carlos montalvo foy h. moody high school; corpus christi isd faculty mentor: dr. zhengdong cheng
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Carlos Montalvo
Foy H. Moody High School; Corpus Christi ISD
Faculty Mentor: Dr. Zhengdong Cheng
Artie McFerrin Dept. of Chemical Engineering
B.S., University of Science and Technology of China, Hefei, China, 1990
M.S., Institute of High Energy Physics, Beijing, China, 1993
Ph.D., Princeton University, 1999 Postdoc, ExxonMobil, 1999-2000 DiCon Fiberoptics Inc., 2001-2002 Postdoc, Harvard Universtiy, 2002-
2004
Colloid Chemistry Colloid—type of mechanical mixture where one
substance is dispersed evenly throughout another.
Aspects of Research
Colloidal Crystal Growth Engineering and ordering large crystals to create
photonic band gaps for optical computers Discotic Colloids
Study the flow and movement of disk like molecules such as red blood cells
Cell Encapsulation Using microreactors to create a protective
“bubble” over a cell for possible drug delivery
Crystal Structure Review
How are Colloids and Crystal structures related?
Colloidal Crystals!!
89 min 152 min
0 min 4 min 11 min
25 min
Reason for Understanding Colloidal Crystals
Optical Computers
Optical Computer
Discotic Colloids
Emulsification—process by which one liquid is dispersed into another in the form of small droplets (http://www.pwsrcac.org/resources/glossary.html)
• Wax with 1% STADIS-450
• Flow Rate : 4ml/h
• Voltage: 2.8 kV
Electrospray
Electrospray Ionization technique
where droplets are created in an electric field
An electric force is applied to a liquid surface
Wax Emulsion
Eicosene (wax) Formation of
droplets Lower
temperature to form disks
Disk Forming
Electrospray cooling forms disks similar to shape of Red Blood Cell
Cell Encapsulation
Placing a cell into a protective membrane that is not immunosuppressed.
Cell Encapsulation: concept
Encapsulate cells of interest in semi-permeable membrane
Implant cell capsules Cells release therapeutic
substances Advantages
Immunoisolation Natural therapeutic response
Applications Diabetes (type I) Hemophilia Cancer Renal failure Dr. Dawei Luo
Cell Encapsulation
Confocal microscope imaging shows the uniform shape of alginate disks.
Fluorescence shows successful encapsulation of colloidal particles.
Microfluidics
Microfluidics
water
water
oil oil
oil oil
Microfluidics
Microreactors using microfluidics
Experiments to be Conducted
Formation of microdisks using Electrospray technique
Droplet Formation Using Electrospray
Experiments to be Conducted
Study the size and variation of the wax disks as electrospray settings are changed
Study how the disks flow through various substances (ie.—red blood cell flow)
Observe and study encapsulation techniques Attempt to add protective coating to
encapsulations
Aspects of Research Colloidal crystal growth Disk formation using Electrospray Cell encapsulation using Electrospray and
microfluidics
Classroom Activities???
Dr. Zhengdong Cheng Andres Mejia Lucas Kinard National Science Foundation
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