mik black nz society of oncologists 2010

Collaborative initiatives that are changing the face of cancer research ���

Mik Black���Department of Biochemistry���

University of Otago���

The good old days: sharing data

The good old days: sharing data

Oncomine: adding value

http://www.broadinstitute.org/cmap/

Nature Reviews Cancer, 2007: 7(1) 54-60

http://tcga.cancer.gov/

Nature (2008) vol. 455 (7216) pp. 1061-8

http://www.sanger.ac.uk/genetics/CGP/

http://www.icgc.org/

http://www.icgc.org/

http://cabig.cancer.gov/ https://cabig.nci.nih.gov/

http://cabig.cancer.gov/caBIGstory/vision/

http://cabig.cancer.gov/caBIGstory/mission/

http://cagrid.org/

BeSTGRID: Broadband-enabled Science and Technology GRID ���

http://www.bestgrid.org

BeSTGRID: Broadband-enabled Science and Technology GRID ���

http://www.bestgrid.org

Nick Jones Director, BeSTGRID Associate Director eResearch Centre for eResearch The University of Auckland n.jones@auckland.ac.nz

eResearch landscape

http://www.cellml.org

http://www.geneious.com/karen

http://biomirror.org.nz

http://sakai.bestgrid.org

A few BeSTGRID activities…

+ BLAST

Coming soon…

•  Large “meta-cohort” of public breast cancer samples: –  2116 patients: molecular, clinical, and treatment information

–  Collaboration with Assoc Prof Lance Miller (Wake Forest), Dr Heather Cunliffe (TGen), Assoc Prof Cris Print (Auckland).

•  Goal: molecular markers for personalized prediction: prognosis and response to treatment.

Putting the bits together…

Acknowledgements University of Otago Marcus Davy Thomas Allen Sarah Song Anthony Reeve Parry Guilford John McCall Tony Merriman

Translational Genomics (TGen) Heather Cunliffe

Wake Forest University Lance Miller

The University of Auckland Nick Jones Mark Gahegan Yuriy Halytskyy Cristin Print Daniel Hurley Christoff Knapp

University of Canterbury Vladimir Mencl