tumor board discussion

TUMOR BOARD DISCUSSION21.02.2014

Mrs. Panchavarnam 55/F

CA TONGUE – LAT. 1/3 rdSTAGE- cT3NOMOHPE—Well diff. sq. cell carcinoma

LOCALLY ADVANCED CA TONGUE

TREATMENT OF CHOICE 1. SURGERY→RT 2. RT→ SURGERY 3. CONCURRENT CHEMORT 4. NEO ADJUVANT CHEMO→CHEMORT

LOCALLY ADVANCED CA TONGUE

SIGNS OF INOPERABILITY 1. POST 1/3 TONGUE INVOLMENT 2. MANDIBLE INVOLMENT 3. COSMETIC/ FUNCTIONAL 4. ALL THE ABOVE

LOCALLY ADVANCED CA TONGUE

SURGERY 1. TRANSORAL 2. MANDIBULOTOMY

LOCALLY ADVANCED CA TONGUE

MANAGEMENT OF NECK 1. FOLLOW UP 2. RT 3. RADICAL NECK DISSECTION

LOCALLY ADVANCED CA TONGUE

NECK DISSECTION 1. RADICAL NECK DISSECTION 2. SELECTIVE NECK DISSECTION 3. SUPER SELECTIVE NECK

DISSECTION

LOCALLY ADVANCED CA TONGUE

RT 1. CONVENTIONAL RT 2. HYPERFRACTIONATED RT 3. ACCLERATED RT

LOCALLY ADVANCED CA TONGUE

RT TECHNIQUE 1. CONVENTIONAL 2. IMRT 3. PROTON THERAPY

LOCALLY ADVANCED CA TONGUE

CHEMO 1. PLATINUM BASED DOUBLETS 2. TPF 3. TPF⁺TARGETED AGENTS

LOCALLY ADVANCED CA TONGUE

EGFR DETECTION 1. IHC 2. OVER EXPRESSION 3. MUTATIONS 4. K RAS MUTATIONS

LOCALLY ADVANCED CA TONGUE

TARGETED AGENTS 1. CETUXIMAB 2. LAPATINIB 3. PANITUMUMAB 4. NIMOTUZUMAB 5. BEVACIZUMAB 6. EROLITINIB 7. GEFTINIB

LOCALLY ADVANCED CA TONGUE

HPV DETECTION 1. YES 2. NO 3. MAY BE