” as final copy

• User with time to review and revise entries

Dat

a Va

lid

atio

n

Page 14: Analysis of Surveillance Data

Validation of Continuous Variables

• Continuous variables: age, height, weight, feed consumption, size of lesion, egg per gram of feces, temperature, etc.

• Check the following: – Minimum value– maximum value– mean– median

Vari

able

s

Page 15: Analysis of Surveillance Data

Validation techniques

Sample bar chart of lung score of pigs from several farm sources. The expected lung scores should range from 0-55. Note “farmer117” registered an erroneous lung score of 60.

Farmer1

11

Farmer1

12

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Farmer1

290

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Page 16: Analysis of Surveillance Data

Validation of Categorical Variables

• Categorical Variables –– nominal (sick, healthy)– ordinal (+,++, +++)

• Techniques:– Frequency checks– Cross Tabulations

Vari

able

s

Page 17: Analysis of Surveillance Data

Cross-check variables to detect awkward combinations.

Example a male dog positive for metritis.

Page 18: Analysis of Surveillance Data

Data Verification

• Comparing the output of two encoders

• Comparing the data on the screen against the original paper document.

• Comparing the print out of the computer database and the original printed document.

Page 19: Analysis of Surveillance Data

Summarizing the data

6400 records6002 usable398 rejected4565 from Bulacan1835 from Pampanga

83 other places2 files Abat.xls Farm.xls

Sorting

Coding

Editing

Summarizing

Page 20: Analysis of Surveillance Data

Design

formField data

gathering

Dataencodin

g

Data Analysi

s

ReportWritin

g

Data Processing

Page 21: Analysis of Surveillance Data

Data analysis

Page 22: Analysis of Surveillance Data

Data analysis: Tools

• Install statistical and graphics software packages

• Examples: SAS, SPSS, STATA, Epi Info, R software, Open Epi, Win Epi, QGIS

• Check the provider for newer software packages.

Page 23: Analysis of Surveillance Data

Type of Statistical Analysis

Page 24: Analysis of Surveillance Data

Descriptive statistics

Measures Descriptive StatisticsMeasures of central tendency

Mean, median, mode

Measures of variation Range, variance, standard deviation, standard error, confidence limits

Frequency distribution Counts or proportions in different groups; use frequency tables, histograms and other graphs for visual presentation

Rates and ratios Incidence, prevalence, etc.

Page 25: Analysis of Surveillance Data

Inferential statistics

Tests for difference Tests for Association

See next page Cohort study= Relative risk, attributable riskCase-control study = Odds ratioExperimental study = Protective valueCorrelation and regression analysis = linear relationship, non-linear relationship

From your sample, make inferences about the larger

population

Page 26: Analysis of Surveillance Data

Inferential statistics(deduce, generalize, extrapolate)

• Uses the theory of probability to make inferences about larger populations from your sample.

• The pattern seen in the analyzed sample is extrapolated to the target population.

Page 27: Analysis of Surveillance Data

Tests

Page 28: Analysis of Surveillance Data

Sample flow chart to select the appropriate statistical test

Page 29: Analysis of Surveillance Data

Essential components of a common report in veterinary

practice

Page 30: Analysis of Surveillance Data

Generate information from collected data.

Page 31: Analysis of Surveillance Data

Name the comic hero who caught this criminal?

Page 32: Analysis of Surveillance Data

The Phantom

Page 33: Analysis of Surveillance Data

Who visited this place?

Page 34: Analysis of Surveillance Data

Calling?

Page 35: Analysis of Surveillance Data

Every disease leaves a distinct

mark

Page 36: Analysis of Surveillance Data

Two premises of modern epidemiology:

Diseases in populations do not occur

in random fashion

Diseases in populations do have multiple determinants

Page 37: Analysis of Surveillance Data

Disease patterns are described based on three main epidemiologic variables:

Page 38: Analysis of Surveillance Data

Reasons for the Epi Triad:

• The three = most important;• The result= significant

information• The process= systematic• The by-product= hypothesis;• The output = transferable to

the stakeholders.

Page 39: Analysis of Surveillance Data

Information is processed data

Page 40: Analysis of Surveillance Data

Basic Activities: CDC

Count Aggregate the cases in the line listing by characteristic (e.g., place, animal, time)

Divide Divide the number of cases by the relevant denominator

Compare

Compare incidence across groups

Page 41: Analysis of Surveillance Data

Forms of analysis output

• Textual• Tabular• Graphical

Page 42: Analysis of Surveillance Data

Data Presentation: Graphical (Horizontal bar graph)

SFB

BFB

PFB

RFB

PGF

AAF

RDF

SCF

0 10 20 30 40 50 60 70 80 90

Proportion of positive samples (%)

Farm

Cod

e

Figure 1. Bar Graph of the proportion of Mycolasma hyopneumonia positive samples per farm of origin as detected by LAMP technique

Qualitative data

Page 43: Analysis of Surveillance Data

Data Presentation: Graphical (Vertical bar graph)

Aurora Bataan Bulacan N.Ecija Pampanga Tarlac Zambales -

50,000

100,000

150,000

200,000

250,000

300,000

350,000

Figure 1. Estimated dog population in the different provinces of Region III, 2013)

Qualitative data

Page 44: Analysis of Surveillance Data

2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 2012 20130

50

100

150

200

250

300

350

400

450

500

Data Presentation: Graphical (Line graph)

Figure 2. Secular trend of animal rabies in Central Luzon, 2002 to 2013.

ContinuousQuantitative

data

Page 45: Analysis of Surveillance Data

Data Presentation: Graphical (Pie Graph)

Bulacan20%

Nueva Ecija15%

Tarlac10%

Pampanga30%

Zambales7%

Aurora6%

Bataan12%

Figure 3. Rabies vaccine allotment to different provinces in Central Luzon, 2013

Page 46: Analysis of Surveillance Data

AnimalWhich type of animals are prone to develop the disease and which

type tends to be spared?

Page 47: Analysis of Surveillance Data

Common groupings employed in epidemiology

AgeSex

SpeciesBreed

Use

Page 48: Analysis of Surveillance Data

Disease patterns are described based on three main epidemiologic variables:

AgeSex

SpeciesBreed

Use

Page 49: Analysis of Surveillance Data

Classification of time trends

• Short term• Cyclical• Seasonal• Long-term

Page 50: Analysis of Surveillance Data

Graphs of endemic and sporadic diseases

Page 51: Analysis of Surveillance Data

January February March April May June July August September October November December0

5

10

15

20

25

Seasonal distribution of animal rabies in Central Luzon, 2002-2011

Month

Inci

denc

e co

unt o

f ani

mal

rabi

es

Page 52: Analysis of Surveillance Data

Disease patterns are described based on three main epidemiologic variables:

AgeSex

SpeciesBreed

Use

Short termCyclicalSeasonalLong-term

Page 53: Analysis of Surveillance Data

Surra Prevalence – CATT Percent Positive by Municipality

Source: EAHMI, based on data provided by PAHC and RADLs.

Page 54: Analysis of Surveillance Data

Types of Thematic Maps

1. Qualitative maps= maps that show non-measurable characteristics (e.g. Low and high rainfall).

2. Quantitative maps= maps that depict areas with measured variations

Page 55: Analysis of Surveillance Data

Qualitative Map

Geographic distribution of Japanese encephalitis

Page 56: Analysis of Surveillance Data

Types of quantitative maps: (a) Dot maps (b) Choropleth maps (c) Isopleth maps(d) Proportional symbol maps

Page 57: Analysis of Surveillance Data

Dot Maps

Page 58: Analysis of Surveillance Data

Choropleth maps

• Geographic areas are shaded or colored according to a prearranged key, each shading or color type corresponding to a range of values

• Commonly used in showing population density information

Page 59: Analysis of Surveillance Data

Isopleth Map

from iso meaning “equal” and pleth meaning “lines.”

Dot maps Choropleth maps Isopleth maps Proportional symbol maps

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