cns

Brain, diffuse laminar

necrosis and necrosis of

basal ganglia.Patient is in “persistent vegetative

state”

Pale infarct, middle cerebral artery

Hemorrhagic infarct, middle cerebral artery

Basal ganglia hemorrhage

Arteriosclerosis due to hypertension

Fibrinoid necrosis of intracerebral artery secondary to hypertension

Charcot-Bouchard microaneurysm with reticulin stain

Subarachnoid hemorrhage --

Brain, laminarnecrosis, focal

area

Venous angioma, Trichrome stain

Capillary telangiectasis

B12 deficiency: myelin loss in lateral and posterior columns

Alzheimer’s disease: amyloid in plaques and vessel walls

Alzheimer’s disease: plaques and tangles

Plaque with amyloid (red) and astrocytes (brown)

Normal midbrain (left) and Parkinson’s disease (right)Note loss of pigment in substantia nigra

Brain, Acute Meningitis, H&E

Brain, Granulomatous Meningitis, H&E

Brain, Ctyptococci in India ink preparation of CSF

Brain, Ctyptococcosis. Note spongy appearance

Brain, Small brain abscess, H&E.

Brain, Perivascular infiltration by lymphocytes in encephalitis, H&E

Brain, Neuronophagia in encephalitis, H&E

Brain, Microglial nodule in encephalitis, H&E

Brain, Intranuclear inclusion body in neurons in encephalitis, H&E

Brain, Intracytoplasmic inclusion in Purkinje cells in Rabies, H&E

Brain, Intranuclear inclusion in oligodendrocyte

Gray matter: Spongiform encephalopathy in Creutzfeldt-Jakob disease, H&E

Whorling of tumor cells in meningioma

Psammoma bodies

in meningioma

Astrocytoma in the temporal

lobe

Astrocytoma

Glioblastoma multiforme;pseudopalisades of tumor

cells around necrosis

Cystic astrocytoma of cerebellum

Oligodendroglioma

Calcification inoligodendroglioma

EpendymomaEpendymomain fourthin fourthventricleventricle

Ependymoma;perivascular

pseudo-rosettes

Homer Wright rosettes in

medulloblastoma

Antony A (dense area) and Antony B (pale area)

fibers of schwannoma

Subarachnoid hemorrhage

Capillary hemorrhages

Macrophages with hemosiderin

Multiple sclerosis

Multiple sclerosis

Multiple sclerosis plaque

Spinal cord section in multiple sclerosis

Tabes dorsalis